Aoki, Y., Nakamura, A., Yokota, T., Saito, T., Okazawa, H., Nagata, T. & Takeda, S. (2010)
In-frame dystrophin following exon 51-skipping improves muscle pathology and function in the exon 52-deficient mdx mouse.
Molecular Therapy 1 November 2010, 18 (11), 1995–2005. doi: 10.1038/mt.2010.186

Konno, M., Hamazaki, T. S., Fukuda, S., Tokuhara, M., Uchiyama, H., Okazawa, H., Okochi, H. & Asashima, M. (2010)
Efficiently differentiating vascular endothelial cells from adipose tissue-derived mesenchymal stem cells in serum-free culture.
Biochemical and Biophysical Research Communications 1 October 2010, 400 (4), 461–465. doi: 10.1016/j.bbrc.2010.08.029

Tamura, T., Horiuchi, D., Chen, Y. C., Sone, M., Miyashita, T., Saitoe, M., Yoshimura, N., Chiang, A. S. & Okazawa, H. (2010)
Drosophila PQBP1 regulates learning acquisition at projection neurons in aversive olfactory conditioning.
Journal of Neuroscience 20 October 2010, 30 (42), 14091–14101. doi: 10.1523/JNEUROSCI.1319-10.2010

Honda, S., Hayashi, S., Imoto, I., Toyama, J., Okazawa, H., Nakagawa, E., Goto, Y. I. & Inazawa, J. (2010)
Copy-number variations on the X chromosome in Japanese patients with mental retardation detected by array-based comparative genomic hybridization analysis.
Journal of Human Genetics 8 September 2010, 55 (9), 590–599. doi: 10.1038/jhg.2010.74

Shiwaku, H., Yoshimura, N., Tamura, T., Sone, M., Ogishima, S., Watase, K., Tagawa, K. & Okazawa, H. (2010)
Suppression of the novel ER protein Maxer by mutant ataxin-1 in Bergman glia contributes to non-cell-autonomous toxicity.
The EMBO Journal 21 July 2010, 29 (14), 2446–2460. doi: 10.1038/emboj.2010.116

Enokido, Y., Tamura, T., Ito, H., Arumughan, A., Komuro, A., Shiwaku, H., Sone, M., Foulle, R., Sawada, H., Ishiguro, H., Ono, T., Murata, M., Kanazawa, I., Tomilin, N., Tagawa, K., Wanker, E. E. & Okazawa, H. (2010)
Mutant huntingtin impairs Ku70-mediated DNA repair.
Journal of Cell Biology 3 May 2010, 189 (3), 425–443. doi: 10.1083/jcb.200905138

Takahashi, M., Mizuguchi, M., Shinoda, H., Aizawa, T., Demura, M., Okazawa, H. & Kawano, K. (2010)
Polyglutamine tract-binding protein-1 binds to U5-15kD via a continuous 23-residue segment of the C-terminal domain.
Biochimica et Biophysica Acta - Proteins and Proteomics 1 July 2010, 1804 (7), 1500–1507. doi: 10.1016/j.bbapap.2010.03.007

Ito, H., Yoshimura, N., Kurosawa, M., Ishii, S., Nukina, N. & Okazawa, H. (2009)
Knock-down of PQBP1 impairs anxiety-related cognition in mouse.
Human Molecular Genetics 6 August 2009, 18 (22), 4239–4254. doi: 10.1093/hmg/ddp378

Chin, J. H., Shiwaku, H., Goda, O., Komuro, A. & Okazawa, H. (2009)
Neural stem cells express Oct-3/4.
Biochemical and Biophysical Research Communications 16 October 2009, 388 (2), 247–251. doi: 10.1016/j.bbrc.2009.07.165

Takahashi, M., Mizuguchi, M., Shinoda, H., Aizawa, T., Demura, M., Okazawa, H. & Kawano, K. (2009)
Polyglutamine tract binding protein-1 is an intrinsically unstructured protein.
Biochimica et Biophysica Acta - Proteins and Proteomics 1 June 2009, 1794 (6), 936–943. doi: 10.1016/j.bbapap.2009.03.001

岡澤均. (2009)
TRIAD―第3の細胞死.
BRAIN and NERVE 1 March 2009, 61 (3), 285–292. doi: 10.11477/mf.1416100446

