研究業績
2024年
▶︎原著論文
1. Junichiro Wada, Paulina Heponiemi, Kanae Wada, Sufyan Garoushi, Noriyuki Wakabayashi, Tsutomu Iwamoto, Pekka K. Vallittu, Lippo Lassila. Effect of ethylene oxide unit number in bis-EMA on the physical properties of additive-manufactured occlusal splint material. J Prosthodont Res. 2024.01.
2023年
▶︎原著論文
1. Asuna Sugimoto, Kokoro Iwata, Rika Kurogoushi, Manami Tanaka, Yumiko Nakashima, Yoshihito Yamakawa, Atsushi Oishi, Keigo Yoshizaki, Satoshi Fukumoto, Akihito Yamamoto, Naozumi Ishimaru, Tsutomu Iwamoto. C-terminus of PIEZO1 governs Ca2+ influx and intracellular ERK1/2 signaling pathway in mechanotransduction. Biochem Biophys Res Commun. 2023.682 39-45.
2. Junichiro Wada, Kanae Wada, Sadullah Uctasli, Noriyuki Wakabayashi, Tsutomu Iwamoto, Pekka K Vallittu, Lippo Lassila. Effect of splinting material type and location on resistance against deflection force of splinted periodontally compromised teeth with hypermobility. J Mech Behav Biomed Mater. 2023. 142 105873.
3. Yuta Chiba, Keigo Yoshizaki, Hiroshi Sato, Tomoko Ikeuchi, Craig Rhodes, Mitsuki Chiba, Kan Saito, Takashi Nakamura, Tsutomu Iwamoto, Aya Yamada, Yoshihiko Yamada, Satoshi Fukumoto. Deficiency of G protein-coupled receptor Gpr111/Adgrf2 causes enamel hypomineralization in mice by alteration of the expression of kallikrein-related peptidase 4 (Klk4) during pH cycling process. FASEB J. 2023. 37 (4): e22861.
4. Yao Fu, Kanako Miyazaki, Yuta Chiba, Keita Funada, Tomomi Yuta, Tian Tian, Kanji Mizuta, Jumpei Kawahara, Ling Zhang, Daniel Martin, Tsutomu Iwamoto, Ichiro Takahashi, Satoshi Fukumoto, Keigo Yoshizaki. Identification of GPI-anchored protein LYPD1 as an essential factor for odontoblast differentiation in tooth development. J Biol Chem. 2023.299(5):104638.
5. Junichiro Wada, Kanae Wada, Sufyan Garoushi, Akikazu Shinya, Noriyuki Wakabayashi, Tsutomu Iwamoto, Pekka K. Vallittu, Lippo Lassila. Effect of 3D printing system and post-curing atmosphere on micro- and nano-wear of additive-manufactured occlusal splint materials. J Mech Behav Biomed Mater. 2023. 142 105799.
6. Tomomi Yuta, Tian Tian, Yuta Chiba, Kanako Miyazaki, Keita Funada, Kanji Mizuta, Yao Fu, Jumpei Kawahara, Tsutomu Iwamoto, Ichiro Takahashi, Satoshi Fukumoto, Keigo Yoshizaki. Development of a novel ex vivo organ culture system to improve preservation methods of regenerative tissues. Sci Rep. 2023. 13 (1): 3354.
7. Anrizandy Narwidina, Aya Miyazaki, Kokoro Iwata, Rika Kurogoushi, Asuna Sugimoto, Yasusei Kudo, Keita Kawarabayashi, Yoshihito Yamakawa, Yuki Akazawa, Takamasa Kitamura, Hiroshi Nakagawa, Kimiko Yamaguchi-Ueda, Tomokazu Hasegawa, Keigo Yoshizaki, Satoshi Fukumoto, Akihito Yamamoto, Naozumi Ishimaru, Tomonori Iwasaki, Tsutomu Iwamoto. Iroquois homeobox 3 regulates odontoblast proliferation and differentiation mediated by Wnt5a expression. Biochem Biophys Res Commun. 2023. 650 47-54.
8. Yujeong Shin, Kanae Wada, Yumi,Tsuchida Manhal Ijbara, Masaomi Ikeda, Hidekazu Takahashi, Tsutomu Iwamoto. Wear behavior of materials for additive manufacturing after simulated occlusion of deciduous dentition. J Mech Behav Biomed Mater. 2023. 138 105627.
9. Fumiya Kano, Noboru Hashimoto, Yao Liu, Linze Xia, Takaaki Nishihara, Wakana Oki, Keita Kawarabayashi, Noriko Mizusawa, Keiko Aota, Takayoshi Sakai, Masayuki Azuma, Hideharu Hibi, Tomonori Iwasaki, Tsutomu Iwamoto, Nobuyasu Horimai, Akihito Yamamoto. Therapeutic benefits of factors derived from stem cells from human exfoliated deciduous teeth for radiation-induced mouse xerostomia. Sci Rep. 2023. 13 (1): 2706.
10. Zhao Li, Satoko Kakino, Tsutomu Iwamoto. A Characteristic Analysis of the Pulse Transit Time to Dental Pulp: An Attempt at a New Approach to Dental Pulp Diagnoses Based on the Microcirculatory System. J Oral Heal Biosci. 2023. 35 (2): 33-42.
