研究業績

2010 2009 2008 2007 2006 2005
著書 英文総説 和文総説

2010

  1. Tetsuo Narumi, Chihiro Ochiai, Kazuhisa Yoshimura, Shigeyoshi Harada, Tomohiro Tanaka, Wataru Nomura, Hiroshi Arai, Taro Ozaki, Nami Ohashi, Shuzo Matsushita & Hirokazu Tamamura
    CD4 Mimics Targeting the HIV Entry Mechanism and their Hybrid Molecules with a CXCR4 Antagonist
    Bioorg. Med. Chem. Lett., In press
  2. Shintaro Suzuki, Kasthuraiah Maddali, Chie Hashimoto, Emiko Urano, Nami Ohashi, Tomohiro Tanaka, Taro Ozaki, Hiroshi Arai, Hiroshi Tsutsumi, Tetsuo Narumi, Wataru Nomura, Naoki Yamamoto, Yves Pommier, Jun A. Komano & Hirokazu Tamamura
    Peptidic HIV Integrase Inhibitors Derived from HIV Gene Products: Structure-Activity Relationship Studies.
    Bioorg. Med. Chem., In press
  3. Shintaro Suzuki, Emiko Urano, Chie Hashimoto, Hiroshi Tsutsumi, Toru Nakahara, Tomohiro Tanaka, Yuta Nakanishi, Kasthuraiah Maddali, Yan Han, Makiko Hamatake, Kosuke Miyauchi, Yves Pommier, John A. Beutler, Wataru Sugiura, Hideyoshi Fuji, Tyuji Hoshino, Kyoko Itotani, Wataru Nomura, Tetsuo Narumi, Naoki Yamamoto, Jun A. Komano & Hirokazu Tamamura
    Peptide HIV-1 Integrase Inhibitors from HIV-1 Gene Products.
    J. Med. Chem., 53(14), 5356-5360 (2010)
  4. Kazuhisa Yoshimura, Shigeyoshi Harada, Junji Shibata, Makiko Hatada, Yuko Yamada, Chihiro Ochiai, Hirokazu Tamamura & Shuzo Matsushita
    Enhanced Exposure of Human Immunodeficiency Virus Type 1 Primary Isolate Neutralization Epitopes through Binding of CD4 Mimetic Compounds.
    J. Virol., 84(15), 7558-7568 (2010)
  5. Toru Aoki, Saki Shimizu, Emiko Urano, Yuko Futahashi, Makiko Hamatake, Hirokazu Tamamura, Kazuo Terashima, Tsutomu Murakami, Naoki Yamamoto & Jun Komano
    Improvement of Lentiviral Vector-mediated Gene Transduction by Genetic Engineering of the Structural Protein Pr55Gag.
    Gene Ther., 2010 Apr 22. [Epub ahead of print]
  6. Roberta Melchionna, Anna Di Carlo, Roberta De Mori, Claudia Cappuzzello, Laura Barberi, Antonio Musar?, Chiara Cencioni, Nobutaka Fujii, Hirokazu Tamamura, Marco Crescenzi, Maurizio C. Capogrossi, Monica Napolitano & Antonia Germani
    Induction of Myogenic Differentiation by SDF-1 via CXCR4 and CXCR7 Receptors.
    Muscle Nerve., 41(6), 828-835 (2010)
  7. Wataru Nomura, Tomoaki Mino, Tetsuo Narumi, Nami Ohashi, Akemi Masuda, Chie Hashimoto, Hiroshi Tsutsumi & Hirokazu Tamamura
    Development of Crosslink-Type Tag-Probe Pairs for Fluorescent Imaging of Proteins.
    Biopolymers: Peptide Science, Published Online: May 24 2010, DOI: 10.1002/bip.21444
  8. Toru Nakahara, Wataru Nomura, Kenji Ohba, Aki Ohya, Tomohiro Tanaka, Chie Hashimoto, Tetsuo Narumi, Tsutomu Murakami, Naoki Yamamoto & Hirokazu Tamamura
    Remodeling of Dynamic Structures of HIV-1 Envelope Proteins Leads to Synthetic Antigen Molecules Inducing Neutralizing Antibodies.
    Bioconjugate Chem., 21(4), 709-714 (2010)
  9. Yuko Yamada, Chihiro Ochiai, Kazuhisa Yoshimura, Tomohiro Tanaka, Nami Ohashi, Tetsuo Narumi, Wataru Nomura, Shigeyoshi Harada, Shuzo Matsushita & Hirokazu Tamamura
    CD4 Mimics Targeting the Mechanism of HIV.
    Bioorg. Med. Chem. Lett., 20, 354-358 (2010)

