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10.
Fukushima T, *Chubachi S, Namkoong H, Asakura
T, Tanaka H, Lee H, Azekawa S, Okada Y, Koike R, Kimura
A, Imoto S, Miyano S, Ogawa S, Kanai T, Fukunaga K, The Japan COVID-19 Task
Force. Clinical significance of pre-diabetes, undiagnosed diabetes, and
diagnosed diabetes on clinical outcomes in COVID-19: Integrative analysis from
the Japan COVID-19 Task Force.@Diabetes Obes Metab. In Press
9.
Otake S, *Chubachi S, Nakagawara
K, Tanaka H, Lee H, Morita A, Fukushima T, Watase M, Kusumoto T, Masaki K,
Namkoong H, Kamata H, Ishii M, Hasegawa N, Harada N, Ueda T, Ueda S, Ishiguro
T, Arimura K, Saito F, Yoshiyama T, Nakano Y, Mutoh Y, Suzuki Y, Murakami K,
Okada Y, Koike R, Kitagawa Y, Kimura A, Imoto S, Miyano S,
Ogawa S, Kanai T, Fukunaga K, The Japan COVID-19 Task Force. Clinical
Clustering with Prognostic Implications in Japanese COVID-19 Patients: Report
from Japan COVID-19 Task Force, a Nation-wide Consortium to Investigate
COVID-19 Host Genetics. BMC Inf Dis, In Press
8.
Namkoong H, Edahiro R, The Japan COVID-19 Task Force. DOCK2 is involved
in host genetics and biology of severe COVID-19. Nature 2022 (doi: 10.1038/s41586-022-05163-5). Online ahead of print.
7.
Wang O, The Japan COVID-19 Task Force. The whole-blood transcriptional
regulation landscape in 465 COVID-19 infected samples from Japan COVID-19 Task
Force, Nature Commun 13(1):4830, 2022.
6.
Lee H, *Chubachi S, *Namkoong H, Tanaka H,
Otake S, Nakagawara K, Morita A, Fukushima T, Watase
M, Kusumoto T, Masaki K, Kamata H, Ishii M, Hasegawa N, Harada N, Ueda T, Ueda
S, Ishiguro T, Arimura K, Saito F, Yoshiyama T, Nakano Y, Mutoh Y, Suzuki Y,
Murakami K, Okada Y, Koike R, Kitagawa Y, Kimura A, Imoto S, Miyano S,
Ogawa S, Kanai T, Fukunaga K, The Japan COVID-19 Task Force. Effects of Mild
Obesity on Outcomes in Japanese Patients with COVID-19: A Nationwide Consortium
to Investigate COVID-19 Host Genetics. Nutr
Diabetes 12(1):38, 2022.
5.
Fukushima T, *Chubachi S, Namkoong H, Otake S, Nakagawara K, Tanaka H, Lee H, Morita A, Watase M, Kusumoto
T, Masaki K, Kamata H, Ishii M, Hasegawa N, Harada N, Ueda T, Ueda S, Ishiguro
T, Arimura K, Saito F, Yoshiyama T, Nakano Y, Mutoh Y, Suzuki Y, Murakami K,
Okada Y, Koike R, Kitagawa Y, Kimura A, Imoto S, Miyano S,
Ogawa S, Kanai T, Fukunaga K; Japan COVID-19 Task Force. U-shaped association
between abnormal serum uric acid levels and COVID-19 severity: Reports from the
Japan COVID-19 Task Force. Int J Infect Dis 2022 (doi: 10.1016/j.ijid.2022.07.014) Online ahead of print.
4.
Yuasa S, Nakajima J, Takatsuki Y, Takahashi Y, Tani-Sassa C, Iwasaki Y,
Nagano K, Sonobe K, Yoshimoto T, Nukui Y, Takeuchi H,
Tanimoto K, Tanaka Y, Kimura A, Ichimura N, *Tohda S. Viral load
of SARS-CoV-2 Omicron is not high despite its high infectivity. J Med
Virol 2022 (doi:
10.1002/jmv.27974) Online ahead of print.
3.
Nii-Trebi NI, Matsuoka S, Kawana-Tachikawa A,
Bonney EY, Abana CZ, Ofori SB, Mizutani T, Ishizaka A, Shiino
T, Ohashi J, Naruse TK, Kimura A, Ishikawa K, *Ampofo
WK, *Matano T. Super high-resolution single-molecule sequence-based typing of
HLA class I alleles in HIV-1 infected individuals in Ghana. PLoS ONE 17(6), e0269390, 2022.
2.
Inagaki N, *Hayashi T, Takei Y, Kosuge H, Suzuki S, Tanimoto K, Chikamori
T, Kimura A. A missense variant
of the RBM20 gene linked to dilated cardiomyopathy, Arg636His, was found in a
multiplex family associated with hypertrophic cardiomyopathy. Hum
Gen Var 9(1): 6, 2022.
1.
#Tani-Sassa C, Iwasaki Y, Ichimura N, Nagano K,
Takatsuki Y, Yuasa S, Takahashi Y, Nakajima J, Sonobe
K, Nukui Y, Takeuchi H, Tanimoto K, Tanaka Y, Kimura A, *Tohda S. Viral loads and profile of the patients infected
with SARS-CoV-2 Delta, Alpha or R.1 variants in Tokyo. J Med
Virol 94(4):1707-1710, 2022.
2021
8. Tanaka T, Lee H, Morita A, *Namkoong H, Chubachi
S, Kabata H, Kamata H, Ishii M, Hasegawa N, Harada N,
Ueda T, Ueda S, Ishiguro T, Arimura K, Saito F, Yoshiyama T, Nakano Y, Mutoh Y,
Suzuki Y, Murakami K, Okada Y, Koike R, Kitagawa Y, Tokunaga K, Kimura A, Imoto S, Miyano S,
Ogawa S, Kanai T, Fukunaga K, and The Japan COVID-19 Task Force. Clinical
characteristics of patients with coronavirus disease (COVID-19): preliminary
baseline report of Japan COVID-19 Task Force, a nation-wide consortium to
research host genetics of COVID-19. Int J
Infect Dis 113: 74-81, 2021.
7. Nagano K, Tani-Sassa C, Iwasaki Y, Takatsuki Y, Yuasa S, Takahashi Y,
Nakajima J, Sonobe K, Ichimura
N, Nukui Y, Takeuchi H, Tanimoto K, Tanaka Y, Kimura A, *Tohda S. SARS-CoV-2 R.1 lineage variants prevailed in Tokyo
in March 2021. J Med Virol 93(12): 6833-6836, 2021.
6. Covid-19 Host Genetic Initiative. Mapping the human
genetic architecture of COVID-19. Nature 600 (7889):472-477, 2021.
5. Kawano H, Kawamura K, Kanda M, Ishijima M, Abe
K, Hayashi T, Matsumoto Y, Kimura A, Maemura K. Histopathological changes of myocytes in
restrictive cardiomyopathy. Med Mol Morphol 54(3): 289-295, 2021.
4. Moriki T, *Kubo T, Sugiura
K, Ochi Y, Baba Y, Hirota T, Yamasaki N, Kimura A, Doi YL, Kitaoka H.
A validation study of the Mayo Clinic phenotype-based genetic test prediction
score for Japanese patients with hypertrophic cardiomyopathy. Circ
J 85(5): 669-674, 2021.
3. Yamada KH, Inagaki N, *Hayashi T, *Kimura A. A novel titin
truncation variant linked to familial dilated cardiomyopathy found in a
Japanese family and its functional analysis in genome-edited model cells. Int
Heart J 62(2): 359-366, 2021. (*;
co-correspondence)
2. Kato S, *Shida H, Okamura T, Zhang X, Miura T, Mukai T, Inoue M, Tsugumine S, Naruse TK, Kimura A, Yasutomi Y,
*Matsuo K. CD8 T cells show protection against highly pathogenic SIV after
vaccination with SIV gene-expressing BCG prime and vaccinia virus/Sendai virus
vector boosts. J Virol 95(4): 01718-01720, 2021.
(*; co-correspondence)
1. #Tanimoto K, #Naruse TK, Matano T, *Kimura A. Development and
evaluation of a rapid and cost-efficient NGS-based MHC class I genotyping
method for macaques by using a prevalent short-read sequencer. Immunogenet 73(2): 175-186, 2021. (#;
equal contribution)
2020
4. *Ueno M,
Takeda A, Yamazawa H, Takei K, Furukawa T, Suzuki Y, Chida-Nagai A, Kimura A. A case report: Twin sisters with
restrictive cardiomyopathy associated with rare mutations in the cardiac
troponin I gene. J Card Cases 23(4): 154-157, 2020.
3. Nakashima Y,
*Kubo T, Ochi Y, Takahashi A, Baba Y, Hirota T, Yamasaki N, Kimura A, Kitaoka H. Long-term clinical impact
of the presence of sarcomere gene mutation in Japanese hypertrophic
cardiomyopathy patients. Circ J 84(19): 1846-1853,
2020.
2. Enomoto H, Mittal N, Inomata T, Arimura T, Izumi T, Kimura A, Fukuda K, *Makino S. Dilated
cardiomyopathy (DCM)-linked heat shock protein 60 (HSP60) mutations cause
upregulation of ROS and autophagy through mitochondrial dysfunction. Cardiovasc Res 117(4): 1118-1131, 2020.
1. Ishii H, Matsuoka S, Ikeda N, Kurihara K, Ueno T,
Takiguchi M, Naruse TK, Kimura A, Yokoyama M, Sato H, *Matano T.
Determination of a T cell receptor of potent CD8+ T cells against simian
immunodeficiency virus infection in Burmese rhesus macaques. Biochem Biophys Res Commun 521(4): 894-899, 2020.
2019
4. Higashikuse Y, Mittal
N, Arimura T, Yoon SH, Oda M, Enomoto H, Kaneda R, Hattori F, Suzuki T,
Kawakami A, Gasch A, Furukawa T, Kudo A, Labeit S,
Fukuda K, Kimura A, *Makino S. Perturbation of the titin/MURF1 signaling
complex is associated with hypertrophic cardiomyopathy in a fish model and in
human patients. Dis Model Mechanism 12.
pii: dmm041103. 2019.
3D*Kikkawa E, Tanaka M, Tsuda TT, Murata K, Naruse TK, Kimura A. Genome structure of MHC Class II b
gene from Humboldt penguin (Spheniscus humboldti).
MHC 26(3): 195-203, 2019.
2. Koizumi S, Naruse TK, *Kimura A: A haplotype of Toll-like receptor 1 is
associated with Buerger disease in Japanese. MHC 26(3): 189-194, 2019
1. An J, Naruse TK, Hinohara K, Soejima
Y, Sawabe M, Nakagawa Y, Kuwahara K, *Kimura A. MRTF-A regulates
proliferation and survival properties of pro-atherogenic macrophages. J Mol Cell Cardiol 133:
26-35, 2019.
11. Naruse
TK, Akari H, Matano T, *Kimura A. Diversity of ULBP5 in the Old
World monkey and divergence of ULBP gene family in primates. Proc Jpn Acad
Ser B Phys Biol Sci. 94(10): 441-453, 2018.
10. Watanabe
T, Kimura A, *Kuroyanagi H. Alternative splicing regulator RBM20 in
cardiomyopathy. Front Mol Biosci
5: 105, 2018
9. *Terao C, Yoshifuji H, Matsumura T, Naruse T, Ishii T, Nakaoka
Y, Kirino Y, Matsuo K, Origuchi T, Shimizu M, Maejima
Y, Amiya E, Tamura N, Kawaguchi T, Takahashi M, Setoh
K, Ohmura K, Watanabe R, Horita T, Atsumi T, Matsukura
M, Miyata T, Kochi Y, Suda T, Tanemoto K, Meguro A,
Okada Y, Ogimoto A, Yamamoto M, Takahashi H, Nakayamada S, Saito K, Kuwana M, Mizuki N, Tabara Y, Ueda
A, Komuro I, Kimura A, Isobe M, Mimori T, Matsuda F. Novel genetic
determinants and an epistasis of LILRA3 and HLA-B*52 in Takayasu arteritis. Proc Natl Acad Sci USA
115(51):13045-13050,
2018.
8. #Takahashi N, #Matsuoka S, Minh TTT, Ba
HP, Naruse TK, Kimura A, Shiino T,
Kawana-Tachikawa A, Ishikawa K, *Matano T, *Thi LAN.
Human leukocyte antigen-associated gag and nef
polymorphisms in HIV-1 subtype A/E-infected individuals in Vietnam. Microb Inf 21(2):113-118, 2018 (#; equal contribution) (*; co-correspondence)
7D#Inagaki N, #*Hayashi T, Takei Y, Tanimoto K, Chikamori T, *Kimura A. Clinical and genetic
background of hypertrophic cardiomyopathy with midventricular obstruction. J Hum Genet 63(12): 1273-1276, 2018 (#;
equal contribution) (*; co-correspondence)
6. *Hayashi
T, Tanimoto K, Yamada K, Tsuda E, Ayusawa
M, Nunoda S, Hosaki A, *Kimura
A. Genetic background of Japanese patients with pediatric hypertrophic and
restrictive cardiomyopathy. J Hum Genet
63(9): 989-996, 2018 (*; co-correspondence)
5DMurayama R, Kimura K, Togo-Ohno M, Yamasaki-Kato Y, Naruse TK,
Yamamoto T, Hayashi T, Ai T, Vatta M,
Iizuka M, Saito M, Wani S, Hiraoka Y, *Kimura A, *Kuroyanagi H.
Phosphorylation of the RSRSP stretch is critical for splicing regulation by
RNA-Binding Motif Protein 20 (RBM20) through nuclear localization. Sci Rep 8: 8970, 2018 (*;
co-correspondence)
4. #Arimura T, #Muchir A, Kuwahara M, Morimoto S, Ishikawa T, Nakao S, Machida N, Tanaka R, Yamane Y, Hayashi T, Kimura A. Overexpression of heart-specific small subunit of myosin light chain phosphatase results in heart failure and conduction disturbance. Am J Physiol-Heart Circ Physiol 314(6): H1192-H1202, 2018. (#; equal contribution)
3. #Yamaguchi
T, #Suzuki T, Sato T, Takahashi A, Watanabe H, Kadowaki A, Natsu M, Inagaki H,
Arakawa S, Nakaoka S, Koizumi Y, Seki S, Adachi S, Fukao A, Fujiwara T, Natsume
T, Kimura A, Komatsu M, Shimizu S, Ito H, Suzuki Y, Penninger JM,
Yamamoto T, Imai Y, Kuba K. The CCR4-NOT deadenylase
complex controls Atg7-dependent cell death and heart function. Sci Signal 11(516), eaan3638, 2018. (#;
equal contribution)
2. Tsujii N,
Hayashi T, Hayashi T, Kimura A, Nishikubo
T. Barth syndrome associated with triple mutation. Pediatr
Int 60(4): 385-387,
2018.
1. #Harada H,
#Hayashi T, Nishi H, Kusaba K, Koga Y, Koga Y,
Nonaka I, Kimura A. Phenotypic expression of a novel desmin
gene mutation: hypertrophic cardiomyopathy followed by systemic myopathy. J Hum Genet 63(2):249-254, 2018. (#; equal
contribution)
6. An J,
Nagaishi T, Watanabe T, Naruse TK, Watanabe M,
*Kimura A. MKL1 expressed in macrophages contributes to the development
of murine colitis. Sci Rep 7: 13650, 2017.
5 #Seki S,
#Nomura T, #Nishizawa M, Yamamoto H, Ishii H, Matsuoka S, Shiino
T, Sato H, Mizuta K, Sakawaki H, Miura T, Naruse
TK, Kimura A, Matano T. Increased in vivo virulence of MHC-adapted
AIDS virus serially-passaged through MHC-mismatched
hosts. PLoS Pathog 13(9): e1006638. (#; equal contribution)
4. Chen Z,
Wang Y, Kuwana M, Xu X, Hu W, Feng X, Wang H, *Kimura A, *Sun L.