11. Junichiro Wada, Kanae Wada, Mona Gibreel, Noriyuki Wakabayashi, Tsutomu Iwamoto, Pekka K Vallittu, Lippo Lassila. Effect of Surface Polishing on Physical Properties of an Occlusal Splint Material for Additive Manufacturing under Protection Gas Post-Curing Condition. Polymers. 2023.1 (3): 625.
12. Kanae Wada, Manhal Ijbara, Nesreen A Salim, Junichiro Wada, Tsutomu Iwamoto. Three-dimensional microscopic comparison of wear behavior between immature and mature enamel: an in vitro study. BMC Oral Health. 2023. 23 (1): 40.
2022年
▶︎原著論文
1. Aya Yamada, Keigo Yoshizaki, Kan Saito, Masaki Ishikawa, Yuta Chiba, Seira Hoshikawa, Mitsuki Chiba, Ryoko Hino, Yuriko Maruya, Hiroshi Sato, Keiji Masuda, Haruyoshi Yamaza, Takashi Nakamura, Tsutomu Iwamoto, Satoshi Fukumoto. GSK3beta inhibitor-induced dental mesenchymal stem cells regulate ameloblast differentiation. J Oral Biosci. 2022. 64(4):400-409.
2. Junichiro Wada, Kanae Wada, Mona Gibreel, Noriyuki Wakabayashi, Tsutomu Iwamoto, Pekka K. Vallittu, Lippo Lassila. Effect of Nitrogen Gas Post-Curing and Printer Type on the Mechanical Properties of 3D-Printed Hard Occlusal Splint Material. Polymers. 2022.14(19):3971.
3. Junichiro Wada, Kanae Wada, Mona Gibreel, Noriyuki Wakabayashi, Tsutomu Iwamoto, Pekka K. Vallittu, Lippo Lassila. Effect of 3D Printer Type and Use of Protection Gas during Post-Curing on Some Physical Properties of Soft Occlusal Splint Material. Polymers. 2022.14(21): 4618.
4. Tomoko Matsumura, Susumu Hosokawa, Miho Hanaoka, Yushi Abe, Tsutomu Iwamoto, Shigeru Maeda. Transient ventricular bigeminy during emergence from general anesthesia in a pediatric patient with catecholaminergic polymorphic ventricular tachycardia. J Electrocardiol. 2022.73: 38-41.
5. Yao Liu, Fumiya Kano, Noboru Hashimoto, Linze Xia, Qiao Zhou, Xingmei Feng, Hideharu Hibi, Aya Miyazaki, Tsutomu Iwamoto, Yoshizo Matsuka, Zhijun Zhang, Eiji Tanaka, Akihito Yamamoto. Conditioned Medium From the Stem Cells of Human Exfoliated Deciduous Teeth Ameliorates Neuropathic Pain in a Partial Sciatic Nerve Ligation Model. Front Pharmacol. 2022. 13:745020.
6. Tian Tian, Kanako Miyazaki, Yuta Chiba, Keita Funada, Tomomi Yuta, Kanji Mizuta, Yao Fu, Jumpei Kawahara, Xue Han, Yuna Ando, Ami Funada, Aya Yamada, Tsutomu Iwamoto, Seiji Nakamura, Ichiro Takahashi, Satoshi Fukumoto, Keigo Yoshizaki. An ex vivo organ culture screening model revealed that low temperature conditions prevent side effects of anticancer drugs. Sci Rep. 2022. 12(1):3093.
7. Hoshiai Aiko, Kusumoto Yasuka, Hoshiai Taiji, Kimura Naoki, Ito Yukiko, Yoshida Naomi, Shinozuka Osamu, Iwamoto Tsutomu. Factors Influencing Oral Hygiene Management in Patients with Rheumatoid Arthritis 障歯誌. 2022. 43(1):7-16.
8. Nakao Ryoma, Kobayashi Hirotaka, Iwabuchi Yusuke, Kawahara Kazuyoshi, Hirayama Satoru, Ramstedt Madeleine, Sasaki Yuki, Kataoka Michiyo, Akeda Yukihiro, Ohnishi Makoto. A highly immunogenic vaccine platform against encapsulated pathogens using chimeric probiotic Escherichia coli membrane vesicles. NPJ Vaccines. 2022.7(1):153
9. 黒厚子璃佳, 岩田こころ, 中川弘, 長谷川智一, 上田公子, 北村尚正, 赤澤友基, 杉本明日菜, 河原林啓太, 宮嵜 彩, 尼寺理恵, 藤島史帆, 岩崎智憲, 岩本 勉. 当科における 5 年間の障害児 · 有病児の初診時実態 調査．小児歯誌. 2022.02; 60(1); 20-27
▶︎症例報告
1. 金井恵未, 宮新美智世, 上原智己, 和田奏絵, 大石敦之, 長弘茂樹, 柿野聡子, 岩本勉. 歯頸部歯根破折を生じた下顎左側側切歯の 17 年後の経過を評価した 1 例 小児歯誌. 2022.11; 60(3); 141-147
▶︎総説
1. 黒厚子璃佳, 岩田こころ, 岩本 勉. 口腔機能の発達と育成．日本ヘルスケア歯科学会誌. 2022.12; 23(1); 17-23
2. 柿野聡子. 【歯と歯髄領域におけるレーザー · LED 応用の特色ある研究】LED を利用した歯髄血流測定による外傷歯の歯髄診断 日本レーザー医学会誌. 2022.07; 43(2); 91-97
2021年
▶︎原著論文
1. Kokoro Iwata, Keita Kawarabayashi, Keigo Yoshizaki, Tian Tian, Kan Saito, Asuna Sugimoto, Rika Kurogoushi, Aya Yamada, Akihito Yamamoto, Yasuei Kudo, Naozumi Ishimaru, Satoshi Fukumoto, Tsutomu Iwamoto. von Willebrand factor D and EGF domains regulate ameloblast differentiation and enamel formation. J Cell Physiol. 2021.237(3):1964-1979.