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2009

  1. Hiroshi Tsutsumi, Wataru Nomura, Seiichiro Abe, Tomoaki Mino, Akemi Masuda, Nami Ohashi, Tomohiro Tanaka, Kenji Ohba, Naoki Yamamoto, Kazunari Akiyoshi & Hirokazu Tamamura
    Fluorogenically Active Leucine Zipper Peptides as New Tag-Probe Pairs for Protein Imaging in Living Cells.
    Angew. Chem., Int. Ed., 48, 9164-9166 (2009)
  2. Tomohiro Tanaka, Wataru Nomura, Tetsuo Narumi, Ai Esaka, Shinya Oishi, Nami Ohashi, Kyoko Itotani, Barry J. Evans, Zi-xuan Wang, Stephen C. Peiper, Nobutaka Fujii & Hirokazu Tamamura
    Structure-activity Relationship Study on Artificial CXCR4 Ligands Possessing the Cyclic Pentapeptide Scaffold: The Exploration of Amino Acid Residues of Pentapeptides by Substitutions of Several Aromatic Amino Acids.
    Org. Biomol. Chem., 7, 3805-3809 (2009)
  3. Nami Ohashi, Wataru Nomura, Mai Kato, Tetsuo Narumi, Nancy E. Lewin, Peter M. Blumberg & Hirokazu Tamamura
    Synthesis of Protein Kinase Cδ C1b Domain by Native Chemical Ligation Methodology and Characterization of Its Folding and Ligand Binding.
    J. Pept. Sci., 5(10), 642-646 (2009)
  4. Yuka Inaba, Nobuko Yoshimoto, Yuta Sakamaki, Makoto Nakabayashi, Teikichi Ikura, Hirokazu Tamamura, Nobutoshi Ito, Masato Shimizu & Keiko Yamamoto
    A New Class of Vitamin D Analogues that Induce Structural Rearrangement of the Ligand-Binding Pocket of the Receptor.
    J. Med. Chem., 52(5), 1438-1449 (2009)
  5. Fuminori Mizukoshi, Kenji Baba, Yuko Goto-Koshino, Asuka Setoguchi-Mukai, Yasuhito Fujino, Koichi Ohno, Hirokazu Tamamura, Shinya Oishi, Nobutaka Fujii & Hajime Tsujimoto
    Inhibitory Effect of Newly Developed CXC-Chemokine Receptor 4 Antagonists on the Infection with Feline Immunodeficiency Virus.
    J. Vet. Med. Sci., 71(1), 121-124 (2009)