HLA-DRB1*04:01 and *12:02 as genetic risk factors for the development of
anti-MDA5 antibodies in patients with dermatomyositis. J Rheumatol@44(9): 1389-1393. 2017. (*; co-correspondence)
3. Sato T,
Sato C, Kadowaki A, Watanabe H, Ho L, Ishida J, Yamaguchi T, Kimura A, Fukamizu A, Penninger JM, Reversade
B, Ito H, Imai Y, *Kuba K. ELABELA-APJ axis protects from pressure overload
heart failure and Angiotensin II-induced cardiac damage. Cardiovasc Res@113(7): 760-769, 2017.
2. #*Gregson,
JM, #Freitag DF, Surendran P, Nathan O. Stitziel NO,
Chowdhury R, Burgess S, Kaptoge S, Gao P, Staley JR, Willeit P, Nielsen SF, Caslake M,
Trompet S, Polfus LM, Kuulasmaa
K, Kontto J, Perola M, Blankenberg S, Veronesi G,
Gianfagna F, Männistö S, Kimura A, Reilly DF, Mijatovic V, Munroe PB,
Ehret GB, Uria-Nickelsen P, Malarstig A, Dehghan A, Sasaoka
T, Kato N, Yamada Y, Kee F, Müller-Nurasyid M, Ferrières J, Arveiler D, Salomaa
V, Thompson SG, Jukema JW, Packard CJ, Majumder AAS, Alam DS, Deloukas P, Schunkert H, Samani NJ, Kathiresan S, Nordestgaard BG, *Saleheen D, *Howson JMM, *Angelantonio
ED, *Butterworth AS, *Danesh J. Genetic invalidation of Lp-PLA2 as a
therapeutic target: lessons for future cardiovascular trials. Eur J Prev Cardiol 24(5):
492-504, 2017. (#; equal contribution) (*; co-correspondence)
1. Kikkawa E, Tanaka M, *Naruse
TK, Tsuda TT, Tsuda M, Murata K, *Kimura A. Diversity of MHC class I
alleles in Spheniscus humboldti.
Immunogenetics 69(2): 113-124,
2017. (*; co-correspondence)
2016
8. Ishii H, Matsuoka S, Nomura T, Nakamura
M, Shiino T, Sato Y, Iwata-Yoshikawa N, Hasegawa H,
Mizuta K, Sakawaki H, Miura T, Koyanagi Y, Naruse
TK, Kimura A, *Matano T. Association of lymph-node antigens with
lower Gag-specific central@memory and higher Env-specific effector-memory CD8+ T-cell
frequencies in a macaque AIDS model. Sci Rep
6: 30153, 2016.
7. *Oikawa M, Sakamoto N, Kobayashi A, Suzuki A,
Yoshihisa A. Yamaki T, Nakazato K, Suzuki H, Saitoh
S, Kiko Y, Nakano H, Hayashi T, Kimura A, Takeishi Y. Familial
hypertrophic obstructive cardiomyopathy with the GLA E66Q mutation and Zebra
body. BMC Cardiovasc Disord
16(1): 83, 2016.
6. *Kawai H, Morimoto S, Takakuwa Y, Ueda A, Inada
K, Sarai M, Arimura T, Mutoh T, Kimura A, Ozaki Y. Hypertrophic
cardiomyopathy accompanied by spinocerebellar atrophy with a novel mutation in
troponin I gene. Int Heart J 57(4):
507-510, 2016.
5. #Iseda S, #Takahashi N, #Poplimont H, Nomura T,
Seki S, Nakane T, Nakamura M, Shi S, Ishii H, Furukawa S, Harada S, Naruse
TK, Kimura A, Matano T, Yamamoto H. Biphasic CD8+ T-cell defense in
elite SIV control by acute-phase passive neutralizing antibody immunization. J Virol 90(14):
6276-6290, 2016. (#; equal contribution)
4. Naruse TK, Sakurai D, Ohtani
H, Sharma G, Sharma SK, Vajpayee M, Narinder KM, Kaur G, *Kimura A. APOBEC3H polymorphisms and
susceptibility to HIV-1 infection in an Indian population. J Hum Genet 61(3): 263-265, 2016.
3. Koizumi A, *Sasano T, Kimura W, Miyamoto
Y, Aiba T, Ishikawa T, Nogami A, Fukamizu S, Sakurada H, Takahashi Y, Nakamura H, Ishikura
T, Koseki H, Arimura T, Kimura A, Hirao K, Isobe M, Shimizu W,
Miura N, *Furukawa T. Genetic defects in a His-Purkinje system transcription
factor, IRX3, cause lethal cardiac arrhythmias. Eur
Heart J@37(18): 1469-1475, 2016.
2. *Kimura A. Molecular genetics and
pathogenesis of cardiomyopathy. J Hum Genet
61(1): 41-50, 2016.
1. *Tanaka T,
*Kimura A. Cardiovascular genetics. J Hum
Genet 61(1): 1, 2016. (*; co-correspondence)
2015
5. Kikkawa E, Tsuda TT, Hosomichi K,
Tsuda M, Inoko H, Kimura A, Naruse TK, Murata
K. Molecular evolutionary analysis of seven species of penguins (order:
Sphenisciformes) in MHC class I gene. [in Japanese] MHC
22(3): 156-163, 2015.
4. Nomura T, Yamamoto H, Ishii H, Akari H, Naruse
TK, Kimura A, Matano T. Broadening of virus-specific CD8+ T-cell
responses is indicative of residual viral replication in aviremic
SIV controllers. PLoS Pathog 11(11): e1005247, 2015.
3. #Kadota C, #Arimura T,
Hayashi T, Naruse TK, Kawai S, Kimura A. Screening of
sarcomere gene mutations in young athletes with abnormal findings in
electrocardiography: identification of a MYH7
mutation and MYBPC3 mutations. J Hum Genet 60 (10): 641-645, 2015 (#;
equal contribution)
2. Sakurai D, Iwatani Y, Ohtani
H, Naruse TK, Terunuma H, Sugiura W, Kimura
A. APOBEC3H polymorphisms
associated with susceptibility to HIV-1 infection and AIDS progression in
Japanese. Immunogenetics 67(4):
253-257, 2015.
1. Ishikawa T, Jou CJ, Nogami A, Kowase
S, Arrington CB, Barnett SM, Harrell DT, Arimura T, Tsuji Y, Kimura A,
Makita N. A novel mutation in a-myosin heavy chain gene is associated
with sick sinus syndrome. Circ Arrhythm Electrophysiol
8(2): 400-408, 2015.
10. Tanaka A, Yuasa S, Mearini G, Egashira T, Seki T,
Kodaira M, Kusumoto D, Kuroda Y, Okata S, Suzuki T, Arimura
T, Makino S, Kimura K, Kimura A, Furukawa T, Carrier L, Nobe K,
Fukuda K. ET-1 induces myofibrillar disarray and contractile vector in
hypertrophic cardiomyopathy-iPS cell-derived
cardiomyocytes. J Am Heart Assoc 3(6):
e001263, 2014.
9. Nomura T, Yamamoto H, Takahashi N, Naruse
TK, Kimura A, Matano T. Identification of SIV Nef
CD8 T cell epitopes restricted by a MHC class I haplotype associated with lower
viral loads in a macaque AIDS model. Biochem Biophys Res Commun 450(2):
942-947, 2014.
8. #Makita N, #Yagihara N, #Crotti L,
#Johnson CN, Beckmann BM, Roh MS, Shigemizu
D, Lichtner P, Ishikawa T, Aiba T, Homfray T, Behr ER, Klug D, Denjoy
I, Mastantuono E, Theisen D, Tsunoda T, Satake W, Toda T, Nakagawa H, Tsuji Y,
Tsuchiya T, Yamamoto H, Miyamoto Y, Endo N, Kimura A, Ozaki K, Motomura H, Suda K, Tanaka T, Schwartz PJ, Meitinger T, Kääb S, Guichney P, Bhuiyan ZA, Shimizu W, Watanabe H, Chazin WJ,
George AL. Novel calmodulin (CALM2) mutations associated with congenital
arrhythmia susceptibility. Circ Cardiovasc Genet
7(4): 466-474, 2014. (#; equal contribution)
7. Okada S, Suzuki Y, Arimura T, Kimura
A, Narumi H, Hasegawa S. A novel de novo mutation of b-cardiac
myosin heavy chain gene found in a 12-year-old boy with hypertrophic
cardiomyopathy. J Genet 93(2):
557-560, 2014.
6DNaruse TK, Akari H, Matano T, Kimura
A. Divergence and diversity of ULBP2 genes in rhesus and cynomolgus
macaques. Immunogenetics 66(3):161-170,
2014.
5. #Katsuumi G, #Shimizu W, Watanabe H,
Noda T, Nogami A, Ohkubo K, Makiyama T, Takehara N,
Kawamura Y, Hosaka Y, Sato M, Fukae S, Chinushi M, Oda H, Okabe M, Kimura A, Maemura K, Watanabe I, Kamakura S, Horie M, Aizawa Y,
Makita N, Minamino T. Efficacy of bepridil to prevent ventricular fibrillation
in severe form of early repolarization syndrome. Int
J Cardiol 172(2): 519-522, 2014. (#; equal
contribution)
4. Kimura A. Departure from the
Hardy-Weinberg equilibrium. Gene 537(2): 357,
2014.
3. Nishio A, Noguchi Y, Sato T, Naruse
TK, Kimura A, Takagi A, Kitamura K. A DFNA5 mutation identified in Japanese families with autosomal
dominant hereditary hearing loss. Ann Hum Genet
78(2): 83-91, 2014.
2. #Pinós T, #Fuku N, Cámara Y, Arai Y,
Abe Y, Rodríguez-Romo G, Garatachea N, Santos-Lozano
A, Miro-Casas E, Ruiz-Meana M, Otaegui I, Murakami H, Miyachi M, Garcia-Dorado
D, Hinohara K, Andreu AL, Kimura A,
Hirose N, Lucia A. The rs1333049 polymorphism on locus 9p21.3 and extreme
longevity in Spanish and Japanese cohorts. Age 36(2): 933-943,
2014. (#; equal contribution)
1. Iwamoto N, Takahashi N, Seki S,
Nomura T, Yamamoto H, Inoue M, Shu T, Naruse TK, Kimura A, Matano
T. Control of SIV replication by vaccine-induced Gag- and Vif-specific CD8+ T
cells. J Virol
88(1): 425-433, 2014.
2013
19. An J,
Kimura A. IkBL mapped within the HLA region is
a novel regulator of alternative splicing involved in the pathogenesis of
immune-related diseases. MHC 20(3):
191-197, 2013.
18. #Ichihara
S, #Yamamoto K, Asano H, Nakatochi M, Sukegawa M, Ichihara G, Izawa H, Hirashiki
A, Takatsu MF, Umeda H, Iwase M, Inagaki H, Hirayama H, Sone T, Nishigaki K, Minatoguchi S, Cho
MC, Jang Y, Kim HS, Park JE, Tada-Oikawa S, Kitajima H, Matsubara T, Sunagawa
K, Shimokawa H, Kimura A, Lee JY, Murohara T,
Inoue I, Yokota M. Identification of a glutamic acid repeat polymorphism of
ALMS1 as a novel genetic risk marker for early-onset myocardial infarction by
genome-wide linkage analysis. Circ Cardiovasc
Genet. 6(6): 569-578, 2013. (#; equal contribution)
17. Sato T,
Suzuki T, Watanabe H, Kadowaki A, Fukamizu A, Liu PP,
Kimura A, Ito H, Penninger JM, Imai Y, Kuba K. Apelin is a positive
regulator of ACE2 in failing hearts. J Clin
Invest. 123(12): 5203-5211, 2013.
16. #Arimura
T, #Takeya R, Ishikawa T, Yamano T, Matsuo A, Tatsumi T, Nomura T, Sumimoto H, Kimura A. Dilated
cardiomyopathy-associated FHOD3 variant impairs the ability to induce
activation of transcription factor SRF. Circ J
77(12): 2990-2996, 2013. (#; equal contribution)
15. An J,
Nakajima T, Shibata H, Arimura T, Yasunami
M, Kimura A. A novel link of HLA locus to the regulation of immunity
and infection: NFKBIL1 regulates alternative splicing of human immune-related
genes and influenza virus M gene. J Autoimmun 47: 25–33, 2013.
14. Nakane T,
Nomura T, Shi S, Nakamura M, Naruse TK, Kimura A, Matano T,
Yamamoto H. Limited impact of passive non-neutralizing antibody immunization in
acute SIV infection on viremia control in rhesus macaques. PLoS ONE
8(9): e73453, 2013.
13. #Sakurai
D, #Zhao J, #Deng Y, Kelly JA, Brown EE, Harley JB, Bae SC, Alarcόn-Riquelme ME, Edberg JC, Kimberly RP, Ramsey-Goldman R, Petri MA,
Reveille JD, Vilá LM, Alarcón GS, Kaufman KM, Vyse
TJ, Jacob CO, Gaffney PM, Sivils KM, James JA, Kamen DL, Gilkeson GS, Niewold
TB, Merrill JT, Scofield RH, Criswell LA, Stevens AM21, Boackle
SA, Kim JH, Choi J, Pons-Estel BA, Freedman BI, Anaya JM, Martin J, Yu CY,
Chang DM, Song YW, Langefeld CD, Chen W, Grossman JM, Cantor RM, Hahn BH, Tsao
BP. Preferential Binding to Elk-1 by SLE-Associated IL10 risk allele
up-regulates IL10 expression. PLoS Genetics 10, e1003870, 2013.
12. Terao C, Yoshifuji H, Kimura A, Matsumura T, Ohmura K,
Takahashi M, Shimizu M, Kawaguchi T, Chen Z, Naruse TK, Sato-Otubo A, Ebana Y, Maejima Y,
Kinoshita H, Murakami K, Kawabata D, Wada Y, Narita I, Tazaki
J, Kawaguchi Y, Yamanaka H, Yurugi K, Miura Y,
Maekawa T, Ogawa S, Komuro I, Nagai R, Yamada R, Tabara Y, Isobe M, Mimori T,
Matsuda F. Two susceptibility loci to Takayasu arteritis reveal a synergistic
role of the IL12B and HLA-B regions in a Japanese population. Am J Hum Genet 93(2): 289-297. 2013.
11. Terao C, Yoshifuji H, Ohmura K, Murakami K, Kawabata D, Yurugi K, Tazaki J, Kinoshita H, Kimura
A, Akizuki M, Kawaguchi Y, Yamanaka H, Miura Y,
Maekawa T, Saji H, Mimori T, Matsuda F. Association of Takayasu arteritis with
HLA-B*67:01 and two amino acids in HLA-B protein. Rheumatol 52(10): 1769-1774,
2013.
10. Arimura T, Onoue K, Takahashi-Tanaka
Y, Ishikawa T, Kuwahara M, Setou M, Shigenbu
S, Yamaguchi K, Bertrand AT, Machida N, Takayama K, Fukusato
M, Tanaka R, Somekawa T, Nakano T, Yamane Y, Kuba K,
Imai Y, Saito N, Bonne G, Kimura A. Nuclear accumulation of androgen
receptor in gender difference of dilated cardiomyopathy due to lamin A/C mutations. Cardiovasc
Res 99(3): 382-394, 2013.
