東京医科歯科大学 グローバルCOEプログラム 歯と骨の分子疾患科学 国際教育研究拠点〜デント・メドミクスのインテリジェンスパブ

Publication

Yoshio Miki, M.D., Ph.D. 三木義男

1.

Takenaka, K. and Miki, Y. Introduction and characterization of a polymerase-dead point mutation into the POLK gene in vertebrates. FEBS Letters 583: 661-664. 2009

2.

Han, X., Saito, H., Miki, Y.,* and Nakanishi, A. A CRM1- mediated nuclear export signal governs cytoplasmic localization of BRCA2 and is essential for centrosomal localization of BRCA2. Oncogene, 27: 2969-77, 2008. *Corresponding author

3.

Hirai, Y., Banno, K., Suzuki, M., Ichikawa, Y., Udagawa, Y., Sugano, K., and Miki, Y. Molecular epidemiological and mutational analysis of DNA mismatch repair( MMR) genes in endometrial cancer patients with HNPCCassociated familial predisposition to cancer. Cancer Sci, 99: 1715-9, 2008.

4.

Isomura, M., Oya, N., Tachiiri, S., Kaneyasu, Y., Nishimura, Y., Akimoto, T., Hareyama, M., Sugita, T., Mitsuhashi, N., Yamashita, T., Aoki, M., Sai, H., Hirokawa, Y., Sakata, K., Karasawa, K., Tomida, A., Tsuruo, T., Miki, Y.,* Noda, T., and Hiraoka, M. IL12RB2 and ABCA1 genes are associated with susceptibility to radiation dermatitis. Clin Cancer Res, 14: 6683-9, 2008. *Corresponding author

5.

Izawa, N., Matsumoto, S., Manabe, J., Tanizawa, T., Hoshi, M., Shigemitsu, T., Machinami, R., Kanda, H., Takeuchi, K., Miki, Y., Arai, M., Shirahama, S., and Kawaguchi, N. A Japanese patient with Li-Fraumeni syndrome who had nine primary malignancies associated with a germline mutation of the p53 tumorsuppressor gene. Int J Clin Oncol, 13: 78-82, 2008.

6.

Kimura, J., Nguyen, S. T., Liu, H., Taira, N., Miki, Y.,* and Yoshida, K. A functional genome-wide RNAi screen identifies TAF1 as a regulator for apoptosis in response to genotoxic stress. Nucleic Acids Res, 36: 5250-9, 2008. *Corresponding author

7.

Komatsu, A., Nagasaki, K., Fujimori, M., Amano, J., and Miki, Y. Identification of novel deletion polymorphisms in breast cancer. Int J Oncol, 33: 261-70, 2008.

8.

Nihira, K., Taira, N., Miki, Y.,* and Yoshida, K. TTK/Mps1 controls nuclear targeting of c-Abl by 308 Annual Report 2008 14-3-3-coupled phosphorylation in response to oxidative stress. Oncogene, 27: 7285-95, 2008. *Corresponding author

9.

Oku, Y., Shimoji, T., Takifuji, K., Hotta, T., Yokoyama, S., Matsuda, K., Higashiguchi, T., Tominaga, T., Nasu, T., Tamura, K., Matsuura, M., Miyata, S., Kato, Y., Yamaue, H., and Miki, Y. Identification of the molecular mechanisms for dedifferentiation at the invasion front of colorectal cancer by a gene expression analysis. Clin Cancer Res, 14: 7215-22, 2008.

10.

Shinagawa, H., Miki, Y.,* and Yoshida, K. BRCA1- mediated ubiquitination inhibits topoisomerase II alpha activity in response to oxidative stress. Antioxid Redox Signal, 10: 939-49, 2008. *Corresponding author

11.

Sugano, K., Nakamura, S., Ando, J., Takayama, S., Kamata, H., Sekiguchi, I., Ubukata, M., Kodama, T., Arai, M., Kasumi, F., Hirai, Y., Ikeda, T., Jinno, H., Kitajima, M., Aoki, D., Hirasawa, A., Takeda, Y., Yazaki, K., Fukutomi, T., Kinoshita, T., Tsunematsu, R., Yoshida, T., Izumi, M., Umezawa, S., Yagata, H., Komatsu, H., Arimori, N., Matoba, N., Gondo, N., Yokoyama, S., and Miki, Y. Crosssectional analysis of germline BRCA1 and BRCA2 mutations in Japanese patients suspected to have hereditary breast/ovarian cancer. Cancer Sci, 99: 1967- 76, 2008.

12.

Tanaka, S., Arii, S., Yasen, M., Mogushi, K., Su, N. T., Zhao, C., Imoto, I., Eishi, Y., Inazawa, J., Miki, Y., and Tanaka, H. Aurora kinase B is a predictive factor for the aggressive recurrence of hepatocellular carcinoma after curative hepatectomy. Br J Surg, 95: 611-9, 2008.

13.

Tomiyoshi, G., Nakanishi, A., Takenaka, K., Yoshida, K., and Miki, Y. Novel BRCA2-interacting protein BJ-HCC- 20A inhibits the induction of apoptosis in response to DNA damage. Cancer Sci, 99: 747-54, 2008.