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2008

  1. Tomohiro Tanaka, Hiroshi Tsutsumi, Wataru Nomura, Yasuaki Tanabe, Nami Ohashi, Ai Esaka, Chihiro Ochiai, Jun Sato, Kyoko Itotani, Tsutomu Murakami, Kenji Ohba, Naoki Yamamoto, Nobutaka Fujii & Hirokazu Tamamura
    Structure-activity Relationship Study of CXCR4 Antagonists Bearing the Cyclic Pentapeptide Scaffold: Identification of the New Pharmacophore.
    Org. Biomol. Chem., 6, 4374-4377 (2008)
  2. Wataru Nomura, Yasuaki Tanabe, Hiroshi Tsutsumi, Tomohiro Tanaka, Kenji Ohba, Naoki Yamamoto & Hirokazu Tamamura
    Fluorophore Labeling Enables Imaging and Evaluation of Specific CXCR4-Ligand Interaction at the Cell Membrane for Fluorescence-Based Screening.
    Bioconjugate Chem., 19, 1917-1920 (2008)
  3. Hirotomo Nakata, Seth M. Steinberg, Yasuhiro Koh, Kenji Maeda, Yoshikazu Takaoka, Hirokazu Tamamura, Nobutaka Fujii & Hiroaki Mitsuya
    Potent Synergistic Anti-Human Immunodeficiency Virus (HIV) Effects Using Combinations of the CCR5 Inhibitor Aplaviroc with Other Anti-HIV Drugs.
    Antimicrob. Agents Chemother., 52(6), 2111-2119 (2008)
  4. Wouter H. P., Driessen, Nobutaka Fujii, Hirokazu Tamamura & Sean M. Sullivan
    Development of Peptide-targeted Lipoplexes to CXCR4-expressing Rat Glioma Cells and Rat Proliferating Endothelial Cells.
    Mol. Ther., 16(3), 516-524 (2008)
  5. Alexander Kasiyanov, Nobutaka Fujii, Hirokazu Tamamura & Huangui Xiong
    Modulation of Network-driven, GABA-mediated Giant Depolarizing Potentials by SDF-1 in Developing Hippocampus.
    Developmental Neuroscience, 30(4), 285-292 (2008)

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2007

  1. Kenji Kabashima, Noriko Shiraishi, Kazunari Sugita, Tomoko Mori, Ayako Onoue, Miwa Kobayashi, Jun-ichi Sakabe, Ryutaro Yoshiki, Hirokazu Tamamura, Nobutaka Fujii, Kayo Inaba & Yoshiki Tokura
    CXCL12-CXCR4 Engagement Is Required for Migration of Cutaneous Dendritic Cells.
    Am. J Pathol., 171(4), 1249-1257 (2007)
  2. Kenji Kabashima, Kazunari Sugita, Noriko Shiraishi, Hirokazu Tamamura, Nobutaka Fujii & Yoshiki Tokura
    CXCR4 Engagement Promotes Dendritic Cell Survival and Maturation.
    Biochem. Biophys. Res. Commun., 361, 1012-1016 (2007)
