主な業績リスト

Goto, T., Sato, A., Shimizu, M., Adachi, S., Satoh, K., Iemura, S., Natsume, T. and Shibuya, H. (2013).  IQGAP1 protein regulates nuclear localization of β-catenin via importin-β5 in Wnt signaling.  J Biol Chem. 288, 36351-36360.

Sato, A. and Shibuya, H. (2013). WNK Signaling Is Involved in Neural Development via Lhx8/Awh Expression. PLoS One 8, e55301.

Ohnishi, E., Goto, T., Sato, A., Kim, M., Iemura, S., Ishitani, T., Natsume, T., Ohnishi, J. and Shibuya, H. (2010). NLK, an essential effector of anterior formation, functions downstream of p38 MAP kinase. Mol. Cell. Biol. 30, 675-683.

Satoh, K., Ohnishi, J., Sato, A., Takeyama, M., Iemura, S., Natsume, T. and Shibuya, H. (2007). NLK-MEF2A signaling regulates anterior formation in Xenopus development. Mol. Cell. Biol. 27, 7623-7630.

Yamada, M., Ohnishi, J., Ohkawara, B., Iemura, S., Satoh, K., Hyodo-Miura, J., Kawachi, K., Natsume, T. and Shibuya, H. (2006). NARF, an NLK-associated RING finger protein regulates the ubiquitylation and degradation of TCF/LEF. J. Biol. Chem. 281, 20749-20760.

Moriguchi, T., Urushiyama, S., Hisamoto, N., Iemura, S., Uchida, S., Natsume, T., Matsumoto, K. and Shibuya, H. (2005). WNK1 regulates phosphorylation of cation-chloride-coupled cotransporters via the STE20-related kinases, SPAK and OSR1. J. Biol. Chem. 280, 42685-42693.

Ohkawara, B., Shirakabe, K., Hyodo-Miura, J., Matsuo, R., Ueno, N., Matsumoto, K. and Shibuya, H. (2004). Role of the TAK1-NLK-STAT3 pathway in TGF-β-mediated mesoderm induction. Genes Dev. 18,381-386.

Nishita, M. et al. (2000). Interaction between Wnt and TGF-β signalling pathways during formation of Spemann's organizer. Nature 403, 781-785.

Shibuya, H. et al. (1998). Role of TAK1 and TAB1 in BMP signaling in early Xenopus development. EMBO J. 17, 1019-1028.

Shibuya, H. et al. (1996). TAB1: An activator of the TAK1 MAPKKK in TGF-β signal transduction. Science 272, 1179-1182.

Yamaguchi, K. et al. (1995). Identification of a member of the MAPKKK family as a potential mediator of TGF-β signal transduction. Science 270, 2008-2011.


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