業績
原著論文 (2007-2010年）
1. Sakota D and Takatani S. Photon－Cell Interactive Monte Carlo “pciMC” model based on the geometric optics theory for photon migration in blood by incorporating both extra- and intra- cellular pathways. J Biomed Optics (accepted for publication will appear in November-December issue of 2010).
2. Ugaki S, Honjo O, Nakakura M, Douguchi T, Itagaki A, Yokoyama N, Ohuchi K, Takatani S, and Sano S. Transfusion-Free Neonatal Cardiopulmonary Bypass Using a TinyPump, Annals of Thoracic Surgery, (accepted for publication and will appear in November issue of 2010)
3. Kitao T, Ando Y, Yoshikawa M, Kobayashi M, Kimura T, Ohsawa H, Machida S, Yokoyama N, Sakota D, Konno T, Ishihara K, Takatani S. In Vivo Evaluation of the ‘TinyPump’ for Pediatric Left Ventricular Assist Device Application. Artif Organs (Accepted for publication).
4. Yokoyama Y, Kawaguchi O, Shinshi T, Steinseifer U, Takatani S. A new Pulse Duplicator with a Passive Fill Ventricle for Analysis of Cardiac Dynamics. J Artif Organs (accepted for publication).
5. Yokoyama Y, Kawaguchi O, Kitao T, Kimura T, Steinseifer U, and Takatani S. Prediction of the external work of the native heart from the dynamic H-Q curves of the rotary blood pumps during left heart bypass. Artif Organs 2010; 34(9): 766-777.
6. Nagaoka E, Someya T, Kitao T, Kimura T, Ushiyama T, Hijikata W, Shinshi T, Arai H, Takatani S. Development of a disposable magnetically levitated centrifugal blood pump (MedTech Dispo) intended for bridge-to-bridge applications -Two-week in vivo evaluation. Artif Organs 2010; 34(9): 778-783.
7. Hijikata W, Sobajima H, Shinshi T, Nagamine Y, Wada S, Takatani S, and Shimokohbe A. Disposable MagLev Centrifugal Blood Pump Utilizing a Cone-Shaped Impeller. Artif Organs 2010; 34(8): 669-677.
8. Honjo O, Merklinger SL, Poe JB, Guergurian AM, Alghandi AA, Takatani S, and Van Arsdell GS. Mechanical cavopulmonary assist maintains pulmonary and cerebral blood flow in a piglet model of a bidirectional cavopulmonary shunt with high pulmonary vascular resistance. The Journal of Thoracic and Cardiovascular Surgery 2009; 137(2): 355-361.
9. Sakota D, Sakamoto R, Yokoyama N, Kobayashi M, and Takatani S. Glucose Depletion Enhances Sensitivity to Shear Stress-induced Mechanical Damage in Red Blood Cells by Rotary Blood Pumps. Artif Organs 2009; 33(9):733-739.
10. Someya T, Kobayashi M, Waguri S, Ushiyama T, Nagaoka E, Hijikata W, Shinshi T, Arai H, and Takatani S. Development of a Disposable Maglev Centrifugal Blood Pump Intended for One- Month Support in Bridge-to-Bridge Applications: In Vitro and Initial In Vivo Evaluation. Artif Organs 2009; 33(9):704-713.
11. Yasuda T, Saito T, Kihara T, Takatani S, Funakubo A. Development of a reflected optical fiber system for measuring oxygen saturation in an integrated artificial heart-lung system. Artif Organs 2008; 32(3): 229-234.
12. Hijikata W, Shinshi T, Asama J, Li L, Hoshi H, Takatani S, Shimokohbe A. A magnetically levitated centrifugal blood pump with a simple-structured disposable pump head. Artif Organs 2008; 32(7): 531-540.
13. Sakota D, Sakamoto R, Sobajima H, Yokoyama N, Waguri S,. Ohuchi K, and Takatani S. Mechanical damage of red blood cells by rotary blood pumps: Selective destruction of aged red cells and sub-hemolytic trauma. Artif Organs 2008; 32(10): 785-791.