  3. Hirokazu Tamamura, Tomohiro Tanaka, Hiroshi Tsutsumi, Koji Nemoto, Satoko Mizokami, Nami Ohashi, Shinya Oishi & Nobutaka Fujii
    Versatile Use of Acid-catalyzed Ring-opening of β-Aziridinyl-α,β-enoates to Stereoselective Synthesis of Peptidomimetics.
    Tetrahedron, 63, 9243-9254 (2007)
  4. Yamina A. Berchiche, Ken Y. Chow, Bernard Lagane, Martin Leduc, Yann Percherancier, Nobutaka Fujii, Hirokazu Tamamura, Fran?oise Bachelerie & Nikolaus Heveker
    Direct Assessment of CXCR4 Mutant Conformations Reveals Complex link between Receptor Structure and Galphai Activation.
    J. Biol. Chem. (Commun.), 282, 5111 - 5115 (2007)
  5. Shiro Kubonishi, Tomoko Kikuchi, Shinya Yamaguchi, Hirokazu Tamamura, Nobutaka Fujii, Takeshi Watanabe, Fernando Arenzana-Seisdedos, Kazuma Ikeda, Toshimitsu Matsui, Mitsune Tanimoto & Yoshio Katayama
    Rapid Hematopoietic Progenitor Mobilization by Sulfated Colominic Acid.
    Biochem. Biophys. Res. Commun., 355 (4), 970-975 (2007)
  6. Hiroshi Tsutsumi, Tomohiro Tanaka, Nami Ohashi, Hiroyuki Masuno, Hirokazu Tamamura, Kenichi Hiramatsu, Takanobu Araki, Satoshi Ueda, Shinya Oishi & Nobutaka Fujii
    Therapeutic Potential of the Chemokine Receptor CXCR4 Antagonists as Multi-functional Agents.
    Biopolymers: Peptide Science, 88(2), 279-289 (2007)
  7. Satoshi Ueda, Shinya Oishi, Zi-xuan Wang, Takanobu Araki, Hirokazu Tamamura, Jerome Cluzeau, Hiroaki Ohno, Shuichi Kusano, Hideki Nakashima, John O. Trent, Stephen C. Peiper & Nobutaka Fujii
    Structure-Activity Relationships of Cyclic Peptide-Based Chemokine Receptor CXCR4 Antagonists: Disclosing the Importance of Side-Chain and Backbone Functionalities.
    J. Med. Chem., 50(2), 192-198 (2007)
  8. Hiroshi Tsutsumi, Hirokazu Tamamura & Nobutaka Fujii
    Inhibitors of the Chemokine Receptor CXCR4. Chemotherapy of AIDS, Metastatic Cancer, Leukemia and Rheumatoid Arthritis.
    Lett. Drug Design Discovery, 4, 20-26 (2007)
  9. Hirokazu Tamamura, Hiroshi Tsutsumi, Hiroyuki Masuno & Nobutaka Fujii
    Development of Low Molecular Weight CXCR4 Antagonists by Exploratory Structural Tuning of Cyclic Tetra- and Pentapeptide-scaffolds towards the Treatment of HIV Infection, Cancer Metastasis and Rheumatoid Arthritis.
    Curr. Med. Chem., 14 (1), 93-102 (2007)

