1. Toshihiko Aki, Takeshi Funakoshi, Kana Unuma, Koichi Uemura
    Inverse regulation of GSDMD and GSDME gene expression during LPS-induced pyroptosis in RAW264.7 macrophage cells
    Apoptosis . 2022 Feb;27(1-2):14-21.
    doi: 10.1007/s10495-022-01708-1.

  1. Toshihiko Aki, Kana Unuma, and Koichi Uemura
    The Role of Peroxiredoxins in the Regulation of Sepsis
    Antioxidants (Basel) . 2022 Jan 6;11(1):126.
    doi: 10.3390/antiox11010126.

  1. Wen S, Unuma K, Makino Y, Mori H, Uemura K.
    Fatal consequence after MiraDry® treatment: Necrotizing fasciitis complicated with streptococcal toxic shock syndrome.
    Leg Med (Tokyo). 2022 May 30;58:102095.
    doi: 10.1016/j.legalmed.2022.102095.

  1. Wen S, Aki T, Funakoshi T, Unuma K, Uemura K.
    Role of Mitochondrial Dynamics in Cocaine’s Neurotoxicity.
    Int J Mol Sci . 2022 May 12;23(10):5418.
    doi: 10.3390/ijms23105418.

  1. Wen S, Unuma K, Uemura K.
    Two fatal cases due to inadvertent discharge of carbon dioxide fire suppressant: Intoxication or asphyxiation?
    J Forensic Leg Med. 2022 Jun 7;90:102390.
    doi: 10.1016/j.jflm.2022.102390.


  1. Norii T, Makino Y, Unuma K, Hatch GM, Adolphi NL, Dallo S, Albright D, Sklar DP, Braude D.
    Extraglottic Airway Device Misplacement: A Novel Classification System and Findings in Postmortem Computed Tomography.
    Ann Emerg Med. 2021 Jan 15:S0196-0644(20)31266-X.
    doi: 10.1016/j.annemergmed.2020.10.005.

  1. Norii T, Makino Y, Unuma K, Adolphi NL, Albright D, Sklar DP, Crandall C, Braude D.
    CT imaging of extraglottic airway device-pictorial review.
    Emerg Radiol. 2021 Feb 2.
    doi: 10.1007/s10140-021-01909-2.

  1. Wen S, Unuma K, Chinuki Y, Hikino H, Uemura K.
    Fatal anaphylaxis due to alpha-gal syndrome after initial cetuximab administration: The first forensic case report.
    Leg Med (Tokyo). 2021 Apr 7;51:101878.
    doi: 10.1016/j.legalmed.2021.101878.

  1. Wen S, Unuma K, Watanabe R, Uemura K.
    Diagnosis by forensic autopsy of cannula malposition resulting in fatal tension pneumothorax after attempted percutaneous tracheostomy: A short communication.
    J Forensic Leg Med. 2021 May 6;81:102177.
    doi: 10.1016/j.jflm.2021.102177

  1. Tatsuhiko Murata, Kanako Noritake, Toshihiko Aki, Koichi Uemura.
    Possible roles of AMPK and macropinocytosis in the defense responses against Δ9-THC toxicity on HL-1 cardiomyocytes
    Toxicol Rep. 2021 Apr 30;8:980-987.
    doi: 10.1016/j.toxrep.2021.04.014.

  1. Moeka Nomura, Kana Unuma, Toshihiko Aki, Koichi Uemura.
    Sustained splenic contraction after daily cocaine administration in rats
    PLoS One . 2021 Jun 4;16(6):e0252853.
    doi: 10.1371/journal.pone.0252853.

  1. Yamada A, Unuma K, Arai N, Kitamura O, Uemura K.
    Inappropriate diet and fatal malnutrition in a 10-year-old child fed only infant formula throughout life: Novel pathological diagnostic criterion for starvation via lipophagy.
    Forensic Sci Int. 2021 Jul 4;325:110896.
    doi: 10.1016/j.forsciint.2021.110896.

  1. Unuma K, Makino Y, Yamamoto K, Hattori S, Arai N, Sakai K, Kitagawa M, Uemura K, Kanegane H.
    Fatal intracranial hemorrhage due to infantile acute lymphoblastic leukemia mimicking abusive head trauma.
    J Forensic Sci. 2021 Jul 23.
    doi: 10.1111/1556-4029.14815.

  1. Ota M, Funakoshi T, Aki T, Unuma K, Uemura K.
    Oxcarbazepine induces mitotic catastrophe and apoptosis in NRK-52E proximal tubular cells.
    Toxicol Lett . 2021 Oct 10;350:240-248.
    doi: 10.1016/j.toxlet.2021.07.018.

