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Home  > Department of Neuropathology

Department of Neuropathology

The goals of our department are to understand the mechanisms underlying neurodegenerative diseases and to develop effective therapeutics for such intractable disorders. At the present moment, Alzheimer’s disease, other dementias, polyglutamine diseases, and developmental disorders related to PQBP1 are the main targets of our laboratory. For more than 15 years, we have been focusing on the proteome and transcriptome analyses of cellular and animal models of polyglutamine diseases and have obtained novel molecules that are critically involved in the pathomechanisms. Therefore, we are now at the starting point actually to link our researches to clinical application. We will summarize the contents of publication in this year.