News
2025
10-12 Dec, 2025
Masa was awarded the Best Presentation Award in the 54th Annual Meeting of the Japanease Society for Immunology @Himeji
Congrats!
Best Presentation Award 2025 19-20 June, 2025
Masa was awarded the Best Presentation Prize in the 2nd Annual meeting of Japanease Cytokine Society @Osaka
Congrats!
7 May, 2025
Ohsumi-sensei, a Nobel laureate, dropped by our lab, discussed our recent work, and encouraged team members!!
Great opportunity to all team members!
Apr, 2025
Riko Koizumi-san (Kitasato U) and Wu Tong-kun (Chuo U) join our team!
1 Apr, 2025
Masa has been appointed as a lecturer in Medical Research Laboratory. Congrats!
27 Mar, 2025
On the final day with Nishimoto-san @ Science Tokyo, we held a lunch party.
She had provided substantial support for the animal work in our team, making a significant contribution.
She will be joining Tohara-sensei's Lab at U Tokyo. Best of luck to her!
17 Mar, 2025
A collaborative work has been posted @biorxiv.
"Early-peaking caspase-7 activity at the plasma membrane drives apoptotic phosphatidylserine exposure”
Congratulations to Taira-san and Shinoda-san from Miura-sensei's Lab on this exciting discovery!
bioRxiv 11 Mar, 2025
Yugo and Chery-san joined an annual meeting of Medical Reseach Laboratory.
Yugo has been awarded the best paper prize in 2024 @MRL. Congrtas!
11 Mar, 2025
Our TMEM63/OSCA work @FEBS Letters has been featured as an Editor's choice and the cover image of the issue.
Congrats Yugo and team!.
Feb, 2025
Masa Nagata has been awarded for SECOM Science and Technology Foundation Grant.
Congrats Masa!.
20-21 Jan, 2025
We joined annual cell death colloquium @Kyoto U.
Yugo gave a talk about membrane structure-responsive lipid scramblase TMEM63B.
2024
3 Dec, 2024
A paper regarding TMEM63/OSCA protein family members is accepted @ FEBS Letters.
We addressed the evolutionary aspects of TMEM63/OSCA family members regarding membrane structure-sensitive phospholipid scramblase activity.
Its scramblase activity is conserved in vertebrates but not in plant OSCA1.1, indicating evolutionary adaptation.
Congrats! Yugo and team!
FEBS Letters 22 Nov, 2024
We hosted the 654th MRI Seminar and had Dr. Katsuhiko Hayashi from Osaka.
He shared recent work on reconstitution of germ cell development and also sex conversion in vitro. Mind blowing!
He is one of the 100 Most Influential People of 2024 in TIME journal.
The lecture taught us that great success is built on ordinary experiments conducted in a step-by-step manner.
We need grit!
TIME: Dr. Katsuhiko Hayashi 15 Nov, 2024
We hosted the 3rd Medical Chemistry Seminar and had Dr. Yasutaka Okabe from Osaka.
He shared recent work on mucosiliarly clearance system in airway host defence. Great talk!
Dr. Yasutaka Okabe 12 Nov, 2024
The 14th IFReC international symposium on immunology.
IFReC Symposium 1 Nov, 2024
Yugo Miyata has been promoted to Lecturer.
Congrats, Yugo!
30 Oct, 2024
Press Release is out!
Press Release Oct, 2024
TMEM63B paper is featured in a Research Briefing @Nat Struct Mol Biol.
TMEM63B Research Briefing @Nat Struct Mol Biol Oct, 2024
TMEM63B paper by Yugo Miyata et al. is finally out @Nat Struct Mol Biol. Congrats, Yugo!
We identified TMEM63B as a membrane structure-responsive lipid scramblase to control plasma membrane lipid distribution.
Kastuya and Yongchan in Tomo Nishizawa's team @ YCU detemined its open and closed structures.
This article is featured in Research Briefing @Nat Struct Mol Biol.
Amazing collaborative work!
TMEM63B paper @Nat Struct Mol Biol Sep, 2024
The last day as the TMDU. We are going to be a member of the Institute of Science Tokyo from Oct 2024.
Amazing team for 3 years.
Go for the next!
Sep, 2024
Our very recent study of identification of a new type of lipid scramblase to control plasma membrane lipid distribution was accepted and will be published soon!
This is an amazing collaborative study with Tomo Nishizawa team with Katsuya and Yongchan @YCU!!
Coming Soon!!
Sep, 2024
Yugo joined a meeting of Grant-in-Aid for Transformative Research Areas (A) @ Osaka.
He was awarded for Best Presentation.
Congrats!
Sep, 2024
Dr. Masahiro Nagata have joined our team as an assisstant peofessor.
He have been worked on fields of innate immunity and cell death, and will have a project for innate immunity using a genome-wide screen in our lab.
Go for it!
