分子腫瘍医学業績

2006年


  1. Wen X-Z, Akiyama Y, Baylin SB, Yuasa Y: Frequent epigenetic silencing of the bone morphogenetic protein 2 gene by methylation in gastric carcinomas. Oncogene 2006:25:2666-2673.
  2. Wakana K, Akiyama Y, Aso T, Yuasa Y: Involvement of GATA-4/-5 transcription factors in ovarian carcinogenesis.
    Cancer Letters 2006:241:281-288.
  3. Sekine A, Akiyama Y, Yanagihara K, Yuasa Y: Hath1 up-regulates gastric mucin gene expression in gastric cells.
    Biochem. Biophys. Res. Commun. 2006:344:1166-1171.
  4. Jinawath A, Akiyama Y, Yuasa Y, Pairojkul C: Expression of phosphorylated ERK1/2 and homeodomain protein CDX2 in cholangiocarcinoma. J. Cancer Res. Clin. Oncol. 2006:132:805-810.
  5. Tsuruzoe S, Ishihara K, Uchimura Y, Watanabe S, Sekita Y, Aoto T, Saitoh H, Yuasa Y, Niwa H, Kawasuji M, Baba H, Nakao M: Inhibition of DNA binding of Sox2 by the SUMO conjugation. Biochem. Biophys. Res. Commun. 2006:351:920-926.
  6. Guo M, House MG, Akiyama Y, Qi Y, Capagna DC, Harmon J, Baylin SB, Brock MV, Herman JG: Hypermethylation of the GATA gene family in esophageal cancer. Int. J. Cancer 2006:119:2078-2083.
  7. Takano-Maruyama M, Hase K, Fukamachi H, Kato Y, Koseki H, Ohno H: Foxl1-deficient mice exhibit aberrant epithelial cell positioning due to dysregulated EphB/EphrinB expression in the small intestine. Amer J Physiol Gastrointest Liver Physiol 2006:291:G163-G170.
  8. Yano T, Ito K, Fukamachi H, Chi X-Z, Wee H-J, Inoue K, Ida H, Bouillet P, Strasser A, Bae S-C, Ito Y: The RUNX3 tumor suppressor upregulates Bim in gastric epithelial cells undergoing transforming growth factor ｧ-induced apoptosis. Mol Cell Biol 2006:26:4474-4488.


    [著書]

  1. 湯浅保仁：DNAメチル化と発がんーエピジェネティック疫学 がん研究のいま④がんの疫学. 田島和雄, 古野純典編, 東京大学出版, 2006:134-143.
  2. Fukamachi H (2006) Gastric cancer, intestinal metaplasia and Runx3. In: Recent Advances in Gastrointestinal
    Carcinogenesis (eds. H. Bamba and S. Ota), pp63-85, Transworld Res. Network, Kerala, India.


    [総説]

  1. 湯浅保仁：胆嚢癌の発症機構と遺伝子変化. 肝胆膵 2006:53:257-262.
  2. Fukamachi H: Runx3 controls growth and differentiation of gastric epithelial cells in mammals. Develop Growth Differ 2006: 48: 1-13.