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2006

  1. Ayumu Niida, Hiroaki Tanigaki, Eriko Inokuchi, Yoshikazu Sasaki, Shinya Oishi, Hiroaki Ohno, Hirokazu Tamamura, Zixuan Wang, Stephen C. Peiper, Kazuo Kitaura, Akira Otaka & Nobutaka Fujii
    Stereoselective Synthesis of 3,6-Disubstituted-3,6-dihydropyridin-2-ones as Potential Diketopiperazine Mimetics Using Organocopper-Mediated Anti-S(N)2 ' Reactions and Their Use in the Preparation of Low-Molecule CXCR4 Antagonists.
    J. Org. Chem., 71 (10), 3942-3951 (2006)
  2. Hirokazu Tamamura, Hiroshi Tsutsumi, Hiroyuki Masuno, Satoko Mizokami, Kenichi Hiramatsu, Zixuan Wang, John O. Trent, Hideki Nakashima, Naoki Yamamoto, Stephen C. Peiper & Nobutaka Fujii
    Development of a Linear Type of Low Molecular Weight CXCR4 Antagonists Based on T140 Analogs.
    Org. Biomol. Chem., 4, 2354-2357 (2006)
  3. Hirokazu Tamamura, Akio Ojida, Teppei Ogawa, Hiroshi Tsutsumi, Hiroyuki Masuno, Hideki Nakashima, Naoki Yamamoto, Itaru Hamachi & Nobutaka Fujii
    Identification of a New Class of Low Molecular Weight Antagonists against the Chemokine Receptor CXCR4 Having the Dipicolylamine-Zinc(II) Complex Structure.
    J. Med. Chem., 49 (11), 3412-3415 (2006)
  4. Eline Menu, Kewal Asosingh, Stefano Indraccolo, Hendrik De Raeve, Ivan Van Riet, Els Van Valckenborgh, Isabelle Vande Broek, Nobutaka Fujii, Hirokazu Tamamura, Ben Van Camp & Karin Vanderkerken
    The Involvement of Stromal Derived Factor 1α in Homing and Progression of Multiple Myeloma in the 5TMM Model.
    Haematologica/the Hematology Journal, 91(5), 605-612 (2006)
  5. Hirofumi Hanaoka, Takahiro Mukai, Hirokazu Tamamura, Tomohiko Mori, Seigo Ishino, Kazuma Ogawa, Yasuhiko Iida, Ryuichiro Doi, Nobutaka Fujii & Hideo Saji
    Development of a In-111-Labeled Peptide Derivative Targeting a Chemokine Receptor, CXCR4, for Imaging Tumors.
    Nucl. Med. Biol., 33 (4), 489-494 (2006)
  6. Alexander Kasyanov, Hirokazu Tamamura, Nobutaka Fujii & Huangui Xiong
    HIV-1 gp120 Enhances Giant Depolarizing Potentials via Chemokine Receptor CXCR4 in Neonatal Rat Hippocampus.
    Eur. J. Neuroscience, 23, 1120-1128 (2006)
  7. Shinya Oishi, Kazuhide Miyamoto, Ayumu Niida, Mikio Yamamoto, Keiichi Ajito, Hirokazu Tamamura, Akira Otaka, Yoshihiro Kuroda, Akira Asai & Nobutaka Fujii
    Application of Tri- and Tetrasubstituted Alkene Dipeptide Mimetics to Conformational Studies of Cyclic RGD Peptides.
    Tetrahedron, 62, 1416-1424 (2006)
  8. Hirokazu Tamamura & Hiroshi Tsutsumi
    Specific Probes for Chemokine Receptors.
    Chem. Biol., 13, 8-10 (2006)
  9. Ayumu Niida, Zixuan Wang, Kenji Tomita, Shinya Oishi, Hirokazu Tamamura, Akira Otaka, Jean-Marc Navenot, James R. Broach, Stephen C. Peiper & Nobutaka Fujii
    Design and Synthesis of Downsized Metastin (45-54) Analogs with Maintenance of High GPR54 Agonistic Activity.
    Bioorg. Med. Chem. Lett., 16(1), 134-137 (2006)

