Section of Environmental Parasitology,
Department of International Health Development,
Division of Public Health,
Graduate School of Tokyo Dedical and Dental University






Recent Publications
  1. Chen R, Lu S, Lou D, Lin A, Zeng X, Ding Z, Wen L, Ohta N, Wang J, Fu C. Evaluation of a rapid ELISA technique for detection of circulating antigens of Toxoplasma gondii. Microbiology and Immunology, 52:180-7, 2008.

  2. Jin Z, Akao N, Ohta N. Prolactin evokes lactational transmission of larvae in mice infected with Toxocara canis. Parasitology International. 2008; 57(4): 495-8.

  3. Jin ZF, Akao N, Nobuta T, Ohta N. An improved method for recovery of muscle-stage larvae from mice infected with Toxocara canis. Journal of Parasitology. 2008;94(5):1164-5.

  4. Maeda T, Yamada H, Akao N, Iga M, Endo T, Koibuchi T, Odawara T, Iwamoto A, Fujii T. Unusual radiological findings of Fasciola hepatica infection with a huge cystic and multilocular lesions. Internal Medicine. 2008;47:449-52.

  5. Yoshikawa M, Nishiofuku M, Moriya K, Ouji Y, Ishizaka S, Kasahara K, Mikasa K, Hirai T, Mizuno Y, Ogawa S, Maruyama H, Akao N. A familial case of visceral toxocariasis due to consumption of raw bovine liver. Parasitology International. 2008;57(4):525-9.

  6. Yoshikawa M, Ouji Y, Nishiofuku M, Moriya K, Kasahara K, Mikasa K-i, Mizuno Y, Ogawa S, Akao N. Visceral toxocariasis from regular consumption of raw cow liver. Internal Medicine. 2008;47:1289-90.

  7. Review Article
    Zhou X, Ohta N, Ultzinger J, Berquist R, Olveda RM. RNAS(+): a win-win collaboration to combat neglected tropical diseases in Southeast Asia. Parasitology International, 57: 243-245, 2008.

  1. Akao N, Ohta N. Toxocariasis in Japan. Parasitology International. 2007;56(2):87-93. Sugita S, Shimizu N, Kawaguchi T, Akao N, Morio T, Mochizuki M. Identification of human herpesvirus 6 variant A in a patient with ocular toxocariasis. Archives of Ophthalmology. 2007;125:1426-1427.

  2. Cho S, Egami M, Ohnuki H, Saito Y, Chinone S, Shichinohe K, Suganuma M, Akao N. Migration behaviour and pathogenesis of five Ascarid parasites, Toxocara canis, Baylisascaris procyonis, B. transfuga, Ascaris suum, and A. lumbricoides in the Mongolian gerbil, Meriones unguiculatus. Journal of Helminthology 2007;81:43-47.

  3. Hayashi E, Ohta N, Yamamoto H.: Syndrome of inappropriate secretion of antidiuretic hormone associated with strongyloidiasis. Southeast Asian Journal of Tropical Medicine & Public Health. 38(2):239-46, 2007.

  4. s Ohta N, Waikagul J. : Disease burden and epidemiology of soil-transmitted helminthiases and schistosomiasis in Asia: the Japanese perspective. Trends in Parasitology. 23:30-5, 2007.

  5. Suzuki M, Ohta N, Min WP, Matsumoto T, Min R, Zhang X, Toida K, Murakami S. : Immunotherapy with CpG DNA conjugated with T-cell epitope peptide of an allergenic Cry j 2 protein is useful for control of allergic conditions in mice. International Immunopharmacology. 7:46-54, 2007.

  6. Kojima S, Aoki Y, Ohta N, Tateno S, Takeuchi T. School-health-based parasite control initiatives: extending successful Japanese policies to Asia and Africa. Trends in Parasitology. 23:54-7, 2007.

  7. Suzuki M, Matsumoto T, Ohta N, Min WP, Murakami S.: Intranasal CpG DNA therapy during allergen exposure in allergic rhinitis. Otolaryngol Head Neck Surg. 136:246-51, 2007.

  8. Lu S, Suzuki T, Iizuka N, Ohshima S, Yabu Y, Suzuki M, Wen L, Ohta N. : Trypanosoma brucei vacuolar protein sorting 41 (VPS41) is required for intracellular iron utilization and maintenance of normal cellular morphology. Parasitology. 134:1639-47, 2007

  1. Lu SH, Kumagai T, Ai QH, Yan XL, Ohmae H, Yabu Y, Li, SW, Wen LY, Maruyama H, Ohta N. Evaluation of the anthelmintic effects of artesunate against experimental Schistosoma mansoni infection in mice using different treatment protocols. Parasitology International, 55: 63-68, 2006

  2. Yabu Y, Suzuki T, Nihei C, Minagawa N, Hosokawa T, Nagai K, Kita K, Ohta N. Chemotherapeutic efficacy of ascofuranone in Trypanosoma vivax-infected mice without glycerol. Parasitology International, 55:39-43, 2006.

