Press Release RSS 2023.12.01 Fri Press Release Elucidation of the needs for telecritical care services in Japan: a qualitative study 2023.11.29 Wed Press Release Ambient temperature and preterm birth: A case-crossover study 2023.11.28 Tue Press Release AAV-mediated editing of PMP22 rescues Charcot-Marie-Tooth disease type 1A features in patient-derived iPS Schwann cells 2023.11.27 Mon Press Release Site-specific photo-crosslinking/cleavage for protein–protein interface identification reveals oligomeric assembly of lysosomal-associated membrane protein type 2A in mammalian cells 2023.11.22 Wed Press Release Do disasters exacerbate socioeconomic inequalities in health among older people? 2023.11.17 Fri Press Release Inhibition of transforming growth factor-β signals suppresses tumor formation by regulation of tumor microenvironment networks 2023.11.09 Thu Press Release Machine Learning Models for Predicting Long-Term Visual Acuity in Highly Myopic Eyes 2023.11.08 Wed Press Release Pathogenicity of functionally activated PD-1⁺CD8⁺ cells and counterattacks by muscular PD-L1 through IFNγ in myositis 2023.11.08 Wed Press Release LRBA signalosomes activate vasopressin-induced AQP2 trafficking at recycling endosomes 2023.11.02 Thu Press Release Inflammasome-triggered IL-18 controls skin inflammation in the progression of Buruli ulcer 2023.10.25 Wed Press Release Chronic kidney disease causes blood-brain barrier breakdown via urea-activated matrix metalloproteinase-2 and insolubility of tau protein 2023.10.24 Tue Press Release Preventing Airborne Infection without Impeding Communication with Ions and Electric Field 2023.10.23 Mon Press Release Invasion of the bucco-mandibular space by oral squamous cell carcinoma: histopathological analysis of invasion pattern 2023.10.20 Fri Press Release Retrovirus-Derived RTL9 Plays an Important Role in Innate Antifungal Immunity in the Eutherian Brain 2023.10.17 Tue Press Release Finding your niche: a synthetic cancer stem cell microenvironment 2023.10.16 Mon Press Release National Trends in Mortality and Urgent Dialysis after Acute Hypertension in Japan From 2010 Through 2019 2023.10.16 Mon Press Release Development of bioinspired damage-tolerant calcium phosphate bulk materials 2023.10.13 Fri Press Release A MinION-based Long-Read Sequencing Application With One-Step PCR for the Genetic Diagnosis of 21-Hydroxylase Deficiency 2023.10.13 Fri Press Release Topical application of a PDE4 inhibitor ameliorates atopic dermatitis through inhibition of basophil IL-4 production 2023.10.10 Tue Press Release Loss of KDM6B epigenetically confers resistance to lipotoxicity in nonalcoholic fatty liver disease–related HCC 2023.10.06 Fri Press Release Researchers identify the variants responsible for a rare and serious disorder 2023.09.28 Thu Press Release Structure–Activity Relationship Studies of SARS-CoV-2 Main Protease Inhibitors Containing 4-Fluorobenzothiazole-2- carbonyl Moieties 2023.09.22 Fri Press Release Regression of periventricular anastomosis after indirect revascularization in pediatric patients with moyamoya disease 2023.09.21 Thu Press Release Killer smile? An oral pathogen increases heart attack damage 2023.09.21 Thu Press Release Synthesis of Multisubstituted Aromatics via 3-Triazenylarynes 2023.09.19 Tue Press Release Can ChatGPT diagnose your condition? Not yet 2023.09.14 Thu Press Release Prevalence of dental visits in older Japanese adults receiving public assistance 2023.09.13 Wed Press Release Activated Akt expression is associated with the recurrence of primary melanomas and further refines the prognostic and predictive values for relapse in acral melanomas 2023.09.12 Tue Press Release Reward expectation enhances action-related activity of nigral dopaminergic and two striatal output pathways 2023.09.06 Wed Press Release Oral Self-Care, Pneumococcal Vaccination, and Pneumonia Among Japanese Older People, Assessed With Machine Learning 2023.08.28 Mon Press Release Homemade blenderized tube feeding improves gut microbiome communities in children with enteral nutrition 2023.08.24 Thu Press Release The origins of blood: researchers identify a gene critical to blood production 2023.08.24 Thu Press Release Development of anti-HBV agents targeting HBV capsid proteins 2023.08.17 Thu Press Release A secret passage for mutant protein to invade the brain 2023.08.14 Mon Press Release New insights into the development of Parkinson’s disease in the brain 2023.08.09 Wed Press Release Augmented effect of fibroblast growth factor 18 in bone morphogenetic protein 2-induced calvarial bone healing by activation of CCL2/CCR2 axis on M2 macrophage polarization 2023.08.03 Thu Press Release Malnutrition- inflammation- atherosclerosis (MIA) syndrome associates with periodontitis in end-stage renal disease patients undergoing hemodialysis: a cross-sectional study 2023.07.25 Tue Press Release A new mechanism encouraging the brain to self-repair after an ischemic stroke 2023.07.24 Mon Press Release An international survey of allogeneic hematopoietic cell transplantation for X-linked agammaglobulinemia 2023.07.18 Tue Press Release The effect of breathing relaxation to improve poor sleep quality in adults using a huggable human-shaped device: a randomized controlled trial 2023.07.13 Thu Press Release CiDRE renders alveolar macrophages susceptible to SARS-CoV-2 invasion 2023.07.12 Wed Press Release Intracellular recycling: the key to surviving potent anti-cancer drugs 2023.07.11 Tue Press Release Association between place of dental check-ups and work absenteeism among Japanese workers 2023.07.06 Thu Press Release Development of small fluorescent probes for the analysis of autophagy kinetics 2023.07.06 Thu Press Release Association between Grit and depressive symptoms at the timing of job start among medical residents during the COVID-19 pandemic in Japan: a cross-sectional study 2023.07.03 Mon Press Release Identification of a Biallelic Missense Variant in Gasdermin D (c.823G > C, p.Asp275His) in a Patient of Atypical Gorham-Stout Disease in a Consanguineous Family 2023.06.30 Fri Press Release Successful generation of functional parathyroid glands from mouse embryonic stem cells 2023.06.30 Fri Press Release A screening method for cervical myelopathy using machine learning to analyze a drawing behavior 2023.06.27 Tue Press Release Reconsidering economic interventions to reduce oral health inequalities 2023.06.23 Fri Press Release A novel bone regeneration technique with clinical potential 2023.06.19 Mon Press Release Personal immune profiles: Diversity and prognostic value for oral tongue squamous cell carcinoma evaluated by comprehensive immune parameter analyses with multiplex immunofluorescence 2023.06.16 Fri Press Release Signaling mechanisms in renal compensatory hypertrophy revealed by multi-omics 2023.06.13 Tue Press Release Loss of SFXN1 mitigates lipotoxicity and predicts poor outcome in non-viral hepatocellular carcinoma 2023.06.09 Fri Press Release Quantitative analysis and correlative evaluation of video-oculography, micro-computed tomography, and histopathology in Pendrin-null mice 2023.06.06 Tue Press Release Screening for degenerative cervical myelopathy with the 10-second grip-and-release test using a smartphone and machine learning: A pilot study 2023.06.01 Thu Press Release Indirect CRISPR screening with photoconversion revealed key factors of drug resistance with cell–cell interactions 2023.05.25 Thu Press Release When it comes to COVID-19, belly fat upsets the apple cart 2023.05.24 Wed Press Release Tap water natural fluoride and parent-reported experience of child dental caries in Japan: Evidence from a nationwide birth cohort survey 2023.05.23 Tue Press Release MGMT is frequently inactivated in pancreatic NET-G2 and is associated with the therapeutic activity of STZ-based regimens 2023.05.19 Fri Press Release A new, promising weapon in the fight against HIV 2023.05.18 Thu Press Release Pre-basophils: a basophil origin story 2023.05.15 Mon Press Release Red Pill or Blue Pill? The Critical Decision to Control the Superbugs 2023.04.18 Tue Press Release Molecular autopsy sheds light on cause of sudden death of a child with COVID-19 2023.04.13 Thu Press Release Further link identified between autoimmunity and schizophrenia 2023.04.11 Tue Press Release Hanging on for dear life 2023.04.10 Mon Press Release Maternal and early-life high-fat diets result in a taste for salty food 2023.04.03 Mon Press Release Relevance of leukaemia inhibitory factor to anti-melanoma differentiation-associated gene 5 antibody-positive interstitial lung disease 2023.03.30 Thu Press Release Association of Stressful Life Events with Oral Health Among Japanese Workers 2023.03.27 Mon Press Release Integrator complex subunit 15 controls mRNA splicing and is critical for eye development 2023.03.24 Fri Press Release Three-dimensional visualization of neural networks inside bone by Osteo-DISCO protocol and alteration of bone remodeling by surgical nerve ablation 2023.03.16 Thu Press Release Effects of tongue right positioner use on tongue pressure: a pilot study 2023.03.13 Mon Press Release Enteral liquid ventilation oxygenates a hypoxic pig model 2023.03.09 Thu Press Release Analysis of swallowing function after anterior/posterior surgery for cervical degenerative disorders and factors related to the occurrence of postoperative dysphagia 2023.03.06 Mon Press Release Lipid molecules help to get stroke therapies into the brain 2023.03.03 Fri Press Release RTP4 silencing provokes tumor-intrinsic resistance to immune checkpoint blockade in colorectal cancer 2023.03.02 Thu Press Release The “Wishbone” Charm that Restores the Hope for Bone Regeneration 2023.02.20 Mon Press Release Filling a Niche: Neural Stem Cells Help Maintain Their Microenvironment 2023.02.13 Mon Press Release Link between chronic kidney disease and cardiovascular disease explained 2023.02.03 Fri Press Release Fabrication of milled removable partial dentures using a custom plate with prefabricated artificial teeth 2023.02.02 Thu Press Release ZNF185 prevents stress fiber formation through the inhibition of RhoA in endothelial cells 2023.02.01 Wed Press Release A Call for Action Mounts an Emergent Attack Against Invaders 2023.02.01 Wed Press Release Effects of thickened carbonated cola in older patients with dysphagia 2023.01.31 Tue Press Release Transporting antibodies across the blood–brain barrier to treat Alzheimer’s disease 2023.01.30 Mon Press Release A Sight for Sore Eyes: Anti-VEGF Treatment in an Ocular Model of Viral Infection 2023.01.19 Thu Press Release New university name "Institute of Science Tokyo” (tentative) to be submitted to ministry council 2023.01.13 Fri Press Release Validity of the KOJI AWARENESS self-screening test for body movement and comparison with functional movement screening 2023.01.12 Thu Press Release FLIP-based autophagy-detecting technique reveals closed autophagic compartments 2023.01.04 Wed Press Release Mind your Qs: polyQ-binding protein 5 scaffolds the nucleolus 2022.12.27 Tue Press Release Calcium: a key player for a promising and safe brain treatment? 