Morimoto, N., Nagai, M., Miyazaki, K., Kurata, T., Takehisa, Y., Ikeda, Y., Kamiya, T., Okazawa, H. & Abe, K. (2009)
Progressive decrease in the level of YAPdeltaCs, prosurvival isoforms of YAP, in the spinal cord of transgenic mouse carrying a mutant SOD1 gene.
Journal of Neuroscience Research 1 March 2009, 87 (4), 928–936. doi: 10.1002/jnr.21902

Sone, M., Uchida, A., Komatsu, A., Suzuki, E., Ibuki, I., Asada, M., Shiwaku, H., Tamura, T., Hoshino, M., Okazawa, H. & Nabeshima, Y. (2009)
Loss of yata, a Novel Gene Regulating the Subcellular Localization of APPL, Induces Deterioration of Neural Tissues and Lifespan Shortening.
PLoS ONE 11 February 2009, 4 (2), e4466. doi: 10.1371/journal.pone.0004466

Tamura, T., Sone, M., Yamashita, M., Wanker, E. E. & Okazawa, H. (2009)
Glial Cell Lineage Expression of Mutant Ataxin-1 and Huntingtin Induces Developmental and Late-Onset Neuronal Pathologies in Drosophila Models.
PLoS ONE 23 January 2009, 4 (1), e4262. doi: 10.1371/journal.pone.0004262

Takahashi, K., Yoshina, S., Masashi, M., Ito, W., Inoue, T., Shiwaku, H., Arai, H., Mitani, S. & Okazawa, H. (2009)
Nematode Homologue of PQBP1, a Mental Retardation Causative Gene, Is Involved in Lipid Metabolism.
PLoS ONE 1 January 2009, 4 (1), e4104. doi: 10.1371/journal.pone.0004104

Enokido, Y., Yoshitake, A., Ito, H. & Okazawa, H. (2008)
Age-dependent change of HMGB1 and DNA double-strand break accumulation in mouse brain.
Biochemical and Biophysical Research Communications 7 November 2008, 376 (1), 128–133. doi: 10.1016/j.bbrc.2008.08.108

Inagaki, R., Tagawa, K., Qi, M.-L., Enokido, Y., Ito, H., Tamura, T., Shimizu, S., Oyanagi, K., Arai, N., Kanazawa, I., Wanker, E. E. & Okazawa, H. (2008)
Omi / HtrA2 is relevant to the selective vulnerability of striatal neurons in Huntington’s disease.
European Journal of Neuroscience 1 July 2008, 28 (1), 30–40. doi: 10.1111/j.1460-9568.2008.06323.x

Qi, M.-L., Tagawa, K., Enokido, Y., Yoshimura, N., Wada, Y., Watase, K., Ishiura, S., Kanazawa, I., Botas, J., Saitoe, M., Wanker, E. E. & Okazawa, H. (2007)
Proteome analysis of soluble nuclear proteins reveals that HMGB1/2 suppress genotoxic stress in polyglutamine diseases.
Nat. Cell Biol. 1 April 2007, 9 (4), 402–414. doi: 10.1038/ncb1553

Okazawa, H. (2007)
[Is neurodegeneration apoptosis?--Regulation of neuronal death by YAPdeltaC].
Seikagaku February 2007, 79 (2), 157–162.

Tagawa, K., Marubuchi, S., Qi, M.-L., Enokido, Y., Tamura, T., Inagaki, R., Murata, M., Kanazawa, I., Wanker, E. E. & Okazawa, H. (2007)
The Induction Levels of Heat Shock Protein 70 Differentiate the Vulnerabilities to Mutant Huntingtin among Neuronal Subtypes.
J. Neurosci. 24 January 2007, 27 (4), 868. doi: 10.1523/JNEUROSCI.4522-06.2007

Marubuchi, S., Okuda, T., Tagawa, K., Enokido, Y., Horiuchi, D., Shimokawa, R., Tamura, T., Qi, M.-L., Eishi, Y., Watabe, K., Shibata, M., Nakagawa, M. & Okazawa, H. (2006)
Hepatoma-derived growth factor, a new trophic factor for motor neurons, is up-regulated in the spinal cord of PQBP-1 transgenic mice before onset of degeneration.
J. Neurochem. 1 October 2006, 99 (1), 70–83. doi: 10.1111/j.1471-4159.2006.04021.x

