No	Primary site	Gender	Age	Sample pathology	TN staging	Smoking	Remarks
1	Buccal mucosa	F	75	M/D SCC YK-4C	T2N0	Current
2	Upper gingiva	F	76	W/D SCC YK-3	T1N0	Never	Pre ope. CRT
3	Upper gingiva	M	69	M/D SCC YK-4C	T4aN0	Never
4	Tongue	M	67	M/D SCC YK-4C	T3N1	Former
5	Buccal mucosa	M	73	W/D SCC YK-3	T2N0	Current
6	Tongue	F	71	Papillary SCC	T1N0	Never
7	Tongue	M	59	M/D SCC YK-4C	T2N0	Former
8	Floor of mouth	M	65	W/D SCC YK-3	T2N0	Current
9	Tongue	M	64	Verrucous Ca	T1N0	Former
10	Tongue	M	59	M/D SCC YK-3	T2N0	Former
11	Buccal mucosa	F	72	P/D SCC YK-4C	T2N0	Former
12	Upper gingiva	F	79	M/D SCC YK-4D	T2N0	Never
13	Tongue	M	72	W/D SCC YK-4C	T1N0	Former
14	Lower gingiva	M	68	W/D SCC YK-2	T1N0	Current
15	Tongue	M	68	W/D SCC YK-2	T2N0	Never	Pre ope. CT
16	Tongue	M	31	W/D SCC YK-2	T2N0	Never
17	Tongue	M	63	M/D SCC YK-4C	T2N0	Current
18	Tongue	F	82	W/D SCC YK-2	T1N0	Never
19	Tongue	M	69	W/D SCC YK-3	T2N2b	Former
20	Buccal mucosa	M	56	W/D SCC YK-3	T1N0	Former	Pre ope. S-1
21	Upper gingiva	F	90	W/D SCC YK-3	T4aN0	Never
22	Upper gingiva	M	81	P/D SCC YK-4C	T2N2c	Former
23	Lower gingiva	F	85	M/D SCC YK-3	T2N0	Never
24	Buccal mucosa	M	81	M/D SCC YK-3	T2N0	Current
25	Floor of mouth	M	67	W/D SCC YK-3	T1N0	ND
26	Floor of mouth	M	80	M/D SCC YK-3	T2N0	ND
27	Buccal mucosa	F	73	M/D SCC YK-4C	T2N1	Never	Pre ope. S-1
28	Upper gingiva	F	76	W/D SCC YK-3	T2N0	Never
29	Tongue	M	78	M/D SCC YK-4C	T3N2bM1	Former	Pre ope. S-1
30	Lower gingiva	F	71	M/D SCC YK-4C	T2N1	Never
31	Tongue	M	42	W/D SCC YK-4C	T2N2b	Never	Pre ope. S-1
32	Buccal mucosa	F	89	M/D SCC YK-3	T4aN0	Never	Pre ope. S-1
33	Tongue	M	65	M/D SCC YK-4C	T3N2c	ND	Pre ope. CT
34	Lower gingiva	M	70	W/D SCC YK-3	T3N2b	Current
35	Tongue	M	75	P/D SCC YK-4C	T2N2c	Never	Pre ope. S-1
36	Upper gingiva	M	74	W/D SCC YK-4C	T2N0	Former
37	Lower gingiva	F	52	M/D SCC YK-4C	T4aN1	Current
38	Lower gingiva	M	73	M/D SCC YK-4C	T4aN2b	Never	Pre ope. S-1
39	Tongue	M	74	M/D SCC YK-3	T2N2b	Current
40	Buccal mucosa	M	79	W/D SCC YK-3	T1N0	Former
41	Lower gingiva	M	61	M/D SCC YK-3	T4aN0	Former
42	Buccal mucosa	F	70	W/D SCC YK-4C	T2N0	Never
43	Lower gingiva	F	68	W/D SCC YK-4C	T2N0	Never
44	Tongue	F	54	M/D SCC YK-4C	T1N1	Never
45	Lower gingiva	F	89	P/D SCC YK-4C	T3N0	Never
46	Tongue	M	74	M/D SCC YK-4C	T4aN2b	Current
47	Buccal mucosa	M	67	W/D SCC YK-3	T2N2b	Former	Pre ope. S-1
48	Tongue	M	43	M/D SCC YK-4C	T2N0	Former
49	Lower gingiva	M	52	W/D SCC YK-3	T4aN0	Never
50	Tongue	F	76	M/D SCC Y-K2	T1N0	Never
51	Tongue	F	59	W/D SCC YK-3	T2N2b	Never
52	Lower gingiva	F	86	W/D SCC YK-3	T1N0	Never
53	Tongue	F	43	W/D SCC YK-3	T1N0	Never
54	Tongue	M	71	M/D SCC YK-3	T1N0	Never
55	Tongue	M	45	W/D SCC YK-3	T1N0	Current
