業績研究室の業績についてご紹介いたします。

業績

2019～2025.10 業績

2025

  • Oba S, Hosoya T, Iwai H, Yasuda S. Long COVID: mechanisms of disease, multisystem sequelae, and prospects for treatment. Immunol Med. 2025 Oct 21:1-24. doi:  10.1080/25785826.2025.2570902
  • Oba S, Hosoya T, Yokoyama K, Tomioka H, Harada H, Yasuda S. Successfully treated mandibular osteomyelitis by TNF inhibitor in SAPHO syndrome. Arthritis Rheumatol. 2025 Sep 14. doi:  10.1002/art.43375
  • Ohmura K, Shimizu H, Tanaka Y, Hiromura K, Hayashi H, Kamada K, Minowa K, Kawahito Y, Iwashita A, Kaname S, Yasuda S, Hiramoto K, Maruyama S, Yajima N, Iwata Y, Matsumoto I, Gono T, Sato H, Kubo S, Nakayamada S, Ikeuchi H, Yuzawa Y, Kono M, Tamura N, Seno T, Kida T, Sakashita A, Onishi A, Morinobu A, Kawakami T, Hosoya T, Yamaguchi T, Kaneko Y, Hanaoka H, Kato S, Maeda K, Nakagawa S, Kondo Y, Kuwana M, Ishii T, Sumitomo S, Miyakoshi C, Atsumi T. Impact of glucocorticoid tapering speed on renal outcomes in proliferative lupus nephritis: a multicentre retrospective study. Rheumatology (Oxford). 2025 Sep 1;64(9):5014-5022. doi:  10.1093/rheumatology/keaf243
  • Itakura T, Sasaki H, Hosoya T, Umezawa N, Saito T, Iwai H, Hasegawa H, Sato H, Hirakawa A, Imai K, Morio T, Kimura N, Yasuda S. The role of TRECs/KRECs as immune indicators that reflect immunophenotypes and predict the risk of infection in systemic autoimmune diseases. Immunol Med. 2025 Sep;48(3):233-244. doi:  10.1080/25785826.2025.2460275
  • Fujiwara M, Oda A, Ohtake R, Namiki T, Mimori E, Yasuda S, Okiyama N. Hydroxychloroquine-Induced Generalized Pustular Psoriasis Successfully Treated With Secukinumab: A Case Report. J Dermatol. 2025 Aug 29. doi:  10.1111/1346-8138.17936
  • Kaneko S, Hatano M, Shimbo A, Miyaoka F, Irabu H, Akutsu Y, Hayashi Y, Mizuta M, Nakagishi Y, Akamine K, Iwata N, Furuno K, Tanaka T, Ueno K, Fujita S, Yokoyama K, Minato T, Izawa K, Yasumi T, Matsubayashi T, Hosoya T, Nishikawa H, Fujimura J, Asano R, Sugita Y, Watanabe K, Kobayashi A, Endo T, Eguchi K, Nishikomori R, Yasuoka R, Asano T, Kanno M, Hamada K, Fujita Y, Hayashi D, Watanabe S, Shiba T, Yasuda S, Mori M, Kanegane H, Takagi M, Shimizu M. Serum cytokine profiling differentiates underlying diseases in cytokine storm syndrome. Arthritis Rheumatol. 2025 Aug 8. doi:  10.1002/art.43349
  • Yuya Ando, Suguru Mabuchi, Norikazu Mataki, Satoshi Nakayama, Arata Honda, Mari Kamiya, Shinsuke Yasuda, Hiroaki Takeo, Shigeaki Aono, Masayoshi Hashimoto, Kenichi Harada, Naoya Murashima. Anti-centromere antibody positivity with coexisting idiopathic portal hypertension and primary biliary cholangitis progressing to limited cutaneous systemic sclerosis: a case report. Journal of Medical Case Reports. 2025.08; DOI:  10.1186/s13256-025-05426-5
  • Yoji Komiya, Takahiko Sugihara, Tatsuro Ishizaki, Naoki Kimura, Mari Kamiya, Fumio Hirano, Takumi Matsumoto, Hirokazu Sasaki, Tadashi Hosoya, Shigeto Tohma, Shinsuke Yasuda, Toshihiro Matsui. The impact of aging and glucocorticoid use on physical function of older rheumatoid arthritis in remission: analysis of a National Database of Rheumatic Disease in Japan. Clin Rheumatol. 2025.07; DOI:  10.1007/s10067-025-07599-2
  • Motokawa Y, Sugihara J, Tateishi T, Hosoya T, Yasuda S, Miyazaki Y, Takahashi H, Shiwaku H. Long COVID is associated with female sex; Anti-NCAM1 autoantibodies are absent in patients with long COVID. IBRO Neurosci Rep. 2025 Jul 9;19:252-256. doi:  10.1016/j.ibneur.2025.07.002
  • Kondo S, Umezawa N, Tagawa Y, Yasuda S. Successful treatment with tocilizumab in a case of familial Mediterranean fever with Takayasu arteritis. Mod Rheumatol Case Rep. 2025 Jul 25;9(2):rxaf027. doi:  10.1093/mrcr/rxaf027
  • Kurita T, Yamamoto A, Hosoya T, Tsuchida M, Yasuda S, Gu Y. Lack of knowledge, not vaccine hesitancy, is the main cause of low human papilloma virus vaccination rate among systemic lupus erythematosus patients in Japan after suspension of proactive recommendation: Analysis of a patients' survey. J Obstet Gynaecol Res. 2025 Jun;51(6):e16330. doi:  10.1111/jog.16330
  • Kurita T, Okamoto K, Sekiya N, Hanazawa R, Yamamoto A, Hosoya T, Hirakawa A, Yasuda S, Gu Y. Proposed Diagnostic Criteria for Invasive Pulmonary Aspergillosis in Patients with Autoimmune Inflammatory Rheumatic Diseases: A Proof-of-Concept Study. J Fungi (Basel). 2025 Jun 7;11(6):437. doi:  10.3390/jof11060437
  • Kawata D, Hasegawa H, Kimura N, Tagawa Y, Sasaki H, Yasuda S. Immune Checkpoint Inhibitor-Induced Myositis, Myocarditis, Myasthenia Gravis, and Autonomic Neuropathy Successfully Treated With Rituximab. Muscle Nerve. 2025 Mar;71(3):489-491. doi:  10.1002/mus.28339
  • Nomura M, Sugihara T, Baba H, Hosoya T, Kamiya M, Ishizaki T, Matsumoto T, Kubo K, Hirano F, Kojima M, Miyasaka N, Yasuda S, Harigai M. Long-term outcome of a treat-to-target strategy in late-onset rheumatoid arthritis with chronic lung disease: 5-year results of a prospective observational study. Arthritis Res Ther. 2025.02; 27(1); 22. DOI:  10.1186/s13075-025-03491-1
  • Watase M, Masaki K, Chubachi S, Namkoong H, Tanaka H, Lee H, Fukushima T, Otake S, Nakagawara K, Kusumoto T, Asakura T, Kamata H, Ishii M, Hasegawa N, Oyamada Y, Harada N, Ueda T, Ueda S, Ishiguro T, Arimura K, Saito F, Yoshiyama T, Nakano Y, Mutoh Y, Suzuki Y, Edahiro R, Sano H, Sato Y, Okada Y, Koike R, Kitagawa Y, Tokunaga K, Kimura A, Imoto S, Miyano S, Ogawa S, Kanai T, Fukunaga K, Japan COVID-19 Task Force. Corrigendum to ’Impact of accumulative smoking exposure and chronic obstructive pulmonary disease on COVID-19 outcomes: report based on findings from the Japan COVID-19 task force’ [ IJID 128 (2023) 121-127]. International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases. 2025.02; 151; 107322. DOI:  10.1016/j.ijid.2024.107322
