東京医科歯科大学 グローバルCOEプログラム 歯と骨の分子疾患科学 国際教育研究拠点〜デント・メドミクスのインテリジェンスパブ

英文原著論文

Fumitoshi Ishino, Ph.D. 石野史敏

1.

Kagami, M.*, Sekita, Y.*, Nishimura, G., Irie, M., Kato, F., Okada, M., Yamamori, S., Kishimoto, H., Nakayama, M., Tanaka, Y., Matsuoka, K., Takahashi, T., Noguchi, M., Tanaka, Y., Masumoto, K., Utsunomiya, T., Kouzan, H., Komatsu, Y., Ohashi, H., Kurosawa, K., Kosak, K., Ferguson-Smith, A. C., Ishino F. and Ogata, T. Deletions and epimutations affecting the human chromosome 14q32.2 imprinted region in individuals with paternal and maternal upd(14)-like phenotypes. Nat. Genet. 40 (2), 237-242( 2008).

2.

Sekita, Y., Wagatsuma, H., Nakamura, K., Ono, R., Kagami, M., Wakisaka-Saito, N., Hino, T., SuzukiAnnual Report 2008 323 Migishima, R., Kohda, T., Ogura, A., Ogata, T. Yokoyama, M., Kaneko-Ishino T. and Ishino, F. Role of retrotransposon-derived imprinted gene, Rtl1, in the feto-maternal interface of mouse placenta. Nat. Genet. 40(2), 243-248( 2008).

3.

Hikichi, T., Kohda, T., Wakayama, S., Ishino, F. and Wakayama, T. Nuclear transfer alters the DNA methylation status of specific genes in fertilized and parthenogenetically activated mouse embryonic stem cells. Stem Cells. 26(3),783-788( 2008).

4.

Yamamoto, Y., Ishino, F., Kaneko-Ishino, T., Shiura H., Uchio-Yamada, K., Matsuda, J., Suzuki, O. and Sato, K. Type 2 diabetes mellitus in a non-obese mouse model induced by Meg1/Grb10 overexpression. Exp. Animals 57(4), 385-395( 2008). July

5.

Wakisaka, N., Ogonuki, N., Miki, Y., Sekita, Y., Hanaki, K., Aikatsuka, A., Kaneko-Ishino, T., Ishino F., and Ogura, A. Ultrastructure of placental hyperplasia in mice: Comparison of placental phenotypes with three different etiologies. Placenta 29(8), 753-759( 2008).

6.

◎Shiura, H., Nakamura, K., Hikichi, T,. Hino, T., Oda, K., Suzuki-Migishima, R., Kohda, T., Kaneko-Ishino, T., Ishino, F. Paternal deletion of Meg1/Grb10 DMR causes maternalization of the Meg1/Grb10 cluster in mouse proximal Chromosome 11 leading to severe preand postnatal growth retardation. Hum. Mol. Genet.( in press).