14. Pai CN, Shinshi T, Asama J, Takatani S, Shimokohbe A. Development of a compact, centrifugal rotary blood pump with magnetically levitated impeller using a titanium housing. Journal of Advanced Mechanical Design, Systems and Manufacturing 2008; 2(3): 343-355.
15. Sakota D, Sakamoto R, Sobajima R, Yokoyama N, Yokoyama Y, Waguri S, Ohuchi K, and Takatani S. Time-resolved optical spectroscopic quantification of the red blood cell damage cause by the cardiovascular devices. Proc of SPIE 2008; 6864: 10-1,8.
16. Kakino S, Takagi Y, Takatani S. Absolute transmitted light plethysmography for assessment of dental pulp vitality through quantification of pulp chamber hematocrit by a three-layer model. Journal of Biomedical Optics 13(5), 054023 (September/October 2008).
17. 大内克洋、叶 学、三井和幸、高谷節雄。心筋細胞電気機械モデルによる電気機械帰還現象と機械的負荷低減効果のシミュレーション解析。ライフサポート、2008．（最終論文 受理日2008年8月6日）
18. Lee I, Kobayashi K, Sun HY, Takatani S, Zhong LG. Biomembrane mimetic polymer poly(2- methacryloyloxyethyl Phosphorylcholine-co-n-butyl methacrylate) at the interface of polyurethane surfaces. J Biomed Mater Res 2007; 82A: 316-322.
19. Asama J, Shinshi T, Hoshi H, Takatani S, and Shimokohbe A, Dynamic Characteristics of a Magnetically-Levitated Impeller in a Centrifugal Blood Pump, Artif Organs 2007; 31(4): 301-311.
20. Watanabe N, Sakota D, Ohuchi K, and Takatani S. Deformability of red blood cells and its relation to blood trauma in rotary blood pumps. Artif Organs 2007; 31(5): 352-358.
21. Watanabe N, Arakawa Y, Sou A, Kataoka H, Ohuchi K, Fujimoto T, Takatani S. Deformability of human red blood cells exposed to a uniform shear stress as measured by a cyclically reversing shear flow generator. Physiological Measurement 2007; 28: 531-545.
22. Ohuchi K, Hoshi H, Watanbe N, Kido K, Yokoyama Y, Asama J, Shinshi T, Shimokohbe A, Yoshikawa M, Takatani S. Mechanical circulatory support systems at Tokyo Medical and Dental University. Biocybernetics and Biomedical Engineering 2007; 27(1/2): 161-167.
23. Ohuchi K, Hoshi H, Iwasaki Y, Ishihara K, Yoshikawa M, Ugaki S, Ishino K, Osaki S, Kotani Y, Sano S, Takatani S. Feasibility of a tiny centrifugal blood pump (TinyPump) for pediatric extracorporeal circulatory support. Artif Organs 2007; 31(5): 408-412.
24. Yokoyama N, Suzuki M, Hoshi H, Ohuchi K, Fujimoto T, Takatani S. Feasibility of a TinyPump System for Pediatric CPB, ECMO and Circulatory Assistance: Hydrodynamic Performances of the Modified Pump Housing for Implantable TinyPump. ASAIO J 2007 Nov-Dec; 53: 742-746.
25. Ugaki S, Ishino K, Osaki S, Kotani Y, Honjo O, Hoshi H, Yokoyama N, Ohuchi K, Takatani S, Sano S. Efficacy of a miniature centrifugal rotary pump (TinyPump) for transfusion-free cardiopulmonary bypass in neonatal piglets. ASAIO J 2007 Nov-Dec; 53: 675-679
26. Honjo O, Merklinger SL, Poe J, Gueguerian AM, Alghamdi AA, Takatani S, Arsdell GS Van. A novel mechanical lung assist system sustains primary bidirectional cavopulmonary shunt circulation in pigs. ASAIO J 2007 Nov-Dec; 53: 720-724.