2. Yusuke Iwabuchi, Tomoyo Nakamura, Yasuka Kusumoto, Ryoma Nakao, Tsutomu Iwamoto, Osamu Shinozuka, Hidenobu Senpuku. Effects of pH on the Properties of Membrane Vesicles Including Glucosyltransferase in Streptococcus mutans. Microorganisms. 2021.9(11):2308.
3. Taki Sekiya, Kumiko Sugimoto, Ayako Kubota, Natsumi Tsuchihashi, Atsushi Oishi, Naomi Yoshida. Assessment of psychological changes in young children during dental treatment: Analysis of the autonomic nervous activity and electroencephalogram. Int J paediatr dent. 2021.32(3):418-427.
4. Aya Yamada, Keigo Yoshizaki, Masaki Ishikawa, Kan Saito, Yuta Chiba, Emiko Fukumoto, Ryoko Hino, Seria Hoshikawa, Mitsuki Chiba, Takashi Nakamura, Tsutomu Iwamoto, Satoshi Fukumoto. Connexin 43-Mediated Gap Junction Communication Regulates Ameloblast Differentiation via ERK1/2 Phosphorylation. Front Physiol. 2021.12:748574.
5. Rika Kurogoushi, Tomokazu Hasegawa, Yuki Akazawa, Kokoro Iwata, Asuna Sugimoto, Kimiko Yamaguchi-ueda, Aya Miyazaki, Anrizandy Narwidina, Keita Kawarabayashi, Takamasa Kitamura, Hiroshi Nakagawa, Tomonori Iwasaki, Tsutomu Iwamoto. Fibroblast growth factor 2 suppresses the expression of C-C motif chemokine 11 through the c-Jun N-terminal kinase pathway in human dental pulp-derived mesenchymal stem cells. Exp Ther Med. 2021. 22(6):1356.
6. Tamura Yukihiko, Fuangtharnthip Pornpoj, Uehara Tomoki, Iwamoto Tsutomu, Waki Yoshihiro. Metallothionein expression in zinc-treated cartilage precursor ATDC5 cells. Biomed Res Trace Elem. 2021. 32(1); 23-29.
7. Hideo Yonezawa, Mizuho Motegi, Atsushi Oishi,Fuhito Hojo, Seiya Higashi, Eriko Nozaki, Kentaro Oka, Motomichi Takahashi,Takako Osaki, Shigeru Kamiya. Lantibiotics Produced by Oral Inhabitants as a Trigger for Dysbiosis of Human Intestinal Microbiota. Int J Mol Sci. 2021. 22(7):3343.
8. Manami Takenoshita, Masaki Takechi (Co-first), Tri Vu Hoang, Toshiko Furutera, Chisaki Akagawa, Worachat Namangkalakul, Kazushi Aoto, Tsutomu Kume, Miciyo Miyashin, Tsutomu Iwamoto, Sachiko Iseki. Cell lineage- and expression-based inference of the roles of forkhead box transcription factor Foxc2 in craniofacial development. Dev Dyn. 2021.250(8):1125-1139.
▶︎症例報告
1. Yuko Seki, Tomoki Uehara, Miki Uehara, Haruko Fujita, Satoko Kakino, Michiyo Miyashin. Intentional replantation to the endodontic-periodontal disease associated with misplacement of a rubber band-like foreign body: A case report. Ped Dent J. 2021. 32(2):191-196.
2. Atsushi Oishi, Yohei Hama, Emi Kanai, Michiyo Miyashin. Color-changeable chewing gum to motivate chewing training with complete dentures for a male patient with hypohidrotic ectodermal dysplasia and oligodontia. Ped Dent J. 2021. 31(1):123-127.
2020年
▶︎原著論文
1. Shigeki Nagahiro, Tomoki Uehara, Mariko Yamamoto Kawai, Preksa Keo, Toshimi Sato, Hiroki Ochi, Shingo Sato, Shinji Kuroda, Takashi Ono, Michiyo Miyashin, Kazuhiro Aoki. RANKL-binding peptide promotes ectopic bone formation induced by BMP-2 gene transfer in murine gastrocnemius muscle. Dent Oral Maxillofac Res. 2020.6(1):1-6.
2. Komuro Hiroaki, Wint Wit Y., Horiuchi Naohiro, Nozaki Kosuke, Sasano Tetsuo, Miyashin Michiyo, Yamashita Kimihiro, Nagai Akiko. An oriented hydroxyapatite film with arrayed plate-like particles enhance chondrogenic differentiation of ATDC5 cells. J Biomed Mater Res A. 2020.108(3):537-544.
