Self vs Non-self discrimination in antiviral immune response by Kazuki Kato

1. Structural analysis of RIG-I-like receptors reveals ancient rules of engagement between diverse RNA helicases and TRIM ubiquitin ligases

Kazuki Kato, Sadeem Ahmad, Zixiang Zhu, Janet M Young, Xin Mu, Sehoon Park, Harmit S Malik and Sun Hur 

Publication: Molecular Cell
Publication Date: 28 December 2020
DOI: https://doi.org/10.1016/j.molcel.2020.11.047

2. Structure and engineering of the type III-E CRISPR-Cas7-11 effector complex

Kazuki Kato, Wenyuan Zhou, Sae Okazaki, Yukari Isayama, Tomohiro Nishizawa, Jonathan S. Gootenberg, Omar O. Abudayyeh and Hiroshi Nishimasu

Publication: Cell
Publication Date: 22 May 2022
DOI: https://doi.org/10.1016/j.cell.2022.05.003

3. RNA-triggered protein cleavage and cell growth arrest by the type III-E CRISPR nuclease-protease

Kazuki Kato, Sae Okazaki, Cian Schmitt-Ulms, Kaiyi Jiang, Wenyuan Zhou, Junichiro Ishikawa, Yukari Isayama, Shungo Adachi, Tomohiro Nishizawa, Kira S Makarova, Eugene V Koonin, Omar O Abudayyeh, Jonathan S Gootenberg and Hiroshi Nishimasu 

Publication: Science
Publication Date: 3 November 2022
DOI: https://doi.org/10.1126/science.add7347

Kazuki Kato, Associate Professor (PI)

E-mail: kato.kazuki(at)tmd.ac.jp

Department of Molecular and Mechanistic Immunology,
Graduate School of Medical and Dental Sciences, 
Tokyo Medical and Dental University(TMDU)

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