27. Kobayashi A, Miyake H, Hattori H, Kuwana R, Hiruma Y, Nakahama K, Ichinose S, Ota M, Nakamura M, Takeda S, Morita I. In vitro formation of capillary networks using optical lithographic techniques. Biochemical and Biophysical Research Communications 2007; 358(3):692-7.
成書・総説・トピックス
1. 小林真理子、高谷節雄、小児用小型遠心血液ポンプの開発、東京医科歯科大学生体材料工学研究所年報 42巻、44－47.
2. 高谷節雄、次世代人工心臓の研究開発、東京医科歯科大学御茶ノ水医科同窓会・会報、2009 12/11 NO.244 46-47.
3. Takatani S. In remembrance of Dr. Tetsuzo Akutsu: a man who started artificial heart research. J Artif Organs 2008; 11: 1-3.
4. 高谷節雄 故阿久津哲造博士を偲んで。人工臓器 ３７巻１号４－７、２００８年。
5. Takatani S. Guest Editorial; Progress of rotary blood pump: Presidential address, International Society for Rotary Blood Pump 2006, Leuven, Belgium, Artif Organs 2007;31(5):329-344.
6. Tatsumi E, Nakatani T, Imachi K, Umezu M, Kyo S, Sase K, Takatani S, Matsuda H. Domestic and foreign trends in the prevalence of heart failure and the necessity of next generation artificial hearts: a survey by the working group on establishment of assessment guidelines for next-generation artificial heart system. J Artif Organs 2007; 10: 187-194.
7. 巽 英介、中谷武嗣、井街 宏、梅津光生、許 俊鋭、佐藤一洋、高谷節雄、松田 輝、国内外の心不全の動向と我が国における次世代型人工心臓の必要性について：次世代型高機能人工心臓審査ガイドラインワーキンググループからの提言。人工臓器2007年36巻1号6-12。
8. 高谷節雄。人工心臓の世界の動向。第5回生活支援工学系学会連合大会（第23回ライフサポート学会大会）論文集：ｐ２０．
1. Sakota D and Takatani S. Photon－Cell Interactive Monte Carlo “pciMC” model based on the geometric optics theory for photon migration in blood by incorporating both extra- and intra- cellular pathways. J Biomed Optics (accepted for publication will appear in November-December issue of 2010).
2. Ugaki S, Honjo O, Nakakura M, Douguchi T, Itagaki A, Yokoyama N, Ohuchi K, Takatani S, and Sano S. Transfusion-Free Neonatal Cardiopulmonary Bypass Using a TinyPump, Annals of Thoracic Surgery, (accepted for publication and will appear in November issue of 2010)
3. Kitao T, Ando Y, Yoshikawa M, Kobayashi M, Kimura T, Ohsawa H, Machida S, Yokoyama N, Sakota D, Konno T, Ishihara K, Takatani S. In Vivo Evaluation of the ‘TinyPump’ for Pediatric Left Ventricular Assist Device Application. Artif Organs (Accepted for publication).
4. Yokoyama Y, Kawaguchi O, Shinshi T, Steinseifer U, Takatani S. A new Pulse Duplicator with a Passive Fill Ventricle for Analysis of Cardiac Dynamics. J Artif Organs (accepted for publication).
5. Yokoyama Y, Kawaguchi O, Kitao T, Kimura T, Steinseifer U, and Takatani S. Prediction of the external work of the native heart from the dynamic H-Q curves of the rotary blood pumps during left heart bypass. Artif Organs 2010; 34(9): 766-777.
6. Nagaoka E, Someya T, Kitao T, Kimura T, Ushiyama T, Hijikata W, Shinshi T, Arai H, Takatani S. Development of a disposable magnetically levitated centrifugal blood pump (MedTech Dispo) intended for bridge-to-bridge applications -Two-week in vivo evaluation. Artif Organs 2010; 34(9): 778-783.
