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TMDU: Did you know...?
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TMDU Research Activities
TMDU Research Activities 2020
TMDU: Did you know...?
TMDU: Did you know...?
TMDU Research Activities
TMDU Research Activities 2023-2024
TMDU Research Activities 2023-2024
TMDU Center for Infectious Disease Education and Analysis (TCIDEA) by Yoshiaki Gu, Tomoko Yazawa and Hiroaki Takeuchi
Successful murine model of dermatomyositis reveals underlying immune system involvement by Naoko Okiyama
Informatics and Artificial Intelligence for Biomedicine -Present and the Next Generation- by Yoshikazu Nakajima
The hidden identity of leukemia by Masatoshi Takagi and Akira Nishimura
CiDRE renders alveolar macrophages susceptible to SARS-CoV-2 invasion by Takashi Satoh and Yuichi Mitsui
Towards a Better Understanding of Endothelial Cell Transformation in Cancer Progression by Tetsuro Watabe, Miho Kobayashi and Kazuki Takahashi
Self vs Non-self discrimination in antiviral immune response by Kazuki Kato
Breaking through barriers by Hirokazu Kaji and Takeshi Hori
A secret passage for mutant protein to invade the brain by Hitoshi Okazawa
Link between chronic kidney disease and cardiovascular disease explained by Shintaro Mandai
Deciphering the Secrets of Brain Development by Naofumi Uesaka
Placenta transmits parental information to offspring by Joji Kusuyama
The “Wishbone” Charm that Restores the Hope for Bone Regeneration by Takashi Ono and Yuji Ishida
Protein Secrets Unveiled: New molecular insight of protein–protein interactions by Miki Hara-Yokoyama
New insights into the development of Parkinson’s disease in the brain by Satoru Torii
Toward understanding mechanisms of chronic inflammation by Yumiko Oishi
Can ChatGPT diagnose your condition? Not yet by Koji Fujita
Nano Drug Delivery System (DDS) for mRNA Therapeutics by Satoshi Uchida
Killer smile? An oral pathogen increases heart attack damage by Yasuhiro Maejima
A new, promising weapon in the fight against HIV by Hirokazu Tamamura
Pre-basophils: a basophil origin story by Kensuke Miyake
A new mechanism encouraging the brain to self-repair after an ischemic stroke by Takashi Shichita
TMDU Research Activities 2022-2023
TMDU Research Activities 2022-2023
Stopping the spread: targeting tumor metastasis by Tetsuro Watabe, Katarzyna A. Podyma-Inoue and Kazuki Takahashi
Tears in Tokyo: Muscle–tendon injuries during Olympic competition can spell heartbreak by Hideyuki Koga
Evidence showing the ‘loosening of associations’ found in schizophrenia by Hidehiko Takahashi
Toward understanding diversity of various disorder-specific myeloid cells by Takashi Satoh
Body versus brain: New evidence for an autoimmune cause of schizophrenia by Hiroki Shiwaku
From grave to cradle: collagen-induced gut cell reprogramming by Shiro Yui and Sakurako Kobayashi
Biomolecular Analyses Now Have an Expanded Chemical Toolkit by Yuki Sakata
The world’s first Mini Organ transplantation to a patient with “Ulcerative Colitis (UC)” by Ryuichi Okamoto, Tomohiro Mizutani and Hiromichi Shimizu
Biochemistry and molecular genetics to understand life and diseases by Katsumori Segawa
Filling the Gap Between Benchside and Bedside: AI-accelerated Target Discovery to Therapeutic Development by Hideyuki Shimizu
Minimally Invasive Drug and Cell Delivery Systems Targeting the Posterior Segment of the Eye by Hirokazu Kaji
Molecular mechanisms underlying hereditary Parkinson's disease by Noriyuki Matsuda
Building Better Gas-phase Biosensors for Fight Against Diseases by Kenta Iitani
Mind your Qs: polyQ-binding protein 5 scaffolds the nucleolus by Hitoshi Okazawa
Expanding the arsenal of drugs against COVID-19 by Hirokazu Tamamura
A novel drug suppresses muscle inflammation and restores muscle weakness by Shinsuke Yasuda and Mari Kamiya
Move over muscles, it’s time for tendons to be in the spotlight by Hiroshi Asahara and Ryo Nakamichi
