Department of Developmental and Regenerative Biology

Publications

Nishina's Group : Articles and Reviews (2005-)

2025

• Miki Nishio, Keiko Yamaguchi, Junji Otani, Katsuya Yuguchi, Daisuke Kohno, Tsutomu Sasaki, Tadahiro Kitamura, Masakazu Shinohara, Tomoyoshi Soga, Koichi Kawamura, Atsuo T., Masashi Oshima, Hiroki Hikasa, Minna Woo, Takehiko Sasaki, Hiroshi Nishina, Kazuwa Nakao, Tomohiko Maehama and Akira Suzuki (2025) Mob1 deletion in murine mature adipocytes ameliorates obesity and diabetes. Proc Natl Acad Sci USA accepted
• Noriyuki Azuma, Yuki Yamaguchi, Taku Tanaka, Emiko Matsuzaka, Yuki Saida, Tadashi Yokoi, Hiroshi Handa, Jun Hirayama, Hiroshi Nishina (2025) INTS15,A Subunit of the Integrator Complex, Plays a Key Regulatory Role in Cell Cycle and Differentiation. Genes to Cells
• Noriyuki Azuma, Keiko Tadokoro, Masao Yamada, Masato Nakafuku and Hiroshi Nishina (2025) Sonic hedgehog determines early retinal development and adjusts eyeball architecture. Int. J. Mol. Sci. 26, 496.

2023

• Jing Pu, Satoshi Kofuji, Yoshimi Okamoto-Uchida, Keiko Danzaki, Ruoxing Yu, Akira Suzuki, Satoshi Kitajima and Hiroshi Nishina (2023) Lethal phenotype-based database screening identifies ceramide as a negative regulator of primitive streak formation. Stem Cells 10.1093/stmcls/sxad071, Press release
• Noriyuki Azuma, Tadashi Yokoi, Taku Tanaka, Emiko Matsuzaka, Yuki Saida, Sachiko Nishina, Miho Terao, Shuji Takada, Maki Fukami, Kohji Okamura, Kayoko Maehara, Tokiwa Yamasaki, Jun Hirayama, Hiroshi Nishina, Hiroshi Handa, and Yuki Yamaguchi (2023) Integrator complex subunit 15 controls mRNA splicing and is critical for eye development. Human Molecular Genetics accepted, Press release
• Hajime Tajima Sakurai, Hidefumi Iwashita, Satoko Arakawa, Alifu Yikelamu, Mizuki Kusaba, Satoshi Kofuji, Hiroshi Nishina, Munetaka Ishiyama, Yuichiro Ueno, and Shigeomi Shimizu (2023) Development of small fluorescent probes for the analysis of autophagy kinetics. iScience 26(7): 107218.

2022

• Hirotoshi Soyama, Miki Nishio, Junji Otani, Toshiko Sakuma, Shintaro Takao, Shigeo Hara, Takaaki Masuda, Koshi Mimori, Shinya Toyokuni, John P Lydon, Kazuwa Nakao, Hiroshi Nishina, Takumi Fukumoto, Tomohiko Maehama and Akira Suzuki (2022)　Hippo-TAZ signaling is the master regulator of the onset of triple negative basal-like breast cancers. Proc Natl Acad Sci USA 119(29):e2123134119.
• Caleb Kwame Sinclear, Junichi Maruyama, Shunta Nagashima, Kyoko Arimoto-Matsuzaki, Joshua Agbemefa Kuleape, Hiroaki Iwasa, Hiroshi Nishina, Hata, Yutaka (2022) Protein kinase Cα activation switches YAP1 from TEAD-mediated signaling to p73-mediated signaling. Cancer Science 10.1111/cas.15285
• Takeaki Shibata, Hiroki Kawana, Yuri Nishino, Yoshiko Ito, Hiroyasu Sato, Hirofumi Onishi, Kuniyuki Kano, Asuka Inoue, Yoshitaka Taketomi, Makoto Murakami, Satoshi Kofuji, Hiroshi Nishina, Atsuo Miyazawa, Nozomu Kono1 and Junken Aoki (2022) Abnormal male reproduction and embryonic development induced by downregulation of a phospholipid fatty acid-introducing enzyme Lpgat1 in zebrafish. Scientific Reports 12, 7312.
• Chiyumi Oda, Kenya Kamimura, Osamu Shibata, Shinichi Morita, Yuto Tanaka, Toru Setsu, Hiroyuki Abe, Takeshi Yokoo, Akira Sakamaki, Hiroteru Kamimura, Satoshi Kofuji, Toshifumi Wakai, Hiroshi Nishina, Shuji Terai (2022) HBx and YAP Expression Could Promote Tumor Development and Progression in HBV-related Hepatocellular Carcinoma. Biochem. Biophys. Rep. 32, 101352.
• Sakurako Kobayashi, Nobuhiko Ogasawara, Satoshi Watanabe, Yosuke Yoneyama, Sakura Kirino, Yui Hiraguri, Masami Inoue, Sayaka Nagata, Yoshimi Okamoto-Uchida, Satoshi Kofuji, Hiromichi Shimizu, Go Ito, Tomohiro Mizutani, Shinichi Yamauchi, Yusuke Kinugasa, Yoshihito Kano, Yasuhiro Nemoto, Mamoru Watanabe, Kiichiro Tsuchiya, Hiroshi Nishina, Ryuichi Okamoto, Shiro Yui (2022) Collagen Type I mediated mechnotransduction controls epithelial cell fate conversion during intestinal inflammation. Inflammation and Regeneration 42(1):49.
• Hiroshi Nishina (2022) [review] Physiological and pathological roles of the Hippo-YAP/TAZ signaling pathway in liver formation, homeostasis and tumorigenesis. Cancer Science DOI: 10.1111/cas.15352