9. #Crocini C, #Arimura T, Reischmann S, Eder A, Braren I, Hansen A, Eschenhagen T, Kimura A, Carrier L, Impact of ANKRD1
mutations associated with hypertrophic cardiomyopathy on contraction parameters
of engineered heart tissue. Basic Res Cardiol 103(3): 349, 2013. (#; equal
contribution)
8. #Nakayama EE, #Nakajima T, Kaur
G, Miyama J, Terunuma H, Mehra NK, Kimura A,
Shioda T. A naturally occurring single amino acid substitution in human TRIM5ż linker region affects its
anti-HIV-1 activity and susceptibility to HIV-1 infection. AIDS Res Hum Retroviruses 29(6):
919-924, 2013. (#; equal contribution)
7. Chan K, Patel RS, Newcombe P, Nelsone CP, Qasim A, Epstein SE, Burnett S, Vaccarino V,
Zafari AM, Shah SH, Anderson JL, Carlquist JF, Hartiala
J, Allayee H, Hinohara
K, Lee BS, Erl A, Ellis KL, Goel A, Schaefer AS, Eddine N, Mokhtari NEE,
Goldstein BA, Hlatky MA, Go AS, Shen GQ, Gong Y, Pepine
C, Laxton RC, Wittaker JC, Tang WHW, Johnson JA, Wang
QK, Assimes TL, Nöthlings
U, Farrall M, Watkins H, Richards MA, Cameron VA, Muendlein
A, Drexel H, Koch W, Park JE, Kimura A, Shen WF, Simpson IA, Hazen SL,
Horne BD, Hauser ER, Quyyumi AA, Reilly MP, Samani
NJ, Ye S. Association between the chromosome 9p21 locus and angiographic
coronary artery disease burden - a collaborative meta-analysis. J Am Col Cardiol 61(9):
957-970, 2013.
6. Deng Y, Zhao J, Sakurai D,
Kaufman KM, Edberg JC, Kimberly RP, Kamen DL, Gilkeson GS, Jacob CO, Scofield RH,
Langefeld CD, Kelly JA, Ramsey-Goldman R, Petri MA, Reveille JD, Vilá LM, Alarcón GS, Vyse TJ, Pons-Estel BA, Freedman BI,
Gaffney PM, Sivils KM, James JA, Gregersen PK, Anaya JM, Niewold TB, Merrill
JT, Criswell LA, Stevens AM, Boackle SA, Cantor RM,
Chen W, Grossman JM, Hahn BH, Harley JB, Alarcόn-Riquelme ME. Brown EE, Tsao BP.
MicroRNA-3148 modulates allelic expression of Toll-like receptor 7 variant
associated with systemic lupus erythematosus. PLoS
Genetics 9(2): e1003336, 2013.
5. #Kashiwakura Y, #Sakurai D, Kanno
Y, Hashiguchi M, Kobayashi A, Kurosu A, Tokudome S, Kobata T, Kojima H.
CD2-mediated regulation of peripheral CD4(+) CD25(+) regulatory T cell
apoptosis accompanied by downregulation of Bim. Immunology 139(1): 48-60, 2013 (#; equal contribution)
4. Takahashi N, Nomura T, Takahara Y,
Yamamoto H, Shiino T, Takeda A, Inoue M, Iida A, Hara
H, Shu T, Hasegawa M, Sakawaki H, Miura T, Igarashi
T, Koyanagi Y, Naruse TK, Kimura A, Matano T. A novel protective
MHC-I haplotype not associated with dominant Gag-specific CD8+ T-cell responses
in SIVmac239 infection of Burmese rhesus macaques. PLoS ONE 8(1): e54300, 2013.
3. Ishikawa T, Takahashi N, Ohno S,
Sakurada H, Nakamura K, On YK, Park JE, Makiyama T,
Horie M, Arimura T, Makita N, Kimura A. Novel SCN3B mutation
associated with Brugada syndrome affects
intracellular trafficking and function of Nav1.5. Circ
J 77(4): 959-967, 2013.
2. Sharma G, Ohtani H, Kaur G, Naruse
TK, Sharma SK, Vajpayee M, Kimura A, Mehra NK. Status of TIM-1 exon
4 haplotypes and CD4+T cell counts in HIV-1 seroprevalent
North Indians. Hum Immunol 74(2):
163-165, 2013.
1. Kimura A, Ohtani H, Naruse
TK, Nakajima T, Akari H, Mori K, Matano T. Evolutional medicine: an
approach to identify the human genome diversity associated with HIV-1/AIDS. In Proceeding
of the International Conference on Emerging Frontiers and Challenges in
HIV/AIDS Research. (Bandivdekar A, Puri
CP, eds.), pp11-23, Varum Enderprises, Mumbai, 2013.
2012
15. Minami T, Kuwahara K, Nakagawa Y, Takaoka M,
Kinoshita H, Nakao K, Kuwabara Y, Yamada Y, Yamada C, Shibata J, Usami S,
Yasuno S, Nishikimi T, Ueshima
K, Sata M, Nakano H, Seno T, Kawahito Y, Sobue K, Kimura A, Nagai R, Nakao K. Reciprocal
expression of MRTF-A and myocardin is crucial for
pathological vascular remodeling in mice. EMBO J 31(23): 4428-4440, 2012.
14. #Ishikawa T, #Sato A, Marcou CA,
Tester DJ, Ackerman MJ, Crotti L, Schwartz PJ, On YK, Park JE, Nakamura K,
Hiraoka M, Nakazawa K, Sakurada H, Arimura T, Makita N, Kimura A.
A novel disease gene for Brugada syndrome: sarcolemmal membrane-associated protein gene mutations
impair intracellular trafficking of hNav1.5. Circ
Arrhythm Electrophysiol
5(6): 1098-1107, 2012.
13. Sato A, Sakamoto N, Ando K, Kaneshiro T, Uekita H, Sugimoto K, Yamaki T, Kunii H, Nakazato K, Suzuki
H, Saitoh S, Sato M, Tamagawa K, Arimura T, Kimura
A, Takeishi Y. Dilated phase of hypertrophic cardiomyopathy caused by two
different sarcomere mutations, treated with surgical left ventricular
reconstruction and cardiac resynchronization therapy with a defibrillator. Intern Med 51(18): 2559-2564, 2012.
12. Xi Y, Ai T, De Lange E, Li Z, Wu G, Brunelli L,
Kyle WB, Cheng J, Ackerman MJ, Kimura A, Weiss JN, Qu Z, Kim JJ,
Faulkner G, Vatta M: Loss-of-function of hNav1.5 by
ZASP1-D117N associated with intraventricular conduction disturbances in left
ventricular noncompaction. Circ Arrhythm Electrophysiol
5(5): 1017-1026, 2012.
11. Watanabe H, Nogami A, Ohkubo K, Kawata H,
Hayashi Y, Ishikawa T, Makiyama T, Nagao S, Yagihara N, Takehara N, Kawamura Y, Sato A, Okamura K,
Hosaka Y, Sato M, Fukae S, Chinushi
M, Oda H, Okabe M, Kimura A, Maemura K,
Watanabe I, Kamakura S, Horie M, Aizawa Y, Shimizu W, Makita N. Clinical
characteristics and risk of arrhythmia recurrences in patients with idiopathic
ventricular fibrillation associated with early repolarization. Int J Cardiol 159(3): 238-240,
2012.
10. Ohtani H, Naruse TK, Iwasaki Y,
Ishida T, Akari H, Matano T, Kimura A. Lineage-specific evolution of
T-cell immunoglobulin and mucin domain 1 gene in the primates. Immunogenetics 64(9): 669-678., 2012.
9. Tabara Y, Kohara K, Miki T; Millennium Genome
Project for Hypertension (Fujioka A, Hanada H, Hata A, Hirawa N, Hiura Y, Imai
Y, Inoko H, Itoh N, Iwai N, Kulski
JK, Kamide K, Kato N, Osaka TK, Kawamoto R, Kawano Y, Kimura A, Kita Y,
Kohara K, Kokubo Y, Mano H, Mano S, Miki T, Miyata T, Mizuki N, Morisaki T,
Nakamura Y, Nakao K, Nakayama T, Nakura J, Ogawa M, Ogihara T, Ohkubo T, Ohno S, Oka A, Okamura T, Saruta T,
Sekine A, Shiwa T, Soma M, Sugano S, Tabara Y, Tajima A, Takahashi N, Takashima
N, Takeuchi F, Tokunaga K, Tomoike H, Umemura S,
Yamane T, Yanai K, Yasunami M, Yatsu K, Yoshida T, Tabara Y). Hunting for genes for
hypertension: the Millennium Genome Project for Hypertension. Hypertension Res 2012; 35(6): 567-573.
8. Nomura T, Terahara K, Yamamoto H, Shiino T, Takahashi N, Nakane T, Iwamoto N, Ishii H,
Tsukamoto T, Kawada M, Matsuoka S, Takeda A, Terahara K, Tsunetsugu-Yokota
Y, Iwata-Yoshikawa N, Hasegawa H, Sata T, Naruse TK, Kimura A,
Matano T. Association of major histocompatibility complex class I haplotypes
with disease progression after simian immunodeficiency virus challenge in
Burmese rhesus macaques. J Virol
86(12): 6481-6490, 2012
7. Watanabe H, Nogami A, Ohkubo K, Kawata H, Hayashi
Y, Ishikawa T, Nagao S, Yagihara N, Takehara
N, Kawamura Y, Sato A, Okamura K, Sato M, Hosaka Y, Fukae
S, Chinushi M, Oda H, Okabe H, Kimura A, Maemura K, Watanabe I, Kamakura S, Aizawa Y, Shimizu W,
Makita N. Similarities and differences in genetic and clinical characteristics
between early repolarization syndrome and Brugada
syndrome. Circ Arrhythm
Electrophysiol 5(2): e60-e61, 2012
6. #Purevjav E, #Arimura T, Augustin S, Huby A-C, Takagi K, Nunoda S, Kearney DL, Taylor MD, Terasaki F, Bos JM, Ommen
SR, Shibata H, Takahashi M, Itoh-Satoh M, McKenna W,
Murphy RT, Labeit S, Yamanaka Y, Machida N, Park JE,
Alexander PMA, Weintraub RG, Kitaura Y, Ackerman MJ, Kimura
A, Towbin JA. Molecular basis for clinical heterogeneity in inherited
cardiomyopathies due to myopalladin mutations. Hum
Mol Genet 21(9): 2039-2053, 2012. (#; equal contribution)
5. #Otsuka H, #Arimura T, Abe T, Kawai H, Aizawa Y, Kubo T,
Kitaoka H, Nakamura H, Nakamura K, Okamoto H, Ichida F, Ayusawa
M, Nunoda S, Isobe M, Matsuzaki M, Doi YL, Fukuda K,
Sasaoka T, Izumi T, Ashizawa N, Kimura A.
Prevalence and distribution of sarcomeric gene
mutations in Japanese patients with familial hypertrophic cardiomyopathy. Circ J 76(2): 453-461, 2012. (#; equal
contribution)
4. Bertrand AT, Renou L, Papadopoulos A, Beuvin
M, Lacène E, Massart C,
Ottolenghi C, Decostre V, Maron S, Schlossarek S,
Cattin ME, Carrier L, Malissen M, Arimura T,
Bonne G. DelK32-lamin A/C has abnormal location and induces incomplete tissue
maturation and severe metabolic defects leading to premature death. Hum Mol Genet 21(5): 1037-1048, 2012.
3. #Saito Y, #Naruse TK, Akari H, Matano T, Kimura A.
Diversity of MHC class I haplotypes in cynomolgus macaques. Immunogentics 64(2): 131-141,
2012. (#; equal contribution)
2. Takaki A, Yamazaki A, Maekawa T, Shibata H, Hirayama K, Kimura A,
Hirai H, Yasunami M. Positive selection of Toll-like
receptor 2 polymorphisms in two closely related old world monkey species,
rhesus and Japanese macaques. Immunogenetics
64(1): 15-29, 2012.
1. Ishii H, Kawada M, Tsukamoto T, Yamamoto H, Matsuoka S, Shiino T, Takeda A, Inoue M, Iida A, Hara H, Shu T,
Hasegawa M, Naruse TK, Kimura A, Takiguchi M, Matano T. Impact of
vaccination on cytotoxic T lymphocyte immunodominance and cooperation against
simian immunodeficiency virus replication in rhesus macaques. J Virol 86(2):
738-745, 2012.
12. Watanabe H, Nogami A, Ohkubo K, Kawata H, Hayashi Y, Ishikawa T,
Nagao S, Yagihara N, Takehara N, Kawamura Y, Sato A,
Okamura K, Sato M, Hosaka Y, Fukae S, Chinushi M, Oda H, Okabe H, Kimura A, Maemura K, Watanabe I, Kamakura S, Aizawa Y, Shimizu W,
Makita N. Electrocardiographic characteristics and SCN5A mutations in idiopathic
ventricular fibrillation associated with early repolarization. Circ Arrhythm Electrophysiol. 4(6): 874-881, 2011.
11. Takahashi M, Chen Z, Watanabe K, Kobayashi H, Nakajima
T, Kimura A, Izumi Y. Toll-like receptor 2 gene polymorphisms
associated with aggressive periodontitis in Japanese. Open Dent J. 5: 190-194, 2011.
10. Arimura T, Ishikawa T, Nunoda
S, Kawai S, Kimura A. Dilated cardiomyopathy-associated BAG3 mutations
impair the Z-disc assembly and enhance the sensitivity to apoptosis in cardiomyocytes.
Hum Mutat.
32(12): 1481-1491, 2011.
9. Nakamura M, Takahara Y, Ishii H, Sakawaki H,
Horiike M, Miura T, Igarashi T, Naruse TK, Kimura
A, Matano T, Matsuoka S. Major histocompatibility complex class
I-restricted cytotoxic T lymphocyte responses during primary simian
immunodeficiency virus infection in Burmese rhesus macaques. Microbiol Immunol. 55(11): 768-773, 2011.
8. Kubo T, Kitaoka H, Okawa M, Baba Y, Hirota T, Hayato K, Yamasaki N,
Matsumura Y, Otsuka H, Arimura T, Kimura A, Doi YL.
Genetic screening and double mutation in Japanese patients with hypertrophic
cardiomyopathy. Circ J. 75(11):
2654-2659, 2011.
7. Naruse TK, Okuda Y, Mori K, Akari H, Matano T, Kimura
A. ULBP4/RAET1E is highly polymorphic in the Old World monkey. Immunogenetics 63(8): 501-509, 2011.
6. Takahara Y, Matsuoka S, Kuwano T, Tsukamoto
T, Yamamoto H, Ishii H, Nakasone T, Takeda A, Inoue M, Iida A, Hara H, Shu T,
Hasegawa M, Sakawaki H, Horiike
M, Miura T, Igarashi T, Naruse TK, Kimura A, Matano T. Dominant
induction of vaccine antigen-specific cytotoxic T lymphocyte responses after
simian immunodeficiency virus challenge. Biochem Biophys Res Commun. 408(4):
615-619, 2011.
5. Kimura A. Contribution of genetic factors to the
pathogenesis of dilated cardiomyopathy. Circ J. 75(7):
1756-1765, 2011.
4. Chen Z, Nakajima
T, Inoue Y, Kudo T, Jibiki M, Iwai T, Kimura A.
A single nucleotide polymorphism in the 3f-untranslated region
of MyD88 gene is associated with Buerger disease but not with Takayasu
arteritis in Japanese. J Hum Genet. 56(7): 545-547, 2011.
3. Ohtani H,
Nakajima T, Akari H, Ishida T, Kimura A. Molecular evolution of
immunoglobulin superfamily genes in primates. Immunogenetics
63(7): 417-428, 2011
2. Yanagimachi
M, Miyamae T, Naruto T, Hara T, Kikuchi M, Hara R, Imagawa T, Mori M. Kaneko T,
Goto H, Morita S, Mizuki N, Kimura A, Yokota
S. Association of HLA-A*02:06 and DRB1*09:01 with clinical subtypes of juvenile
idiopathic arthritis. J Hum Genet. 56(3):
196-199, 2011.
1. Kimura A.
Cardiomyopathy, sarcomeropathy and Z-diskopathy. In Genes and Cardiovascular Function. (Dhalla NS,
Nagano M, Ostadal B, eds.), pp225-234, Springer, New
York, 2011.
16. Li Z, Ai
T, Samani K, Xi Y, Tzeng HP, Xie M, Taylor MD, Wu S, Ge S, Dong JW. Cheng J,
Ackerman MJ, Kimura A, Sinagra G, Brunelli L, Faulkner G, Vatta M. A ZASP missense mutation, S196L, leads to
cytoskeletal and electrical abnormalities in a mouse model of cardiomyopathy. Circ Arrhythm Electrophysiol. 3(6): 646-656,
2010.
