Institute of Integrated Research, Institute of Science Tokyo

Department of Advanced Nanomedical Engineering,
Medical Research Laboratory

Junichi ISHIKAWA

石川 絢一

Junichi ISHIKAWA, M.D., Ph.D.

Project Assistant Professor
E-mail:

Research Keywords

Drug delivery system (DDS), mRNA vaccine, Autoimmune disease

Biography

Education

2015.3  M.D. School of Medicine, Chiba University, Chiba, Japan
2023.3  Ph.D. in Medicine. Graduate School of Medicine, Chiba University, Chiba, Japan (Leading Graduate School at Chiba University)

Research History

2023.4-
2023.9 
Research Fellow, Department of Allergy and Clinical immunology, Graduate School of Medicine, Chiba University, Chiba, Japan
2023.10-
2024.6 
Project Assistant Professor, Department of Allergy and Clinical immunology, Graduate School of Medicine, Chiba University, Chiba, Japan
2024.7-  Project Assistant Professor, Department of Advanced Nanomedical Engineering, Medical Research Laboratory, Institute of Integrated Research, Institute of Science Tokyo (former name Tokyo Medical and Dental University)

Clinical Training

2015.4-
2017.3 
Junior Resident, Tokyo Metropolitan Tama Medical Center, Tokyo, Japan
2017.4-
2018.3 
Senior Resident, Clinical Immunology, Yokohama Rousai Hospital, Kanagawa, Japan
2018.4-
2019.3 
Senior Resident, Internal Medicine, Japanese Red Cross Narita Hospital, Chiba, Japan
2019.4-
2020.3 
Senior Resident, Allergy and Clinical Immunology, Chiba University Hospital, Chiba, Japan
2020.4-
2024.6 
Clinical Fellow, Allergy and Clinical Immunology, Chiba University Hospital, Chiba, Japan

Achievements

Publications

  1. Ishikawa J, Suto A, Abe K, Hayashi Y, Suga K, Tanaka S, Kageyama T, Iwata A, Suzuki K, Suzuki K, Nakajima H. IL-21 is required for the maintenance and pathogenesis of murine Vγ4+ IL-17-producing γδT cells. Front Immunol. 14:1211620. (2023)
  2. Suga K, Suto A, Tanaka S, Sugawara Y, Kageyama T, Ishikawa J, Sanayama Y, Ikeda K, Furuta S, Kagami S, Iwata A, Hirose K, Suzuki K, Ohara O, Nakajima H. TAp63, a methotrexate target in CD4+ T cells, suppresses Foxp3 expression and exacerbates autoimmune arthritis. JCI Insight. 8(10):e164778. (2023)
  3. Ida T, Furuta S, Takayama A, Tamura J, Hayashi Y, Abe K, Kurihara S, Ishikawa J, Iwamoto T, Ikeda K, Suzuki K, Nakajima H. Efficacy and safety of dose escalation of tofacitinib in refractory anti-MDA5 antibody-positive dermatomyositis. RMD Open. 9(1):e002795. (2023)
  4. Hattori K, Tanaka S, Ishikawa J, Yabe Y, Iwamoto T, Furuta S, Ikeda K, Suzuki K, Nakajima H. Visceral disseminated varicella zoster virus infection during non-intensive maintenance therapy in a patient with systemic lupus erythematosus. Mod Rheumatol Case Rep. 7(1):57–59. (2023)
  5. Suzuki K, Suzuki K, Yabe Y, Iida K, Ishikawa J, Makita S, Kageyama T, Iwamoto T, Tanaka S, Yokota M, Iwata A, Suto A, Nakajima H. NF-κB1 Contributes to Imiquimod-Induced Psoriasis-Like Skin Inflammation by Inducing Vγ4+Vδ4+ γδT17 Cells. J Invest Dermatol. 142(6):1639–1649.e5 (2021)
  6. Abe K, Ishikawa Y, Ishikawa J, Fujiwara M, Kita Y. Successful treatment of a patient with refractory immune thrombocytopenic purpura in systemic lupus erythematosus with rituximab. Immunol Med. 42(4):185–188 (2019)
  7. Ishikawa Y, Hattori K, Ishikawa J, Fujiwara M, Kita Y. Refractory Sjögren’s syndrome myelopathy successfully treated with subcutaneous tocilizumab: A case report. Medicine (Baltimore). 98(27):e16285 (2019)
  8. Ishikawa Y, Kasuya T, Ishikawa J, Fujiwara M, Kita Y. A case of developing progressive multifocal leukoencephalopathy while using rituximab and mycophenolate mofetil in refractory systemic lupus erythematosus. Ther Clin Risk Manag. 14:1149–1153. (2018)

Books

  1. Ishikawa J, Suto A, Nakajima H. “The role of γδT17 cells in their differentiation and proliferation, and in the development of autoimmune diseases”. Clinical Immunology and Allergology vol. 81 No.4, Tokyo, KAGAKU-HYORONSHA, 2024, p. 366-372, ISSN:1881-1930

Awards

2024.6 Young Scientist Award, the 16th Chiba Medical Society Award
2023.5 Young Scientist Award, Japanese Society for Interferon and Cytokine Research 2023 Joint Symposium
2022.12 Best Poster Award at the 51st Annal Meeting of the Japanese Society for Immunology
2021.3 Excellent LGS Student Award, Leading Graduate School, Chiba University

Research Fundings

2023-2025 JSPS, KAKENHI, Grant-in-Aid for Young Scientists (PI)

Medical Certification

2015 Japanese National Board of Medicine
2018 Board Certified in Internal Medicine
2022 Board Certified in Rheumatologist
2023 Board Certified in Senior Rheumatologist

Memberships

  • Japanese Society of Internal Medicine
  • Japan College of Rheumatology
  • Japanese Society of Allergology
  • The Japanese Society for Immunology
  • The Japanese Society of Clinical Immunology
  • Japanese Cytokine Society
  • The Japan Society of Drug Delivery System