  3. Maruyama H, Nishimaki A, Takuma Y, Kurimoto M, Suzuki T, Sakatoku Y, Ishikawa M, Ohta N. Successive changes in tissue migration capacity of developing larvae of an intestinal nematode, Strongyloides venezuelensis. Parasitology, 132:411-418, 2006.

  4. Suzuki M, Itoh M, Ohta N, Nakamura Y, Moriyama A, Matsumoto T, Ohashi T, Murakmi S. Blocking of protease allergens with inhibitors reduces allergic responses in allergic rhinitis and other allergic diseases. Acta Otolaryngology, 126:746-751, 2006.

  5. Nakamura-Uchiyama F, Tokunaga Y, Suzuki A, Akao N, Hiromatsu K, Shigemi H, Nawa Y. A case of Ascaris suum visceral larva migrans diagnosed by using A. suum larval excretory-secretory (ES) antigen. Scan J Inf Dis. 2006;38:221-4.

  6. Morimatsu Y, Akao N, Akiyoshi H, Kawazu T, Okabe Y, Aizawa H. Case Reports: A familial case of visceral larva migrans after ingestion of raw chicken livers: The specific antibody in bronchoalveolar lavage fluid. American Journal of Tropical Medicine and Hygine. 2006;75:303-6.

  1. Hayashi E, Tuda J, Imada M, Akao N, Fujita K. The high prevalence of asymptomatic Toxocara infection among school children in Manado, Indonesia. Southesat Asian Journal of Public Health. 2005;36:1399-1406.

  2. Suzuki T, Joko T, Akao N, Ohashi Y. Following the migration of a Toxocara larva in the retina by optical coherence tomography and fluorescein angiography. Jpn J Ophthalmol. 2005;49:159-161.

  3. Satou T, Horiuchi A, Akao N, Koike K, Fujita K, Nikaido T. Toxocara canis: Search for a potential drug amongst beta-carboline alkaloids-in vitro and mouse studies. Exp Parasitol. 2005;110:134-139.

  4. Sato H, Une Y, Kawakami S, Osanai A, Kamiya H, Akao N, Furuoka H. Fatal Baylisascaris procyonis larva migrans in a colony of Japanese macaques in a safari-style zoo. Journal of Parasitology. 2005;91(3):716-719.

  5. Horiuchi A, Satou T, Akao N, Koike K, Fujita K, Nikaido T. The effect of free and polyethylene glycol-liposome-entrapped albendazole on larval mobility and number in Toxocara canis infected mice. Vet Parasitol. 2005;129:83-87.

  6. Akao N. Critical assessment of existing and novel model systems of toxocariasis. In: Holland C, Smith H, editors. Toxocara: The Enigmatic Parasite. Oxfordshire: CABI Publishing; 2005. p. 74-85.

  7. Akao N. Human dirofilariasis in Japan. In: Kimura E, Rim, H.-J., Dejian, S. & Weerasooriya, M.V., editor. Filariasis in Asia and Western Pacific Islands. Tokyo: AAA Committee, The Federaation of Asian Parasitologists; 2005. p. 145-152.

  8. Ayi Irene, Nobuaki Akao, Kwabena Mante Bosompemb, Stephen K. Akafoc, James Clarked, Lydia Nyadore, Kwesi A. Apea-Kubif, and Koichiro Fujita. 2005. Development of membrane-based tests for the detection of urinary antigens and antibodies in human toxoplasmosis: preliminary studies in Ghanaian patients. Acta Tropica, 2005; 93:151-159.

  1. Ohnishi K, Kogure H, Kaneko S, Kato Y, Akao N. Strongyloidiasis in a patient with acuired immunodeficiency syndrome. J. Infect. Chemother. 2004;10:178-180.

  2. Sato H, Matsuo K, Osanai A, Kamiya H, Akao N, Owaki S, Furuoka H. Larval migrans by Baylisascaris trasfuga: Fatal neurological disease in Monglian jirds, but not in mice. Journal of Parasitology 2004;90(4):774-781.

  1. Akao N, Hayashi E, Sato H, Fujita K, Furuoka H. Diffuse retinochoroiditis due to Baylisascaris procyonis in Monglian gerbils. Journal of Parasitology 2003;89(1):174-175.

  2. Akao N, Tomoda M, Hayashi E, Takayanagi TH, Fujita K. Cerebellar ataxia due to Toxocara infection in Mongolian gerbils. Veterinary Parasitology 2003;113:229-237.

  3. Hayashi E, Akao N, Fujita K. Evidence for optic nerve involvement as a migratory route of larvae in ocular toxocariasis in Mongolian gerbils. Journal of Helminthology 2003; 77(4): 311-315.