3. Keita Funada, Keigo Yoshizaki, Kanako MIyazaki, Xue Han, Tomomi Yuta, Tian Tian, Kanji Mizuta, Yao Fu, Tsutomu Iwamoto, Aya Yamada, Ichiro Takahashi, Satoshi Fukumoto. microRNA-875-5p plays critical role for mesenchymal condensation in epithelial-mesenchymal interaction during tooth development. Sci Rep. 2020.10(1):4918.
4. Tomoaki Nakamura, Tsutomu Iwamoto, Hannah M Nakamura, Yuki Shindo, Kan Saito, Aya Yamada, Yoshihiko Yamada, Satoshi Fukumoto, Takashi Nakamura. Regulation of miR-1-Mediated Connexin 43 Expression and Cell Proliferation in Dental Epithelial Cells. Front Cell Dev Biol. 2020.8:156.
5. Preksa Keo, Yoshiro Matsumoto, Yasuhiro Shimizu, Shigeki Nagahiro, Masaomi Ikeda, Kazuhiro Aoki, Takashi Ono. A pilot study to investigate the histomorphometric changes of murine maxillary bone around the site of mini-screw insertion in regenerated bone induced by anabolic reagents. Eur J Orthod. 2021.43(1):86-93.
6. N Ogasawara, F Kano, N Hashimoto, H Mori, Y Liu, L Xia, T Sakamaki, H Hibi, T Iwamoto, E Tanaka, A Yamamoto. Factors secreted from dental pulp stem cells show multifaceted benefits for treating experimental temporomandibular joint osteoarthritis. Osteoarthritis Cartilage. 2020. 28(6):831-841.
7. Keita Kawarabayashi, Fumiya Kano, Noboru Hashimoto, Hideharu Hibi, Tsuotmu Iwamoto, Akihihito Yamamoto. Conditioned Media from Human Dental Pulp Stem Cells Prevent Radiation-induced Skin Injury. J Oral Heal Biosci. 2020. 33(1):1-7.
8. Yuta Chiba, Keigo Yoshizaki, Kan Saito, Tomoko Ikeuchi, Tsutomu Iwamoto, Craig Rhodes, Takashi Nakamura, Susana de Vega, Robert J Morell, Erich T Boger, Daniel Martin, Ryoko Hino, Hiroyuki Inuzuka, Christopher K E Bleck, Aya Yamada, Yoshihiko Yamada, Satoshi Fukumoto. G-protein coupled receptor Gpr115 (Adgrf4) is required for enamel mineralization mediated by ameloblasts. J Biol Chem. 2020.295(45):15328-15341.
9. Ijbara Manhal, Wada Kanae, Wada Junichiro, Jayawardena Jayanetti Amiri, Miyashin Michiyo. Replica-based inspection of enamel wear microfeatures. Biomed Mater Eng. 2020.31(5):279-290.
10. Oo Thaw Dar, Satoko Kakino, Masahiko Kusano, Hideharu Ikeda, Michiyo Miyashin, Takashi Okiji. Transmitted-light plethysmography detects changes in human pulpal blood flow elicited by innocuous tooth cooling and foot heating. Arch Oral Biol. 2020.119:104881.
11. Tomoyo Nakamura, Yusuke Iwabuchi, Satoru Hirayama, Naoki Narisawa, Fumio Takenaga, Ryoma Nakao, Hidenobu Senpuku. Roles of membrane vesicles from Streptococcus mutans for the induction of antibodies to glucosyltransferase in mucosal immunity. Microb Pathog. 2020. 149:104260.
12. Ryoko Hino, Aya Yamada, Yuta Chiba, Keigo Yoshizaki, Emiko Fukumoto, Tsutomu Iwamoto, Yuriko Maruya, Keishi Otsu, Hidemistu Harada, Kan Saito, Satoshi Fukumoto. Melnick-Needles syndrome associated molecule, Filamin-A regulates dental epithelial cell migration and root formation. Ped Dent J. 2020.12; 30(3); 208-214.
▶︎症例報告
1. 星合愛子, 吉田直美, 星合泰治, 飯田敏朗, 足達淑子, 隅田由香, 篠塚 修. 歯科衛生過程を用いて問題解決に取り組んだ放射線治療後患者の1症例. 日歯衛誌. 2020.14(2): 93-101.
2. Kusumoto Yasuka, Imai Kohsuke, Ohyama Yoshio, Fukayama Haruhisa, Shinozuka Osamu. Oral management of a patient with down syndrome and agammaglobulinemia: a case report BMC Oral Health. 2020.20(1):71.
3. 黒厚子璃佳, 岩田こころ, 北村尚正, 松立吉弘, 藤田博己, 岩本 勉. 1 歳児の口蓋部に生じたマダニ刺咬症の1例．小児歯誌. 2020.58(3):166-172.
4. 岩田こころ, 黒厚子璃佳, 赤澤友基, 森 浩喜, 岩本 勉. 4歳6ヵ月男児の下顎左側乳犬歯早期脱落歯に対しての1考察. 小児歯誌. 2020. 58(3):204-211.
5. 杉本明日菜, 河原林啓太, 岩本 勉. 口腔機能発達不全を伴う空気嚥下症の児に対し、口腔筋機能療法 (MFT) が有効であった1例. 小児歯誌. 2020.58(3):195-203.