2022.12.27 Tue Press Release Tears in Tokyo: Muscle–tendon injuries during Olympic competition can spell heartbreak 2022.12.21 Wed Press Release Evidence showing the ‘loosening of associations’ found in schizophrenia 2022.12.19 Mon Press Release Biomolecular Analyses Now Have an Expanded Chemical Toolkit 2022.12.13 Tue Press Release RNA-binding protein LIN28A upregulates transcription factor HIF1α by post-transcriptional regulation via direct binding to UGAU motifs 2022.12.12 Mon Press Release Quenchbody Immunosensors Pave the Way to Quick and Sensitive COVID-19 Diagnostics 2022.12.02 Fri Press Release From grave to cradle: collagen-induced gut cell reprogramming 2022.11.18 Fri Press Release Xanthan gum-based fluid thickener can help decrease blood glucose levels 2022.11.16 Wed Press Release The future of replacement organs is (quite possibly) here: robust human intestinal organoids created in a lab 2022.11.10 Thu Press Release New targets in the fight against pancreatic cancer 2022.11.09 Wed Press Release New STAT1-us quo? Novel STAT1 variants cause MSMD 2022.11.02 Wed Press Release Expanding the arsenal of drugs against COVID-19 2022.10.14 Fri Press Release Basic Agreement for Integration Signed 2022.10.14 Fri Press Release Diabetic status modifies the impact of an NAFLD-associated SNP 2022.10.05 Wed Press Release Remdesivir reduces COVID-19 mortality in a real-world setting 2022.09.28 Wed Press Release Stopping the spread: targeting tumor metastasis 2022.09.26 Mon Press Release WNK1/HSN2 mediates neurite outgrowth and differentiation via a OSR1/GSK3β-LHX8 pathway 2022.09.07 Wed Press Release Differences in trunk and lower extremity muscle activity during squatting exercise with and without hammer swing 2022.09.06 Tue Press Release Transistors help identify cancer cell markers 2022.09.04 Sun Press Release Promotion of Cancer Progression Via Extracellular Vesicles 2022.08.24 Wed Press Release A new data analysis approach identifies disease-associated splicing variants 2022.08.19 Fri Press Release Urgent dialysis during hospitalization for surgery predicts poor outcomes 2022.08.04 Thu Press Release A Pill to Strengthen Muscle and Bone 2022.08.04 Thu Press Release Mitigating RANKL-induced cholesterol overload in macrophages with β-cyclodextrin-threaded polyrotaxanes suppresses osteoclastogenesis 2022.07.29 Fri Press Release Summer is the Season of Caution: Extreme Heat Events Mean Higher Risk for Diabetics 2022.07.22 Fri Press Release A Matter of Concentration: Molecular Mechanisms of Water Homeostasis 2022.07.21 Thu Press Release Roles of IGFBP-3 in cell migration and growth in an endophytic tongue squamous cell carcinoma cell line 2022.07.20 Wed Press Release Building Better Gas-phase Biosensors for Fight Against Diseases 2022.07.20 Wed Press Release IPGaia, Inc. and Tokyo Medical and Dental University Announce Master Collaborative Research and Development Agreement 2022.07.15 Fri Press Release The role of programmed cell death ligand-1 on Langerhans cells in the regulation of psoriasis 2022.07.07 Thu Press Release The Tokyo Medical and Dental University (TMDU) team succeeded with the world’s first Mini Organ transplantation to a patient with “Ulcerative Colitis (UC)” 2022.07.06 Wed Press Release A novel drug suppresses muscle inflammation and restores muscle weakness 2022.06.30 Thu Press Release cGAS-STING signaling encourages immune cell overcoming of fibroblast barricades in pancreatic cancer 2022.06.24 Fri Press Release Higher extracellular water/total body water ratio is associated with lower tongue and grip strength: a cross-sectional study 2022.06.02 Thu Press Release Move over muscles, it’s time for tendons to be in the spotlight 2022.05.21 Sat Press Release The Role of Long Non-coding RNA MALAT1 in Diabetic Polyneuropathy and the Impact of its Silencing in the Dorsal Root Ganglion by a DNA/RNA Heteroduplex Oligonucleotide 2022.05.20 Fri Press Release A crystal ball in the fight against esophageal cancer 2022.05.10 Tue Press Release Methodology to Detect Biological Particles Using a Biosensing Surface Integrated in Resistive Pulse Sensing 2022.05.09 Mon Press Release A Titanic Medical Discovery 2022.04.20 Wed Press Release Body versus brain: New evidence for an autoimmune cause of schizophrenia 2022.04.15 Fri Press Release Time Spent Away from Bed to Maintain Swallowing Function in Older Adults 2022.04.15 Fri Press Release Development of a classifier for gambling disorder based on functional connections between brain regions 2022.04.12 Tue Press Release blaKPC-2-Encoding IncP-6 Plasmids in Citrobacter freundii and Klebsiella variicola Strains from Hospital Sewage in Japan 2022.04.11 Mon News TMDU is ranked 1st for dentistry and 4th for medicine in Japan, and 6th for dentistry and 135th for medicine in the world from QS World University Rankings 2022 by Subject! 2022.04.01 Fri Press Release Regulation of activated microglia and macrophages by systemically administered DNA/RNA heteroduplex oligonucleotides 2022.03.29 Tue Press Release CD34+THY1+ synovial fibroblast subset in arthritic joints has high osteoblastic and chondrogenic potentials in vitro 2022.03.09 Wed Press Release Anti-cancer dream cream shrinks oral tumors 2022.03.09 Wed Press Release Hematopoietic Cell Transplantation for Inborn Errors of Immunity Other than Severe Combined Immunodeficiency in Japan: Retrospective Analysis for 1985–2016 2022.03.07 Mon Press Release Fujitsu and Tokyo Medical and Dental University leverage world’s fastest supercomputer and AI technology for scientific discovery to shed light on drug resistance in cancer treatment 2022.03.03 Thu Press Release Versatile Design of Intracellular Protein-Responsive Translational Regulation System for Synthetic mRNA 2022.03.02 Wed Press Release Two-faced protein both inhibits and activates B cell receptor signaling 2022.02.28 Mon Press Release Enhanced O-GlcNAc modification induced by the RAS/MAPK/CDK1 pathway is required for SOX2 protein expression and generation of cancer stem cells 2022.02.24 Thu Press Release Resourceful viral protein combats monkey and human defenses differently 2022.02.18 Fri Press Release Low Jaw Strength reflects Hard to Swallow in Old Age 2022.02.08 Tue Press Release Revealing the function of Mkx in periodontal ligament homeostasis 2022.02.08 Tue Press Release Two ovarian candidate enhancers, identified by time series enhancer RNA analyses, harbor rare genetic variations identified in ovarian insufficiency 2022.02.03 Thu Press Release Infusion of 3D cellular structures might repair damaged intestine 2022.02.02 Wed Press Release Heterogeneity of intrinsic plasticity in cerebellar Purkinje cells linked with cortical molecular zones 2022.02.01 Tue Press Release Axcelead Begins Joint Research with Tokyo Medical and Dental University on mRNA Drug Development for Acute Cerebral Infarction and Postresuscitation Encephalopathy 2022.01.27 Thu Press Release Connecting science to medicine: tendon-like tissue created from human stem cells 2022.01.26 Wed Press Release Dynamic stem cell selection safeguards the genomic integrity of the epidermis 2022.01.20 Thu Press Release Predicting the Progression of Rheumatoid Arthritis 2022.01.17 Mon Press Release Characteristics of SARS-CoV-2 super-spreaders in Japan 2022.01.14 Fri Press Release Development of an intervention system for linkage-to-care and follow-up for hepatitis B and C virus carriers 2022.01.13 Thu Press Release Seeing Lipids More Deeply with Mass Spectrometry 2022.01.10 Mon Press Release Targeting Necroptosis for Inflammatory Myopathies 2022.01.05 Wed Press Release HTLV-1 uveitis and Graves' disease presenting with sudden onset of blurred vision 2021.12.28 Tue Press Release The Xa Factor : Pushing Back on Atherosclerosis 2021.12.22 Wed Press Release How a Two-Faced Molecule Can Silence Problematic Genes 2021.12.22 Wed Press Release Dorsal telencephalon-specific Nprl2- and Nprl3-knockout mice: Novel mouse models for GATORopathy 2021.11.30 Tue Press Release Development of polysaccharide-based carriers that enhance antibody production to target molecules 2021.11.29 Mon Press Release New AI System Provides the Consistent Endoscopic evaluation 2021.11.19 Fri Press Release Jigsaw-Shaped Peptide Solves Tissue Regeneration Puzzle 2021.11.15 Mon Press Release Tau and PQBP1: Protein Interaction Induces Inflammation in the Brain 2021.11.09 Tue Press Release Impact of School Closure Due to COVID-19 on the Social-Emotional Skills of Japanese Pre-school Children 2021.11.05 Fri Press Release The Placenta - the Smoking Gun in Cardiovascular Disease 2021.11.04 Thu Press Release Burden of kidney disease on the discrepancy between reasons for hospital admission and death: An observational cohort study 2021.11.02 Tue Press Release Higher Activity and Quality of Life Correlates with Swallowing Function in Older Adults with Low Activities of Daily Living 2021.10.28 Thu Press Release That’s so meta(transcriptomics): distinctive bacterial taxonomic and functional profiles in mouth disease 2021.10.28 Thu Press Release MRI before biopsy correlates with depth of invasion corrected for shrinkage rate of the histopathological specimen in tongue carcinoma 2021.10.11 Mon Press Release HMGB1 signaling phosphorylates Ku70 and impairs DNA damage repair in Alzheimer’s disease pathology 2021.10.05 Tue Press Release Bringing cells closer to form new tissues 2021.09.22 Wed Press Release Skin stem cells get moving for enhanced skin regeneration 2021.09.21 Tue Press Release Drilling into the Dental Secrets of Edo-era Japanese Bacterial Genomes 2021.09.06 Mon Press Release Blue Is The Clue To Evaluating Diabetic Retinopathy 2021.08.26 Thu Press Release Genetic variant linked to prognosis of chronic hypersensitivity pneumonitis 2021.08.24 Tue Press Release Getting to the root of tooth replantation challenges 2021.08.24 Tue Press Release Intrinsic activation of β-catenin signaling by CRISPR/Cas9-mediated exon skipping contributes to immune evasion in hepatocellular carcinoma 2021.08.18 Wed Press Release Effects of