7. Hijikata W, Sobajima H, Shinshi T, Nagamine Y, Wada S, Takatani S, and Shimokohbe A. Disposable MagLev Centrifugal Blood Pump Utilizing a Cone-Shaped Impeller. Artif Organs 2010; 34(8): 669-677.
8. Honjo O, Merklinger SL, Poe JB, Guergurian AM, Alghandi AA, Takatani S, and Van Arsdell GS. Mechanical cavopulmonary assist maintains pulmonary and cerebral blood flow in a piglet model of a bidirectional cavopulmonary shunt with high pulmonary vascular resistance. The Journal of Thoracic and Cardiovascular Surgery 2009; 137(2): 355-361.
9. Sakota D, Sakamoto R, Yokoyama N, Kobayashi M, and Takatani S. Glucose Depletion Enhances Sensitivity to Shear Stress-induced Mechanical Damage in Red Blood Cells by Rotary Blood Pumps. Artif Organs 2009; 33(9):733-739.
10. Someya T, Kobayashi M, Waguri S, Ushiyama T, Nagaoka E, Hijikata W, Shinshi T, Arai H, and Takatani S. Development of a Disposable Maglev Centrifugal Blood Pump Intended for One- Month Support in Bridge-to-Bridge Applications: In Vitro and Initial In Vivo Evaluation. Artif Organs 2009; 33(9):704-713.
11. Yasuda T, Saito T, Kihara T, Takatani S, Funakubo A. Development of a reflected optical fiber system for measuring oxygen saturation in an integrated artificial heart-lung system. Artif Organs 2008; 32(3): 229-234.
12. Hijikata W, Shinshi T, Asama J, Li L, Hoshi H, Takatani S, Shimokohbe A. A magnetically levitated centrifugal blood pump with a simple-structured disposable pump head. Artif Organs 2008; 32(7): 531-540.
13. Sakota D, Sakamoto R, Sobajima H, Yokoyama N, Waguri S,. Ohuchi K, and Takatani S. Mechanical damage of red blood cells by rotary blood pumps: Selective destruction of aged red cells and sub-hemolytic trauma. Artif Organs 2008; 32(10): 785-791.
14. Pai CN, Shinshi T, Asama J, Takatani S, Shimokohbe A. Development of a compact, centrifugal rotary blood pump with magnetically levitated impeller using a titanium housing. Journal of Advanced Mechanical Design, Systems and Manufacturing 2008; 2(3): 343-355.
15. Sakota D, Sakamoto R, Sobajima R, Yokoyama N, Yokoyama Y, Waguri S, Ohuchi K, and Takatani S. Time-resolved optical spectroscopic quantification of the red blood cell damage cause by the cardiovascular devices. Proc of SPIE 2008; 6864: 10-1,8.
16. Kakino S, Takagi Y, Takatani S. Absolute transmitted light plethysmography for assessment of dental pulp vitality through quantification of pulp chamber hematocrit by a three-layer model. Journal of Biomedical Optics 13(5), 054023 (September/October 2008).
17. 大内克洋、叶 学、三井和幸、高谷節雄。心筋細胞電気機械モデルによる電気機械帰還現象と機械的負荷低減効果のシミュレーション解析。ライフサポート、2008．（最終論文 受理日2008年8月6日）
18. Lee I, Kobayashi K, Sun HY, Takatani S, Zhong LG. Biomembrane mimetic polymer poly(2- methacryloyloxyethyl Phosphorylcholine-co-n-butyl methacrylate) at the interface of polyurethane surfaces. J Biomed Mater Res 2007; 82A: 316-322.
19. Asama J, Shinshi T, Hoshi H, Takatani S, and Shimokohbe A, Dynamic Characteristics of a Magnetically-Levitated Impeller in a Centrifugal Blood Pump, Artif Organs 2007; 31(4): 301-311.
20. Watanabe N, Sakota D, Ohuchi K, and Takatani S. Deformability of red blood cells and its relation to blood trauma in rotary blood pumps. Artif Organs 2007; 31(5): 352-358.
