2022年度 業績

英語原著論文

Autologous Synovial Mesenchymal Stem Cell Transplantation Suppresses Inflammation Caused by Synovial Harvesting and Promotes Healing in a Micro Minipig Repaired Meniscus Model.
Nobutake Ozeki, Mitsuru Mizuno, Shinobu Yanada, Takuya Okada, Rei Kubota, Yoshihisa Kushida, Hideto Furuoka, Kentaro Endo, Hisako Katano, Kentaro Nakamura, Shoji Ohya, Hideyuki Koga, Ichiro Sekiya.
Transplant Proc. 2023 Mar 10;S0041-1345(23)00014-3.

Association between knee cartilage thickness determined by magnetic resonance imaging three-dimensional analysis and the International Cartilage Repair Society (ICRS) arthroscopic grade.
Nobutake Ozeki, Hideyuki Koga, Yusuke Nakagawa, Hiroki Katagiri, Hisako Katano, Makoto Tomita, Jun Masumoto, Ichiro Sekiya.
Knee 2023 Mar 21;42:90-98.

Effect of disinfectants and manual wiping for processing the cell product changeover in a biosafety cabinet.
Mizuno M, Matsuda J, Watanabe K, Shimizu N, Sekiya I.
Regen Ther. 2023 Feb 9;22:169-175.

Cross-contamination risk and decontamination during changeover after cell-product processing.
Mitsuru Mizuno, Kouichirou Yori, Toshikazu Takeuchi, Tetsuya Yamaguchi, Ken Watanabe, Yasuhiro Tomaru, Norio Shimizu, Ichiro Sekiya.
Regen Ther. 2022 Dec 21;22:30-38.

Comparison of adhesion of thawed and cultured synovial mesenchymal stem cells to the porcine meniscus and the relevance of cell surface microspike
Shunichi Fujii, Kentaro Endo, Nobutake Ozeki, Yuriko Sakamaki, Yuji Kohno, Mitsuru Mizuno, Hisako Katano, Kunikazu Tsuji, Hideyuki Koga, Ichiro Sekiya.
BMC Mol Cell Biol. 2022 Dec 12;23(1):53.

Comparison of the yields and properties of dedifferentiated fat cells and mesenchymal stem cells derived from infrapatellar fat pads
Shunichi Fujii, Kentaro Endo, Seiya Matsuda, Ichiro Sekiya.
Regen Ther. 2022 Nov Nov 29;21:611-619.

Stress and motivation of cell processing operators: A pilot study of an online questionnaire survey.
Mizuno M, Sugahara Y, Iwayama D, Miyashita N, Katano H, Sekiya I.
Regen Ther. 2022 Nov 4;21:547-552.

The 16th International Workshop on Osteoarthritis Imaging:“New insightson treatment and imaging: A :couple that belongs together"
Sekiya I, Ozek N.
Osteoarthritis Imaging. Volume 2, Supplement 1.

Human synovial mesenchymal stem cells show time-dependent morphological changes and increased adhesion to degenerated porcine cartilage.
Tanimoto T, Endo K, Sakamaki Y, Ozeki N, Katano H, Mizuno M, Koga H, Sekiya I.
Sci Rep. 2022 Oct 5;12(1):16619.

Medial tibial osteophyte width strongly reflects medial meniscus extrusion distance and medial joint space width moderately reflects cartilage thickness in knee radiographs.
Sekiya I, Sasaki S, Miura Y, Aoki H, Katano H, Okanouchi N, Tomita M, Masumoto J, Koga H, Ozeki N.
JMRI. 2022 Sep;56(3):824-834

Integrin β1, PDGFRβ, and type II collagen are essential for meniscus regeneration by synovial mesenchymal stem cells in rats.
Kitahashi T, Kogawa R, Nakamura K, Sekiya I.
Sci Rep. 2022 Aug 19;12(1):14148.

Second-look arthroscopy after meniscus repair and synovial mesenchymal stem cell transplantation to treat degenerative flaps and radial tears of the medial meniscus: A case report.
Sekiya I, Koga H, Katano H, Mizuno M, Kohno Y, Otabe K, Ozeki N.
J Orthop Sci. 2022 Jul;27(4):821-834.

Clearance of senescent cells with ABT-263 improves biological functions of synovial mesenchymal stem cells from osteoarthritis patients.
Miura Y, Endo K, Komori K, Sekiya I.
Stem Cell Res Ther. 2022 Jun 3;13(1):222.

Cell membrane fluidity and ROS resistance define DMSO tolerance of cryopreserved synovial MSCs and HUVECs.
Mizuno M, Matsuzaki T, Ozeki N, Katano H, Koga H, Takebe T, Yoshikawa H, Sekiya I.
SCRT. 2022 May; 13(1):177

Biomechanical analysis of a centralization procedure for extruded lateral meniscus after meniscectomy in porcine knee joints.
Kohno Y, Koga H, Ozeki N, Matsuda J, Mizuno M, Katano H, Sekiya I.
JOR. 2022 May; 40(5):1097-1103

Degenerative meniscus in knee osteoarthritis: from pathology to treatment.
Ozeki N, Koga H, Sekiya I.
Life. 2022 Apr; 12(4):603

Yields of mesenchymal stromal cells from synovial fluid reflect those from synovium in patients with rheumatoid arthritis.
Kohno Y, Mizuno M, Endo K, Ozeki N, Katano H, Matsumoto M, Kaneko H, Takazawa Y, Koga H, Sekiya I.
Tissue and Cell. 2022 Apr; 75:101727