Xanthan gum-based fluid thickener can help decrease blood glucose levels by Haruka Tohara, Sayaka Katagiri and Yuuki Nagasawa
Precision Engineering Design for Biofunctional Repair and Support by Masashi Ikeuchi
A Matter of Concentration: Molecular Mechanisms of Water Homeostasis by Fumiaki Ando
Clinical application of the digital dentures by Manabu Kanazawa
Transistors help identify cancer cell markers by Yuji Miyahara
Dental OCT - A Novel Imaging Technique without the use of X rays by Yasushi Shimada
TMDU Research Activities 2021-2022
TMDU Research Activities 2021-2022
Periodontal Regeneration with Cell Sheet Technology by Takanori Iwata
Targeting Necroptosis for Inflammatory Myopathies by Shinsuke Yasuda & Mari Kamiya
Seeing Lipids More Deeply with Mass Spectrometry by Takehiko Sasaki & Shin Morioka
Predicting the Progression of Rheumatoid Arthritis by Yuta Kochi
Drilling into the Dental Secrets of Edo-era Japanese Bacterial Genomes by Takeaki Sudo & Takahiko Shiba
When mad AIOLOS drags IKAROS down: a novel pathogenic mechanism by Tomohiro Morio & Motoi Yamashita
Osteoarthritis of the knee is evaluated with 3DMRI and regenerated with stem cells by Ichiro Sekiya
Pathologic myopia - The major cause of visual impairment by Kyoko Ohno-Matsui
Infusion of 3D cellular structures might repair damaged intestine by Shiro Yui & Satoshi Watanabe
Machine learning to synthesize endoscopy findings in ulcerative colitis by Kento Takenaka
“On-skin-pancreas” technology for precision medicine in diabetes by Akira Matsumoto
Ventilating the rectum to support respiration by Takanori Takebe
Prediction and detection of atrial fibrillation for reducing cardiogenic stroke by Tetsuo Sasano
Social pathways between oral and general health by Jun Aida
No IgA leads to intestinal inflammation in mice by Takahiro Adachi
A new agent for the brain diseases: mRNA by Keiji Itaka & Yuta Fukushima
Getting You Moving Again: A Possible New Treatment for Joint Issues by Hiroshi Asahara & Yoshiaki Ito
One protein to rule them all: a central target for treating dementia by Hitoshi Okazawa & Hikari Tanaka
Jigsaw-Shaped Peptide Solves Tissue Regeneration Puzzle by Itsuki Ajioka
The Xa Factor : Pushing Back on Atherosclerosis by Yasuhiro Maejima
Restoring healthy gut bacteria through blood stem cell transplantation by Hirokazu Kanegane
A new polarized fluorescent probe for revealing architectural dynamics of living cells by Sumio Terada, Keisuke Sato & Ayana Sugizaki
Genetic variant linked to prognosis of chronic hypersensitivity pneumonitis by Yasunari Miyazaki
Super-Enhancers: The Villain Fueling Certain Cancers by Johji Inazawa & Yasuyuki Gen
Bringing cells closer to form new tissues by Nobuhiko Yui
Lighting the LAMP to Reveal Mystery of Lysosomes by Miki Hara-Yokoyama
HIV has been Had by Hirokazu Tamamura
Using Mice to Open the Way to Prevent Blocked Arteries by Masayuki Yoshida
TMDU Research Activities 2020-2021
TMDU Research Activities 2020-2021
Message from the President – 3 Policies of TMDU Research
“My Medicine” with organoids– Predicting the future of liver-safe drugs
Nothing but the Truth in the Fight Against Cancer
How Cells Decide the Way They Want to Recycle Their Content
Generation of three-dimensional heart organoids
Message from the Executive Director (Research)
Introducing the M&D Data Science Center - A center of gravity for biomedical data science in the world
How poor oral hygiene may result in metabolic syndrome
β-AR Agonist Therapy Puts the Brakes on Oral Cancer Progression
The natural artistry of disease: a wintry landscape in the eye
Reversible Stickiness is Something to Smile About
A new molecular guardian of intestinal stem cells
Human Lifelong Immunity Depends on APRIL
From blood to brain: delivering nucleic acid therapy to the CNS
TMDU Research Activities 2020
TMDU Research Activities 2020
History and Location of TMDU
TMDU Research NEWS
Research at TMDU - Prominent Researcher
TMDU's International Collaboration & Education
TMDU: Did you know...?