21. Watanabe N, Arakawa Y, Sou A, Kataoka H, Ohuchi K, Fujimoto T, Takatani S. Deformability of human red blood cells exposed to a uniform shear stress as measured by a cyclically reversing shear flow generator. Physiological Measurement 2007; 28: 531-545.
22. Ohuchi K, Hoshi H, Watanbe N, Kido K, Yokoyama Y, Asama J, Shinshi T, Shimokohbe A, Yoshikawa M, Takatani S. Mechanical circulatory support systems at Tokyo Medical and Dental University. Biocybernetics and Biomedical Engineering 2007; 27(1/2): 161-167.
23. Ohuchi K, Hoshi H, Iwasaki Y, Ishihara K, Yoshikawa M, Ugaki S, Ishino K, Osaki S, Kotani Y, Sano S, Takatani S. Feasibility of a tiny centrifugal blood pump (TinyPump) for pediatric extracorporeal circulatory support. Artif Organs 2007; 31(5): 408-412.
24. Yokoyama N, Suzuki M, Hoshi H, Ohuchi K, Fujimoto T, Takatani S. Feasibility of a TinyPump System for Pediatric CPB, ECMO and Circulatory Assistance: Hydrodynamic Performances of the Modified Pump Housing for Implantable TinyPump. ASAIO J 2007 Nov-Dec; 53: 742-746.
25. Ugaki S, Ishino K, Osaki S, Kotani Y, Honjo O, Hoshi H, Yokoyama N, Ohuchi K, Takatani S, Sano S. Efficacy of a miniature centrifugal rotary pump (TinyPump) for transfusion-free cardiopulmonary bypass in neonatal piglets. ASAIO J 2007 Nov-Dec; 53: 675-679
26. Honjo O, Merklinger SL, Poe J, Gueguerian AM, Alghamdi AA, Takatani S, Arsdell GS Van. A novel mechanical lung assist system sustains primary bidirectional cavopulmonary shunt circulation in pigs. ASAIO J 2007 Nov-Dec; 53: 720-724.
27. Kobayashi A, Miyake H, Hattori H, Kuwana R, Hiruma Y, Nakahama K, Ichinose S, Ota M, Nakamura M, Takeda S, Morita I. In vitro formation of capillary networks using optical lithographic techniques. Biochemical and Biophysical Research Communications 2007; 358(3):692-7.
成書・総説・トピックス
1. 小林真理子、高谷節雄、小児用小型遠心血液ポンプの開発、東京医科歯科大学生体材料工学研究所年報 42巻、44－47.
2. 高谷節雄、次世代人工心臓の研究開発、東京医科歯科大学御茶ノ水医科同窓会・会報、2009 12/11 NO.244 46-47.
3. Takatani S. In remembrance of Dr. Tetsuzo Akutsu: a man who started artificial heart research. J Artif Organs 2008; 11: 1-3.
4. 高谷節雄 故阿久津哲造博士を偲んで。人工臓器 ３７巻１号４－７、２００８年。
5. Takatani S. Guest Editorial; Progress of rotary blood pump: Presidential address, International Society for Rotary Blood Pump 2006, Leuven, Belgium, Artif Organs 2007;31(5):329-344.
6. Tatsumi E, Nakatani T, Imachi K, Umezu M, Kyo S, Sase K, Takatani S, Matsuda H. Domestic and foreign trends in the prevalence of heart failure and the necessity of next generation artificial hearts: a survey by the working group on establishment of assessment guidelines for next-generation artificial heart system. J Artif Organs 2007; 10: 187-194.
7. 巽 英介、中谷武嗣、井街 宏、梅津光生、許 俊鋭、佐藤一洋、高谷節雄、松田 輝、国内外の心不全の動向と我が国における次世代型人工心臓の必要性について：次世代型高機能人工心臓審査ガイドラインワーキンググループからの提言。人工臓器2007年36巻1号6-12。
8. 高谷節雄。人工心臓の世界の動向。第5回生活支援工学系学会連合大会（第23回ライフサポート学会大会）論文集：ｐ２０．