【著書・総説 Books and Reviews】

  1. Crenshaw MA, Takano Y. Mechanisms by which the enamel organ controls calcium entry into developing enamel. J Dent Res. 1982 Dec;Spec No:1574-9.
  2. Bawden JW, Crenshaw MA, Takano Y, Hammarstrom L. Ion transport through the enamel organ--an update. J Dent Res. 1982 Dec;Spec No:1552-4.
  3. 高野吉郎:エナメル質成熟化にみる形態形成の妙、新歯界 488:25, 1992

  4. 高野吉郎:歯牙発生とエナメル質形成.病態生理. 11(11):830-838, 1992.

  5. 加藤幸夫、実年章年、高田 隆、高野吉郎、青葉孝昭:in vitro における細胞外マトリックスの石灰化の誘導.代謝,29(10):966967, 1992.

  6. 前田健康、佐藤 修、高野吉郎:歯根膜感覚受容器と歯の働き、歯界展望別冊「生理的咬合へのアプローチ」 p.29-42, 1992

  7. 前田健康、高野吉郎:治癒の病理〈臨床編〉第1巻 歯内療法:歯髄保存の限界を求めて. 分担執筆(下野正基,飯島国好編)医歯薬出版,1993.

  8. 高野吉郎、江尻定一、小澤英浩:「組織細胞化学の技術・無機物と色素」, 分担執筆(三島 豊、水平敏知、鈴木庸之編)朝倉書店,1994

  9. Takano, Y.: Histochemical aspects of calcium regulation by the enamel forming cells during matrix formation and maturation. Acta Anatomica Nipponica, 69(2):106-122, 1994.

  10. 高野吉郎:歯根端部の解剖,歯科ジャーナル, 39(4):371-379, 1994.

  11. 高野吉郎:エナメル質石灰化とその調節因子.新潟歯学会雑誌,24(2):1-20, 1994.

  12. 高野吉郎:カルシウムの動きを追って、日本歯科評論 618:5-7, 1994

  13. Takano, Y.: Enamel mineralization and the role of ameloblasts in calcium transport. Connect. Tissue Res. 33(1-3):127-137, 1995

  14. 前田健康、高野吉郎:歯根膜の機能と神経分布:治癒の病理<臨床編>第三巻歯の移植・再植(下野正基、飯島国好編)、医歯薬出版 p.107-125, 1995
  15. 前田健康、高野吉郎:神経の再生:治癒の病理<臨床編>第三巻 歯の移植・再植(下野正基、飯島国好編)、医歯薬出版 p.172-181, 1995
  16. 高野吉郎:歯のエナメル質形成過程で発現するリズムと空間パターン.表面科学 17(6): 321-327, 1996.

  17. 高野吉郎:エナメル質成熟化と有機性基質の脱却.口病誌63巻4号 539-549, 1996.

  18. Takano, Y.: Mineral histochemistry of hard tissues with special reference to localization of calcium binding domains. Proceedings of the Xth International Congress of Histochemistry and Cytochemistry, 380-381, 1996.

  19. 高野吉郎:エナメル質、象牙質形成のメカニズム, 歯科医療11(No.2): 5-14, 1997

  20. 高野吉郎 翻訳:人体組織学 原書第2版 (Human Histology Second Edition)
    内山安男、相磯貞和 監訳、南江堂, 1999.

  21. 高野吉郎 翻訳:歯のできかたのしくみ -その分子生物学的展望-、監訳 永井教之J. Hard Tissue Biololy Vol.8 (special issue) , 1999. 

  22. 高野吉郎 監修:Lars Hammarstrom: エナメルマトリックスタンパクによるセメント質形成を伴う歯周組織再生のメカニズム、歯界展望 93(3): 535-551, 1999.

  23. 高野吉郎 監修:Lars Heiji: エナメルマトリックスデリバティブ(EMD)を用いた歯周組織再生療法の実際、歯界展望 93(3): 552-566, 1999.

  24. 高野吉郎:電気学会アドバンストマイクロセンサ・プロセス技術調査専門委員会報告書「アドバンストマイクロセンサ・プロセス技術の動向」p. 74-51, 1999

  25. 高野吉郎:細胞がつくる動く縞模様ミクロスコピア 17巻4号:252-257, 2000

  26. 高野吉郎、坂井秀夫、大間範子初期石灰化と添加的石灰化機構の検証
     ーBisphosphonateによる石灰化阻害実験系の解析データからー 解剖誌 75: 351-355, 2000

  27. 高野吉郎:カラーアトラス機能組織学 (Atlas of Functional Histology by Jefferey B Kerr)  藤本豊士,牛木辰男 監訳,南江堂, 2001.
  28. 高野吉郎:カラーエッセンシャル口腔組織・発生学(高野吉郎監訳. 佐々木崇寿, 矢島俊彦, 入江一元訳). 西村書店, 2002.

  29. H Ohshima, K Nakakura-Ohshima, K Takeuchi, M Hoshino, Takano Y and T Maeda: The Pulpal Regeneration after Cavity Preparation, with Special Reference to Close Spatio-relationships between Odontoblasts and Immunocompetent Cells. Microsc. Res. Tech. 60: 483-490, 2003
  30. 高野吉郎: 歯の石灰化 Clinical Calcium (医薬ジャーナル社) 33(9): 81-85, 2003
  31. 高野吉郎(分担) 最新カラー組織学 (L.P. Gartner, J.L. Hyatt) 西村書店


教 授 高野吉郎
Prof. Yoshiro Takano, DDS,Ph.D.



