研究業績
2025年
▶︎原著論文
1. Yuika Yamanaka, Kanae Wada, Shinya Oishi, Daiki Kondo, Yujeong Shin, Kaori Kohi, Misaki Hamashima,Asuna Sugimoto, Atsushi Oishi, Wataru Komada, Tsutomu Iwamoto. Effect of crown-core material combinations on cervical surface strain and of crown type on antagonist enamel wear in a simulated deciduous tooth model Dental Materials. 2025.10; 42(2); 219-226
2. Asuna Sugimoto, Kokoro Iwata, Rika Kurogoushi, Tsutomu Iwamoto. Successful correction of tooth eruption disturbance caused by mandibular enostosis using a pinhole perforation technique Pediatric Dental Journal. 2025.12; 35(3); 100365
3. Yumiko Nakashima, Kokoro Iwata, Asuna Sugimoto, Manami Tanaka, Muhammad Dhiaulfikri Nauval Hadiana, Nodoka Ato, Atsushi Oishi, Kanae Wada, Yuta Chiba, Triana Marchelina, Aya Yamada, Satoshi Fukumoto, Akihito Yamamoto, Tsutomu Iwamoto. Identification of a desmocollin 3-β-catenin complex modulated by Vwde-calpain signaling in ameloblast differentiation. Biochemical and Biophysical Research Communications. 2025.11; 792; 153000
4. Satoko Kakino, Hiroaki Ohki, Kaori Kohi, Yuko Matsumura, Tsutomu Iwamoto. Diagnostic accuracy of Transmitted-light plethysmography for the assessment of pulpal circulation in traumatized young permanent incisors Scientific Reports. 2025.11; 15; 42579
5. Triana Marchelina, Yuta Chiba, Shinji Otake, Li Wanshu, Hiroshi Sato, Yumiko Nakashima, Asuna Sugimoto, Tsutomu Iwamoto, Aya Yamada, Kan Saito, Satoshi Fukumoto. Expression patterns of desmosome family members during tooth development and the role of Desmocollin-3 in cytodifferentiation of stratum intermedium. Arch Oral Biol. 2025.09; 180; 106404
6. Kusumoto Yasuka, Iwabuchi Yusuke, Shindo Yuki, Sugimoto Asuna, Soma Chihiro, Watanabe Mayuko, Aida Takae, Iwamoto Tsutomu. Lower Lip Cellulitis Secondary to Apical Periodontitis in a Patient with Cerebral Palsy Associated with Intellectual Disability Journal of Oral Health and Biosciences. 2025.09; 38(1); 13-17
7. Kaori Kohi, Yumi Tsuchida, Kanae Wada, Yumiko Nakashima, Tsutomu Iwamoto, Hidekazu Takahashi. Machining accuracy of pediatric partial dentures using computer-aided design-computer aided manufacturing (CAD-CAM) system Journal of Clinical Pediatric Dentistry. 2025.06; 50(1); 103-113
8. Iwabuchi Y, Yoshida H, Kamei S, Uematsu T, Saito M, Senpuku H. Formation of Mono-Organismal and Mixed Staphylococcus aureus and Streptococcus mutans Biofilms in the Presence of NaCl. Microorganisms. 2025.05; 13(5);
9. Hiroaki Ohki, Satoko Kakino, Tsutomu Iwamoto. Evaluation of tooth-specific optical properties for the development of a non-invasive pulp diagnostic system using Transmitted-light plethysmography: An in vitro study. Archives of Oral Biology. 2025.04; Apr:172;
10. Kanae Wada, Sufyan Garoushi, Junichiro Wada, Tsutomu Iwamoto, Pekka K. Vallittu, Lippo Lassila. Mechanical and Structural Characterization of CAD-CAM Materials and Enamel of Deciduous and Permanent Teeth Dental Materials Journal. 2025.02; 44(2); 146-156
▶書籍等出版物
1. 和田 奏絵, 岩本 勉, 北村 和夫 他. 続・日常臨床のレベルアップ＆ヒント67選. デンタルダイヤモンド, 2025.04
▶総説
1. 杉本 明日菜. ピエゾ１機械受容チャネル（PIEZO1）による骨髄由来間葉系幹細胞における硬組織形成能の検討小児歯科学雑誌. 2025.02; 63(1); 1-4
▶講演・口頭発表等
1. Satoko Kakino, Yuko Matsumura, Taki Sekiya, Tsutomu Iwamoto. A case of intentional replantation of a young permanent incisor with pulp infection due to abnormal crown morphology and dental trauma.. The 11th Conference of Asian International Association of Dental Traumatology 2025.03.29 Held in journal
2. Satoko Kakino. Supporting Children with Cancer: Oral Care and Management of Oral Mucositis in a Hospital Setting.. International online conference on Children with Special health care needs. 2025.03.28
Online conference
3. Junichiro Wada, Kanae Wada, Pekka K. Vallittu, Lippo Lassila. Bacteria adhesion to additive-manufactured occlusal splint. 5th TCBC Midwinter Meeting 2025.02.12 Turku, Finland
1. 柿野 聡子. 歯· 口のけがとその対応—応急処置と経過観察の実際—. 町田市学校保健会小中合同養護部会 2025 年度歯科保健研修会2025.12.22 東京都町田市
2. 真藤 裕基, 中村 はな,中井 淳一,若森 実,中村 卓史. 唾液腺発生において神経制御下で機能する組織構築機構の解明. 第4回日本唾液ケア科学会学術集会2025.11.23
3. 柿野 聡子. 原発性免疫不全症候群の歯科的支援ー歯科治療と口腔粘膜炎のケアー. 2025年第1回医療講演会2025.11.16 東京
4. 内海 希、千葉 真子、脇田 亮、岩渕 佑介、真藤 祐基、楠本 康香、前田 茂. 知的能力障害を伴う病的肥満患者に対する全身麻酔下歯科治療の一例. 第42回日本障害者歯科学会2025.11.02大阪
5. 真藤 裕基, 相馬 千紘, 渡辺 真柚子, 岩淵 佑介, 大木 栞,楠本 康香,伊藤 孝哉,吉野 綾,石川 健太郎,前田 茂, 岩本 勉. ブラキシズムによる著しい咬合性外傷を認めたRett症候群の1症例. 第42回日本障害者歯科学会総会および学術大会2025.11.02
6. 柿野聡子, 田中眞実, 松村木綿子, 岩本 勉. 多発性歯内歯を認めた頭蓋外胚葉異形成症（Sensenbrenner症候群）に対し歯科的対応を行った1例. 第42回日本障害者歯科学会総会·学術大会2025.11.02大阪
7. 山内 英史,岩淵 佑介,鈴木 朋,内田 博之,北村 新,初野 有人,戸坂 清二,原田 達也,丸山 清孝,白井 弘三,新井 曄子, 時田 英紀,松本 勝洋,脇田 亮,篠塚 修. Rubinstein-Taybi症候群患者における長期口腔管理の1例. 第42回公益社団法人日本障害者歯科学会総会および学術大会2025.11.02 大阪
8. 相馬千紘,楠本 康香,岩淵 佑介,渡辺 真柚子,真藤 裕基,杉本 明日菜,平和田 智佳,岩本 勉. Fontan術後遠隔期の歯科治療の1例. 第42回日本障害者歯科学会総会および学術大会2025.11.02
9. 渡辺 真柚子,岩淵 佑介,星合 泰治,杉本 明日菜,真藤 裕基,平和田 智佳,楠本 康香,相田 貴絵,鈴木 朋,渡邊 麻里子,星合 愛子,相馬 千紘,岩本 勉. Fontan手術後遠隔期患者の歯科治療経験. 第42回日本障害者歯科学会総会および学術大会2025.11.02
10. 田中 眞実. 歯の発生メカニズムの解明および応用モデルの構築、日本障害者歯科学会. 2025.11.01 大阪
11. 新田 瑠璃子，柿野 聡子，歸山 えりか，松村 木綿子，岩本 勉. 舌下免疫療法中に浮腫性歯肉腫脹を認めた1例. 2025.10.05 東京
12. 浜島 美咲, 和田 奏絵, 小樋 香織, 山中 柚衣香,岩本 勉. デジタル口腔内スキャナーを活用した視覚的指導による口腔内情報の共有と支援アプローチ. 小児歯科学会第40回関東地方会大会·総会2025.10.05船堀
13. 中島 結美子, 岩田 こころ,杉本 明日菜,岩本 勉. 歯の発生過程におけるDesomocollin3の発現. 小児歯科学会第40 回関東地方会大会·総会2025.10.05 船堀
14. 中島 結美子,黒厚子 璃佳,岩田 こころ,杉本 明日菜,岩本 勉. 食生活調査票の記載から齲蝕重症度が評価できる.第72回日本小児保健協会学術集会2025.06.28 金沢
15. 武永 嶺, 柿野 聡子,松村 木綿子,平和田 智佳,岩本 勉. 脱落乳歯の再植部より歯冠の形態異常を伴う後継永久歯の早期萠出がみられた1例. 2025.05.30 新潟