  1. 秋利彦, 上村公一
    月刊「細胞」 53, 33-35
  1. Aki T, Uemura K
    Cell Death and Survival Pathways Involving ATM Protein Kinase
    Genes (Basel) . 2021 Oct 7;12(10):1581.
    doi: 10.3390/genes12101581.

  1. Wen S, Unuma K, Watanabe R, Makino Y, Uemura K.
    Forensic evaluation of fatal-suffocating retropharyngeal haematoma secondary to cervical fractures: Report of two cases.
    J Forensic Leg Med. 2021 Nov 15;85:102274.
    doi: 10.1016/j.jflm.2021.102274.

  1. Wen S, Unuma K, Funakoshi T, Aki T, Uemura K.
    Altered cardiac mitochondrial dynamics and biogenesis in rat after short-term cocaine administration.
    Sci Rep . 2021 Dec 16;11(1):24129.
    doi: 10.1038/s41598-021-03631-y.

  1. 上村公一.
    犯罪学雑誌 87; 16-19, 2021.


  1. Toshihiko Aki, Takeshi Funakoshi, Kanako Noritake, Kana Unuma, Koichi Uemura
    Extracellular Glucose Is Crucially Involved in the Fate Decision of LPS-stimulated RAW264.7 Murine Macrophage Cells
    Sci Rep . 2020 Jun 29;10(1):10581.
    doi: 10.1038/s41598-020-67396-6

  1. Tetsushi Kitayama , Takashi Fukagawa , Haruhiko Watahiki, Yusuke Mita , Koji Fujii , Kana Unuma , Koichi Sakurada , Koichi Uemura , Kazumasa Sekiguchi , Natsuko Mizuno
    Evaluation of Rapid DNA system for buccal swab and disaster victim identification samples
    Leg Med (Tokyo) 2020 Sep;46:101713.
    doi: 10.1016/j.legalmed.2020.101713.

  1. Unuma K, Watanabe R, Hirayama N, Uemura K.
    Autopsy Identification of Viable Mycobacterium Tuberculosis in the Lungs of a Markedly Decomposed Body.
    J Forensic Sci. 2020 Aug 31.
    doi: 10.1111/1556-4029.14532.

  1. Kanako Noritake, Toshihiko Aki, Shintaro Isa, Koichi Uemura
    Pyroptotic cell death by exposure to 1-butanol in H9c2 cardiomyoblastoma cells
    Heliyon 6 (2020) e05503
    doi: 10.1016/j.heliyon.2020.e05503

  1. Shuheng Wen, Toshihiko Aki, Kana Unuma and Koichi Uemura
    Chemically Induced Models of Parkinson’s Disease: History and Perspectives for the Involvement of Ferroptosis
    Front. Cell. Neurosci. (2020) 14: 581191
    doi: 10.3389/fncel.2020.581191

  1. Kunihiro J, Nabeka H, Wakisaka H, Unuma K, Khan MSI, Shimokawa T, Islam F, Doihara T, Yamamiya K, Saito S, Hamada F, Matsuda S.
    Prosaposin and its receptors GRP37 and GPR37L1 show increased immunoreactivity in the facial nucleus following facial nerve transection.
    PLoS One. 2020 Dec 1;15(12):e0241315.
    doi: 10.1371/journal.pone.0241315. eCollection 2020.

  1. Nagai M, Sakurada K, Imaizumi K, Ogawa Y, Uo M, Funakoshi T, Uemura K.
    Evaluation of Parameters for Estimating the Postmortem Interval of Skeletal Remains Using Bovine Femurs: A Pilot Study.
    Diagnostics (Basel). 2020 Dec 9;10(12):1066.
    doi: 10.3390/diagnostics10121066.


  1. Kana Unuma, Toshihiko Aki, Ayaka Yamashita, Ayaka Yoshikawa, Koichi Uemura
    Hydrogen sulfide donor NaHS causes bronchitis with enhanced respiratory secretion in rats
    The Journal of Toxicological Sciences2019;44(2):107-112.
    doi: 10.2131/jts.44.107

