TMDU Center for Infectious Disease Education and Analysis (TCIDEA) by Yoshiaki Gu, Tomoko Yazawa and Hiroaki Takeuchi
Research Activities
TMDU-Committed to Pioneering Medical Research
Successful murine model of dermatomyositis reveals underlying immune system involvement by Naoko Okiyama
Towards a Better Understanding of Endothelial Cell Transformation in Cancer Progression by Tetsuro Watabe, Miho Kobayashi and Kazuki Takahashi
Informatics and Artificial Intelligence for Biomedicine -Present and the Next Generation- by Yoshikazu Nakajima
The hidden identity of leukemia by Masatoshi Takagi and Akira Nishimura
CiDRE renders alveolar macrophages susceptible to SARS-CoV-2 invasion by Takashi Satoh and Yuichi Mitsui
Self vs Non-self discrimination in antiviral immune response by Kazuki Kato
Breaking through barriers by Hirokazu Kaji and Takeshi Hori
A secret passage for mutant protein to invade the brain by Hitoshi Okazawa
Link between chronic kidney disease and cardiovascular disease explained by Shintaro Mandai
Deciphering the Secrets of Brain Development by Naofumi Uesaka
Placenta transmits parental information to offspring by Joji Kusuyama
The “Wishbone” Charm that Restores the Hope for Bone Regeneration by Takashi Ono and Yuji Ishida
Protein Secrets Unveiled: New molecular insight of protein–protein interactions by Miki Hara-Yokoyama
New insights into the development of Parkinson’s disease in the brain by Satoru Torii
Toward understanding mechanisms of chronic inflammation by Yumiko Oishi
Can ChatGPT diagnose your condition? Not yet by Koji Fujita
Nano Drug Delivery System (DDS) for mRNA Therapeutics by Satoshi Uchida
Killer smile? An oral pathogen increases heart attack damage by Yasuhiro Maejima
A new, promising weapon in the fight against HIV by Hirokazu Tamamura
Pre-basophils: a basophil origin story by Kensuke Miyake
A new mechanism encouraging the brain to self-repair after an ischemic stroke by Takashi Shichita
Toward understanding diversity of various disorder-specific myeloid cells by Takashi Satoh
Evidence showing the ‘loosening of associations’ found in schizophrenia by Hidehiko Takahashi
Biomolecular Analyses Now Have an Expanded Chemical Toolkit by Yuki Sakata
Filling the Gap Between Benchside and Bedside: AI-accelerated Target Discovery to Therapeutic Development by Hideyuki Shimizu
From grave to cradle: collagen-induced gut cell reprogramming by Shiro Yui and Sakurako Kobayashi
Stopping the spread: targeting tumor metastasis by Tetsuro Watabe, Katarzyna A. Podyma-Inoue and Kazuki Takahashi
The world’s first Mini Organ transplantation to a patient with “Ulcerative Colitis (UC)” by yuichi Okamoto, Tomohiro Mizutani and Hiromichi Shimizu
Body versus brain: New evidence for an autoimmune cause of schizophrenia by Hiroki Shiwaku
Tears in Tokyo: Muscle–tendon injuries during Olympic competition can spell heartbreak by Hideyuki Koga
Mind your Qs: polyQ-binding protein 5 scaffolds the nucleolus by Hitoshi Okazawa
Building Better Gas-phase Biosensors for Fight Against Diseases by Kenta Iitani
Molecular mechanisms underlying hereditary Parkinson's disease by Noriyuki Matsuda
Minimally Invasive Drug and Cell Delivery Systems Targeting the Posterior Segment of the Eye by Hirokazu Kaji
Biochemistry and molecular genetics to understand life and diseases by Katsumori Segawa
Expanding the arsenal of drugs against COVID-19 by Hirokazu Tamamura
A Matter of Concentration: Molecular Mechanisms of Water Homeostasis by Fumiaki Ando
Move over muscles, it’s time for tendons to be in the spotlight by Hiroshi Asahara & Ryo Nakamichi
Clinical application of the digital dentures by Manabu Kanazawa
Precision Engineering Design for Biofunctional Repair and Support by Masashi Ikeuchi