▶︎原著論文
1. Junichiro Wada, Paulina Heponiemi, Kanae Wada, Sufyan Garoushi, Noriyuki Wakabayashi, Tsutomu Iwamoto, Pekka K. Vallittu, Lippo Lassila. Effect of ethylene oxide unit number in bis-EMA on the physical properties of additive-manufactured occlusal splint material. J Prosthodont Res. 2024.01.
2023年
▶︎原著論文
1. Asuna Sugimoto, Kokoro Iwata, Rika Kurogoushi, Manami Tanaka, Yumiko Nakashima, Yoshihito Yamakawa, Atsushi Oishi, Keigo Yoshizaki, Satoshi Fukumoto, Akihito Yamamoto, Naozumi Ishimaru, Tsutomu Iwamoto. C-terminus of PIEZO1 governs Ca2+ influx and intracellular ERK1/2 signaling pathway in mechanotransduction. Biochem Biophys Res Commun. 2023.682 39-45.
2. Junichiro Wada, Kanae Wada, Sadullah Uctasli, Noriyuki Wakabayashi, Tsutomu Iwamoto, Pekka K Vallittu, Lippo Lassila. Effect of splinting material type and location on resistance against deflection force of splinted periodontally compromised teeth with hypermobility. J Mech Behav Biomed Mater. 2023. 142 105873.
3. Yuta Chiba, Keigo Yoshizaki, Hiroshi Sato, Tomoko Ikeuchi, Craig Rhodes, Mitsuki Chiba, Kan Saito, Takashi Nakamura, Tsutomu Iwamoto, Aya Yamada, Yoshihiko Yamada, Satoshi Fukumoto. Deficiency of G protein-coupled receptor Gpr111/Adgrf2 causes enamel hypomineralization in mice by alteration of the expression of kallikrein-related peptidase 4 (Klk4) during pH cycling process. FASEB J. 2023. 37 (4): e22861.
4. Yao Fu, Kanako Miyazaki, Yuta Chiba, Keita Funada, Tomomi Yuta, Tian Tian, Kanji Mizuta, Jumpei Kawahara, Ling Zhang, Daniel Martin, Tsutomu Iwamoto, Ichiro Takahashi, Satoshi Fukumoto, Keigo Yoshizaki. Identification of GPI-anchored protein LYPD1 as an essential factor for odontoblast differentiation in tooth development. J Biol Chem. 2023.299(5):104638.
5. Junichiro Wada, Kanae Wada, Sufyan Garoushi, Akikazu Shinya, Noriyuki Wakabayashi, Tsutomu Iwamoto, Pekka K. Vallittu, Lippo Lassila. Effect of 3D printing system and post-curing atmosphere on micro- and nano-wear of additive-manufactured occlusal splint materials. J Mech Behav Biomed Mater. 2023. 142 105799.
6. Tomomi Yuta, Tian Tian, Yuta Chiba, Kanako Miyazaki, Keita Funada, Kanji Mizuta, Yao Fu, Jumpei Kawahara, Tsutomu Iwamoto, Ichiro Takahashi, Satoshi Fukumoto, Keigo Yoshizaki. Development of a novel ex vivo organ culture system to improve preservation methods of regenerative tissues. Sci Rep. 2023. 13 (1): 3354.
7. Anrizandy Narwidina, Aya Miyazaki, Kokoro Iwata, Rika Kurogoushi, Asuna Sugimoto, Yasusei Kudo, Keita Kawarabayashi, Yoshihito Yamakawa, Yuki Akazawa, Takamasa Kitamura, Hiroshi Nakagawa, Kimiko Yamaguchi-Ueda, Tomokazu Hasegawa, Keigo Yoshizaki, Satoshi Fukumoto, Akihito Yamamoto, Naozumi Ishimaru, Tomonori Iwasaki, Tsutomu Iwamoto. Iroquois homeobox 3 regulates odontoblast proliferation and differentiation mediated by Wnt5a expression. Biochem Biophys Res Commun. 2023. 650 47-54.
8. Yujeong Shin, Kanae Wada, Yumi,Tsuchida Manhal Ijbara, Masaomi Ikeda, Hidekazu Takahashi, Tsutomu Iwamoto. Wear behavior of materials for additive manufacturing after simulated occlusion of deciduous dentition. J Mech Behav Biomed Mater. 2023. 138 105627.
9. Fumiya Kano, Noboru Hashimoto, Yao Liu, Linze Xia, Takaaki Nishihara, Wakana Oki, Keita Kawarabayashi, Noriko Mizusawa, Keiko Aota, Takayoshi Sakai, Masayuki Azuma, Hideharu Hibi, Tomonori Iwasaki, Tsutomu Iwamoto, Nobuyasu Horimai, Akihito Yamamoto. Therapeutic benefits of factors derived from stem cells from human exfoliated deciduous teeth for radiation-induced mouse xerostomia. Sci Rep. 2023. 13 (1): 2706.
10. Zhao Li, Satoko Kakino, Tsutomu Iwamoto. A Characteristic Analysis of the Pulse Transit Time to Dental Pulp: An Attempt at a New Approach to Dental Pulp Diagnoses Based on the Microcirculatory System. J Oral Heal Biosci. 2023. 35 (2): 33-42.
