SRPBS (Strategic Research Program for Brain Science) Field E “Understanding molecular and environmental bases for brain health”

SRPBS (Strategic Research Program for Brain Science) Field E “Understanding molecular and environmental bases for brain health”

Elucidation of molecular bases, environmental factors and their organization in the brain, enabling lifelong mental and physical health

Field leader: Hidehiro Mizusawa, MD, PhD, Department of Neurology and Neurological Science Graduate School of Medical and Dental Science Tokyo Medical and Dental University
There is growing expectation from society for brain science to overcome the various problems that our modern aging, diversifying, and complicated society faces. Therefore, the Ministry of Education, Culture, Sports, Science and Technology, Japan decided to promote the Strategic Research Program for Brain Science (SRPBS) for the benefit of society. Field E works on molecular bases and environmental factors to enable the brain to maintain lifelong mental and physical health.
 In order to make this magnificent project succeed, 3 research groups were formed . The healthy development group investigates the organization of the cerebral cortex, hippocampus, amygdala, thalamus and hypothalamus, which are related to developmental disorders, by studying phenotypes, molecular pathology and environmental effects on mouse models. The active life group handles depression, sleep disorders, eating disorders and so on in order to elucidate molecular bases for environmental stresses that destroy the homeostasis of the mind and body. The healthy aging group investigates the molecular bases and environmental factors of normal and pathological aging, including dementia and cerebellar ataxia. Overall, and in detail, influences from lifestyle-related diseases to normal and pathological aging of the cerebrum and cerebellum are studied precisely.