  • Shimada T, Maetani T, Chubachi S, Tanabe N, Asakura T, Namkoong H, Tanaka H, Azekawa S, Otake S, Nakagawara K, Fukushima T, Watase M, Shiraishi Y, Terai H, Sasaki M, Ueda S, Kato Y, Harada N, Suzuki S, Yoshida S, Tateno H, Shimizu K, Sato S, Yamada Y, Jinzaki M, Hirai T, Okada Y, Koike R, Ishii M, Kimura A, Imoto S, Miyano S, Ogawa S, Kanai T, Fukunaga K. Erector Spinae Muscle to Epicardial Visceral Fat Ratio on Chest CT Predicts the Severity of Coronavirus Disease 2019. Journal of cachexia, sarcopenia and muscle. 2025.02; 16(1); e13721. DOI:  10.1002/jcsm.13721
  • Tomohiro Yata, Go Sato, Kotaro Ogawa, Tatsuhiko Naito, Kyuto Sonehara, Ryunosuke Saiki, Ryuya Edahiro, Shinichi Namba, Mitsuru Watanabe, Yuya Shirai, Kenichi Yamamoto, Ho NamKoong, Tomoko Nakanishi, Yuji Yamamoto, Akiko Hosokawa, Mamoru Yamamoto, Eri Oguro-Igashira, Takuro Nii, Yuichi Maeda, Kimiko Nakajima, Rika Nishikawa, Hiroaki Tanaka, Shingo Nakayamada, Koichi Matsuda, Chikako Nishigori, Shigetoshi Sano, Makoto Kinoshita, Ryuji Koike, Akinori Kimura, Seiya Imoto, Satoru Miyano, Koichi Fukunaga, Masahito Mihara, Yuko Shimizu, Izumi Kawachi, Katsuichi Miyamoto, Yoshiya Tanaka, Atsushi Kumanogoh, Masaaki Niino, Yuji Nakatsuji, Seishi Ogawa, Takuya Matsushita, Jun-Ichi Kira, Hideki Mochizuki, Noriko Isobe, Tatsusada Okuno, Yukinori Okada. Contribution of germline and somatic mutations to risk of neuromyelitis optica spectrum disorder. Cell Genom. 2025.02; 100776. DOI:  10.1016/j.xgen.2025.100776
  • Kyuto Sonehara, Yoshifumi Uwamino, Ryunosuke Saiki, Masaru Takeshita, Shinichi Namba, Shunsuke Uno, Tomoko Nakanishi, Tomoyasu Nishimura, Tatsuhiko Naito, Go Sato, Masahiro Kanai, Aoxing Liu, Bio-Environmental Response Sho Uchida, Toshinobu Kurafuji, Akiko Tanabe, Tomoko Arai, Akemi Ohno, Ayako Shibata, Shiho Tanaka, Masatoshi Wakui, Shoko Kashimura, Chiharu Tomi, Akemi Hara, Shiori Yoshikawa, Keiko Gotanda, Kana Misawa, Hiromu Tanaka, Shuhei Azekawa, Qingbo S Wang, Ryuya Edahiro, Yuya Shirai, Kenichi Yamamoto, Genta Nagao, Takuo Suzuki, Masato Kiyoshi, Akiko Ishii-Watabe, Shinichi Higashiue, Shuzo Kobayashi, Hiroki Yamaguchi, Yasushi Okazaki, Naoyuki Matsumoto, Akihide Masumoto, Hidenobu Koga, Akinori Kanai, Yoshiya Oda, Yutaka Suzuki, Koichi Matsuda, Yuko Kitagawa, Ryuji Koike, Akinori Kimura, Atsushi Kumanogoh, Akihiko Yoshimura, Seiya Imoto, Satoru Miyano, Takanori Kanai, Koichi Fukunaga, Naoki Hasegawa, Mitsuru Murata, Hiromichi Matsushita, Seishi Ogawa, Yukinori Okada, Ho Namkoong. Germline variants and mosaic chromosomal alterations affect COVID-19 vaccine immunogenicity. Cell Genom. 2025.02; 100783. DOI:  10.1016/j.xgen.2025.100783
  • Sasa N, Kojima S, Koide R, Hasegawa T, Namkoong H, Hirota T, Watanabe R, Nakamura Y, Oguro-Igashira E, Ogawa K, Yata T, Sonehara K, Yamamoto K, Kishikawa T, Sakaue S, Edahiro R, Shirai Y, Maeda Y, Nii T, Chubachi S, Tanaka H, Yabukami H, Suzuki A, Nakajima K, Arase N, Okamoto T, Nishikawa R, Namba S, Naito T, Miyagawa I, Tanaka H, Ueno M, Ishitsuka Y, Furuta J, Kunimoto K, Kajihara I, Fukushima S, Miyachi H, Matsue H, Kamata M, Momose M, Bito T, Nagai H, Ikeda T, Horikawa T, Adachi A, Matsubara T, Ikumi K, Nishida E, Nakagawa I, Yagita-Sakamaki M, Yoshimura M, Ohshima S, Kinoshita M, Ito S, Arai T, Hirose M, Tanino Y, Nikaido T, Ichiwata T, Ohkouchi S, Hirano T, Takada T, Tazawa R, Morimoto K, Takaki M, Konno S, Suzuki M, Tomii K, Nakagawa A, Handa T, Tanizawa K, Ishii H, Ishida M, Kato T, Takeda N, Yokomura K, Matsui T, Uchida A, Inoue H, Imaizumi K, Goto Y, Kida H, Fujisawa T, Suda T, Yamada T, Satake Y, Ibata H, Saigusa M, Shirai T, Hizawa N, Nakata K, Japan COVID-19 Task Force, Imafuku S, Tada Y, Asano Y, Sato S, Nishigori C, Jinnin M, Ihn H, Asahina A, Saeki H, Kawamura T, Shimada S, Katayama I, Poisner HM, Mack TM, Bick AG, Higasa K, Okuno T, Mochizuki H, Ishii M, Koike R, Kimura A, Noguchi E, Sano S, Inohara H, Fujimoto M, Inoue Y, Yamaguchi E, Ogawa S, Kanai T, Morita A, Matsuda F, Tamari M, Kumanogoh A, Tanaka Y, Ohmura K, Fukunaga K, Imoto S, Miyano S, Parrish NF, Okada Y. Blood DNA virome associates with autoimmune diseases and COVID-19. Nature genetics. 2025.01; 57(1); 65-79. DOI:  10.1038/s41588-024-02022-z
  • Watase M, Shiraishi Y, Chubachi S, Tanabe N, Maetani T, Asakura T, Namkoong H, Tanaka H, Shimada T, Azekawa S, Otake S, Fukushima T, Nakagawara K, Masaki K, Terai H, Mochimaru T, Sasaki M, Ueda S, Kato Y, Harada N, Suzuki S, Yoshida S, Tateno H, Yamada Y, Jinzaki M, Okada Y, Koike R, Ishii M, Kimura A, Imoto S, Miyano S, Ogawa S, Kanai T, Fukunaga K. Coronary Artery Calcification on Chest Computed Tomography as a Predictor of Cardiovascular Adverse Events in Patients With COVID-19 - A Multicenter Retrospective Study in Japan. Circulation journal : official journal of the Japanese Circulation Society. 2025.01; 89(3); 373-381. DOI:  10.1253/circj.CJ-24-0496
  • Izuka S, Umezawa N, Komai T, Sugimori Y, Kimura N, Mizoguchi F, Fujieda Y, Ninagawa K, Iwasaki T, Suzuki K, Takeuchi T, Ohmura K, Mimori T, Atsumi T, Kawakami E, Suzuki A, Kochi Y, Yamamoto K, Yasuda S, Okamura T, Ota M, Fujio K. Muscle Tissue Transcriptome of Idiopathic Inflammatory Myopathy Reflects the Muscle Damage Process by Monocytes and Presence of Skin Lesions. Arthritis Rheumatol. 2025 Jan;77(1):99-106. doi:  10.1002/art.42972
  • Sugihara J, Iwamura C, Tateishi T, Hosoya T, Shimada S, Hirahara K, Yasuda S, Miyazaki Y. Prolonged high Myl9 levels are associated with the pathogenesis and respiratory symptom of post-acute COVID-19 syndrome: A 6-month follow-up study. Clinics (Sao Paulo). 2025 Jan 28;80:100584. doi:  10.1016/j.clinsp.2025.100584