2021

• Sachi Sunaga, Satoshi Kofuji and Hiroshi Nishina (2021) YAP drives cell competition by activating choline metabolism. Biochem. Biophys. Res. Commun. 572, 178-184.
• Tadashi Shin, Yuichi Hiraoka, Tokiwa Yamasaki, Jamey D. Marth, Josef M. Penninger, Masami Kanai-Azuma, Kohichi Tanaka, Satoshi Kofuji & Hiroshi Nishina (2021) MKK7-deficiency in mature neurons impairs parental behavior in mice. Genes to Cells 26, 5-17.
• Yikelamu Alifu, Satoshi Kofuji, Sachi Sunaga, Mizuki Kusaba, Jun Hirayama, and Hiroshi Nishina (2021) The light-inducible genes Per2, Cry1a, and Cry2a regulate oxidative status in zebrafish. Biological and Pharmaceutical Bulletin 44, 1160-1165.
• Takako Ooshio, Masahiro Yamamoto, Kiyonaga Fujii, Bing Xin, Kenji Watanabe, Masanori Goto, Yoko Okada, Akira Suzuki, Josef M. Penninger, Hiroshi Nishina, and Yuji Nishikawa (2021) Hepatocyte MKK7 Contributes to Restoration of the Liver Parenchyma Following Injury. Hepatology 73, 2510-2526.
• Shoko Miyata; Noriaki Saku; Saeko Akiyama; Palaksha Kanive Javaregowda; Kenta Ite; Nagisa Takashima; Masashi Toyoda; Kei Yura; Tohru Kimura; Hiroshi Nishina; Atsuko Nakazawa; Mureo Kasahara; Hidenori Nonaka; Tohru Kiyono; Akihiro Umezawa (2021) Puromycin-based purification of cells with high expression of the cytochrome P450 CYP3A4 gene from a patient with drug-induced liver injury (DILI) Stem Cell Research & Therapy DOI : 10.1186/s13287-021-02680-4
• Joshua Agbemefa Kuleape, Shakhawoat Hossain, Caleb Kwame Sinclear, Takanobu Shimizu, Hiroaki Iwasa, Junichi Maruyama, Kyoko Arimoto-Matsuzaki, Hiroshi Nishina, and Yutaka Hata (2021) DNA damage triggers the nuclear accumulation of RASSF6 tumor suppressor protein via CDK9 and BAF53 to regulate p53-target gene transcription. Mol. Cell Biol. DOI: 10.1128/MCB.00310-21
• Keisuke Nakatani, Tomohiko Maehama, Miki Nishio, Junji Otani, Keiko Yamaguchi, Miki Fukumoto, Hiroki Hikasa, Shinji Hagiwara, Hiroshi Nishina, Tak Wah Mak, Teruki Honma, Yasumitsu Kondoh, Hiroyuki Osada, Minoru Yoshida and Akira Suzuki (2021) Alantolactone is a natural product that potently inhibits YAP1/TAZ via promotion of ROS accumulation Cancer Science doi: 10.1111/cas.15079.
• Shunta Nagashima, Junichi Maruyama, Kaori Honda, Yasumitsu Kondoh, Hiroyuki Osada, Makiko Nawa, Ken-ichi Nakahama, Mari Ishigami-Yuasa, Hiroyuki Kagechika, Haruhiko Sugimura, Hiroyuki Iwasa, Kyoko Arimoto-Matsuzaki, Hiroshi Nishina, and Yutaka Hata (2021) CSE1L promotes nuclear accumulation of transcriptional coactivator TAZ and enhances invasiveness of human cancer cells. J. Biol. Chem. 297(1) 100803
• Xinliang Jiang1, Junichi Maruyama1, Hiroaki Iwasa1, Kyoko Arimoto-Matsuzaki, Hiroshi Nishina, Yutaka Hata (2021) Heat shock induces the nuclear accumulation of YAP1 via SRC. Exp Cell Res 399, 112439
• Mayu Morishita, Kyoko Arimoto-Matsuzaki, Masami Kitamura, Kyohei Niimura, Hiroaki Iwasa, Junichi Maruyama, Yuichi Hiraoka, Kohei Yamamoto, Masanobu Kitagawa, Norio Miyamura, Hiroshi Nishina, Yutaka Hata (2021) Characterization of mouse embryonic fibroblasts derived from Rassf6 knockout mice reveals the implication of Rassf6 in the regulation of NF-κB signaling. Genes to Cells accept
• Anti-YAP clone 8G5 antibody (catalog code MASBS2029)

2020

• Erika Ishihara, Yuya Nagaoka, Toshiaki Okuno, Satoshi Kofuji, Mari Ishigami-Yuasa, Hiroyuki Kagechika, Kenya Kamimura, Shuji Terai, Takehiko Yokomizo, Yukihiko Sugimoto, Yasuyuki Fujita, Akira Suzuki and Hiroshi Nishina (2020) Prostaglandin E2 and its receptor EP2 trigger signaling that contributes to YAP-mediated cell competition. Genes to Cells 25, 197-214.
• Hirofumi Omori, Miki Nishio, Muneyuki Masuda, Yosuke Miyachi, Fumihito Ueda, Takafumi Nakano, Kuniaki Sato, Koshi Mimori, Kenichi Taguchi, Hiroki Hikasa, Hiroshi Nishina, Hironori Tashiro, Toru Kiyono, Tak Wah Mak, Kazuwa Nakao, Takashi Nakagawa, Tomohiko Maehama and Akira Suzuki (2020) YAP1 is a Potent Driver of the Onset and Progression of Oral Squamous Cell Carcinoma. Science Advance 6: eaay3324
• Kenya Kamimura, Takeshi Yokoo, Hiroyuki Abe, Norihiro Sakai, Takuro Nagoya, Yuji Kobayashi, Masato Ohtsuka, Hiromi Miura, Akira Sakamaki, Hiroteru Kamimura, Norio Miyamura, Hiroshi Nishina, Shuji Terai (2020) Effect of Diphtheria Toxin-Based Gene Therapy for Hepatocellular. Cancers 12(2), 472.
• Miki Nishio,Yoko To, Tomohiko Maehama, Yukari Aono, Junji Otani, Hiroki Hikasa, Akihiro Kitagawa, Koshi Mimori, Takehiko Sasaki, Hiroshi Nishina, Shinya Toyokuni, John P. Lydon, Nishina, Kazuwa Nakao, Tak Wah Mak, Tohru Kiyono, Hidetaka Katabuchi, Hironori and Akira Suzuki (2020) Endogenous YAP1 activation Drives Immediate Onset of Cervical Carcinoma In Situ in Mice. Cancer Science 111, 3576-3587.
• Takanobu Shimizu, Takeshi Nakamura, Hironori Inaba, Hiroaki Iwasa, Junichi Maruyama, Kyoko Arimoto-Matsuzaki, Takao Nakata, Hiroshi Nishina, Yutaka Hata (2020) The RAS-interacting chaperone UNC119 drives the RASSF6-MDM2-p53 axis and antagonizes RAS-mediated malignant transformation. J. Biol. Chem. 295, 11214-11230.
• Nozomi Hanzawa, Koshi Hashimoto, Xunmei Yuan, Kenichi Kawahori, Kazutaka Tsujimoto, Miho Hamaguchi, Toshiya Tanaka, Yuya Nagaoka, Hiroshi Nishina, Sumiyo Morita, Izuho Hatada, Tetsuya Yamada, and Yoshihiro Ogawa (2020) Targeted DNA demethylation of the Fgf21 promoter by CRISPR/dCas9-mediated epigenome editing. Scientific Reports 10, 5181.
• Manami Kodaka, Kyoko Arimoto-Matsuzaki, Xiaoyin Xu, Zeyu Yang, Fengju Mao, Yue Guo, Junichi Maruyama, Kentaro Nakagawa, Kana Ishii, Chihiro Akazawa, Takuya Oyaizu, Naoki Yamamoto, Mitsuhiro Enomoto, Mari Ishigami-Yuasa, Nozomi Tsuemoto, Shigeru Ito, Hiroyuki Kagechika, Hiroshi Nishina, Yutaka Hata (2020) Characterization of a novel compound that promotes myogenesis via Akt and transcriptional co-activator with PDZ-binding motif (TAZ) in mouse C2C12 cells. PLoS ONE 15(4) e0231265.