16. 椿 礼子,大石 敦之,北市 裕大,岩淵 佑介,山中 柚衣香,杉本 明日菜,和田 奏絵,荒川 真一,岩本 勉. 新規根管洗浄液の探索における効果的な感染根管モデルの作製. 第63回日本小児歯科学会大会2025.05.29
17. 大石 敦之,北市 裕大,椿 礼子,岩淵 佑介,山中 柚衣香,杉本 明日菜,和田 奏絵,荒川 真一,岩本 勉. 高純度次亜塩素酸水の感染根管モデルを用いた抗菌·洗浄効果の検証. 第63回日本小児歯科学会大会2025.05.29新潟県新潟市
18. 加藤 音々、大石 敦之、杉本 明日菜、岩田 こころ、黒厚子 璃佳、内藤 悠、岩本 勉. 医科歯科連携の発展における医科棟手術室·病棟への可搬歯科ユニット実装過程. 第63回日本小児歯科学会大会2025.05.29新潟県新潟市
19. 内藤 悠, 松村 木綿子,和田 奏絵,岩本 勉. 第一大臼歯の遠心移動により,自然放出を認めた埋伏第二乳臼歯の１例. 第63回日本小児歯科学会大会2025.05.29 新潟県新潟市
20. 山中 柚衣香，和田 奏絵，Yujeong Shin，小樋 香織，浜島 美咲，杉本 明日菜，大石 敦之，岩本 勉. コア材料およびクラウン材料が乳臼歯歯頸部のひずみに及ぼす影響. 第63回日本小児歯科学会2025.05.29新潟県，新潟市
21. 大石 敦之. 小児患者における口腔外傷の初期対応. 日本外傷歯学会第15回 東日本地方会総会·学術大会教育講演 2025.05.25 埼玉県さいたま市
22. 関矢 多希、小樋 香織、柿野 聡子. 小児歯科専門医院における口腔外傷の実態調査. 第15回日本外傷歯学会東日本地方会学術大会2025.05.25 埼玉
23. 柿野 聡子. 子どもの口とケガ ～知っておきたい基本と応急処置～.. 東京都多摩立川保健所令和7年度保育園幼稚園歯科保健担当者研修会2025.05.23
24. 中島 結美子，黒厚子 璃佳，杉本 明日菜，岩田 こころ，岩本 勉. 平日·休日の起床および就寝時間のずれが齲蝕重症度と相関する. 第11回日本小児診療多職種研究会2025.03.08 広島
25. 真藤 裕基, 中村 卓史,楠本 康香,岩本 勉. 発生期唾液腺における副交感神経による筋上皮細胞の分化誘導機構の解明. 口腔病学会雑誌2025.03.01
▶受賞
1. Best presentation award (Division Excellence Awards-Pediatric Dentistry Division)：柿野 聡子, アジア外傷歯学会, 2025年03月
2. 大石 敦之：第63回日本小児歯科学会大会SHOFUAWARD（材料部門：高純度次亜塩素酸水の感染根管モデルを用いた抗菌·洗浄効果の検証）,日本小児歯科学会,2025年05月
3. 田中 眞実：第63回日本小児歯科学会大会：デンツプライシロナ賞,2025年05月
4. 中島 結美子：第72回日本小児保健協会学術集会 若手奨励賞,2025年06月
5. 日本障害者歯科学会 若手学術奨励賞：田中 眞実,2025年11月
6. 優秀論文賞：真藤 裕基,日本唾液ケア科学会,2025年11月
7. 日本障害者歯科学会若手学術奨励賞：岩淵 佑介,公益社団法人日本障害者歯科学会,2025年11月
2024年
▶︎原著論文
1. Junichiro Wada, Paulina Heponiemi, Kanae Wada, Sufyan Garoushi, Noriyuki Wakabayashi, Tsutomu Iwamoto, Pekka K. Vallittu, Lippo Lassila. Effect of ethylene oxide unit number in bis-EMA on the physical properties of additive-manufactured occlusal splint material. J Prosthodont Res. 2024.01.
2. Manami Tanaka, Asuna Sugimoto, Kokoro Iwata, Yumiko Nakashima, Muhammad Dhiaulfikri Nauval
Hadiana, Yusuke Iwabuchi, Kanae Wada, Atsushi Oishi, Tsutomu Iwamoto. Prrx2, the paired-related
homeobox transcription factor, functions as a potential regulator of pannexin 3 expression in odontoblast
differentiation. J Oral Biosci. 2024.12; 100601
3. Wada K, Wada J, Uctasli MB, Uctasli S, Yavuz Y, Iwamoto T, Vallittu PK, Garoushi S, Lassila L. Impact
of restorative material on fracture behaviors of class II restoration in endodontically treated deciduous
molars. Dental materials journal. 2024.08;
4. Wakita R, Kusumoto Y, Shinozuka O, Tokyo Metropolitan Hachinan Dental Association, Fukayama H,
Maeda S. Dental findings and intravenous sedation in a patient with Potocki-Lupski syndrome: A case
report. Special care in dentistry : official publication of the American Association of Hospital Dentists, the
Academy of Dentistry for the Handicapped, and the American Society for Geriatric Dentistry. 2024.05;
5. Lippo Lassila, Mine B. Uctasli, Kanae Wada, Pekka K. Vallittu, and Sufyan Garoushi. Effect of different
beverages and polishing techniques on colour stability of CAD/CAM composite restorative materials.
Biomaterial Investigations in Dentistry. 2024.04; 11; 34-41
▶︎症例報告
1. 高石和美、杉本明日菜、北村尚正、前尾 慶、藤原茂樹、西川美佳、藤田創詩、岩本 勉、川人 伸次. 先天性 QT 延長症候群3型患者に対し歯科治療時の全身管理を行った1例 2024.10; 45(3); 165-171
2. 柿野 聡子. 【外傷歯のアプローチ】初診時の診断と対応、予後の観察について 小児歯科臨床. 2024.06; 29(6);6-15
3. 倉重 圭史, 土岐 志麻, 鈴木 広幸, 田中 克明, 村井 雄司, 石通 宏行, 柿野 聡子, 桑原 康生, 近藤 有紀, 榊原 さや夏, 佐野 正之, 鈴木 淳司, 中村 由紀, 星川 聖良, 蓑輪 映里佳, 湯浅 健司, 苅部 洋行, 早崎 治明, 朝田 芳信,齊藤 正人. 口腔機能発達不全症の管理指導におけるオンライン診療に対する評価 小児歯科学雑誌. 2024.06; 62(2); 44-52
▶︎原著論文
1. Asuna Sugimoto, Kokoro Iwata, Rika Kurogoushi, Manami Tanaka, Yumiko Nakashima, Yoshihito Yamakawa, Atsushi Oishi, Keigo Yoshizaki, Satoshi Fukumoto, Akihito Yamamoto, Naozumi Ishimaru, Tsutomu Iwamoto. C-terminus of PIEZO1 governs Ca2+ influx and intracellular ERK1/2 signaling pathway in mechanotransduction. Biochem Biophys Res Commun. 2023.682 39-45.
2. Junichiro Wada, Kanae Wada, Sadullah Uctasli, Noriyuki Wakabayashi, Tsutomu Iwamoto, Pekka K Vallittu, Lippo Lassila. Effect of splinting material type and location on resistance against deflection force of splinted periodontally compromised teeth with hypermobility. J Mech Behav Biomed Mater. 2023. 142 105873.
3. Yuta Chiba, Keigo Yoshizaki, Hiroshi Sato, Tomoko Ikeuchi, Craig Rhodes, Mitsuki Chiba, Kan Saito, Takashi Nakamura, Tsutomu Iwamoto, Aya Yamada, Yoshihiko Yamada, Satoshi Fukumoto. Deficiency of G protein-coupled receptor Gpr111/Adgrf2 causes enamel hypomineralization in mice by alteration of the expression of kallikrein-related peptidase 4 (Klk4) during pH cycling process. FASEB J. 2023. 37 (4): e22861.
4. Yao Fu, Kanako Miyazaki, Yuta Chiba, Keita Funada, Tomomi Yuta, Tian Tian, Kanji Mizuta, Jumpei Kawahara, Ling Zhang, Daniel Martin, Tsutomu Iwamoto, Ichiro Takahashi, Satoshi Fukumoto, Keigo Yoshizaki. Identification of GPI-anchored protein LYPD1 as an essential factor for odontoblast differentiation in tooth development. J Biol Chem. 2023.299(5):104638.
5. Junichiro Wada, Kanae Wada, Sufyan Garoushi, Akikazu Shinya, Noriyuki Wakabayashi, Tsutomu Iwamoto, Pekka K. Vallittu, Lippo Lassila. Effect of 3D printing system and post-curing atmosphere on micro- and nano-wear of additive-manufactured occlusal splint materials. J Mech Behav Biomed Mater. 2023. 142 105799.
6. Tomomi Yuta, Tian Tian, Yuta Chiba, Kanako Miyazaki, Keita Funada, Kanji Mizuta, Yao Fu, Jumpei Kawahara, Tsutomu Iwamoto, Ichiro Takahashi, Satoshi Fukumoto, Keigo Yoshizaki. Development of a novel ex vivo organ culture system to improve preservation methods of regenerative tissues. Sci Rep. 2023. 13 (1): 3354.