2024

  • Hiroshi Nakase, Kohei Wagatsuma, Taku Kobayashi, Takayuki Matsumoto, Motohiro Esaki, Kenji Watanabe, Reiko Kunisaki, Teruyuki Takeda, Katsuhiro Arai, Takashi Ibuka, Dai Ishikawa, Yuichi Matsuno, Hirotake Sakuraba, Nobuhiro Ueno, Kaoru Yokoyama, Masayuki Saruta, Ryota Hokari, Junji Yokoyama, Shu Tamano, Masanori Nojima, Tadakazu Hisamatsu, Shusaku Yoshikawa, Sohachi Nanjo, Akira Andoh, Takeshi Kimura, Makoto Ooi, Ryosuke Kiyomori, Nobuo Aoyama, Fumihito Hirai, Atsushi Yamaushi, Masanao Nakamura, Fumikazu Koyama, Shuhei Hosomi, Kazuki Kakimoto, Satoshi Motoya, Ryosuke Sakemi, Hideo Suzuki, Tadashi Hosoya, Ken Takeuchi, Manabu Shiraki, Hideyuki Koide, Ichiro Takeuchi, Yosuke Furui, Kento Yoshida, Ayaka Minemura, Asami Matsumoto, Kentaro Oka. Involvement of Mediterranean fever gene mutations in colchicine-responsive enterocolitis: a retrospective cohort study. eBioMedicine. 2024 Dec;110:105454. DOI:  10.1016/j.ebiom.2024.105454
  • Takashi Ishikawa, Kenichi Nishimura, Nami Okamoto, Keiji Akamine, Natsumi Inoue, Hitoshi Irabu, Kentaro Kato, Hiroshi Keino, Masayo Kojima, Hiroshi Kubo, Kazuichi Maruyama, Mao Mizuta, Kosuke Shabana, Masaki Shimizu, Yuko Sugita, Yukiko Takakuwa, Satoshi Takanashi, Hiroshi Takase, Hiroaki Umebayashi, Natsuka Umezawa, Shingo Yamanishi, Kazuko Yamazaki, Masato Yashiro, Takahiro Yasumi, Masaaki Mori. Efficacy and safety of tumor necrosis factor inhibitors for systemic juvenile idiopathic arthritis: a systematic review. Mod Rheumatol. 2024 Dec;35(1):174-184. DOI:  10.1093/mr/roae050
  • Tanaka Hiromu, Toya Erika, Chubachi Shotaro, Namkoong Ho, Asakura Takanori, Azekawa Shuhei, Otake Shiro, Nakagawara Kensuke, Fukushima Takahiro, Watase Mayuko, Sakurai Kaori, Masaki Katsunori, Kamata Hirofumi, Ishii Makoto, Hasegawa Naoki, Okada Yukinori, Koike Ryuji, Kitagawa Yuko, Kimura Akinori, Imoto Seiya, Miyano Satoru, Ogawa Seishi, Kanai Takanori, Fukunaga Koichi. Combined use of serum ferritin and KL-6 levels as biomarkers for predicting COVID-19 severity. Respiratory Investigation. 2024 Nov;62(6):1132-1136. DOI:  10.1016/j.resinv.2024.07.006
  • Wang QS, Hasegawa T, Namkoong H, Saiki R, Edahiro R, Sonehara K, Tanaka H, Azekawa S, Chubachi S, Takahashi Y, Sakaue S, Namba S, Yamamoto K, Shiraishi Y, Chiba K, Tanaka H, Makishima H, Nannya Y, Zhang Z, Tsujikawa R, Koike R, Takano T, Ishii M, Kimura A, Inoue F, Kanai T, Fukunaga K, Ogawa S, Imoto S, Miyano S, Okada Y, Japan COVID-19 Task Force. Statistically and functionally fine-mapped blood eQTLs and pQTLs from 1,405 humans reveal distinct regulation patterns and disease relevance. Nature Genetics. 2024 Sep;56(10):2054-2067. DOI:  10.1038/s41588-024-01896-3
  • Miyamae T, Manabe Y, Sugihara T, Umezawa N, Yoshifuji H, Tamura N, Abe Y, Furuta S, Nagafuchi H, Ishizaki J, Nakano N, Atsumi T, Karino K, Amano K, Kurasawa T, Ito S, Yoshimi R, Ogawa N, Banno S, Naniwa T, Ito S, Hara A, Hirahara S, Uchida HA, Onishi Y, Murakawa Y, Komagata Y, Nakaoka Y, Harigai M. Pregnancy and childbirth in Takayasu arteritis in Japan: A nationwide retrospective study. Modern Rheumatology. 2024 Aug;35(2):339-344. DOI:  10.1093/mr/roaa273
  • Komiya Y, Kamiya M, Oba S, Kawata D, Iwai H, Shintaku H, Suzuki Y, Miyamoto S, Tobiume M, Kanno T, Ainai A, Suzuki T, Hasegawa H, Hosoya T, Yasuda S. Necroptosis in alveolar epithelial cells drives lung inflammation and injury caused by SARS-CoV-2 infection. Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease. 2024 Aug;1870(8):167472. DOI:  10.1016/j.bbadis.2024.167472
  • Izuka S, Umezawa N, Komai T, Sugimori Y, Kimura N, Mizoguchi F, Fujieda Y, Ninagawa K, Iwasaki T, Suzuki K, Takeuchi T, Ohmura K, Mimori T, Atsumi T, Kawakami E, Suzuki A, Kochi Y, Yamamoto K, Yasuda S, Okamura T, Ota M, Fujio K. The muscle tissue transcriptome of idiopathic inflammatory myopathy reflects the muscle damage process by monocytes and presence of skin lesions. Arthritis & Rheumatology (Hoboken, N.J.). 2024 Aug;77(1):99-106. DOI:  10.1002/art.42023
  • Takahashi Sunao, Sanjo Nobuo, Koike Ryuji, Yokota Takanori. Eculizumab administration for myasthenia gravis also stabilizes thrombogenicity of catastrophic antiphospholipid syndrome. Clinical and Experimental Neuroimmunology. 2024 Aug;15(3):143-145. DOI:  10.1111/cen3.12992
  • Azekawa S, Maetani T, Chubachi S, Asakura T, Tanabe N, Shiraishi Y, Namkoong H, Tanaka H, Shimada T, Fukushima T, Otake S, Nakagawara K, Watase M, Terai H, Sasaki M, Ueda S, Kato Y, Harada N, Suzuki S, Yoshida S, Tateno H, Yamada Y, Jinzaki M, Hirai T, Okada Y, Koike R, Ishii M, Kimura A, Imoto S, Miyano S, Ogawa S, Kanai T, Fukunaga K. CT-derived vertebral bone mineral density is a useful biomarker to predict COVID-19 outcome. Bone. 2024 Jul;184:117095. DOI:  10.1016/j.bone.2023.117095
  • Takayuki Miyamoto, Kazushi Izawa, Sho Masui, Atsue Yamazaki, Yuichi Yamasaki, Tadashi Matsubayashi, Mayuka Shiraki, Hidenori Ohnishi, Junko Yasumura, Tomohiro Kawabe, Takako Miyamae, Tomoyo Matsubara, Naoya Arakawa, Takashi Ishige, Takumi Takizawa, Asami Shimbo, Masaki Shimizu, Naoki Kimura, Yuichi Maeda, Yuta Maruyama, Tomonari Shigemura, Junichi Furuta, Satoshi Sato, Hiroshi Tanaka, Miharu Izumikawa, Masahiro Yamamura, Toshio Hasegawa, Hiroshi Kaneko, Yasuo Nakagishi, Naoko Nakano, Yasunori Iida, Tamaki Nakamura, Hiroyuki Wakiguchi, Takayuki Hoshina, Toshinao Kawai, Kosaku Murakami, Shuji Akizuki, Akio Morinobu, Koichiro Ohmura, Katsuhide Eguchi, Motoshi Sonoda, Masataka Ishimura, Kenji Furuno, Momoko Kashiwado, Masaaki Mori, Kimito Kawahata, Koremasa Hayama, Kumiko Shimoyama, Natsuko Sasaki, Taisuke Ito, Hiroaki Umebayashi, Tae Omori, Seiko Nakamichi, Tomotsune Dohmoto, Yasuyuki Hasegawa, Hisashi Kawashima, Shojiro Watanabe, Yuichiro Taguchi, Haruna Nakaseko, Naomi Iwata, Hiroki Kohno, Taiki Ando, Yasuhiko Ito, Yuko Kataoka, Takako Saeki, Utako Kaneko, Ayako Murase, Seira Hattori, Tomo Nozawa, Kenichi Nishimura, Reiji Nakano, Misa Watanabe, Masato Yashiro, Tomonori Nakamura, Toshihiko Komai, Kentaro Kato, Yoshitaka Honda, Eitaro Hiejima, Atsushi Yonezawa, Kazuhisa Bessho, Satoshi Okada, Osamu Ohara, Junko Takita, Takahiro Yasumi, Ryuta Nishikomori. Clinical Characteristics of Cryopyrin-Associated Periodic Syndrome and Long-Term Real-World Efficacy and Tolerability of Canakinumab in Japan: Results of a Nationwide Survey. Arthritis Rheumatol. 2024 Jun;76(6):949-962. DOI:  10.1016/j.bone.2023.117095
