Research
Our scientific and academic activities encompass a wide spectrum, from basic to clinical research. Our goal is a comprehensive resolution of childhood health issues through the development of innovative diagnostic, therapeutic, and preventive strategies.
Hematology/ Oncology/Immunology
- Pathophysiological Analysis of Infant Acute Lymphoblastic Leukemia
- Pathogenesis and Therapeutic Development for Neuroblastoma
- Development of Gene Therapy for Ataxia–Telangiectasia
- Development of Diagnostic Methods for Leukemia Based on 3D Genome Architecture and Nuclear Localization
- Development of Virus-Specific T-Cell Therapy and CAR-NK Cell Therapy
- Identification of Causative Genes in Primary Immunodeficiency Diseases
Cardiology
- Elucidation of the Pathophysiology of Pulmonary Hypertension and Development of Novel Therapeutic Strategies
- Clinical Research on Pulmonary Hypertension
- AI-Based Imaging Diagnosis for Cardiovascular Diseases
Neurology
- Establishment of Newborn Screening Methods for Spinal Muscular Atrophy (SMA) and Longitudinal Changes in Electrophysiological Findings in Treated SMA Patients
- Evaluation of Adrenocortical Function in Patients with West Syndrome Undergoing ACTH Therapy
- Establishment of Pediatric Reference Values and Clinical Application in Central Nervous System Disorders for a Cerebellar Motor-Learning Assessment System Using Prism Adaptation
- Study on the Association Between Serum Copper and Zinc Levels and Epilepsy Severity
Endocrinology and Metabolism
- Elucidation of the Molecular Mechanisms of Sex Differentiation and Gonadal Development
- Establishment of Novel Diagnostic and Therapeutic Strategies and Biomarkers for 21-Hydroxylase Deficiency (21OHD)
- Molecular Pathophysiology of Congenital Endocrine Disorders
- Elucidating the Mechanisms Linking the Intrauterine Environment to Disease Development Using Umbilical Cord–Derived Mesenchymal Stem Cells
Rheumatology/Nephrology
- Molecular Immunological Analysis of Pediatric Rheumatic Diseases
- Data Analysis of Pediatric Rheumatic Diseases Using an Immunodeficiency Registry
- Immunological Evaluation of Infants Born to Mothers With Immune-Mediated Diseases to Establish Safe and Effective Vaccination Guidelines
- Pathophysiological Analysis of Juvenile Idiopathic Arthritis Toward Personalized Medicine
- Immunological Pathogenesis of Pediatric Kidney Diseases
- Pathophysiological Analysis of TINU Syndrome
Neonatology
- Basic Research on Changes in the Profiles of Umbilical Cord Blood and Umbilical Cord–Derived Mesenchymal Stem Cells Influenced by the Intrauterine Environment
- Analysis of Changes in Deciduous Tooth Pulp Stem Cell Profiles in Children With Cerebral Palsy Caused by Periventricular Leukomalacia
- Basic Research on the Relationship Between Physical Growth in Infancy and the Gene Expression Profiles of Umbilical Cord–Derived Mesenchymal Stem Cells
Allergy
- Clinical Characteristics and Pathophysiology of Allergic Diseases Associated With Primary Immunodeficiency Diseases and Inflammatory/Immune Dysregulation Disorders
Principal investigators
Department of Pediatrics and Developmental Biology
All medical staffs are Board certified pediatrician
| Professor | Masatoshi Takagi, PhD., MD. | (Hematology/ Oncology/Immunology) | m.takagi.ped(at)tmd.ac.jp |
|---|---|---|---|
| Associate Professor | Takeshi Isoda, PhD., MD. | (Hematology/ Oncology/Immunology) | tisoda.ped@md.isct.ac.jp |
| Junior Associate Professor | Takahiro Kamiya, PhD., MD. | (Hematology/ Oncology/Immunology) | kamiya.ped(at)tmd.ac.jp |
| Assistant Professor | Kei Takasawa, PhD., MD. | (Endocrinology) | ktakasawa.ped(at)tmd.ac.jp |
Department of Child Health and Development
| Professor | Hirokazu Kanegane, PhD., MD. | (Hematology/ Oncology/Immunology) | hkanegane.ped(at)tmd.ac.jp |
|---|
Department of Pediatrics, Neonatal and Maternal Medicine
| Professor | Masaki Shimizu, PhD., MD. | (Rheumatology/Nephrology) | mshimizu.ped(at)tmd.ac.jp |
|---|

