Publications
1. Yonashiro R., Eguchi K., Wake M., Takeda N., and Nakayama K.* Pyruvate dehydrogenase PDH-E1β is downregulated under prolonged hypoxic conditions and controls tumor progression by altering the metabolic status of cancer cells. Cancer Res.(2018) in press
2. Gudla PR., Nakayama K., Pegoraro G., Misteli T. SpotLearn: Convolutional Neural Network for Detection of Fluorescence In Situ Hybridization (FISH) Signals in High-Throughput Imaging Approaches. Cold Spring Harb Symp Quant Biol. (2017) in press
3. Kikuchi D., Tanimoto K., and Nakayama K.* CREB is activated by ER stress and modulates the unfolded protein response by regulating the expression of IRE1α and PERK. Biochem. Biophys. Res. Commun., 469, 243-250, (2016)
4. Katsuta E, Tanaka S, Mogushi K, Shimada S, Akiyama Y, Aihara A, Matsumura S, Mitsunori Y, Ban D, Ochiai T, Kudo A, Fukamachi H, Tanaka H, Nakayama K., Arii S, Tanabe M. CD73 as a therapeutic target for pancreatic neuroendocrine tumor stem cells. Int. J. Oncol., 48, 657-669, (2016)
5. Kikuchi D., Minamishima YA., and Nakayama K.* Prolyl-hydroxylase PHD3 interacts with pyruvate dehydrogenase (PDH)-E1beta and regulates the cellular PDH activity. Biochem. Biophys. Res. Commun. 451, 288-294, (2014)
6. Nakayama K.* CREB and NF-kB are activated during prolonged hypoxia and cooperatively regulate the induction of matrix metalloproteinase MMP1. J. Biol. Chem. 288, 22584-22595, (2013)
7. Arima N., Uchida Y., Yu R., Nakayama K., Nishina H. Acetylcholine receptors regulate gene expression that is essential for primitive streak formation in murine embryoid bodies. Biochem. Biophys. Res. Commun. 435, 447-453, (2013)
8. Muramatsu S., Tanaka S., Mogushi K., Adikrisna R., Aihara A., Ban D., Ochiai T., Irie T., Kudo A., Nakamura N., Nakayama K., Tanaka H., Yamaoka S., Arii S. Visualization of stem cell features in human hepatocellular carcinoma enlightened in vivo significance of tumor-host interaction and clinical implication. Hepatology 58, 218-228, (2013)
9. Sato M., Sakota M., and Nakayama K.* Human PRP19 interacts with prolyl-hydroxylase PHD3 and inhibits cell death in hypoxia. Exp. Cell Res. 318, 2871-2882, (2010)
2. Gudla PR., Nakayama K., Pegoraro G., Misteli T. SpotLearn: Convolutional Neural Network for Detection of Fluorescence In Situ Hybridization (FISH) Signals in High-Throughput Imaging Approaches. Cold Spring Harb Symp Quant Biol. (2017) in press
3. Kikuchi D., Tanimoto K., and Nakayama K.* CREB is activated by ER stress and modulates the unfolded protein response by regulating the expression of IRE1α and PERK. Biochem. Biophys. Res. Commun., 469, 243-250, (2016)
4. Katsuta E, Tanaka S, Mogushi K, Shimada S, Akiyama Y, Aihara A, Matsumura S, Mitsunori Y, Ban D, Ochiai T, Kudo A, Fukamachi H, Tanaka H, Nakayama K., Arii S, Tanabe M. CD73 as a therapeutic target for pancreatic neuroendocrine tumor stem cells. Int. J. Oncol., 48, 657-669, (2016)
5. Kikuchi D., Minamishima YA., and Nakayama K.* Prolyl-hydroxylase PHD3 interacts with pyruvate dehydrogenase (PDH)-E1beta and regulates the cellular PDH activity. Biochem. Biophys. Res. Commun. 451, 288-294, (2014)
6. Nakayama K.* CREB and NF-kB are activated during prolonged hypoxia and cooperatively regulate the induction of matrix metalloproteinase MMP1. J. Biol. Chem. 288, 22584-22595, (2013)
7. Arima N., Uchida Y., Yu R., Nakayama K., Nishina H. Acetylcholine receptors regulate gene expression that is essential for primitive streak formation in murine embryoid bodies. Biochem. Biophys. Res. Commun. 435, 447-453, (2013)
8. Muramatsu S., Tanaka S., Mogushi K., Adikrisna R., Aihara A., Ban D., Ochiai T., Irie T., Kudo A., Nakamura N., Nakayama K., Tanaka H., Yamaoka S., Arii S. Visualization of stem cell features in human hepatocellular carcinoma enlightened in vivo significance of tumor-host interaction and clinical implication. Hepatology 58, 218-228, (2013)
9. Sato M., Sakota M., and Nakayama K.* Human PRP19 interacts with prolyl-hydroxylase PHD3 and inhibits cell death in hypoxia. Exp. Cell Res. 318, 2871-2882, (2010)