論文

Kudo　T, Ikeda M, Nishikawa M, Yang Z, Ohno K, Nakagawa K, Hata Y. The RASSF3 candidate tumor suppressor induces apoptosis and G1/S cell cycle arrest via p53. Cancer Res. In press.

Withanage K, Nakagawa K, Ikeda M, Kurihahara H, Kudo T, Yang Z, Sakanae A, Sasaki T, Hata Y. Expression of RASSF6 in kidney and the implication of RASSF6 and the Hippo pathway in the sorbitol-induced apoptosis in renal proximal tubular epithelial cells. J. Biochem. In press.

Hirai S, Miwa A, Ohtaka-Maruyama C, Kasai M, Okabe S, Hata Y, Okado H. RP58 controls neuron and astrocyte differentiation by downregulating the expression of Id1-4 genes in the developing cortex. EMBO J. 2012 Jan 10;31(5):1190-202

Bao Y, Nakagawa K, Yang Z, Ikeda M, Withanage K, Ishigami-Yuasa M, Okuno Y, Hata S, Nishina H, Hata Y. A cell-based assay to screen stimulators of the Hippo pathway reveals the inhibitory effect of dobutamine on the YAP-dependent gene transcription. J. Biochem. 150, 199-208. 2011.

Bao Y, Hata Y, Ikeda M, Withanage K. Mammlian Hippo pathway:from development to cancer and beyond. J. Biochem. 149, 361-379. 2011

Fukaya M, Kamata A, Hara Y, Tamaki H, Katsumata O, Ito N, Takeda S, Hata Y, Suzuki T, Watanabe M, Harvey RJ, Sakagami H. SynArfGEF is a guanine nucleotide exchange factor for Arf6 and localizes preferentially at post-synaptic specializations of inhibitory synapse. J. Neurochem. 116, 1122-1137. 2011.

Kaufman L, Potla U, Coleman S, Dikiy S, Hata Y, Kurihara H, He JC, D’Agati VD, Klotman PE. Upregulation of the homophilic adhesion molecule Sidekick-1 in podocytes contributes to glomeruloscrelosis. J. Biol. Chem.285, 25677-25685. 2010.

Nakagawa K, Sugahara M, Yamasaki T, Kajiho H, Takahashi S, Hirayama J, Minami Y, Ohta Y, Watanabe T, Hata Y, Katada T, Nishina H. Filamin associates with stress signaling kinases MKK7 and MKK4 and regulates JNK activation. Biochem. J. 427(2), 237-245. 2010.

Bao Y, Sumita K, Kudo T, Withanage K, Nakagawa K, Ikeda M, Ohno K, Wang Y, Hata Y. Roles of mammalian sterile 20-like kinase 2-dependent phosphorylations of Mps one binder 1B in the activation of nuclear Dbf2-related kinases. Genes Cells 14: 1369-1381. 2009.

Ikeda M, Kawata A, Nishikawa M, Tateishi Y, Yamaguchi M, Nakagawa K, Hirabayashi S, Bao Y, Hidaka S, Hirata Y, Hata Y. Hippo pathway-dependent and -independent roles of RASSF6. Sci. Signal. 2: ra59 2009.

Hirabayashi S, Nakagawa K, Sumita K, Hidaka S, Kawai T, Ikeda M, Kawata A, Ohno K, Hata Y. Threonine 74 of MOB1 is a putative key phosphorylation site by MST2 to form the scaffold to activate nuclear Dbf2-related kinase 1. Oncogene 27: 4281-4292. 2008.

Takahashi A, Hirai S, Ohtaka-Maruyama C, Miwa A, Hata Y, Okabe S, Okado H. Co-localization of a novel transcriptional repressor simiRP58 with RP58. Biochem. Biophys. Res. Commun. 368: 637-642. 2008.

Iida J, Ishizaki H, Okamoto-Tanaka M, Kawata A, Sumita K, Ohgake S, Sato Y, Yorifuji H, Nukina,N, Ohashi K, Mizuno K, Tsutsumi T, Mizoguchi A, Miyoshi J, Takai Y, Hata Y. S-SCAMalpha is a scaffold to mediate NMDA receptor-dependent RhoA activation in dendrites. Mol. Cell. Biol. 27: 4388-4405. 2007.

Ikeda M, Hirabayashi S, Fujiwara N, Mori H, Kawata A, Iida J, Bao Y, Sato Y, Iida T, Sugimura H, Hata Y. Ras-association domain family protein 6 induces apoptosis via both caspase-dependent and caspase-independent pathways. Exp. Cell Res. 313: 1484-1495. 2007.

Sumita K, Sato Y, Iida J, Kawata A, Hamano M, Hirabayashi S, Ohno K, Peles E, Hata Y. S-SCAM/MAGI-2 is associated with cell adhesion molecules at inhibitory synapses at rat hippocampal, neurons. J. Neurochem. 100: 154-166. 2007.

Fujiwara N, Ikeda M Hirabayashi S, Mori H, Shirasawa M, Kansaku A, Sunamori M, Hata Y. Monoclonal antibody 7F9 recognizes rat protein homologous to human carboxypeptidase-M in rat developing and adult lung. Respirology 12: 54-62. 2007.

Nagamatsu G, Ohmura M, Mizukami T, Hamaguchi I, Hirabayashi S, Yoshida S, Hata Y, Suda T, Ohbo K. CTX family cell adhesion molecule, JAM4, expresses in stem cell- and progenitor cell populations of both male germ cell and hematopoietic cell lineages. Mol. Cell. Biol. 24: 8498-8506. 2006.

Kansaku A, Hirabayashi S, Mori H, Fujiwara N, Kawata A, Ikeda M, Rokukawa C, Kurihara H, Hata Y. Ligand-of-Numb protein X is an endocytic scaffold for junctional adhesion molecule 4. Oncogene 25: 5071-5084. 2006.

Kawata A, Iida J, Ikeda M, Sato Y, Mori H, Kansaku A, Sumita K, Fujiwara N, Rokukawa C, Hamano M, Hirabayashi S, Hata Y. CIN85 is localized at synapses and forms a complex with S-SCAM via Dendrin. J. Biochem. 139: 931-939. 2006.

Uchida T, Shirasawa M, Ware LB, Kojima K, Hata Y, Makita K, Mednick G, Matthay ZA, Matthay MA. Receptor for advanced glycation end-products is a marker of type I cell injury in acute lung injury. Am. J. Respir. Crit. Care Med. 173: 1008-1015. 2006.

Hirabayashi S, Mori H, Kansaku A, Sakai H, Shimizu F, Kawachi H, Hata Y. MAGI-1 is a component of the glomerular slit diaphragm that is tightly associated with nephrin. Lab. Invest. 85: 1528-1543. 2005.