分子疫学研究室
Publications
I. Original Articles 2018 1. Hayashi M, Watanabe A, Muramatsu M, Yamashita N. Effectiveness of personal genomic testing for disease-prevention behavior when combined with careful consultation with a physician: a preliminary study. BMC Res Notes. 11:223. (2018) 2. Tanisawa K, Hirose N, Arai Y, Shimokata H, Yamada Y, Kawai H, Kojima M, Obuchi S, Hirano H, Suzuki H, Fujiwara Y, Taniguchi Y, Shinkai S, Ihara K, Sugaya M, Higuchi M, Arai T, Mori S, Sawabe M, Sato N, Muramatsu M, Tanaka M. Inverse association between height-increasing alleles and extreme longevity in Japanese women. J Gerontol A Biol Sci Med Sci. 73:588-595 (2018) 3. Matsuda Y, Tanaka M, Sawabe M, Mori S, Muramatsu M, Mieno MN, Furukawa T, Arai T. Relationship between pancreatic intraepithelial neoplasias, pancreatic ductal adenocarcinomas, and single nucleotide polymorphisms in autopsied elderly patients. Genes Chromosomes Cancer. 57:12-18 (2018) 4. Udagawa S, Katagiri S, Maekawa S, Takeuchi Y, Komazaki R, Ohtsu A, Sasaki N, Shiba T, Watanabe K, Ishihara K, Sato N, Miyasaka N, Izumi Y. Effect of Porphyromonas gingivalis infection in the placenta and umbilical cord in pregnant mice with low birth weight. Acta Odontol Scand. 15:1-9 (2018) 2017 1. Sato N, Sudo K, Mori M, Imai C, Muramatsu M, Sugimoto M. Early gestational maternal low-protein diet diminishes hepatic response to fasting in young adult male mice. Sci Rep. 7:9812 (2017) 2. Dechamethakun S, Muramatsu M. Long noncoding RNA variations in cardiometabolic diseases. J Hum Genet. 62:97-104 (2017) 3. Dechamethakun S, Sato N, Ikeda S, Sawabe M, Mori S, Yamada Y, Tanaka M, Muramatsu M and Arai T. Association of Macrophage Capping Protein (CAPG) Arg335His Polymorphism and Cancer Susceptibility in the Elderly Japanese. Journal of Gerontology and Geriatric Research. 6; 417 (2017) 4. Nishi K, Luo H, Nakabayashi K, Doi K, Ishikura S, Iwaihara Y, Yoshida Y, Tanisawa K, Arai T, Mori S, Sawabe M, Muramatsu M, Tanaka M, Sakata T, Shirasawa S, Tsunoda T. Alpha-kinase 2 Gene Variant Disrupts Filamentous Actin Localization in the Surface Cells of Colorectal Cancer Spheroids. Anticancer Res. 37:3855-3862. (2017) 5. Yamada Y, Sakuma J, Takeuchi I, Yasukochi Y, Kato K, Oguri M, Fujimaki T, Horibe H, Muramatsu M, Sawabe M, Fujiwara Y, Taniguchi Y, Obuchi S, Kawai H, Shinkai S, Mori S, Arai T, Tanaka M. Identification of five genetic variants as novel determinants of type 2 diabetes mellitus in Japanese by exome-wide association studies. Oncotarget. 8:80492-80505. (2017) 6. Yamada Y, Sakuma J, Takeuchi I, Yasukochi Y, Kato K, Oguri M, Fujimaki T, Horibe H, Muramatsu M, Sawabe M, Fujiwara Y, Taniguchi Y, Obuchi S, Kawai H, Shinkai S, Mori S, Arai T, Tanaka M. Identification of polymorphisms in 12q24.1, ACAD10, and BRAP as novel genetic determinants of blood pressure in Japanese by exome-wide association studies. Oncotarget 8:43068-43079. (2017) 7. Yamada Y, Sakuma J, Takeuchi I, Yasukochi Y, Kato K, Oguri M, Fujimaki T, Horibe H, Muramatsu M, Sawabe M, Fujiwara Y, Taniguchi Y, Obuchi S, Kawai H, Shinkai S, Mori S, Arai T, Tanaka M. Identification of eight genetic variants as novel determinants of dyslipidemia in Japanese by exome-wide association studies. Oncotarget. 