Yoshimura, N., Horiuchi, D., Shibata, M., Saitoe, M., Qi, M. ling & Okazawa, H. (2006)
Expression of human PQBP-1 in Drosophila impairs long-term memory and induces abnormal courtship.
FEBS Lett. 17 April 2006, 580 (9), 2335–2340. doi: 10.1016/j.febslet.2006.03.056

Hoshino, M., Qi, M. L., Yoshimura, N., Miyashita, T., Tagawa, K., Wada, Y. I., Enokido, Y., Marubuchi, S., Harjes, P., Arai, N., Oyanagi, K., Blandino, G., Sudol, M., Rich, T., Kanazawa, I., Wanker, E. E., Saitoe, M. & Okazawa, H. (2006)
Transcriptional repression induces a slowly progressive atypical neuronal death associated with changes of YAP isoforms and p73.
J. Cell Biol. 13 February 2006, 172 (4), 589–604. doi: 10.1083/jcb.200509132

Enokido, Y., Suzuki, E., Iwasawa, K., Namekata, K., Okazawa, H. & Kimura, H. (2005)
Cystathionine β‐synthase, a key enzyme for homocysteine metabolism, is preferentially expressed in the radial glia/astrocyte lineage of developing mouse CNS.
FASEB J. 13 November 2005, 19 (13), 1854–1856. doi: 10.1096/fj.05-3724fje

Marubuchi, S., Wada, Y., Okuda, T., Hara, Y., Qi, M., Hoshino, M., Nakagawa, M., Kanazawa, I. & Okazawa, H. (2005)
Polyglutamine tract-binding protein-1 dysfunction induces cell death of neurons through mitochondrial stress.
J. Neurochem. 1 November 2005, 95 (3), 858–870. doi: 10.1111/j.1471-4159.2005.03405.x

Qi, Y., Hoshino, M., Wada, Y., Marubuchi, S., Yoshimura, N., Kanazawa, I., Shinomiya, K. & Okazawa, H. (2005)
PQBP-1 is expressed predominantly in the central nervous system during development.
Eur. J. Neurosci. 27 September 2005, 22 (6), 1277–1286. doi: 10.1111/j.1460-9568.2005.04339.x

Okuda, T., Tagawa, K., Qi, M. L., Hoshio, M., Ueda, H., Kawano, H., Kanazawa, I., Muramatsu, M. & Okazawa, H. (2004)
Oct-3/4 repression accelerates differentiation of neural progenitor cells in vitro and in vivo.
Mol. Brain Res. 6 December 2004, 132 (1), 18–30. doi: 10.1016/j.molbrainres.2004.08.021

Tagawa, K., Hoshino, M., Okuda, T., Ueda, H., Hayashi, H., Engemann, S., Okado, H., Ichikawa, M., Wanker, E. E. & Okazawa, H. (2004)
Distinct aggregation and cell death patterns among different types of primary neurons induced by mutant huntingtin protein.
J. Neurochem. 1 May 2004, 89 (4), 974–987. doi: 10.1111/j.1471-4159.2004.02372.x

Hoshino, M., Tagawa, K., Okuda, T. & Okazawa, H. (2004)
General transcriptional repression by polyglutamine disease proteins is not directly linked to the presence of inclusion bodies.
Biochem. Biophys. Res. Commun. 2 January 2004, 313 (1), 110–116. doi: 10.1016/j.bbrc.2003.11.086

Busch, A., Engemann, S., Lurz, R., Okazawa, H., Lehrach, H. & Wanker, E. E. (2003)
Mutant huntingtin promotes the fibrillogenesis of wild-type huntingtin: A potential mechanism for loss of huntingtin function in Huntington’s disease.
J. Biol. Chem. 17 October 2003, 278 (42), 41452–41461. doi: 10.1074/jbc.M303354200

Hoshino, M., Tagawa, K., Okuda, T., Murata, M., Oyanagi, K., Arai, N., Mizutani, T., Kanazawa, I., Wanker, E. E. & Okazawa, H. (2003)
Histone deacetylase activity is retained in primary neurons expressing mutant huntingtin protein.
J. Neurochem. 5 September 2003, 87 (1), 257–267. doi: 10.1046/j.1471-4159.2003.01991.x