Oral Management on Elderly Patients with Pneumonia 2021.08.17 Tue Press Release Integrating Data to Find a Cure 2021.08.17 Tue Press Release Age-related changes in swallowing muscle intramuscular adipose tissue deposition and related factors 2021.08.13 Fri Press Release From blood to brain: delivering nucleic acid therapy to the CNS 2021.08.12 Thu Press Release One protein to rule them all: a central target for treating dementia 2021.08.05 Thu Press Release Super-Enhancers: The Villain Fueling Certain Cancers 2021.07.29 Thu Press Release Hepta-Histidine Inhibits Tau Aggregation 2021.07.26 Mon Press Release Selective β2-Adrenoceptor Blockade Rescues Mandibular Growth Retardation in Adolescent Rats Exposed to Chronic Intermittent Hypoxia 2021.07.14 Wed Press Release Restoring healthy gut bacteria through blood stem cell transplantation 2021.07.06 Tue Press Release Getting You Moving Again: A Possible New Treatment for Joint Issues 2021.07.05 Mon Press Release Importance of telomere shortening in the pathogenesis of ulcerative colitis: A new treatment from the aspect of telomeres in intestinal epithelial cells 2021.07.01 Thu Press Release Comparison of Clinicopathological Characteristics Between the Anterior and Posterior Type of Squamous Cell Carcinoma of the Floor of the Mouth: The Anterior Type Is a Risk Factor for Multiple Primary Cancer 2021.06.29 Tue Press Release Small but Powerful: A Tiny Molecule with Massive Anti-Cancer Potential 2021.06.28 Mon Press Release A breath of fresh air for emphysema research 2021.06.28 Mon Press Release Heterozygous OAS1 gain-of-function variants cause an autoinflammatory immunodeficiency 2021.06.24 Thu Press Release Eating Less Fat May Save Your Hair 2021.06.22 Tue Press Release When mad AIOLOS drags IKAROS down: a novel pathogenic mechanism 2021.06.21 Mon Press Release m6A-mediated alternative splicing coupled with nonsense-mediated mRNA decay regulates SAM synthetase homeostasis 2021.06.21 Mon Press Release External ears for non-invasive and stable monitoring of volatile organic compounds in human blood 2021.06.15 Tue Press Release DNA damage in embryonic neural stem cell determines FTLDs’ fate via early-stage neuronal necrosis 2021.06.01 Tue Press Release Industry-Academia Collaborated Microstructure Spine-Fusing Device Now Covered Under Japanese National Health Insurance 2021.05.27 Thu Press Release No IgA leads to intestinal inflammation in mice 2021.05.26 Wed Press Release Identification of PDHX as a metabolic target for esophageal squamous cell carcinoma 2021.05.26 Wed Press Release Synergy of molecularly mobile polyrotaxane surfaces with endothelial cell co-culture for mesenchymal stem cell mineralization 2021.05.25 Tue Press Release Dental is the new mental: retaining natural teeth reduces depression symptoms 2021.05.20 Thu Press Release Using Mice to Open the Way to Prevent Blocked Arteries 2021.05.19 Wed Press Release HERV-Derived Ervpb1 Is Conserved in Simiiformes, Exhibiting Expression in Hematopoietic Cell Lineages Including Macrophages 2021.05.19 Wed Press Release Schlafen 11 is a novel target for mucosal regeneration in Ulcerative Colitis 2021.05.15 Sat Press Release Ventilating the rectum to support respiration 2021.05.07 Fri Press Release Emergence of oxacillinase-181 carbapenemase-producing diarrheagenic Escherichia coli in Ghana 2021.04.30 Fri Press Release Making sense of antisense gene silencing 2021.04.26 Mon Press Release A promising new target for urinary tract infections and kidney stones 2021.04.15 Thu Press Release Lighting the LAMP to Reveal Mystery of Lysosomes 2021.04.14 Wed Press Release Multilevel Analysis of the Association of Dental-Hygienist-Related Factors on Regular Dental Check-Up Behavior 2021.04.05 Mon Press Release Effect of isometric exercises on the masseter muscle in older adults with missing dentition: a randomized controlled trial 2021.04.02 Fri Press Release Dental Pain and Worsened Socioeconomic Conditions Due to the COVID-19 Pandemic 2021.03.30 Tue Press Release AI spots healthy stem cells quickly and accurately 2021.03.30 Tue Press Release Food for thought: Eating soft foods may alter the brain’s control of chewing 2021.03.29 Mon Press Release Factors affecting mental illness and social stress in hospital workers treating COVID-19: Paradoxical distress during pandemic era 2021.03.25 Thu Press Release Horizontal transmission can cause severe and persistent eye inflammation 2021.03.19 Fri Press Release Development of Methods for Convergent Synthesis of Chloroalkene Dipeptide Isosteres and Its Application 2021.03.18 Thu Press Release A missense variant in NUF2, a component of the kinetochore NDC80 complex, causes impaired chromosome segregation and aneuploidy associated with microcephaly and short stature 2021.03.18 Thu Press Release Sparsely methylated mitochondrial cell free DNA released from cardiomyocytes contributes to systemic inflammatory response accompanied by atrial fibrillation 2021.03.16 Tue Press Release Risk factors for distant metastasis in locoregionally controlled oral squamous cell carcinoma: a retrospective study 2021.03.12 Fri Press Release A new polarized fluorescent probe for revealing architectural dynamics of living cells 2021.03.08 Mon News TMDU is ranked 1st for dentistry and 4th for medicine in Japan, and 5th for dentistry and 114th for medicine in the world from QS World University Rankings 2021 by Subject! 2021.03.04 Thu Press Release Finding clues to nephronophthisis in adults 2021.03.01 Mon Press Release Common Origin of the Cerebellar Dual Somatotopic Areas Revealed by Tracking Embryonic Purkinje Cell Clusters with Birthdate Tagging 2021.02.22 Mon Press Release An antibody-drug combo to combat cancer 2021.02.12 Fri Press Release The bald truth – altered cell divisions cause hair thinning 2021.02.05 Fri Press Release Keep it Moving: How a Biomaterial Mobility May Revolutionize Immunomodulation 2021.02.03 Wed Press Release Small-molecule anti-HIV-1 agents based on HIV-1 capsid proteins 2021.01.28 Thu Press Release A new agent for the brain diseases: mRNA 2021.01.27 Wed Press Release HIV has been Had 2021.01.25 Mon Press Release Get Your Head in the Game – One Gene’s Role in Cranial Development 2021.01.18 Mon Press Release Living for Today: Exposure to Disaster May Cause Impatience in Children 2021.01.14 Thu Press Release The Jaws of Life – How Hypoxia Exposure Affects Jaw Cartilage Growth 2021.01.12 Tue Press Release Lighting Up Bone Repair 2020.12.23 Wed Press Release A New Type of Recyclable: Finding New Uses for Established Drugs 2020.12.09 Wed Press Release Dual effect of molecular mobility and functional groups of polyrotaxane surfaces on the fate of mesenchymal stem cells 2020.12.07 Mon Press Release Making therapeutic sense of antisense oligonucleotides 2020.12.03 Thu Press Release Esophageal Cancer Patients Show Abundance of Oral Pathogens 2020.11.30 Mon Press Release Fluctuation in radioresponse of HeLa cells during the cell cycle evaluated based on micronucleus frequency 2020.11.26 Thu Press Release Reversible Stickiness is Something to Smile About 2020.11.25 Wed Press Release A subtle change in the DNA may predispose to polyneuropathy after gut infection 2020.11.24 Tue Press Release Ultrasonography Shows Age-related Changes and Related Factors in the Tongue and Suprahyoid Muscles 2020.11.24 Tue Press Release Melatonin: Finally, a supplement that actually boosts memory 2020.11.24 Tue Press Release Improving the Efficacy of EGFR Inhibitors by Topical Treatment of Cutaneous Squamous Cell Carcinoma with miR-634 Ointment 2020.11.20 Fri Press Release β-AR Agonist Therapy Puts the Brakes on Oral Cancer Progression 2020.11.17 Tue Press Release How poor oral hygiene may result in metabolic syndrome 2020.11.13 Fri Press Release WNK regulates Wnt signalling and β-Catenin levels by interfering with the interaction between β-Catenin and GID 2020.11.10 Tue Press Release Fujitsu and Tokyo Medical and Dental University Leverage World’s Fastest Supercomputer to Perform Cancer Gene Network Analysis in Less than a Day 2020.10.29 Thu Press Release TMDU is ranked #79 for Clinical & Health in THE World University Rankings by Subject 2021! 2020.10.28 Wed Press Release A missense mutation in the RSRSP stretch of Rbm20 causes dilated cardiomyopathy and atrial fibrillation in mice 2020.10.21 Wed Press Release Taking Out the Trash is Essential for Brain Health 2020.10.20 Tue Press Release Viewing upper gastrointestinal cancers in a new light 2020.10.19 Mon Press Release HFD-induced hepatic lipid accumulation and inflammation are decreased in Factor D deficient mouse 2020.10.16 Fri Press Release Hinder Handing the Message– Stopping Tumors from Creating New Blood Vessels 2020.09.23 Wed Press Release The natural artistry of disease: a wintry landscape in the eye 2020.09.14 Mon Press Release Nothing but the Truth in the Fight Against Cancer 2020.09.11 Fri Press Release Menstrual cycle length and body temperature change with age and seasons 2020.09.08 Tue Press Release Predicting the future of liver-safe drugs 2020.09.08 Tue Press Release IRF2 maintains the stemness of colonic stem cells by limiting physiological stress from interferon 2020.09.03 Thu Press Release Generation of three-dimensional heart organoids 2020.09.02 Wed Press Release RTL1 Gene a Likely Culprit Behind Temple and Kagami-Ogata Syndromes 2020.08.27 Thu Press Release Increasing the Effectiveness of Cancer Treatments: Anti-PD-L1 Immunotherapy 2020.08.12 Wed Press Release Light stimulation makes bones heavier 2020.07.27 Mon Press Release Targeting all transforming growth factor-β isoforms with an Fc chimeric receptor impairs tumor growth and angiogenesis of oral squamous cell cancer 2020.07.21 Tue Press Release A new molecular guardian of intestinal stem cells 2020.07.20 Mon Press Release The key royal jelly component 10-hydroxy-2-decenoic acid protects against bone loss via FFAR4 2020.07.14 Tue Press Release Shigella prevents infected cells from sacrificing themselves for the greater good 2020.07.13 Mon Press Release Tumor progression depends on the tumor microenvironment 2020.07.03 Fri Press Release Opening an autophagy window as the apoptosis door starts to close 2020.06.30 Tue Press Release Joint Research Coronavirus Task Force Established to Promote Research and Development of COVID-19 Vaccine for Mucosal Immunity Based on Genetic Findings of the Novel Coronavirus Disease 2020.06.26 Fri Press Release Potential target identified for migraine therapy 2020.06.17 Wed Press Release Hollow fiber-combined glucose-responsive gel technology as an in vivo electronics-free insulin delivery system 2020.06.02 Tue Press Release In vitro neo-genesis of tendon-like tissue by combination of Mohawk and a three-dimensional cyclic mechanical stretch culture system 2020.06.01 Mon Press Release Lin28a/let-7 Pathway Modulates the Hox Code via Polycomb Regulation during Axial Patterning in Vertebrates 2020.06.01 Mon Press Release “Opening of an open-laboratory for research into next generation ventilators, and for evaluation and research, etc. of new ventilator types, with a view towards responding to the surge in numbers of novel coronavirus patients” 2020.05.25 Mon Press Release Characterization of radioresistant epithelial stem cell heterogeneity in the damaged mouse intestine 2020.05.22 Fri Press Release How Stress Affects Bone Marrow 2020.05.13 Wed Press Release Glioma stem cell (GSC)‐derived autoschizis‐like products confer GSC niche properties involving M1‐like tumor‐associated macrophages 2020.05.07 Thu Press Release Analysis of the mouse Y chromosome by single molecule sequencing with Y chromosome enrichment. 