2001年
[原著]
  1. Hattori H, Okano M, Yoishino T, Akagi T, Nakayama E, Saito C, Satoskar A R, Ogawa T, Azuma M, Nishizaki K. Expression of costimulatoryCD80/CD86-CD28/CD152 molecules in nasal mucosa of patients with perennial allergic rhinitis. Clin Exp Allergy 2001;31:1242-9.

  1. Nuriya S, Enomoto S, Azuma M. The role of CTLA-4 in murinecontacthypersensivity. J Invest Dermatol 2001;116:764-768.

  1. Ebata T, Mogi S, Hata Y,Fujimoto J,Okumura K,Azuma M. Rapid induction of CD95 ligand and CD4+ T cell-mediated apoptosis by CD137 (4-1BB) costimulation. Eur J Immunol 2001;31:1410-1416.

  1. Nozawa K,Ohata J, Sakurai J, Hashimoto H, Yagita H, Okumura K, Azuma M. Preferential blockade of CD8+ T cell responses by administration of anti-CD137 ligand monoclonal antibody results in differential effect on development of murine acute chronic graft-vs-host diseases. J Immunol 2001;167:4981-4986.

  1. Guo Z, Wu T, Kirchhof N, Mital D,　Williams J M, Azuma M, Sutherland D E R, Hering B J. Immunotherapy with nondepleting anti-CD4 monoclonal antibodies but not CD28 antagonists protects islet graft in spontaneously diabetic NOD mice from autoimmune destruction and allogeneic and zenogeneic graft rejection. Transplantation 2001;71:1656-1665.

  1. Okano M, Azuma M, Yoshino T, Hattori H, Nakada M, Satoskar A R, Harn D A, Nakayama E, Akagi T, Nishizaki K. Differential role of CD80 and CD86 molecules in the induction and the effector phases of allergic rhinitis in mice. Am J Respir Crit Care Med 2001;164:1501-1507.


  1. Iwakami S, Setoguchi Y, Saijo Y, Azuma M, Fukuchi Y. Replication-deficient adenovirus-mediated transfer of B7-1 (CD80) cDNA induced anti-tumour immunity in isolated human lung cancer. Respirology 2001;6:135-144.

  1. Seko Y, Takahashi N, Oshima H, Shimozato O, Akiba H, Takeda K, Kobata T, Yagita H, Okumura K, Azuma M, Nagai R. Expression of tumour necrosis factor )TNF) ligand superfamily co-stimulatory molecules CD30L, CD27L, OX40L, and 4-1BBL in murine hearts with acute myocarditis caused by Coxsackievirus B3. J Pathol 2001;195:593-603.

  1. A. Terauchi, K. Hayashi, D. Kitamura, Y. Kozono, N. Motoyama and T. Azuma: Pivotal role for DNase I-sensitive regions 3b and/or 4 in the induction of somatic hypermutation of IgH genes. J. Immunol. , 2001; 167: 811-820

  1. 橋本博史,吉木　敬，鈴木和男，徳永勝士，有村義宏，吉田雅治，沼野藤夫，安田　慶秀，中林公正，小林茂人，居石克夫，津坂憲政，中島伸之，重松 宏，小林 靖，由谷親夫，能勢眞人,尾崎承一，金井芳之，濱野慶朋，鈴木　登，松岡康夫，吉田俊治，川崎富夫，森下竜一，東みゆき，西村泰治，稲葉　裕，福原俊一．厚生労働省厚生科学特定疾患・難治性血管炎に関する調査研究報告. 日本臨床免疫学会会誌2001;24:336-346.

[総説]
  1. 大畑順子，東みゆき.co-stimulation. 分子細胞治療 2001;2:202-204
  2. 岡野光博，東みゆき　CD80/CD86^CD28/CTLA4分子とIgE産生．喘息 2001;14:93-97
  3. 東みゆき. 破骨細胞分化と免疫細胞.口病誌 2001;68:221　
  4. 岩井秀之，東みゆき. 第３のT細胞共刺激分子としてのICOS/AILIM. 臨床免疫 2001;36:344-350
  5. 津島文彦，岩井秀之，東みゆき.ICOS (inducible costimulator)とTh2. アレルギー科 2001;12:291-297
  6. 大畑順子，東みゆき.免疫応答と共刺激(Costimulation)．血液フロンテイア 2001;11:21-30.
  7. 小園裕子，抗体の高親和性獲得と補受容体の役割．臨床免疫. 2001; 36:60-66.