8:38950-38961 (2017) 8. Yamada Y, Sakuma J, Takeuchi I, Yasukochi Y, Kato K, Oguri M, Fujimaki T, Horibe H, Muramatsu M, Sawabe M, Fujiwara Y, Taniguchi Y, Obuchi S, Kawai H, Shinkai S, Mori S, Arai T, Tanaka M. Identification of rs7350481 at chromosome 11q23.3 as a novel susceptibility locus for metabolic syndrome in Japanese individuals by an exome-wide association study. Oncotarget. 8:39296-39308. (2017) 9. Yamada Y, Sakuma J, Takeuchi I, Yasukochi Y, Kato K, Oguri M, Fujimaki T, Horibe H, Muramatsu M, Sawabe M, Fujiwara Y, Taniguchi Y, Obuchi S, Kawai H, Shinkai S, Mori S, Arai T, Tanaka M. Identification of C21orf59 and ATG2A as novel determinants of renal function-related traits in Japanese by exome-wide association studies. Oncotarget. 8:45259-45273. (2017) 10. Yamada Y, Sakuma J, Takeuchi I, Yasukochi Y, Kato K, Oguri M, Fujimaki T, Horibe H, Muramatsu M, Sawabe M, Fujiwara Y, Taniguchi Y, Obuchi S, Kawai H, Shinkai S, Mori S, Arai T, Tanaka M. Identification of STXBP2 as a novel susceptibility locus for myocardial infarction in Japanese individuals by an exome-wide association study. Oncotarget. 8:33527-33535. (2017) 11. Yamada Y, Sakuma J, Takeuchi I, Yasukochi Y, Kato K, Oguri M, Fujimaki T, Horibe H, Muramatsu M, Sawabe M, Fujiwara Y, Taniguchi Y, Obuchi S, Kawai H, Shinkai S, Mori S, Arai T, Tanaka M. Identification of EGFLAM, SPATC1L and RNASE13 as novel susceptibility loci for aortic aneurysm in Japanese individuals by exome-wide association studies. Int J Mol Med. 39:1091-1100. (2017) 12. Yamada Y, Sakuma J, Takeuchi I, Yasukochi Y, Kato K, Oguri M, Fujimaki T, Horibe H, Muramatsu M, Sawabe M, Fujiwara Y, Taniguchi Y, Obuchi S, Kawai H, Shinkai S, Mori S, Arai T, Tanaka M. Identification of six polymorphisms as novel susceptibility loci for ischemic or hemorrhagic stroke by exome-wide association studies. Int J Mol Med. 39:1477-1491. (2017) 13. Yamada Y, Sakuma J, Takeuchi I, Yasukochi Y, Kato K, Oguri M, Fujimaki T, Horibe H, Muramatsu M, Sawabe M, Fujiwara Y, Taniguchi Y, Obuchi S, Kawai H, Shinkai S, Mori S, Arai T, Tanaka M. Identification of TNFSF13, SPATC1L, SLC22A25 and SALL4 as novel susceptibility loci for atrial fibrillation by an exome‑wide association study. Mol Med Rep. 16:5823-5832 (2017) 14. Komazaki R, Katagiri S, Takahashi H, Maekawa S, Shiba T, Takeuchi Y, Kitajima Y, Ohtsu A, Udagawa S, Sasaki N, Watanabe K, Sato N, Miyasaka N, Eguchi Y, Anzai K, Izumi Y. Periodontal pathogenic bacteria, Aggregatibacter actinomycetemcomitans affect non-alcoholic fatty liver disease by altering gut microbiota and glucose metabolism. Sci Rep. 2017 7:13950 15. Zaw KTT, Sato N, Ikeda S, Thu KS, Mieno MN, Arai T, Mori S, Furukawa T, Sasano T, Sawabe M, Tanaka M, Muramatsu M. Association of ZFHX3 gene variation with atrial fibrillation, cerebral infarction, and lung thromboembolism: An autopsy study. J Cardiol. 