2019

• Jun Hirayama1*, Yikelamu Alifu1, Rin Hamabe, Sho Yamaguchi, Jun Tomita, Yusuke Maruyama, Yoichi Asaoka, Ken-ichi Nakahama, Teruya Tamaru, Ken Takamatsu, Nobuhiko Takamatsu, Atsuhiko Hattori, Sachiko Nishina, Noriyuki Azuma, Atsuo Kawahara, Kazuhiko Kume*, Hiroshi Nishina* (2019) The clock components Period2, Cryptochrome1a, and Cryptochrome2a function in establishing light-dependent behavioral rhythms and/or total activity levels in zebrafish. Scientific Reports 9, 196 (*corresponding authors) Press release
• Miki Nishio, Yousuke Miyachi, Junji Otani, Shoji Tane, Hirofumi Omori, Fumihito Ueda, Hideru Togashi, Takehiko Sasaki, Tak Wah Mak, Kazuwa Nakao, Yasuyuki Fujita, Hiroshi Nishina, Tomohiko Maehama and Akira Suzuki (2019) Hippo pathway controls cell adhesion and context-dependent cell competition to influence skin engraftment efficiency. FASEB J doi: 10.1096/fj.201802005R
• Takuro Nagoya, Kenya Kamimura, Ryo Goto, Yoko Shinagawa‐Kobayashi, Yusuke Niwa, Atsushi Kimura, Norihiro Sakai, Masayoshi Ko, Hiroshi Nishina, Shuji Terai (2019) Inhibition of sodium‐glucose cotransporter 2 ameliorated renal injury in a novel medaka model of nonalcoholic steatohepatitis‐related kidney disease. FEBS Open Bio doi: 10.1002/2211-5463.12734
• Ryo Goto, Kenya Kamimura, Yoko Shinagawa-Kobayashi, Norihiro Sakai, Takuro Nagoya, Yusuke Niwa, Masayoshi Ko, Kohei Ogawa, Ryosuke Inoue, Takeshi Yokoo, Akira Sakamaki, Hiroteru Kamimura, Satoshi Abe, Hiroshi Nishina and Shuji Terai (2019) Inhibition of sodium glucose cotransporter 2 (SGLT2) delays liver fibrosis in a medaka model of nonalcoholic steatohepatitis (NASH). FEBS Open Bio doi:10.1002/2211-5463.12598

2018

• Hiroki Goto, Miki Nishio, Yoko To, Tatsuya Oishi, Yosuke Miyachi, Tomohiko Maehama, Hiroshi Nishina, Haruhiko Akiyama, Tak Wah Mak, Yuma Makii, Taku Saito, Akihiro Yasoda, Noriyuki Tsumaki, and Akira Suzuki (2018) Loss of Mob1a/b in mice results in chondrodysplasia due to YAP1/TAZ-TEADs-dependent repression of SOX9. Development 145, dev159244
• Asami Kawasaki, Masayasu Okada, Atsushi Tamada, Shujiro Okuda, Motohiro Nozumi, Yasuyuki Ito, Daiki Kobayashi, Tokiwa Yamasaki, Ryo Yokoyama, Takeshi Shibata, Hiroshi Nishina, Yutaka Yoshida, Yukihiko Fujii, Kosei Takeuchi, and Michihiro Igarashi (2018) Growth cone phosphoproteomics reveals that GAP-43 phosphorylated by JNK is a marker of axon growth and regeneration. iScience 4, 190-203.
• Junichi Maruyama, Kazutoshi Inami, Fumiyoshi Michishita, Xinliang Jiang, Hiroaki Iwasa, Kentaro Nakagawa, Mari Ishigami-Yuasa, Hiroyuki Kagechika, Norio Miyamura, Jun Hirayama, Hiroshi Nishina, Daichi Nogawa, Kouhei Yamamoto, and Yutaka Hata (2018) Novel YAP1 Activator, Identified by Transcription-based Functional Screen, Limits Multiple Myeloma Growth. Molecular Cancer Research 16 (2), 197-211.
• Yoko Shinagawa-Kobayashi, Kenya Kamimura, Ryo Goto, Kohei Ogawa, Ryosuke Inoue, Takeshi Yokoo, Norihiro Sakai, Takuro Nagoya, Akira Sakamaki, Satoshi Abe, Soichi Sugitani, Masahiko Yanagi, Koichi Fujisawa, Yoshizu Nozawa, Naoto Koyama, Hiroshi Nishina, Makoto Furutani-Seiki, Isao Sakaida, Shuji Terai (2018) Effect of histidine on sorafenib-induced vascular damage: Analysis using novel medaka fish model. Biochem. Biophys. Res. Commun. 496, 556-561.
• Ryosuke Inoue, Kenya Kamimura, Takuro Nagoya, Norihiro Sakai, Takeshi Yokoo, Ryo Goto, Kohei Ogawa, Yoko Shinagawa-Kobayashi, Yukari Watanabe-Mori, Akira Sakamaki, Satoshi Abe, Hiroteru Kamimura, Norio Miyamura, Hiroshi Nishina and Shuji Terai (2018) Effect of a Neural Relay on Liver Regeneration in Mice: Activation of Serotonin Release from the Gastrointestinal Tract. FEBS Open Bio 8, 449-460.
• Norio Miyamrua and Hiroshi Nishina (2018) [book] Molecular Mechanisms of Liver Development: Lessons from Animal Models. Stem Cells and Cancer in Hepatology (Yun-Wen Zheng, eds) pp1-20, Academic Press, London.
• Erika Ishihara and Hiroshi Nishina (2018) [commentary] The Hippo-YAP pathway regulates 3D organ formation and homeostasis. Cancers 2018, 10(4), 122.
• Norio Miyamura and Hiroshi Nishina (2018) [review] YAP regulates liver size and function. Cell Cycle, 17:3, 267-268.