7. Anrizandy Narwidina, Aya Miyazaki, Kokoro Iwata, Rika Kurogoushi, Asuna Sugimoto, Yasusei Kudo, Keita Kawarabayashi, Yoshihito Yamakawa, Yuki Akazawa, Takamasa Kitamura, Hiroshi Nakagawa, Kimiko Yamaguchi-Ueda, Tomokazu Hasegawa, Keigo Yoshizaki, Satoshi Fukumoto, Akihito Yamamoto, Naozumi Ishimaru, Tomonori Iwasaki, Tsutomu Iwamoto. Iroquois homeobox 3 regulates odontoblast proliferation and differentiation mediated by Wnt5a expression. Biochem Biophys Res Commun. 2023. 650 47-54.
8. Yujeong Shin, Kanae Wada, Yumi,Tsuchida Manhal Ijbara, Masaomi Ikeda, Hidekazu Takahashi, Tsutomu Iwamoto. Wear behavior of materials for additive manufacturing after simulated occlusion of deciduous dentition. J Mech Behav Biomed Mater. 2023. 138 105627.
9. Fumiya Kano, Noboru Hashimoto, Yao Liu, Linze Xia, Takaaki Nishihara, Wakana Oki, Keita Kawarabayashi, Noriko Mizusawa, Keiko Aota, Takayoshi Sakai, Masayuki Azuma, Hideharu Hibi, Tomonori Iwasaki, Tsutomu Iwamoto, Nobuyasu Horimai, Akihito Yamamoto. Therapeutic benefits of factors derived from stem cells from human exfoliated deciduous teeth for radiation-induced mouse xerostomia. Sci Rep. 2023. 13 (1): 2706.
10. Zhao Li, Satoko Kakino, Tsutomu Iwamoto. A Characteristic Analysis of the Pulse Transit Time to Dental Pulp: An Attempt at a New Approach to Dental Pulp Diagnoses Based on the Microcirculatory System. J Oral Heal Biosci. 2023. 35 (2): 33-42.
11. Junichiro Wada, Kanae Wada, Mona Gibreel, Noriyuki Wakabayashi, Tsutomu Iwamoto, Pekka K Vallittu, Lippo Lassila. Effect of Surface Polishing on Physical Properties of an Occlusal Splint Material for Additive Manufacturing under Protection Gas Post-Curing Condition. Polymers. 2023.1 (3): 625.
12. Kanae Wada, Manhal Ijbara, Nesreen A Salim, Junichiro Wada, Tsutomu Iwamoto. Three-dimensional microscopic comparison of wear behavior between immature and mature enamel: an in vitro study. BMC Oral Health. 2023. 23 (1): 40.
2022年
▶︎原著論文
1. Aya Yamada, Keigo Yoshizaki, Kan Saito, Masaki Ishikawa, Yuta Chiba, Seira Hoshikawa, Mitsuki Chiba, Ryoko Hino, Yuriko Maruya, Hiroshi Sato, Keiji Masuda, Haruyoshi Yamaza, Takashi Nakamura, Tsutomu Iwamoto, Satoshi Fukumoto. GSK3beta inhibitor-induced dental mesenchymal stem cells regulate ameloblast differentiation. J Oral Biosci. 2022. 64(4):400-409.
2. Junichiro Wada, Kanae Wada, Mona Gibreel, Noriyuki Wakabayashi, Tsutomu Iwamoto, Pekka K. Vallittu, Lippo Lassila. Effect of Nitrogen Gas Post-Curing and Printer Type on the Mechanical Properties of 3D-Printed Hard Occlusal Splint Material. Polymers. 2022.14(19):3971.
3. Junichiro Wada, Kanae Wada, Mona Gibreel, Noriyuki Wakabayashi, Tsutomu Iwamoto, Pekka K. Vallittu, Lippo Lassila. Effect of 3D Printer Type and Use of Protection Gas during Post-Curing on Some Physical Properties of Soft Occlusal Splint Material. Polymers. 2022.14(21): 4618.
4. Tomoko Matsumura, Susumu Hosokawa, Miho Hanaoka, Yushi Abe, Tsutomu Iwamoto, Shigeru Maeda. Transient ventricular bigeminy during emergence from general anesthesia in a pediatric patient with catecholaminergic polymorphic ventricular tachycardia. J Electrocardiol. 2022.73: 38-41.
5. Yao Liu, Fumiya Kano, Noboru Hashimoto, Linze Xia, Qiao Zhou, Xingmei Feng, Hideharu Hibi, Aya Miyazaki, Tsutomu Iwamoto, Yoshizo Matsuka, Zhijun Zhang, Eiji Tanaka, Akihito Yamamoto. Conditioned Medium From the Stem Cells of Human Exfoliated Deciduous Teeth Ameliorates Neuropathic Pain in a Partial Sciatic Nerve Ligation Model. Front Pharmacol. 2022. 13:745020.
6. Tian Tian, Kanako Miyazaki, Yuta Chiba, Keita Funada, Tomomi Yuta, Kanji Mizuta, Yao Fu, Jumpei Kawahara, Xue Han, Yuna Ando, Ami Funada, Aya Yamada, Tsutomu Iwamoto, Seiji Nakamura, Ichiro Takahashi, Satoshi Fukumoto, Keigo Yoshizaki. An ex vivo organ culture screening model revealed that low temperature conditions prevent side effects of anticancer drugs. Sci Rep. 2022. 12(1):3093.
7. Hoshiai Aiko, Kusumoto Yasuka, Hoshiai Taiji, Kimura Naoki, Ito Yukiko, Yoshida Naomi, Shinozuka Osamu, Iwamoto Tsutomu. Factors Influencing Oral Hygiene Management in Patients with Rheumatoid Arthritis 障歯誌. 2022. 43(1):7-16.
8. Nakao Ryoma, Kobayashi Hirotaka, Iwabuchi Yusuke, Kawahara Kazuyoshi, Hirayama Satoru, Ramstedt Madeleine, Sasaki Yuki, Kataoka Michiyo, Akeda Yukihiro, Ohnishi Makoto. A highly immunogenic vaccine platform against encapsulated pathogens using chimeric probiotic Escherichia coli membrane vesicles. NPJ Vaccines. 2022.7(1):153
9. 黒厚子璃佳, 岩田こころ, 中川弘, 長谷川智一, 上田公子, 北村尚正, 赤澤友基, 杉本明日菜, 河原林啓太, 宮嵜 彩, 尼寺理恵, 藤島史帆, 岩崎智憲, 岩本 勉. 当科における 5 年間の障害児 · 有病児の初診時実態 調査．小児歯誌. 2022.02; 60(1); 20-27
▶︎症例報告
1. 金井恵未, 宮新美智世, 上原智己, 和田奏絵, 大石敦之, 長弘茂樹, 柿野聡子, 岩本勉. 歯頸部歯根破折を生じた下顎左側側切歯の 17 年後の経過を評価した 1 例 小児歯誌. 2022.11; 60(3); 141-147
▶︎総説
1. 黒厚子璃佳, 岩田こころ, 岩本 勉. 口腔機能の発達と育成．日本ヘルスケア歯科学会誌. 2022.12; 23(1); 17-23
2. 柿野聡子. 【歯と歯髄領域におけるレーザー · LED 応用の特色ある研究】LED を利用した歯髄血流測定による外傷歯の歯髄診断 日本レーザー医学会誌. 2022.07; 43(2); 91-97
2021年
▶︎原著論文
1. Kokoro Iwata, Keita Kawarabayashi, Keigo Yoshizaki, Tian Tian, Kan Saito, Asuna Sugimoto, Rika Kurogoushi, Aya Yamada, Akihito Yamamoto, Yasuei Kudo, Naozumi Ishimaru, Satoshi Fukumoto, Tsutomu Iwamoto. von Willebrand factor D and EGF domains regulate ameloblast differentiation and enamel formation. J Cell Physiol. 2021.237(3):1964-1979.
2. Yusuke Iwabuchi, Tomoyo Nakamura, Yasuka Kusumoto, Ryoma Nakao, Tsutomu Iwamoto, Osamu Shinozuka, Hidenobu Senpuku. Effects of pH on the Properties of Membrane Vesicles Including Glucosyltransferase in Streptococcus mutans. Microorganisms. 2021.9(11):2308.
3. Taki Sekiya, Kumiko Sugimoto, Ayako Kubota, Natsumi Tsuchihashi, Atsushi Oishi, Naomi Yoshida. Assessment of psychological changes in young children during dental treatment: Analysis of the autonomic nervous activity and electroencephalogram. Int J paediatr dent. 2021.32(3):418-427.
4. Aya Yamada, Keigo Yoshizaki, Masaki Ishikawa, Kan Saito, Yuta Chiba, Emiko Fukumoto, Ryoko Hino, Seria Hoshikawa, Mitsuki Chiba, Takashi Nakamura, Tsutomu Iwamoto, Satoshi Fukumoto. Connexin 43-Mediated Gap Junction Communication Regulates Ameloblast Differentiation via ERK1/2 Phosphorylation. Front Physiol. 2021.12:748574.
