1.

Chen YW, Umeda M, Nagasawa T, Takeuchi Y, Huang Y, Inoue Y, Imai T, Izumi Y, Ishikawa I. Periodontitis may increase that risk of peripheral arterial disease. Eur J Vas Endovasc Surg 35:153-158, 2008.

2.

Eguchi T, Koshy G, Umeda M, Iwanami T, Suga J, Nomura Y, Kawanami M, Ishikawa I. Micro changes in patients with acute periodontal abscess after treatment detected by Padotest. Oral Dis 14;180-184, 2008.

3.

Ishikawa, A. Aoki, A.A. Takasaki, K. Mizutani, K.M. Sasaki, Y. Izumi, Applocation of lasers in periodontics: true innovation or myth ?, Periodontol 2000, 49: 1-37, 2009.

4.

Iwasaki K, Komaki M, Mimori K, Leon E, Izumi Y, Ishikawa I. IL-6 induces osteoblastic differentiation of periodontal ligament cells. J Dent Res 87（10）:937-942, 2008.

5.

Iwaya Y, Machigashira M, Kanbara K, Miyamoto M, Noguchi K, Izumi Y, Ban S. Surface properties and biocompatibility of acid-etched titanium. Dent Mater J 27:415-421, 2008

6.

Kadomatsu H, Matsuyama T, Yoshimoto T, Negishi Y, Sekiya H, Yamamoto M, Izumi Y. Injectable growth/ differentiation factor-5/ recombinant human collagen composite induces endochondral ossification via sox9 expression and angiogenesis in murine calvariae. J. Periodontal Res, 43: 483-489, 2008.

7.

Kamiyama K, Arakawa S, Takahashi M, Chiba K, Yamami N, Yagishita K, Mano Y. Effects of nano-bubble water on periodontal disease. The Jpn J Hyperbaric and Undersea Med 43:53-60, 2008.

8.

Kawakatsu N, Oda S, Kinoshita A, Kikuchi S, Tsuchioka H, Akizuki T, Hayashi C, Kokubo S, Ishikawa I, Izumi Y.: Effect of rhBMP-2 with PLGA/gelatin sponge type （PGS） carrier on alveolar ridge augmentation in dogs. Journal of Oral Rehabilitation 35: 647-655, 2008.

9.

Kitamura M, Nakashima K, Kowashi Y, Fujii T, Shimauchi H, Sasano T, Furuuchi T, Fukuda M, Noguchi T, Shibutani T, Iwayama Y, Takashiba S, Kurihara H, Ninomiya M, Kido J, Nagata T, Hamachi T, Maeda K, Hara Y, Izumi Y, Hirofuji T, Imai E, Omae M, Watanuki M, Murakami S. Periodontal tissue regeneration using fibroblast growth factor -2: Randomized controlled phase II clinical trial. PLos ONE 3（7）, 2008: e2611. Doi10.1371/j.pone.0002611.

10.

Kubota T, Inoue Y, Iwai T, Kurihara N, Huang Y, Umeda M. Arterial thrombosis after intravenous infusion of oral bacterium in a rat model. Ann Vasc Surg 22:412-416, 2008.

11.

Li X, Iwai T, Nakamura H, Inoue Y, Chen Y, Umeda M, Suzuki H. An ultrastructural study of Porphyromonas gingivalis-induced platelet aggregation. Thromb Res 122:810-819, 2008.

12.

Maruyama H, Aoki A, Sasaki KM, Takasaki AA, Iwasaki K, Ichinose S, Oda S, Ishikawa I, Izumi Y. The effect of chemical and/or mechanical conditioning on the Er:YAG laser treated root cementum: analysis of surface morphology and periodontal ligament fibroblast attachment. Lasers Surg Med 40（3）:211-222, 2008.

13.

Matsuyama, T., Tokuda, M., Izumi, Y., Significance of thrombomodulin release from gingival epithelial cells in periodontitis patients. J Periodontal Res 43: 379-385, 2008.

14.

Morimoto, Y., Kawahara, K-I., Tancharoen, S., Kikuchi, K., Matsuyama, T., Hashiguchi, T., Izumi, Y., Maruyama, I., Tumor necrosisi factor-alpha stimulates gingival epithelial cells to release high mobility-group box 1., J Periodontal Res. 43: 76-83, 2008.

