Special Coordination Funds for Promoting Science and Technology
International Collaboration for Development of a New Drug Against Avian Influenza (JST)
Principal Investigator: Takamitsu HOSOYA, PhD (Professor, Graduate School of Biomedical Science)
Avian influenza virus is an influenza A virus of H5N1 subtype that occurs mainly in birds, is highly contagious among birds, and can be deadly to them. H5N1 virus does not usually infect people, but infections with these viruses have occurred in humans. More than 100 people died in Vietnam with H5N1 infection,and Vietnam and Indonesia are the most infected areas of H5N1 in the world. A TMDU research group recently identified a protein kinase which is required for RNA virus proliferation, and furthermore found that synthetic chemical inhibitors of the kinase can suppress proliferation of several RNA viruses including the influenza virus. Therefore, we will develop a new anti-virus drug for patients who suffer avian influenza in cooperation of Vietnam and Japanese scientists. Through international cooperation, we will accelerate the drug development, transfer the knowledge and technology required for pharmaceutical industries from Japan to Vietnam, and produce scientists who can develop new drugs with original ideas and technology in Vietnam.