Okuda, T., Hattori, H., Takeuchi, S., Shimizu, J., Ueda, H., Palvimo, J. J., Kanazawa, I., Kawano, H., Nakagawa, M. & Okazawa, H. (2003)
PQBP-1 transgenic mice show a late-onset motor neuron disease-like phenotype.
Hum. Mol. Genet. 1 April 2003, 12 (7), 711–725. doi: 10.1093/hmg/ddg084

Enokido, Y., Maruoka, H., Hatanaka, H., Kanazawa, I. & Okazawa, H. (2002)
PQBP-1 increases vulnerability to low potassium stress and represses transcription in primary cerebellar neurons.
Biochem. Biophys. Res. Commun. 7 June 2002, 294 (2), 268–271. doi: 10.1016/S0006-291X(02)00477-1

Okazawa, H., Rich, T., Chang, A., Lin, X., Waragai, M., Kajikawa, M., Enokido, Y., Komuro, A., Kato, S., Shibata, M., Hatanaka, H., Mouradian, M. M., Sudol, M. & Kanazawa, I. (2002)
Interaction between mutant ataxin-1 and PQBP-1 affects transcription and cell death.
Neuron 30 May 2002, 34 (5), 701–713. doi: 10.1016/S0896-6273(02)00697-9

Ueda, H., Goto, J., Hashida, H., Lin, X., Oyanagi, K., Kawano, H., Zoghbi, H. Y., Kanazawa, I. & Okazawa, H. (2002)
Enhanced SUMOylation in polyglutamine diseases.
Biochem. Biophys. Res. Commun. 26 April 2002, 293 (1), 307–313. doi: 10.1016/S0006-291X(02)00211-5

Shoji, M., Iwakami, N., Takeuchi, S., Waragai, M., Suzuki, M., Kanazawa, I., Lippa, C. F., Ono, S. & Okazawa, H. (2000)
JNK activation is associated with intracellular beta-amyloid accumulation.
Mol. Brain Res. 28 December 2000, 85 (1–2), 221–233. doi: 10.1016/S0169-328X(00)00245-X

Waragai, M., Junn, E., Kajikawa, M., Takeuchi, S., Kanazawa, I., Shibata, M., Mouradian, M. M. & Okazawa, H. (2000)
PQBP-1/Npw38, a nuclear protein binding to the polyglutamine tract, interacts with U5-15kD/dim1p via the carboxyl-terminal domain.
Biochem. Biophys. Res. Commun. 5 July 2000, 273 (2), 592–595. doi: 10.1006/bbrc.2000.2992

Takeuchi, S., Imafuku, I., Waragai, M., Roth, C., Kanazawa, I., Buettner, R., Mouradian, M. M. & Okazawa, H. (1999)
AP-2β represses D(1A) dopamine receptor gene transcription in Neuro2a cells.
Mol. Brain Res. 10 December 1999, 74 (1–2), 208–216. doi: 10.1016/S0169-328X(99)00298-3

Skala, H., Porteu, A., Thomas, M., Szajnert, M. F., Okazawa, H., Kahn, A. & Phan-Dinh-Tuy, F. (1999)
Upstream elements involved in vivo in activation of the brain-specific rat aldolase C gene: Role of binding sites for POU and winged helix proteins.
J. Biol. Chem. 27 November 1999, 273 (48), 31806–31814. doi: 10.1074/jbc.273.48.31806

Imafuku, I., Masaki, T., Waragai, M., Takeuchi, S., Kawabata, M., Hirai, S. I., Ohno, S., Nee, L. E., Lippa, C. F., Kanazawa, I., Imagawa, M. & Okazawa, H. (1999)
Presenilin 1 suppresses the function of c-Jun homodimers via interaction with QM/Jif-1.
J. Cell Biol. 4 October 1999, 147 (1), 121–133. doi: 10.1083/jcb.147.1.121

Waragai, M., Lammers, C. H., Takeuchi, S., Imafuku, I., Udagawa, Y., Kanazawa, I., Kawabata, M., Mouradian, M. M. & Okazawa, H. (1999)
PQBP-1, a novel polyglutamine tract-binding protein, inhibits transcription activation by Brn-2 and affects cell survival.
Hum. Mol. Genet. June 1999, 8 (6), 977–87.