15.

Nakamura N, Yoshida M, Umeda M, Huang Y, Kitajima S, Inoue Y, Ishikawa I, Iwai T. Extended exposure of lipopolysaccharide fraction from Porphyromonas gingivalis facilitates mononuclear cell adhesion to vascular endothelim via Toll-like receptor-2 dependent mechanism. Atherosclerosis 196:59-67, 2008.

16.

Shirakata Y, Setoguchi T, Machigashira M, Matsuyama T, Furuichi Y, Hasegawa K, Nakamura T, Izumi Y. Comparison of injectable calcium phosphate bone cement grafting and open flap debridement in periodontal intrabony defects: A randomized clinical trial. J. Periodontol. 79: 25-32, 2008.

17.

Soejima H, Oe Y.,Nakayama H, Matsuo K, Fukunaga T, Sugamura K, Kawano H, Sugiyama S, Shinohara M, Izumi Y, Ogawa H. Periodontal status and Prevotella intermedia antibody in acute coronary syndrome. Int J Cardiol, 2008, doi: 10,1016/j.ijcard.2008.05.057.

18.

Sogabe N, Oda K, Nakamura H, Orimo H, Watanabe H, Hosoi T, Goseki-Sone M. Molecular effects of the tissue-nonspecific alkaline phosphatase gene polymorphism（ 787T > C） associated with bone mineral density. Biomed Res 29（4）:213-219, 2008.

19.

Takeuchi, H., Setoguchi, T., Machigashira, M., Kanbara, K, Izumi, Y., Hydrogen sulfide inhibits cell proliferation and induces cell cycle arrest via an elevated p21Cip1 level in Ca9-22 cells., J Periodontal Res. 43: 90-95, 2008.

20.

Tancharoen S, Matsuyama T, Abeyama K, Matsushita K, Kawahara K, Sangalungkarn V, Tokuda M, Hashiguchi T, Maruyama I, Izumi Y. The role of water channel aquaporin 3 in the mechanism of TNF-alpha-mediated proinflammatory events: Implication in periodontal inflammation. J Cell Physiol, 217: 338-349, 2008.

21.

◎ Ushida Y, Koshy G, Kawashima Y, Kiji M, Umeda M, Nitta H, Nagasawa T, Ishikawa I, Izumi Y. Changes of serum IL-6, CRP, and thrombomodulin levels under periodontal ultrasonic debridement. J Clin Periodontol 35:969-975, 2008.

22.

Wang D, Nagasawa T, Chen Y, Ushida Y, Kobayashi H, Takeuchi Y, Umeda M, Izumi Y. Molecular mimicry of Aggregatibacter acttinomycetemcomitans with β 2 glycoprotein 1. Oral Microbiol Immnol 23:401- 405, 2008.

23.

Y. Oe, H. Soejima, H. Nakayama, T. Fukunaga, K. Sugamura, H. Kawano, S. Sugiyama, K. Matsuo, M. Shinohara, Y. Izumi, H. Ogawa, Significant Association Between Score of Periodontal Disease and Coronary Artery Disease. Heart and Vessels（ in press）

24.

Yoshino T, Aoki A, Oda S, Takasaki AA, Mizutani K, Sasaki KM, Kinoshita A, Watanabe H, Ishikawa I, Izumi Y. Long-term histological analysis of bone tissue alteration and healing following Er:YAG laser irradiation in comparison with electrosurgery. J Periodontol（ in press）

25.

Miyazaki H, Kato J, Watanabe H, Harada H, Kakizaki H, Tetsumura A, Sato A, Omura K. Intralesional laser treatment of voluminous vascular lesions in the oral cavity. Oral Surg Oral Med Oral Path, Oral Rad Endodont 107（2）:164-172, 2009.

26.

Miyazaki H, Kato J, Kakizaki H, Nagata T, Uetake H, Okudera H, Watanabe H, Hashimoto K, Omura K. Submucosal glycerol injection assisted laser surgical treatment of oral lesions. Lasers Med Sci 24:13-19, 2009.