  • Kawata D, Iwai H, Oba S, Komiya Y, Koike R, Miyamoto S, Kanno T, Ainai A, Suzuki T, Hosoya T, Yasuda S. Diverse pro-inflammatory ability of mutated spike protein derived from variant strains of SARS-CoV-2. Cytokine. 2024 Jun;178:156592. DOI:  10.1016/j.cyto.2023.156592
  • Tagawa Y, Saito T, Iwai H, Sato M, Noda S, Yamamoto A, Ota M, Endo K, Koga H, Takahara Y, Sugimoto K, Sekiya I, Fujio K, Kawakami E, Mizoguchi F, Yasuda S.ARID5B is a negative modulator of IL-6 production in rheumatoid arthritis synovial fibroblasts. Immunological Medicine. 2024 May;47(3):1-10. DOI:  10.1080/25785826.2024.1183452
  • Tanaka H, Chubachi S, Asakura T, Namkoong H, Azekawa S, Otake S, Nakagawara K, Fukushima T, Lee H, Watase M, Sakurai K, Kusumoto T, Masaki K, Kamata H, Ishii M, Hasegawa N, Okada Y, Koike R, Kitagawa Y, Kimura A, Imoto S, Miyano S, Ogawa S, Kanai T, Fukunaga K. Prognostic significance of chronic kidney disease and impaired renal function in Japanese patients with COVID-19. BMC Infectious Diseases. 2024 May;24(1):527. DOI:  10.1186/s12879-024-05177-z
  • Otake S, Shiraishi Y, Chubachi S, Tanabe N, Maetani T, Asakura T, Namkoong H, Shimada T, Azekawa S, Nakagawara K, Tanaka H, Fukushima T, Watase M, Terai H, Sasaki M, Ueda S, Kato Y, Harada N, Suzuki S, Yoshida S, Tateno H, Yamada Y, Jinzaki M, Hirai T, Okada Y, Koike R, Ishii M, Hasegawa N, Kimura A, Imoto S, Miyano S, Ogawa S, Kanai T, Fukunaga K. Lung volume measurement using chest CT in COVID-19 patients: a cohort study in Japan. BMJ Open Respiratory Research. 2024 Apr;11(1). DOI:  10.1136/bmjresp-2023-001891
  • Zento Yamada, Sei Muraoka, Mai Kawazoe, Wataru Hirose, Hajime Kono, Shinsuke Yasuda, Takahiko Sugihara, Toshihiro Nanki. Long-term effects of abatacept on atherosclerosis and arthritis in older vs. younger patients with rheumatoid arthritis: 3-year results of a prospective, multicenter, observational study. Arthritis Research & Therapy. 2024 Apr 17;26(1):87. DOI:  10.1186/s13075-024-02462-z
  • Hiroyuki Baba, Tadashi Hosoya, Ryosuke Ishida, Kenpei Tai, Saki Hatsuzawa, Yuma Kondo, Hiroyuki Kusuhara, Hiroyuki Kagechika, Shinsuke Yasuda. Anti-Inflammatory Effects of a Novel Nuclear Factor–κB Inhibitory Derivative Derived from Pyrazolo[3,4-d]Pyrimidine in Three Inflammation Models. Journal of Pharmacology and Experimental Therapeutics. 2024 Mar;388(3):788-797. DOI:  10.1124/jpet.123.001432
  • Yuta Matsubara, Hiroki Kiyohara, Yohei Mikami, Kosaku Nanki, Ho Namkoong, Shotaro Chubachi, Hiromu Tanaka, Shuhei Azekawa, Shinya Sugimoto, Yusuke Yoshimatsu, Tomohisa Sujino, Kaoru Takabayashi, Naoki Hosoe, Toshiro Sato, Makoto Ishii, Naoki Hasegawa, Yukinori Okada, Ryuji Koike, Yuko Kitagawa, Akinori Kimura, Seiya Imoto, Satoru Miyano, Seishi Ogawa, Koichi Fukunaga, Takanori Kanai, Japan COVID-19 Task Force. Gastrointestinal symptoms in COVID-19 and disease severity: a Japanese registry-based retrospective cohort study. Journal of Gastroenterology. 2024 Mar;59(3):195-208. DOI:  10.1007/s00535-023-02005-5
  • Nakagawara K, Shiraishi Y, Chubachi S, Tanabe N, Maetani T, Asakura T, Namkoong H, Tanaka H, Shimada T, Azekawa S, Otake S, Fukushima T, Watase M, Shiraishi Y, Terai H, Sasaki M, Ueda S, Kato Y, Harada N, Suzuki S, Yoshida S, Tateno H, Yamada Y, Jinzaki M, Hirai T, Okada Y, Koike R, Ishii M, Kimura A, Imoto S, Miyano S, Ogawa S, Kanai T, Fukunaga K. Integrated assessment of computed tomography density in pectoralis and erector spinae muscles as a prognostic biomarker for coronavirus disease 2019. Clinical Nutrition (Edinburgh, Scotland). 2024 Mar;43(3):815-824. DOI:  10.1016/j.clnu.2023.12.022
  • Takumi Matsumoto, Takahiko Sugihara, Tadashi Hosoya, Tatsuro Ishizaki, Kanae Kubo, Mari Kamiya, Hiroyuki Baba, Marina Tsuchida, Fumio Hirano, Masayo Kojima, Nobuyuki Miyasaka, Masayoshi Harigai. Effectiveness and safety of treat-to-target strategy for methotrexate-naive rheumatoid arthritis patients 75 years of age. Rheumatology Advances in Practice. 2024 Feb;8(1):rkae019. DOI:  10.1093/rap/rkae019
  • Komiya Yoji, Sugihara Takahiko, Hirano Fumio, Matsumoto Takumi, Kamiya Mari, Sasaki Hirokazu, Hosoya Tadashi, Kimura Naoki, Ishizaki Tatsuro, Mori Masaaki, Tohma Shigeto, Yasuda Shinsuke, Matsui Toshihiro. Factors associated with impaired physical function in elderly rheumatoid arthritis patients who had achieved low disease activity. Modern Rheumatology. 2024 Jan;34(1):60-67. DOI:  10.1080/14397595.2023.2293402
  • Hiroyuki Baba, Naoki Kimura, Hirokazu Kanegane, Fuyuki Miya, Kenjiro Kosaki, Tomohiro Morio, Ryuji Koike. GATA2 deficiency of a novel missense variant with multiorgan inflammation. Rheumatology (Oxford). 2024 Jan. DOI:  10.1093/rheumatology/keac087
  • Fukushima T, Maetani T, Chubachi S, Tanabe N, Asakura T, Namkoong H, Tanaka H, Shimada T, Azekawa S, Otake S, Nakagawara K, Watase M, Shiraishi Y, Terai H, Sasaki M, Ueda S, Kato Y, Harada N, Suzuki S, Yoshida S, Tateno H, Yamada Y, Jinzaki M, Hirai T, Okada Y, Koike R, Ishii M, Kimura A, Imoto S, Miyano S, Ogawa S, Kanai T, Fukunaga K. Epicardial adipose tissue measured from analysis of adipose tissue area using chest CT imaging is the best potential predictor of COVID-19 severity. Metabolism: Clinical and Experimental. 2024 Jan;150:155715. DOI:  10.1016/j.metabol.2023.155715
  • T Tsubata, N Umezawa, T Yasumi, H Kanegane, S Yasuda. Impaired development of B cells with PRF1 variants in an adult. Scandinavian Journal of Rheumatology. 2024 Jan;53(1):74-76. DOI:  10.1080/03009742.2023.2272041