5. Rika Kurogoushi, Tomokazu Hasegawa, Yuki Akazawa, Kokoro Iwata, Asuna Sugimoto, Kimiko Yamaguchi-ueda, Aya Miyazaki, Anrizandy Narwidina, Keita Kawarabayashi, Takamasa Kitamura, Hiroshi Nakagawa, Tomonori Iwasaki, Tsutomu Iwamoto. Fibroblast growth factor 2 suppresses the expression of C-C motif chemokine 11 through the c-Jun N-terminal kinase pathway in human dental pulp-derived mesenchymal stem cells. Exp Ther Med. 2021. 22(6):1356.
6. Tamura Yukihiko, Fuangtharnthip Pornpoj, Uehara Tomoki, Iwamoto Tsutomu, Waki Yoshihiro. Metallothionein expression in zinc-treated cartilage precursor ATDC5 cells. Biomed Res Trace Elem. 2021. 32(1); 23-29.
7. Hideo Yonezawa, Mizuho Motegi, Atsushi Oishi,Fuhito Hojo, Seiya Higashi, Eriko Nozaki, Kentaro Oka, Motomichi Takahashi,Takako Osaki, Shigeru Kamiya. Lantibiotics Produced by Oral Inhabitants as a Trigger for Dysbiosis of Human Intestinal Microbiota. Int J Mol Sci. 2021. 22(7):3343.
8. Manami Takenoshita, Masaki Takechi (Co-first), Tri Vu Hoang, Toshiko Furutera, Chisaki Akagawa, Worachat Namangkalakul, Kazushi Aoto, Tsutomu Kume, Miciyo Miyashin, Tsutomu Iwamoto, Sachiko Iseki. Cell lineage- and expression-based inference of the roles of forkhead box transcription factor Foxc2 in craniofacial development. Dev Dyn. 2021.250(8):1125-1139.
▶︎症例報告
1. Yuko Seki, Tomoki Uehara, Miki Uehara, Haruko Fujita, Satoko Kakino, Michiyo Miyashin. Intentional replantation to the endodontic-periodontal disease associated with misplacement of a rubber band-like foreign body: A case report. Ped Dent J. 2021. 32(2):191-196.
2. Atsushi Oishi, Yohei Hama, Emi Kanai, Michiyo Miyashin. Color-changeable chewing gum to motivate chewing training with complete dentures for a male patient with hypohidrotic ectodermal dysplasia and oligodontia. Ped Dent J. 2021. 31(1):123-127.
2020年
▶︎原著論文
1. Shigeki Nagahiro, Tomoki Uehara, Mariko Yamamoto Kawai, Preksa Keo, Toshimi Sato, Hiroki Ochi, Shingo Sato, Shinji Kuroda, Takashi Ono, Michiyo Miyashin, Kazuhiro Aoki. RANKL-binding peptide promotes ectopic bone formation induced by BMP-2 gene transfer in murine gastrocnemius muscle. Dent Oral Maxillofac Res. 2020.6(1):1-6.
2. Komuro Hiroaki, Wint Wit Y., Horiuchi Naohiro, Nozaki Kosuke, Sasano Tetsuo, Miyashin Michiyo, Yamashita Kimihiro, Nagai Akiko. An oriented hydroxyapatite film with arrayed plate-like particles enhance chondrogenic differentiation of ATDC5 cells. J Biomed Mater Res A. 2020.108(3):537-544.
3. Keita Funada, Keigo Yoshizaki, Kanako MIyazaki, Xue Han, Tomomi Yuta, Tian Tian, Kanji Mizuta, Yao Fu, Tsutomu Iwamoto, Aya Yamada, Ichiro Takahashi, Satoshi Fukumoto. microRNA-875-5p plays critical role for mesenchymal condensation in epithelial-mesenchymal interaction during tooth development. Sci Rep. 2020.10(1):4918.
4. Tomoaki Nakamura, Tsutomu Iwamoto, Hannah M Nakamura, Yuki Shindo, Kan Saito, Aya Yamada, Yoshihiko Yamada, Satoshi Fukumoto, Takashi Nakamura. Regulation of miR-1-Mediated Connexin 43 Expression and Cell Proliferation in Dental Epithelial Cells. Front Cell Dev Biol. 2020.8:156.
5. Preksa Keo, Yoshiro Matsumoto, Yasuhiro Shimizu, Shigeki Nagahiro, Masaomi Ikeda, Kazuhiro Aoki, Takashi Ono. A pilot study to investigate the histomorphometric changes of murine maxillary bone around the site of mini-screw insertion in regenerated bone induced by anabolic reagents. Eur J Orthod. 2021.43(1):86-93.
6. N Ogasawara, F Kano, N Hashimoto, H Mori, Y Liu, L Xia, T Sakamaki, H Hibi, T Iwamoto, E Tanaka, A Yamamoto. Factors secreted from dental pulp stem cells show multifaceted benefits for treating experimental temporomandibular joint osteoarthritis. Osteoarthritis Cartilage. 2020. 28(6):831-841.
7. Keita Kawarabayashi, Fumiya Kano, Noboru Hashimoto, Hideharu Hibi, Tsuotmu Iwamoto, Akihihito Yamamoto. Conditioned Media from Human Dental Pulp Stem Cells Prevent Radiation-induced Skin Injury. J Oral Heal Biosci. 2020. 33(1):1-7.
8. Yuta Chiba, Keigo Yoshizaki, Kan Saito, Tomoko Ikeuchi, Tsutomu Iwamoto, Craig Rhodes, Takashi Nakamura, Susana de Vega, Robert J Morell, Erich T Boger, Daniel Martin, Ryoko Hino, Hiroyuki Inuzuka, Christopher K E Bleck, Aya Yamada, Yoshihiko Yamada, Satoshi Fukumoto. G-protein coupled receptor Gpr115 (Adgrf4) is required for enamel mineralization mediated by ameloblasts. J Biol Chem. 2020.295(45):15328-15341.
9. Ijbara Manhal, Wada Kanae, Wada Junichiro, Jayawardena Jayanetti Amiri, Miyashin Michiyo. Replica-based inspection of enamel wear microfeatures. Biomed Mater Eng. 2020.31(5):279-290.
10. Oo Thaw Dar, Satoko Kakino, Masahiko Kusano, Hideharu Ikeda, Michiyo Miyashin, Takashi Okiji. Transmitted-light plethysmography detects changes in human pulpal blood flow elicited by innocuous tooth cooling and foot heating. Arch Oral Biol. 2020.119:104881.
11. Tomoyo Nakamura, Yusuke Iwabuchi, Satoru Hirayama, Naoki Narisawa, Fumio Takenaga, Ryoma Nakao, Hidenobu Senpuku. Roles of membrane vesicles from Streptococcus mutans for the induction of antibodies to glucosyltransferase in mucosal immunity. Microb Pathog. 2020. 149:104260.
12. Ryoko Hino, Aya Yamada, Yuta Chiba, Keigo Yoshizaki, Emiko Fukumoto, Tsutomu Iwamoto, Yuriko Maruya, Keishi Otsu, Hidemistu Harada, Kan Saito, Satoshi Fukumoto. Melnick-Needles syndrome associated molecule, Filamin-A regulates dental epithelial cell migration and root formation. Ped Dent J. 2020.12; 30(3); 208-214.
▶︎症例報告
1. 星合愛子, 吉田直美, 星合泰治, 飯田敏朗, 足達淑子, 隅田由香, 篠塚 修. 歯科衛生過程を用いて問題解決に取り組んだ放射線治療後患者の1症例. 日歯衛誌. 2020.14(2): 93-101.
2. Kusumoto Yasuka, Imai Kohsuke, Ohyama Yoshio, Fukayama Haruhisa, Shinozuka Osamu. Oral management of a patient with down syndrome and agammaglobulinemia: a case report BMC Oral Health. 2020.20(1):71.
3. 黒厚子璃佳, 岩田こころ, 北村尚正, 松立吉弘, 藤田博己, 岩本 勉. 1 歳児の口蓋部に生じたマダニ刺咬症の1例．小児歯誌. 2020.58(3):166-172.
4. 岩田こころ, 黒厚子璃佳, 赤澤友基, 森 浩喜, 岩本 勉. 4歳6ヵ月男児の下顎左側乳犬歯早期脱落歯に対しての1考察. 小児歯誌. 2020. 58(3):204-211.
5. 杉本明日菜, 河原林啓太, 岩本 勉. 口腔機能発達不全を伴う空気嚥下症の児に対し、口腔筋機能療法 (MFT) が有効であった1例. 小児歯誌. 2020.58(3):195-203.