11. Junichiro Wada, Kanae Wada, Mona Gibreel, Noriyuki Wakabayashi, Tsutomu Iwamoto, Pekka K Vallittu, Lippo Lassila. Effect of Surface Polishing on Physical Properties of an Occlusal Splint Material for Additive Manufacturing under Protection Gas Post-Curing Condition. Polymers. 2023.1 (3): 625.
12. Kanae Wada, Manhal Ijbara, Nesreen A Salim, Junichiro Wada, Tsutomu Iwamoto. Three-dimensional microscopic comparison of wear behavior between immature and mature enamel: an in vitro study. BMC Oral Health. 2023. 23 (1): 40.
2022年
▶︎原著論文
1. Aya Yamada, Keigo Yoshizaki, Kan Saito, Masaki Ishikawa, Yuta Chiba, Seira Hoshikawa, Mitsuki Chiba, Ryoko Hino, Yuriko Maruya, Hiroshi Sato, Keiji Masuda, Haruyoshi Yamaza, Takashi Nakamura, Tsutomu Iwamoto, Satoshi Fukumoto. GSK3beta inhibitor-induced dental mesenchymal stem cells regulate ameloblast differentiation. J Oral Biosci. 2022. 64(4):400-409.
2. Junichiro Wada, Kanae Wada, Mona Gibreel, Noriyuki Wakabayashi, Tsutomu Iwamoto, Pekka K. Vallittu, Lippo Lassila. Effect of Nitrogen Gas Post-Curing and Printer Type on the Mechanical Properties of 3D-Printed Hard Occlusal Splint Material. Polymers. 2022.14(19):3971.
3. Junichiro Wada, Kanae Wada, Mona Gibreel, Noriyuki Wakabayashi, Tsutomu Iwamoto, Pekka K. Vallittu, Lippo Lassila. Effect of 3D Printer Type and Use of Protection Gas during Post-Curing on Some Physical Properties of Soft Occlusal Splint Material. Polymers. 2022.14(21): 4618.
4. Tomoko Matsumura, Susumu Hosokawa, Miho Hanaoka, Yushi Abe, Tsutomu Iwamoto, Shigeru Maeda. Transient ventricular bigeminy during emergence from general anesthesia in a pediatric patient with catecholaminergic polymorphic ventricular tachycardia. J Electrocardiol. 2022.73: 38-41.
5. Yao Liu, Fumiya Kano, Noboru Hashimoto, Linze Xia, Qiao Zhou, Xingmei Feng, Hideharu Hibi, Aya Miyazaki, Tsutomu Iwamoto, Yoshizo Matsuka, Zhijun Zhang, Eiji Tanaka, Akihito Yamamoto. Conditioned Medium From the Stem Cells of Human Exfoliated Deciduous Teeth Ameliorates Neuropathic Pain in a Partial Sciatic Nerve Ligation Model. Front Pharmacol. 2022. 13:745020.
6. Tian Tian, Kanako Miyazaki, Yuta Chiba, Keita Funada, Tomomi Yuta, Kanji Mizuta, Yao Fu, Jumpei Kawahara, Xue Han, Yuna Ando, Ami Funada, Aya Yamada, Tsutomu Iwamoto, Seiji Nakamura, Ichiro Takahashi, Satoshi Fukumoto, Keigo Yoshizaki. An ex vivo organ culture screening model revealed that low temperature conditions prevent side effects of anticancer drugs. Sci Rep. 2022. 12(1):3093.
7. Hoshiai Aiko, Kusumoto Yasuka, Hoshiai Taiji, Kimura Naoki, Ito Yukiko, Yoshida Naomi, Shinozuka Osamu, Iwamoto Tsutomu. Factors Influencing Oral Hygiene Management in Patients with Rheumatoid Arthritis 障歯誌. 2022. 43(1):7-16.
8. Nakao Ryoma, Kobayashi Hirotaka, Iwabuchi Yusuke, Kawahara Kazuyoshi, Hirayama Satoru, Ramstedt Madeleine, Sasaki Yuki, Kataoka Michiyo, Akeda Yukihiro, Ohnishi Makoto. A highly immunogenic vaccine platform against encapsulated pathogens using chimeric probiotic Escherichia coli membrane vesicles. NPJ Vaccines. 2022.7(1):153
9. 黒厚子璃佳, 岩田こころ, 中川弘, 長谷川智一, 上田公子, 北村尚正, 赤澤友基, 杉本明日菜, 河原林啓太, 宮嵜 彩, 尼寺理恵, 藤島史帆, 岩崎智憲, 岩本 勉. 当科における 5 年間の障害児 · 有病児の初診時実態 調査．小児歯誌. 2022.02; 60(1); 20-27
▶︎症例報告
1. 金井恵未, 宮新美智世, 上原智己, 和田奏絵, 大石敦之, 長弘茂樹, 柿野聡子, 岩本勉. 歯頸部歯根破折を生じた下顎左側側切歯の 17 年後の経過を評価した 1 例 小児歯誌. 2022.11; 60(3); 141-147
▶︎総説
1. 黒厚子璃佳, 岩田こころ, 岩本 勉. 口腔機能の発達と育成．日本ヘルスケア歯科学会誌. 2022.12; 23(1); 17-23
2. 柿野聡子. 【歯と歯髄領域におけるレーザー · LED 応用の特色ある研究】LED を利用した歯髄血流測定による外傷歯の歯髄診断 日本レーザー医学会誌. 2022.07; 43(2); 91-97
2021年
▶︎原著論文
1. Kokoro Iwata, Keita Kawarabayashi, Keigo Yoshizaki, Tian Tian, Kan Saito, Asuna Sugimoto, Rika Kurogoushi, Aya Yamada, Akihito Yamamoto, Yasuei Kudo, Naozumi Ishimaru, Satoshi Fukumoto, Tsutomu Iwamoto. von Willebrand factor D and EGF domains regulate ameloblast differentiation and enamel formation. J Cell Physiol. 2021.237(3):1964-1979.