70(2):180-184. 2017 2016 1. Thu KS, Sato N, Ikeda S, Naka-Mieno M, Arai T, Mori S, Sawabe M, Muramatsu M, Tanaka M. Association of polymorphisms of the transporter associated with antigen processing (TAP2) gene with pulmonary tuberculosis in an elderly Japanese population. APMIS. 124:675-80. (2016) 2. Zhou H, Mori S, Ishizaki T, Tanaka M, Tanisawa K, Mieno MN, Sawabe M, Arai T, Muramatsu M, Yamada Y, Ito H. Genetic risk score based on the lifetime prevalence of femoral fracture in 924 consecutive autopsies of Japanese males. J Bone Miner Metab. 34:685-691 (2016) 3. Tanisawa K, Arai Y, Hirose N, Shimokata H, Yamada Y, Kawai H, Kojima M, Obuchi S, Hirano H, Yoshida H, Suzuki H, Fujiwara Y, Ihara K, Sugaya M, Arai T, Mori S, Sawabe M, Sato N, Muramatsu M, Higuchi M, Liu YW, Kong QP, Tanaka M. Exome-wide Association Study Identifies CLEC3B Missense Variant p.S106G as Being Associated With Extreme Longevity in East Asian Populations. J Gerontol A Biol Sci Med Sci. [Epub ahead of print] (2016) 2015 1. Yamada M, Sato N, Ikeda S, Arai T, Sawabe M, Mori S, Yamada Y, Muramatsu M, Tanaka M. Association of the chromodomain helicase DNA-binding protein 4 (CHD4) missense variation p.D140E with cancer: potential interaction with smoking. Genes Chromosomes Cancer 54:122-128 (2015) 2. Nishizawa D, Kasai S, Hasegawa J, Sato N, Yamada H, Tanioka F, Nagashima M, Katoh R, Satoh Y, Tagami M, Ujike H, Ozaki N, Inada T, Iwata N, Sora I, Iyo M, Yamada M, Kondo N, Won MJ, Naruse N, Uehara-Aoyama K, Itokawa M, Ohi K, Hashimoto R, Tanisawa K, Arai T, Mori S, Sawabe M, Naka-Mieno M, Yamada Y, Yamada M, Sato N, Muramatsu M, Tanaka M, Irukayama-Tomobe Y, Saito YC, Sakurai T, Hayashida M, Sugimura H, Ikeda K. Associations between the orexin (hypocretin) receptor 2 gene polymorphism Val308Ile and nicotine dependence in genome-wide and subsequent association studies. Mol Brain 8:50 (2015) 3. Zhou H, Mori S, Tanaka M, Sawabe M, Arai T, Muramatsu M, Mieno MN, Shinkai S, Yamada Y, Miyachi M, Murakami H, Sanada K, Ito H. A missense single nucleotide polymorphism, V114I of the Werner syndrome gene, is associated with risk of osteoporosis and femoral fracture in the Japanese population. J Bone Miner Metab. 33:694-700 (2015) 4. Zhou H, Mori S, Ishizaki T, Tanaka M, Tanisawa K, Mieno MN, Sawabe M, Arai T, Muramatsu M, Yamada Y, Ito H. Genetic risk score based on the lifetime prevalence of femoral fracture in 924 consecutive autopsies of Japanese males. J Bone Miner Metab. [Epub ahead of print] (2015) 5. Maekawa K, Nakamura R, Kaniwa N, Mizusawa S, Kitamoto A, Kitamoto T, Ukaji M, Matsuzawa Y, Sugiyama E, Uchida Y, Kurose K, Ueta M, Sotozono C, Ikeda H, Yagami A, Matsukura S, Kinoshita S, Muramatsu M, Ikezawa Z, Sekine A, Furuya H, Takahashi Y, Matsunaga K, Aihara M, Saito Y; Japan Pharmacogenomics Data Science Consortium. Development of a simple genotyping method for the HLA-A*31:01-tagging SNP in Japanese. Pharmacogenomics. 