業績

2022年度

  1. Matsuoka K, Fujii T, Okamoto R, Yamada A, Kunisaki R, Matsuura M, Watanabe K, Shiga H, Takatsu N, Bamba S, Mikami Y, Yamamoto T, Shimoyama T, Motoya S, Torisu T, Kobayashi T, Ohmiya N, Saruta M, Matsuda K, Matsumoto T, Nakase H, Maemoto A, Shinzaki S, Murata Y, Yoshigoe S, Sasaki A, Yajima T, Hisamatsu T. Characteristics of adult patients newly diagnosed with Crohn’s disease: interim analysis of the nation-wide inception cohort registry study of patients with Crohn’s disease in Japan (iCREST-CD). J Gastroenterol. 2022.11; 57(11); 867-878.PMID: 35930087 DOI:  10.1007/s00535-022-01907-2

  2. Takahashi J, Mizutani T, Sugihara HY, Nagata S, Kato S, Hiraguri Y, Takeoka S, Tsuchiya M, Kuno R, Kakinuma S, Watanabe M, Okamoto R. Suspension culture in a rotating bioreactor for efficient generation of human intestinal organoids. Cell Reports Methods. 2022.11; 2(11); 100337. PMID: 36452871 DOI: 10.1016/j.crmeth.2022.100337

  3. Kaneko S, Kurosaki M, Kurisu A, Akita T, Tanaka J, Kanto T. Impact of antiviral therapy for disease progression and non-invasive liver fibrosis index in patients with chronic hepatitis C: Markov chain model analysis. Hepatology Research. 2022.08; 52(8); 665-676. PMID: 35591759 DOI: 10.1111/hepr.13794

  4. Kaneko S, Tsuchiya K, Yasui Y, Tanaka Y, Inada K, Ishido S, Kirino S, Yamashita K, Hayakawa Y, Nobusawa T, Matsumoto H, Kakegawa T, Higuchi M, Takaura K, Tanaka S, Maeyashiki C, Tamaki N, Takahashi Y, Nakanishi H, Irie T, Ariizumi SI, Kurosaki M, Izumi N. Conversion surgery for hepatocellular carcinoma after tyrosine kinase inhibitor treatment. JGH open : an open access journal of gastroenterology and hepatology. 2022.05; 6(5); 301-308. PMID: 35601130 DOI: 10.1002/jgh3.12735

  5. Takenaka K, Kawamoto A, Okamoto R, Watanabe M, Ohtsuka K. Artificial intelligence for endoscopy in inflammatory bowel disease. Intest Res. 2022.04; 20(2); 165-170. PMID: 34986607 DOI: 10.5217/ir.2021.00079

  6. Kaneko S, Tsuchiya K, Yasui Y, Tanaka Y, Inada K, Ishido S, Kirino S, Yamashita K, Hayakawa Y, Nobusawa T, Matsumoto H, Kakegawa T, Higuchi M, Takaura K, Tanaka S, Maeyashiki C, Tamaki N, Takahashi Y, Nakanishi H, Irie T, Ariizumi S, Kurosaki M, Izumi N. Conversion surgery for hepatocellular carcinoma after tyrosine kinase inhibitor treatment. JGH Open. 2022.04; 6(5); 301-308. PMID: 35601130 DOI: 10.1002/jgh3.12735

  7. Stidham R. W, Takenaka K. Artificial Intelligence for Disease Assessment in Inflammatory Bowel Disease: How Will it Change Our Practice? Gastroenterology. 2022.04; 162(5); 1493-1506 PMID: 34995537 DOI: 10.1053/j.gastro.2021.12.238

  8. Kaneko S, Kurosaki M, Tsuchiya K, Yasui Y, Hayakawa Y, Inada K, Tanaka Y, Ishido S, Kirino S, Yamashita K, Nobusawa T, Matsumoto H, Kakegawa T, Higuchi M, Takaura K, Tanaka S, Maeyashiki C, Tamaki N, Takahashi Y, Nakanishi H, Izumi N. Clinical evaluation of Elecsys PIVKA-II for patients with advanced hepatocellular carcinoma. PLoS One. 2022.03; 17(3); e0265235. PMID: 35271670 DOI: 10.1371/journal.pone.0265235