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2005

  1. Hirokazu Tamamura, Ai Esaka, Teppei Ogawa, Takanobu Araki, Satoshi Ueda, Zixuan Wang, John O. Trent, Hiroshi Tsutsumi, Hiroyuki Masuno, Hideki Nakashima, Naoki Yamamoto, Stephen C. Peiper, Akira Otaka & Nobutaka Fujii
    Structure-activity Relationship Studies on CXCR4 Antagonists Having Cyclic Pentapeptide Scaffolds.
    Org. Biomol. Chem., 3, 4392-4394 (2005)
  2. Margitta Retz, Sachdev S. Sidhu, Jan Lehmann, Hirokazu Tamamura, Nobutaka Fujii & Carol Basbaum
    New HIV-Drug Inhibits in Vitro Bladder Cancer Migration and Invasion.
    Eur. Urol., 48 (6), 1025-1030 (2005)
  3. Satoshi Ueda, Mizuno Fujita, Hirokazu Tamamura, Nobutaka Fujii & Akira Otaka
    Photolabile Protection for One-Pot Sequential Native Chemical Ligation.
    ChemBioChem, 6 (11), 1983-1986 (2005)
  4. Jayendra B. Bhonsle, Zi-xuan Wang, Hirokazu Tamamura, Nobutaka Fujii, Stephen C. Peiper & John O. Trent
    A Simple, Automated Quasi-4D-QSAR, Quasi-multi Way PLS Approach to Develop Highly Predictive QSAR Models for Highly Flexible CXCR4 Inhibitor Cyclic Peptide Ligands Using Scripted Common Molecular Modeling Tools.
    QSAR Comb. Sci., 24 (5), 620-630 (2005)
  5. Ayumu Niida, Shinya Oishi, Yoshikazu Sasaki, Makiko Mizumoto, Hirokazu Tamamura, Nobutaka Fujii & Akira Otaka
    Facile Access to (Z)-Alkene-containing Diketopiperazine Mimetics Utilizing Organocopper-mediated Anti-SN2' Reactions.
    Tetrahedron Lett., 46, 4183-4186 (2005)
  6. Meike Burger, Tanja Hartmann, Myriam Krome, Justyna Rawluk, Hirokazu Tamamura, Nobutaka Fujii, Thomas J. Kipps & Jan A. Burger
    Small Peptide Inhibitors of the CXCR4 Chemokine Receptor (CD184) Antagonize the Activation, Migration and Antiapoptotic Responses of CXCL12 in Chronic Lymphocytic Leukemia B Cells.
    Blood, 106 (5), 1824-1830 (2005)
  7. Hirokazu Tamamura, Takanobu Araki, Satoshi Ueda, Zixuan Wang, Shinya Oishi, Ai Esaka, John O. Trent, Hideki Nakashima, Naoki Yamamoto, Stephen C. Peiper, Akira Otaka & Nobutaka Fujii
    Identification of Novel Low Molecular Weight CXCR4 Antagonists by Structural Tuning of Cyclic Tetrapeptide-scaffolds.
    J. Med. Chem., 48, 3280-3289 (2005)
  8. Yann Percherancier, Yamina Berchiche, Isabelle Slight, Rudolf Volkmer-Engert, Hirokazu Tamamura, Nobutaka Fujii, Michel Bouvier & Nikolaus Heveker
    Bioluminescence Resonance Energy Transfer Reveals Ligand-induced Conformational Changes in CXCR4 Homo- and Heterodimers.
    J. Biol. Chem., 280, 9895 - 9903 (2005)
  9. Andrew C. W. Zannettino, Amanda N. Farrugia, Angela Kortesidis, Jim Manavis, Luen B. To, Sally K. Martin, Peter Diamond, Hirokazu Tamamura, Tsvee Lapidot, Nobutaka Fujii & Stan Gronthos
    Elevated Serum Levels of SDF-1α are Associated with Increased Osteoclast Activity and Osteolytic Bone Disease in Multiple Myeloma Patients.
    Cancer Res., 65(5), 1700-1709 (2005)
  10. Daisuke Nameki, Eiichi Kodama, Mieko Ikeuchi, Naoto Mabuchi, Akira Otaka, Hirokazu Tamamura, Mutsuhito Ohno, Nobutaka Fujii & Masao Matsuoka
    Mutations Conferring Resistance to HIV-1 Fusion Inhibitors Are Restricted by gp41 and Rev Responsive Element Functions.
    J. Virol., 79, 764-770 (2005)
  11. Hirokazu Tamamura, Kenichi Hiramatsu, Satoshi Ueda, Zixuan Wang, Shuichi Kusano, Shigemi Terakubo, John O. Trent, Stephen C. Peiper, Naoki Yamamoto, Hideki Nakashima, Akira Otaka & Nobutaka Fujii
    Stereoselective Synthesis of [L-Arg, L/D-3-(2-naphthyl)alanine]-Type (E)-Alkene Dipeptide Isosteres and its Application to the Synthesis and Biological Evaluation of Pseudopeptide Analogs of the CXCR4 Antagonist FC131.
    J. Med. Chem., 48, 380-391 (2005)
  12. Erich Piovan, Valeria Tosello, Stefano Indraccolo, Anna Cabrelle, Ilenia Baesso, Livio Trentin, Rita Zamarchi, Hirokazu Tamamura, Nobutaka Fujii, Gianpietro Semenzato, Luigi-Chieco Bianchi & Alberto Amadori
    Chemokine Receptor Expression in EBV-associated Lymphoproliferation in Hu/SCID Mice: Implications for CXCL12/CXCR4 Axis in Lymphoma Generation.
    Blood, 105, 931-939 (2005)