2020.04.23 Thu Press Release Human Lifelong Immunity Depends on APRIL 2020.04.20 Mon Press Release miR-1293, a candidate for miRNA-based cancer therapeutics, simultaneously targets BRD4 and the DNA repair pathway 2020.04.17 Fri Press Release Overlapping but asymmetrical relationships between schizophrenia and autism revealed by brain connectivity 2020.04.10 Fri Press Release How Cells Decide the Way They Want to Recycle Their Content 2020.04.02 Thu Press Release Tolerogenic properties of CD206+ macrophages appeared in the sublingual mucosa after repeated antigen-painting 2020.03.06 Fri Press Release TMDU is ranked 1st (Dentistry in Japan) and 4th (Medicine in Japan) in QS World University Rankings 2020 by Subject! 2020.03.02 Mon Press Release Effectiveness of using an educational video simulating the anatomical mechanism of shaking and smothering in a home visit program to prevent self reported infant abuse 2020.03.02 Mon Press Release Using artificial intelligence to assess ulcerative colitis 2020.02.12 Wed Press Release Researchers Link Immune System to Salt-Sensitive Hypertension in CKD 2020.02.12 Wed Press Release A Joint Clinical Research Collaboration among Tokyo Medical and Dental University (TMDU), ACT Genomics , and ACTmed Seeks to Investigate the Cancer Genomic Landscape of Japanese Population 2020.01.31 Fri Press Release Estradiol/GPER affects the integrity of mammary duct-like structures in vitro 2020.01.28 Tue Press Release A Filter for Cleaner Qubits 2020.01.23 Thu Press Release Timing of Brain Cell Death Uncovers a New Target for Alzheimer’s Treatment 2020.01.15 Wed Press Release Cannabidiol suppresses the induction of neoplastic osteoclasts – Aiming to develop new therapeutic agents against cancer-induced bone destruction— 2020.01.08 Wed Press Release Development of anticancer drug with tumor-suppressive <i>miR-634</i> as a drug seed for the nucleic acid therapeutics 2020.01.08 Wed Press Release Vpu Protein of Simian Immunodeficiency Virus Isolated from a Monkey Species Living in Africa Overcomes Function of Human Antiviral Protein BST-2 2019.12.27 Fri Press Release "Elucidating the relationship of oral nutrition to systemic health" -Oral and gut microbiome are key: prospects for improvement of medical care through dysphagia rehabilitation- 2019.12.25 Wed Press Release Seeing the Invisible – A Novel Gas Imaging System 2019.12.23 Mon Press Release "Intracellular localization of claudin-1 at the invasive front of tongue cancer is associated with lymph node metastasis” 2019.12.02 Mon Press Release TMDU is ranked #74 for Clinical, Pre-clinical & Health in THE World University Rankings by Subject 2020! 2019.11.27 Wed Press Release Temporospatial sonic hedgehog signalling is essential for neural crest-dependent patterning of the intrinsic tongue musculature 2019.11.06 Wed Press Release Bile duct biomarker? Protein found to pinpoint patients with a lethal cancer 2019.11.01 Fri Press Release A Nice Reactive Ring to It: New Synthetic Pathways for Diverse Aromatic Compounds 2019.10.21 Mon Press Release “Instant Liver, Just Add Water”? Not Quite, but a Better Way to Grow Multiple Organs 2019.09.24 Tue Press Release Comparative analysis demonstrates cell type-specific conservation of SOX9 targets between mouse and chicken 2019.09.11 Wed Press Release Stem cell competition offers a mechanism for skin youthfulness and ageing 2019.08.06 Tue Press Release Heterogeneity in fetal growth velocity 2019.08.02 Fri Press Release 3D miniature livers lead the way to patient-specific drug discovery 2019.07.30 Tue Press Release Involvement of N-type Ca2+ channel in microglial activation and its implications to aging-induced exaggerated cytokine response 2019.07.24 Wed Press Release "HDO-antimiR represents a new weapon in the fight against microRNA-related disease" 2019.07.04 Thu Press Release Enhancement of Motor Function Recovery After Spinal Cord Injury in Mice by Delivery of Brain Derived Neurotrophic Factor mRNA 2019.07.03 Wed Press Release Fibroblast growth factor signals regulate transforming growth factor‐β‐induced endothelial‐to‐myofibroblast transition of tumor endothelial cells via Elk1 2019.07.01 Mon Press Release Tolvaptan activates the Nrf2/HO-1 antioxidant pathway through PERK phosphorylation 2019.06.28 Fri Press Release 3-Thioaryne Intermediates for the Synthesis of Diverse Thioarenes 2019.06.25 Tue Press Release Blockade of microglial Cav1.2 Ca2+ channel exacerbates the symptoms in a Parkinson’s disease model 2019.06.13 Thu Press Release Reciprocal cortical activation patterns during incisal and molar biting correlated with bite force levels: an fMRI study. 2019.06.05 Wed Press Release MRTF A regulates proliferation and survival properties of pro atherogenic macrophages 2019.06.04 Tue Press Release Wwp2 maintains cartilage homeostasis through regulation of Adamts5. 2019.05.31 Fri Press Release Modeling Steatohepatitis in Human with Pluripotent Stem Cell-Derived Organoids 2019.05.29 Wed Press Release Antibacterial activity of lysozyme-chitosan oligosaccharide conjugates (LYZOX) against Pseudomonas aeruginosa, Acinetobacter baumannii and Methicillin-resistant Staphylococcus aureus 2019.05.10 Fri Press Release “Hard food, strong jaw: jawbone structure responds to forceful chewing” 2019.04.23 Tue Press Release Synthesis of Alkynyl Sulfides by Copper-Catalyzed Thiolation of Terminal Alkynes Using Thiosulfonates 2019.04.16 Tue Press Release Silencing of PD-L2/B7-DC by Topical Application of Small Interfering RNA Inhibits Elicitation of Contact Hypersensitivity 2019.04.16 Tue Press Release ”Genome editing helps decipher a congenital liver disease” 2019.04.12 Fri Press Release Development of a NanoBRET-based Sensitive Screening Method for CXCR4 Ligands 2019.04.10 Wed Press Release Impact of novel NS5A resistance-associated substitutions of hepatitis C virus detected in treatment-experienced patients 2019.03.19 Tue Press Release Loss of Fibrocystin Promotes Interleukin-8-Dependent Proliferation and CTGF Production of Biliary Epithelium 2019.03.15 Fri Press Release "How does estrogen protect bones? Unraveling a pathway to menopausal bone loss" 2019.03.11 Mon Press Release TMDU is ranked 1st (Dentistry in Japan) and 3rd (Medicine in Japan) in QS World University Rankings 2019 by Subject! 2019.03.07 Thu Press Release A facile preparation of functional cycloalkynes via an azide-to-cycloalkyne switching approach 2019.02.26 Tue Press Release Treatment of intervertebral disk disease by administration of messenger RNA encoding a cartilage-anabolic transcription factor 2019.02.15 Fri Press Release LIM homeobox 2 promotes interaction between human iPS-derived hepatic progenitors and iPS-derived hepatic stellate-like cells 2019.02.08 Fri Press Release "Adenoid and Tonsil Trouble for Teens" 2019.02.06 Wed Press Release "Shedding Light on Zebrafish Daily Rhythms: Clock Gene Functions Revealed" 2019.02.05 Tue Press Release Interleukin-13 receptor α2 is a novel marker and potential therapeutic target for human melanoma 2019.01.31 Thu Press Release "Crunching the Data: New Liver Cancer Subtypes Revealed Immunologically" 2019.01.24 Thu Press Release "Researchers Breathe New Life into COPD Research Using Mouse Models" 2019.01.24 Thu Press Release Induced Proton Perturbation for Sensitive and Selective Detection of Tight Junction Breakdown 2019.01.17 Thu Press Release ”Killer Blows? Knockout Study of Pair of Mouse MicroRNA Provides Cancer Insight” 2018.12.20 Thu Press Release Short-term prognosis of emergently hospitalized dialysis-independent chronic kidney disease patients: a nationwide retrospective cohort study in Japan 2018.12.18 Tue Press Release Loss of KDM6A characterizes a poor prognostic subtype of human pancreatic cancer and potentiates HDAC inhibitor lethality 2018.12.14 Fri Press Release "Stop that clot! Quantitative assessment of the blood coagulation cascade" 2018.12.13 Thu Press Release Ubiquitin D is up-regulated by synergy of Notch signaling and TNF-α in the inflamed intestinal epithelia of IBD patients. 2018.12.07 Fri Press Release "Undiplomatic Immunity: Mutation Causing Arterial Autoimmune Disease Revealed" 2018.12.07 Fri Press Release "Faulty sensing: cellular energy sensor linked to the progression of chronic kidney disease" 2018.12.04 Tue Press Release Asymmetric dimethylation at histone H3 arginine 2 by PRMT6 in gastric cancer progression 2018.11.08 Thu Press Release "Small populations of normal cells affect immunity in patients with XLP1" 2018.10.29 Mon Press Release "Virus Production Boosted in Cells to Generate More Vectors for Gene Transfer" 2018.10.22 Mon Press Release Gain-of-function IKBKB mutation causes human combined immune deficiency 2018.10.11 Thu Press Release "Early Changes to Synapse Gene Regulation May Cause Alzheimer’s Disease" 2018.08.24 Fri Press Release Combinatorial CRISPR/Cas9 approach to elucidate a far-upstream enhancer complex for tissue-specific Sox9 expression 2018.08.17 Fri Press Release Downregulated Pancreatic Beta Cell Genes Indicate Poor Prognosis in Patients With Pancreatic Neuroendocrine Neoplasms. 2018.08.16 Thu Press Release "Controlling STAT3 may provide new therapy for chronic active Epstein-Barr virus infection, a chemotherapy-resistant T- or NK-cell neoplasm" 2018.08.06 Mon Press Release Integrated analysis of human genetic association study and mouse transcriptome suggests <i>LBH</i> and <i>SHF</i> genes as novel susceptible genes for amyloid-beta accumulation in Alzheimer's disease. 