2023

  • Sasaki H, Umezawa N, Itakura T, Iwai H, Yasuda S. Pathogenicity of functionally activated PD-1(+)CD8(+) cells and counterattacks by muscular PD-L1 through IFN γ in myositis. Journal of autoimmunity. 2023.11; 142; 103131. doi:  10.1016/j.jaut.2023.103131
  • Hanzawa S, Noda S, Hosoya T, Kawahara T, Nukui Y. Mass-like Lesions Causing Compression of Large Vessels in Granulomatosis with Polyangiitis. Internal medicine (Tokyo, Japan). 2023.08; 62(16); 2427-2431. doi:  10.2169/internalmedicine.0561-22
  • Mari Kamiya, Naoki Kimura, Natsuka Umezawa, Hisanori Hasegawa and Shinsuke Yasuda. Muscle fiber necroptosis in pathophysiology of idiopathic inflammatory myopathies and its potential as target of novel treatment strategy. Frontiers in Immunology. 2023.07; 14; 1191815. doi:  10.3389/fimmu.2023.1191815
  • Mitsui Y, Suzuki T, Kuniyoshi K, Inamo J, Yamaguchi K, Komuro M, Watanabe J, Edamoto M, Li S, Kouno T, Oba S, Hosoya T, Masuhiro K, Naito Y, Koyama S, Sakaguchi N, Standley DM, Shin JW, Akira S, Yasuda S, Miyazaki Y, Kochi Y, Kumanogoh A, Okamoto T, Satoh T. Expression of the readthrough transcript CiDRE in alveolar macrophages boosts SARS-CoV-2 susceptibility and promotes COVID-19 severity. Immunity. 2023.07; 56(8); 1939-1954.e12. doi:  10.1002/art.42415
  • Baba, H; Sugihara, T; Ishizaki, T; Nomura, M; Hosoya, T; Kamiya, M; Matsumoto, T; Kubo, K; Hirano, F; Miyasaka, N; Kojima, M; Yasuda, S; Harigai, M. LONG-TERM OUTCOMES OF METHOTREXATE IN ELDERLY-ONSET RA IMPLEMENTING THE TREAT-TO-TARGET STRATEGY. ANNALS OF THE RHEUMATIC DISEASES. 2023.06; 82; 1293-1294. doi:  10.1136/annrheumdis-2023-eular.5282
  • Tanaka Keisuke, Ichikawa Ayako, Umezawa Natsuka, Yamamoto Kouhei, Yoshifuji Kota, Okada Keigo, Nogami Ayako, Umezawa Yoshihiro, Nagao Toshikage, Sakashita Chizuko, Mori Takehiko, Tohda Shuji, Koike Ryuji, Yasuda Shinsuke, Yamamoto Masahide. Lymphoproliferative disorder risk after methotrexate treatment for rheumatoid arthritis. CANCER SCIENCE. 2023.06. doi:  10.1111/cas.15894
  • Natsuka Umezawa, Fumitaka Mizoguchi, Yasuhiro Maejima, Naoki Kimura, Hisanori Hasegawa, Tadashi Hosoya, Minoru Fujimoto, Hitoshi Kohsaka, Tetsuji Naka, Shinsuke Yasuda. Leucine-rich alpha-2 glycoprotein as a potential biomarker for large vessel vasculitides. Front Med (Lausanne). 2023.05; 10; 1153883. doi:  10.3389/fmed.2023.1153883
  • Hosoya T, Oba S, Komiya Y, Kawata D, Kamiya M, Iwai H, Miyamoto S, Kataoka M, Tobiume M, Kanno T, Ainai A, Sato H, Hirakawa A, Mitsui Y, Satoh T, Wakabayashi K, Yamada T, Otomo Y, Miyazaki Y, Hasegawa H, Suzuki T, Yasuda S. Apple-shaped obesity: A risky soil for cytokine-accelerated severity in COVID-19. Proceedings of the National Academy of Sciences of the United States of America. 2023.05; 120(22); e2300155120. doi:  10.1073/pnas.2300155120
  • Fujiwara S, Kawamoto A, Motobayashi M, Hibiya S, Takenaka K, Shimizu H, Saito E, Fujii T, Nagahori M, Kawata D, Umezawa N, Hosoya T, Yasuda S, Ohtsuka K, Okamoto R. Hemorrhagic gastric ulcer in a patient with Behcet’s disease successfully treated with infliximab. DEN open. 2023.04; 3(1); e196. doi:  10.1002/deo2.196
  • Itakura Takuji, Sasaki Hirokazu, Hosoya Tadashi, Yamaguchi Taiki, Mimori Erika, Saimon Yukino, Iwai Hideyuki, Umezawa Natsuka, Kawata Daisuke, Kimura Naoki, Kurata Morito, Shimizu Masaki, Yasuda Shinsuke. A novel gain-of-function missense variant in PLCG2 associated with autoinflammation and hypergammaglobulinaemia. RHEUMATOLOGY. 2023.04; 62(11); e319-e321. doi:  10.1093/rheumatology/kead051

2022.Sep

  • Umezawa N, Sasaki H, Furusawa H, Kawata D, Hata C, Yasuda S. Development of vasculitis in a case with severe asthma treated with benralizumab and low-dose corticosteroid. Allergology international : official journal of the Japanese Society of Allergology. 2022.09;DOI: 10.1016/j.alit.2022.08.004
  • Lee H, Chubachi S, Namkoong H, Tanaka H, Otake S, Nakagawara K, Morita A, Fukushima T, Watase M, Kusumoto T, Masaki K, Kamata H, Ishii M, Hasegawa N, Harada N, Ueda T, Ueda S, Ishiguro T, Arimura K, Saito F, Yoshiyama T, Nakano Y, Mutoh Y, Suzuki Y, Murakami K, Okada Y, Koike R, Kitagawa Y, Kimura A, Imoto S, Miyano S, Ogawa S, Kanai T, Fukunaga K, Japan COVID-19 Task Force.. Effects of mild obesity on outcomes in Japanese patients with COVID-19: a nationwide consortium to investigate COVID-19 host genetics. Nutrition & diabetes. 2022.08; 12(1); 38 DOI: 10.1038/s41387-022-00217-z
  • Fukushima T, Chubachi S, Namkoong H, Otake S, Nakagawara K, Tanaka H, Lee H, Morita A, Watase M, Kusumoto T, Masaki K, Kamata H, Ishii M, Hasegawa N, Harada N, Ueda T, Ueda S, Ishiguro T, Arimura K, Saito F, Yoshiyama T, Nakano Y, Mutoh Y, Suzuki Y, Murakami K, Okada Y, Koike R, Kitagawa Y, Kimura A, Imoto S, Miyano S, Ogawa S, Kanai T, Fukunaga K, Japan COVID-19 Task Force.. U-shaped association between abnormal serum uric acid levels and COVID-19 severity: Reports from the Japan COVID-19 Task Force. International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases. 2022.07;DOI: 10.1016/j.ijid.2022.07.014
  • Mari Kamiya,Fumitaka Mizoguchi,Shinsuke Yasuda. Amelioration of inflammatory myopathies by glucagon-like peptide-1 receptor agonist via suppressing muscle fibre necroptosis Journal of Cachexia, Sarcopenia and Muscle. 2022.06; 13(4); 2118-2131 DOI: 10.1002/jcsm.13025
  • Tomoko Niwano, Tadashi Hosoya, Saori Kadowaki, Etsushi Toyofuku, Takuya Naruto, Masaki Shimizu, Hidenori Ohnishi, Ryuji Koike, Tomohiro Morio, Kohsuke Imai, Masayuki Yoshida, Shinsuke Yasuda. An adult case of suspected A20 haploinsufficiency mimicking polyarteritis nodosa. Rheumatology (Oxford). 2022.05; DOI: 10.1093/rheumatology/keac308
  • Yoshizuka R, Hasegawa H, Kamiya M, Umezawa N, Yasuda S. Refractory antiphospholipid antibody syndrome-induced thrombocytopaenia successfully treated with belimumab. Lupus. 2022.04; 31(5); 624-627 DOI: 10.1177/09612033221089138
  • Fumiaki Kondo, Takahiko Sugihara, Natsuka Umezawa, Hisanori Hasegawa, Tadashi Hosoya, Naoki Kimura, Masaaki Mori, Shinsuke Yasuda. Associated factors with poor treatment response to initial glucocorticoid therapy in patients with adult-onset Still’s disease. Arthritis Res Ther. 2022.04; 24(1); 92 DOI: 10.1186/s13075-022-02780-3
  • Nishijima H, Sugita M, Umezawa N, Kimura N, Sasaki H, Kawano H, Nishioka Y, Matsumoto M, Oya T, Tsuneyama K, Morimoto J, Matsumoto M. Development of organ-specific autoimmunity by dysregulated Aire expression. Immunology and cell biology. 2022.03; 100(5); 371-377 DOI: 10.1111/imcb.12546
  • Kimura Naoki, Kawahara Takuya, Uemura Yukari, Atsumi Tatsuya, Sumida Takayuki, Mimura Toshihide, Kawaguchi Yasushi, Amano Hirofumi, Iwasaki Yukiko, Kaneko Yuko, Matsui Toshihiro, Muro Yoshinao, Imura Yoshitaka, Kanda Takashi, Tanaka Yoshiya, Kawakami Atsushi, Jinnin Masatoshi, Ishii Tomonori, Hiromura Keiju, Miwa Yusuke, Nakajima Hiroshi, Kuwana Masataka, Nishioka Yasuhiko, Morinobu Akio, Kameda Hideto, Kohsaka Hitoshi. Branched chain amino acids in the treatment of polymyositis and dermatomyositis: a phase II/III, multi-centre, randomized controlled trial RHEUMATOLOGY. 2022.02; DOI: 10.1093/rheumatology/keac101
  • Tetsuya Saito, Nikunj M Shukla, Fumi Sato-Kaneko, Yukiya Sako, Tadashi Hosoya, Shiyin Yao, Fitzgerald S Lao, Karen Messer, Minya Pu, Michael Chan, Paul J Chu, Howard B Cottam, Tomoko Hayashi, Dennis A Carson, Maripat Corr. Small Molecule Calcium Channel Activator Potentiates Adjuvant Activity. ACS Chem Biol. 2022.01; 17(1); 217-229 DOI: 10.1021/acschembio.1c00883
  • Mari Kamiya, Fumitaka Mizoguchi, Kimito Kawahata, Dengli Wang, Masahiro Nishibori, Jessica Day, Cynthia Louis, Ian P Wicks, Hitoshi Kohsaka, Shinsuke Yasuda. Targeting necroptosis in muscle fibers ameliorates inflammatory myopathies Nature Communications. 2022.01; 13(1); 166 DOI: 10.1038/s41467-021-27875-4