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著書

  1. Tanaka T, Nomura W, Narumi T, Yoshimura K, Matsushita S, Murakami T,　Komano J, Yamamoto N & Tamamura H
    From reverse to forward chemical genomics: Development of anti-HIV agent.
    Peptide Science 2009, Kouji Okamoto (Ed.), The Japanese peptide Society, Osaka, 105-106, 2010.
  2. Tamamura H, Tanaka T, Tsutsumi H, Nemoto K, Mizokami S, Ohashi N, Oishi S & Fujii N
    Stereoselective Synthesis of Peptidomimetics Based on Acid-catalyzed Ring-opening of beta-Aziridinyl-alpha,beta-enoates.
    Peptides for Youth, S. Del Valle, E. Escher and W. D. Lubell (Eds.), The American peptide Society, USA, 149-150, 2009.
  3. Tamamura H, Tanaka T, Tsutsumi H, Ohashi N, Hiramatsu K, Araki T, Ojida A, Hamachi I, Wang Z, Peiper SC, Trent JO, Ueda S, Oishi S, Fujii N
    Development of Chemokine Receptor CXCR4 Antagonists Using Bio-mimetic Strategy.
    Peptides for Youth, S. Del Valle, E. Escher and W. D. Lubell (Eds.), The American peptide Society, USA, 145-146, 2009.
  4. Tanaka T, Tsutsumi H, Nomura W, Tanabe Y, Ohashi N, Esaka A, Ochiai C, Sato J, Itotani K, Murakami T,　Ohba K, Yamamoto N, Fujii N & Tamamura H
    Structure-activity relationship study of CXCR4 antagonists on the cyclic pentapeptide scaffold: Identification of new pharmacophore moieties.
    Peptide Science 2008, Motoyoshi Nomizu (Ed.), The Japanese peptide Society, Osaka, 273-276, 2009.
  5. Kobayashi K, Narumi T, Oishi S, Ohno H, Fujii N
    Diastereoselective synthesis of trifuluoromethylalkene dipeptide isosters based on nucleophilic trifluoromethylaion.
    Peptide Science 2008, Motoyoshi Nomizu(Eds.), The Japanese peptide Society, Osaka, 13-14, 2009.
  6. Ohashi N, Kato M, Matsumoto H, Tanaka T, Tsutsumi H, Masuno H, Nomura W, Yoshida K, Ikura T, Ito N & Tamamura H.
    Chemical Synthesis of a PKC C1b Domain by a Peptide Ligation Method and Expression of the Protein in E. coli and Their Application.
    4th International Peptide Symposium, Cairn, Australia, Oct21-25, 2007, in press.
  7. Tamamura H, Komano A, Nakahara T, Ohashi1 N, Tanaka T, Tsutsumi H, Nomura W, Urano E, Hua Y, Fuji H, Hamatake M, Miyauchi K, Morikawa Y, Hoshino T, Sugiura W & Yamamoto N.
    Identification of Sequential Motifs Relevant to Inhibitory Activity against HIV Integrase.
    4th International Peptide Symposium, Cairn, Australia, Oct21-25, 2007, in press.
  8. Tsutsumi H, Tanabe Y, Abe S, Mino T, Ohashi N, Tanaka T, Nomura W & Tamamura H.
    Development of Peptide Tools for Fluorescence Imaging of Proteins in Living Cells.
    Peptide Science 2007, Saburo Amimoto and Shin Ono,(Eds.), The Japanese peptide Society, Osaka, 95-96, 2008.
  9. Tamamura H, Komano A, Nakahara T, Ohashi N, Tanaka T, Tsutsumi H, Nomura W, Urano E, Hua Y, Fuji H, Hamatake M, Miyauchi K, Morikawa Y, Hoshino T, Sugiura W & Yamamoto　N.
    Identification of Sequential Motifs Relevant to Inhibitory Activity against HIV Integrase.
    Peptide Science 2007, Saburo Amimoto and Shin Ono (Eds.), The Japanese peptide Society, Osaka, 335-336, 2008.
  10. Tamamura H, Tsutsumi H Masuno H, Ogawa T, Kenichi Hiramatsu K, Takanobu Araki T, Ueda S, Oishi S, Esaka A, Tanaka T, Ohashi N, Wang Z, Peiper SC, Trent JO, ＆ Fujii N
    Synthesis and biological evaluation of CXCR4 antagonists as pharmaceutical agents,
    Peptides 2006, Rolka K. and. Rekowski P. and. Silberring J.,(Eds.), KENES, Geneva, 110-111, 2007.
  11. 濱崎啓太、堤浩
    ナノマテリアル・シクロデキストリン.
    pp129-148．シクロデキストリン学会編．米田出版．2005．