2017

• Norio Miyamura, Shoji Hata, Tohru Itoh, Minoru Tanaka, Miki Nishio, Michiko Itoh, Yoshihiro Ogawa, Shuji Terai, Akira Suzuki, Isao Sakaida, Atsushi Miyajima and Hiroshi Nishina (2017) YAP determines the cell fate of injured mouse hepatocytes in vivo. Nature Communications 8, 16017.
• Tokiwa Yamasaki¹, Norie Deki-Arima¹, Asahito Kaneko, Norio Miyamura, Mamiko Iwatsuki, Masato Matsuoka, Noriko Fujimori-Tonou, Yoshimi Okamoto-Uchida, Jun Hirayama, Jamey D. Marth, Yuji Yamanashi, Hiroshi Kawasaki, Koji Yamanaka, Josef M. Penninger, Shigenobu Shibata and Hiroshi Nishina (2017) Age-dependent motor dysfunction due to neuron-specific disruption of stress-activated protein kinase MKK7. Scientific Reports 7, 7348. (¹Contributed equally) Press release
• Tatsuyuki Matsudaira, Kojiro Mukai, Taishin Noguchi, Junya Hasegawa, Tomohisa Hatta, Shun-ichiro Iemura, Tohru Natsume, Norio Miyamura, Hiroshi Nishina, Jun Nakayama, Kentaro Semba, Takuya Tomita, Shigeo Murata, Hiroyuki Arai and Tomohiko Taguchi (2017) Endosomal phosphatdylserine is critical for the YAP signalling pathway in proliferating cells. Nature Communications 8, 1246.
• Kohei Otsubo, Hiroki Goto, Miki Nishio, Koichi Kawamura, Shigehisa Yanagi, Wataru Nishie, Takehiko Sasaki, T, Tomohiko Maehama, Hiroshi Nishina, Koshi Mimori, Toru Nakano, Hiroshi Shimizu, Tak W. Mak, Kazuwa Nakao, Yoichi Nakanishi and Akira Suzuki (2017) MOB1-YAP1/TAZ-NKX2.1 axis controls bronchioalveolar cell differentiation, adhesion, and tumor formation. Oncogene 36, 4201-4211.
• Seiichiro Mori, Takamasa Takeuchi, Yoshiyuki Ishii, Takashi Yugawa, Tohru Kiyono, Hiroshi Nishina and Iwao Kukimoto (2017) Human Papillomavirus 16 E6 Up-regulates APOBEC3B via the TEAD Transcription Factor. J Virology e02413-16
• Jun Negishi, Yuka Omori, Mami Shindo, Hayate Takanashi, Shiori Musha, Suminori Nagayama, Jun Hirayama, Hiroshi Nishina, Takashi Nakakura, Chihiro Mogi, Koichi Sato, Fumikazu Okajima, Yuta, Mochimaru and Hideaki Tomura (2017) Manganese and cobalt activate zebrafish ovarian cancer G-protein-coupled receptor 1 but not GPR4. Journal of Receptors and Signal Transduction 37, 401-408.
• Yoichi Asaoka, Hiroshi Nishina and Makoto Furutani-Seiki (2017) [review] YAP is essential for 3D organogenesis withstanding gravity. Develop. Growth Differ 59, 52-58.

2016

• Yoshimi Okamoto-Uchida¹, Ruoxing Yu¹, Norio Miyamura, Norie Arima, Mari Ishigami-Yuasa, Hiroyuki Kagechika, Suguru Yoshida, Takamitsu Hosoya, Makiko Nawa, Takeshi Kasama, Yoichi Asaoka, Reiner Wimmer Alois, Ulrich Elling, Josef M. Penninger, Sachiko Nishina, Noriyuki Azuma and Hiroshi Nishina (2016) The mevalonate pathway regulates primitive streak formation via protein farnesylation. Scientific Reports 6, 37697. (¹Contributed equally)
• Takanori Chiba¹, Erika Ishihara¹, Norio Miyamura, Rika Narumi, Mihoko Kajita, Yasuyuki Fujita, Akira Suzuki, Yoshihiro Ogawa and Hiroshi Nishina (2016) Active form of YAP expressing MDCK cells are extruded apically depending on neighboring cells status. Scientific Reports 6, 28383. Press release
• Yoichi Asaoka, Yoko Nagai, Misako Namae, Makoto Furutani-Seiki and Hiroshi Nishina (2016) SLC7 family transporters control the establishment of left-right asymmetry during organogenesis in medaka by activating mTOR signaling. Biochem. Biophys. Res. Commun. 474, 146-153.
• Miki Nishio, Keishi Sugimachi, Hiroki Goto, Jia Wang, Takumi Morikawa, Yosuke Miyachi , Yusuke Takano, Hiroki Hikasa, Tohru Itoh, Satoshi O Suzuki, Hiroki Kurihara, Shinichi Aishima, Andrew Leask, Takehiko Sasaki, Toru Nakano, Hiroshi Nishina, Yuji Nishikawa, Yoshitaka Sekido, Kazuwa Nakao, Kazuo Shin-ya, Koshi Mimori and Akira Suzuki (2016) Dysregulated YAP1/TAZ and TGFβ signaling mediate hepatocarcinogenesis in Mob1a/1b-deficient mice. Proc. Natl. Acad. Sci. USA 113, E71-E80.
• Yusuke Nasu, Yoichi Asaoka, Misako Namae, Hiroshi Nishina, Hideaki Yoshimura and Takeaki Ozawa (2016) Genetically Encoded Fluorescent Probe for Imaging Apoptosis in vivo with Spontaneous GFP Complementation. Analytical Chemistry 88, 838-844.
• Shunta Nagashima, Junichi Maruyama, Shodai Kawano, Hiroaki Iwasa, Kentaro Nakagawa, Mari Ishigami-Yuasa, Hiroyuki Kagechika, Hiroshi Nishina and Yutaka Hata (2016) Validation of chemical compound library screening for transcriptional co-activator with PDZ-binding motif inhibitors using GFP-fused transcriptional co-activator with PDZ-binding motif. Cancer Science 107, 791-802.
• Koichi Fujisawa, Shuji Terai, Taro Takami, Naoki Yamamoto, Takahiro Yamasaki, Toshihiko Matsumoto, Kazuhito Yamaguchi, Yuji Owada, Hiroshi Nishina, Takafumi Noma and Isao Sakaida (2016) Modulation of anti-cancer drug sensitivity through the regulation of mitochondrial activity by adenylate kinase 4. J. Exp. Clin. Cancer Res. 16, 35 (1), 48.

2015

• Sean Porazinski¹, Huijia Wang¹, Yoichi Asaoka¹, Martin Behrndt¹, Tatsuo Miyamoto¹, Hitoshi Morita, Shoji Hata, Takashi Sasaki, S.F. Gabby Krens, Yumi Osada, Satoshi Asaka, Akihiro Momoi, Sarah Linton, Joel B. Miesfeld, Brian A. Link, Takeshi Senga, Atahualpa Castillo-Morales, Araxi O. Urrutia, Nobuyoshi Shimizu, Hideaki Nagase, Shinya Matsuura, Stefan Bagby, Hisato Kondoh, Hiroshi Nishina^*, Carl-Philipp Heisenberg^* and Makoto Furutani-Seiki^* (2015) YAP is essential for tissue tension to ensure vertebrate 3D body shape. Nature 521, 217-221 (^*Corresponding authors) Press release
• Ruoxing Yu, Norio Miyamura, Yoshimi Okamoto-Uchida, Norie Arima, Mari Ishigami-Yuasa, Hiroyuki Kagechika and Hiroshi Nishina (2015) A Modified Murine Embryonic Stem Cell Test for Evaluating the Teratogenic Effects of Drugs on Early Embryogenesis. PLoS ONE 10 e0145286
• Koichi Fujisawa, Shuji Terai, Toshihiko Matsumoto, Taro Takami, Naoki Yamamoto, Hiroshi Nishina, Makoto Furutani-Seiki and Isao Sakaida (2015) Evidence for a Role of the Transcriptional Regulator Maid in Tumorigenesis and Aging. PLoS ONE 10 e0129950
• Shoudai Kawano, Junichi Maruyama, Shunta Nagashima, Kazutoshi Inami, Wenzhe Qiu, Hiroaki Iwasa, Kentaro Nakagawa, Mari Ishigami-Yuasa, Hiroyuki Kagechika, Hiroshi Nishina, Yutaka Hata (2015) A cell-based screening for TAZ activators identifies ethacridine, a widely used antiseptic and abortifacient, as a compound that promotes dephosphorylation of TAZ and inhibits adipogenesis in C3H10T1/2 cells. J. Biochem. 158, 413-423.
• Yuta Motimaru, Morio Azuma, Natsuki Oshima, Yuta Ichijo, Kazuhiro Satou, Kouhei Matsuda, Yoichi Asaoka, Hiroshi Nishina, Takashi Nakakura, Chihiro Mogi, Koichi Sato, Fumikazu Okajima and Hideaki Tomura (2015) Extracellular acidification activates ovarian cancer G-protein-coupled receptor 1 and GPR4 homologs of zebrafish. Biochem. Biophys. Res. Commun. 457, 493-499.