2021

  • Yusuke Ota, Natsune Hongou, Yoko Nukui, Ryuji Koike, Shuji Tohda, Ryoichi Saito. Evaluation of polymerase chain reaction-based open reading frame typing method for the clonality investigation of Clostridioides difficile isolates. Anaerobe. 2021.12; 72; 102462 DOI: 10.1097/RHU.0000000000001717
  • Yamamoto A, Saito T, Hosoya T, Kawahata K, Asano Y, Sato S, Mizoguchi F, Yasuda S, Kohsaka H. Therapeutic effect of cyclin-dependent kinase 4/6 inhibitor on dermal fibrosis in murine models of systemic sclerosis. Arthritis & rheumatology (Hoboken, N.J.). 2021.12; DOI: 10.1002/art.42042
  • Sei Muraoka, Zento Yamada, Mai Kawazoe, Wataru Hirose, Hajime Kono, Shinsuke Yasuda, Yukiko Komano, Hiroshi Kawano, Toshihiko Hidaka, Shusaku Nakashima, Tsuyoshi Kasama, Tamio Teramoto, Toshihiro Nanki, . Abatacept is Efficacious in the Treatment of Older Patients with csDMARD-Refractory Rheumatoid Arthritis: A Prospective, Multicenter, Observational Study. Rheumatol Ther. 2021.12; 8(4); 1585-1601 DOI: 10.1007/s40744-021-00356-2
  • Tanaka Hiromu, Lee Ho, Morita Atsuho, Namkoong Ho, Chubachi Shotaro, Kabata Hiroki, Kamata Hirofumi, Ishii Makoto, Hasegawa Naoki, Harada Norihiro, Ueda Tetsuya, Ueda Soichiro, Ishiguro Takashi, Arimura Ken, Saito Fukuki, Yoshiyama Takashi, Nakano Yasushi, Mutoh Yoshikazu, Suzuki Yusuke, Murakami Koji, Okada Yukinori, Koike Ryuji, Kitagawa Yuko, Tokunaga Katsushi, Kimura Akinori, Imoto Seiya, Miyano Satoru, Ogawa Seishi, Kanai Takanori, Fukunaga Koichi. Clinical Characteristics of Patients with Coronavirus Disease (COVID-19): Preliminary Baseline Report of Japan COVID-19 Task Force, a Nationwide Consortium to Investigate Host Genetics of COVID-19 INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES. 2021.12; 113; 74-81 DOI: 10.1016/j.ijid.2021.09.070
  • Hosoya T, Oda G, Nakagawa T, Onishi I, Hosoya T, Ishiguro M, Ishikawa T, Uetake H. Plasma Levels of Decorin Increased in Patients during the Progression of Breast Cancer. Journal of clinical medicine. 2021.11; 10(23); DOI: 10.3390/jcm10235530
  • Sugihara T, Nakaoka Y, Uchida HA, Yoshifuji H, Maejima Y, Watanabe Y, Amiya E, Tanemoto K, Miyata T, Umezawa N, Manabe Y, Ishizaki J, Shirai T, Nagafuchi H, Hasegawa H, Miyamae T, Niiro H, Ito S, Ishii T, Isobe M, Harigai M. Establishing Clinical Remission Criteria and the Framework of a Treat-To-Target Algorithm for Takayasu arteritis: Results of a Delphi Exercise Carried out by an Expert Panel of the Japan Research Committee of the Ministry of Health, Labour, and Welfare for intractable vasculitis. Modern rheumatology. 2021.11; DOI: 10.1093/mr/roab081
  • Tadashi Hosoya, Tetsuya Saito, Hiroyuki Baba, Nao Tanaka, Seiji Noda, Youji Komiya, Yasuhiro Tagawa, Akio Yamamoto, Fumitaka Mizoguchi, Kimito Kawahata, Nobuyuki Miyasaka, Hitoshi Kohsaka, Shinsuke Yasuda. Chondroprotective effects of CDK4/6 inhibition via enhanced ubiquitin-dependent degradation of JUN in synovial fibroblasts. Rheumatology (Oxford). 2021.11; DOI: 10.1093/rheumatology/keab874
  • Takagi M., Ogawa C., Iehara T., Aoki-Nogami Y., Isibashi E., Imai M., Kimura T., Nagata M., Yasuhara M., Masutani M., Yoshimura K., Tomizawa D., Ogawa A., Yonemori K., Kihara T., Nobori K., Hasebe K., Mizutani S., Morio T., Hosoi H., Koike R.. First in Children Phase I Clinical Study of Oral Olaparib in Pediatric Patients with Refractory Solid Tumors PEDIATRIC BLOOD & CANCER. 2021.11; 68; S85-S86 DOI: 10.1186/s12887-019-1409-7
  • Saito T, Sako Y, Sato-Kaneko F, Hosoya T, Yao S, Lao FS, Shpigelman J, Messer K, Pu M, Shukla NM, Chan M, Chu PJ, Cottam HB, Hayashi T, Carson DA, Corr M. Small Molecule Potentiator of Adjuvant Activity Enhancing Survival to Influenza Viral Challenge. Frontiers in immunology. 2021.09; 12; 701445 DOI: 10.3389/fimmu.2021.701445
  • Tadashi Hosoya, Dunai Cordelia, Benedict D Michael, Chie Miyabe, Jun Nagai, Thomas T Murooka, Yoshishige Miyabe. Editorial: Targeting the Chemoattractant System in Inflammation. Front Pharmacol. 2021.08; 12; 744290 DOI: 10.3389/fphar.2021.744290
  • Ishiguro Nobuhisa, Ito Yoichi M., Iwasaki Sumio, Nagao Miki, Kawamura Hideki, Kanai Shinichiro, Nukui Yoko, Tokuda Koichi, Miyara Takayuki, Igari Hidetoshi, Yamada Koichi, Chikumi Hiroki, Sano Chiaki, Koike Ryuji, Yagi Tetsuya, Murakami Nobuo. Three-day regimen of oseltamivir for post-exposure prophylaxis of influenza in hospital wards: a study protocol for a prospective, multi-center, single-arm trial BMC INFECTIOUS DISEASES. 2021.08; 21(1); 887 DOI: 10.1186/s12879-021-06602-w
  • Tadashi Hosoya, Takahiko Sugihara, Nobuyuki Miyasaka, Shinsuke Yasuda. Novel treatment strategy of polymyalgia rheumatica targeting drug-free remission. Clin Exp Rheumatol. 2021.05; 39(3); 701-702 DOI: 10.55563/clinexprheumatol/ozxm7y
  • Yuichiro Fujieda, Tetsuya Horita, Naoki Nishimoto, Kazuhide Tanimura, Yoshiharu Amasaki, Hideki Kasahara, Shin Furukawa, Tsuyoshi Takeda, Shinji Fukaya, Kazuo Matsui, Akito Tsutsumi, Akira Furusaki, Akira Sagawa, Kou Katayama, Kaoru Takeuchi, Kazuaki Katsumata, Takashi Kurita, Peter Shane, Masaru Kato, Kenji Oku, Shinsuke Yasuda, Masahiko Takahata, Norimasa Iwasaki, Tatsuya Atsumi. Efficacy and safety of sodium RISedronate for glucocorticoid-induced OsTeoporosis with rheumaTOid arthritis (RISOTTO study): A multicentre, double-blind, randomized, placebo-controlled trial. Mod Rheumatol. 2021.05; 31(3); 593-599 DOI: 10.1080/14397595.2020.1812835
  • Mori M, Watabe S, Taguchi T, Hasegawa H, Ishige M, Tanuma N, Hirakawa A, Koike R, Kusuda S. Study protocol: a multicenter, uncontrolled, open-label study of palivizumab in neonates, infants, and preschool children at high risk of severe respiratory syncytial virus infection. BMC pediatrics. 2021.03; 21(1); 106 DOI: 10.1186/s12887-021-02567-6
  • Yoshiya Tanaka, Hideto Kameda, Kazuyoshi Saito, Yuko Kaneko, Eiichi Tanaka, Shinsuke Yasuda, Naoto Tamura, Keishi Fujio, Takao Fujii, Toshihisa Kojima, Tatsuhiko Anzai, Chikuma Hamada, Yoshihisa Fujino, Shinya Matsuda, Hitoshi Kohsaka. Response to tocilizumab and work productivity in patients with rheumatoid arthritis: 2-year follow-up of FIRST ACT-SC study. Mod Rheumatol. 2021.01; 31(1); 42-52 DOI: 10.1080/14397595.2019.1709681
  • Yoshiya Tanaka, Masataka Kuwana, Takao Fujii, Hideto Kameda, Yoshinao Muro, Keishi Fujio, Yasuhiko Itoh, Hidekata Yasuoka, Shusaku Fukaya, Konomi Ashihara, Daisuke Hirano, Koichiro Ohmura, Yuya Tabuchi, Hisanori Hasegawa, Ryo Matsumiya, Yuichiro Shirai, Takehisa Ogura, Yumi Tsuchida, Mariko Ogawa-Momohara, Hidehiko Narazaki, Yoshino Inoue, Ippei Miyagawa, Kazuhisa Nakano, Shintaro Hirata, Masaaki Mori. 2019 Diagnostic criteria for mixed connective tissue disease (MCTD): From the Japan research committee of the ministry of health, labor, and welfare for systemic autoimmune diseases. Mod Rheumatol. 2021.01; 31(1); 29-33 DOI: 10.1080/14397595.2019.1709944
  • Sugihara T, Ishizaki T, Onoguchi W, Baba H, Matsumoto T, Iga S, Kubo K, Kamiya M, Hirano F, Hosoya T, Miyasaka N, Harigai M. Effectiveness and safety of treat-to-target strategy in elderly-onset rheumatoid arthritis: a 3-year prospective observational study. Rheumatology (Oxford, England). 2021.01; DOI: 10.1093/rheumatology/keaa922
  • Shunsuke Furuta, Daiki Nakagomi, Yoshihisa Kobayashi, Masaki Hiraguri, Takao Sugiyama, Koichi Amano, Takeshi Umibe, Hajime Kono, Kazuhiro Kurasawa, Yasuhiko Kita, Ryutaro Matsumura, Yuko Kaneko, Keita Ninagawa, Keiju Hiromura, Shin-Ichiro Kagami, Yosuke Inaba, Hideki Hanaoka, Kei Ikeda, Hiroshi Nakajima, LoVAS Collaborators: Hideyuki Iwai. Effect of Reduced-Dose vs High-Dose Glucocorticoids Added to Rituximab on Remission Induction in ANCA-Associated Vasculitis: A Randomized Clinical Trial. JAMA. 2021.01; 325(21); 2178-2187 DOI: 10.1001/jama.2021.6615
  • Natsuki Aokia , Taro Fujikawaa , Natsuka Umezawab , Yoshiyuki Kawashimaa , Taku Itoa , Keiji Hondaa, and Takeshi Tsutsumia. 3Tesla magnetic resonance imaging reveals vasculitis-caused otitis media in a patient with giant cell arteritis ACTA OTO-LARYNGOLOGICA CASE REPORTS. 2021; 6; 6-10 DOI: 10.1001/jama.2021.13863
  • Oba S, Hosoya T, Amamiya M, Mitsumura T, Kawata D, Sasaki H, Kamiya M, Yamamoto A, Ando T, Shimada S, Shirai T, Okamoto T, Tateishi T, Endo A, Aiboshi J, Nosaka N, Yamanouchi H, Ugawa T, Nagaoka E, Oi K, Tao S, Maejima Y, Tanaka Y, Tanimoto K, Takeuchi H, Tohda S, Hirakawa A, Sasano T, Arai H, Otomo Y, Miyazaki Y, Yasuda S. Arterial and Venous Thrombosis Complicated in COVID-19: A Retrospective Single Center Analysis in Japan. Frontiers in cardiovascular medicine. 2021; 8; 767074 DOI: 10.3389/fcvm.2021.767074

