Hidenori ICHIJO      Selected Papers      Review articles      papers

    1. Shiizaki, S., Naguro, I. and Ichijo, H. Activation mechanisms of ASK1 in response to various stresses and its significance in intracellular signaling.
      Adv. Biol. Regul., (review article), pii: S2212-4926(12)00090-5. doi: 10.1016/j.jbior.2012.09.006.

    2. Hayakawa, R., Hayakawa, T., Takeda, K. and Ichijo, H. Therapeutic targets in the ASK1-dependent stress signalling pathways.
      Proc. Jpn. Acad. Ser. B: Phys. Biol. Sci., (review article), 88, 434-453 (2012).

    3. Kanamaru, Y., Sekine S., Ichijo, H. and Takeda, K. The Phosphorylation-Dependent Regulation of Mitochondrial Proteins in Stress Responses.
      J. Signal Transduct. (review article), 2012, 12 (2012),

    4. Soga, M., Matsuzawa, A., Ichijo, H. Oxidative Stress-Induced Diseases via the ASK1 Signaling Pathway.
      Int. J. Cell Biol., (review article),2012, 439587 (2012).

    5. Runchel, C., Matsuzawa, A. and Ichijo, H. MAPKs in mammalian oxidative stress responses.
      Antioxid. Redox Signal. (review article), 15, 205-218 (2011).

    6. Takeda, K., Naguro, I., Nishitoh, H.,Matsuzawa, A. and Ichijo, H. Apoptosis signaling kinases: from stress response to health outcomes.
      Antioxid. Redox Signal. (review article), 15, 719-761 (2011).

    7. Matsuzawa, A., Takeda, K. and Ichijo, H. ASK1: Molecule Pages,
      UCSD-Nature Signaling Gateway, (review article) (2010) (doi:10.1038/mp.a002816.01).

    8. Katagiri, K., Matsuzawa, A. and Ichijo, H. Regulation of Apoptosis Signal-regulating Kinase 1 in redox signaling.
      Methods in Enzymology, (review article) 474, 277-288 (2010).

    9. Shimizu, Y., Naguro, I., Nishitoh, H. and Ichijo, H. ER stress-induced cell death and inflammatory signaling: a therapeutic insight into intractable diseases.
      Endoplasmic Reticulum Stress and Human Disease, (review article), in press.

    10. Nishitoh, H., Kadowaki H.,,Takeda, K. and Ichijo, H. ER Quality Control, ER Stress-Induced Apoptosis, and Neurodegenerative Diseases
      Protein Misfolding Disorders: A Trip into the ER, (review article) 94-102 (2009).

    11. Homma, K., Katagiri, K., Nishitoh, H. and Ichijo, H. Targeting ASK1 in ER stress-related Neurodegenerative Diseases.
      Expert Opinion on Therapeutic Targets, (review article), 13, 653-664 (2009).

    12. Hatanaka, R., Sekine, Y., Hayakawa, T., Takeda, K. and Ichijo, H. Signaling pathways in invertebrate immune and stress response.
      Invertebrate Survival Journal, (review article), 6, 32-43 (2009).

    13. Hattori, K., Naguro, I., Runchel, C. and Ichijo, H. The roles of ASK family proteins in stress responses and diseases.
      Cell Communication and Signaling, (review article), 7, 9 (2009).

    14. Maruyama, J., Naguro, I., Takeda, K. and Ichijo, H. Stress-Activated MAP Kinase Cascades in Cellular Senescence.
      Curr. Med. Chem., (review article), 16, 1229-1235 (2009).

    15. Yamauchi, S., Noguchi, T. and Ichijo, H. Molecular Mechanism of Reactive Oxygen Species-dependent ASK1 Activation in Innate Immunity.
      Immune Network, (review article), 8, 1-6 (2008).

    16. Matsuzawa, A. and Ichijo, H. Redox control of cell fate by MAP kinase: physiological roles of ASK1-MAP kinase pathway in stress signaling.
      Biochim. Biophys. Acta., (review article), 1780, 1325-1336 (2008).

    17. Takeda, K., Noguchi, T., Naguro, I. and Ichijo, H. Apoptosis Signal-regulating Kinase 1 (ASK1) in stress and immune response.
      Annu. Rev. Pharmacol. Toxicol., (review article), 48, 199-225 (2008).

    18. Fujisawa, T., Takeda, K and Ichijo, H. ASKfamily proteins in stress response and disease.
      Mol. Biotechnol., (review article), 37, 13-18 (2007).

    19. Murakami, S., Noguchi, T., Takeda, K. and Ichijo, H. Stress signaling in cancer.
      Cancer Sci., (review article), 98, 1521-1527 (2007).