15. Shichi
D, Arimura T, Ishikawa T, Kimura A. Heart-specific
small subunit of myosin light chain phosphatase activates Rho-associated kinase
and regulates phosphorylation of myosin phosphatase target subunit 1. J Biol Chem. 285(44): 33680-33690, 2010.
14. Purevjav E, Varela J, Morgado M, Kearney DL, Li H, Taylor
MD, Arimura T, Moncman CL, McKenna W, Labeit S, Vatta M, Bowles NE, Kimura
A, Boriek AM, Towbin JA. Nebulette mutations are
associated with dilated cardiomyopathy and endocardial fibroelastosis. J Am Coll Cardiol.
56(18): 1493-1502, 2010.
13. Chen Z,
Nakajima T, Tanabe N, Hinohara K, Sakao S,
Kasahara Y, Tatsumi K, Inoue Y, Kimura A. Susceptibility to chronic
thromboembolic pulmonary hypertension may be conferred by miR-759 via its
targeted interaction with polymorphic fibrinogen alpha gene. Hum Genet. 128(4): 443-452, 2010.
12. Sugimoto
C, Watanabe S, Naruse T, Kajiwara E, Shiino T,
Umano N, Ueda K, Sato H, Ohgimoto
S, Hirsh V, Villinger F, Ansari AA, Kimura A, Miyazawa M, Suzuki Y,
Yamamoto N, Nagai Y, Mori K. Protection of macaques with diverse MHC genotypes
against a heterologous SIV by vaccination with a deglycosylated
live-attenuated SIV. PLoS ONE 5(7): e11678, 2010.
11. Naruse
TK, Chen Z, Yanagida R, Yamashita T, Saito Y,
Mori K, Akari H, Yasutomi Y, Miyazawa M, Matano T, Kimura A. Diversity
of MHC class I genes in Burmese-origin rhesus macaque. Immunogenetics 62(9): 601-611, 2010.
10. Hitomi N,
Kubo T, Kitaoka H, Hirota T, Hamada T, Hoshikawa E,
Hayato K, Okawa M, Kimura A, Doi YL. A frameshift deletion mutation in
the cardiac myosin-binding protein C gene was associated with dilated phase of
hypertrophic cardiomyopathy and dilated cardiomyopathy. J Cardiol. 56(2):
189-196.
9. #Choi JO,
#You CW, Nah JC, Park JR, Lee BS, Choi BY, Cho BY, Lee SC, Park SW, Kimura A,
Park JE. Long-term outcome of four Korean families with hypertrophic
cardiomyopathy caused by four different mutations. Clin
Cardiol. 33(7): 430-438,
2010. (#; equal contribution)
8. An J,
Nakajima T, Kuba K, Kimura A. Losartan inhibits
LPS-induced inflammatory signaling by PPAR-gamma-dependent mechanism in human
THP-1 macrophage. Hypertension Res. 33(8):
831-835, 2010.
7. Itaya S, Nakajima T, Kaur G, Terunuma H, Ohtani H, Mehra N, Kimura A. No
evidence an association between the APOBEC3B deletion polymorphism and
susceptibility to HIV infection and AIDS in Japanese and Indian populations. J Infect Dis. 202(5): 815-816, 2010.
6.
#Wichukchinda N, #Nakajima T, Saipradit N,
Nakayama EE, Ohtani H, Rojanawiwat A,
Pathipvanich P, Ariyoshi K, Sawanpanyalert P, Shioda
T, Kimura A. TIM1 haplotype may control the disease progression to AIDS
in a HIV-1-infected female cohort in Thailand. AIDS
24(11): 1625-1631, 2010 (#;
equal contribution)
5. Takahashi
M, Kimura A. HLA and CTLA4 polymorphisms may confer a synergistic
risk in the susceptibility to Gravesf disease. J Hum Genet.
55(5): 323-326, 2010.
4. #Neely1 GG, #Kuba K, #Cammarato A, Isobe K, Amann S, Zhang L,
Murata M, Elmen L, Gupta V, Arora S, Sarangi R, Dan D, Fujisawa S, Usami T, Xia
CP, Keene AC, Alayari NA, Yamakawa H, Elling U,
Berger C, Novatchkova M, Koglgruber
R, Fukuda K, Nishina H, Isobe M, Pospisilik JA, Imai
Y, Pfeufer A, Hicks A, Pramstaller
PP, Subramaniam S, Kimura A, Ocorr K, Bodmer
R, Penninger JM. A global in vivo Drosophila RNAi screen identifies NOT3 as a
conserved regulator of heart function. Cell
141(1): 142-153, 2010. (#; equal contribution)
3. Kimura A. Molecular basis of hereditary cardiomyopathy:
abnormalities in calcium sensitivity, stretch response, stress response and
beyond. J Hum Genet. 55(2): 81-90,
2010.
2. Arimura T, Sato R, Machida N, Bando H, Zhang DY, Morimoto S,
Tanaka R, Yamane Y, Bonne G, Kimura A. Improvement of left ventricular
dysfunction and of survival prognosis of dilated cardiomyopathy by
administration of calcium sensitizer SCH00013 in a mouse model. J Am Coll Cardiol. 55(14): 1503-1505, 2010.
1. Matuda S, Arimura T, Kimura A,
Takekura H, Ohta S, Nakano K. A novel protein found
in the I bands of myofibrils is produced by alternative splicing of the DLST
gene. Biochim Biophys Acta. 1800(1): 31-39, 2010.
21. Sato A, Arimura T, Makita N, Ishikawa T, Aizawa
Y, Ushinohama H, Aizawa Y, Kimura A. Novel
mechanisms of trafficking defect caused by KCNQ1 mutations found in long QT
syndrome. J Biol Chem. 284(50):
35122-35133, 2009.
20. Hinohara K, Ohtani H, Nakajima
T, Sasaoka T, Sawabe M, Lee BS, Ban J, Park JE,
Izumi T, Kimura A. Validation of eight genetic risk factors in East
Asian populations replicated the association of BRAP with coronary artery
disease. J Hum Genet. 54(11): 642–646, 2009.
19. #Nakajima T, #Nakayama EE, Kaur G, Terunuma
H, Mimaya J, Ohtani H, Mehra N, Shioda Y, Kimura
A. Impact of novel TRIM5a variants, Gly110Arg and G176del, on the
anti-HIV-1 activity and the susceptibility to HIV-1 infection. AIDS 23(16): 2091-2100, 2009. (#; equal
contribution)
18. Hinohara K, Nakajima T,
Sasaoka T, Sawabe M, Lee BS, Ban J, Park JE, Izumi T,
Kimura A. Validation of the association between AGTRL1 polymorphism and
coronary artery disease in Japanese and Korean populations. J Hum Genet. 54(9): 554-556, 2009.
17. Romphruk AV, Romphruk
A, Naruse TK, Raroengjai S, Puapairoj C, Inoko H, Leelayuwat C. Polymorphisms
of NKG2D ligands: diverse RAET1/ULBP genes in Northeastern Thais. Immunogenetics 61(9): 611-617, 2009.
16. Park YE, Hayashi YK, Bonne G, Arimura T, Noguchi S, Nonaka I,
Nishino I. Autophagic degradation of nuclear components in mammalian cells. Autophagy 5(6): 795-804, 2009.
15. Hinohara K, Nakajima T, Yasunami M, Houda S, Sasaoka T,
Yamamoto K, Lee BS, Shibata H, Takahashi TY, Arimura T, Sato
A, Naruse T, Ban J, Inoko H, Yamada Y, Sawabe M, Park JE, Izumi T, Kimura A. Megakaryoblastic leukemia factor-1 gene in the
susceptibility to coronary artery disease. Hum
Genet. 126(4): 539-547, 2009.
14. Kang EH, Yamaguchi T, Tajima A, Nakajima T, Tomoyasu Y,
Watanabe M, Yamaguchi M, Park SB, Maki K, Inoue I. Association of the growth
hormone receptor gene polymorphisms with mandibular height in a Korean
population. Arch Oral Biol. 54(6):
556-562, 2009.
13. Tomoyasu Y, Yamaguchi T, Tajima A, Nakajima T, Inoue I, Maki
K. Further evidence for an association between mandibular height and the growth
hormone receptor gene in a Japanese population. Am
J Orthod Dentofacial Orthop.
136(4): 536-541, 2009.
12. Kano T, Mori T, Kimura A. Gender ratio distortion in abortuses and live births from patients with recurrent
spontaneous abortion. Am J Reprod
Immunol. 62(3): 125-127, 2009.
11. Nakajima T, Kimura A. Comparative genomics: insight
into human health and disease. In The HLA
Complex in Biology and Medicine: a resource book. (Mehra N, ed),
pp566-589, Jaypee Brothers Medical Publishers (P) Ltd. New Delhi, 2009.
10. #Arimura
T, #Bos MJ, Sato A, Kubo T, Okamoto H, Nishi H, Harada H,
Koga Y, Moulik M, Doi YL, Towbin JA, Ackerman MJ, Kimura A. Cardiac
ankyrin repeat protein gene (ANKRD1) mutations in hypertrophic cardiomyopathy. J Am Coll Cardiol. 54(4):
334-342, 2009. (#; equal contribution)
9. Moulik M, Vatta M, Witt SH, Alora AM, Murphy
RT, McKenna WJ, Boriek A, Oka K, Labeit
S, Bowles NE, Arimura T, Kimura A, Towbin JA. ANKRD1 -the gene
encoding cardiac ankyrin repeat protein- is a novel dilated cardiomyopathy
gene. J Am Coll Cardiol.
54(4): 325-333, 2009.
8. Kimura A. Does a gene polymorphism predisposing to the
intermediate phenotype predict the risk of disease? Circ
J. 73(6): 1016-1017, 2009.
7. #Arimura T, #Inagaki N, Hayashi T, Shichi D,
Sato A, Hinohara K, Vatta M, Towbin JA, Chikamori T,
Yamashina A, Kimura A. Impaired binding of ZASP/Cypher with
phosphoglucomutase 1 is associated with dilated cardiomyopathy. Cardiovasc Res. 83(1): 80-88, 2009. (#; equal
contribution)
6. Kikkawa EF,
Tsuda TT, Sumiyama D, Naruse TK, Fukuda M,
Kurita M, Wilson RP, LeMaho Y, Miller GD, Tsuda M,
Murata K, Kulski JK, Inoko
H. Trans-species polymorphism of the Mhc class II
DRB-like gene in banded penguins (genus Spheniscus). Immunogenetics 61(5): 341-352, 2009.
5. Hinohara K, Nakajima T, Sasaoka T, Sawabe M, Lee BS, Ban J, Park JE, Izumi T, Kimura A.
Replication studies for the association of PSMA6 polymorphism with coronary
artery disease in East Asian populations. J Hum
Genet. 54(4): 248-251, 2009.
4. Shichi D,
Ota M, Katsuyama Y, Inoko
H, Naruse T, Kimura A. Complex divergence at a microsatellite
marker C1_2_5 in lineage of HLA-Cw/-B haplotype. J Hum Genet. 54(4): 224-229, 2009.
3. #Ueda K,
#Hirano Y, Higashiuesato Y, Aizawa Y, Hayashi
T, Inagaki N, Tana T, Ohya Y, Takishita S, Muratani H, Hiraoka
M, Kimura A. Role of HCN4 channel in preventing ventricular arrhythmia. J Hum Genet. 54(2): 115-121, 2009. (#; equal
contribution)
2. #Kominami
S, #Tanabe N, Ota M, Naruse T, Katsuyama
Y, Nakanishi N, Tomoike H, Sakuma M, Shirato K, Takahashi M, Shibata H, Yasunami M, Chen Z, Kasahara Y,
Tatsumi K, Kuriyama T, Kimura A. HLA-DPB1 and NFKBIL1 may confer the
susceptibility to chronic thromboembolic pulmonary hypertension in the absence
of deep vein thrombosis. J Hum Genet.
54(2): 108-114, 2009. (#; equal contribution)
1.
Arimura T, Hayashi YK, Murakami T, Oya Y, Funabe
S, Hirasawa EA, Hattori N, Nishino I, Kimura
A. Mutational analysis of fukutin gene in dilated
cardiomyopathy and hypertrophic cardiomyopathy. Circ J. 73(1): 158-161, 2009.
9.
Nakajima T, Kaur G, Mehra NK, Kimura
A. HIV-1/AIDS susceptibility and copy number variation in CCL3L1, a gene
encoding a natural ligand for HIV-1 co-receptor CCR5. Cytogenet Genome Res.
123(1-4): 156-160, 2008.
8. Nakajima
T, Ohtani H, Satta Y, Uno Y,
Akari H, Ishida T, Kimura A. Natural
selection in the TLR-related genes in the course of primate evolution. Immunogenetics 60(12):
727-735, 2008.
7. Nakajima
T, Kimura A. Genetic factors
which confer sensitivity to highly active antiretroviral therapy (HAART) in
HIV-infected subjects: implication of a benefit of an earlier initiation of
HAART in HIV therapy. Pharmacogenomics 9(9): 1347-1351, 2008.
6. #Takemoto Y, #Naruse TK, Namba K, Kitaichi N, Ota M,
Shindo Y, Mizuki N, Gul A, Madanat W, Shams H, Davatchi
F, Inoko H, Ohno S, Kimura A. Re-evaluation of heterogeneity in HLA-B*510101 associated
with Behçetfs disease. Tissue Antigens
72(4): 347-353, 2008. (#; equal contribution)
5. Kimura
A. Molecular etiology and pathogenesis of hereditary cardiomyopathy. Circ J. 72(Suppl
A): A38-A48, 2008.
4. Tsukamoto T, Dohki
S, Ueno T, Kawada M, Takeda A, Yasunami M, Naruse T, Kimura A, Takiguchi M, Matano T. Determination of a major
histocompatibility complex class I restricting simian immunodeficiency virus
Gag241-249 epitope. AIDS 22(8): 993-994, 2008.
3. Hinohara K, Nakajima T, Takahashi M, Hohda
S, Sasaoka T, Nakahara K, Chida K, Sawabe M, Arimura T, Sato A, Lee BS, Ban J, Yasunami M, Park
JE, Izumi T, Kimura A. Replication
of association between a chromosome 9p21 polymorphism with coronary artery
disease in Japanese and Korean populations. J Hum Genet. 53(4): 357-359,
2008.
2. Kato N, Miyata T, Tabara Y, Katsuya T,
Yanai K, Hanada H, Kamide K, Nakura J, Hohara K, Takeuchi F, Mano H, Yasunami M, Kimura A, Kita Y, Ueshima H, Nakamura T, Soma M, Hata A, Fujioka A, Kawano Y,
Nakao K, Sekine A, Yoshida T, Nakamura Y, Saruta T, Ogihara
T, Sugano S, Miki T, Tomoike H. High-density
association study and nomination of susceptibility genes for hypertension in
the Japanese national project. Hum Mol Genet. 17(4): 617-627,
2008.
1. Shichi
D, Matsumori A, Naruse TK, Inoko H, Kimura A. HLA-DP beta chain may confer the susceptibility to
hepatitis C virus-associated hypertrophic cardiomyopathy. Int J Immunogenet.
35(1): 37-43, 2008.
24. Arimura T, Hayashi T, Kimura A. Molecular Etiology of Idiopathic Cardiomyopathy. Acta Myologica 26(3): 153-158, 2007.
23. Nakano
N, Hori H, Abe M, Shibata H, Arimura T, Sasaoka T, Sawabe M, Chida K, Arai T, Nakahara K, Kubo T, Sugimoto K,
Katsuya T, Ogihara T, Doi Y, Izumi T, Kimura A. Interaction of BMP10 with Tcap may modulate the course of hypertensive cardiac
hypertrophy. Am
J Physiol Heart Card Physiol. 293(6):
H3396-H3403, 2007.