Imafuku, I., Waragai, M., Takeuchi, S., Kanazawa, I., Kawabata, M., Mouradian, M. M. M. & Okazawa, H. (1998)
Polar amino acid-rich sequences bind to polyglutamine tracts.
Biochem. Biophys. Res. Commun. 9 December 1998, 253 (1), 16–20. doi: 10.1006/bbrc.1998.9725

Waragai, M., Imafuku, I., Takeuchi, S., Kanazawa, I., Oyama, F., Udagawa, Y., Kawabata, M. & Okazawa, H. (1997)
Presenilin 1 binds to amyloid precursor protein directly.
Biochem. Biophys. Res. Commun. 20 October 1997, 239 (2), 480–482. doi: 10.1006/bbrc.1997.7488

Okazawa, H., Imafuku, I., Minowa, M. T., Kanazawa, I., Hamada, H. & Mouradian, M. M. (1996)
Regulation of striatal D1A dopamine receptor gene transcription by Brn-4.
Proc. Natl. Acad. Sci. U. S. A. 15 October 1996, 93 (21), 11933–11938. doi: 10.1073/pnas.93.21.11933

Imafuku, I., Kamei, M., Kanazawa, I., Mouradian, M. M. & Okazawa, H. (1996)
POU transcription factors differentially regulate the D(1A) dopamine receptor gene in cultured cells.
Biochem. Biophys. Res. Commun. 24 May 1996, 222 (3), 736–741. doi: 10.1006/bbrc.1996.0813

Okazawa, H., Shimizu, J., Kamei, M., Imafuku, I., Hamada, H. & Kanazawa, I. (1996)
Bcl-2 inhibits retinoic acid-induced apoptosis during the neural differentiation of embryonal stem cells.
J. Cell Biol. 1 March 1996, 132 (5), 955–968. doi: 10.1083/jcb.132.5.955

Okazawa H, Kamei M, Imafuku I, & Kanazawa I. (1994)
Gene regulation of trkB and trkC in the chick retina by light/darkness exposure.
Oncogene 1994, 9 (7), 1813–1818.

Shimazaki, T., Okazawa, H., Fujii, H., Ikeda, M., Tamai, K., McKay, R. D., Muramatsu, M. & Hamada, H. (1993)
Hybrid cell extinction and re-expression of Oct-3 function correlates with differentiation potential.
EMBO J. 1 December 1993, 12 (12), 4489–4498. doi: 10.1002/j.1460-2075.1993.tb06138.x

Okazawa, H., Kamei, M. & Kanazawa, I. (1993)
Molecular cloning and expression of a novel truncated form of chicken trkC.
FEBS Lett. 23 August 1993, 329 (1–2), 171–177. doi: 10.1016/0014-5793(93)80216-H

Okazawa, H., Nishiyama, K., Kamei, M., Washizaki, K., Murayama, S., Kwak, S. & Kanazawa, I. (1993)
TRK immunoreactivity at neuronal dendrite and cell body.
Biochem. Biophys. Res. Commun. 30 July 1993, 194 (2), 683–690. doi: 10.1006/bbrc.1993.1876

Dechant, G., Biffo, S., Okazawa, H., Kolbeck, R., Pottgiesser, J. & Barde, Y. A. (1993)
Expression and binding characteristics of the BDNF receptor chick trkB.
Development 1993, 119 (2),

Okazawa, H., Murata, M., Watanabe, M., Kamei, M. & Kanazawa, I. (1992)
Dopaminergic stimulation up-regulates the in vivo expression of brain-derived neurotrophic factor (BDNF) in the striatum.
FEBS Lett. 23 November 1992, 313 (2), 138–142. doi: 10.1016/0014-5793(92)81430-T

Okazawa, H., Okamoto, K., Ishino, F., Ishino-Kaneko, T., Takeda, S., Toyoda, Y., Muramatsu, M. & Hamada, H. (1991)
The oct3 gene, a gene for an embryonic transcription factor, is controlled by a retinoic acid repressible enhancer.
EMBO J. 1 October 1991, 10 (10), 2997–3005. doi: 10.1002/j.1460-2075.1991.tb07850.x

Okamoto, K., Okazawa, H., Okuda, A., Sakai, M., Muramatsu, M. & Hamada, H. (1990)
A novel octamer binding transcription factor is differentially expressed in mouse embryonic cells.
Cell 9 February 1990, 60 (3), 461–472. doi: 10.1016/0092-8674(90)90597-8