2014

• Yoichi Asaoka^*, Shoji Hata, Misako Namae, Makoto Furutani-Seiki and Hiroshi Nishina^* (2014) The Hippo pathway controls a switch between retinal progenitor cell proliferation and photoreceptor cell differentiation in zebrafish. PLoS ONE 9, e97365.
• Tadanori Shimomura, Norio Miyamura, Shoji Hata, Ryota Miura, Jun Hirayama^* and Hiroshi Nishina^* (2014) The PDZ-binding motif of Yes-associated protein is required for its co-activation of TEAD-mediated CTGF transcription and oncogenic cell transforming activity. Biochem. Biophys. Res. Commun. 443, 917-923.
• Zeyu Yang, Kentaro Nakagawa, Aradhan Sarkar, Junichi, Maruyama, Hiroaki Iwasa, Yijun Bao, Mari Ishigami-Yuasa, Shigeru Ito, Hiroyuki Kagechika, Shoji Hata, Hiroshi Nishina, Shinya Abe, Masanobu Kitagawa, Yutaka Hata (2014) Screening with a novel cell-based assay for TAZ activators identifies a compound that enhances myogenesis in C2C12 cells and facilitates muscle repair in the muscle injury model. Mol. Cell. Biol. 34, 1607-1621.
• Keita Nakanaga, kotaro Hama, Kuniyuki Kano, Takanoa Sato, Hiroshi Yukiura, Asuka Inoue, Daisuke Saigusa, Hidetoshi Tokuyama, Yoshihisa Tomioka, Hiroshi Nishina, Atsuo Kawahara and Junken Aoki (2014) Overexpression of autotaxin, a lysophosphatidic acid-producing enzyme, enhances cardia bifida induced by hypo-sphingosine-1- phosphate signaling in zebrafish embryo. J. Biochem. 155, 235-241.
• Shuji Terai, Taro Takami, Naoki Yamamoto, Koichi Fujisawa, Tsuyoshi Ishikawa, Yohei Urata, Haruko Tanimoto, Takuya Iwamoto, Yuko Mizunaga, Takashi Matsuda, Takashi Oono, Miho Marumoto, Guzel Burganova, Luiz Fernando Quintanilha, Isao Hidaka, Yoshio Marumoto, Issei Saeki, Koichi Uchida, Takahiro Yamasaki, Kenji Tani, Yasuho Taura, Yasuhiko Fujii, Hiroshi Nishina, Kiwamu Okita, and Isao Sakaida (2014) [review] Status and prospects of liver cirrhosis treatment by using bone marrow-derived cells and mesenchymal cells. Tissue Engineering Part B: Reviews 20, 1-5.

2013

• Yoichi Asaoka, Shuji Terai, Isao Sakaida and Hiroshi Nishina (2013) [review] The expanding role of fish models in understanding non-alcoholic fatty liver disease (NAFLD). Disease Models & Mechanisms 6, 905-914.
• Norie Arima¹, Yoshimi Uchida¹, Ruoxing Yu, Koh Nakayama and Hiroshi Nishina (2013) Acetylcholine Receptors Regulate Gene Expression that Is Essential for Primitive Streak Formation in Murine Embryoid Bodies. Biochem. Biophys. Res. Commun. 435, 447-453
• Menno J. Oudhoff, Spencer A. Freeman, Amber L. Couzens, Frann Antignano, Ekaterina Kuznetsova, Paul H. Min, Jeffrey P. Northrop, Bernhard Lehnertz, Dalia Barsyte-Lovejoy, Masoud Vedadi, Cheryl H. Arrowsmith, Hiroshi Nishina, Michael R. Gold, Fabio M.V. Rossi, Anne-Claude Gingras, and Colby Zaph (2013) Control of the Hippo pathway by Set7-dependent methylation of Yap. Dev. Cell 26, 188-194.

2012

• Shoji Hata, Jun Hirayama, Hiroaki Kajiho, Kentaro Nakagawa, Yutaka Hata, Toshiaki Katada, Makoto Furutani-Seiki and Hiroshi Nishina (2012) A novel acetylation cycle of the transcription co-activator Yes-associated protein that is downstream of the Hippo pathway is triggered in response to SN2 alkylating agents. J. Biol. Chem. 287, 22089-22098.
• Yoshimi Uchida, Tomomi Osaki, Tokiwa Yamasaki, Tadanori Shimomura, Shoji Hata, Kazumasa Horikawa, Shigenobu Shibata, Takeshi Todo, Jun Hirayama and Hiroshi Nishina (2012) Involvement of the Stress Kinase Mitogen-activated Protein Kinase Kinase 7 in the Regulation of the Mammalian Circadian Clock. J. Biol. Chem. 287, 8318-8326.
• Yoshimi Uchida, Tadanori Shimomura, Jun Hirayama and Hiroshi Nishina (2012) Light, reactive oxygen species, and magnetic fields activate ERK/MAPK signaling pathway in cultured zebrafish cells. Appl. Magn. Reson. 42, 69-77.
• Miki Nishio, Koichi Hamada, Kohichi Kawahara, Masato Sasaki, Fumihito Noguchi, Shuhei Chiba, Kensaku Mizuno, Satoshi O. Suzuki, Youyi Dong, Masaaki Tokuda, Takumi Morikawa, Hiroki Hikasa, Jonathan Eggenschwiler, Norikazu Yabuta, Hiroshi Nojima, Kentaro Nakagawa, Yutaka Hata, Hiroshi Nishina, Koshi Mimori, Masaki Mori, Takehiko Sasaki, Tak W. Mak, Toru Nakano, Satoshi Itami, and Akira Suzuki (2012) Cancer Susceptibility and embryonic lethality in Mob1A/1B double mutant mice. J. Clin. Invest. 122(12):4505-4518.
• Tadashi Yokoi, Yuko Seko, Tae Yokoi, Hatsune Makino, Shin Hatou, Masakazu Yamada, Tohru Kiyono, Akihiro Umezawa, Hiroshi Nishina, Noriyuki Azuma (2012) Establishment of Functioning Human Corneal Endothelial Cell Line with High Growth Potential. PLoS ONE 7(1):e29677
• Ken Okada, Akihide Kamiya, Keiichi Ito, Ayaka Yanagida, Hidenori Ito, Hiroki Kondou, Hiroshi Nishina and Hiromitsu Nakauchi (2012) Prospective isolation and characterization of bipotent progenitor cells in early mouse liver development. Stem Cells and Development 21, 1124-1133.
• Yuko Mizunaga, Shuji Terai, Naoki Yamamoto, Koichi Uchida, Takahiro Yamasaki, Hiroshi Nishina, Yusuke Fujita, Koh Shinoda, Yoshihiki Hamamoto and Isao Sakaida (2012) Granulocyte colony-stimulating factor and interleukin-1β are important cytokines in repair of the cirrhotic liver after bone marrow cell infusion: comparison of humans and model mice. Cell Transplantation 21, 2363-2375.
• Takuya Iwamoto, Shuji Terai, Yuko Mizunaga, Naoki Yamamoto, Kaoru Omori1, Koichi Uchida, Takahiro Yamasaki,Yasuhiko Fujii, Hiroshi Nishina, and Isao Sakaida (2012) Splenectomy enhances the anti-fibrotic effect of bone marrow cell infusion and improves liver function in cirrhotic mice and patients J. Gastroenterol. 47, 300-312.
• Toshiyuki Oishi, Shuji Terai, Shinya Kuwashiro, Koichi Fujisawa, Toshihiko Matsumoto , Hiroshi Nishina and Isao Sakaida (2012) Ezetimibe reduces fatty acid quantity in liver and decreased inflammatory cell infiltration and improved NASH in medaka model. Biochem. Biophys. Res. Commun. 422, 22-27.
• Shoji Hata and Hiroshi Nishina (2012) [Letters to the Editor] Reply to Sun et al.: Targeting YAP acetylation in cancer. J. Biol. Chem. 287, 35443.
• Tokiwa Yamasaki, Hiroshi Kawasaki and Hiroshi Nishina (2012) [review] Diverse roles of JNK and MKK pathways in the brain. J. Signal Trans. 2012: 459265.
• Hiroshi Nishina (2012) [commentary] hDlk-1: A cell surface marker common to normal hepatic stem/progenitor cells and carcinomas. J. Biochem. 152, 121-123.