22. Nakajima
T, Ohtani H, Naruse T, Shibata H, Mimaya J, Terunuma
H, Kimura A. Copy number variations
of CCL3L1 and long-term prognosis of HIV-1 infection in asymptomatic
HIV-infected Japanese with hemophilia. Immunogenetics 59(10): 793-798, 2007.
21. Kuba
K, Zhang L, Imai Y, Arab S, Chen M, Maekawa Y, Leschnik
M, Leibbrabdt A, Makovic M,
Schwaighofer J, Beetz N, Musialek
R, Neely GG, Komnenoviv V, Kolm U, Metzler B, Ricci
R, Hara H, Meixner A, Nghiem M, Chen X, Dawood F, Wong KM, Sarao R Cukerman E, Kimura A,
Hein L, Thalhammer J, Liu PP, Penninger JM. Impaired heart contractility in
Apelin gene-deficient mice associated with aging and pressure overload. Circ Res. 101(4): e32-e42, 2007.
20. Nakamura K, Katayama Y, Kusano KF, Haraoka K, Tani Y, Nagase S, Morita H, Miura D, Fujimoto Y,
Furukawa T, Ueda K, Aizawa Y, Kimura A, Kurachi Y, Ohe T. Anti-KCNH2
Antibody-induced long QT syndrome –novel
acquired form of long QT syndrome-. J Am Coll Cardiol.
50(18): 1808-1809, 2007.
19. #Arimura T, #Matsumoto Y,
Okazaki O, Hayashi T, Takahashi M, Inagaki N, Hinohara K, Ashizawa
N, Yano K, Kimura A. Structural
analysis of obscurin gene in hypertrophic
cardiomyopathy. Biochem Biophys Res Commun. 362(2):
281-287, 2007. (#; equal contribution)
18.
Chen Z, Takahashi M, Naruse T, Nakajima T, Chen YW, Inoue Y, Ishilkawa
I, Iwai T, Kimura A. Synergistic contribution
of CD14 and HLA loci to the susceptibility to Buerger disease. Hum Genet.
122(3-4): 367-372, 2007.
17. Kano T, Mori T, Furudono
M, Tamura I, Ishikawa H, Watanabe H, Kikkawa E, Warita T, Kawada H, Onizuka M, Takahashi M, Maeda Y, Naruse T, Inoko
H, Kimura A. HLA may predict outcome
of primary recurrent spontaneous abortion treated with paternal lymphocyte
alloimmunization therapy. Am J Reprod Immunol.
58(4): 383-387, 2007.
16. Knöll
R, Postel R, Wang J, Kraetzner R, Hennecke G, Vacaru
AM, Vakeel P, Schubert C, Murthy K, Rana BK, Dieter K, Gudrun K, Schaefer K, Hayashi T, Holm T, Kimura A, Schork N, Toliat MR, Nuemberg P, Schultheiss P, Schaper W, Schaper J, Bos E,
Hertog JD, van Eeden F, Peters P, Hasenfuss G, Chien KR, Bakkers
J. Laminin alpha 4 and integrin-linked kinase mutations cause human
cardiomyopathy via simultaneous defects in cardiomyocytes and in endothelial
cells. Circulation 116(5): 515-525, 2007.
15. Aizawa
Y, Ueda K, Scornik
F, Cordeiro JM, Wu Y, Desai M, Guerchicoff A, Nagata
Y, Iesaka Y, Kimura
A, Hiraoka M, Anzelevitch C. A novel mutation in
KCNQ1 associated with a potent dominant negative effect as the basis for the
LQT1 form of the long QT syndrome. J Cardiovasc Electrophysiol. 18(9): 972-977, 2007.
14. Sakagami
T, Jinnai N, Nakajima T, Sekigawa T, Hasegawa T, Suzuki E, Inoue I, Gejyo F. ADAM33 polymorphisms are associated with aspirin-intolerant
asthma in the Japanese population. J Hum
Genet. 52(1):66-72, 2007.
13. Ben Yaou
R, Toutain A, Arimura T, Demay L, Massart C, Peccate C, Muchir A, Llense S, Deburgrave N, Leturcq F, Litim KE, Rahmoun-Chiali
N, Richard P, Babuty D, Recan-Budiartha
D. Multitissular involvement in a family with LMNA
and EMD mutations: Role of digenic mechanism? Neurology 68(22): 1883-1894,
2007.
12. Muchir A, Pavilidis P, Decostre V, Herron
AJ, Arimura T, Bonne G, Worman JJ.
Activation of MAPK pathways links LMNA mutations to cardiomyopathy in Emery-Dreifess muscular dystrophy. J Clin Invest. 117(5):
1282-1293, 2007.
11. Minehisa
Y, Watanabe H, Kosaka T, Kimura A,
Ito H. Successful outcome in a pregnant woman with isolated noncompaction of
the left ventricular myocardium. Intern Med. 46(6): 285-289, 2007.
10. Arimura
T, Hayashi T, Matsumoto Y, Shibata H, Hiroi S, Nakamura T, Inagaki N, Hinohara K, Takahashi M, Itoh-Satoh M,
Bonne G, Schwartz K, Kimura A.
Structural analysis of four and half LIM protein-2 in dilated cardiomyopathy. Biochem Biophys Res Commun. 357(1):
162-167, 2007.
9. Maehata Y,
Takamizawa S, Ozawa S, Izukuri K, Kato Y, Sato S, Lee
MC, Kimura A, Hata R. Type III
collagen is essential for growth acceleration of human osteoblastic cells by
ascorbic acid 2-phosphate, a long-acting vitamin C derivative. Matrix Biol. 26(5): 371-81, 2007.
8. Sugimori C, Yamazaki H, Feng X,
Mochizuki K, Kondo Y, Takami A, Chuhjo T, Kimura A, Teramura
M, Mizoguchi H, Omine M, Nakao S. Roles of DRB1*1501
and DRB1*1502 in the pathogenesis of aplastic anemia. Exp Hematol.
35(1): 13-20, 2007.
7. Ota M, Katsuyama
Y, Hamano H, Umemura T, Kimura A,
Yoshizawa K, Kiyosawa K, Fukushima H, Bahram S, Inoko H, Kawa S. Two critical genes (HLA-DRB1 and ABCF1) in
the HLA region are associated with the susceptibility to autoimmune
pancreatitis. Immunogenetics 59(1):
45-52, 2007.
6. Nouchi
T, Yasunami M, Mibu R,
Yasunaga S, Itoh-Satoh M, Takahashi M, Tanaka S, Kuwano H, Kimura A.
Somatic mutations leading to incomplete extinction of HLA class I were
associated with replication error phenotype-positive corlorectal
carcinoma. MHC 13(3): 187-197, 2007.
5. Yatsu K,
Mizuki N, Hirata N, Oka A, Ito N, Yamane T, Ogawa M, Shiwa T, TabaraY, Ohno S, Soma M, Hata A, Nakano K, Ueshima H, Ogiwara T, Tomoike H,
Miki T, Kimura A, Mano S, Kulski JK, Umemura S, Inoko H.
High-resolution mapping for essential hypertension using microsatellite markers. Hypertension
49(3): 446-452, 2007.
4.
Kimura A, Takahashi M, Choi BY,
Bae SW, Hohta S, Sasaoka T, Nakahara K, Chida K, Sawabe M, Naruse T,
Izumi T, Park JE. Lack of association between LTA and LGALS2 polymorphisms and
myocardial infarction in Japanese and Korean populations. Tissue Antigens 69(3):
265-269, 2007.
3. Yamamoto H, Kawada M, Tsukamoto T,
Takeda A, Igarashi H, Miyazawa M, Naruse
T, Yasunami
M, Kimura A, Matano T.
Vaccine-based long-term stable control of simian-human immunodeficiency virus
89.6PD replication in rhesus macaques. J Gen Virol. 88(Pt2):
652-659, 2007.
2. Takahashi-Tanaka Y, Yasunami M, Naruse T, Hinohara K, Matano T, Mori K, Miysazawa M, Honda
M, Yasutomi Y, Nagai Y, Kimura A.
Reference strand-mediated conformation analysis (RSCA)-based typing of multiple
alleles in the rhesus macaque MHC class I Mamu-A and Mamu-B loci. Electrophoresis 28(6): 918-924, 2007.
1. Aizawa
Y, Mitsuma W, Ikrar T,
Komura S, Hanawa H, Miyaima S, Miyoshi F, Kobayashi
Y, Chinushi M, Kimura
A, Hiraoka M, Aizawa Y. Human cardiac ryanodine receptor mutations in ion
channel disorders in Japan. Int J Cardiol. 116(2): 263-265, 2007.
8.
Shibata H, Yasunami M, Obuchi N, Takahashi M,
Kobayashi Y, Numano F, Kimura A. Direct determination of SNP haplotype of NFKBIL1 promoter
polymorphism by DNA conformation analysis and its application to association
study of chronic inflammatory diseases. Hum
Immunol. 67(4-5):363-373, 2006.
7. Takahashi
M, Yasunami M, Kubota S, Tamai H, Kimura A. HLA-DPB1*0202 is associated
with a predictor of good prognosis of Graves disease
in Japanese. Hum Immunol. 67(1-2):
47-52, 2006.
6. Inagaki
N, Hayashi T, Arimura T, Koga Y, Takahashi M, Shibata H,
Teraoka K, Chikamori T, Yamashina A, Kimura A. alpha B-crystallin mutation
in dilated cardiomyopathy. Biochem Biophys Res Commun. 342(2): 379-386, 2006.
5. Shiina
T, Ota M, Shimizu S, Katsuyama Y, Hashimoto N, Takasu
M, Anzai T, Kulski JK, Kikkawa E, Naruse T, Kimura N, Yanagiya
K, Watanabe A, Hosomichi K, Kohara S, Iwamoto C, Umehara Y, Meyer A, Wanner V, Sano K, Macquin C, Ikeo K, Tokunaga K, Gojobori T, Inoko H, Bahram S. Rapid evolution of major
histocompatibility complex class I genes in primates generates new disease
alleles in humans via hitchhiking diversity. Genetics 173(3):1555-1570, 2006.
4. Kimura A, Takahashi M, Shibata H, Kobayashi Y, Obuchi N, Ota M, Inoko
H, Numano F, Yasunami M.
Identification of HLA-linked susceptibility genes for Takayasu arteritis. In Immunobiology
of the Human MHC vol. II
(Hansen HA, Dupont B, eds.), pp325-329, IHWG Press, Seattle, 2006.
3. Yasunami M, Shibata H, Shao WS, Takahashi M, Hamaguchi K, Sakata T, Ota M, Inoko
H, Kimura A. Mapping of three
different IDDM-susceptibility loci within the HLA region. In Immunobiology
of the Human MHC vol. II
(Hansen HA, Dupont B, eds.), pp330-333, IHWG Press, Seattle, 2006.
2. Naruse TK, Ota M, Katsuyama Y, Kikkawa E,
Shichi D, Kimura A, Matsumori A, Sasayama S, Inoko H.
Susceptible gene mapping of hepatitis C virus positive cardiomyopathy within
the HLA region. In Immunobiology of the Human MHC
vol. II (Hansen HA, Dupont B,
eds.), pp351-354, IHWG Press, Seattle, 2006.
1. Takahashi M, Yasunami M, Tamai
H, Kimura A. HLA-A and DPB1 control
the susceptibility and production of thyroid stimulatory antibodies,
respectively, in Graves' disease. In Immunobiology of the Human
MHC vol. II
(Hansen HA, Dupont B, eds.), pp364-367, IHWG Press, Seattle, 2006.
9. Matsumoto
Y, Hayashi T, Inagaki N, Takahashi M, Hiroi S, Nakamura T, ArimuraT, Nakamura K, Ashizawa N, Yasunami M, Ohe
T, Yano K, Kimura A. Functional
analysis of titin/connectin N2-B mutations found in
cardiomyopathy. J Muscle Res Cell Motil.
26: 367-374, 2005.
8. Munkanta M,
Terunuma H, Takahashi
M, Hanabusa H, Miura T, Ikeda S, Sakai M, Fujii T, Takahashi Y, Oka S,
Matsuda J, Ishikawa M, Takashima Y, Mimaya J, Ito M, Kimura A, Yasumani M. HLA-B polymorphism in Japanese HIV-1infectedlong-term surviving
hemophiliacs. Viral Immunol. 18:
500-505, 2005.
7. Shichi
D, Kikkawa FE, Ota M, Katsuyama Y, Kimura A, Matsumori
A, Kulsky JK, Naruse
KT, Inoko H. The haplotype
block,NFKBIL1-ATP6V1G2-BAT1-MICB-MICA,within the class III-class I boundary
region of the human major histocompatibility complex may control susceptibility
to hepatitis C virus associated dilated cardiomyopathy. Tissue Antigens 66: 200-208, 2005.
6. Kubo T, Kitaoka H, Okawa M, Matsumura
Y, Hitomi N, Yamazaki N, Furuno T, Takata J, Nishinaga
M, Kimura A, Doi YL. Lifelong left
ventricular remodeling of hypertrophic cardiomyopathy caused by a founder
frameshift deletion mutation in the cardiac myosin-binding protein C gene. J Am Coll Cardiol. 46:
1737-1743, 2005
5. Mori K, Sugimoto C, Ohgimoto S, Nakayama EE, Shinoda T, Kusagasa
S, Takebe Y, Kano M, Matano T, Yuasa T, Kitagawa D, Miyazawa M, Takahashi Y, Yasunami M, Kimura A, Yamamoto N, Suzuki Y, Nagai Y. Influence of glycosylation
on the efficacy of an Env-based vaccine against SIVmac239 in a macaque AIDS
model. J Virol.
79: 10386-10389, 2005.
4. Nishizaki M, Fujii H, Sakurada H, Kimura A, Hiraoka M. Spontaneous T wave
alterans in a patient with Brugada
syndrome--responses to intravenous administration of class I antiarrhythmic
drug, glucose tolerance test, and atrial pacing. J
Cardiovasc Electrophysiol. 16: 217-220,
2005.
3. Noguchi Y, Yashima T, Hatanaka A, Uzawa M, Yasunami M, Kimura A, Kitamura K. A mutation in
WFS1 in a Japanese family with autosomal dominant low-frequency sensorineural
hearing loss. Acta Oto-Laryngologica
125: 1189-1194, 2005.
2. Aizawa
Y, Ueda K, Komura S, Washizuka T, Chinushi M, Inagaki N, Matsumoto Y, Hayashi T, Takahashi M, Nakano N, Yasunami M, Kimura A, Hiraoka M, Aizawa Y. A novel mutation in FKBP12.6 binding
region of the human cardiac ryanodine receptor gene (R2401H) in Japanese
patient with catecholaminergic polymorphic ventricular tachycardia. Int J Cardiol. 99(2): 343-345, 2005.
1. Tanabe N, Kimura A, Amano S, Okada O, Kasahara Y, Tatsumi K, Takahashi M, Shibata H, Yasunami M, Kuriyama T. Association of clinical
features with HLA in chronic pulmonary thromboembolism in Japan. Eur Resp J. 25(1): 131-138, 2005.
12. Hayashi
T, Arimura T, Itoh-Satoh M, Ueda K, Hohda
S, Inagaki, N, Takahashi M, Hori H, Yasunami M, Nishi H, Koga Y, Nakamura H,
Matsuzaki M, Cho BY, Bae SW, You CW, Han KH, Park JE, Knoll R, Hoshijima M, Chien KR, Kimura
A. TCAP mutations in hypertrophic cardiomyopathy and dilated
cardiomyopathy. J Am Coll Cardiol.
44: 2192-2201, 2004.
11. Sasano T, Ueda K, Orikabe M, Hirano Y, Kawano S, Yasunami M, Isobe M, Kimura A, Hiraoka M. Novel C-terminus frameshift mutation,
1122fs/147, of HERG in LQT2: additional amino acids generated by frameshift
cause accelerated inactivation. J Mol Cell Cardiol. 37: 1205-1211, 2004.