2. Yusuke Iwabuchi, Tomoyo Nakamura, Yasuka Kusumoto, Ryoma Nakao, Tsutomu Iwamoto, Osamu Shinozuka, Hidenobu Senpuku. Effects of pH on the Properties of Membrane Vesicles Including Glucosyltransferase in Streptococcus mutans. Microorganisms. 2021.9(11):2308.
3. Taki Sekiya, Kumiko Sugimoto, Ayako Kubota, Natsumi Tsuchihashi, Atsushi Oishi, Naomi Yoshida. Assessment of psychological changes in young children during dental treatment: Analysis of the autonomic nervous activity and electroencephalogram. Int J paediatr dent. 2021.32(3):418-427.
4. Aya Yamada, Keigo Yoshizaki, Masaki Ishikawa, Kan Saito, Yuta Chiba, Emiko Fukumoto, Ryoko Hino, Seria Hoshikawa, Mitsuki Chiba, Takashi Nakamura, Tsutomu Iwamoto, Satoshi Fukumoto. Connexin 43-Mediated Gap Junction Communication Regulates Ameloblast Differentiation via ERK1/2 Phosphorylation. Front Physiol. 2021.12:748574.
5. Rika Kurogoushi, Tomokazu Hasegawa, Yuki Akazawa, Kokoro Iwata, Asuna Sugimoto, Kimiko Yamaguchi-ueda, Aya Miyazaki, Anrizandy Narwidina, Keita Kawarabayashi, Takamasa Kitamura, Hiroshi Nakagawa, Tomonori Iwasaki, Tsutomu Iwamoto. Fibroblast growth factor 2 suppresses the expression of C-C motif chemokine 11 through the c-Jun N-terminal kinase pathway in human dental pulp-derived mesenchymal stem cells. Exp Ther Med. 2021. 22(6):1356.
6. Tamura Yukihiko, Fuangtharnthip Pornpoj, Uehara Tomoki, Iwamoto Tsutomu, Waki Yoshihiro. Metallothionein expression in zinc-treated cartilage precursor ATDC5 cells. Biomed Res Trace Elem. 2021. 32(1); 23-29.
7. Hideo Yonezawa, Mizuho Motegi, Atsushi Oishi,Fuhito Hojo, Seiya Higashi, Eriko Nozaki, Kentaro Oka, Motomichi Takahashi,Takako Osaki, Shigeru Kamiya. Lantibiotics Produced by Oral Inhabitants as a Trigger for Dysbiosis of Human Intestinal Microbiota. Int J Mol Sci. 2021. 22(7):3343.
8. Manami Takenoshita, Masaki Takechi (Co-first), Tri Vu Hoang, Toshiko Furutera, Chisaki Akagawa, Worachat Namangkalakul, Kazushi Aoto, Tsutomu Kume, Miciyo Miyashin, Tsutomu Iwamoto, Sachiko Iseki. Cell lineage- and expression-based inference of the roles of forkhead box transcription factor Foxc2 in craniofacial development. Dev Dyn. 2021.250(8):1125-1139.
▶︎症例報告
1. Yuko Seki, Tomoki Uehara, Miki Uehara, Haruko Fujita, Satoko Kakino, Michiyo Miyashin. Intentional replantation to the endodontic-periodontal disease associated with misplacement of a rubber band-like foreign body: A case report. Ped Dent J. 2021. 32(2):191-196.
2. Atsushi Oishi, Yohei Hama, Emi Kanai, Michiyo Miyashin. Color-changeable chewing gum to motivate chewing training with complete dentures for a male patient with hypohidrotic ectodermal dysplasia and oligodontia. Ped Dent J. 2021. 31(1):123-127.
2020年
▶︎原著論文
1. Shigeki Nagahiro, Tomoki Uehara, Mariko Yamamoto Kawai, Preksa Keo, Toshimi Sato, Hiroki Ochi, Shingo Sato, Shinji Kuroda, Takashi Ono, Michiyo Miyashin, Kazuhiro Aoki. RANKL-binding peptide promotes ectopic bone formation induced by BMP-2 gene transfer in murine gastrocnemius muscle. Dent Oral Maxillofac Res. 2020.6(1):1-6.
2. Komuro Hiroaki, Wint Wit Y., Horiuchi Naohiro, Nozaki Kosuke, Sasano Tetsuo, Miyashin Michiyo, Yamashita Kimihiro, Nagai Akiko. An oriented hydroxyapatite film with arrayed plate-like particles enhance chondrogenic differentiation of ATDC5 cells. J Biomed Mater Res A. 2020.108(3):537-544.
