Yutaka Hata organizes the courses of medical biochemistry, molecular cellular biology, and human molecular genetics for medical students. His group is studying on the tumor suppressor signaling, which plays versatile roles in not only cancer but also other human diseases.
This site will provide information about the ongoing research in the laboratory, a list of recent publications, a list of present lab personnel, and contact information.
To learn more about our laboratory, please feel free to contact Dr. Yutaka Hata directly by addressing an email to yuhammch ad mark tmd. ac. jp.
Research in the laboratory is focused on the tumor suppressor Hippo pathway and RASSF proteins. Our research is concentrated in three areas: (1) Understanding the impact of the dysfunction of Hippo pathway on the malignant properties of cancer cells (stemness, invasiveness, and drug resistance). (2) Identification of biological events which RASSF proteins mediate under physiological and pathological conditions and elucidating the underlying molecular mechanisms. (3) Searching for the reagents which inhibit Hippo pathway and the way to recover the functions of Hippo pathway and RASSF in cancer cells.