Xanthan gum-based fluid thickener can help decrease blood glucose levels by Haruka Tohara, Sayaka Katagiri & Yuuki Nagasawa
Transistors help identify cancer cell markers by Yuji Miyahara
A novel drug suppresses muscle inflammation and restores muscle weakness by Shinsuke Yasuda & Mari Kamiya
Dental OCT - A Novel Imaging Technique without the use of X rays by Yasushi Shimada
Drilling into the Dental Secrets of Edo-era Japanese Bacterial Genomes by Takeaki Sudo & Takahiko Shiba
Seeing Lipids More Deeply with Mass Spectrometry by Takehiko Sasaki & Shin Morioka
Periodontal Regeneration with Cell Sheet Technology by Takanori Iwata
Predicting the Progression of Rheumatoid Arthritis by Yuta Kochi
Targeting Necroptosis for Inflammatory Myopathies by Shinsuke Yasuda & Mari Kamiya
Pathologic myopia - The major cause of visual impairment by Kyoko Ohno-Matsui
Infusion of 3D cellular structures might repair damaged intestine by Shiro Yui & Satoshi Watanabe
Osteoarthritis of the knee is evaluated with 3DMRI and regenerated with stem cells by Ichiro Sekiya
Prediction and detection of atrial fibrillation for reducing cardiogenic stroke by Tetsuo Sasano
Machine learning to synthesize endoscopy findings in ulcerative colitis by Kento Takenaka
When mad AIOLOS drags IKAROS down: a novel pathogenic mechanism by Tomohiro Morio & Motoi Yamashita
A new agent for the brain diseases: mRNA by Keiji Itaka & Yuta Fukushima
Social pathways between oral and general health by Jun Aida
Ventilating the rectum to support respiration by Takanori Takebe
“On-skin-pancreas” technology for precision medicine in diabetes by Akira Matsumoto
No IgA leads to intestinal inflammation in mice by Takahiro Adachi
A new polarized fluorescent probe for revealing architectural dynamics of living cells by Sumio Terada, Keisuke Sato & Ayana Sugizaki
Restoring healthy gut bacteria through blood stem cell transplantation by Hirokazu Kanegane
The Xa Factor : Pushing Back on Atherosclerosis by Yasuhiro Maejima
Jigsaw-Shaped Peptide Solves Tissue Regeneration Puzzle by Itsuki Ajika
One protein to rule them all: a central target for treating dementia by Hitoshi Okazawa & Hikari Tanaka
Getting You Moving Again: A Possible New Treatment for Joint Issues by Hiroshi Asahara & Yoshiaki Ito
Using Mice to Open the Way to Prevent Blocked Arteries by Masayuki Yoshida
Bringing cells closer to form new tissues by Nobuhiko Yui
Lighting the LAMP to Reveal Mystery of Lysosomes by Miki Hara-Yokoyama
HIV has been Had by Hirokazu Tamamura
Super-Enhancers: The Villain Fueling Certain Cancers by Johji Inazawa & Yasuyuki Gen
Genetic variant linked to prognosis of chronic hypersensitivity pneumonitis by Yasunari Miyazaki
From blood to brain: delivering nucleic acid therapy to the CNS by Takanori Yokota
Message from the President – 3 Policies of TMDU Research
“My Medicine” with organoids– Predicting the future of liver-safe drugs by Takanori Takebe
Introducing the M&D Data Science Center - A center of gravity for biomedical data science in the world by Satoru Miyano
Generation of three-dimensional heart organoids by Fumitoshi Ishino
How poor oral hygiene may result in metabolic syndrome by Sayaka Katagiri
Message from the Executive Director (Research)
The natural artistry of disease: a wintry landscape in the eye by Koju Kamoi
Reversible Stickiness is Something to Smile About by Nobuhiko Yui
A new molecular guardian of intestinal stem cells by Toshiaki Ohteki
Nothing but the Truth in the Fight Against Cancer by Hiroshi Asahara
How Cells Decide the Way They Want to Recycle Their Content by Shigeomi Shimizu
Human Lifelong Immunity Depends on APRIL by Kohsuke Imai
β-AR Agonist Therapy Puts the Brakes on Oral Cancer Progression by Tetsuro Watabe