2018.07.19 Thu Press Release Histamine Released From Skin-Infiltrating Basophils but Not Mast Cells Is Crucial for Acquired Tick Resistance in Mice. 2018.07.05 Thu Press Release "New microsensor for pH mapping joins the fight against tooth decay" 2018.06.20 Wed Press Release "Opening Up a Drug Delivery Route – Discovery of a New Vehicle Peptide" 2018.06.20 Wed Press Release "Of Hearts and Giants: Moving a Cardiac Regulatory Protein to the Right Place" 2018.06.19 Tue Press Release Transient Protection of Organic Azides from Click Reactions with Alkynes by Phosphazide Formation. 2018.06.19 Tue Press Release Angubindin-1 opens the blood-brain barrier in vivo for delivery of antisense oligonucleotide to the central nervous system. 2018.06.12 Tue Press Release Multi-ethnic genome-wide association study for atrial fibrillation 2018.06.06 Wed Press Release Cytosolic Genomic DNA functions as a Natural Antisense 2018.06.05 Tue Press Release Hematopoietic stem cell transplantation for progressive combined immunodeficiency and lymphoproliferation in patients with activated phosphatidylinositol-3-OH kinase δ syndrome type 1. 2018.05.22 Tue Press Release Staudinger reaction using 2,6-dichlorophenyl azide derivatives for robust aza-ylide formation applicable to bioconjugation in living cells 2018.05.07 Mon Press Release Region-specific deletions of the glutamate transporter GLT1 differentially affect nerve injury-induced neuropathic pain in mice. 2018.05.07 Mon Press Release Stable lines and clones of long-term proliferating normal, genetically unmodified murine common lymphoid progenitors 2018.04.27 Fri Press Release Dissecting the roles of miR-140 and its host gene 2018.04.26 Thu Press Release Overexpression of heart-specific small subunit of myosin light chain phosphatase results in heart failure and conduction disturbance. 2018.04.17 Tue Press Release CD22-Binding Synthetic Sialosides Regulate B Lymphocyte Proliferation Through CD22 Ligand-Dependent and Independent Pathways, and Enhance Antibody Production in Mice. 2018.04.13 Fri Press Release AKAPs-PKA disruptors increase AQP2 activity independently of vasopressin in a model of nephrogenic diabetes insipidus 2018.04.04 Wed Press Release IMSindel: An accurate intermediate-size indel detection tool incorporating de novo assembly and gapped global-local alignment with split read analysis 2018.04.03 Tue Press Release Ovarian cancer therapeutic potential of glutamine depletion based on GS expression. 2018.03.26 Mon Press Release "Colon Signaling Pathway Key to Inflammatory Bowel Disease" 2018.03.19 Mon Press Release "Forming and resorbing bones: metastasizing cancer cells modify bone remodeling with small RNA secretion" 2018.03.13 Tue Press Release "Potential RNA Markers of Abnormal Heart Rhythms Identified in Circulating Blood" 2018.03.06 Tue Press Release "Technique Allows Live Imaging of “Ubiquitous” Player in Cellular Housekeeping" 2018.03.06 Tue Press Release "Epigenetic Modulation of Fgf21 Gene in Early-Life Ameliorates Adulthood Diet-Induced Obesity " 2018.02.23 Fri Press Release "Insights into familial middle-age dementia suggest new avenues for treatment" 2018.01.16 Tue Press Release Microneedle‐Array Patch Fabricated with Enzyme‐Free Polymeric Components Capable of On‐Demand Insulin Delivery 2018.01.12 Fri Press Release "Protein YAP in Early Life Influences Adult Spinocerebellar Ataxia Pathology" 2017.12.27 Wed Press Release "Uncovering Molecular Targets for Childhood Cancer Therapeutics" 2017.12.12 Tue Press Release "Role of Transcriptional Co-factor in Inflammation Hints at Possible Inflammatory Bowel Disease Treatment" 2017.12.08 Fri Press Release "Monitoring Thyroid Response: Biomarker May Predict Graves’ Disease Relapse" 2017.10.20 Fri Press Release "RANKL expressed by osteocytes has an important role in orthodontic tooth movement" 2017.10.18 Wed Press Release ”Superior vena cava (or SVC) - derived atrial fibrillation attributes to both clinical and genetic factors” 2017.08.17 Thu Press Release ”Signaling Pathway Controls Body Clock and Movement in Adult Mice” 2017.08.08 Tue Press Release "Protein critical to early stages of cellular HIV infection identified" 2017.08.01 Tue Press Release "Gene-Regulatory Factors Shown to Improve Pancreatic Cancer Response to Chemotherapy" 2017.08.01 Tue Press Release ”Molecule’s Role in Maintaining Liver Size and Function Revealed” 2017.07.10 Mon Press Release "Reduced mastication results in the impairment of memory and learning function" 2017.06.13 Tue Press Release "Discovery of Human Blood Cell Destinies Revises Knowledge of Immune Cell Development" 2017.05.25 Thu Press Release "A Lightning-Fast Flu Virus Detector" 2017.03.30 Thu Press Release "Differences in Microbial Interactions Underlie Related Oral Diseases" 2017.03.30 Thu Press Release "Method Identified to Boost Detection of Highly Cancerous Stem Cells" 2017.03.24 Fri Press Release "New Synthetic Route to Complex Organofluorine Compounds Developed" 2017.01.17 Tue Press Release "Metabolic Pathway Regulating Key Stage of Embryo Development Revealed" 2016.12.28 Wed Press Release "Role of Sox17 Protein in Embryo Implantation Key to Mouse Fertility" 2016.12.27 Tue Press Release "Alzheimer’s Disease Pathway Identification Enables Development of Novel Preclinical Therapy" 2016.12.16 Fri Press Release "Degrader of Proteins Required for the Origin of Early Cancerous Lesions" 2016.12.14 Wed Press Release "Breakthrough in Hepatitis Research as New Infected Cell Models are Developed" 2016.11.24 Thu Press Release "Novel Method of Cellular Waste Disposal Revealed in Yeast and Mammals" 2016.11.24 Thu Press Release ”Role for Autophagic Cellular Degradation Process in Maintaining Genomic Stability” 2016.11.22 Tue Press Release "How Cell Populations Weed Out “Loser” Cells to Maintain Vitality is Revealed" 2016.11.22 Tue Press Release ”Novel Type of Cell Death in Huntington’s Disease May Lead to Effective New Therapies” 2016.10.31 Mon Press Release “Advancing Our Understanding of How the Disease Lupus is prevented in healthy individuals” 2016.10.05 Wed Press Release “Breakthrough for Bone Regeneration via Double-cell-layered Tissue Engineering Technique” 2016.08.23 Tue Press Release “Injected Mix of Bone-augmenting Agents Causes New Bone Growth in Mouse Jaws” 2016.07.01 Fri Press Release “Blood Coagulation Detector May Help in Monitoring Stroke Risk” 2016.06.07 Tue Press Release “World's First Measurement and Visualization of Cardiac Activity Using MR Sensors” 2016.02.16 Tue Press Release “Periodic injections of synovial stem cells inhibit osteoarthritis progression in the knee” 2016.02.01 Mon Press Release “Synthetic polymer-based elucidation of survival strategies of cancer stem cells” 2015.12.28 Mon Event “Tooth regenerative technology by a mechanical ligation method” 2015.11.26 Thu Press Release Tokyo Medical and Dental University (TMDU) becomes the first university in Japan to establish an international joint degree (JD) program, and has concluded an agreement with University of Chile and its associated hospital. 2015.11.26 Thu Press Release Tokyo Medical and Dental University (TMDU) becomes the first university in Japan allowed to establish an international joint degree (JD) program having an agreement with Chulalongkorn University. 2015.09.29 Tue Press Release Tokyo Medical and Dental University to establish an INCJ-backed venture company, Rena Therapeutics Inc. 2015.08.11 Tue Press Release “DNA/RNA Heteroduplex oligonucleotide: the third class oligonucleotides” 2015.04.28 Tue News “Highly efficient CRISPR knock-in in mouse” 2014.12.16 Tue Press Release “Gene therapy of model mice for spinocerebellar ataxia was successful.” 2014.08.18 Mon Press Release “Transplanting Cultured Small Intestinal Epithelial Stem Cells onto Colon” 2014.04.23 Wed Press Release “Discovery of the molecule Sox17 to maintain the hematopoietic stem cell at embryonic stages” 2014.02.04 Tue Press Release “Identification of new molecular function that suppresses osteoporosis” 2013.09.13 Fri Press Release “Discovery of a novel function of dendritic cells to fine-tune excessive immune responses” 2013.04.26 Fri Press Release “Discovery of a novel source of dendritic cells, the control tower of the immune system” 2013.02.22 Fri Press Release “Identification of a novel mechanism by which allergic inflammation is dampened” 2012.10.11 Thu Press Release “3D MRI Analyses Clarify that Pathologic Myopia is Caused by Eye Globe Deformity” 2012.05.21 Mon Press Release “Etiologic Link between Sarcoidosis and Propionibacterium acnes” 2012.04.24 Tue Press Release “Anabolic action of PTH regulated by the β2-adrenergic receptor” 2012.03.12 Mon Press Release “Functional Engraftment of Colon Epithelium Expanded In Vitro from a Single Adult Lgr5+ Stem Cell” 2012.02.27 Mon Event “Identification of a key regulator molecule that prevents neutrophil over-activation” 2012.02.07 Tue Press Release “Dissecting molecular mechanisms of tumor progression” 2012.01.18 Wed Event “Development of non-human primate model of amyotrophic lateral sclerosis (ALS)” 2011.10.11 Tue Press Release “Sympathetic control of bone mass regulated by osteopontin” 2011.09.28 Wed Press Release “A Single-Use, Centrifugal Type Assist Heart with Excellent Durability and Biocompatibility” 2011.09.20 Tue Event “Identification of the commander cell in the bone remodeling” 2011.08.26 Fri Event “The first genetically engineered mouse model of diffuse-type gastric cancer” 2011.04.15 Fri Press Release “Autophagy prevents spontaneous tumor development in the liver” 2011.02.04 Fri Press Release “Hair Follicle Stem Cells Provide a Functional Niche for Melanocyte Stem Cells” 2010.07.27 Tue Press Release “Basophils Play an Essential Role in Protective Immunity Against Ticks” 2010.06.08 Tue Event “Clarification of a molecular mechanism underlying cerebellar degeneration” 2010.05.04 Tue Event “Impairment of DNA-repair by mutant Huntingtin is a major cause of neurodegenerative pathology in Huntington’s disease.” 2010.04.12 Mon Event “Identification of the gene regulating the development of T cells that cause autoimmune diseases” 2010.02.26 Fri Press Release
2023.12.01 Fri Press Release Elucidation of the needs for telecritical care services in Japan: a qualitative study
2023.11.28 Tue Press Release AAV-mediated editing of PMP22 rescues Charcot-Marie-Tooth disease type 1A features in patient-derived iPS Schwann cells
2023.11.27 Mon Press Release Site-specific photo-crosslinking/cleavage for protein–protein interface identification reveals oligomeric assembly of lysosomal-associated membrane protein type 2A in mammalian cells