2020

  • Tadashi Hosoya, Nikunj M. Shukla, Yuya Fujita, Shiyin Yao, Fitzgerald, S. Lao, Hiroyuki Baba, Shinsuke Yasuda, Howar, B. Cottam, Dennis A. Carson, Tomoko Hayashi, Maripat Corr. Identification of compounds with glucocorticoid sparing effects on suppression of chemokine and cytokine production by rheumatoid arthritis fibroblast-like synoviocytes Frontiers in Pharmacology. 2020.11; DOI: 10.3389/fphar.2020.607713
  • Fujikawa Taro, Honda Keiji, Ito Taku, Kishino Mitsuhiro, Kimura Naoki, Umezawa Natsuka, Hirano Mana, Aoki Natsuki, Kawashima Yoshiyuki, Tsutsumi Takeshi. Enhanced fallopian canal as a potential marker for temporal bone vasculitis LARYNGOSCOPE INVESTIGATIVE OTOLARYNGOLOGY. 2020.11; DOI: 10.1002/lio2.489
  • Tanaka N, Terao C, Nakayama Y, Sasai T, Umezawa N, Yagyu Y, Ito K, Koike R, Nakashima R, Hatta K, Mizoguchi F. Anti-MDA5 antibody-positive dermatomyositis with rapidly progressive interstitial lung disease disguising as anti-synthetase syndrome. Rheumatology. 2020.10; DOI: 10.1093/rheumatology/keaa507
  • Mattias N D Svensson, Martina Zoccheddu, Shen Yang, Gyrid Nygaard, Christian Secchi, Karen M Doody, Kamil Slowikowski, Fumitaka Mizoguchi, Frances Humby, Rebecca Hands, Eugenio Santelli, Cristiano Sacchetti, Kuninobu Wakabayashi, Dennis J Wu, Christopher Barback, Rizi Ai, Wei Wang, Gary P Sims, Piotr Mydel, Tsuyoshi Kasama, David L Boyle, Francesco Galimi, David Vera, Michel L Tremblay, Soumya Raychaudhuri, Michael B Brenner, Gary S Firestein, Costantino Pitzalis, Anna-Karin H Ekwall, Stephanie M Stanford, Nunzio Bottini. Synoviocyte-targeted therapy synergizes with TNF inhibition in arthritis reversal. Science Advances. 2020.06; 6(26); eaba4353 DOI: 10.1126/sciadv.aba4353
  • Wen Shi Lee, Masaru Kato, Eri Sugawara, Michihiro Kono, Yuki Kudo, Michihito Kono, Yuichiro Fujieda, Toshiyuki Bohgaki, Olga Amengual, Kenji Oku, Shinsuke Yasuda, Tomohiro Onodera, Norimasa Iwasaki, Tatsuya Atsumi Protective Role of Optineurin Against Joint Destruction in Rheumatoid Arthritis Synovial Fibroblasts 2020 Sep;72(9):1493-1504; Arthritis & Rheumatology DOI: 10.1002/art.41290
  • Yukino Usui, Yoko Nukui, Ryuji Koike, Shuji Tohda, Ryoichi Saito. Draft Genome Sequence of a Clostridioides difficile Sequence Type 97 Strain Belonging to Hypervirulent Clade 2. Microbiol Resour Announc. 2020.04; 9(14); e00245-20 DOI: 10.1128/MRA.00245-20
  • Nobuya Abe, Masaru Kato, Michihito Kono, Yuichiro Fujieda, Hiroshi Ohira, Ichizo Tsujino, Noriko Oyama-Manabe, Kenji Oku, Toshiyuki Bohgaki, Shinsuke Yasuda, Tatsuya Atsumi. Right ventricular dimension index by cardiac magnetic resonance for prognostication in connective tissue diseases and pulmonary hypertension. Rheumatology. 2020.03; 59(3); 622-633 DOI: 10.1093/rheumatology/kez336
  • Wen Shi Lee, Shinsuke Yasuda, Michihiro Kono, Yuki Kudo, Sanae Shimamura, Michihito Kono, Yuichiro Fujieda, Masaru Kato, Kenji Oku, Tomohiro Shimizu, Tomohiro Onodera, Norimasa Iwasaki, Tatsuya Atsumi. MicroRNA-9 ameliorates destructive arthritis through down-regulation of NF-κ B1-RANKL pathway in fibroblast-like synoviocytes. Clinical immunology. 2020.03; 212; 108348 DOI: 10.1016/j.clim.2020.108348
  • Yokoyama-Kokuryo Waka, Yamazaki Hayato, Takeuchi Tsutomu, Amano Koichi, Kikuchi Jun, Kondo Tsuneo, Nakamura Seiji, Sakai Ryoko, Hirano Fumio, Nanki Toshihiro, Koike Ryuji, Harigai Masayoshi. Identification of molecules associated with response to abatacept in patients with rheumatoid arthritis ARTHRITIS RESEARCH & THERAPY. 2020.03; 22(1); 46 DOI: 10.1186/s13075-020-2137-y
  • Sae Ochi, Kazuyoshi Saito, Fumitaka Mizoguchi, Shigeaki Kato, Yoshiya Tanaka. Insensitivity versus poor response to tumour necrosis factor inhibitors in rheumatoid arthritis: a retrospective cohort study. Arthritis Research & Therapy. 2020.03; 22(1); 41 DOI: 10.1186/s13075-020-2122-5
  • Noda S, Hasegawa H, Tokura M, Mizoguchi F, Kohsaka H. A Case of Systemic Lupus Erythematosus Presenting With Thrombotic Microangiopathy-Induced Cardiomyopathy. Journal of clinical rheumatology : practical reports on rheumatic & musculoskeletal diseases. 2020.02; DOI: 10.1097/RHU.0000000000001353
  • Yuichiro Fujieda, Mototsugu Doi, Takuya Asaka, Masahiro Ota, Ryo Hisada, Naoki Ohnishi, Michihiro Kono, Hiraku Kameda, Daigo Nakazawa, Masaru Kato, Olga Amengual, Masahiko Takahata, Shinsuke Yasuda, Yoshimasa Kitagawa, Tatsuya Atsumi. Incidence and risk of antiresorptive agent-related osteonecrosis of the jaw (ARONJ) after tooth extraction in patients with autoimmune disease. Journal of bone and mineral metabolism. 2020.02; DOI: 10.1007/s00774-020-01089-y
  • Slowikowski K, Nguyen HN, Noss EH, Simmons DP, Mizoguchi F, Watts GFM, Gurish MF, Brenner MB, Raychaudhuri S. CUX1 and I κ B ζ (NFKBIZ) mediate the synergistic inflammatory response to TNF and IL-17A in stromal fibroblasts. Proceedings of the National Academy of Sciences of the United States of America. 2020.02; DOI: 10.1073/pnas.1912702117
  • Kohei Karino, Michihiro Kono, Michihito Kono, Keita Sakamoto, Yuichiro Fujieda, Masaru Kato, Olga Amengual, Kenji Oku, Shinsuke Yasuda, Tatsuya Atsumi. Myofascia-dominant involvement on whole-body MRI as a risk factor for rapidly progressive interstitial lung disease in dermatomyositis. Rheumatology. 2020.01; DOI: 10.1093/rheumatology/kez642
  • Lee WS, Amengual O. B cells targeting therapy in the management of systemic lupus erythematosus Immunological Medicine. 2020.01; DOI: 10.1080/25785826.2019.1698929

