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2008”N


  1. Jin S-H, Akiyama Y, Fukamachi H, Yanagihara K, Akashi T, Yuasa Y:IQGAP2 inactivation through aberrant promoter methylation and promotion of invasion in gastric cancer cells. Int. J. Cancer, 2008:122:1040-1046.
  2. Yuasa Y: Frontiers in epigenetics medicine: foreword: Miniseries collected from a symposium organized by the Study Group on Epigenetics Medicine held at the 77th Annual Meeting of the Japanese Society for Hygiene.
    Environ. Health Prev. Med., 2008:13:2.
  3. Otsubo T, Akiyama Y, Yanagihara K, Yuasa Y: SOX2 is frequently down-regulated in gastric cancers and inhibits cell growth through cell cycle arrest and apoptosis. Brit. J. Cancer 2008:98:824-831.
  4. Fukamachi H, Mimata A, Tanaka I, Ito K, Ito Y, Yuasa, Y: Differentiation in vitro of Runx3-/-p53-/- gastric epithelial cells into intestinal type cells. Cancer Sci. 2008:99:671-676.
  5. Wanajo A , Sasaki A , Nagasaki H, Shimada S, Otsubo T, Owaki S, Shimizu Y, Eishi Y, Kojima K, Nakajima Y, Kawano T, Yuasa Y, Akiyama Y: Methylation of the calcium channel-related gene, CACNA2D3, is frequent and a poor prognostic factor in gastric cancer. Gastroenterology, in press.
  6. Taguchi, E., Nakamura K, Miura T, Shibuya M, Isoe T. Anti-tumor activity and tumor vessel normalization by the vascular endothelial growth factor receptor tyrosine kinase inhibitor KRN951 in a rat peritoneal disseminated tumor model. Cancer Sci. 99, 623-630, 2008.
  7. Murakami, M. Zheng Y, Hirashima M, Suda T, Morita Y, Ooehara J, Ema H, Fong GH, Shibuya M. VEGFR1 Tyrosine Kinase Signaling Promotes Lymphangiogenesis as Well as Angiogenesis Indirectly via Macrophage Recruitment. Arterioscler Thromb Vasc Biol. 28, 658-664, 2008.
  8. Tsuchida R, Das B, Yeger H, Koren G, Shibuya M, Thorner PS, Baruchel S, Malkin D. Cisplatin treatment increases survival and expansion of a highly tumorigenic side-population fraction by upregulating VEGF/Flt1 autocrine signaling. Oncogene. 2008 Mar 10; [Epub ahead of print]
  9. Endo Y, Sugiyama A, Li SA, Ohmori K, Ohata H, Yoshida Y, Shibuya M, Takei K, Enari M, Taya Y. Regulation of clathrin-mediated endocytosis by p53. Genes Cells. 13, 375-386, 2008.
  10. Fukuhara S, Sako K, Minami T, Noda K, Kim HZ, Kodama T, Shibuya M, Takakura N, Koh GY, Mochizuki N. Differential function of Tie2 at cell-cell contacts and cell-substratum contacts regulated by angiopoietin-1. Nature Cell Biol. 10, 513-526, 2008.
  11. Tammela, T., Zarkada, G., Wallgard, E., Murtomaki, A., Suchting, S., Wirzenius, M., Waltari, M., Hellstrom, M., Schomber, T., Peltonen, R., Freitas, C., Duarte, A., Isoniemi, H., Laakkonen, P., Christofori, G., Yla-Herttuala, S., Shibuya, M., Pytowski, B., Eichmann, A., Betsholtz, C., Alitalo, K. Blocking VEGFR-3 suppresses angiogenic sprouting and vascular network formation. Nature, in press, 2008.
  12. Kerber, M., Reiss, Y., Wickersheim, A., Jugold, M., Kiesslingm, F., Heil, M., Tchaikovski, V., Waltenberger, J., Shibuya, M., Plate, K.H., and Machein, M.R. Flt-1 signaling in macrophages promotes glioma growth in vivo. Cancer Res. in press, 2008.
  13. Kami J, Muranaka K, Yanagi Y, Obata R, Tamaki Y, Shibuya M. Inhibition of choroidal neovascularization by blocking vascular endothelial growth factor receptor tyrosine kinase. Jpn J Ophthalmol. 52, 91-98, 2008.
  14. Nishi JI, Minamino T, Miyauchi H, Nojima A, Tateno K, Okada S, Orimo M, Moriya J, Fong GH, Sunagawa K, Shibuya M, Komuro I. Vascular Endothelial Growth Factor Receptor-1 Regulates Postnatal Angiogenesis Through Inhibition of the Excessive Activation of Akt. Circ Res. 2008 Jun 26. [Epub ahead of print]