2011

• Tokiwa Yamasaki, Hiroshi Kawasaki^*, Satoko Arakawa, Kimiko Shimizu, Shigeomi Shimizu, Orly Reiner, Hideyuki Okano, Sachiko Nishina, Noriyuki Azuma, Josef M. Penninger, Toshiaki Katada and Hiroshi Nishina^* (2011) Stress-activated protein kinase MKK7 regulates axon elongation in the developing cerebral cortex. J. Neurosci. 31, 16872-16883.
• Norio Miyamura¹, Takashi Nakamura¹, Naoko Goto-Inoue, Nobuhiro Zaima, Takahiro Hayasaka, Tokiwa Yamasaki, Shuji Terai, Isao Sakaida, Mitsutoshi Setou and Hiroshi Nishina (2011) Imaging mass spectrometry reveals characteristic changes in triglyceride and phospholipid species in regenerating mouse liver. Biochem. Biophys. Res. Commun. 408, 120-125.
• Tomomi Osaki, Yoshimi Uchida, Jun Hirayama, and Hiroshi Nishina (2011) Diphenyleneiodonium chloride, an inhibitor of NADPH oxidase, suppresses light-dependent induction of clock and DNA repair genes in zebrafish. Biol. Pharm. Bull. 34, 1343-1347.
• Shinya Takahashi, Arisa Ebihara, Hiroaki Kajiho, Kenji Kontani, Hiroshi Nishina and Toshiaki Katada (2011) RASSF7 negatively regulates pro-apoptotic JNK signaling by inhibiting the activity of phospholylated-MKK7. Cell Death Differ. 18, 645-655.
• Shinya Takahashi, Kyoko Sakurai, Arisa Ebihara, Hiroaki Kajiho, Kota Saito, Kenji Kontani, Hiroshi Nishina and Toshiaki Katada (2011) RhoA activation participates in rearrangement of processing bodies and release of nucleated AU-rich mRNAs. Nucleic Acids Res. 39, 3446-3457.
• Hiroshi Yukiura, Kotaro Hama, Keita Nakanaga, Masayuki Tanaka, Yoichi Asaoka, Shinichi Okudaira, Naoaki Arima, Asuka Inoue, Takafumi Hashimoto, Hiroyuki Arai, Atsuo Kawahara, Hiroshi Nishina, and Junken Aoki (2011) Autotaxin regulates vascular development via multiple lysophosphatidic acid (LPA) receptors in zebrafish. J. Biol. Chem. 286, 43972-43983.
• Takuro Hisanaga, Shuji Terai, Takuya Iwamoto, Taro Takami, Naoki Yamamoto, Tomoaki Murata, Toshifumi Matsuyama, Hiroshi Nishina and Isao Sakaida (2011) TNFR1 mediated signaling is important to induce the improvement of liver fibrosis by bone marrow cell infusion. Cell Tissue Res. 346, 79-88.
• Shinya Kuwashiro, Shuji Terai, Toshiyuki Oishi, Fujisawa Koichi, Toshihiko Matsumoto, Hiroshi Nishina and Isao Sakaida (2011) Telmisartan improved nonalcoholic steatohepatitis in medaka (Oryzias latipes) by reducing macrophage infiltration and fat accumulation. Cell Tissue Res.344, 125-134.
• Yijun Bao, Kentaro Nakagawa, Zeyu Yang, Mitsunobu Ikeda, KanchanamalaWithanage, Mari Ishigami-Yuasa, Yukiko Okuno, Shoji Hata, Hiroshi Nishina and Yutaka Hata (2011) A cell-based assay to screen stimulators of the Hippo pathway reveals the inhibitory effect of dobutamine on the YAP-dependent gene transcription. J. Biochem. 150, 199-208.

