1.

Shimizu T, Kishida T, Hasegawa U, Ueda Y, Imanishi J, Yamagishi H, Akiyoshi K, Otsuji E, Mazda O. Nanogel DDS enables sustained release of a cytokine for tumor immunotherapy. Biochem Biophys Res Commun 367: 330-335, 2008.

2.

Nomura SM, Kondoh S, Asayama W, Asada A, Nishikawa S, Akiyoshi K. Direct preparation of giant proteo-liposomes by in vitro membrane protein synthesis. J Biotechnol 133: 190-195, 2008.

3.

Kageyama S, Kitano S, Hirayama M, Nagata Y, Imai H, Shiraishi T, Akiyoshi K, Scott A, Murphy R, Hoffman E, Old L, Katayama N, Shiku H. Humoral immune responses in patients vaccinated with 1-146 HER2 protein complexed with cholesteryl pullulan nanogel （CHP-HER2）. Cancer Sci 99: 601-607, 2008.

4.

Iwata R, Iwasaki Y, Akiyoshi K. Covalent immobilization of antibody fragments on well-defined polymer brushes via site-directed method. Colloid Surf B-Biointerfaces 62: 288-298, 2008.

5.

Asayama W, Sawada S, Taguchi H, Akiyoshi K. Comparison of Refolding Activities between Nanogel Artificial Chaperone and GroEL Systems. Int J Biol Macromol 42: 241-246, 2008.

6.

Toita S, Hasegawa U, Koga H, Sekiya I, Muneta T, Akiyoshi K. Protein-conjugated QD effectively delivered into living cells by a cationic nanogel. J Nanosci Nanotechnol 8: 1-7, 2008.

7.

Ayame H, Morimoto N, Akiyoshi K. Self-assembled cationic nanogels for intracellular protein delivery system. Bioconjugate Chem 19: 882-890, 2008.

8.

Morimoto N, Ohki T, Kurita K, Akiyoshi K. Thermoresponsive hydrogels with nanodomains: rapid shrinking of nanogel-crosslinking hydrogel of poly（ N-isopropyl acrylamide） Macromol Rapid Commun 29: 672-676, 2008.

9.

Kudo H, Yagi T, Chu MX, Saito H, Morimoto M, Iwasaki Y, Akiyoshi K, Mitsubayashi K. Glucose sensor using phospholipid polymer-based enzyme immobilization method. Anal Bioanal Chem 391: 1269-1274, 2008.

10.

Morimoto N, Qiu XP, Winnik FM, Akiyoshi K. Dual Stimuli-Responsive Nanogels by Self-Assembly of Polysaccharides Lightly Grafted with Thiol-Terminated Poly（N-isopropylacrylamide） Chains. Macromolecules 41: 5985-5987, 2008.

11.

Iwasaki Y, Takami U, Sawada S, Akiyoshi K. Interfacing biomembrane mimetic polymer surfaces with living cells-Surface modification for reliable bioartificial liver. Appl Surf Sci 255: 523-528, 2008.

12.

Yamane S, Sasaki Y, Akiyoshi K. Siloxane-crosslinked Polysaccharide Nanogels for Potential Biomedical Applications. Chem Lett 37: 1282-1283, 2008.

13.

Morimoto N. Obeid R. Yamane S. Winnik F. M. Akiyoshi K. Composite Nanomaterials by Self-assembly and Controlled Crystallization of Poly（2-isopropyl-2- oxazoline）-Grafted Polysaccharide. Soft Matter in press.

14.

Morimoto N. Ogino N. Narita T. Akiyoshi K. Enzymeresponsive artificial chaperone system with amphiphilic amylose primer. J. Biotech. in press.

15.

Yamane S, Sugawara A, Watanabe A, Akiyoshi K. Hybrid nanoapatitby polysaccharide nanogel-templated mineralization, J. Bioactive and Compatible Polym, in press.

16.

Yamane S, Sugawara A, Sasaki Y, Akiyoshi K. Nanogelcalcium phosphate hybrid nanoparticles with negative or positive charges for potential biomedical applications. Bull. Chem. Soc. Jpn. in press

17.

◎Alles N. Soysa N.S. Mian A. H. Tomomatsu N. Saito H. Baron R. Morimoto N. Aoki K. Akiyoshi K. Ohya K. Polysaccharide nanogel delivery of a TNF-a and RANKL antagonist peptide allows systemic prevention of bone loss. Eur. J. Pharma. Sci. in press.

18.

◎Ozawa Y. Sawada S. Morimoto N. Akiyoshi K. Selfassembeld nanogel of hydrophobized dendritic dextrin for protein delivery. Macromol. Biosci. in press.

19.

Kobayashi H. Katakura O. Morimoto N. Akiyoshi K. Kasugai S. Effects of cholesterol-bearing pullulan（ CHP） -nanogels in combination with prostaglandin E1 on wound healing. J. Biomed. Mater. Res. B. in press.

20.

◎Miyai K, Yoneda M , Hasegawa U , Toita S , Izu Y, Hemmi H, Hayata T, Ezura Y, Mizutani S, Miyazono K , Akiyoshi K, Yamamoto T, Noda M, ANA deficiency enhances BMP-induced ectopic bone formation via transcriptional events, J. Biological Chem. in press

21.

◎Hayashi C, Hasegawa U, Saita Y, Hemmi H, Hayata T, Nakashima K, Ezura Y, Amagasa T, Akiyoshi K, Noda M, Osteoblastic bone formation is induced by using nanogel-crosslinking hydrogel as novel scaffold for bone growth factor, J. Cell. Phys. in press