TMDU Research Activities 2019
TMDU Research Activities 2019
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Prominent Researcher
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Features of TMDU Research
Self-organization of vascularized organoids allows enhanced survival of islet transplants for use in diabetes therapy
Studying hair follicle loss as a model of age-related organ decline
Out with the old, in with the new: Stem cell therapy for inflammatory bowel disease (IBD)
Immune checkpoints in T cell-mediated tissue inflammation
Controlling multipotent stem cell differentiation with molecularly-tuned movable surfaces
Innovative Researchers
Innovative Researchers
IBD, and beyond: Extracellular matrix dictates cell fate transition during inflammation
Budding Researchers
Budding Researchers
Physiological and environmental biosensing for preemptive and preventive medicine
Identification of therapeutic targets for nephrogenic diabetes insipidus
Zirconia ceramics: promising restorative material offers strength and aesthetics
Therapeutic targets in chronic active EBV infection
Highlights of Recent Notable Publications
TMDU's International Collaboration and Education
TMDU Research Activities 2018
TMDU Research Activities 2018
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Research at TMDU
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Features of TMDU Research
Large datasets of entire genomes will help identify disease subtypes and optimize treatments
Natural antibodies identified as potential anti-tumor agents
Know your enemy to know your strategy: Identification of genomic signatures and biochemical pathways in precision medicine
Nuclear receptors as drug targets
Uncovering the molecular mechanisms of blood and lymphatic vessel formation
Budding Researchers
Budding Researchers
Learning from the deceased to help the living
Targeting intercellular communication between bone cells
Validation of prospectively isolated mesenchymal stem cells
Therapeutic applications of supramolecular polymers
Highlights of Recent Notable Publications
TMDU's International Collaboration and Education
TMDU Research Activities 2017
TMDU Research Activities 2017
Message from the President
Research at TMDU
History and Location of TMDU
Cutting-Edge Research at TMDU
Features of TMDU Research
Features of TMDU Research
Basophil protease and allergic inflammation: Uncovering new links
New imaging technique for faster and more accurate detection of cavities
Synovial stem cells: Hope for cartilage and meniscus regeneration in osteoarthritis
Three-dimensional MRI offers new insights into globe shape evaluation in ocular diseases
Ultra-early Alzheimer’s disease pathway offers preclinical therapy potential
Body cavity sensors offer monitoring solutions in daily medicine
Alternative autophagy pathways conserved from yeast to mammals
High pressure tissue decellularization offers promise for tissue engineering applications
Budding Researchers
Budding Researchers
Transistor-based sensing system finds ion leakage in cells injured by nanomaterials
Prevention of knee osteoarthritis: From reducing injury to restoring function
Study of neurodegenerative diseases and cell death in vivo finds new signaling pathway
Childcare leave and supportive colleagues make high-level research possible for mothers
Highlights of Recent Notable Publications
TMDU's International Collaboration and Education
TMDU Research Activities 2016
TMDU Research Activities 2016
Message from the President
Research at TMDU
Cutting-Edge Research at TMDU
Cutting-Edge Research at TMDU
Novel oligonucleotide based on DNA/RNA heteroduplex structures:
Opening a new horizon for human gene therapy
Innovative cloning-free CRISPR/Cas9 system:
Efficiently creating targeted model mice
Features of TMDU Research
Features of TMDU Research
Regenerative Medicine for Inflammatory Bowel Disease
Genomics in cancer research leads to improved prognoses and new therapies
Bone biology ～Beyond the boundaries～
Robotics in clinical medicine:
A robot that performs endoscopic surgery
Innovative Researchers
Innovative Researchers
Stem cell aging study for tissue regeneration
Big Data and Statistical Genetics
Highlights of Recent Notable Publications
Seeds of International Collaborations at TMDU
TMDU's International Collaboration and Education
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