東京医科歯科大学 グローバルCOEプログラム 歯と骨の分子疾患科学 国際教育研究拠点〜デント・メドミクスのインテリジェンスパブ

Publication

Masaki Noda, M.D., Ph.D. 野田政樹

1.

○Miyai K, Yoneda M, Hasegawa U), Toida S, Izu Y, Hiroaki H, Hayata T, Ezura Y, Mizutani S, Miyazono K, Akiyoshi K, Yamamoto T, Noda M. ANA deficiency enhances BMP-induced ectopic bone formation via transcriptional events. Journal of Biological Chemistry; 2009( in press)

2.

○Izu Y, Mizoguchi F, Kawamata A, Hayata T, Nakamoto T, Nakashima K, Inagami T, Ezura Y, Noda M. Angiotensin II type 2 receptor blockade increases bone mass. Journal of Biological Chemistry 284:4857-64; 2009

3.

○Ono N., Nakashima K., Rittling S.R., Schipani E., Hayata T., Ezura Y., Soma K., Denhardt D.T., Kronenberg H.M., Noda M. Osteopontin Negatively Regulates parathyroid hormone receptor signaling in osteoblasts Journal of Biological Chemistry 283:19400-19409, 2008

4.

○ Kawamata A., Izu Y., Yokoyama H., Hayata T., Amagasa T., Wagner E.F., Nakashima K., Ezura Y., Noda M. JunD suppresses bone formation and contributes to low bone mass induced by estrogen depletion. Journal of Cellular Biochemistry. 103:1037-45, 2008

5.

○ Mizoguchi F., Mizuno A., Hayata T., Nakashima K., Heller S., Ushida T., Sokabe M., Miyasaka N., Suzuki M., Ezura Y., Noda M. Transient Receptor Potential Vanilloid 4 Deficiency Suppresses Unloading-Induced Bone Loss. Journal of Cellular Physiology. 216:47-53, 2008

6.

○ Hayashi C, Hasegawa U, Saita Y, Hemmi H, Hayata T, Nakashima K, Ezura Y, Amagasa T, Akiyoshi K, Noda M. Osteoblastic Bone Formation Is Induced by Using Nanogel-Crosslinking Hydrogel as Novel Scaffold for Bone Growth Factor. Journal of Cellular Physiology; 2009 (in press)

7.

○ Hayata T., Nakamoto T., Ezura Y., Noda M. Ciz, a transcription factor with a nucleocytoplasmic shuttling activity, interacts with C-propeptides of type I collagen Biochemical and Biophysical Research Communications. 368:205-10, 2008

8.

○ Chung C.J., Soma K., Rittling S.R., Denhardt D.T., Hayata T., Nakashima K., Ezura Y., Noda M. OPN deficiency suppresses appearance of odontoclastic cells and resorption of the tooth root induced by experimental force application. Journal of Cellular Physiology 214:614- 20, 2008

9.

Suzuki H., Amizuka N., Oda K., Noda M., Ohshima H., Maeda T., Involvement of the klotho protein in dentin formation and mineralization. Anatomical Record 291:183- 190, 2008

10.

Suzuki H., Amizuka N., Oda K., Noda M., Ohshima H., Maeda T. Histological and elemental analyses of impaired bone mineralization in klotho-deficient mice. J Anat. 212:275-85, 2008

11.

○ Nakamoto T., Seo S., Sakai R., Kato T., Kutsuna H., Kurokawa M., Noda M., Miyasaka N., Kitagawa S. Expression and tyrosine phosphorylation of Crk associated substrate lymphocyte type( Cas-L) protein in human neutrophils. Journal of Cellular Biochemistry;105:121-128, 2008

12.

Ajima R., Akiyama T., Usui M., Yoneda M., Yoshida Y., Nakamura T., Minowa O., Noda M., Tanaka S., Noda T., Yamamoto T. Osteoporotic bone formation in mice lacking tob2; involvement of Tob2 in RANK ligand expression and osteoclasts differentiation. FEBS Lett.; 582:1313-8, 2008

13.

Tazaki T, Miyazaki K, Hiyama E, Nakamoto T, Sakai R, Yamasaki N, Honda Z, Noda M, Miyasaka N, Sueda T, Honda H. Functional analysis of Src homology 3-encoding exon( exon 2) of p130Cas in primary fibroblasts derived from exon 2-specific knockout mice. Genes Cells;13:145-57, 2008

14.

Hemmi H, Idoyaga J, Suda K, Suda N, Kennedy K, Noda M, Aderem A, Steinman RM, A new Trem family member, Treml4, binds to dead cells and is a DAP12 linked marker for subsets of mouse macrophages and dendritic cells. Journal of Immunology; 182:1278-86, 2008

15.

○Ezura Y, Koga H, Muneta T, Sekiya I, Noda M. Methylation status of CpG-islands in the promoter regions of signature genes during chondrogenesis of human synovium-derived mesenchymal stem cells. Arthritis & Rheumatism; 2009( in press)