▶︎原著論文
1. Yuika Yamanaka, Kanae Wada, Shinya Oishi, Daiki Kondo, Yujeong Shin, Kaori Kohi, Misaki Hamashima,Asuna Sugimoto, Atsushi Oishi, Wataru Komada, Tsutomu Iwamoto. Effect of crown-core material combinations on cervical surface strain and of crown type on antagonist enamel wear in a simulated deciduous tooth model Dental Materials. 2025.10; 42(2); 219-226
2. Asuna Sugimoto, Kokoro Iwata, Rika Kurogoushi, Tsutomu Iwamoto. Successful correction of tooth eruption disturbance caused by mandibular enostosis using a pinhole perforation technique Pediatric Dental Journal. 2025.12; 35(3); 100365
3. Yumiko Nakashima, Kokoro Iwata, Asuna Sugimoto, Manami Tanaka, Muhammad Dhiaulfikri Nauval Hadiana, Nodoka Ato, Atsushi Oishi, Kanae Wada, Yuta Chiba, Triana Marchelina, Aya Yamada, Satoshi Fukumoto, Akihito Yamamoto, Tsutomu Iwamoto. Identification of a desmocollin 3-β-catenin complex modulated by Vwde-calpain signaling in ameloblast differentiation. Biochemical and Biophysical Research Communications. 2025.11; 792; 153000
4. Satoko Kakino, Hiroaki Ohki, Kaori Kohi, Yuko Matsumura, Tsutomu Iwamoto. Diagnostic accuracy of Transmitted-light plethysmography for the assessment of pulpal circulation in traumatized young permanent incisors Scientific Reports. 2025.11; 15; 42579
5. Triana Marchelina, Yuta Chiba, Shinji Otake, Li Wanshu, Hiroshi Sato, Yumiko Nakashima, Asuna Sugimoto, Tsutomu Iwamoto, Aya Yamada, Kan Saito, Satoshi Fukumoto. Expression patterns of desmosome family members during tooth development and the role of Desmocollin-3 in cytodifferentiation of stratum intermedium. Arch Oral Biol. 2025.09; 180; 106404
6. Kusumoto Yasuka, Iwabuchi Yusuke, Shindo Yuki, Sugimoto Asuna, Soma Chihiro, Watanabe Mayuko, Aida Takae, Iwamoto Tsutomu. Lower Lip Cellulitis Secondary to Apical Periodontitis in a Patient with Cerebral Palsy Associated with Intellectual Disability Journal of Oral Health and Biosciences. 2025.09; 38(1); 13-17
7. Kaori Kohi, Yumi Tsuchida, Kanae Wada, Yumiko Nakashima, Tsutomu Iwamoto, Hidekazu Takahashi. Machining accuracy of pediatric partial dentures using computer-aided design-computer aided manufacturing (CAD-CAM) system Journal of Clinical Pediatric Dentistry. 2025.06; 50(1); 103-113
8. Iwabuchi Y, Yoshida H, Kamei S, Uematsu T, Saito M, Senpuku H. Formation of Mono-Organismal and Mixed Staphylococcus aureus and Streptococcus mutans Biofilms in the Presence of NaCl. Microorganisms. 2025.05; 13(5);
9. Hiroaki Ohki, Satoko Kakino, Tsutomu Iwamoto. Evaluation of tooth-specific optical properties for the development of a non-invasive pulp diagnostic system using Transmitted-light plethysmography: An in vitro study. Archives of Oral Biology. 2025.04; Apr:172;
10. Kanae Wada, Sufyan Garoushi, Junichiro Wada, Tsutomu Iwamoto, Pekka K. Vallittu, Lippo Lassila. Mechanical and Structural Characterization of CAD-CAM Materials and Enamel of Deciduous and Permanent Teeth Dental Materials Journal. 2025.02; 44(2); 146-156
▶書籍等出版物
1. 和田 奏絵, 岩本 勉, 北村 和夫 他. 続・日常臨床のレベルアップ＆ヒント67選. デンタルダイヤモンド, 2025.04
▶総説
1. 杉本 明日菜. ピエゾ１機械受容チャネル（PIEZO1）による骨髄由来間葉系幹細胞における硬組織形成能の検討小児歯科学雑誌. 2025.02; 63(1); 1-4
▶講演・口頭発表等
1. Satoko Kakino, Yuko Matsumura, Taki Sekiya, Tsutomu Iwamoto. A case of intentional replantation of a young permanent incisor with pulp infection due to abnormal crown morphology and dental trauma.. The 11th Conference of Asian International Association of Dental Traumatology 2025.03.29 Held in journal
2. Satoko Kakino. Supporting Children with Cancer: Oral Care and Management of Oral Mucositis in a Hospital Setting.. International online conference on Children with Special health care needs. 2025.03.28
Online conference
3. Junichiro Wada, Kanae Wada, Pekka K. Vallittu, Lippo Lassila. Bacteria adhesion to additive-manufactured occlusal splint. 5th TCBC Midwinter Meeting 2025.02.12 Turku, Finland
1. 柿野 聡子. 歯· 口のけがとその対応—応急処置と経過観察の実際—. 町田市学校保健会小中合同養護部会 2025 年度歯科保健研修会2025.12.22 東京都町田市
2. 真藤 裕基, 中村 はな,中井 淳一,若森 実,中村 卓史. 唾液腺発生において神経制御下で機能する組織構築機構の解明. 第4回日本唾液ケア科学会学術集会2025.11.23
3. 柿野 聡子. 原発性免疫不全症候群の歯科的支援ー歯科治療と口腔粘膜炎のケアー. 2025年第1回医療講演会2025.11.16 東京
4. 内海 希、千葉 真子、脇田 亮、岩渕 佑介、真藤 祐基、楠本 康香、前田 茂. 知的能力障害を伴う病的肥満患者に対する全身麻酔下歯科治療の一例. 第42回日本障害者歯科学会2025.11.02大阪
5. 真藤 裕基, 相馬 千紘, 渡辺 真柚子, 岩淵 佑介, 大木 栞,楠本 康香,伊藤 孝哉,吉野 綾,石川 健太郎,前田 茂, 岩本 勉. ブラキシズムによる著しい咬合性外傷を認めたRett症候群の1症例. 第42回日本障害者歯科学会総会および学術大会2025.11.02
6. 柿野聡子, 田中眞実, 松村木綿子, 岩本 勉. 多発性歯内歯を認めた頭蓋外胚葉異形成症（Sensenbrenner症候群）に対し歯科的対応を行った1例. 第42回日本障害者歯科学会総会·学術大会2025.11.02大阪
7. 山内 英史,岩淵 佑介,鈴木 朋,内田 博之,北村 新,初野 有人,戸坂 清二,原田 達也,丸山 清孝,白井 弘三,新井 曄子, 時田 英紀,松本 勝洋,脇田 亮,篠塚 修. Rubinstein-Taybi症候群患者における長期口腔管理の1例. 第42回公益社団法人日本障害者歯科学会総会および学術大会2025.11.02 大阪
8. 相馬千紘,楠本 康香,岩淵 佑介,渡辺 真柚子,真藤 裕基,杉本 明日菜,平和田 智佳,岩本 勉. Fontan術後遠隔期の歯科治療の1例. 第42回日本障害者歯科学会総会および学術大会2025.11.02
9. 渡辺 真柚子,岩淵 佑介,星合 泰治,杉本 明日菜,真藤 裕基,平和田 智佳,楠本 康香,相田 貴絵,鈴木 朋,渡邊 麻里子,星合 愛子,相馬 千紘,岩本 勉. Fontan手術後遠隔期患者の歯科治療経験. 第42回日本障害者歯科学会総会および学術大会2025.11.02
10. 田中 眞実. 歯の発生メカニズムの解明および応用モデルの構築、日本障害者歯科学会. 2025.11.01 大阪
11. 新田 瑠璃子，柿野 聡子，歸山 えりか，松村 木綿子，岩本 勉. 舌下免疫療法中に浮腫性歯肉腫脹を認めた1例. 2025.10.05 東京
12. 浜島 美咲, 和田 奏絵, 小樋 香織, 山中 柚衣香,岩本 勉. デジタル口腔内スキャナーを活用した視覚的指導による口腔内情報の共有と支援アプローチ. 小児歯科学会第40回関東地方会大会·総会2025.10.05船堀
13. 中島 結美子, 岩田 こころ,杉本 明日菜,岩本 勉. 歯の発生過程におけるDesomocollin3の発現. 小児歯科学会第40 回関東地方会大会·総会2025.10.05 船堀
14. 中島 結美子,黒厚子 璃佳,岩田 こころ,杉本 明日菜,岩本 勉. 食生活調査票の記載から齲蝕重症度が評価できる.第72回日本小児保健協会学術集会2025.06.28 金沢
15. 武永 嶺, 柿野 聡子,松村 木綿子,平和田 智佳,岩本 勉. 脱落乳歯の再植部より歯冠の形態異常を伴う後継永久歯の早期萠出がみられた1例. 2025.05.30 新潟