2023.11.22 Wed Press Release Do disasters exacerbate socioeconomic inequalities in health among older people?
2023.11.17 Fri Press Release Inhibition of transforming growth factor-β signals suppresses tumor formation by regulation of tumor microenvironment networks
2023.11.09 Thu Press Release Machine Learning Models for Predicting Long-Term Visual Acuity in Highly Myopic Eyes
2023.11.08 Wed Press Release Pathogenicity of functionally activated PD-1⁺CD8⁺ cells and counterattacks by muscular PD-L1 through IFNγ in myositis
2023.11.08 Wed Press Release LRBA signalosomes activate vasopressin-induced AQP2 trafficking at recycling endosomes
2023.11.02 Thu Press Release Inflammasome-triggered IL-18 controls skin inflammation in the progression of Buruli ulcer
2023.10.25 Wed Press Release Chronic kidney disease causes blood-brain barrier breakdown via urea-activated matrix metalloproteinase-2 and insolubility of tau protein
2023.10.24 Tue Press Release Preventing Airborne Infection without Impeding Communication with Ions and Electric Field
2023.10.23 Mon Press Release Invasion of the bucco-mandibular space by oral squamous cell carcinoma: histopathological analysis of invasion pattern
2023.10.20 Fri Press Release Retrovirus-Derived RTL9 Plays an Important Role in Innate Antifungal Immunity in the Eutherian Brain
2023.10.16 Mon Press Release National Trends in Mortality and Urgent Dialysis after Acute Hypertension in Japan From 2010 Through 2019
2023.10.16 Mon Press Release Development of bioinspired damage-tolerant calcium phosphate bulk materials
2023.10.13 Fri Press Release A MinION-based Long-Read Sequencing Application With One-Step PCR for the Genetic Diagnosis of 21-Hydroxylase Deficiency
2023.10.13 Fri Press Release Topical application of a PDE4 inhibitor ameliorates atopic dermatitis through inhibition of basophil IL-4 production
2023.10.10 Tue Press Release Loss of KDM6B epigenetically confers resistance to lipotoxicity in nonalcoholic fatty liver disease–related HCC
2023.10.06 Fri Press Release Researchers identify the variants responsible for a rare and serious disorder
2023.09.28 Thu Press Release Structure–Activity Relationship Studies of SARS-CoV-2 Main Protease Inhibitors Containing 4-Fluorobenzothiazole-2- carbonyl Moieties
2023.09.22 Fri Press Release Regression of periventricular anastomosis after indirect revascularization in pediatric patients with moyamoya disease
2023.09.14 Thu Press Release Prevalence of dental visits in older Japanese adults receiving public assistance
2023.09.13 Wed Press Release Activated Akt expression is associated with the recurrence of primary melanomas and further refines the prognostic and predictive values for relapse in acral melanomas
2023.09.12 Tue Press Release Reward expectation enhances action-related activity of nigral dopaminergic and two striatal output pathways
2023.09.06 Wed Press Release Oral Self-Care, Pneumococcal Vaccination, and Pneumonia Among Japanese Older People, Assessed With Machine Learning
2023.08.28 Mon Press Release Homemade blenderized tube feeding improves gut microbiome communities in children with enteral nutrition
2023.08.24 Thu Press Release The origins of blood: researchers identify a gene critical to blood production
2023.08.09 Wed Press Release Augmented effect of fibroblast growth factor 18 in bone morphogenetic protein 2-induced calvarial bone healing by activation of CCL2/CCR2 axis on M2 macrophage polarization
2023.08.03 Thu Press Release Malnutrition- inflammation- atherosclerosis (MIA) syndrome associates with periodontitis in end-stage renal disease patients undergoing hemodialysis: a cross-sectional study
2023.07.25 Tue Press Release A new mechanism encouraging the brain to self-repair after an ischemic stroke
2023.07.24 Mon Press Release An international survey of allogeneic hematopoietic cell transplantation for X-linked agammaglobulinemia
2023.07.18 Tue Press Release The effect of breathing relaxation to improve poor sleep quality in adults using a huggable human-shaped device: a randomized controlled trial
2023.07.11 Tue Press Release Association between place of dental check-ups and work absenteeism among Japanese workers
2023.07.06 Thu Press Release Development of small fluorescent probes for the analysis of autophagy kinetics
2023.07.06 Thu Press Release Association between Grit and depressive symptoms at the timing of job start among medical residents during the COVID-19 pandemic in Japan: a cross-sectional study
2023.07.03 Mon Press Release Identification of a Biallelic Missense Variant in Gasdermin D (c.823G > C, p.Asp275His) in a Patient of Atypical Gorham-Stout Disease in a Consanguineous Family
2023.06.30 Fri Press Release Successful generation of functional parathyroid glands from mouse embryonic stem cells
2023.06.30 Fri Press Release A screening method for cervical myelopathy using machine learning to analyze a drawing behavior
2023.06.19 Mon Press Release Personal immune profiles: Diversity and prognostic value for oral tongue squamous cell carcinoma evaluated by comprehensive immune parameter analyses with multiplex immunofluorescence
2023.06.16 Fri Press Release Signaling mechanisms in renal compensatory hypertrophy revealed by multi-omics
2023.06.13 Tue Press Release Loss of SFXN1 mitigates lipotoxicity and predicts poor outcome in non-viral hepatocellular carcinoma
2023.06.09 Fri Press Release Quantitative analysis and correlative evaluation of video-oculography, micro-computed tomography, and histopathology in Pendrin-null mice
2023.06.06 Tue Press Release Screening for degenerative cervical myelopathy with the 10-second grip-and-release test using a smartphone and machine learning: A pilot study
2023.06.01 Thu Press Release Indirect CRISPR screening with photoconversion revealed key factors of drug resistance with cell–cell interactions
2023.05.24 Wed Press Release Tap water natural fluoride and parent-reported experience of child dental caries in Japan: Evidence from a nationwide birth cohort survey
2023.05.23 Tue Press Release MGMT is frequently inactivated in pancreatic NET-G2 and is associated with the therapeutic activity of STZ-based regimens
2023.04.18 Tue Press Release Molecular autopsy sheds light on cause of sudden death of a child with COVID-19
2023.04.03 Mon Press Release Relevance of leukaemia inhibitory factor to anti-melanoma differentiation-associated gene 5 antibody-positive interstitial lung disease
2023.03.30 Thu Press Release Association of Stressful Life Events with Oral Health Among Japanese Workers
2023.03.27 Mon Press Release Integrator complex subunit 15 controls mRNA splicing and is critical for eye development
2023.03.24 Fri Press Release Three-dimensional visualization of neural networks inside bone by Osteo-DISCO protocol and alteration of bone remodeling by surgical nerve ablation
2023.03.16 Thu Press Release Effects of tongue right positioner use on tongue pressure: a pilot study
2023.03.09 Thu Press Release Analysis of swallowing function after anterior/posterior surgery for cervical degenerative disorders and factors related to the occurrence of postoperative dysphagia
2023.03.03 Fri Press Release RTP4 silencing provokes tumor-intrinsic resistance to immune checkpoint blockade in colorectal cancer
2023.02.13 Mon Press Release Link between chronic kidney disease and cardiovascular disease explained
2023.02.03 Fri Press Release Fabrication of milled removable partial dentures using a custom plate with prefabricated artificial teeth
2023.02.02 Thu Press Release ZNF185 prevents stress fiber formation through the inhibition of RhoA in endothelial cells
2023.01.31 Tue Press Release Transporting antibodies across the blood–brain barrier to treat Alzheimer’s disease
2023.01.30 Mon Press Release A Sight for Sore Eyes: Anti-VEGF Treatment in an Ocular Model of Viral Infection
2023.01.19 Thu Press Release New university name "Institute of Science Tokyo” (tentative) to be submitted to ministry council
2023.01.13 Fri Press Release Validity of the KOJI AWARENESS self-screening test for body movement and comparison with functional movement screening
2023.01.12 Thu Press Release FLIP-based autophagy-detecting technique reveals closed autophagic compartments
2022.12.27 Tue Press Release Tears in Tokyo: Muscle–tendon injuries during Olympic competition can spell heartbreak
2022.12.13 Tue Press Release RNA-binding protein LIN28A upregulates transcription factor HIF1α by post-transcriptional regulation via direct binding to UGAU motifs
2022.12.12 Mon Press Release Quenchbody Immunosensors Pave the Way to Quick and Sensitive COVID-19 Diagnostics
2022.11.18 Fri Press Release Xanthan gum-based fluid thickener can help decrease blood glucose levels
2022.11.16 Wed Press Release The future of replacement organs is (quite possibly) here: robust human intestinal organoids created in a lab
2022.09.26 Mon Press Release WNK1/HSN2 mediates neurite outgrowth and differentiation via a OSR1/GSK3β-LHX8 pathway
2022.09.07 Wed Press Release Differences in trunk and lower extremity muscle activity during squatting exercise with and without hammer swing
2022.08.24 Wed Press Release A new data analysis approach identifies disease-associated splicing variants
2022.08.19 Fri Press Release Urgent dialysis during hospitalization for surgery predicts poor outcomes
2022.08.04 Thu Press Release Mitigating RANKL-induced cholesterol overload in macrophages with β-cyclodextrin-threaded polyrotaxanes suppresses osteoclastogenesis
2022.07.29 Fri Press Release Summer is the Season of Caution: Extreme Heat Events Mean Higher Risk for Diabetics
2022.07.21 Thu Press Release Roles of IGFBP-3 in cell migration and growth in an endophytic tongue squamous cell carcinoma cell line
2022.07.20 Wed Press Release IPGaia, Inc. and Tokyo Medical and Dental University Announce Master Collaborative Research and Development Agreement
2022.07.15 Fri Press Release The role of programmed cell death ligand-1 on Langerhans cells in the regulation of psoriasis
2022.07.07 Thu Press Release The Tokyo Medical and Dental University (TMDU) team succeeded with the world’s first Mini Organ transplantation to a patient with “Ulcerative Colitis (UC)”
2022.07.06 Wed Press Release A novel drug suppresses muscle inflammation and restores muscle weakness
2022.06.30 Thu Press Release cGAS-STING signaling encourages immune cell overcoming of fibroblast barricades in pancreatic cancer
2022.06.24 Fri Press Release Higher extracellular water/total body water ratio is associated with lower tongue and grip strength: a cross-sectional study
2022.05.21 Sat Press Release The Role of Long Non-coding RNA MALAT1 in Diabetic Polyneuropathy and the Impact of its Silencing in the Dorsal Root Ganglion by a DNA/RNA Heteroduplex Oligonucleotide
2022.05.10 Tue Press Release Methodology to Detect Biological Particles Using a Biosensing Surface Integrated in Resistive Pulse Sensing
2022.04.20 Wed Press Release Body versus brain: New evidence for an autoimmune cause of schizophrenia
2022.04.15 Fri Press Release Time Spent Away from Bed to Maintain Swallowing Function in Older Adults
2022.04.15 Fri Press Release Development of a classifier for gambling disorder based on functional connections between brain regions
2022.04.12 Tue Press Release blaKPC-2-Encoding IncP-6 Plasmids in Citrobacter freundii and Klebsiella variicola Strains from Hospital Sewage in Japan
2022.04.11 Mon News TMDU is ranked 1st for dentistry and 4th for medicine in Japan, and 6th for dentistry and 135th for medicine in the world from QS World University Rankings 2022 by Subject!
2022.04.01 Fri Press Release Regulation of activated microglia and macrophages by systemically administered DNA/RNA heteroduplex oligonucleotides
2022.03.29 Tue Press Release CD34+THY1+ synovial fibroblast subset in arthritic joints has high osteoblastic and chondrogenic potentials in vitro
2022.03.09 Wed Press Release Hematopoietic Cell Transplantation for Inborn Errors of Immunity Other than Severe Combined Immunodeficiency in Japan: Retrospective Analysis for 1985–2016
2022.03.07 Mon Press Release Fujitsu and Tokyo Medical and Dental University leverage world’s fastest supercomputer and AI technology for scientific discovery to shed light on drug resistance in cancer treatment
2022.03.03 Thu Press Release Versatile Design of Intracellular Protein-Responsive Translational Regulation System for Synthetic mRNA
2022.02.28 Mon Press Release Enhanced O-GlcNAc modification induced by the RAS/MAPK/CDK1 pathway is required for SOX2 protein expression and generation of cancer stem cells
2022.02.08 Tue Press Release Two ovarian candidate enhancers, identified by time series enhancer RNA analyses, harbor rare genetic variations identified in ovarian insufficiency
2022.02.02 Wed Press Release Heterogeneity of intrinsic plasticity in cerebellar Purkinje cells linked with cortical molecular zones
2022.02.01 Tue Press Release Axcelead Begins Joint Research with Tokyo Medical and Dental University on mRNA Drug Development for Acute Cerebral Infarction and Postresuscitation Encephalopathy
2022.01.27 Thu Press Release Connecting science to medicine: tendon-like tissue created from human stem cells
2022.01.26 Wed Press Release Dynamic stem cell selection safeguards the genomic integrity of the epidermis
2022.01.14 Fri Press Release Development of an intervention system for linkage-to-care and follow-up for hepatitis B and C virus carriers
2022.01.05 Wed Press Release HTLV-1 uveitis and Graves' disease presenting with sudden onset of blurred vision
2021.12.22 Wed Press Release Dorsal telencephalon-specific Nprl2- and Nprl3-knockout mice: Novel mouse models for GATORopathy
2021.11.30 Tue Press Release Development of polysaccharide-based carriers that enhance antibody production to target molecules
2021.11.09 Tue Press Release Impact of School Closure Due to COVID-19 on the Social-Emotional Skills of Japanese Pre-school Children
2021.11.04 Thu Press Release Burden of kidney disease on the discrepancy between reasons for hospital admission and death: An observational cohort study
2021.11.02 Tue Press Release Higher Activity and Quality of Life Correlates with Swallowing Function in Older Adults with Low Activities of Daily Living
2021.10.28 Thu Press Release That’s so meta(transcriptomics): distinctive bacterial taxonomic and functional profiles in mouth disease
2021.10.28 Thu Press Release MRI before biopsy correlates with depth of invasion corrected for shrinkage rate of the histopathological specimen in tongue carcinoma
2021.10.11 Mon Press Release HMGB1 signaling phosphorylates Ku70 and impairs DNA damage repair in Alzheimer’s disease pathology
2021.08.26 Thu Press Release Genetic variant linked to prognosis of chronic hypersensitivity pneumonitis
2021.08.24 Tue Press Release Intrinsic activation of β-catenin signaling by CRISPR/Cas9-mediated exon skipping contributes to immune evasion in hepatocellular carcinoma
2021.08.17 Tue Press Release Age-related changes in swallowing muscle intramuscular adipose tissue deposition and related factors
2021.07.26 Mon Press Release Selective β2-Adrenoceptor Blockade Rescues Mandibular Growth Retardation in Adolescent Rats Exposed to Chronic Intermittent Hypoxia
2021.07.05 Mon Press Release Importance of telomere shortening in the pathogenesis of ulcerative colitis: A new treatment from the aspect of telomeres in intestinal epithelial cells
2021.07.01 Thu Press Release Comparison of Clinicopathological Characteristics Between the Anterior and Posterior Type of Squamous Cell Carcinoma of the Floor of the Mouth: The Anterior Type Is a Risk Factor for Multiple Primary Cancer
2021.06.28 Mon Press Release Heterozygous OAS1 gain-of-function variants cause an autoinflammatory immunodeficiency
2021.06.21 Mon Press Release m6A-mediated alternative splicing coupled with nonsense-mediated mRNA decay regulates SAM synthetase homeostasis
2021.06.21 Mon Press Release External ears for non-invasive and stable monitoring of volatile organic compounds in human blood
2021.06.15 Tue Press Release DNA damage in embryonic neural stem cell determines FTLDs’ fate via early-stage neuronal necrosis
2021.06.01 Tue Press Release Industry-Academia Collaborated Microstructure Spine-Fusing Device Now Covered Under Japanese National Health Insurance
2021.05.26 Wed Press Release Identification of PDHX as a metabolic target for esophageal squamous cell carcinoma
2021.05.26 Wed Press Release Synergy of molecularly mobile polyrotaxane surfaces with endothelial cell co-culture for mesenchymal stem cell mineralization
2021.05.25 Tue Press Release Dental is the new mental: retaining natural teeth reduces depression symptoms
2021.05.19 Wed Press Release HERV-Derived Ervpb1 Is Conserved in Simiiformes, Exhibiting Expression in Hematopoietic Cell Lineages Including Macrophages
2021.05.19 Wed Press Release Schlafen 11 is a novel target for mucosal regeneration in Ulcerative Colitis
2021.05.07 Fri Press Release Emergence of oxacillinase-181 carbapenemase-producing diarrheagenic Escherichia coli in Ghana
2021.04.14 Wed Press Release Multilevel Analysis of the Association of Dental-Hygienist-Related Factors on Regular Dental Check-Up Behavior
2021.04.05 Mon Press Release Effect of isometric exercises on the masseter muscle in older adults with missing dentition: a randomized controlled trial
2021.04.02 Fri Press Release Dental Pain and Worsened Socioeconomic Conditions Due to the COVID-19 Pandemic
2021.03.30 Tue Press Release Food for thought: Eating soft foods may alter the brain’s control of chewing
2021.03.29 Mon Press Release Factors affecting mental illness and social stress in hospital workers treating COVID-19: Paradoxical distress during pandemic era
2021.03.25 Thu Press Release Horizontal transmission can cause severe and persistent eye inflammation
2021.03.19 Fri Press Release Development of Methods for Convergent Synthesis of Chloroalkene Dipeptide Isosteres and Its Application
2021.03.18 Thu Press Release A missense variant in NUF2, a component of the kinetochore NDC80 complex, causes impaired chromosome segregation and aneuploidy associated with microcephaly and short stature
2021.03.18 Thu Press Release Sparsely methylated mitochondrial cell free DNA released from cardiomyocytes contributes to systemic inflammatory response accompanied by atrial fibrillation
2021.03.16 Tue Press Release Risk factors for distant metastasis in locoregionally controlled oral squamous cell carcinoma: a retrospective study
2021.03.12 Fri Press Release A new polarized fluorescent probe for revealing architectural dynamics of living cells
2021.03.08 Mon News TMDU is ranked 1st for dentistry and 4th for medicine in Japan, and 5th for dentistry and 114th for medicine in the world from QS World University Rankings 2021 by Subject!