2019

  • Yokoyama N, Kawasaki A, Matsushita T, Furukawa H, Kondo Y, Hirano F, Sada KE, Matsumoto I, Kusaoi M, Amano H, Nagaoka S, Setoguchi K, Nagai T, Shimada K, Sugii S, Hashimoto A, Matsui T, Okamoto A, Chiba N, Suematsu E, Ohno S, Katayama M, Migita K, Kono H, Hasegawa M, Kobayashi S, Yamada H, Nagasaka K, Sugihara T, Yamagata K, Ozaki S, Tamura N, Takasaki Y, Hashimoto H, Makino H, Arimura Y, Harigai M, Sato S, Sumida T, Tohma S, Takehara K, Tsuchiya N. Association of NCF1 polymorphism with systemic lupus erythematosus and systemic sclerosis but not with ANCA-associated vasculitis in a Japanese population. Scientific reports. 2019.11;9(1); 16366 DOI: 10.1038/s41598-019-52920-0
  • Yoko Nukui, Alafate Ayibieke, Makoto Taniguchi, Yoshibumi Aiso, Yuka Shibuya, Kazunari Sonobe, Jun Nakajima, Saki Kanehira, Yoshiro Hadano, Shuji Tohda, Ryuji Koike, Ryoichi Saito. Whole-genome analysis of EC129, an NDM-5-, CTX-M-14-, OXA-10- and MCR-1-co-producing Escherichia coli ST167 strain isolated from Japan. J Glob Antimicrob Resist. 2019.09; 18;148-150 DOI: 10.1016/j.jgar.2019.07.001
  • Natsumi Namba, Aya Kawasaki, Ken-Ei Sada, Fumio Hi-rano, Shigeto Kobayashi, Hidehiro Yamada, Hiroshi Furukawa, Kota Shimada, Atsushi Hashimoto, Toshi-hiro Matsui, Kenji Nagasaka, Takahiko Sugihara, Aika Suzuki, Kunihiro Yamagata, Takayuki Sumida, Shigeto Tohma, Sakae Homma, Shoichi Ozaki, Hiroshi Hashimoto, Hirofumi Makino, Yoshihiro Arimura, Masayoshi Harigai, Naoyuki Tsuchiya. Association of MUC5B promoter polymorphism with interstitial lung disease in myeloperoxidase-antineutrophil cytoplasmic antibody-associated vasculitis. Ann Rheum Dis. 2019.08;78(8):1144-1146 DOI: 10.1136/annrheumdis-2018-214263
  • Takashi Okumura, Yumi Horie, Chen-Yi Lai, Huan-Ting Lin, Hiro-fumi Shoda, Bunki Natsumoto, Keishi Fujio, Eri Kumaki, Tsubasa Okano, Shintaro Ono, Kay Tanita,Tomohiro Morio, Hirokazu Kanegane, Hisanori Hasegawa, Fumitaka Mizoguchi, Kimito Kawahata, Hi-toshi Kohsaka, Hiroshi Moritake, Hiroyuki Nunoi, Hironori Waki, Shin-Ichi Tamaru, Takayoshi Sasako,Toshimasa Yamauchi, Takashi Kadowaki, Hiroyuki Tanaka, Sachiko Kitanaka, Ken Nishimura, Manami Ohtaka, Mahito Nakanishi, Makoto Otsu. Robust and highly efficient hiPSC generation from patient non-mobilized peripheral blood-derived CD34+ cells using the auto-erasable Sendai virus vector. Stem Cell Res Ther. 2019.06; 10(1); 185 DOI: 10.1186/s13287-019-1273-2
  • H Sasaki, A Takamura, K Kawahata, T Takashima, K Imai, T Morio, H Kohsaka. Peripheral blood lymphocyte subset repertoires are biased and reflect clinical features in patients with dermatomyositis. Scand J Rheumatol. 2019.05; 48(3); 225-229 DOI: 10.1080/03009742.2018.1530371
  • Matsuda Y, Itabashi M, Tachibana Y, Sugihara T, Sakashita Y, Matsubara T, Murayama S, Yumura W, Shimizu A, Takei T, Arai T. Citrullinated histone H3 expression in anti-neutrophil cytoplasmic antibody-associated vasculitis in older Japanese autopsy patients. Geriatrics & gerontology international. 2019.03; 19(3); 259-264 DOI: 10.1111/ggi.13596
  • Kamiya M, Mizoguchi F, Takamura A, Kimura N, Kawahata K, Kohsaka H. A new in vitro model of polymyositis reveals CD8+ T cell invasion into muscle cells and its cytotoxic role. Rheumatology (Oxford). 2020.01;59(1):224-232 DOI: 10.1093/rheumatology/kez248
  • Miyazawa R, Tanei R, Tsuchida M, Sugihara T. MPO-ANCA-positive cutaneous polyarteritis nodosa with livedo racemosa arising from immune-deposit-positive necrotizing vas-culitis. G Ital Dermatol Venereol. 2019.01 DOI: 10.23736/S0392-0488.18.05956-4
  • Kameda Hideto, Fujii Takao, Nakajima Ayako, Koike Ryuji, Sagawa Akira, Kanbe Katsuaki, Tomita Tetsuya, Harigai Masayoshi, Suzuki Yasuo, Japan College of Rheumatology subcommittee on the guideline for the use of methotrexate in patients with rheumatoid arthritis. Japan College of Rheumatology guideline for the use of methotrexate in patients with rheumatoid arthritis Modern Rheumatology. 2019.01; 29(1); 31-40 DOI: 10.1080/14397595.2018.1472358
  • Masatoshi Takagi, Chitose Ogawa, Yuki Aoki-Nogami, Tomoko Iehara, Eri Ishibashi, Minoru Imai, Tetsuro Kihara, Kiyoshi Nobori, Kazuhisa Hasebe, Shuki Mizutani, Toshimi Kimura, Masashi Nagata, Masato Yasuhara, Kenichi Yoshimura, Pariko Yorozu, Hajime Hosoi, Ryuji Koike. Phase I clinical study of oral olaparib in pediatric patients with refractory solid tumors: study protocol. BMC Pediatr. 2019.01; 19(1); 31 DOI: 10.1186/s12887-019-1409-7

2010年～2020年　業績(英語)