top > Div. of Biofunctional Molecules > Dept. of Biosensors

  • Div. of Biomedical Materials
  • Div. of Biofunctional Restoration
  • Div. of Medical Devices
  • Div. of Biomolecular Chemistry
  • Medical and Dental Device Technology Incubation Center
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Member

H. Kobayashi Invited Prof

Research Theme

  1. Development of an artificial cornea
    An artificial cornea stabilizing among the living bodies for a long term by immobilizing a physiology activity material on the surface of transparent synthetic hydrogel is under development. And also we try to develop the engineered cornea by tissue engineering approach.
  2. Development of living body information sensing technology with eyes
    We aim at construction of a new living body information monitoring system by using eyes including transparent tissue such as cornea, crystalline lens, and vitreous humor as a place of sensing. For example, diabetes causes a disease of eyes such as a cataract or glaucoma as a complication. It is known that composition of aqueous humor and tears liquid has composition of plasma and some correlation. That simpleness and easiness can measure various condition of a patient such as abnormality of blood sugar value by developing a system monitoring an intraocular pressure and eyes liquid composition is expected.

Publications

  1. Miyashita H, Shimmura S, Kobayashi H, Taguchi T, Asano-Kato N, Uchino Y, Kato M, Shimazaki J, Tanaka J, Tsubota K, Collagen-immobilized poly (vinyl alcohol) as an artificial cornea scaffold that supports a stratified corneal epithelium, J Biomed Mater Res B Appl Biomater 76B(1): 56-63, 2006
  2. Shimmura S, Miyashita H, Uchino Y, Taguchi T, Kobayashi H, Shimazaki J, Tanaka J, Tsubota K, Microkeratome assisted deep lamellar keratoprosthesis, Br J Ophthalmol 907:826-829, 2006
  3. Shimmura S, Miyashita H, Konomi K, Shinozaki N, Taguchi T, Kobayashi H, Shimazaki J, Tanaka J, Tsubota K, Transplantation of corneal endothelium with Descemet's membrane using a hyroxyethyl methacrylate polymer as a carrier, Br J Ophthalmol 892: 134-137, 2006
  4. Tian F, Cui D, Schwarz H, Estrada GG, Kobayashi H, Cytotoxicity of single-wall carbon nanotubes on human fibroblasts, Toxicol In Vitro 207: 1202-12, 2006
  5. Satomi T, Ueno K, Fujita Y, Kobayashi H, Tanaka J, Mitamura Y, Tateishi T, OtsukaH, Synthesis of polypyridine-graft-PEG copolymer for protein repellent and stable interface, J Nanosci & Nanotech 66: 1792-1796, 2006
  6. Taguchi T, Saito H, Aoki H, Uchida Y, Sakane M, Kobayashi H, Tanaka J, Biocompatible high-strength glue consisting of citric acid derivative and collagen, Materials science & Engineering C-Biomimetic and Supramolecular Systems 261: 9-13, 2006
  7. Satomi T, Ueno K, Fujita Y, Tanaka J, Otsuka H, Kobayashi H, Taguchi T, Tateishi T, Mitamura Y, Synthesisi of Polypyridine-Graft-PEG Copolymer for Protein Repellent and Stable Interface, J Nanosci & Nanotech 6: 1792-1796, 2006

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