July, 2024
Yusui Ishii and Yu Karibe, TMDU Med School students, have joined our team!
12Apr, 2024
Kats had a senimar @Juntendo U.
Juntendo U Cell Biology seminar 1Apr, 2024
Futaba Imahayashi-san and Momoka Uehara-san, TMDU Med School students, have joined our team!
21Mar, 2024
Nishimura-san, Shiraki-san, and Nagat-san have graduated from Kitasato U! Congrats!
We had a farewell party for Yu Shiraki-san. She did good jobs on a novel lipid scramblase, and will join @Dr. Takuya Matsuo Lab in Kitasato U.
Good luck!
2023
5-6 Oct, 2023
We had the 18th International Symposium of the Institute Network for Biomedical Sciences @MRI TMDU.
We had Dr. Shigekazu Nagata from Osaka U, Dr. Yasunori Saheki from Nanyang Tech U in Singapore, and Dr. Nick Barker from A*STAR in Singapore as keynote speakers.
The 18th International Symposium 1 Oct, 2023
Ayodya de Alwis from Sri Lanka has joined our team as a MEXT scholarship grad school student.
Welcome, Ayodya-san!
3 Aug, 2023
We had the 1st MedChem seminar @TMDU.
The guest speaker was Dr. Feng Shao from Beijing.
Title: Activation of antitumor immunity by bacteria-derived signals: Pyroptosis and Beyond
The seminar was actually fantastic! And, your advice encouraged us very much! Thanks, Feng!
15 Jul, 2023
We joined the 31st Japan Cell Death Meeting @Juntendo U and TMDU.
31st Cell Death Meeting Great talks from many colleagues in Japan, and the keynote lectures was given by Dr. Feng Shao who identified intracellular LPS receptors and Gasdermins.
It was actually amazing! Thanks Dr. Feng!
Dr. Feng Shao 13 Jul, 2023
We had a seminar by Dr. Masahiro Nagata from University of Cologne in Germany.
He has worked and focused on pore-forming proteins in caspase-8 mediated cell death and inflammation in Dr. Manolis Pasparakis Lab. Thanks!
Dr. Manolis Pasparakis Lab 1 Apr, 2023
New team members from Kitasato U have joined our team. Yu Siraki, Megumi Nishimura, and Aya Nagata. Welcome!
北里大学から3名の卒業研究生がteamに加わりました。
6 Jan, 2023
Our recent work has been featured in KAKEN topics.
最近の仕事がKAKENトピックスで紹介されました。
KAKEN Topics
2022
16 Dec, 2022
Moe Nishimoto has joined our team!
技術補佐員として西本萌恵さんがteamに加わりました。
31 Oct, 2022
A protocol to analyze membrane-lipid asymmetry and flippase activity is accepted for publication in STAR Protocols. Congrats, Yugo.
宮田助教の論文がSTAR Protocolsに受理されました。細胞膜外層の膜脂質とflippase activityの検出法のstep-by-step protocolです。
17 Oct, 2022
Our story of flippases and scramblases with Dr. S. Nagata and Dr. J. Suzuki has been described in the most popular text book, “the CELL” 7th edition.
1 Oct, 2022
Chikako Sawada and Xu Xing have joined our team!
秘書の澤田さんと研究生のXu Jingさんがラボのメンバーになりました！ よろしくお願い致します。
22 Sep, 2022
A paper by Yugo is accepted for publication in J Biol Chem. Congrats! Yugo.
Two types of type IV P-type ATPases independently re-establish the asymmetrical
distribution of phosphatidylserine in plasma membranes
宮田助教の論文がJ Biol Chemに受理されました。 ~ホスファチジルセリンの非対称分布の維持に二つのタイプのフリッパーゼが独立して関与する〜
20 Sep, 2022
Our proposal has been accepted by AMED-PRIME (Proteostasis)
AMED-PRIME (Proteostasis)に採択されました
5 Aug, 2022
Our new team member, SULTAN Cheryl Sophia, has been acceped for JSPS PD research fellow. Congrats! Cheryl!
23 Jun, 2022
学術領域変革研究(A) 生体防御における自己認識の「功」と「罪」の計画研究が採択されました
1 Apr, 2022
栗林梨沙さんが技術補佐員としてラボに参加しました
24 Mar, 2022
大阪大学 長田重一教授との共著論文がProc Natl Acad Sci USAに受理されました 落合さん、おめでとうございます！
10 Mar, 2022
本学医学部医学科 2年 蜂巣頌くんがラボに参加しました
14 Feb, 2022
本学医学部医学科 1年 島田康介くんがラボに参加しました
10 Feb, 2022
本学医学部医学科 2年 篠田和さんがラボに参加しました
8 Jan, 2022
大阪大学 長田重一教授との共著論文がProc Natl Acad Sci USAに受理されました 領田さん、おめでとうございます！