  1. Aki T, Unuma K, Noritake K, Hirayama N, Funakoshi T, Uemura K.
    Formation of high molecular weight p62 by CORM-3.
    PLoS One. 2019 Jan 8;14(1):e0210474.
    doi: 10.1371/journal.pone.0210474.
  1. Unuma K, Makino Y, Sasaki Y, Iwase H, Uemura K.
    Presepsin: A potential superior diagnostic biomarker for the postmortem differentiation of sepsis based on the Sepsis-3 criteria.
    Forensic Sci Int. 2019 Jun;299:17-20.
    doi: 10.1016/j.forsciint.2019.03.034.
  1. Kana Unuma, Ayaka Yoshikawa, Toshihiko Aki, Koichi Uemura.
    Increased circulating Prx4 in sepsis model rats involves secretion from hepatocytes and is mitigated by GYY4137
    Journal of Toxicologic Pathology. 2019 Oct;32(4):305-310.
    doi: 10.1293/tox.2019-0030.
  1. Funakoshi T, Furukawa M, Aki T, Uemura K.
    Repeated exposure of cocaine alters mitochondrial dynamics in mouse neuroblastoma Neuro2a.
    Neurotoxicology. 2019 Dec;75:70-77.
    doi: 10.1016/j.neuro.2019.09.001.


  1. Toshihiko Aki, Kanako Noritake, Takeshi Funakoshi, Koichi Uemura.
    Modes of Chemically Induced Cell Death.
    Comprehensive Toxicology 3rd ed Volume 1 (General subjects),
    (2018) 229-253, Elsevier UK
  1. Unuma K, Aki T, Nagano S, Watanabe R, Uemura K.
    The down-regulation of cardiac contractile proteins underlies myocardial depression during sepsis and is mitigated by carbon monoxide.
    Biochem Biophys Res Commun. 2018; 495: 1668-1674
  1. Hirayama N, Aki T, Funakoshi T, Noritake K, Unuma K, Uemura K.
    Necrosis in human neuronal cells exposed to paraquat.
    J. Toxicol. Sci. 2018;43(3):193-202.
  1. Toshihiko Aki, Kana Unuma, Kanako Noritake, Hatsumi Kurahashi, Takeshi Funakoshi, Koichi Uemura.
    Interaction of carbon monoxide-releasing ruthenium carbonyl CORM-3 with plasma fibronectin.
    Toxicology in Vitro. 2018 Mar 23;50:201-209.
  1. Toshihiko Aki, Kanako Noritake, Kana Unuma, Koichi Uemura.
    Autophagic regulation of cardiomyocyte survival and heart regeneration.
    “Autophagy in health and disease”, “Stem Cell Biology and Regenerative Medicine” book series, published by Humana press, Springer-Nature, 2018, pp101-118
    ISBN 978-3-319-98145-1 ISSN 2196-8985

  1. 佐野智美、船越丈司、則竹香菜子、鵜沼香奈、上村公一
    法医学の実際と研究 61:71-77, 2018.


  1. Unuma K, Aki T, Noritake K, Funakoshi T, Uemura K.
    A CO-releasing molecule prevents annexin A2 down-regulation and associated disorders in LPS-administered rat lung.
    Biochem Biophys Res Commun. 2017 Jun 3;487(3):748-754.
    doi: 10.1016/j.bbrc.2017.04.131.
  1. Ryo Watanabe, Kana Unuma, Kanako Noritake, Takeshi Funakoshi, Toshihiko Aki, Koichi Uemura.
    Ataxia telangiectasia and rad3 related (ATR)-promyelocytic leukemia protein (PML) pathway of the DNA damage response in the brain of rats administered arsenic trioxide.
    J. Toxicologic Pathology. 2017; 30: 333-337.
  1. Noritake K, Aki T, Kimura M, Funakoshi T, Unuma K, Uemura K.
    Restoration of YAP activation rescues HL-1 cardiomyocytes from apoptotic death by ethanol.
    J Toxicol Sci. 2017;42(5):545-551.
  1. Toshihiko Aki, Kana Unuma, and Koichi Uemura.
    Emerging roles of mitochondria and autophagy in liver injury during sepsis.
    Cell Stress. Vol.1, No.2:79-89.


  1. Kimura-Kojima H, Unuma K, Funakoshi T, Kato C, Komatsu A, Aki T, Uemura K.
    Increased MFG-E8 expression and its implications in the vascular pathophysiology of cocaine abuse.
    J Toxicol Pathol. 2016 Apr;29(2):131-8.
    doi: 10.1293/tox.2015-0072.
  1. Watanabe M, Unuma K, Makino Y, Komatsu A, Yamada A, Nagai H, Uemura K.
    An Autopsy Case of Asphyxia Caused by Uncontrolled Hemorrhage Following Transbronchial Lung Biopsy
    J Clin Respir Dis Care 2: 117(2016).
    doi: 10.4172/2472-1247.1000117
  1. 鵜沼 香奈、秋 利彦.
    月刊「細胞」 48(11): 31-34 (2016)
  1. Fujii Y, Funakoshi T, Unuma K, Noritake K, Aki T, Uemura K.
    Hydrogen sulfide donor NaHS induces death of alveolar epithelial L2 cells that is associated with cellular shrinkage, transgelin expression and myosin phosphorylation.
    J Toxicol Sci. 2016;41(5):645-54.
    doi: 10.2131/jts.41.645.
  1. Funakoshi T, Aki T, Tajiri M, Unuma K, Uemura K.
    Necroptosis-like Neuronal Cell Death Caused by Cellular Cholesterol Accumulation.
    J Biol Chem. 2016 Nov 25;291(48):25050-25065.