10. Aizawa
Y, Ueda K, Wu LM, Inagaki N, Hayashi T, Takahashi M,
Ohta M, Kawano S, Hirano Y, Yasunami M,
Aizawa Y, Kimura A, Hiraoka M.
Truncated KCNQ1mutant,A178fs/105, forms hetero-multimer channel with wild-type
causing a dominant-negative suppression due to trafficking. FEBS Lett. 574: 145-150, 2004.
9. Sasaki K, Makita N, Sunami A,
Sakurada H, Shirai N, Yokoi H, Kimura A,
Tohse N, Hiraoka M, Kitabatake
A. Unexpected mexiletine responses of a mutant cardiac Na+ channel implicate
the selectivity filter as a structural determinant of antiarrhythmic drug
access. Mol Pharmacol.
66: 330-336, 2004.
8. Hamaguchi K, Kimura A, Kusuda Y, Yamashita T, Yasunami M, Takahashi M, Abe N,
Yoshimatsu H. Clinical and genetic characteristics of GAD-antibody positive
patients initially diagnosed as having type 2 diabetes. Diabet Res
Clin Pract. 66: 163-171, 2004.
7. Ueda
K, Nakamura K, Hayashi T, Inagaki N, Takahashi M, Arimura T,
Morita H, Higashiuesata Y, Hirano Y, Yasunami M, Takishita
S, Yamashina A, Ohe T, Sunamori M, Hiraoka M, Kimura A. Functional characterization
of a trafficking-defective HCN4 mutation, D553N, associated with cardiac
arrhythmia. J Biol Chem. 279:
27194-27198, 2004.
6. Matano T, Kobayashi M, Igarashi H,
Takeda A, Nakamura H, Kano M, Sugimoto C, Mori K, Iida A, Hirata T, Hasegawa M,
Yuasa T, Miyazawa M, Takahashi Y, Yasunami M, Kimura A, O'Connor DH, Watkins DI,
Nagai Y. Cytotoxic T lymphocyte-based control of simian immunodeficiency virus
replication in a preclinical AIDS vaccine trial, J
Exp Med. 199: 1709-1718, 2004.
5. Komamura K, Iwai N, Kokame K, Yasumura Y, Kim J,
Yamagishi M, Morisaki T, Kimura A, Tomoike H, Kitakaze M, Miyatake
K. The role of a common TNNT2 polymorphism in cardiac hypertrophy. J Hum Genet. 49: 129-133, 2004.
4. Yamashita T, Hamaguchi K, Kusuda Y, Kimura A, Sakata T, Yoshimatsu H. IKBL
promoter polymorphism is strongly associated with resistance to type 1 diabetes
in Japanese. Tissue Antigens 63:
223-230, 2004.
3. Ogimoto A,
Hamada M, Nakura J, Shigematsu Y, Hara Y, Ohtsuka T,
Morishima A, Kimura A, Miki T, Hiwada K. 17-year follow-up study of a patient with
obstructive hypertrophic cardiomyopathy with a deletion mutation in the cardiac
myosin binding protein C gene. Circ J. 68:
174-177, 2004.
2. Arimura
T, Hayashi T, Terada H, Lee SY,
Zhou Q, Takahashi M, Ueda K, Nouchi T, Hohta S, Sibutani
M, Hirose M, Chen J, Park JE, Yasunami M,
Hayashi H, Kimura A. A Cypher/ZASP
mutation associated with dilated cardiomyopathy alters the binding affinity to
protein kinase C. J Biol Chem. 279:
6746-6752, 2004.
1.
Hayashi T, Arimura T, Ueda K, Shibata H, Hohda S, Takahashi M, Hori H,
Koga Y, Oka N, Imaizumi T, Yasunami M, Kimura A. Identification and functional
analysis of acaveolon-3 mutation associated with familial hypertrophic
cardiomyopathy. Biochem Biophys Res Commun. 313: 178-184, 2004.
7. Okamoto K, Makino S, Yoshikawa Y,
Takaki A, Nagatsuka Y, Ota M, Tamiya G, Kimura
A, Bahram S, Inoko H. Identification of IkBL as the second MHC-linked susceptibility locus for
Rheumatoid Arthritis. Am J Hum Genet. 72:
303-312, 2003.
6. Shao
W, Yasunami M, Takahashi M, Shibata H,
Hamaguchi K, Sakata T, Ota M, Katsuyama Y, Inoko H, Kimura A.
Analysis of HLA-B polymorphism in insulin dependent diabetes mellitus in
Japanese. MHC 9: 163-169, 2003.
5. Hohda S, Kimura A, Sasaoka T, Hayashi T, Ueda K, Yasunami M, Okabe M, Fukuda N, Kurosawa T, Izumi T. Association study of
the CD14 polymorphism with myocardial infarction in Japanese populations. Jpn Heart J. 44: 613-622, 2003.
4. Yoshida Y, Takano Y, Sasaoka T, Izumi T, Kimura A.
E-selectin polymorphism associated with myocardial infarction causes enhanced
leukocyte-endothelial interactions under physiological flow conditions. Arter Thrombo Vasc Biol. 23: 783-788, 2003.
3. Kimura
A, Hayashi T, Itoh-Satoh M, Arimura T, Lee WH, Lee SY, Park JE. Molecular etiology of
idiopathic cardiomyopathy: Identification of novel disease genes for
hypertrophic cardiomyopathy and dilated cardiomyopathy. In Cardiomyopathies and Heart Failure; Biomolecular,
Infectious and Immune Mechanisms (ed. Matsumori
A), pp415-428, Klumer Academic Publishers,
2. Kimura
A, Itoh-Satoh M, Hayashi T, Takahashi M, Arimura T, Yasunami M, Lee SY, Hwang TH, Lee WH, Park JE.
Mutational profiles and molecular pathogenesis of hypertrophic cardiomyopathy
and dilated cardiomyopathy in Asian populations. In Frontiers
in Cardiovascular Health (eds. Dhalla NS, Chockalingam A, Berkovitz
HI, Singal PK),pp195-206, Klumer Academic Publishers,
Boston, 2003.
1. Kurosaka D, Yoshida K, Yasuda J, Yokoyama
T, Kingetu I, Yamaguchi
N, Joh K, Matsushima M, Saito S, Yamada A. Arthritis-inhibiting effect of
systemic administration of endostatin in passive murine collagen-induced
arthritis. Ann Rheum Dis. 62:
677-679, 2003
13. Knoll R, Hoshijima
M, Hoffmann HM, Person V, Lorenzen-Schmidt I, Bang M-L, Hayashi T, Shiga N, Yasukawa H, Schaper W, McKenna W, Yokoyama M,
Schork J, Jeffrey H, Omens J, Andrew D, McCulloch A, Kimura A, Gregorio CC, Poller W, Schaper J, Schulthelss
HP, Chien KR. The cardiac mechanical stretch sensor machinery involves a Z disc
complex that is defective in a subset of human dilated cardiomyopathy. Cell 111: 943-955, 2002.
12.
Hori H, Hattori S, Inouye S, Kimura
A, Irie S, Miyazawa H, Sakaguchi M. Analysis of the major epitope of the
alpha 2 chain of bovine type I collagen in children with bovine gelatin allergy.
J Clin Allergy Clin Immunol. 110:652-658,
2002.
11. Matsumori A,
Furukawa Y, Hasegawa K, Sato Y, Nakagawa H, Morikawa Y, Miura K, Ohno Y, Inaba
Y, Sasayama S, Fujiwara H, Hiroe M, Hori M, Imaizumi T, Inoko
H, Izumi T, Kawai S, Kawana M, Kimura A,
Kitabatake A, Kitamura S, Kitaura
Y, Matsuzaki M, Nagai R, Ogawa S, Shimada T, Simotohno
K, Takeda N, Takihara K, Tanaka M, Tei T, Toyo-oka T, Yamaguchi I, Yokoyama M, Yutani C. Epidemiologic and
clinical characteristics of cardiomyopathies in Japan: Analysis by nationwide
surveys. Circ J. 66: 323-336, 2002.
10. Kuroda N, Ohnishi Y, Kimura A, Yokoyama M. Clinical significance of T-wave alternans in
hypertrophic cardiomyopathy. Circ J. 66:
457-462, 2002.
9. Harada
H, Kimura A, Fukino
K, Yasunaga S, Nishi H, Emi M. Genomic structure and eight novel exonic polymorphisms of the human N-cadherin gene. J@Hum Genet. 47: 330-332, 2002.
8. Shirai N, Makita N, Sasaki K, Yokoi H,
Sakuma I, Sakurada H, Akai J, Kimura A,
Hiraoka M, Kitabatake A. Implication of an
overlapping Na channelopathy in an idiopathic ventricular fibrillation
associated with a cardiac Na channel mutation. Cardiovasc
Res. 53: 348-354, 2002.
7. Satoh-Itoh
M, Hayashi T, Nishi H, Koga Y, Arimura T, Ueda K, Hohta S,
Nouchi T, Takahashi M, Hiroe M,
Marumo F, Imaizumi T, Yasunami M,
Kimura A. Titin mutations as the molecular basis for dilated
cardiomyopathy. Biochem Biophys Res Commun. 291: 385-393, 2002.
6. Sakaguchi M, Nakayama T, Kaku H, Taniguchi
K, Saito S, Kimura A, Inoue S.
Analysis of HLA in children with gelatin allergy. Tissue
Antigens 59: 412-416, 2002.
5. Nemoto T, Hori H, Yoshimoto M, Seyama Y, Kubota S.
Overexpression of ornithine decarboxylase enhances endothelial proliferation by
suppressing endostatin expression. Blood 15:1478-81,
2002.
4. Morimoto T, Aoyagi M, Tamaki M, Yoshino Y, Hori H, Duan L, Yano T, Shibata M, Ohno
K, Hirakawa K, Yamaguchi N.
Increased levels of tissue endostatin inhuman malignant gliomas. Clin Cancer Res. 8: 2933-2938, 2002.
3. Matsuno H, Yudoh
K, Uzuki M, Nakazawa F, Sawai T, Yamaguchi N, Olsen BR, Kimura T. Treatment with the angiogenesis
inhibitor endostatin: A novel therapy in rheumatoid arthritis. J Rheumatol. 29:
890-895, 2002.
2. Furumatsu T, Yamaguchi N, Nishida K, Kawai A,
Kunisada T, Namba M, Inoue H, Ninomiya Y. Endostatin inhibits adhesion of
endothelial cells to collagen IVIaż2Ŕ1 integrin, a possible cause of prevention of chondrosarcoma growth.
J Biochem (Tokyo). 131:619-26,
2002.
1. Akagi A, Tajima S, Ishibashi A, Matsubara
Y, Takehana M, Kobayashi S, Yamaguchi N. Type XVI collagen is expressed in factor XIIIa+ monocyte-derived dermal dendrocytes
and constitutes a potential substrate for factor XIIIa.
J Invest Dermatol. 118: 267-274,
2002.
13. Takahashi
M, Hashimoto H, Akizuki M, Sasazuki
T, Nishikimi N, Ouchi H, Kobayashi Y, Numano F, Kimura A.
Lack of association between the Met196Arg polymorphism in the TNFR2 gene and
autoimmune diseases accompanied by vasculitis including SLE in Japanese. Tissue Antigens 57: 66-69, 2001.
12. Lee WH, Hwang TH, Kimura A, Park SW, Satoh M,
Nishi H, Harada H, Toyama J, Park
JE. Different expressivity of a ventricular essential light chain gene Ala57Gly
mutation in familial hypertrophic cardiomyopathy. Am
Heart J. 141: 184-189, 2001.
11. Arimura T, Suematsu N, Zhou YB, Nishimura J, Satoh S, Takeshita A, Kanaide H, Kimura A.
Identification, characterization and functional analysis of heart-specific
myosin light chain phosphatase small subunit, J
Biol Chem. 276: 6073-6082, 2001.
10. Ota M, Katsuyama
Y, Kimura A, Tsuchiya K, Kondo M, Naruse T, Itoh K, Sasazuki
T, Inoko H. A second susceptibility gene for
developing rheumatoid arthritis in the human MHC is located within a 70 kb
interval telomeric of the TNF genes in the HLA class III region. Genomics 71: 263-270, 2001.
9. Soejima T,
Kawamoto S, Akai J, Miyoshi O, Arai Y, Morohka T,
Matsuo S, Niikawa N, Kimura A, Okubo K, Mukai T. Isolation of novel heart-specific
genes using the bodymap. Genomics
74: 115-120, 2001.
8. Kimura
A, Itoh-Satoh M, Hayashi T, Takahashi M, Arimura T.
Molecular etiology of idiopathic cardiomyopathy in Asian populations. J Cardiol. 37:
S139-S146, 2001.
7. Obuchi
N, Takahashi M, Nouchi T, Satoh M, Arimura T, Ueda K, Akai J, Ota M, Naruse T, Inoko H, Numano F, Kimura A.
Identification of MICA alleles with a long Leu-repeat in the transmembrane
region and no cytoplasmic tail due to a frameshift deletion in exon 4. Tissue Antigens 57: 520-535, 2001.
6. Kikuchi M, Looareesuwan
S, Ubalee R, Tasanor O,
Suzuki F, Wattanagoon Y, Na-Bangchang
K, Kimura A, Aikawa M, Hirayama K.
Association of adhesion molecule PECAM-1/CD31 polymorphism with susceptibility
to cerebral malaria in Thais. Parasitol Int. 50: 235-239, 2001.
5. Matsuzoe D, Hideshima T, Iwasaki A, Yoneda S, Kawahara K, Shirakusa T, Kimura
A. Glutathione S-transferase nu1 null genotype is associated with K-ras gene mutation in lung adenocarcinoma among smokers. Carcinogenesis 22: 1327-1330, 2001.
4. Sasaoka
T, Kimura A, Hohta S, Fukuda N, Kurosawa T, Izumi T. Polymorphisms in the
platelet-endothelial cell adhesion molecule-1 (PECAM-1) gene, Asn563Ser
andGly670Arg, are associated with myocardial infarction in Japanese. Ann NY Acad Sci. 947:
259-269, 2001
3. Fukuda Y, Hoshino S, Shintaku S, Tanaka I,
Dohi K, Kimura A. HLA-DMB
polymorphism in living-related kidney transplantation. Transpl
Proc. 33: 3302-3308, 2001.
2. Tsuchiya K, Kimura A, Kondo M, Nishimura Y, Sasazuki
T. Combination of HLA-A and HLA class II alleles controls the susceptibility to
rheumatoid arthritis. Tissue Antigens 58:
395-401, 2001.
1. Ubalee R, Suzuki
F, Kikuchi M, Tasanor O, Wattanagoon
Y, Ruangweerayut IIR, Na-Bangchang
K, Karbwang J,
Kimura A, Ito K, Kanda T, Hirayama K. Strong association of a tumor necrosis
factor-a promoter allele with cerebral malaria in Myanmar. Tissue Antigens 58: 407-410, 2001.
14. Kimura
A: Molecular genetic aspects of hypertrophic cardiomyopathy in the
Orientals. In The Hypertrophied Heart (Takeda
N, Nagano M,
13. Tajima S, Akagi A, Tanaka N, Ishibashi A,
Kawada A, Yamaguchi N: Expression of
type XVI collagen in cultured skin fibroblasts is related to cell growth
arrest. FEBS Lett. 469: 1-4, 2000.
12. Sakaguchi M, Toda M, Ebihara T, Irie S, Hori H, Imai A, Yanagida M, Miyazawa H,
Ohsuna H, Ikezawa Z, Inoue
S: IgE antibody to fish gelatin (type I collagen)in
patients with fish allergy. J Allergy Clin
Immunol. 106:579-584, 2000.
11. Oda H, Iwata I, Yasunami M, Ohkubo H: Structure of the mouse NDRF gene and its regulation
during neuronal differentiation of P19 cells. Mol.
Brain Res. 77: 37-46, 2000.