3. Keita Funada, Keigo Yoshizaki, Kanako MIyazaki, Xue Han, Tomomi Yuta, Tian Tian, Kanji Mizuta, Yao Fu, Tsutomu Iwamoto, Aya Yamada, Ichiro Takahashi, Satoshi Fukumoto. microRNA-875-5p plays critical role for mesenchymal condensation in epithelial-mesenchymal interaction during tooth development. Sci Rep. 2020.10(1):4918.
4. Tomoaki Nakamura, Tsutomu Iwamoto, Hannah M Nakamura, Yuki Shindo, Kan Saito, Aya Yamada, Yoshihiko Yamada, Satoshi Fukumoto, Takashi Nakamura. Regulation of miR-1-Mediated Connexin 43 Expression and Cell Proliferation in Dental Epithelial Cells. Front Cell Dev Biol. 2020.8:156.
5. Preksa Keo, Yoshiro Matsumoto, Yasuhiro Shimizu, Shigeki Nagahiro, Masaomi Ikeda, Kazuhiro Aoki, Takashi Ono. A pilot study to investigate the histomorphometric changes of murine maxillary bone around the site of mini-screw insertion in regenerated bone induced by anabolic reagents. Eur J Orthod. 2021.43(1):86-93.
6. N Ogasawara, F Kano, N Hashimoto, H Mori, Y Liu, L Xia, T Sakamaki, H Hibi, T Iwamoto, E Tanaka, A Yamamoto. Factors secreted from dental pulp stem cells show multifaceted benefits for treating experimental temporomandibular joint osteoarthritis. Osteoarthritis Cartilage. 2020. 28(6):831-841.
7. Keita Kawarabayashi, Fumiya Kano, Noboru Hashimoto, Hideharu Hibi, Tsuotmu Iwamoto, Akihihito Yamamoto. Conditioned Media from Human Dental Pulp Stem Cells Prevent Radiation-induced Skin Injury. J Oral Heal Biosci. 2020. 33(1):1-7.
8. Yuta Chiba, Keigo Yoshizaki, Kan Saito, Tomoko Ikeuchi, Tsutomu Iwamoto, Craig Rhodes, Takashi Nakamura, Susana de Vega, Robert J Morell, Erich T Boger, Daniel Martin, Ryoko Hino, Hiroyuki Inuzuka, Christopher K E Bleck, Aya Yamada, Yoshihiko Yamada, Satoshi Fukumoto. G-protein coupled receptor Gpr115 (Adgrf4) is required for enamel mineralization mediated by ameloblasts. J Biol Chem. 2020.295(45):15328-15341.
9. Ijbara Manhal, Wada Kanae, Wada Junichiro, Jayawardena Jayanetti Amiri, Miyashin Michiyo. Replica-based inspection of enamel wear microfeatures. Biomed Mater Eng. 2020.31(5):279-290.
10. Oo Thaw Dar, Satoko Kakino, Masahiko Kusano, Hideharu Ikeda, Michiyo Miyashin, Takashi Okiji. Transmitted-light plethysmography detects changes in human pulpal blood flow elicited by innocuous tooth cooling and foot heating. Arch Oral Biol. 2020.119:104881.
11. Tomoyo Nakamura, Yusuke Iwabuchi, Satoru Hirayama, Naoki Narisawa, Fumio Takenaga, Ryoma Nakao, Hidenobu Senpuku. Roles of membrane vesicles from Streptococcus mutans for the induction of antibodies to glucosyltransferase in mucosal immunity. Microb Pathog. 2020. 149:104260.
12. Ryoko Hino, Aya Yamada, Yuta Chiba, Keigo Yoshizaki, Emiko Fukumoto, Tsutomu Iwamoto, Yuriko Maruya, Keishi Otsu, Hidemistu Harada, Kan Saito, Satoshi Fukumoto. Melnick-Needles syndrome associated molecule, Filamin-A regulates dental epithelial cell migration and root formation. Ped Dent J. 2020.12; 30(3); 208-214.
▶︎症例報告
1. 星合愛子, 吉田直美, 星合泰治, 飯田敏朗, 足達淑子, 隅田由香, 篠塚 修. 歯科衛生過程を用いて問題解決に取り組んだ放射線治療後患者の1症例. 日歯衛誌. 2020.14(2): 93-101.
2. Kusumoto Yasuka, Imai Kohsuke, Ohyama Yoshio, Fukayama Haruhisa, Shinozuka Osamu. Oral management of a patient with down syndrome and agammaglobulinemia: a case report BMC Oral Health. 2020.20(1):71.
3. 黒厚子璃佳, 岩田こころ, 北村尚正, 松立吉弘, 藤田博己, 岩本 勉. 1 歳児の口蓋部に生じたマダニ刺咬症の1例．小児歯誌. 2020.58(3):166-172.
4. 岩田こころ, 黒厚子璃佳, 赤澤友基, 森 浩喜, 岩本 勉. 4歳6ヵ月男児の下顎左側乳犬歯早期脱落歯に対しての1考察. 小児歯誌. 2020. 58(3):204-211.
5. 杉本明日菜, 河原林啓太, 岩本 勉. 口腔機能発達不全を伴う空気嚥下症の児に対し、口腔筋機能療法 (MFT) が有効であった1例. 小児歯誌. 2020.58(3):195-203.