  1. Watanabe M, Unuma K, Fujii Y, Noritake K, Uemura K.
    An autopsy case of vagus nerve stimulation following acupuncture
    Legal Medicine (Tokyo). 2015 Mar;17(2): 120-122
    doi:10.1016/j.legalmed.2014.11.001. Epub 2014 Nov 11.
  1. Okawa S, Unuma K, Yamada A, Aki T, Uemura K.
    Lipopolysaccharide induces expression of collagen VI in the rat lung
    Journal of Toxicologic Pathology. 2015 Jan;28(1):37-41.
    doi: 10.1293/tox.2014-0053. Epub 2014 Dec 27.
  1. Yamada A, Aki T, Unuma K, Funakoshi T, Uemura K.
    Paraquat induces epithelial-mesenchymal transition-like cellular response resulting in fibrogenesis and the prevention of apoptosis in human pulmonary epithelial cells.
    PLos One. 2015 Mar 23;10(3):e0120192.
    doi: 10.1371/journal.pone.0120192. eCollection 2015.
  1. Aki T, Funakoshi T, Uemura K.
    Regulated necrosis and its implications in toxicology.
    Toxicology. 2015 Apr 9;333:118-126.
    doi: 10.1016/j.tox.2015.04.003.
  1. Watanabe M, Unuma K, Makino Y, Noritake K, Yamada A, Iwase H, Uemura K.
    An Autopsy Case of Acute Massive Hematochezia Caused by Superior Mesenteric Vein Thrombosis: A First Report in Forensic Medicine.
    J Forensic Sci. 2015 Aug 13.
    doi: 10.1111/1556-4029.12903. [Epub ahead of print]
  1. Nagai H, Kuwahira I, Schwenke DO, Tsuchimochi H, Nara A, Ogura S, Sonobe T, Inagaki T, Fujii Y, Yamaguchi R, Wingenfeld L, Umetani K, Shimosawa T, Yoshida K, Uemura K, Pearson JT, Shirai M.
    Pulmonary Macrophages Attenuate Hypoxic Pulmonary Vasoconstriction via β3AR/iNOS Pathway in Rats Exposed to Chronic Intermittent Hypoxia.
    PLoS One. 2015 Jul 1;10(7):e0131923.
    doi: 10.1371/journal.pone.0131923. eCollection 2015.
  1. Noritake K, Aki T, Funakoshi T, Unuma K, Uemura K.
    Direct Exposure to Ethanol Disrupts Junctional Cell-Cell Contact and Hippo-YAP Signaling in HL-1 Murine Atrial Cardiomyocytes.
    PLoS One. 2015 Aug 28;10(8):e0136952.
    doi: 10.1371/journal.pone.0136952. eCollection 2015.
  1. Unuma K, Aki T, Funakoshi T, Hashimoto K, Uemura K.
    Extrusion of mitochondrial contents from lipopolysaccharide-stimulated cells: Involvement of autophagy.
    Autophagy. 2015 Sep 2;11(9):1520-36.
    doi: 10.1080/15548627.2015.1063765.
  1. Uchida K, Unuma K, Uemura K.
    A fatality in a child with severe fatty liver due to n-butane and isopentane poisoning resulting from long-term inhalation of an antiperspirant aerosol.
    Forensic Sci Med Pathol. 2015 Dec;11(4):631-2.
    doi: 10.1007/s12024-015-9712-6.
  1. Kuroda R, Shintani-Ishida K, Unuma K, Yoshida K.
    Immobilization Stress With α2-Adrenergic Stimulation Induces Regional and Transient Reduction of Cardiac Contraction Through Gi Coupling in Rats.
    Int Heart J. 2015 Sep 29;56(5):537-43.
  1. Utsuno H, Kageyama T, Uchida K, Kibayashi K, Sakurada K, Uemura K.
    Pilot study to establish a nasal tip prediction method from unknown human skeletal remains for facial reconstruction and skull photo superimposition as applied to a Japanese male populations.
    J Forensic Leg Med. 2015 Dec 12;38:75-80.
    doi: 10.1016/j.jflm.2015.11.017.
  1. 則竹 香菜子、秋 利彦、上村 公一.
    月刊「細胞」 47(14): 44-47


