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Medical Research Institute Tokyo Medical and Dental University

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A sublethal ATP11A mutation associated with neurological deterioration causes aberrant phosphatidylcholine flipping in plasma membranes
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Integrative genome-wide analyses reveal the transcriptional aberrations in Japanese esophageal squamous cell carcinoma
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miR-766-5p targets super-enhancers by downregulating CBP and BRD4
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19th Surugadai International Symposium & Joint Usage/Research Program of Medical Research Institute International Symposium(2021.9.3)
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Hepta-Histidine Inhibits Tau Aggregation
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Concurrent targeting of MAP3K3 and BRD4 by miR-3140-3p overcomes acquired resistance to BET inhibitors in neuroblastoma cells
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Obesity accelerates hair thinning by stem cell-centric converging mechanisms
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m6A-mediated alternative splicing coupled with nonsense-mediated mRNA decay regulates SAM synthetase homeostasis
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Job Opportunity: Faculty Position (Assistant Professor) Department of Medical Chemistry
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DNA damage in embryonic neural stem cell determines FTLDs' fate via early-stage neuronal necrosis
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Immunoglobulin A–specific deficiency induces spontaneous inflammation specifically in the ileum
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Identification of PDHX as a metabolic target for esophageal squamous cell carcinoma
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HERV-Derived Ervpb1 Is Conserved in Simiiformes, Exhibiting Expression in Hematopoietic Cell Lineages Including Macrophages
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Job Opportunity: Faculty Position (Assistant Professor) Department of Structural Biology
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Label‐free quality control and identification of human keratinocyte stem cells by deep learning‐based automated cell tracking
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Job Opportunity: Faculty Position (Assistant Professor) the Laboratory for integrated research projects on intractable diseases: IBD project.
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Job Opportunity: Faculty Position (Assistant Professor) Department of Neuropathology
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A missense variant in NUF2, a component of the kinetochore NDC80 complex, causes impaired chromosome segregation and aneuploidy associated with microcephaly and short stature
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An Antibody-Drug Conjugate That Selectively Targets Human Monocyte Progenitors for Anti-Cancer Therapy
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Distinct types of stem cell divisions determine organ regeneration and aging in hair follicles
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Suppression of MET signaling mediated by pitavastatin and capmatinib inhibits oral and esophageal cancer cell growth
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A Guillain-Barré syndrome-associated SIGLEC10 rare variant impairs its recognition of gangliosides
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Improving the Efficacy of EGFR Inhibitors by Topical Treatment of Cutaneous Squamous Cell Carcinoma with miR-634 Ointment
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WNK regulates Wnt signalling and β-Catenin levels by interfering with the interaction between β-Catenin and GID
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A missense mutation in the RSRSP stretch of Rbm20 causes dilated cardiomyopathy and atrial fibrillation in mice
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Wipi3 is essential for alternative autophagy and its loss causes neurodegeneration
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IRF2 maintains the stemness of colonic stem cells by limiting physiological stress from interferon
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Generation of three-dimensional heart organoids
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RTL1 Gene a Likely Culprit Behind Temple and Kagami-Ogata Syndromes
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Increasing the Effectiveness of Cancer Treatments: Anti-PD-L1 Immunotherapy
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A new molecular guardian of intestinal stem cells
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Potential target identified for migraine therapy
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Characterization of radioresistant epithelial stem cell heterogeneity in the damaged mouse intestine
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How Stress Affects Bone Marrow
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Glioma stem cell (GSC)‐derived autoschizis‐like products confer GSC niche properties involving M1‐like tumor‐associated macrophages
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miR-1293, a candidate for miRNA-based cancer therapeutics, simultaneously targets BRD4 and the DNA repair pathway
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How Cells Decide the Way They Want to Recycle Their Content
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Estradiol/GPER affects the integrity of mammary duct-like structures in vitro
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Timing of Brain Cell Death Uncovers a New Target for Alzheimer’s Treatment
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Development of anticancer drug with tumor-suppressive miR-634 as a drug seed for the nucleic acid therapeutics