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Home  > Press Release  > Frosted branch angiitis after allogeneic haematopoietic stem cell transplantation in adult T-cell leukaemia-lymphoma

Frosted branch angiitis after allogeneic haematopoietic stem cell transplantation in adult T-cell leukaemia-lymphoma

Abstract

A 51-year-old woman was diagnosed with acute-type adult T-cell leukaemia-lymphoma associated with human T-cell lymphotropic virus type 1 (HTLV-1). Allogeneic haematopoietic stem cell transplantation (allogeneic HSCT) after a conditioning regimen with 12 Gy of total body irradiation, 120 mg/kg cyclophosphamide, and 12 g/m 2 cytarabine was done at the Institute of Medical Science, University of Tokyo Hospital in July, 2014. The patient had complete remission and her post-HSCT follow-up was uneventful without immunosuppressive agents at routine haematological examinations. No complications were identifed during routine ophthalmological examinations. However, 54 months after allogeneic HSCT, she complained of sudden blurred vision in both eyes and was referred to the eye clinic at Tokyo Medical and Dental University Hospital.

Journal Article

JOURNAL:
THE LANCET Haematology

TITLE:
Frosted branch angiitis after allogeneic haematopoietic stem cell transplantation in adult T-cell leukaemia-lymphoma

DOI:
https://doi.org/10.1016/S2352-3026(20)30226-X

Correspondence to

Koju KAMOI, M.D, Ph.D, Junior Associate Professor
Department of Ophthalmology and Visual Science,
Graduate School of Medical and Dental Sciences,
Tokyo Medical and Dental University(TMDU)
E-mail:koju.oph (at) tmd.ac.jp


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