  1. Yamada A, Unuma K, Kojima H, Uemura K.
    Subarachnoid hemorrhage caused by a traffic accident: De novo aneurysm ruptured 30 years after surgical neck clipping
    Journal of Forensic and Legal Medicine. 2014;22:90-92
  1. Watanabe M, Funakoshi T, Unuma K, Aki T, Uemura K.
    Activation of the ubiquitin-proteasome system against arsenic trioxide cardiotoxicity involves ubiquitin ligase Parkin for mitochondrial homeostasis
    Toxicology. 2014; 322(1) , 43-50. doi: 10.1016/j.tox.2014.04.008
  1. Uchida K, Unuma K, Funakoshi T, Aki T, Uemura K.
    Activation of master autophagy regulator TFEB during systemic LPS administration in cornea
    J Toxicol Pathol. 2014; 27(2):153-8. doi:/10.1293/tox.2014-0004
  1. Nagai H, Kuwahira I, Schwenke DO, Tsuchimochi H, Nara A, Inagaki T, Ogura S, Fujii Y, Umetani K, Shimosawa T, Yoshida K, Pearson JT, Uemura K, Shirai M.
    β2-Adrenergic receptor-dependent attenuation of hypoxic pulmonary vasoconstriction prevents progression of pulmonary arterial hypertension in intermittent hypoxic rats.
    PLoS One. 2014 Oct 28;9(10):e110693. doi: 10.1371/journal.pone.0110693. eCollection 2014.


  1. Unuma K, Aki T, Matsuda S, Funakoshi T, Yoshida K, Uemura K.
    Inducer of heme oxygenase-1 cobalt protoporphyrin accelerates autophagy and suppresses oxidative damages during lipopolysaccharide treatment in rat liver.
    Hepatol Res. 2013 Jan;43(1):91-6. doi: 10.1111/j.1872-034X.2012.01049.x.
  1. Funakoshi T, Aki T, Unuma K, Uemura K.
    Lysosome vacuolation disrupts the completion of autophagy during norephedrine exposure in SH-SY5Y human neuroblastoma cells.
    Brain Res. 2013 Jan 15;1490:9-22. doi: 10.1016/j.brainres.2012.10.056.
  1. Hirose I, Harada K, Kuroda R, Ishii Y, Nakajima M, Kamei Y, Takazawa Y, Yoshida KI.
    An autopsy report on a ruptured rudimentary horn (uterine anomaly) with ectopic pregnancy.
    Forensic Sci Int. 2013 Jan 10;224(1-3):e4-6. doi: 10.1016/j.forsciint.2012.10.019.
  1. Unuma K, Aki T, Funakoshi T, Yoshida K, Uemura K.
    Cobalt Protoporphyrin Accelerates TFEB Activation and Lysosome Reformation during LPS-Induced Septic Insults in the Rat Heart.
    PLoS One. 2013;8(2):e56526. doi: 10.1371/journal.pone.0056526.
  1. Sugihara M, Odagiri F, Suzuki T, Murayama T, Nakazato Y, Unuma K, Yoshida K, Daida H, Sakurai T, Morimoto S, Kurebayashi N.
    .Usefulness of running wheel for detection of congestive heart failure in dilated cardiomyopathy mouse model.
    PLoS One. 2013;8(1):e55514. doi: 10.1371/journal.pone.0055514.
  1. Unuma K, Harada K, Oka T, Uemura K.
    Starch accumulation in the lungs of two infants following positive ventilation.
    Forensic Sci Med Pathol. 2013. 9(4), 554-557.
  1. Fujii Y, Funakoshi T, Uchida K, Watanabe M, Saka K, Uemura K.
    An autopsy case of acute carbon monoxide poisoning with fatal hypnotic drugs in the blood.
    Int Med J. 2013;20(5):587-588.
  1. Bessho M, Aki T, Funakoshi T, Unuma K, Noritake K, Kato C, Uemura K.
    Rho-Kinase Inhibitor Y-27632 Attenuates Arsenic Trioxide Toxicity in H9c2 Cardiomyoblastoma Cells.
    Cardiovasc Toxicol. 2013; 13(3) , 267-277.
  1. Aki T, Funakoshi T, Unuma K, Uemura K.
    Impairment of autophagy: From hereditary disorder to drug intoxication.
    Toxicology. 2013;311(3):205-215. doi:10.1016/j.bbr.2011.03.031.
  1. Funakoshi-Hirose I, Aki T, Unuma K, Funakoshi T, Noritake K, Uemura K.
    Distinct effects of methamphetamine on autophagy-lysosome and ubiquitin-proteasome systems in HL-1 cultured mouse atrial cardiomyocytes.
    Toxicology. 2013;312(4):74-82. doi:10.1016/j.tox.2013.07.016.
  1. Kashima J, Shintani-Ishida K, Nakajima M, Maeda H, Unuma K, Uchiyama Y, Yoshida KI.
    Immunohistochemical study of the autophagy marker microtubule-associated protein 1 light chain 3 in normal and steatotic human livers.
    Hepatol Res. 2013 Jun 17. doi: 10.1111/hepr.12183.