2010

• Takahiro Negishi, Yoko Nagai, Yoichi Asaoka, Mami Ohno, Misako Namae, Hiroshi Mitani, Takashi Sasaki, Nobuyoshi Shimizu, Shuji Terai, Isao Sakaida, Hisato Kondoh, Toshiaki Katada, Makoto Furutani-Seiki^* and Hiroshi Nishina^* (2010) Retinoic acid signaling positively regulates liver specification by inducing wnt2bb gene expression in medaka. Hepatology 51, 1037-1045. ＜NBRP Medaka＞
• Jinzhan Wu¹, Junko Kubota¹, Jun Hirayama¹, Yoko Nagai, Sachiko Nishina, Tadashi Yokoi, Yoichi Asaoka, Jungwon Seo, Nao Shimizu, Hiroaki Kajiho, Takashi Watanabe, Noriyuki Azuma, Toshiaki Katada and Hiroshi Nishina (2010) p38 Mitogen-Activated Protein Kinase Controls a Switch between Cardiomyocyte and Neuronal Commitment of Murine Embryonic Stem Cells by Activating Myocyte Enhancer Factor 2C-Dependent Bone Morphogenetic Protein 2 Transcription. Stem Cells and Development 19, 1723-1734.
• Jungwon Seo¹, Yoichi Asaoka^1*, Yoko Nagai, Jun Hirayama, Tokiwa Yamasaki, Misako Namae, Shinya Ohata, Nao Shimizu, Takahiro Negishi, Daiju Kitagawa, Hisato Kondoh, Makoto Furutani-Seiki, Josef M. Penninger, Toshiaki Katada and Hiroshi Nishina^* (2010) Negative regulation of wnt11 expression by Jnk signaling during zebrafish gastrulation J. Cell. Biochem. 110, 1022-1037. ZFIN publication
• Kentaro Nakagawa¹, Misato Sugahara¹, Tokiwa Yamasaki¹, Hiroaki Kajiho, Shinya Takahashi, Jun Hirayama, Yasuhiro Minami, Yasutaka Ohta, Toshio Watanabe, Yutaka Hata, Toshiaki Katada and Hiroshi Nishina (2010) Filamin Associates with Stress Signaling Kinases MKK7 and MKK4 and Regulates JNK Activation. Biochem. J. 427, 237-245.
• Yoko Nagai¹, Yoichi Asaoka¹, Misako Namae, Kota Saito, Haruka Momose, Hiroshi Mitani, Makoto Furutani-Seiki, Toshiaki Katada and Hiroshi Nishina (2010) The LIM protein Ajuba is required for ciliogenesis and left-right axis determination in medaka. Biochem. Biophys. Res. Commun. 396, 887-893.
• Yoichi Asaoka and Hiroshi Nishina (2010) [review] Diverse Physiological Functions of MKK4 and MKK7 during Early Embryogenesis. J. Biochem. 148: 393-401.
• Yoshimi Uchida, Jun Hirayama and Hiroshi Nishina (2010) [review] A common origin: signaling similarities in the regulation of the circadian clock and DNA damage responses. Biol. Pharm. Bull. 33, 535-544. Cover of the issue
• Shuhei Tanemura, Tokiwa Yamasaki, Toshiaki Katada and Hiroshi Nishina (2010) [review] Utility and limitations of SP600125, an inhibitor of stress- responsive c-Jun N-terminal kinase. Curr. Enzym. Inhib. 6, 26-33.
• G. Gregory Neely, Keiji Kuba, Anthony Cammarato, Kazuya Isobe, Sabine Amann, Liyong Zhang, Mitsushige Murata, Lisa Elmén, Vaijayanti Gupta, Suchir Arora, Rinku Sarangi, Debasis Dan, Susumu Fujisawa, Takako Usami, Cui-ping Xia, Alex C. Keene, Nakissa N. Alayari, Hiroyuki Yamakawa, Ulrich Elling, Christian Berger, Maria Novatchkova, Rubina Koglgruber, Keiichi Fukuda, Hiroshi Nishina, Mitsuaki Isobe, J. Andrew Pospisilik, Yumiko Imai, Arne Pfeufer, Andrew A. Hicks, Peter P. Pramstaller, Sai Subramaniam, Akinori Kimura, Karen Ocorr, Rolf Bodmer and Josef M. Penninger (2010) A Global In VivoDrosophila RNAi Screen Identifies NOT3 as a Conserved Regulator of Heart Function. Cell 141, 142-153. Cover of the issue
• Toshihiko Matsumoto, Shuji Terai, Toshiyuki Oishi, Shinya Kuwashiro, Koichi Fujisawa, Naoki Yamamoto, Yusuke Fujita, Yoshihiko Hamamoto, Makoto Furutani-Seiki, Hiroshi Nishina and Isao Sakaida (2010) Medaka as a Novel and Accurate Model for Human Nonalcoholic Steatohepatitis. Disease Models & Mechanisms 3, 431-440. Press release, Cover of the issue, Faculty of 1000 Medicine
• Ryuichi Mashima, Kazuho Honda, Yi Yang, Yohei Morita, Akane Inoue, Sumimasa Arimura, Hiroshi Nishina, Hideo Ema, Hiromitsu Nakauchi, Brian Seed, Hideaki Oda and Yuji Yamanashi (2010) Mice lacking Dok-1, Dok-2, and Dok-3 succumb to aggressive histiocytic sarcoma. Laboratory Investigation 90, 1357-1364.
• Shigeomi Shimizu, Akimitsu Konishi, Yuya Nishida, Takeshi Mizuta, Hiroshi Nishina, Akitsugu Yamamoto and Yoshihide Tsujimoto (2010) Involvement of JNK in the regulation of autophagic cell death. Oncogene 29, 2070-2082.
• Masahiko Tanaka, Hideyuki Hara, Hiroshi Nishina, Kentaro Hanada, Kenichi Hagiwara and Tomohiko Maehama (2010) An improved method for cell-to-cell transmission of infectious prion. Biochem. Biophys. Res. Commun. 397, 505-508.

2009

• Jun Hirayama¹, Norio Miyamura¹, Yoshimi Uchida, Yoichi Asaoka, Reiko Honda, Kenji Sawanobori, Takeshi Todo, Takuro Yamamoto, Paolo Sassone-Corsi and Hiroshi Nishina (2009) Common light signaling pathways controlling DNA repair and circadian clock entrainment. Cell Cycle 8, 2794-2801.
• Shuhei Tanemura, Haruka Momose, Nao Shimizu, Daiju Kitagawa, Jungwon Seo, Tokiwa Yamasaki, Kentaro Nakagawa, Hiroaki Kajiho, Josef M. Penninger, Toshiaki Katada and Hiroshi Nishina (2009) Blockage by SP600125 of Fce Receptor-induced degranulation and cytokine gene expression in mast cells is mediated through inhibition of phosphatidylinositol 3-kinase signaling pathway. J. Biochem. 145, 345-354. Cover of the issue.
• Ryota Saito, Tokiwa Yamasaki, Yoko Nagai, Jinzhan Wu, Hiroaki Kajiho, Tadashi Yokoi, Eiichiro Noda, Sachiko Nishina, Hitoshi Niwa, Noriyuki Azuma, Toshiaki Katada and Hiroshi Nishina (2009) CrxOS Maintains Self-Renewal Capacity of Murine Embryonic Stem Cells. Biochem. Biophys. Res. Commun. 390, 1129-1135
• Shinya Ohata, Makiko Nawa, Takeshi Kasama, Tokiwa Yamasaki, Kenji Sawanobori, Shoji Hata, Takashi Nakamura, Yoichi Asaoka, Toshio Watanabe, Hitoshi Okamoto, Takahiko Hara, Shuji Terai, Isao Sakaida, Toshiaki Katada and Hiroshi Nishina (2009) Hematopoiesis-dependent expression of CD44 in murine hepatic progenitor cells. Biochem. Biophys. Res. Commun. 379, 817-823.
• Norio Miyamura¹, Jun Hirayama¹, Kenji Sawanobori, Teruya Tamaru, Yoichi Asaoka, Reiko Honda, Takuro Yamamoto, Hatsume Uno, Ken Takamatsu and Hiroshi Nishina (2009) CLOCK:BMAL-independent circadian oscillation of zebrafish Cryptochrome1a gene. Biol. Pharm. Bull. 32, 1183-1187.
• Nao Shimizu, Hajime Watanabe, Junko Kubota, Jinzhan Wu, Ryota Saito, Tadashi Yokoi, Takumi Era, Takeshi Iwatsubo, Takashi Watanabe, Sachiko Nishina, Noriyuki Azuma^*, Toshiaki Katada and Hiroshi Nishina^* (2009) Pax6-5a Promotes Neuronal Differentiation of Murine Embryonic Stem Cells. Biol. Pharm. Bull. 32, 999-1003. Cover of the issue.
• Yoshifumi Matsumoto, Hiroki Oota, Yoichi Asaoka, Hiroshi Nishina, Koji Watanabe, Janusz M Bujnicki, Shoji Oda, Shoji Kawamura and Hiroshi Mitani (2009) Medaka: a promising model animal for comparative population genomics. BMC Research Notes 2, 88.
• Takashi Nakamura and Hiroshi Nishina (2009) [review] Liver development: lessons from knockout mice and mutant fish. Hepatol. Res. 39, 633-644.