16:1689-99 (2015) 2014 1. Dechamethakun S, Ikeda S, Arai T, Sato T, Sawabe M and Muramatsu M. Associations between the CDKN2A/B, ADTRP and PDGFD Polymorphisms and the Development of Coronary Atherosclerosis in Japanese Patients. J Atheroscler Thromb. 21:680-90 2014 2. Zhao C, Ikeda S, Arai T, Naka-Mieno M, Sato N, Muramatsu M, Sawabe M. Association of the RYR3 gene polymorphisms with atherosclerosis in elderly Japanese population. BMC Cardiovasc Disord. 14:6 2014 3. Parlayan C, Ikeda S, Sato N, Sawabe M, Muramatsu M, Arai T. Association analysis of single nucleotide polymorphisms in miR-146a and miR-196a2 on the prevalence of cancer in elderly Japanese: a case-control study. Asian Pac J Cancer Prev. 15:2101-7 2014 4. Sato N, Htun NC, Daimon M, Tamiya G, Kato T, Kubota I, Ueno Y, Yamashita H, Fukao A, Kayama T, Muramatsu M. Likelihood ratio-based integrated personal risk assessment of type 2 diabetes. Endocr J. 61:967-88. 2014 5. Htun NC, Miyaki K, Zhao C, Muramatsu M, Sato N. Epistasis effects of COMT and MTHFR on inter-individual differences in mental health: under the inverted U-shaped prefrontal dopamine model. Biochem Biophys Res Commun. 451:574-9. 2014 6. Ueta M, Kaniwa N, Sotozono C, Tokunaga K, Saito Y, Sawai H, Miyadera H, Sugiyama E, Maekawa K, Nakamura R, Nagato M, Aihara M, Matsunaga K, Takahashi Y, Furuya H, Muramatsu M, Ikezawa Z, Kinoshita S. Independent strong association of HLA-A*02:06 and HLA-B*44:03 with cold medicine-related Stevens-Johnson syndrome with severe mucosal involvement. Sci Rep. 4:4862. 2014 7. Honma N, Arai T, Muramatsu M. Association between colorectal cancer and estrogens. Nihon Rinsho. 72:49-55 2014 （Japanese） II. Reviews 2012 1. 佐藤憲子　 「DNA 複製、組換えと修復《デブリン生化学第7 版、第4 章、（上代淑人、渋谷正史、井原康夫監訳）丸善出版、2012. 2011 1. 村松正明　 「遺伝子予防医療に対する期待《　ウェルエイジングのための女性医療　太田博明編pp 269-274 メディカルレビュー社、2011. 2005 1. 村松正明　 遺伝子特許　予防医学事典（松島綱治、酒井敏行、石川　昌、稲寺秀邦編集）　289-290　朝倉書店　2005. 2004 1. 村松正明　 ゲノムと疾患 The Frontiers in Medical Sciences 37-43 南山堂　2004. 2. 馬場昌法、村松正明　 ＳＮＰインフォマティクス　ゲノム研究実験ハンドブック　（辻本豪三、田中利男編）153-160　羊土社　2004. 3. 村松正明　 ファーマコゲノミクスの解析技術と応用　1069-1075　月刊薬事　じほう　2004. 4. 村松正明　 遺伝子の個性を生かした医療に向けて　609-614　科学　岩波書店　2004. 5. 村松正明　 癌関連ＳＮＰの探索　戦略と課題　実験医学別冊ポストゲノム研究から診断・治療へ　1927-1931　羊土社　2004. 6. 小田夏奈江、北野宏明、村松正明　 転写因子と糖尿病　1553-1564　臨床検査　2004. 2003 1. 木村友美　村松正明　 ＳＮＰｓとゲノム創薬　ゲノム創薬の展望［Ⅲ］;119　化学フロンティア(12)　化学同人　2003. 2. 木村友美　村松正明　 消化器癌サーベイランスとＳＮＰ　消化器癌サーベイランス；302　新興医学出版社；木村　健・藤盛孝博・加藤　洋/編　2003年10月 3. 村松正明　 SNPs研究の現状と展望　　特集SNPsと消化器疾患　G.I.Research 11;365-371 先端医学社　2003年11月． 2002 1. 村松正明　 遺伝子の個性を医療に生かす　日経サイエンス別冊　54-61　2002年11月． 2. 木村友美　村松正明　 ＤＮＡチップによるＳＮＰ解析　癌と化学療法　29(13):2573-2577　2002． ～2001 1. 村松正明　 ゲノム情報系バイオベンチャー　ゲノム医学の最先端と世界のバイオベンチャー　96-102 羊土社　2001． 2. 村松正明 遺伝子検査の市場と展望：ポストゲノム時代を迎えて 遺伝子医学 55-59, メディカルドウ社 2001. 3. 村松正明編　 SNP の医療創薬への応用とビジネス展開　Bioベンチャー 羊土社 2001. 4. 村松正明　 日本のベンチャーを取り巻く世界　ゲノム医科学がわかる　93-98, 羊土社 2001. 5. 村松正明　 遺伝子の個人差を医療に生かす　日経サイエンス 28-35 2001年12月号． 6. 村松正明　 ゲノム医学入門　高尿酸値血症と痛風 9:164-168 メディカルレビュ-社 2000． 7. 村松正明 DNA チップによるSNP 解析　SNP 遺伝子多型の戦略　128-135,中山書店　2000．