  1. Aki T, Nara A, Uemura K.
    Cytoplasmic vacuolization during exposure to drugs and other substances.
    Cell Biol Toxicol. 2012;28(3):125-131.
  1. Unuma K, Uozaki H, Kuroda R, Uemura K, Yoshida K.
    Death from axillary haemorrhage during haemodialysis in a patient with a histoly of microscopic polyangiitis.
    BMJ Case Rep 2012;doi:10.1136/bcr.11.2011.5194
  1. Bessho M, Unuma K, Nara A, Uemura K.
    A case in which a bone fragment caused by a bullet made a second channel in addition to the bullet channel.
    Leg Med (Tokyo). 2012 July; 14(4):188-190.
  1. Noritake K, Aki T, Funakoshi T, Unuma K, Nara A, Kato C, Uemura K.
    Critical roles of Rho-associated kinase in membrane blebbing and mitochondrial pathway of apoptosis caused by 1-butanol.
    Toxicol in vitro. 2012; 26(6):849-855.
  1. Nara A, Aki T, Funakoshi T, Unuma K, Uemura K.
    Hyperstimulation of macropinocytosis leads to lysosomal dysfunction and cell death during exposure to methamphetamine in differentiated SH-SY5Y cells.
    Brain Res. 2012; 1466:1-14.
  1. Unuma K, Aki T, Matsuda S, Funakoshi T, Yoshida K, Uemura K.
    Elimination and active extrusion of liver mitochondrial proteins during LPS administration in rat.
    Hepatology Res. 2013;43(5):526-534. doi:10.1111/j.1872-034X.2012.01084.x.


  1. Noritake K, Unuma K, Nara A, Uchida K, Shiratori T, Watanuki Y, Funakoshi T, Uemura K.
    Autopsy findings of a patient with rapidly progressive massive ascites caused by alcoholic cirrhosis.
    Leg Med (Tokyo). 2011 May;13(3):148-50.
  1. Funakoshi T, Aki T, Nakayama H, Watanuki Y, Imori S, Uemura K.
    Reactive oxygen species-independent rapid initiation of mitochondrial apoptotic pathway by chelerythrine.
    Toxicol In Vitro. 2011 Dec;25(8): 1581-7
  1. Unuma K, Harada K, Furutani M, Furutani Y, Nakajima M, Nakanishi T, Matsuoka R, Yoshida KI.
    Multiple stenotic arteriopathy in a 72-year-old female with Williams syndrome.
    J Clin Pathol 2011; 64(4): 368-370.
  1. Unuma K, Harada K, Funakoshi T, Uemura K.
    Sudden death of an alcoholic elderly man with acute esophageal necrosis (black esophagus).
    Forensic Sci Int. 2011 Oct 10;212(1-3):e15-7.
  1. Kuroda R, Harada K, Kobayashi T, Nagai H, Unuma K, Saka K, Shintani-Ishida K, Yoshida K.
    Sudden cardiac death caused by the administration of a β(2)-agonist for asthma attack.
    Int J Cardiol. 2011 Dec 15;153(3):e56-8.