56	Upper gingiva	F	76	P/D SCC YK-4C	T4aN2b	Never	Pre ope. CRT
57	Tongue	F	81	P/D SCC YK-4C	T2N2c	Never	Pre ope. S-1
58	Lower gingiva	M	79	M/D SCC YK-3	T2N0	Current
59	Tongue	F	64	M/D SCC YK-4C	T2N1	Never
60	Tongue	F	75	M/D SCC YK-3	T3N0	Never	Pre ope. S-1
61	Lower gingiva	M	72	M/D SCC YK-3	T4aN2c	Never
62	Upper gingiva	M	66	M/D SCC YK-4C	T4aN0	Never
63	Tongue	F	35	P/D SCC YK-4D	T1N0	Never
64	Lower gingiva	F	68	W/D SCC YK-3	T3N0	Never
65	Lower gingiva	F	80	W/D SCC YK-3	T2N0	Never	Pre ope. S-1
66	Lower gingiva	M	68	M/D SCC YK-3	T4bN0	Never
67	Lower gingiva	M	47	M/D SCC YK-3	T3N0	Never
68	Tongue	M	45	W/D SCC YK-3	T2N0	Never	Pre ope. S-1
69	Floor of mouth	M	71	W/D SCC YK-3	T2N0	Current
70	Buccal mucosa	F	64	M/D SCC YK-4D	T4bN1	ND	Pre ope. S-1
71	Buccal mucosa	M	78	M/D SCC YK-3	T4aN0	ND
72	Tongue	F	80	M/D SCC YK-3	T1N0	ND
73	Lower gingiva	F	85	M/D SCC YK-3	T1N0	ND
74	Lower gingiva	M	67	M/D SCC YK-3	T4bN2b	ND
75	Lower gingiva	F	69	W/D SCC YK-3	T2N0	Never
76	Tongue	M	39	W/D SCC YK-4C	T2N2b	ND
77	Lower gingiva	M	67	M/D SCC YK-4C	T4aN2b	ND
78	Tongue	M	58	M/D SCC YK-3	T2N0	ND
79	Tongue	M	51	M/D SCC YK-4C	T2N0	ND
80	Tongue	M	65	M/D SCC YK-4C	T3N0	ND
81	Upper gingiva	F	79	M/D SCC YK-3	T2N1	ND
82	Tongue	F	76	W/D SCC YK-3	T2N0	ND
83	Tongue	M	74	W/D SCC YK-3	T3N2b	ND
84	Buccal mucosa	F	57	M/D SCC YK-4C	T2N0	ND
85	Lower gingiva	M	77	W/D SCC YK-4C	T2N1	ND
86	Upper gingiva	F	67	M/D SCC YK-3	T2N0	Current
87	Tongue	M	61	P/D SCC YK-4C	T2N2b	Never
88	Buccal mucosa	M	59	W/D SCC YK-3	T2N2b	Never
89	Tongue	M	67	M/D SCC YK-4C	T4aN0	Never
90	Floor of mouth	M	56	M/D SCC YK-3	T4aN2b	Current
91	Tongue	M	66	W/D SCC YK-2	T1N0	Never
92	Lower gingiva	F	71	W/D SCC YK-4C	T2N1	Never
93	Tongue	M	68	M/D SCC YK-4C	T2N1	Current
94	Lower gingiva	M	77	P/D SCC YK-4C	T2N0	Never
95	Tongue	M	32	W/D SCC YK-3	T2N0	Never
96	Tongue	M	59	W/D SCC YK-3	T1N1	Never
97	Lower gingiva	M	66	M/D SCC YK-4C	T2N0	Current
98	Tongue	M	74	P/D SCC YK-4C	T2N2c	Never
99	Tongue	M	67	M/D SCC YK-3	T4aN2c	Never	Pre ope. CT

• W/D, well differentiated; M/D, moderately differentiated; P/D, poorly differentiated; SCC, squamous cell carcinoma.
• YK-, Yamamoto-Kohama classification for the mode of invasion.
  • YK-1, Well-defined borderline.
  • YK-2, Cords, less-marked borderline.
  • YK-3, Groups of cells, no distinct borderline.
  • YK- 4C, Diffuse invasion, cord-like type invasion.
  • YK- 4D, Diffuse invasion, diffuse-type invasion.
• Pre ope. S-1, Patients were administered oral S-1 during the waiting period before surgery.
• Pre ope. CT, Patients were received pre operative chemo-therapy.
• Pre ope. CRT, Patients were received pre operative chemo- and radio-therapy.