16. 椿 礼子,大石 敦之,北市 裕大,岩淵 佑介,山中 柚衣香,杉本 明日菜,和田 奏絵,荒川 真一,岩本 勉. 新規根管洗浄液の探索における効果的な感染根管モデルの作製. 第63回日本小児歯科学会大会2025.05.29
17. 大石 敦之,北市 裕大,椿 礼子,岩淵 佑介,山中 柚衣香,杉本 明日菜,和田 奏絵,荒川 真一,岩本 勉. 高純度次亜塩素酸水の感染根管モデルを用いた抗菌·洗浄効果の検証. 第63回日本小児歯科学会大会2025.05.29新潟県新潟市
18. 加藤 音々、大石 敦之、杉本 明日菜、岩田 こころ、黒厚子 璃佳、内藤 悠、岩本 勉. 医科歯科連携の発展における医科棟手術室·病棟への可搬歯科ユニット実装過程. 第63回日本小児歯科学会大会2025.05.29新潟県新潟市
19. 内藤 悠, 松村 木綿子,和田 奏絵,岩本 勉. 第一大臼歯の遠心移動により,自然放出を認めた埋伏第二乳臼歯の１例. 第63回日本小児歯科学会大会2025.05.29 新潟県新潟市
20. 山中 柚衣香，和田 奏絵，Yujeong Shin，小樋 香織，浜島 美咲，杉本 明日菜，大石 敦之，岩本 勉. コア材料およびクラウン材料が乳臼歯歯頸部のひずみに及ぼす影響. 第63回日本小児歯科学会2025.05.29新潟県，新潟市
21. 大石 敦之. 小児患者における口腔外傷の初期対応. 日本外傷歯学会第15回 東日本地方会総会·学術大会教育講演 2025.05.25 埼玉県さいたま市
22. 関矢 多希、小樋 香織、柿野 聡子. 小児歯科専門医院における口腔外傷の実態調査. 第15回日本外傷歯学会東日本地方会学術大会2025.05.25 埼玉
23. 柿野 聡子. 子どもの口とケガ ～知っておきたい基本と応急処置～.. 東京都多摩立川保健所令和7年度保育園幼稚園歯科保健担当者研修会2025.05.23
24. 中島 結美子，黒厚子 璃佳，杉本 明日菜，岩田 こころ，岩本 勉. 平日·休日の起床および就寝時間のずれが齲蝕重症度と相関する. 第11回日本小児診療多職種研究会2025.03.08 広島
25. 真藤 裕基, 中村 卓史,楠本 康香,岩本 勉. 発生期唾液腺における副交感神経による筋上皮細胞の分化誘導機構の解明. 口腔病学会雑誌2025.03.01
▶受賞
1. Best presentation award (Division Excellence Awards-Pediatric Dentistry Division)：柿野 聡子, アジア外傷歯学会, 2025年03月
2. 大石 敦之：第63回日本小児歯科学会大会SHOFUAWARD（材料部門：高純度次亜塩素酸水の感染根管モデルを用いた抗菌·洗浄効果の検証）,日本小児歯科学会,2025年05月
3. 田中 眞実：第63回日本小児歯科学会大会：デンツプライシロナ賞,2025年05月
4. 中島 結美子：第72回日本小児保健協会学術集会 若手奨励賞,2025年06月
5. 日本障害者歯科学会 若手学術奨励賞：田中 眞実,2025年11月
6. 優秀論文賞：真藤 裕基,日本唾液ケア科学会,2025年11月
7. 日本障害者歯科学会若手学術奨励賞：岩淵 佑介,公益社団法人日本障害者歯科学会,2025年11月
2024年
▶︎原著論文
1. Junichiro Wada, Paulina Heponiemi, Kanae Wada, Sufyan Garoushi, Noriyuki Wakabayashi, Tsutomu Iwamoto, Pekka K. Vallittu, Lippo Lassila. Effect of ethylene oxide unit number in bis-EMA on the physical properties of additive-manufactured occlusal splint material. J Prosthodont Res. 2024.01.
2. Manami Tanaka, Asuna Sugimoto, Kokoro Iwata, Yumiko Nakashima, Muhammad Dhiaulfikri Nauval
Hadiana, Yusuke Iwabuchi, Kanae Wada, Atsushi Oishi, Tsutomu Iwamoto. Prrx2, the paired-related
homeobox transcription factor, functions as a potential regulator of pannexin 3 expression in odontoblast
differentiation. J Oral Biosci. 2024.12; 100601
3. Wada K, Wada J, Uctasli MB, Uctasli S, Yavuz Y, Iwamoto T, Vallittu PK, Garoushi S, Lassila L. Impact
of restorative material on fracture behaviors of class II restoration in endodontically treated deciduous
molars. Dental materials journal. 2024.08;
4. Wakita R, Kusumoto Y, Shinozuka O, Tokyo Metropolitan Hachinan Dental Association, Fukayama H,
Maeda S. Dental findings and intravenous sedation in a patient with Potocki-Lupski syndrome: A case
report. Special care in dentistry : official publication of the American Association of Hospital Dentists, the
Academy of Dentistry for the Handicapped, and the American Society for Geriatric Dentistry. 2024.05;
5. Lippo Lassila, Mine B. Uctasli, Kanae Wada, Pekka K. Vallittu, and Sufyan Garoushi. Effect of different
beverages and polishing techniques on colour stability of CAD/CAM composite restorative materials.
Biomaterial Investigations in Dentistry. 2024.04; 11; 34-41
▶︎症例報告
1. 高石和美、杉本明日菜、北村尚正、前尾 慶、藤原茂樹、西川美佳、藤田創詩、岩本 勉、川人 伸次. 先天性 QT 延長症候群3型患者に対し歯科治療時の全身管理を行った1例 2024.10; 45(3); 165-171
2. 柿野 聡子. 【外傷歯のアプローチ】初診時の診断と対応、予後の観察について 小児歯科臨床. 2024.06; 29(6);6-15
3. 倉重 圭史, 土岐 志麻, 鈴木 広幸, 田中 克明, 村井 雄司, 石通 宏行, 柿野 聡子, 桑原 康生, 近藤 有紀, 榊原 さや夏, 佐野 正之, 鈴木 淳司, 中村 由紀, 星川 聖良, 蓑輪 映里佳, 湯浅 健司, 苅部 洋行, 早崎 治明, 朝田 芳信,齊藤 正人. 口腔機能発達不全症の管理指導におけるオンライン診療に対する評価 小児歯科学雑誌. 2024.06; 62(2); 44-52
当分野の先生が受賞しました
【受賞】
1. 大石敦之:第 62 回日本小児歯科学会大会 優秀発表賞:根管洗浄における要時生成型二酸化塩素水溶液
(MA-T) の応用可能性の検証 , 2024 年 05 月
2. 杉本明日菜:日本小児歯科学会奨励賞, 日本小児歯科学会, 2024 年 05 月
3. 柿野聡子:Case Competition 1st Place, The 22nd World Congress on Dental Traumatology, 2024 年 07 月
4. 柿野聡子:QUINTESSENCE PUBLISHING Award, 2024 年 07 月
5. 田中 眞実:松風スチューデントアワード, 2024 年 10 月
▶︎原著論文
1. Asuna Sugimoto, Kokoro Iwata, Rika Kurogoushi, Manami Tanaka, Yumiko Nakashima, Yoshihito Yamakawa, Atsushi Oishi, Keigo Yoshizaki, Satoshi Fukumoto, Akihito Yamamoto, Naozumi Ishimaru, Tsutomu Iwamoto. C-terminus of PIEZO1 governs Ca2+ influx and intracellular ERK1/2 signaling pathway in mechanotransduction. Biochem Biophys Res Commun. 2023.682 39-45.
2. Junichiro Wada, Kanae Wada, Sadullah Uctasli, Noriyuki Wakabayashi, Tsutomu Iwamoto, Pekka K Vallittu, Lippo Lassila. Effect of splinting material type and location on resistance against deflection force of splinted periodontally compromised teeth with hypermobility. J Mech Behav Biomed Mater. 2023. 142 105873.
3. Yuta Chiba, Keigo Yoshizaki, Hiroshi Sato, Tomoko Ikeuchi, Craig Rhodes, Mitsuki Chiba, Kan Saito, Takashi Nakamura, Tsutomu Iwamoto, Aya Yamada, Yoshihiko Yamada, Satoshi Fukumoto. Deficiency of G protein-coupled receptor Gpr111/Adgrf2 causes enamel hypomineralization in mice by alteration of the expression of kallikrein-related peptidase 4 (Klk4) during pH cycling process. FASEB J. 2023. 37 (4): e22861.
4. Yao Fu, Kanako Miyazaki, Yuta Chiba, Keita Funada, Tomomi Yuta, Tian Tian, Kanji Mizuta, Jumpei Kawahara, Ling Zhang, Daniel Martin, Tsutomu Iwamoto, Ichiro Takahashi, Satoshi Fukumoto, Keigo Yoshizaki. Identification of GPI-anchored protein LYPD1 as an essential factor for odontoblast differentiation in tooth development. J Biol Chem. 2023.299(5):104638.
5. Junichiro Wada, Kanae Wada, Sufyan Garoushi, Akikazu Shinya, Noriyuki Wakabayashi, Tsutomu Iwamoto, Pekka K. Vallittu, Lippo Lassila. Effect of 3D printing system and post-curing atmosphere on micro- and nano-wear of additive-manufactured occlusal splint materials. J Mech Behav Biomed Mater. 2023. 142 105799.