2021.03.01 Mon Press Release Common Origin of the Cerebellar Dual Somatotopic Areas Revealed by Tracking Embryonic Purkinje Cell Clusters with Birthdate Tagging
2021.02.05 Fri Press Release Keep it Moving: How a Biomaterial Mobility May Revolutionize Immunomodulation
2020.12.09 Wed Press Release Dual effect of molecular mobility and functional groups of polyrotaxane surfaces on the fate of mesenchymal stem cells
2020.11.30 Mon Press Release Fluctuation in radioresponse of HeLa cells during the cell cycle evaluated based on micronucleus frequency
2020.11.25 Wed Press Release A subtle change in the DNA may predispose to polyneuropathy after gut infection
2020.11.24 Tue Press Release Ultrasonography Shows Age-related Changes and Related Factors in the Tongue and Suprahyoid Muscles
2020.11.24 Tue Press Release Improving the Efficacy of EGFR Inhibitors by Topical Treatment of Cutaneous Squamous Cell Carcinoma with miR-634 Ointment
2020.11.13 Fri Press Release WNK regulates Wnt signalling and β-Catenin levels by interfering with the interaction between β-Catenin and GID
2020.11.10 Tue Press Release Fujitsu and Tokyo Medical and Dental University Leverage World’s Fastest Supercomputer to Perform Cancer Gene Network Analysis in Less than a Day
2020.10.29 Thu Press Release TMDU is ranked #79 for Clinical & Health in THE World University Rankings by Subject 2021!
2020.10.28 Wed Press Release A missense mutation in the RSRSP stretch of Rbm20 causes dilated cardiomyopathy and atrial fibrillation in mice
2020.10.19 Mon Press Release HFD-induced hepatic lipid accumulation and inflammation are decreased in Factor D deficient mouse
2020.10.16 Fri Press Release Hinder Handing the Message– Stopping Tumors from Creating New Blood Vessels
2020.09.08 Tue Press Release IRF2 maintains the stemness of colonic stem cells by limiting physiological stress from interferon
2020.08.27 Thu Press Release Increasing the Effectiveness of Cancer Treatments: Anti-PD-L1 Immunotherapy
2020.07.27 Mon Press Release Targeting all transforming growth factor-β isoforms with an Fc chimeric receptor impairs tumor growth and angiogenesis of oral squamous cell cancer
2020.07.20 Mon Press Release The key royal jelly component 10-hydroxy-2-decenoic acid protects against bone loss via FFAR4
2020.07.14 Tue Press Release Shigella prevents infected cells from sacrificing themselves for the greater good
2020.06.30 Tue Press Release Joint Research Coronavirus Task Force Established to Promote Research and Development of COVID-19 Vaccine for Mucosal Immunity Based on Genetic Findings of the Novel Coronavirus Disease
2020.06.17 Wed Press Release Hollow fiber-combined glucose-responsive gel technology as an in vivo electronics-free insulin delivery system
2020.06.02 Tue Press Release In vitro neo-genesis of tendon-like tissue by combination of Mohawk and a three-dimensional cyclic mechanical stretch culture system
2020.06.01 Mon Press Release Lin28a/let-7 Pathway Modulates the Hox Code via Polycomb Regulation during Axial Patterning in Vertebrates
2020.06.01 Mon Press Release “Opening of an open-laboratory for research into next generation ventilators, and for evaluation and research, etc. of new ventilator types, with a view towards responding to the surge in numbers of novel coronavirus patients”
2020.05.25 Mon Press Release Characterization of radioresistant epithelial stem cell heterogeneity in the damaged mouse intestine
2020.05.13 Wed Press Release Glioma stem cell (GSC)‐derived autoschizis‐like products confer GSC niche properties involving M1‐like tumor‐associated macrophages
2020.05.07 Thu Press Release Analysis of the mouse Y chromosome by single molecule sequencing with Y chromosome enrichment.
2020.04.20 Mon Press Release miR-1293, a candidate for miRNA-based cancer therapeutics, simultaneously targets BRD4 and the DNA repair pathway
2020.04.17 Fri Press Release Overlapping but asymmetrical relationships between schizophrenia and autism revealed by brain connectivity
2020.04.02 Thu Press Release Tolerogenic properties of CD206+ macrophages appeared in the sublingual mucosa after repeated antigen-painting
2020.03.06 Fri Press Release TMDU is ranked 1st (Dentistry in Japan) and 4th (Medicine in Japan) in QS World University Rankings 2020 by Subject!
2020.03.02 Mon Press Release Effectiveness of using an educational video simulating the anatomical mechanism of shaking and smothering in a home visit program to prevent self reported infant abuse
2020.02.12 Wed Press Release A Joint Clinical Research Collaboration among Tokyo Medical and Dental University (TMDU), ACT Genomics , and ACTmed Seeks to Investigate the Cancer Genomic Landscape of Japanese Population
2020.01.31 Fri Press Release Estradiol/GPER affects the integrity of mammary duct-like structures in vitro
2020.01.23 Thu Press Release Timing of Brain Cell Death Uncovers a New Target for Alzheimer’s Treatment
2020.01.15 Wed Press Release Cannabidiol suppresses the induction of neoplastic osteoclasts – Aiming to develop new therapeutic agents against cancer-induced bone destruction—
2020.01.08 Wed Press Release Development of anticancer drug with tumor-suppressive <i>miR-634</i> as a drug seed for the nucleic acid therapeutics
2020.01.08 Wed Press Release Vpu Protein of Simian Immunodeficiency Virus Isolated from a Monkey Species Living in Africa Overcomes Function of Human Antiviral Protein BST-2
2019.12.27 Fri Press Release "Elucidating the relationship of oral nutrition to systemic health" -Oral and gut microbiome are key: prospects for improvement of medical care through dysphagia rehabilitation-
2019.12.23 Mon Press Release "Intracellular localization of claudin-1 at the invasive front of tongue cancer is associated with lymph node metastasis”
2019.12.02 Mon Press Release TMDU is ranked #74 for Clinical, Pre-clinical & Health in THE World University Rankings by Subject 2020!
2019.11.27 Wed Press Release Temporospatial sonic hedgehog signalling is essential for neural crest-dependent patterning of the intrinsic tongue musculature
2019.11.06 Wed Press Release Bile duct biomarker? Protein found to pinpoint patients with a lethal cancer
2019.11.01 Fri Press Release A Nice Reactive Ring to It: New Synthetic Pathways for Diverse Aromatic Compounds
2019.10.21 Mon Press Release “Instant Liver, Just Add Water”? Not Quite, but a Better Way to Grow Multiple Organs
2019.09.24 Tue Press Release Comparative analysis demonstrates cell type-specific conservation of SOX9 targets between mouse and chicken
2019.09.11 Wed Press Release Stem cell competition offers a mechanism for skin youthfulness and ageing
2019.07.30 Tue Press Release Involvement of N-type Ca2+ channel in microglial activation and its implications to aging-induced exaggerated cytokine response
2019.07.24 Wed Press Release "HDO-antimiR represents a new weapon in the fight against microRNA-related disease"
2019.07.04 Thu Press Release Enhancement of Motor Function Recovery After Spinal Cord Injury in Mice by Delivery of Brain Derived Neurotrophic Factor mRNA
2019.07.03 Wed Press Release Fibroblast growth factor signals regulate transforming growth factor‐β‐induced endothelial‐to‐myofibroblast transition of tumor endothelial cells via Elk1
2019.07.01 Mon Press Release Tolvaptan activates the Nrf2/HO-1 antioxidant pathway through PERK phosphorylation
2019.06.25 Tue Press Release Blockade of microglial Cav1.2 Ca2+ channel exacerbates the symptoms in a Parkinson’s disease model
2019.06.13 Thu Press Release Reciprocal cortical activation patterns during incisal and molar biting correlated with bite force levels: an fMRI study.