2008

• Shinya Takahashi, Yasuhiro Araki, Yuriko Ohya, Takeshi Sakuno, Shin-ichi Hoshino, Kenji Kontani, Hiroshi Nishina and Toshiaki Katada (2008) Upf1 potentially serves as a RING-related E3 ubiquitin ligase via its association with Upf3 in yeast. RNA 14, 1950-1958.
• Tomohiko Maehama, Masahiko Tanaka, Hiroshi Nishina, Makoto Murakami, Yasunori Kanaho and Kentaro Hanada (2008) RalA functions as an indispensable signal mediator for nutrient sensing system. J. Biol. Chem. 283, 35053-35059.
• Wada T, Stepniak E, Hui L, Leibbrandt A, Katada T, Nishina H, Wagner EF and Penninger JM. (2008) Antagonistic control of cell fates by JNK and p38-MAPK signaling. Cell Death Differ. 15, 89-93.
• Shizue Ohsawa, Tomomi Watanabe, Toshiaki Katada, Hiroshi Nishina and Masayuki Miura (2008) Novel antibody to human BASP1 labels apoptotic cells post-caspase activation. Biochem. Biophys. Res. Commun. 371, 639-643.
• Yoshio Marumoto, Shuji Terai, Yohei Urata, Toshihiko Matsumoto, Yuko Mizunaga, Naoki Yamamoto, Haiyan Jin, Koichi Fujisawa, Tomoaki Murata, Koh Shinoda, Hiroshi Nishina and Isao Sakaida (2008). Continuous high expression of XBP1 and GRP78 is important for the survival of bone marrow cells in CCl4-treated cirrhotic liver. Biochem. Biophys. Res. Commun. 367, 546-552.

2007

• Seiji Ura, Hiroshi Nishina^*, Yukiko Gotoh and Toshiaki Katada (2007) Activation of the JNK patyway by MST1 is essential and sufficient for the induction of chromatin condensation during apoptosis. Mol. Cell. Biol. 27, 5514-5522.
• Nakamura, T., Imai, Y., Matsumoto, T., Sato, S., Takeuchi, K., Igarashi, K., Harada, Y., Azuma, Y., Krust, A., Yamamoto, Y., Nishina, H., Takeda, S., Takayanagi, H., Metzger, D., Kanno, J., Takaoka, K., Martin, TJ., Chambon, P. and Kato, S. (2007) Estrogen prevents bone loss via estrogen receptor alpha and induction of Fas ligand in osteoclasts. Cell 130, 811-823.
• Tsuyoshi Ishikawa, Shuji Terai, Yohei Urata, Yoshio Marumoto, Koji Aoyama, Tomoaki Murata, Yuko Mizunaga, Naoki Yamamoto, Hiroshi Nishina, Koh Shinoda and Isao Sakaida (2007) Administration of. Administration of fibroblast growth factor 2 in combination with bone marrow transplantation synergistically improves carbon tetrachloride-induced liver fibrosis in mice. Cell Tissue Res. 327, 463-470.
• Shoji Hata, Misako Namae and Hiroshi Nishina (2007) [review] Liver development and regeneration: from laboratory study to clinical therapy. Develop. Growth Differ. 49, 163-170. Cover of the issue.

2006

• Daiju Kitagawa, Hiroaki Kajiho, Takahiro Negishi, Seiji Ura, Tomomi Watanabe, Teiji Wada, Hidenori Ichijo, Toshiaki Katada and Hiroshi Nishina (2006) Release of RASSF1C from the nucleus by DAXX degradation links DNA damage and SAPK/JNK activation. EMBO J. 25, 3286-3297.
• Yuichiro Yokoyama, Shuji Terai, Tsuyoshi Ishikawa, Koji Aoyama, Yohei Urata, Yoshio Marumoto, Toshihiko Matsumoto, Hiroshi Nishina, Kazuyuki Nakamura, Kiwamu Okita and Isao Sakaida (2006) Proteomic analysis of serum marker proteins in recipient mice with liver cirrhosis after bone marrow cell transplantation. Proteomics 6, 2564-2570.
• Tsuyoshi Ishikawa, Shuji Terai, Yohei Urata, Yoshio Marumoto, Koji Aoyama, Isao Sakaida, Tomoaki Murata, Hiroshi Nishina, Koh Shinoda, Shunji Uchimura, Yoshihiko Hamamoto and Kiwamu Okita (2006) Fibroblast growth factor 2 facilitates the differentiation of transplanted bone marrow cells into hepatocytes. Cell Tissue Res. 323, 221-231.
• Wada T, Nakashima T, Nishina H and Penninger JM (2006) [review] RANK-RANKL signaling in osteoclastogenesis. Trends Mol Med. 12: 17-25.

2005

• Masataka Asagiri, Kojiro Sato, Takako Usami, Sae Ochi, Hiroshi Nishina, Hiroki Yoshida, Ikuo Morita, Erwin F. Wagner, Tak W. Mak, Edgar Serfling, and Hiroshi Takayanagi (2005) Autoamplification of NFATc1 determines its essential role in bone homeostasis. J. Exp. Med. 202, 1261-1269.
• Taro Takami, Shuji Terai, Yuichiro Yokoyama, Haruko Tanimoto, Kunihiko Tajima, Koichi Uchida, Takahiro Yamasaki, Isao Sakaida, Hiroshi Nishina, Snorri S. Thorgeirsson and Kiwamu Okita (2005) Human homologue of Maid (HHM) is a useful marker protein in hepatocarcinogenesis. Gastroenterology 128, 1369-1380.
• Saito K, Araki Y, Kontani K, Nishina H, Katada T. (2005) Novel role of the small GTPase Rheb: Its implication in endocytic pathway independent of the activation of mammalian target of rapamycin. J. Biochem. 137, 423-430.
• Shuji Terai, Isao Sakaida, Hiroshi Nishina, and Kiwamu Okita (2005) Lesson from the GFP/CCl4 model−Translational Research Project: the development of cell therapy using autologous bone marrow cells in patients with liver cirrhosis. J. Hepat. Panc. Surg. 12, 203-207.
• Sakaida I, Terai S, Nishina H, Okita K (2005) Development of cell therapy using autologous bone marrow cells for liver cirrhosis. Med Mol Morphol. 38, 197-202.
• Hiroshi Nishina^* and Toshiaki Katada (2005) [book] The Biological Function of JNKKs (MKK4/MKK7 Knockout Mice) in The JNK Signaling Pathway (Anning Lin, eds) pp41-49, Landes Bioscience, Texas.
• Saito, K., Kajiho, H., Araki, Y., Kurosu, H., Kontani, K., Nishina, H., and Katada, T. (2005) Purification and analysis of RIN family − novel Rab5 GEFs. Methods Enzymol. 403: 276-283.

• Publication List before 2005 is here.