  1. Nara A, Aki T, Funakoshi T, Uemura K.
    Methamphetamine induces macropinocytosis in differentiated SH-SY5Y human neuroblastoma cells.
    Brain Res. 2010 Sep 17;1352:1-10.
  2. Aki T, Nara A, Funakoshi T, Uemura K.
    Bifurcate effects of glucose on caspase-independent cell death during hypoxia.
    Biochem Biophys Res Commun 396; 614-618: 2010
  3. Mihoko Kondo-Nakamura, Kaori Shintani-Ishida, Koichi Uemura, Ken-ichi Yoshida.
    Brief exposure to carbon monoxide preconditions cardiomyogenic cells against apoptosis in ischemia reperfusion.
    Biochem Biophys Res Commun 393; 449-454: 2010
  4. Akina Nara, Toshihiko Aki, Takeshi Funakoshi, Kyoko Uchida, Haruka Nakayama, Koichi Uemura.
    Death due to blood transfusion-induced anaphylactic shock: A case report.
    Legal Med 12; 148-150: 2010.
  5. Unuma K, Shintani-Ishida K, Yahagi N, Tsushima K, Shimosawa T, Ueyama T, Yoshida K.
    Restraint stress induces connexin-43 translocation via α-adrenoceptors in rat heart.
    Circ J 2010; 74(12): 2693-2701.
  6. Unuma K, Shintani-Ishida K, Tsushima K, Shimosawa T, Ueyama T, Kuwahara M, Yoshida K.
    Connexin-43 redistribution and gap junction activation during forced restraint protects against sudden arrhythmic death in rats.
    Circ J 2010; 74(6): 1087-1095.
  7. Tojo A, Unuma K, Harada K, Yoshida K, Fujita T.
    Localization and mechanism of nephrocalcinosis in pseudo-Bartter's syndrome.
    Kidney Int 2010; 77(9): author reply 831.
  8. Unuma K, Harada K, Nakajima M, Ito T, Okutsu K, Yoshida K.
    Unexpected death of a patient with rheumatoid arthritis complicated by a cervical deformity.
    Leg Med 2010; 12(5): 242-245.
  9. 魚住尚宏、鶴田 潤、上村公一. 
    日本医事新報 4474: 86-88, 2010.
  10. 上村公一. 
    死後の血液検査の妥当性 ---生化学検査を中心として.
    医学のあゆみ. 234(3), 223-226, 2010.


  1. Toshihiko Aki and Shuichi Yanagisawa.
    Application of rice nuclear proteome analysis to the identification of evolutionarily conserved and glucose?responsive nuclear proteins.
    J. Proteome Res. 2009; 8, 3912-3924
  2. 落合恵理子、奈良明奈、上村公一、福井謙二、青柳美輪子、岩楯公晴.
    DNA多型 2009; 17:180-183.
  3. Akina Nara, Shinji Harihara, Kimiharu Iwadate, Koichi Uemura.
    Sequence analysis for HV I region of mitochondrial DNA using WGA (Whole Genome Amplification) method.
    Legal Med 2009; 11: S115-S118.
  4. Koichi Uemura , Kyoko Uchida, Akina Nara and Eriko Ochiai.
    A fatal case of air-bag-mediated liver injury in an unrestrained driver.
    Legal Med 2009; 11: S555-S557.


  1. Saka K, Uemura K, Shintani-Ishida K, Yoshida K.
    Determination of amobarbital and phenobarbital in serum by gas chromatography-mass spectrometry with addition of formic acid to the solvent.
    J Chromatogr B. 2008; 869: 9-15.
  2. Aki T, Funakoshi T, Nishida-Kitayama J, Mizukami Y.
    TPRA40/GPR175 regulates early mouse embryogenesis through functional membrane transport by Sjogren's syndrome-associated protein NA14.
    J Cell Physiol. 217(1):194-206, 2008.
  3. 相馬玲子,奈良明奈,酒井亜美,針原針二,岩楯公晴,青柳美輪子.
    DNA多型. 16: 266-269,2008.
  4. 渡辺喬士,岩楯公晴,水上創,原修一,栗岩ふみ,遠藤任彦,森晋二郎,永井智紀,福永龍繁.
    DNA多型. 16: 194-198, 2008.
  5. 奈良明奈,内田恭子,落合恵理子,吉田謙一,上村公一.
    法医学の実際と研究 51:143-148, 2008
  6. Uemura K, Shintani-Ishida K, Saka K, Nakajima M, Ikegaya H, Kikuchi Y, Yoshida K.
    Biochemical blood markers and sampling sites in forensic autopsy.
    J Forensic Legal Med 15: 312-317, 2008.
  7. Uemura K, Takahashi S, Shintani-Ishida K, Nakajima M, Saka K, Yoshida K.
    A death due to perirenal hematoma complicating extracorporeal shockwave lithotripsy.
    J Forensic Sci. 53: 469-471, 2008.
  8. Uemura K, Ueyama T, Shintani-Ishida K, Unuma K, Yoshida K.
    An autopsy report on four sudden cardiac death cases by immobilization.
    Int Med J 15: 301-305, 2008.