2019.06.05 Wed Press Release MRTF A regulates proliferation and survival properties of pro atherogenic macrophages
2019.05.31 Fri Press Release Modeling Steatohepatitis in Human with Pluripotent Stem Cell-Derived Organoids
2019.05.29 Wed Press Release Antibacterial activity of lysozyme-chitosan oligosaccharide conjugates (LYZOX) against Pseudomonas aeruginosa, Acinetobacter baumannii and Methicillin-resistant Staphylococcus aureus
2019.04.23 Tue Press Release Synthesis of Alkynyl Sulfides by Copper-Catalyzed Thiolation of Terminal Alkynes Using Thiosulfonates
2019.04.16 Tue Press Release Silencing of PD-L2/B7-DC by Topical Application of Small Interfering RNA Inhibits Elicitation of Contact Hypersensitivity
2019.04.12 Fri Press Release Development of a NanoBRET-based Sensitive Screening Method for CXCR4 Ligands
2019.04.10 Wed Press Release Impact of novel NS5A resistance-associated substitutions of hepatitis C virus detected in treatment-experienced patients
2019.03.19 Tue Press Release Loss of Fibrocystin Promotes Interleukin-8-Dependent Proliferation and CTGF Production of Biliary Epithelium
2019.03.15 Fri Press Release "How does estrogen protect bones? Unraveling a pathway to menopausal bone loss"
2019.03.11 Mon Press Release TMDU is ranked 1st (Dentistry in Japan) and 3rd (Medicine in Japan) in QS World University Rankings 2019 by Subject!
2019.03.07 Thu Press Release A facile preparation of functional cycloalkynes via an azide-to-cycloalkyne switching approach
2019.02.26 Tue Press Release Treatment of intervertebral disk disease by administration of messenger RNA encoding a cartilage-anabolic transcription factor
2019.02.15 Fri Press Release LIM homeobox 2 promotes interaction between human iPS-derived hepatic progenitors and iPS-derived hepatic stellate-like cells
2019.02.06 Wed Press Release "Shedding Light on Zebrafish Daily Rhythms: Clock Gene Functions Revealed"
2019.02.05 Tue Press Release Interleukin-13 receptor α2 is a novel marker and potential therapeutic target for human melanoma
2019.01.31 Thu Press Release "Crunching the Data: New Liver Cancer Subtypes Revealed Immunologically"
2019.01.24 Thu Press Release Induced Proton Perturbation for Sensitive and Selective Detection of Tight Junction Breakdown
2019.01.17 Thu Press Release ”Killer Blows? Knockout Study of Pair of Mouse MicroRNA Provides Cancer Insight”
2018.12.20 Thu Press Release Short-term prognosis of emergently hospitalized dialysis-independent chronic kidney disease patients: a nationwide retrospective cohort study in Japan
2018.12.18 Tue Press Release Loss of KDM6A characterizes a poor prognostic subtype of human pancreatic cancer and potentiates HDAC inhibitor lethality
2018.12.14 Fri Press Release "Stop that clot! Quantitative assessment of the blood coagulation cascade"
2018.12.13 Thu Press Release Ubiquitin D is up-regulated by synergy of Notch signaling and TNF-α in the inflamed intestinal epithelia of IBD patients.
2018.12.07 Fri Press Release "Undiplomatic Immunity: Mutation Causing Arterial Autoimmune Disease Revealed"
2018.12.07 Fri Press Release "Faulty sensing: cellular energy sensor linked to the progression of chronic kidney disease"
2018.12.04 Tue Press Release Asymmetric dimethylation at histone H3 arginine 2 by PRMT6 in gastric cancer progression
2018.11.08 Thu Press Release "Small populations of normal cells affect immunity in patients with XLP1"
2018.10.29 Mon Press Release "Virus Production Boosted in Cells to Generate More Vectors for Gene Transfer"
2018.10.11 Thu Press Release "Early Changes to Synapse Gene Regulation May Cause Alzheimer’s Disease"
2018.08.24 Fri Press Release Combinatorial CRISPR/Cas9 approach to elucidate a far-upstream enhancer complex for tissue-specific Sox9 expression
2018.08.17 Fri Press Release Downregulated Pancreatic Beta Cell Genes Indicate Poor Prognosis in Patients With Pancreatic Neuroendocrine Neoplasms.
2018.08.16 Thu Press Release "Controlling STAT3 may provide new therapy for chronic active Epstein-Barr virus infection, a chemotherapy-resistant T- or NK-cell neoplasm"
2018.08.06 Mon Press Release Integrated analysis of human genetic association study and mouse transcriptome suggests <i>LBH</i> and <i>SHF</i> genes as novel susceptible genes for amyloid-beta accumulation in Alzheimer's disease.
2018.07.19 Thu Press Release Histamine Released From Skin-Infiltrating Basophils but Not Mast Cells Is Crucial for Acquired Tick Resistance in Mice.
2018.06.20 Wed Press Release "Of Hearts and Giants: Moving a Cardiac Regulatory Protein to the Right Place"
2018.06.19 Tue Press Release Transient Protection of Organic Azides from Click Reactions with Alkynes by Phosphazide Formation.
2018.06.19 Tue Press Release Angubindin-1 opens the blood-brain barrier in vivo for delivery of antisense oligonucleotide to the central nervous system.
2018.06.05 Tue Press Release Hematopoietic stem cell transplantation for progressive combined immunodeficiency and lymphoproliferation in patients with activated phosphatidylinositol-3-OH kinase δ syndrome type 1.
2018.05.22 Tue Press Release Staudinger reaction using 2,6-dichlorophenyl azide derivatives for robust aza-ylide formation applicable to bioconjugation in living cells
2018.05.07 Mon Press Release Region-specific deletions of the glutamate transporter GLT1 differentially affect nerve injury-induced neuropathic pain in mice.
2018.05.07 Mon Press Release Stable lines and clones of long-term proliferating normal, genetically unmodified murine common lymphoid progenitors
2018.04.26 Thu Press Release Overexpression of heart-specific small subunit of myosin light chain phosphatase results in heart failure and conduction disturbance.
2018.04.17 Tue Press Release CD22-Binding Synthetic Sialosides Regulate B Lymphocyte Proliferation Through CD22 Ligand-Dependent and Independent Pathways, and Enhance Antibody Production in Mice.
2018.04.13 Fri Press Release AKAPs-PKA disruptors increase AQP2 activity independently of vasopressin in a model of nephrogenic diabetes insipidus
2018.04.04 Wed Press Release IMSindel: An accurate intermediate-size indel detection tool incorporating de novo assembly and gapped global-local alignment with split read analysis
2018.04.03 Tue Press Release Ovarian cancer therapeutic potential of glutamine depletion based on GS expression.
2018.03.19 Mon Press Release "Forming and resorbing bones: metastasizing cancer cells modify bone remodeling with small RNA secretion"
2018.03.13 Tue Press Release "Potential RNA Markers of Abnormal Heart Rhythms Identified in Circulating Blood"
2018.03.06 Tue Press Release "Technique Allows Live Imaging of “Ubiquitous” Player in Cellular Housekeeping"
2018.03.06 Tue Press Release "Epigenetic Modulation of Fgf21 Gene in Early-Life Ameliorates Adulthood Diet-Induced Obesity "
2018.02.23 Fri Press Release "Insights into familial middle-age dementia suggest new avenues for treatment"
2018.01.16 Tue Press Release Microneedle‐Array Patch Fabricated with Enzyme‐Free Polymeric Components Capable of On‐Demand Insulin Delivery
2018.01.12 Fri Press Release "Protein YAP in Early Life Influences Adult Spinocerebellar Ataxia Pathology"
2017.12.12 Tue Press Release "Role of Transcriptional Co-factor in Inflammation Hints at Possible Inflammatory Bowel Disease Treatment"
2017.12.08 Fri Press Release "Monitoring Thyroid Response: Biomarker May Predict Graves’ Disease Relapse"
2017.10.20 Fri Press Release "RANKL expressed by osteocytes has an important role in orthodontic tooth movement"
2017.10.18 Wed Press Release ”Superior vena cava (or SVC) - derived atrial fibrillation attributes to both clinical and genetic factors”
2017.08.01 Tue Press Release "Gene-Regulatory Factors Shown to Improve Pancreatic Cancer Response to Chemotherapy"
2017.07.10 Mon Press Release "Reduced mastication results in the impairment of memory and learning function"
2017.06.13 Tue Press Release "Discovery of Human Blood Cell Destinies Revises Knowledge of Immune Cell Development"
2016.12.27 Tue Press Release "Alzheimer’s Disease Pathway Identification Enables Development of Novel Preclinical Therapy"
2016.12.16 Fri Press Release "Degrader of Proteins Required for the Origin of Early Cancerous Lesions"
2016.12.14 Wed Press Release "Breakthrough in Hepatitis Research as New Infected Cell Models are Developed"
2016.11.24 Thu Press Release ”Role for Autophagic Cellular Degradation Process in Maintaining Genomic Stability”
2016.11.22 Tue Press Release "How Cell Populations Weed Out “Loser” Cells to Maintain Vitality is Revealed"
2016.11.22 Tue Press Release ”Novel Type of Cell Death in Huntington’s Disease May Lead to Effective New Therapies”
2016.10.31 Mon Press Release “Advancing Our Understanding of How the Disease Lupus is prevented in healthy individuals”
2016.10.05 Wed Press Release “Breakthrough for Bone Regeneration via Double-cell-layered Tissue Engineering Technique”
2016.08.23 Tue Press Release “Injected Mix of Bone-augmenting Agents Causes New Bone Growth in Mouse Jaws”
2016.06.07 Tue Press Release “World's First Measurement and Visualization of Cardiac Activity Using MR Sensors”
2016.02.16 Tue Press Release “Periodic injections of synovial stem cells inhibit osteoarthritis progression in the knee”
2016.02.01 Mon Press Release “Synthetic polymer-based elucidation of survival strategies of cancer stem cells”
2015.11.26 Thu Press Release Tokyo Medical and Dental University (TMDU) becomes the first university in Japan to establish an international joint degree (JD) program, and has concluded an agreement with University of Chile and its associated hospital.
2015.11.26 Thu Press Release Tokyo Medical and Dental University (TMDU) becomes the first university in Japan allowed to establish an international joint degree (JD) program having an agreement with Chulalongkorn University.
2015.09.29 Tue Press Release Tokyo Medical and Dental University to establish an INCJ-backed venture company, Rena Therapeutics Inc.
2015.08.11 Tue Press Release “DNA/RNA Heteroduplex oligonucleotide: the third class oligonucleotides”
2014.08.18 Mon Press Release “Transplanting Cultured Small Intestinal Epithelial Stem Cells onto Colon”
2014.04.23 Wed Press Release “Discovery of the molecule Sox17 to maintain the hematopoietic stem cell at embryonic stages”
2013.09.13 Fri Press Release “Discovery of a novel function of dendritic cells to fine-tune excessive immune responses”
2013.04.26 Fri Press Release “Discovery of a novel source of dendritic cells, the control tower of the immune system”
2013.02.22 Fri Press Release “Identification of a novel mechanism by which allergic inflammation is dampened”
2012.10.11 Thu Press Release “3D MRI Analyses Clarify that Pathologic Myopia is Caused by Eye Globe Deformity”
2012.03.12 Mon Press Release “Functional Engraftment of Colon Epithelium Expanded In Vitro from a Single Adult Lgr5+ Stem Cell”
2012.02.27 Mon Event “Identification of a key regulator molecule that prevents neutrophil over-activation”
2011.09.28 Wed Press Release “A Single-Use, Centrifugal Type Assist Heart with Excellent Durability and Biocompatibility”
2011.02.04 Fri Press Release “Hair Follicle Stem Cells Provide a Functional Niche for Melanocyte Stem Cells”
2010.05.04 Tue Event “Impairment of DNA-repair by mutant Huntingtin is a major cause of neurodegenerative pathology in Huntington’s disease.”
2010.04.12 Mon Event “Identification of the gene regulating the development of T cells that cause autoimmune diseases”