10. Arimura
T, Nakamura T, Hiroi S, Satoh M, Takahashi M, Ohbuchi N, Ueda K, Nouchi T, Yamaguchi N, Akai J, Matsumori A, Sasayama S, Kimura A: Characterization of human
nebulette gene: A polymorphism in an actin-binding
motif is associated with non-familial idiopathic dilated cardiomyopathy. Hum Genet 107: 440-451, 2000.
9. Akai
J, Kimura A, Hata R: Analysis of the topological
properties of the two dinucleotide repeat regions that enhance the
transcriptional activity of the human type 1 collagen collagena2 chain (COL1A2)gene
promoter. Connective Tissue 32: 259-265, 2000.
8. Aida K, Juarez S, Kikuchi M, Gil M, Ayau O,
DeLopez MP, Kaneko S, Yanagi T, Obispo T, Velasquez E, Jianbing M, Matta V, Paz
M, Kimura A, Itoh K, Tada I,
Hirayama K: HLA-B35 andMICA-A5 synergistically enhanced the susceptibility to
Chagas disease, Trypanozoma cruzi
infection. MHC 7: 63-70, 2000.
7. Akai
J, Makita N, Sakurada H, Shirai N, Ueda
K, Kitabatake A, Nakazawa K, Kimura A, Hiraoka M: A novel SCN5A mutation associated with
idiopathic ventricular fibrillation without typical ECG findings of Brugada syndrome. FEBS Lett.
479: 29-34, 2000.
6. Kimura
A, Ota M, Katsuyama Y, Ohbuchi N, Takahashi M,
Kobayashi Y, Inoko H, Numano
F: Mapping of the HLA-linked genes controlling the susceptibility to Takayasu's
arteritis. Int J Cardiol.
75: S105-S110, 2000.
5. Kamizono S, Hiromatsu Y, Seki N, Bednarczuk
T, Matsumoto H, Kimura A, Itoh K: A
polymorphism of the 5'flanking region of tumor necrosis factor alpha gene is
associated with thyroid-associated ophthalmopathy in Japanese. Clin Endocrinol. 52: 759-764, 2000.
4. Hata
R, Akai J, Kimura A, Ishikawa O, Kuwana M, Sinkai H: Association of functional
microsatellites in the human type 1 collagen a2 chain (COL1A2) gene with
systemic screlosis. Biochem Biophys Res Commun. 272:36-40,
2000.
3. Kamizono S,
Yamada K, Seki N, Higuchi T, Kimura A,
Nonaka K, Itoh K: Susceptible locus for obese type2 diabetes mellitus in the
5'-flanking region of the tumor necrosis factor-alpha gene. Tissue Antigens 55: 449-452, 2000.
2. Furuse M, Kimura A, Esaki M, Jo Y, Matsumoto T, Fujishima M: Polymorphism of
the heat-shock protein gene HSP70-2 in ulcerative colitis. MHC 7:2-6, 2000.
1. Hamaguchi K, Kimura A, Seki N, Higuchi T, Yasunaga S, Takahashi M, Sasazuki T, Kusuda Y, Okeda T,
Itoh K, Sakata T: Analysis of tumor necrosis factor-a promoter polymorphism in
type 1 diabetes: HLA-B and -DRB1 alleles are primarily associated with the
disease in Japanese. Tissue Antigens 55:
10-15, 2000.
19. Matsuzoe D, Hideshima T, Kimura
A, Inada K, Watanabe K, Akita Y, Kawahara K, Shirakusa
T: p53 mutations predict non-small cell lung carcinoma response to
radiotherapy. Cancer Lett. 135:
189-194, 1999.
18. Takahashi
M, Kobayashi Y, Ichiki M, Ouchi H, Numano F, Kimura A:HLA-linked susceptibility and resistance
to Buerger's disease in Japanese. MHC 5:7-12,
1999.
17. Matsuzoe D, Hideshima T, Ohshima K, Kawahara K, Shirakusa
T, Kimura A: Discrimination of
double primary lung cancer from intrapulmonary metastasis byp53 gene mutation. Br J Cancer. 79: 1549-1552, 1999.
16. Yoshitake S, Kimura A, Okada M, Yao T, Sasazuki T: HLA
class II alleles in Japanese patients with inflammatory bowel disease. Tissue Antigens 53: 350-358, 1999.
15. Fukuma K, Marubayashi S, Okuda K, Yamada K, Kimura A, Dohi K: Effect of lazaroid
U-74389G and methyl predonisolone on
endotoxin-induced shock in mice. Surgery
125: 421-430, 1999.
14. Doi YL, Kitaoka H, Hitomi N, Satoh M, Kimura A: Clinical expression in patients with hypertrophic
cardiomyopathy caused by cardiac myosin-binding protein C gene mutation. Circulation 100: 448-449, 1999.
13. Hiroi
S, Harada H, Nishi H, Satoh M, Nagai R, Kimura A: Polymorphisms in the SOD2 and HLA-DRB1
genes are associated with non-familial idiopathic dilated cardiomyopathy in
Japanese. Biochem Biophys Res Commun. 261: 332-339, 1999.
12.
Satoh M, Takahashi M, Sakamoto
T, Hiroe M, Marumo F, Kimura A:
Structural analysis of the titin gene in hypertrophic cardiomyopathy:
Identification of a novel disease gene. Biochem Biophys Res Commun. 262:
411-417, 1999.
11. Yoshitake S, Okada M, Kimura A, Sasazuki T: Contribution of
major histocompatibility complex genes to susceptibility and resistance in Helicobactor Pyroli
related diseases. Eur J Gastroenterol Hepatol. 11: 875-880, 1999.
10. Seki N, Kamizono
S, Yamada A, Matsumoto H, Niiya F, Kimura A, Tsuchiya K, Suzuki R, Date Y, Tomita T, Itoh K, Ochi T:
Polymorphisms in the 5'-flanking region of tumor necrosis factor-alpha gene in
patients with rheumatoid arthritis. Tissue
Antigens 54: 194-197, 1999.
9. Akai
J, Kimura A, Hata R: Tanscriptional
regulation of the human type I collagen a2 (COL1A2) gene by the
combination of two dinucleotide repeats. Gene 239:
65-73, 1999.
8. Djoulah S, Busson
M, Sasazuki T, Maillere B,
Yasunaga S, Kimura A, Charron D, Hors
J: A new predictive model for insulin-dependent diabetes mellitus
susceptibility based on combinations of molecular HLA-DRB1 andHLA-DQB1 pockets.
Tissue Antigens 54: 341-148, 1999.
7. Date
Y, Seki N, Kamizono S, Higuchi T, Miyata K, Ohkuni M, Tatsuzawa O, Yokota S,
Joo K, Ueda K, Joo K, Kimura A, Itoh
K, Kato H: Identification of genetic risk factor for systemic rheumatoid
arthritis in the 5'-flanking region of the TNF-alpha gene and HLA genes. Arthr Rheumat. 42:
2577-2582, 1999
6. Wang LM, Kimura A, Satoh M, Mineshita S: HLA
linked with leprosy in Southern China: HLA-linked resistance alleles to
leprosy. Int J Lepr. 67:
403-408, 1999.
5. Sakaguchi M, Hori H, Ebihara T., Irie S, Yanagida M, Inouye S: Reactivity of the
IgE in bovine gelatin-sensitive children to gelatins
from various animals. Immunology 96:
286-290, 1999.
4. Sakaguchi M, Hori H, Hattori S, Irie S, Imai A, Yanagida M, Miyazawa H, Toda M,
Inouye S: IgE reactivity to alpha1 and alpha2 chains
of denatured bovine type I collagen in children with bovine gelatin allergy. J Allergy Clin Immunol. 104: 695-699, 1999.
3. Akagi A, Tajima S, Ishibashi A, Yamaguchi N, Nagai Y: Expression of
type XVI collagen in human skin fibroblasts: enhanced expression in fibrotic
skin diseases. J Invest Dermatol. 113:
246-250, 1999.
2. Yamaguchi
N, Iwata S, Munakata Y, Ikushima H, Lee J F,
Hosono O, Schlossman SF, Morimoto C: CD26/dipeptidyl peptidase IV
differentially regulates the chemotaxis of T cells and monocytes toward RANTES:
possible mechanism for the switch from innate to acquired immune response. Int Immunol. 11: 417-426, 1999.
1. Yamaguchi
N, Anand-Apte B, Lee M. Sasaki T, Fukai N, Shapiro R, Que I, LowikC, Timpl R, Olsen B R:
Endostatin inhibits VEGF-induced endothelial cell migration and tumor growth
independently of zinc binding. EMBO J. 18:
4414-4423, 1999.
14. Ikeda M, Orimo
H, Moriyama H, Yoshitaka T, Matsubara N, Mibu R,
Tanaka N, Shimada T, Kimura A,
Shimizu K: Close correlation between mutations of E2F4 and hMSH3 genes in
colorectal cancers with microsatellite instability. Cancer
Res. 58:594-598, 1998.
13. Zeki K, Tanaka Y, Morimoto I, Nishimura Y,
Kimura A, Yamashita U, Eto S:
Induction of expression of MHC-class-II antigen on human thyroid carcinoma by
wild-type p53. Int J Cancer 75:
391-395, 1998.
12. Akai
J, Kimura A, Arai K, Uehara K, Hata R: Fine structural analysis of the
unique 5' region of human COL1A2 gene containing two regions of di-nucleotide
repeats adjacent to the transcriptional start site. Connective
Tissue 30: 1-6, 1998.
11. Shirai T, Hattori S, Sakaguchi M, Inoue S, Kimura A, Ebihara T, Irie S, Nagai R, Hori H: The complete cDNA coding
sequence for the bovine pro alpha 2(I) chain of type I procollagen. Matrix Biol. 17: 85-88, 1998.
10. Higuchi T, Seki N, Kamizono
S, Yamada A, Kimura A, Kato H, Itoh
K: Polymorphism of the 5'-flankingregion of human tumor necrosis factor
(TNF)-alpha gene in Japanese. Tissue Antigens 51:
605-612, 1998.
9. Hata
R, Akai J, Kimura A: Cell position dependent reciprocal feedback regulation of
type I collagen gene expression in cultured human skin fibroblasts. Cell Biol Internat. 22:
85-191, 1998.
8. Kimura
A, Kobayashi Y, Takahashi M, Ohbuhi N, Kitamura H, Satoh M, Nakamura T, Sasaoka T, Hiroi S, Aerbajinai W, Yasukochi Y, Numano F: MICA gene polymorphism in Takayasu arteritis and
Buerger disease. Int J Cardiol.
66: S107-S113, 1998.
7. Kitamura H, Kobayashi Y, Kimura A, Numano
F: Association of clinical manifestations with HLA-B alleles in Takayasu
arteritis. Int J Cardiol.
66: S121-S126, 1998
6. Matsumori A,
Ohashi N, Sasayama S, Eto T, Fujisawa H, Imaizumi T, Izumi T, Kawamura K,
Kawana M, Kimura A, Kitabatake A, Matsuzaki M, Nagai R, Tanaka H, Hiroe M, Hori
M, Inoko H, Seko Y, Sekiguchi M, Shimotohno
T, Sugishita Y, Takeda N, Takihara
K, Tanaka M, Tokuhisa T, Toyooka T, Yokoyama M:
Hepatitis C virus infection and cardiomyopathies: A multicenter study in Japan.
Jpn Circ J. 62: 389-391, 1998.
5. Sasazuki T, Juji
T, Morishima Y, Kinukawa N, Kashiwabara H, Inoko H, Yoshida T, Kimura
A, Akaza T, Kamikawaji N, Kodera Y, Takaku F:
Effect of matching of class I HLA alleles on clinical outcome after
transplantation of hematopoietic stem cells from an unrelated donor. N Engl J Med. 339:1177-1185, 1998.
4. Hwang T, Lee W, Kimura A, Satoh M, Nakamura T, Kim M, Choi S, Park J:
Early expression of a malignant phenotype of familial hypertrophic
cardiomyopathy associated with a Gly716Arg myosin heavy chain mutation in a
Korean family. Am J Cardiol.
82: 1509-1513, 1998.
3. Kai H, Muraishi
A, Sugiu Y, Nishi H, Seki Y, Kuwahara F, Kimura A, Kato H, Imaizumi T:
Expression of proto-oncogenes and gene mutation of sarcomeric
proteins in patients with hypertrophic cardiomyopathy. Circ Res. 83: 594-601, 1998.
2. Nomura Y, Kitteringham
N, Shia K, Goseki M, Kimura A, Mineshita S: Use of the highly
sensitive PCR method to detect the herpes Simplex Virus type 1genome from Behchet disease patients. J
Med Dent Sci. 45: 51-58, 1998.
1. Hata
RFInsoluble extracellular
matrix gives positional information to cells and regulates morphogenesis as a morphocreator. Connective
Tissue 30: 285-289, 1998.
21. Kimura
A, Harada H, Park J, Nishi H, Satoh M, Takahashi M, Hiroi S, Sasaoka T, Ohbuchi N, Nakamura T, Koyanagi
T, Hwang T, Choo J, Chung K, Hasegawa A, Nagai R, Okazaki O, Nakamura H,
Matsuzaki M, Sakamoto T, Toshima H, Koga Y, Imaizumi T, Sasazuki
T: Mutations in the cardiac troponin I gene associated with hypertrophic
cardiomyopathy. Nature Genet. 16:
379-382, 1997.
20. Kimura
A: Molecular genetics of hypertrophic cardiomyopathy in Japan. Internal Me.d 36:
152-154, 1997.
19. Macaubas C, Jin L, Hallmeyer J, Kimura A, Mignot E: The complex
mutation pattern of a microsatellite. Genome
Res. 7: 635-641, 1997.
18. Mignot E, Kimura A, Latterman A, Lin X, Yasunaga S,
Rattazzi C, Jin L, Guilleminault
C, Grumet FC, Dement WC, Underhill P: Extensive HLA class II studies in 58 non
DRB1*15 (DR2) narcoleptic patients with cataplexy maps susceptibility to the
coding region of DQA1*0102 and DQB1*0602 gene. Tissue
Antigens 49: 329-341, 1997.
17. Munkhbat B, Sato T, Hagihara M, Tsuchida
F, Sato K, Kimura A, Munkhtuvshin N, Tsuji K: Molecular analysis of HLA
polymorphism in Khoton-Mongolians. Tissue Antigens 50: 124-134, 1997.
16. Ohdan H, Fukuda
Y, Shintaku S, Miyata Y, Tashiro H, Hoshino S, Sumimoto
R, Asahara T, Kimura A, Dohi K:
Prolongation of hamster-to-rat liver xenograft survival by donor bone marrow
augmentation. Transplant Proc. 29:
925-927, 1997.
15. Tashiro H, Fukuda Y, Kimura A, Hoshino S, Shintaku S, Ohdan H,
Miyata H, Dohi K: Induction of donor-specific hyporeactivity
in augmented microchimerism in rat liver
transplantation followed by donor bone marrow. Transplant
Proc. 29: 1196-1197, 1997.
14. Tashiro H, Fukuda Y, Kimura A, Hoshino S, Furukawa M, Shintaku S, Dohi K: Correlation
of high-level microchimerism with graft acceptance in
rat liver transplantation. Transplant Proc. 29:
1230-1231, 1997.
13. Lin L, Jin L, Kimura A, Carrington M, Mignot E: DQ
microsatellite association studies in three ethnic groups. Tissue Antigens 50: 507-520, 1997.
12. Ohsuzu F,
Katsushika S, Akanuma M, Nakamura H, Harada H, Satoh M, Hiroi S, Kimura A: Hypertrophic obstructive
cardiomyopathy due to a novel T-to-A transition at codon 624 in the b-myosin heavy chain (beta-MHC) gene possibly
related to the sudden death. Int J Cardiol. 62: 203-209, 1997.
11. Tamamori M, Ito
H, Hiroe M, Marumo F, Hata R: Stimulation
of collagen synthesis in rat cardiac fibroblasts by exposure to hypoxic culture
conditions and suppression of the effect by natriuretic peptides. Cell Biol Int. 21: 175-180, 1997.