6. Tomomi Yuta, Tian Tian, Yuta Chiba, Kanako Miyazaki, Keita Funada, Kanji Mizuta, Yao Fu, Jumpei Kawahara, Tsutomu Iwamoto, Ichiro Takahashi, Satoshi Fukumoto, Keigo Yoshizaki. Development of a novel ex vivo organ culture system to improve preservation methods of regenerative tissues. Sci Rep. 2023. 13 (1): 3354.
7. Anrizandy Narwidina, Aya Miyazaki, Kokoro Iwata, Rika Kurogoushi, Asuna Sugimoto, Yasusei Kudo, Keita Kawarabayashi, Yoshihito Yamakawa, Yuki Akazawa, Takamasa Kitamura, Hiroshi Nakagawa, Kimiko Yamaguchi-Ueda, Tomokazu Hasegawa, Keigo Yoshizaki, Satoshi Fukumoto, Akihito Yamamoto, Naozumi Ishimaru, Tomonori Iwasaki, Tsutomu Iwamoto. Iroquois homeobox 3 regulates odontoblast proliferation and differentiation mediated by Wnt5a expression. Biochem Biophys Res Commun. 2023. 650 47-54.
8. Yujeong Shin, Kanae Wada, Yumi,Tsuchida Manhal Ijbara, Masaomi Ikeda, Hidekazu Takahashi, Tsutomu Iwamoto. Wear behavior of materials for additive manufacturing after simulated occlusion of deciduous dentition. J Mech Behav Biomed Mater. 2023. 138 105627.
9. Fumiya Kano, Noboru Hashimoto, Yao Liu, Linze Xia, Takaaki Nishihara, Wakana Oki, Keita Kawarabayashi, Noriko Mizusawa, Keiko Aota, Takayoshi Sakai, Masayuki Azuma, Hideharu Hibi, Tomonori Iwasaki, Tsutomu Iwamoto, Nobuyasu Horimai, Akihito Yamamoto. Therapeutic benefits of factors derived from stem cells from human exfoliated deciduous teeth for radiation-induced mouse xerostomia. Sci Rep. 2023. 13 (1): 2706.
10. Zhao Li, Satoko Kakino, Tsutomu Iwamoto. A Characteristic Analysis of the Pulse Transit Time to Dental Pulp: An Attempt at a New Approach to Dental Pulp Diagnoses Based on the Microcirculatory System. J Oral Heal Biosci. 2023. 35 (2): 33-42.
11. Junichiro Wada, Kanae Wada, Mona Gibreel, Noriyuki Wakabayashi, Tsutomu Iwamoto, Pekka K Vallittu, Lippo Lassila. Effect of Surface Polishing on Physical Properties of an Occlusal Splint Material for Additive Manufacturing under Protection Gas Post-Curing Condition. Polymers. 2023.1 (3): 625.
12. Kanae Wada, Manhal Ijbara, Nesreen A Salim, Junichiro Wada, Tsutomu Iwamoto. Three-dimensional microscopic comparison of wear behavior between immature and mature enamel: an in vitro study. BMC Oral Health. 2023. 23 (1): 40.
2022年
▶︎原著論文
1. Aya Yamada, Keigo Yoshizaki, Kan Saito, Masaki Ishikawa, Yuta Chiba, Seira Hoshikawa, Mitsuki Chiba, Ryoko Hino, Yuriko Maruya, Hiroshi Sato, Keiji Masuda, Haruyoshi Yamaza, Takashi Nakamura, Tsutomu Iwamoto, Satoshi Fukumoto. GSK3beta inhibitor-induced dental mesenchymal stem cells regulate ameloblast differentiation. J Oral Biosci. 2022. 64(4):400-409.
2. Junichiro Wada, Kanae Wada, Mona Gibreel, Noriyuki Wakabayashi, Tsutomu Iwamoto, Pekka K. Vallittu, Lippo Lassila. Effect of Nitrogen Gas Post-Curing and Printer Type on the Mechanical Properties of 3D-Printed Hard Occlusal Splint Material. Polymers. 2022.14(19):3971.
3. Junichiro Wada, Kanae Wada, Mona Gibreel, Noriyuki Wakabayashi, Tsutomu Iwamoto, Pekka K. Vallittu, Lippo Lassila. Effect of 3D Printer Type and Use of Protection Gas during Post-Curing on Some Physical Properties of Soft Occlusal Splint Material. Polymers. 2022.14(21): 4618.
4. Tomoko Matsumura, Susumu Hosokawa, Miho Hanaoka, Yushi Abe, Tsutomu Iwamoto, Shigeru Maeda. Transient ventricular bigeminy during emergence from general anesthesia in a pediatric patient with catecholaminergic polymorphic ventricular tachycardia. J Electrocardiol. 2022.73: 38-41.
5. Yao Liu, Fumiya Kano, Noboru Hashimoto, Linze Xia, Qiao Zhou, Xingmei Feng, Hideharu Hibi, Aya Miyazaki, Tsutomu Iwamoto, Yoshizo Matsuka, Zhijun Zhang, Eiji Tanaka, Akihito Yamamoto. Conditioned Medium From the Stem Cells of Human Exfoliated Deciduous Teeth Ameliorates Neuropathic Pain in a Partial Sciatic Nerve Ligation Model. Front Pharmacol. 2022. 13:745020.
6. Tian Tian, Kanako Miyazaki, Yuta Chiba, Keita Funada, Tomomi Yuta, Kanji Mizuta, Yao Fu, Jumpei Kawahara, Xue Han, Yuna Ando, Ami Funada, Aya Yamada, Tsutomu Iwamoto, Seiji Nakamura, Ichiro Takahashi, Satoshi Fukumoto, Keigo Yoshizaki. An ex vivo organ culture screening model revealed that low temperature conditions prevent side effects of anticancer drugs. Sci Rep. 2022. 12(1):3093.
7. Hoshiai Aiko, Kusumoto Yasuka, Hoshiai Taiji, Kimura Naoki, Ito Yukiko, Yoshida Naomi, Shinozuka Osamu, Iwamoto Tsutomu. Factors Influencing Oral Hygiene Management in Patients with Rheumatoid Arthritis 障歯誌. 2022. 43(1):7-16.
8. Nakao Ryoma, Kobayashi Hirotaka, Iwabuchi Yusuke, Kawahara Kazuyoshi, Hirayama Satoru, Ramstedt Madeleine, Sasaki Yuki, Kataoka Michiyo, Akeda Yukihiro, Ohnishi Makoto. A highly immunogenic vaccine platform against encapsulated pathogens using chimeric probiotic Escherichia coli membrane vesicles. NPJ Vaccines. 2022.7(1):153
9. 黒厚子璃佳, 岩田こころ, 中川弘, 長谷川智一, 上田公子, 北村尚正, 赤澤友基, 杉本明日菜, 河原林啓太, 宮嵜 彩, 尼寺理恵, 藤島史帆, 岩崎智憲, 岩本 勉. 当科における 5 年間の障害児 · 有病児の初診時実態 調査．小児歯誌. 2022.02; 60(1); 20-27
▶︎症例報告
1. 金井恵未, 宮新美智世, 上原智己, 和田奏絵, 大石敦之, 長弘茂樹, 柿野聡子, 岩本勉. 歯頸部歯根破折を生じた下顎左側側切歯の 17 年後の経過を評価した 1 例 小児歯誌. 2022.11; 60(3); 141-147
▶︎総説
1. 黒厚子璃佳, 岩田こころ, 岩本 勉. 口腔機能の発達と育成．日本ヘルスケア歯科学会誌. 2022.12; 23(1); 17-23
2. 柿野聡子. 【歯と歯髄領域におけるレーザー · LED 応用の特色ある研究】LED を利用した歯髄血流測定による外傷歯の歯髄診断 日本レーザー医学会誌. 2022.07; 43(2); 91-97
2021年
▶︎原著論文
1. Kokoro Iwata, Keita Kawarabayashi, Keigo Yoshizaki, Tian Tian, Kan Saito, Asuna Sugimoto, Rika Kurogoushi, Aya Yamada, Akihito Yamamoto, Yasuei Kudo, Naozumi Ishimaru, Satoshi Fukumoto, Tsutomu Iwamoto. von Willebrand factor D and EGF domains regulate ameloblast differentiation and enamel formation. J Cell Physiol. 2021.237(3):1964-1979.
2. Yusuke Iwabuchi, Tomoyo Nakamura, Yasuka Kusumoto, Ryoma Nakao, Tsutomu Iwamoto, Osamu Shinozuka, Hidenobu Senpuku. Effects of pH on the Properties of Membrane Vesicles Including Glucosyltransferase in Streptococcus mutans. Microorganisms. 2021.9(11):2308.
3. Taki Sekiya, Kumiko Sugimoto, Ayako Kubota, Natsumi Tsuchihashi, Atsushi Oishi, Naomi Yoshida. Assessment of psychological changes in young children during dental treatment: Analysis of the autonomic nervous activity and electroencephalogram. Int J paediatr dent. 2021.32(3):418-427.