  9. Matsuda H, Nibe-Shirakihara Y, Tamura A, Aonuma E, Arakawa S, Otsubo K, Nemoto Y, Nagaishi T, Tsuchiya K, Shimizu S, Ma A, Watanabe M, Uo M, Okamoto R, Oshima S. Nickel particles are present in Crohn’s disease tissue and exacerbate intestinal inflammation in IBD susceptible mice. Biochem Biophys Res Commun. 2022.02; 592; 74-80. PMID: 35032835 DOI: 10.1016/j.bbrc.2021.12.111

  10. Higuchi M, Tamaki N, Kurosaki M, Inada K, Kirino S, Yamashita K, Hayakawa Y, Osawa L, Takaura K, Maeyashiki C, Kaneko S, Yasui Y, Takahashi Y, Tsuchiya K, Nakanishi H, Itakura J, Loomba R, Enomoto N, Izumi N.. Longitudinal association of magnetic resonance elastography-associated liver stiffness with complications and mortality Aliment Pharmacol Ther.. 2022.02; 55(3); 292-301. PMID: 34927277 DOI: 10.1111/apt.16745

  11. Suzuki K, Kakuta Y, Naito T, Takagawa T, Hanai H, Araki H, Sasaki Y, Sakuraba H, Sasaki M, Hisamatsu T, Motoya S, Matsumoto T, Onodera M, Ishiguro Y, Nakase H, Andoh A, Hiraoka S, Shinozaki M, Fujii T, Katsurada T, Kobayashi T, Fujiya M, Otsuka T, Oshima N, Suzuki Y, Sato Y, Hokari R, Noguchi M, Ohta Y, Matsuura M, Kawai Y, Tokunaga K, Nagasaki M, Kudo H, Minegishi N, Okamoto D, Shimoyama Y, Moroi R, Kuroha M, Shiga H, Li D, McGovern D P B, Kinouchi Y, Masamune A. Genetic Background of Mesalamine-induced Fever and Diarrhea in Japanese Patients with Inflammatory Bowel Disease. Inflamm Bowel Dis. 2022.01; 28(1); 21-31. PMID: 33501934 DOI: 10.1093/ibd/izab004

  12. Sekiguchi S, Tsuchiya K, Yasui Y, Inada K, Kirino S, Yamashita K, Hayakawa Y, Osawa L, Higuchi M, Takaura K, Maeyashiki C, Kaneko S, Tamaki N, Nakanishi H, Itakura J, Takahashi Y, Asahina Y, Okamoto R, Kurosaki M, Izumi N. Clinical usefulness of geriatric assessment in elderly patients with unresectable hepatocellular carcinoma receiving sorafenib or lenvatinib therapy. Cancer Rep (Hoboken). 2022.11; 5(11); e1613. PMID: 35302279 DOI: 10.1002/cnr2.1613

  13. Kobayashi S, Ogasawara N, Watanabe S, Yoneyama Y, Kirino S, Hiraguri Y, Inoue M, Nagata S, Okamoto-Uchida Y, Kofuji S, Shimizu H, Ito G, Mizutani T, Yamauchi S, Kinugasa Y, Kano Y, Nemoto Y, Watanabe M, Tsuchiya K, Nishina H, Okamoto R, Yui S. Collagen type I-mediated mechanotransduction controls epithelial cell fate conversion during intestinal inflammation. Inflamm Regen. 2022.11; 42(1); 49. PMID: 36443773 DOI: 10.1186/s41232-022-00237-3

  14. Kawamoto A, Fujii T, Mitani R, Suzuki Y, Yauchi T, Okamoto R. Serum Levels of Infliximab Biosimilar in a Child Delivered From a Mother Treated for Ulcerative Colitis. Inflamm Bowel Dis. 2022.08; 28(8); 1298-1299. PMID: 35700275 DOI: 10.1093/ibd/izac111