    20. Nagai, H., Noguchi, T., Takeda, K.and Ichijo, H. Pathophysiological Roles of ASK1-MAP Kinase Signaling Pathways.
      J. Biochem. Mol. Biol., (review article), 40, 1-6 (2007).

    21. Fujino, G., Noguchi, T., Takeda, K. and Ichijo, H. Thioredoxin and protein kinases in redox signaling.
      Semin. Cancer Biol., (review article), 16, 427-735 (2006).

    22. Takeda, K., Noguchi, T. and Ichijo, H. ASK1 Signalosome: a Signaling Complex Essential for Cellular Stress Responses.
      J. Oral Biosci, (review article), 48, 7-11 (2006) .

    23. Hayakawa, T., Matsuzawa, A., Noguchi, T., Takeda, K. and Ichijo, H. The ASK1-MAP kinase pathways in the immune and stress responses.
      Microbes Infect., (review article), 8, 1098-1107(2006).

    24. Sekine, Y., Takeda, K. and Ichijo, H. The ASK1-MAP kinase signaling in ER stress and neurodegenerative diseases.
      Curr. Mol. Med., (review article), 6, 87-97 (2006).

    25. Matsuzawa, A. and Ichijo, H. Stress-responsive protein kinases in redox-regulated apoptosis signaling.
      Antioxid. Redox Signal, (review article), 7, 472-481 (2005).

    26. Matsukawa, J., Matsuzawa, A., Takeda, K. and Ichijo, H. Functions of MAP Kinase cascades: The ASK1-MAP Kinase cascades in mammalian stress response.
      J. Biochem. (review article), 136, 261-265 (2004).

    27. Naguro, I., Adachi-Akahane, S. and Ichijo, H. Calcium signaling via voltage-dependent L-type Ca2+ channels.
      Signal Transduction (review article), 4, 195-205 (2004).

    28. Kadowaki, H., Nishitoh, H. and Ichijo, H. Survival and apoptosis signals in ER stress: the role of protein kinases.
      J. Chem. Neuroanat. (review article), 28, 93-100 (2004).

    29. Oberst, A., Baehrecke, E., Mehmet, H., Ichijo, H. and Gupta, S. A place to die for: apoptosis in cancer and infection, Capri 2002.
      Cell Death Differ. (review article), 10, 393-395 (2003).

    30. Takeda K, Matsuzawa A, Nishitoh H and Ichijo, H. Roles of MAPKKK ASK1 in Stress-Induced Cell Death.
      Cell Struct Funct. (review article), 28, 23-29 (2003).

    31. Matsuzawa, A., Nishitoh, H., Takeda, K. and Ichijo, H. "MAP Kinases in Redox Signaling" in "Signal Transduction by Reactive Oxygen and Nitrogen Species: Pathways and Chemical Principles" ed. by Forman, HJ., Kluwer Academic (review article), 223-236 (2003).

    32. Takeda, K. and Ichijo, H. Neuronal p38 MAPK signalling: an emerging regulator of cell fate and function in the nervous system.
      Genes Cells (review article), 7, 1099-1111 (2002).

    33. Matsuzawa, A., Nishitoh, H., Tobiume, K., Takeda, K. and Ichijo, H.  Physiological roles of ASK1-mediated signal transduction in oxidative stress- and endoplasmic reticulum stress-induced apoptosis: advanced findings from ASK1 knockout mice.
      Antioxid. Redox Signal(review article), 4, 415-425 (2002).

    34. Matsuzawa, A. and Ichijo, H. Molecular Mechanisms of the Decision between Life and Death: Regulation of Apoptosis by Apoptosis Signal-Regulating Kinase 1.
      J. Biochem.(review article), 130, 1-8 (2001).

    35. Ichijo, H.  From receptors to stress-activated MAP kinases.
      Oncogene (review article), 18, 6087-6093 (1999).

    36. ten Dijke, P., Franzen, P., Yamashita, H., Ichijo, H., Heldin, C.-H., and Miyazono, K. Serine/threonine kinase receptors.
      Prog. Growth Factor Res. (review article), 5, 55-72 (1994).

    37. Miyazono, K., ten Dijke, P., Ichijo, H. and Heldin, C.-H. Receptors for transforming growth factor-β.
      Adv. Immunol. (Dixon,F.J. ed., Academic Press,Inc.), 55, 181-220 (1994).

    38. Miyazono, K., Ichijo, H. and Heldin, C.-H. Transforming growth factor-β: latent forms, binding proteins and receptors.
      Growth Factors (review article), 8, 11-22 (1993).