10. Fukuda K, Hori H, Utani A, Burbelo
P, Yamada Y: Formation of recombinant triple-helical [alpha1(IV)]2alpha2(IV)
collagen molecules in CHO cells. Biochem Biophys Res Commun. 231:178-182, 1997.
9. Saito F, Yamada H, Sunada Y, Hori H, Shimizu T, Matsumura K:
Characterization of a 30 kDa peripheral nerve
glycoprotein that binds laminin and heparin. J
Biol Chem. 272: 26708-26713, 1997.
8. Mimata C, Kitaoka M, Nagahiro
S, Iyama K, Hori
H, Yoshioka H, Ushio Y: Differential distribution and expressions of
collagens in the cerebral aneurysmal wall. Acta Neuropathol. 94: 197-206, 1997.
7. Bencova M, Benca
J, Kimura A, Podoba J: Hashimoto's
thyroiditis and HLA-DR/DQ haplotypes associated with control of disease
resistance. In Immunogenetics: Advances
and Education (Madrigal AJ, Bencova M, Middleton D, Charron D eds.), pp99-101, Kulwer Academic Publishers, Dordrecht,1997.
6. Bencova M, Kimura A, Yoshida M, Hoshino S, Porubska S, Buc M, Reznicek J, Sasazuki
T: The role of HLA-DR, DQ, DP subregions compatibility in the induction of
cytotoxic T lymphocytes in kidney transplantation from living donor. In Immunogenetics: Advances and Education (Madrigal
AJ, Bencova M, Middleton D, Charron D eds.),
pp153-158, Kulwer Academic Publishers,
Dordrecht,1997.
5. Kimura
A, Date Y, Yasunaga S, Sasazuki T: DNA typing of the HLA-A gene and its clinical
application. In Genetic Diversity of HLA:
Functional and Medical Implications, vol. II
(Charron D ed.), pp330-332, EDK Press,
4. Yasunaga S, Kimura A, Sasazuki T: Comprehensive
sequence analysis ofHLA-DQA1 and -DQB1 alleles and characterization of
DRB-QAP-DQA1-DQB1 haplotypes. In Genetic
Diversity of HLA: Functional and Medical Implications, vol. II (Charron D ed.), pp113-114, EDK Press,
3. Mignot E, Macaubas
C, Jin L, Hallmayer J, Kimura A, Grumet FC: The natural
history of a microsatellite located in the HLA-DQ region. In Genetic Diversity of HLA: Functional and Medical
Implications, vol. II (Charron D ed.),
pp121-124, EDK Press,
2. Hirayama K, Sulaiman LH, Kimura A, Joo OK, Kikuchi M, Samah MZA,
Abdullah NH, Kojima S, Wah MJ: Anti-malarial HLA-B53 in Africa and common DNA
type HLA-B*1513 in Malaysian aborigines share a C-terminal pocket of peptide
binding groove. In Genetic Diversity of
HLA: Functional and Medical Implications, vol. II (Charron D ed.), pp689-692, EDK Press,
1. Kojima N, Miura M, Matano Y, Imai K, Sato
M, Senoo H, Hata R: Reversible
regulation of hepatic stellate cell functions by three-dimensional structure of
extracellular matrix. In Cells of the
Hepatic Sinusoid, Vol.6 (Wisse E,
Knook D L, Balabaud C, eds),107-109,Kupffer Cell
Foundation, Leiden, 1997.
25. Yasunaga S, Kimura A, Hamaguchi K, Roenningen KS, Sasazuki T: Different contribution of HLA-DR and -DQ genes
in susceptibility and resistance to insulin-dependent diabetes mellitus (IDDM).
Tissue Antigens 47: 37-48, 1996.
24. Date
Y, Kimura A, Kato Y, Sasazuki T: DNA typing of HLA-A gene: population study and
identification of four new alleles in Japanese. Tissue
Antigens 47: 93-101, 1996.
23. Tashiro H, Fukuda Y, Kimura A, Hoshino S, Ito H, Dohi K: Assessment of microchimerism in rat liver transplantation by polymerase
chain reaction. Hepatology 23:
828-834, 1996.
22. Tamai H, Sudo T, Kimura A, Matsubayashi S, Kuma K, Nagataki
S: Association between the DRB1*08032 histocompatibility antigen and
methimazole-induced agranulocytosis in Japanese patients with Graves disease. Ann Internal
Med. 124:490-494, 1996.
21. Kimura
A, Kitamura H, Date Y, Numano F: Comprehensive analysis of HLA genes in Takayasu
arteritis in Japan. Int J Cardiol.
54: S65-S73, 1996.
20. Aerbajinai W,
Tsuchiya T, Kimura A, Yasukochi Y, Numano F: HLA class IIDNA typing in Buerger's disease. Int J Cardiol. 54:
S197-S202, 1996.
19. Hori T, Kamikawaji N, Kimura A, Sone T, Komiyama N, Komiyama S, Sasazuki
T: Japanese ceder polinosis
and HLA-DP5. Tissue Antigens 47:
485-491, 1996.
18. Koyanagi T, Koga Y, Nishi H, Toshima H, Sasazuki T, Imaizumi T, Kimura A: DNA typing of HLA class II genes in Japanese patients
with rheumatic heart disease. J Mol Cell Cardiol. 28: 1349-1353, 1996.
17. Fukuda Y, Kimura A, Hoshino S, Shintaku S, Sakaguchi T, Asahara T, Sakaki M, Sumimoto R, Tashiro H, Furukawa M, Ohdan
H, Yoshida T, Dohi K: HLA-DR8 subtyping by polymerase chain reaction(PCR)- DNA
conformation polymorphism(DCP) analysis: a simple and practical genotyping
method. Hiroshima J Med Sci. 45:
85-92, 1996.
16. Muto M, Date Y, Ichimiya M, Mori K, Kamikawaji N,
Kimura A, Sasazuki
T, Asagami C: Significance of antibodies to
streptococcal M protein in psoriatic arthritis and their association with
HLA-A*0207. Tissue Antigens 48:
645-650, 1996.
15. Hirayama K, Samah MZA, Sulaiman LH, Kimura A, Joo OK, Kikuchi M, Abdullah
NH, Kojima S, Wah MJ: Molecular analysis of HLA-B in the Malaysian aborigines. Tissue Antigens 48: 692-697, 1996.
14. Jin L, Macaubas C, Hallmayer J, Kimura A, Mignot E: Mutation rate
varies among alleles at a microsatellite locus: phylogenic evidence. Proc Natl Acad Sci
13. Koga Y, Toshima H, Kimura A, Harada H,
Koyanagi T, Nishi H, Nakata M, Imaizumi T: Clinical manifestations of
hypertrophic cardiomyopathy with mutations in the cardiac b-myosin heavy chain and cardiac troponin T
genes. J Cardiac Failure 2: S97-S103,
1996.
12. Mori K, Sasazuki
T, Kimura A, Ito Y: HLA-DP antigens
and poststrreptococcal acute glomerulonephritis in
Japan. Acta Paediatrica
85: 916-918, 1996.
11. Shintaku S, Fukuda Y, Kimura A, Hoshino S, Asahara T, Dohi K: HLA-A and-B@genotyping in living related one haploidentical
kidney transplantation. Jpn J Med Sci Biol. 49: 187-200, 1996.
10. Maruya E,
Ishikawa Y, Lin L, Tokunaga K, Kimura A,
Nita H, Yokoyama S, Saji H: Allele typing of HLA-A10 group by nested-PCR-low
ionic strength single strand conformation polymorphism and a novel A26 allele
(A26KY, A*2605). Hum Immunol. 50:
140-147, 1996.
9. Senoo H, Imai K, Sato M, Kojima N, Miura M,
Hata R: Three-dimensional structure
of extracellular matrix reversibly regulates morphology, proliferation and
collagen metabolism of perisinusoidal stellate cells. Cell Biol Int. 20: 501-512, 1996.
8. Sasaki T, Hori H, Arai K, Hattori S, Nagai Y: Effects of a factor derived from
polymorphonuclear leukocytes on the growth and collagen metabolism in normal
and scleroderma skin fibroblast cultures. J
Dermatol Sci. 11: 10-18, 1996.
7. Yamada H, Chiba A, Endo T, Kobata A,
Anderson LVB, Hori H, Fukuta-Ohi H, Kanazawa I, Campbell KP, Shimizu T, Matsumura
K: Characterization of dystroglycan-laminin
interaction in peripheral nerve. J Neurochem. 66: 1518-1524, 1996.
6. Kobayashi T, Onoda N, Takagi T, Hori H, Hattori S, Nagai Y, TajimaS, Nishikawa T: Immunolocalizations of human gelatinase
(type IV collagenase, MMP9)and TIMP (tissue inhibitor of metalloproteinases) in
normal epidermis and some epidermal tumors. Arch
Dermatol Res. 288: 239-244, 1996.
5. Yamada H, Denzer AJ, Hori H, Tanaka T, Anderson LVB, Fujita S, Fukuta-Ohi
H, Shimizu T, Ruegg MA, Matsumura K: Dystroglycan is
a dual receptor for agrinandlaminin-2 in Schwann cell membrane. J Biol Chem. 271:23418-23423, 1996.
4. Kobayashi T, Sakuraoka
T, Hattori S, Hori H, Nagai Y,
Tajima S, NishikawaT: Immunolocalization of human
gelatinase (type IV collagenase, MMP-9) and tissue inhibitor of
metalloproteinase 1 in Hailey-Hailey and Darier's diseases. Dermatol. 193: 110-114, 1996.
3. Kitaoka M, Iyama
K, Ushijima T, Mimata C, Hori H, Abe
N, Yoshioka H: Differential expressions of collagen types IV, III, and I during
the development of invasive trophoblasts in rats. Dev
Dynamics 207: 319-331,1996.
2. Mizuta T, Shimada H, Arai K, Hori H, Hattori S, Yamamoto K, Sakai T,
Nagai Y: Characterization of monoclonal antibodies recognizing human merosin and their use in affinity purificaion
of native merosin. Hybridoma
15: 373-378, 1996.
1. Jin L, Macaubas C, Hallmayer J, Kimura A, Mignot E: Tracking the
evolutionary history of a microsatellite locus located in the
HLA-DQA1/DQB1class II region: a phylogenic approach. In Current Topics on Molecular Evolution (Nei M,
Takahata N eds.), pp79-87,
19.
Kimura A, Nishi H, Harada H, Noguchi
M, Ashizawa N, Koga Y, Yano K, Yazaki Y, Kitabatake A, Toshima H, Sasazuki
T. Genetic analysis of hypertrophic cardiomyopathy in Japan. In Developmental Mechanisms of Heart Disease (Clark
EB, Markwald RR, Takao A eds.) pp113-120, Futura
Press, New York, 1995.
18. Kimura
A, Harada H, Nishi H, Yasunaga
S, Koyanagi T, Koga Y, Imaizumi T, Toshima H, Sasazuki
T. Genetic approaches to identification of a novel responsible gene for
hypertrophic cardiomyopathy. In Cardiac
Development and Gene Regulation (Yazaki Y ed.), pp127-144, Excerpta
Medica, Tokyo, 1995.
17. Ohsako N, Tamai
H, Sudo T, Mukuta T, Tanaka H, Kuma K, Kimura
A, Sasazuki T. Clinical characteristics of
subacute thyroiditis classified according to Human Leukocyte Antigen typing. J Clin Endocrionol Metab. 80:
3653-3656, 1995.
16. Nakajima A, Matsuhashi N, Kodama T, Yazaki
Y, Takazoe M, Kimura
A. HLA-linked disease susceptibility gene and disease resistance gene in
Crohn's disease. Gastroenterol. 109: 1462-1467, 1995.
15. Mignot E, Kimura A, Abbal M, Thorsby E, Lin X, Voros A, Macaubas
C, Bouissou F, Sollid LM, Cambon-Thomsen A, Yasunaga
S, Grumet FC. DQCAR microsatellite polymorphisms in three selected HLA Class II
associated diseases. Tissue Antigens 46: 299-304, 1995.
14. Haas JP, Kimura A, Truckenbrodt H, Suschke J, Sasazuki T, Volgger A, Albert ED. Early-onset pauciarticular
juvenile chronic arthritis is associated with a mutation in the Y-box of the
HLA-DQA1 promoter. Tissue Antigens 45: 317-321, 1995.
13. Sudo T, Kamikawaji N, Kimura A, Date Y, Savoie
CJ, Nakashima H, Furuichi E, Kuhara S, Sasazuki T.
Differences in MHC-class I self-peptide repertoires among HLA-A2 subtypes. J Immunol.
155: 4749-4756, 1995.
12. Nakao M, Yamana H, Imai Y, Toh Y, Toh U, Kimura A, Yanoma
S, Kakegawa T, Itoh K. HLA A2601-restricted cytotoxic
T lymphocytes recognizing a peptide antigen expressed on squamous cell
carcinoma. Cancer
Res. 55: 4248-4252, 1995.
11. Nishi H, Koga Y, Koyanagi T, Harada H, Imaizumi T, Toshima H, Sasazuki T, Kimura A.
DNA typing of HLA class II genes in Japanese patients with dilated
cardiomyopathy. J
Mol Cell Cardiol. 27: 2385-2392, 1995.
10. Nishi H, Kimura A, Harada H, Koga
Y, Adachi K, Matsuyama K, Koyanagi T, Imaizumi T, Toshima H, Sasazuki T. A myosin missense mutation, not a null allele,
causes familial hypertrophic cardiomyopathy. Circulation 91: 2911-2915, 1995.
9. Petronzelli F, Kimura A, Ferrante P, Mazzilli MC.
Polymorphism in the upstream regulatory region of DQA1 gene in the Italian
population. Tissue
Antigens 45: 258-263, 1995.
8. Kato M, Takazawa
K, Kimura A, Rüegg
JC, Amano K, Wang Y, Sasaki Y, Toyo-oka T. Altered
actin binding with myosin mutation in hypertrophic cardiomyopathy and sudden
death. Lancet
345: 1247, 1995.
7. Mukai T, Kimura A, Ishibashi H, Sasazuki T, Sata
M, Maruyama T, Sakai H, Niho Y. Association of
HLA-DRB1*0803 and *1602 with the susceptibility to primary biliary cirrhosis. Intrenat Hepatol Commun. 3: 207-212, 1995.
6. Dong RP, Kamikawaji N, Toida
N, Fujita Y, Kimura A, Sasazuki T. Characterization
of T cell epitopes in streptococcal M12 protein restricted by HLA-DP9. J Immunol.
154: 4536-4545, 1995.
5. Fukuda Y, Kimura A, Hoshino S, Tashiro H, Furukawa M, Shintaku S, Hori H, Sasazuki T, Dohi K. Significance of the HLA-DQB1 matching
in one-haplotype identical kidney transplant pairs and the matching analysis by
the polymerase chain reaction (PCR)-heteroduplex-polymorphism method. Tissue Antigens
45: 49-56, 1995.
4. Macaubas C, Hallmayer J, Kalil J, Kimura
A, Yasunaga S, Grumet FC, Mignot E. Extensive polymorphism of a (CA)n
microsatellite located in the HLA-DQA1/DQB1 class II region. Hum Immunol.
42: 209-220, 1995.
3. Wan XL, Kimura A, Dong RP, Honda K, Tamai
H, Sasazuki T. HLA-A and DRB4 genes in controlling
the susceptibility to Hashimoto's thyroiditis. Hum Immunol. 42: 131-136, 1995.
2. Shintaku S, Kimura A, Fukuda Y, Date Y, Tashiro H, Hoshino S, Furukawa M, Sasazuki T, Dohi K. Polymerase chain reaction-based HLA-A
genotyping and its application to matching in kidney transplantation. Transpl Proc.
27: 689-692, 1995.
1. Tashiro H, Fukuda Y, Kimura A, Hoshino S, Furukawa M, Shintaku S, Dohi K. Monitoring for
engraftment of rat orthotopic liver transplantation by semiquantitative PCR. Transpl Proc.
27: 537-539, 1995.