  1. 上村公一、中嶋 信、坂 幹樹、新谷(石田) 香、中村美穂子、大野 博、吉田謙一.
    法医学の実際と研究2007; 50: 119-125.
  2. Shintani-Ishida K, Uemura K, Yoshida K.
    Hemichannels in cardiomyocytes open transiently during ischemia and contribute to reperfusion injury following brief ischemia.
    Am J Physiol Heart Circ Physiol 2007; 293: 1714-1720.
  3. Saka K, Uemura K, Shintani-Ishida K, Yoshida K.
    Acetic acid improves the sensitivity of theophylline analysis by gas chromatography?mass spectrometry.
    J Chromato B 2007; 846( 1-2): 240-244.
  4. Ohno H, Uemura K, Shintani-Ishida K, Nakamura M, Inomata M, Yoshida K.
    Ischemia promotes calpain-mediated degradation of p120-catenin in SH-SY5Y cells.
    Biochem Biophy Res Comm 2007; 353(3): 547-552.
  5. 奈良明奈、針原伸二、青柳美輪子、相馬玲子、岩楯公晴.
    DNA多型 2007; 15: 268-271.


  1. Uemura K, Kikuchi Y, Shintani-Ishida K, Nakajima M, Yoshida K.
    A fatal case of post-operative pulmonary thromboembolism with cosmetic liposuction.
    J Clin Forensic Med 13(1), 41-43 (2006)
  2. Uemura K, Adachi-Akahane S, Shintani-Ishida K, Yoshida K.
    Carbon monoxide protects cardiomyogenic cells against ischemic death through L-type Ca2+ channel inhibition.
    Biochem Biophys Res Commun 334(2), 661-668 (2005)
  3. Uemura K, Fujimiya T, Ohbora Y, Yasuhara M and Yoshida K.
    Individual Differences in the Kinetics of Alcohol Absorption and Elimination: A Human Study.
    Forensic Sci Med Pathol 1, 27-30 (2005)
  4. Ohnishi ST, Ohnishi T, Muranaka S, Fujita H, Kimura H, Uemura K, Yoshida K, Utsumi K.A
    possible site of superoxide generation in the complex I segment of rat heart mitochondria.
    J Bioenerg Biomembr 37(1), 1-15 (2005)
  5. Uemura K, Yoshida K, et al.
    Sudden death of a patient with primary hypereosinophilia, colon tumours, and pulmonary emboli.
    J Clin Pathol 57(5), 541-543 (2004)
  6. Uemura K, Aki T, Yamaguchi K, Yoshida K.
    Protein kinase C-e protects PC12 cells against methamphetamine-induced death : Possible involvement of suppression of glutamate receptor.
    Life Sci 72, 1595-1607 (2003)
  7. Uemura K, Hoshino S, Uchida K, Tsuruta R, Maekawa T, Yoshida K.
    Hypothermia attenuates delayed cortical cell death and ROS generation following CO inhalation.
    Toxicol Lett 145(2), 101-106 (2003)
  8. Uemura K, Sorimachi Y, Yashiki M, Yoshida K.
    Two fatal cases involving concurrent use of methamphetamine and morphine.
    J Forensic Sci 48(5), 1179-1181 (2003)
  9. 上村公一、吉田謙一.
    一酸化炭素中毒 - 基礎から臨床へ -.
    日本医事新報 4154, 23-28 (2003)
  10. Kudo R, Adachi J, Uemura K, Maekawa T, Ueno Y, Yoshida K.
    Lipid peroxidation in the rat brain after CO inhalation is temperature dependent.
    Free Radical Biol Med, 31 (11) , 1417-1423 (2001)
  11. Uemura K, Yoshida K.
    Seat belt induced transection of trachea in a child held on laps of adult upon car diving.
    J Forensic Sci 46(3), 714-716, 2001.
  12. Uemura K, Harada K, Sadamitsu D, Tsuruta R, Takahashi M, Aki T, Yasuhara M, Maekawa T, Yoshida K.
    Apoptotic and necrotic brain lesions in a fatal case of carbon monoxide poisoning.
    Forensic Sci Int 116(2-3), 213-219, 2001.
  13. Uemura K, Harada K, Shiotani A, Kai A, Urata Y, Yasuhara M, Yoshida K.
    Obesity-sleep apnea (Pickwickian) syndrome: autopsy findings and a medicolegal review.
    Legal Medicine 2: 36-41, 2000.
  14. Uemura K, Li Y-J, Ohbora Y, Fujimiya T, Komura S.
    Effects of repeated cocaine administration on alcohol consumption.
    J Stud Alc 59(1), 115-118, 1998.
  15. Uemura K, Komura S.
    Death caused by triazolam and ethanol intoxication.
    Am J Foren Med Path 16(1), 66-68,1995.
  16. Imagawa T, Uemura K, Nagai Z, Kawanisi M.
    Synthesis of 2-(1-hydroxyalkyl) acryronitriles by the cocatalysis of a base and an acid.
    Synth Commun 14(13), 1267-1273, 1984.