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英文総説

  1. Hirokazu Tamamura, Hiroshi Tsutsumi, Wataru Nomura, Tomohiro Tanaka & Nobutaka Fujii
    A Future Perspective on the Development of Chemokine Receptor CXCR4 Antagonists.
    Expert Opin. Drug Discovery, 3(10), 1155-1166 (2008)
  2. Hirokazu Tamamura, Hiroshi Tsutsumi, Wataru Nomura & Nobutaka Fujii
    Exploratory Studies on Development of the Chemokine Receptor CXCR4 Antagonists toward Downsizing.
    Perspectives in Medicinal Chemistry, 2, 1-9 (2008)
  3. Hiroshi Tsutsumi, Hirokazu Tamamura & Nobutaka Fujii
    Inhibitors of the Chemokine Receptor CXCR4. Chemotherapy of AIDS, Metastatic Cancer, Leukemia and Rheumatoid Arthritis.
    Lett. Drug Design Discovery, 4, 20-26 (2007)
  4. Hirokazu Tamamura, Hiroshi Tsutsumi, Hiroyuki Masuno & Nobutaka Fujii
    Development of Low Molecular Weight CXCR4 Antagonists by Exploratory Structural Tuning of Cyclic Tetra- and Pentapeptide-scaffolds towards the Treatment of HIV Infection, Cancer Metastasis and Rheumatoid Arthritis.
    Curr. Med. Chem., 14 (1), 93-102 (2007)
  5. Hirokazu Tamamura, Hiroshi Tsutsumi & Nobutaka Fujii
    The Chemokine Receptor CXCR4 as a Therapeutic Target for Several Diseases.
    Mini-Rev. Med. Chem., 6, 989-995 (2006)
  6. Hirokazu Tamamura & Nobutaka Fujii
    The Therapeutic Potential of CXCR4 Antagonists in the Treatment of HIV Infection, Cancer Metastasis and Rheumatoid Arthritis.
    Expert Opin. Ther. Targets, 9 (6),1267-1282 (2005)
  7. Hirokazu Tamamura, Akira Otaka & Nobutaka Fujii
    Development of Anti-HIV Agents Targeting Dynamic Supramolecular Mechanism: Entry and Fusion Inhibitors Based on CXCR4/CCR5 Antagonists and gp41-C34-Remodeling Peptides.
    Curr. HIV Res., 3 (4), 289 - 301 (2005)

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和文総説

  1. 鳴海哲夫、玉村啓和
    「ペプチドミメティックによる創薬研究」
    「生化学」特集号「ペプチド科学と生化学の接点」（日本生化学会　東京）、第82巻6号　頁515−523、2010年
  2. 野村　渉、増田朱美、玉村啓和
    「エピジェネティクな遺伝子発現制御のためのDNAメチル化酵素の創製」
    「生化学」ミニレビュウ（日本生化学会　東京）、第82巻5号　頁393−397、2010年
  3. 玉村啓和
    「種々の作用点をターゲットとした抗HIV剤の創製」
    日本エイズ学会誌　（日本エイズ学会）、11巻、2号、頁100-101、2009年
  4. 玉村啓和
    「PK-Cを標的としたdiacylglycerolの環化誘導体の創製」
    ファルマシア　最前線（日本薬学会）、42巻、5号、頁431-435、2006年
  5. 玉村啓和
    「抗ウイルス薬・抗AIDS (HIV)薬」
    BIO Clinica（北隆館　東京）、21巻、3号、頁224-230、2006年
  6. 藤井信孝、大高章、玉村啓和
    「ケミカルプロテオミクスによる創薬基盤の革新―情報から制御へ」
    細胞工学　特集　飛躍するケミカルバイオロジー: 化学から生命現象を明らかに　(秀潤社　東京）、24巻、11号、頁1181-1186、2005年

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