4. Aya Yamada, Keigo Yoshizaki, Masaki Ishikawa, Kan Saito, Yuta Chiba, Emiko Fukumoto, Ryoko Hino, Seria Hoshikawa, Mitsuki Chiba, Takashi Nakamura, Tsutomu Iwamoto, Satoshi Fukumoto. Connexin 43-Mediated Gap Junction Communication Regulates Ameloblast Differentiation via ERK1/2 Phosphorylation. Front Physiol. 2021.12:748574.
5. Rika Kurogoushi, Tomokazu Hasegawa, Yuki Akazawa, Kokoro Iwata, Asuna Sugimoto, Kimiko Yamaguchi-ueda, Aya Miyazaki, Anrizandy Narwidina, Keita Kawarabayashi, Takamasa Kitamura, Hiroshi Nakagawa, Tomonori Iwasaki, Tsutomu Iwamoto. Fibroblast growth factor 2 suppresses the expression of C-C motif chemokine 11 through the c-Jun N-terminal kinase pathway in human dental pulp-derived mesenchymal stem cells. Exp Ther Med. 2021. 22(6):1356.
6. Tamura Yukihiko, Fuangtharnthip Pornpoj, Uehara Tomoki, Iwamoto Tsutomu, Waki Yoshihiro. Metallothionein expression in zinc-treated cartilage precursor ATDC5 cells. Biomed Res Trace Elem. 2021. 32(1); 23-29.
7. Hideo Yonezawa, Mizuho Motegi, Atsushi Oishi,Fuhito Hojo, Seiya Higashi, Eriko Nozaki, Kentaro Oka, Motomichi Takahashi,Takako Osaki, Shigeru Kamiya. Lantibiotics Produced by Oral Inhabitants as a Trigger for Dysbiosis of Human Intestinal Microbiota. Int J Mol Sci. 2021. 22(7):3343.
8. Manami Takenoshita, Masaki Takechi (Co-first), Tri Vu Hoang, Toshiko Furutera, Chisaki Akagawa, Worachat Namangkalakul, Kazushi Aoto, Tsutomu Kume, Miciyo Miyashin, Tsutomu Iwamoto, Sachiko Iseki. Cell lineage- and expression-based inference of the roles of forkhead box transcription factor Foxc2 in craniofacial development. Dev Dyn. 2021.250(8):1125-1139.
▶︎症例報告
1. Yuko Seki, Tomoki Uehara, Miki Uehara, Haruko Fujita, Satoko Kakino, Michiyo Miyashin. Intentional replantation to the endodontic-periodontal disease associated with misplacement of a rubber band-like foreign body: A case report. Ped Dent J. 2021. 32(2):191-196.
2. Atsushi Oishi, Yohei Hama, Emi Kanai, Michiyo Miyashin. Color-changeable chewing gum to motivate chewing training with complete dentures for a male patient with hypohidrotic ectodermal dysplasia and oligodontia. Ped Dent J. 2021. 31(1):123-127.
2020年
▶︎原著論文
1. Shigeki Nagahiro, Tomoki Uehara, Mariko Yamamoto Kawai, Preksa Keo, Toshimi Sato, Hiroki Ochi, Shingo Sato, Shinji Kuroda, Takashi Ono, Michiyo Miyashin, Kazuhiro Aoki. RANKL-binding peptide promotes ectopic bone formation induced by BMP-2 gene transfer in murine gastrocnemius muscle. Dent Oral Maxillofac Res. 2020.6(1):1-6.
2. Komuro Hiroaki, Wint Wit Y., Horiuchi Naohiro, Nozaki Kosuke, Sasano Tetsuo, Miyashin Michiyo, Yamashita Kimihiro, Nagai Akiko. An oriented hydroxyapatite film with arrayed plate-like particles enhance chondrogenic differentiation of ATDC5 cells. J Biomed Mater Res A. 2020.108(3):537-544.
3. Keita Funada, Keigo Yoshizaki, Kanako MIyazaki, Xue Han, Tomomi Yuta, Tian Tian, Kanji Mizuta, Yao Fu, Tsutomu Iwamoto, Aya Yamada, Ichiro Takahashi, Satoshi Fukumoto. microRNA-875-5p plays critical role for mesenchymal condensation in epithelial-mesenchymal interaction during tooth development. Sci Rep. 2020.10(1):4918.
4. Tomoaki Nakamura, Tsutomu Iwamoto, Hannah M Nakamura, Yuki Shindo, Kan Saito, Aya Yamada, Yoshihiko Yamada, Satoshi Fukumoto, Takashi Nakamura. Regulation of miR-1-Mediated Connexin 43 Expression and Cell Proliferation in Dental Epithelial Cells. Front Cell Dev Biol. 2020.8:156.
5. Preksa Keo, Yoshiro Matsumoto, Yasuhiro Shimizu, Shigeki Nagahiro, Masaomi Ikeda, Kazuhiro Aoki, Takashi Ono. A pilot study to investigate the histomorphometric changes of murine maxillary bone around the site of mini-screw insertion in regenerated bone induced by anabolic reagents. Eur J Orthod. 2021.43(1):86-93.
6. N Ogasawara, F Kano, N Hashimoto, H Mori, Y Liu, L Xia, T Sakamaki, H Hibi, T Iwamoto, E Tanaka, A Yamamoto. Factors secreted from dental pulp stem cells show multifaceted benefits for treating experimental temporomandibular joint osteoarthritis. Osteoarthritis Cartilage. 2020. 28(6):831-841.
7. Keita Kawarabayashi, Fumiya Kano, Noboru Hashimoto, Hideharu Hibi, Tsuotmu Iwamoto, Akihihito Yamamoto. Conditioned Media from Human Dental Pulp Stem Cells Prevent Radiation-induced Skin Injury. J Oral Heal Biosci. 2020. 33(1):1-7.
8. Yuta Chiba, Keigo Yoshizaki, Kan Saito, Tomoko Ikeuchi, Tsutomu Iwamoto, Craig Rhodes, Takashi Nakamura, Susana de Vega, Robert J Morell, Erich T Boger, Daniel Martin, Ryoko Hino, Hiroyuki Inuzuka, Christopher K E Bleck, Aya Yamada, Yoshihiko Yamada, Satoshi Fukumoto. G-protein coupled receptor Gpr115 (Adgrf4) is required for enamel mineralization mediated by ameloblasts. J Biol Chem. 2020.295(45):15328-15341.
9. Ijbara Manhal, Wada Kanae, Wada Junichiro, Jayawardena Jayanetti Amiri, Miyashin Michiyo. Replica-based inspection of enamel wear microfeatures. Biomed Mater Eng. 2020.31(5):279-290.
10. Oo Thaw Dar, Satoko Kakino, Masahiko Kusano, Hideharu Ikeda, Michiyo Miyashin, Takashi Okiji. Transmitted-light plethysmography detects changes in human pulpal blood flow elicited by innocuous tooth cooling and foot heating. Arch Oral Biol. 2020.119:104881.
11. Tomoyo Nakamura, Yusuke Iwabuchi, Satoru Hirayama, Naoki Narisawa, Fumio Takenaga, Ryoma Nakao, Hidenobu Senpuku. Roles of membrane vesicles from Streptococcus mutans for the induction of antibodies to glucosyltransferase in mucosal immunity. Microb Pathog. 2020. 149:104260.
12. Ryoko Hino, Aya Yamada, Yuta Chiba, Keigo Yoshizaki, Emiko Fukumoto, Tsutomu Iwamoto, Yuriko Maruya, Keishi Otsu, Hidemistu Harada, Kan Saito, Satoshi Fukumoto. Melnick-Needles syndrome associated molecule, Filamin-A regulates dental epithelial cell migration and root formation. Ped Dent J. 2020.12; 30(3); 208-214.
▶︎症例報告
1. 星合愛子, 吉田直美, 星合泰治, 飯田敏朗, 足達淑子, 隅田由香, 篠塚 修. 歯科衛生過程を用いて問題解決に取り組んだ放射線治療後患者の1症例. 日歯衛誌. 2020.14(2): 93-101.
2. Kusumoto Yasuka, Imai Kohsuke, Ohyama Yoshio, Fukayama Haruhisa, Shinozuka Osamu. Oral management of a patient with down syndrome and agammaglobulinemia: a case report BMC Oral Health. 2020.20(1):71.
3. 黒厚子璃佳, 岩田こころ, 北村尚正, 松立吉弘, 藤田博己, 岩本 勉. 1 歳児の口蓋部に生じたマダニ刺咬症の1例．小児歯誌. 2020.58(3):166-172.
4. 岩田こころ, 黒厚子璃佳, 赤澤友基, 森 浩喜, 岩本 勉. 4歳6ヵ月男児の下顎左側乳犬歯早期脱落歯に対しての1考察. 小児歯誌. 2020. 58(3):204-211.
5. 杉本明日菜, 河原林啓太, 岩本 勉. 口腔機能発達不全を伴う空気嚥下症の児に対し、口腔筋機能療法 (MFT) が有効であった1例. 小児歯誌. 2020.58(3):195-203.