  15. Schweiger P. J, Le Bouteiller M, Yui S, Thodberg M, Clement D, Jensen K. B. Extracellular matrix interactions provide tumor cells with an escape mechanism for commitment to differentiation. Gastroenterology. 2022 Dec;163(6):1688-1690.e3. PMID: 36037993 DOI: 10.1053/j.gastro.2022.08.036

  16. Takishima K, Maeda Y, Ogata N, Misawa M, Mori Y, Homma M, Nemoto T, Miyata Y, Akimoto Y, Mochida K, Takashina Y, Tanaka K, Ichimasa K, Nakamura H, Sasanuma S, Kudo T, Hayashi T, Wakamura K, Miyachi H, Baba T, Ishida F, Ohtsuka K, Kudo S. Beyond complete endoscopic healing: Goblet appearance using an endocytoscope to predict future sustained clinical remission in ulcerative colitis. Dig Endosc. 2022.07; 34(5); 1030-1039. PMID: 34816494 DOI: 10.1111/den.14202

  17. Hibiya S, Ohtsuka K, Takenaka K, Kawamoto A, Matsuyama Y, Udagawa Y, Motobayashi M, Shimizu H, Fujii T, Saito E, Nagahori M, Okamoto R, Watanabe M. Mucosal healing of small intestinal stricture is associated with improved prognosis post-dilation in Crohn’s disease. BMC Gastroenterol. 2022.05; 22(1); 218. PMID: 35508963 DOI: 10.1186/s12876-022-02300-2

  18. Kobayashi M, Ryozawa S, Ohtsuka K, Tanabe M, Okamoto R. A convenient and reliable method for endoscopic mapping biopsy of cholangiocarcinoma using a double-lumen cytology device. VideoGIE. 2022.05; 7(5); 182-184. PMID: 35585892 DOI: 10.1016/j.vgie.2022.01.009

  19. Maeda Y, Kudo S, Ogata N, Misawa M, Iacucci M, Homma M, Nemoto T, Takishima K, Mochida K, Miyachi H, Baba T, Mori K, Ohtsuka K, Mori Y. Evaluation in real-time use of artificial intelligence during colonoscopy to predict relapse of ulcerative colitis: a prospective study. Gastrointest Endosc. 2022.04; 95(4); 747-756.e2. PMID: 34695422 DOI: 10.1016/j.gie.2021.10.019

  20. Watanabe S, Kobayashi S, Ogasawara N, Okamoto R, Nakamura T, Watanabe M, Jensen K B, Yui S. Transplantation of intestinal organoids into a mouse model of colitis. Nat Protoc. 2022.03; 17(3); 649-671. PMID: 35110738 DOI: 10.1038/s41596-021-00658-3

  21. Kirino S, Tamaki N, Kurosaki M, Kaneko S, Inada K, Tanaka Y, Ishido S, Yamashita K, Nobusawa T, Matsumoto H, Hayakawa Y, Kakegawa T, Higuchi M, Takaura K, Tanaka S, Maeyashiki C, Yasui Y, Takahashi Y, Tsuchiya K, Nakanishi H, Okamoto R, Izumi N. Alanine aminotransferase levels as therapeutic targets after nucleotide/nucleoside analog therapy in patient with chronic hepatitis B. HEPATOLOGY RESEARCH. 2022.10; 53(1); 35-42. PMID: 36117296 DOI: 10.1111/hepr.13839

  22. Kawamoto A, Takenaka K, Hibiya S, Ohtsuka K, Okamoto R, Watanabe M. Serum Leucine-Rich alpha(2) Glycoprotein: A Novel Biomarker For Small Bowel Mucosal Activity in Crohn’s Disease CLINICAL GASTROENTEROLOGY AND HEPATOLOGY. 2022.05; 20(5); E1196-E1200. PMID: 34216822 DOI: 10.1016/j.cgh.2021.06.036