  1. Mechanisms of biological mineralization.
  2. Mechanisms of tooth morphogenesis and development, in search for the mechanisms whereby tooth regeneration is induced.
  3. Mechanisms of cellular calcium regulation and transport in odontogenic tissues and in transport epithelia.
  4. Morphological aspects of immunocompetent cell networks in oral tissues: Its entity and biological function.
  5. Non-genomic regulatory mechanisms of patterning and rhythm generation in biological systems.



【原 著 Articles】

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  1. Sena K, Morotome Y, Baba O, Terashima T, Takano Y, Ishikawa I. Gene Expression of Growth Differentiation Factors in the Developing Periodontium of Rat Molars. J Dent Res 82:166-171,2003.
  2. Sato T, Ono M, Fujita H, Tanaka N, Tomiyama J, Sakamoto Y, Takano Y, Murota S, Morita I. Development of a loquid culture system for megakaryocyte terminal differentiation: fibrinogen promotes megakaryocytopoiesis but not thromboiesis. Brtish J Haematology 121:315-323,2003.
  3. Takano Y, Terashima T, Baba O, Tamaki H, Watanabe E, Nakano Y, Shuda Y and Santiwong P. Induction of functional innovation including mechano-sensory receptors in growing dental and periodontal tissues after ectopic transplantaion of teeth and tooth germs. Regeneration of Oral Tissues; in Cooperative Research Project No.7 in Thailand/Japan Core University Program in Dentistry 43-46,2003.
  4. Nakano Y Kawamoto T, Oda K, Takano Y: Alkaline- and Acid Phosphatase in Bone Cells Serve as Phosphohydrolases at Physiological pH in vivo: A Histochemical Implication. Connective Tissue Research 44(suppl1):219-222,2003.  
  5. Terashima T, Baba O, Takano Y, Ishibashi K, and Oida S: Analysis of Enamel Formation in Mutant Rats with Hypoplastic type of Amelogenesis Imperfecta. Dentistry in Japan 39:8-14,2003.
  6. Takano Y, Sakai H, Watanabe E, Ideguchi-Ohma N, Jayawardena CK, Arai K, Asawa Y, Nakano Y, Shuda Y, Sakamoto Y, and Terashima T: Possible role of dentin matrix on region-specific deposition of cellular and acellular extrinsic fiber cementum.   J Electron Microsc vol.52 (No.6): 573-580, 2003.
  7. JayawardenA CK and .Takano Y: Stage-specific Contribution of Cholinesterase in Amelogenesis of Guinea Pig Teeth .  Archives of Comparative Biology of Tooth Enamel, 8: 16-20, 2003.


  1. Kitahara Y, Suda N, Kuroda T, Beck F, Hammond VE, Takano Y. Disturbed tooth development in parathyroid hormone-related protein (PTHrP)-gene knockout mice. Bone 2002;30:48-56.
  2. Santiwong P, Muramoto T, Soma K, Takano Y. Growth-associated protein-43 immunohistochemical and ultrastructural changes in jaw muscle spindles of the rat following loss of occlusion. Arch Oral Biol 2002;47:227-237.
  3. Jayawardena CK, Takahashi N, Watanabae E, Takano Y. On the origin of intrinsic matrix of acellular extrinsic fiber cementum: studies on growing cementum pearls of normal and bisphosphonate-affected guinea pig molars. Eur J Oral Sci 2002;110:261-269.
  4. Jayawardena CK, Takahashi N, Takano Y. A unique localization of mechanoreceptors in the periodontal tissue of guinea pig teeth. Arch Histol Cytol 2002;65:233-244.
  5. Mekaapiruk K, Suda N, Hammond VE, Beck F, Kuroda T, Takano Y, Terashima. The influence of parathyroid hormone-related protein (PTHrP) on tooth-germ development and osteoclastogenesis in alveolar bone of PTHrP-knock out and wild-type mice in vitro. Arch Oral Biol 2002;47:665-672.
  6. Baba O, Takahashi N, Terashima T, Li W, DenBesten PK, Takano Y. Expression of alternatively spliced RNA transcripts of amelogenin gene exons 8 and 9 and its end products in the rat incisor. J Histochem Cytochem 2002;50:1229-1236
  7. Sakamoto Y, Takano Y. Morphological influence of ascorbic acid deficiency on endochondral ossification in osteogenic disorder Shionogi rat. Anat Rec 2002;268:93-104.
  8. Watanabe E, Takano Y. Ca-binding domains in the odontoblast layer of rat molars and incisors under normal and pathological conditions. Arch Histol Cytol 2002;65:337-346.
  9. Nakano Y, Nomura S, Kawamoto T, Tagami J, Horiba A, Takano Y. An attempt of pH mapping on biological speciments by pH-imaging microscope using a semiconductor silicon sensor, BUNSEKI KAGAKU 2002;51:473-476


  1. Sato Y, Ando T, Takano Y. Demonstration of calcium deposition in duct of submandibular salivary gland using GBHA staining. Hosp. Dent. (Tokyo) 2001; 13: 29-31.
  2. Suda N, Baba O, Udagawa N, Terashima T, Kitahara Y, Takano Y, Kuroda T, Senior PV, Beck F, Hammond VE. Parathyroid hormone-related protein (PTHrP) is required for normal intramembranous bone development. J Bone Miner Res 2001; 16: 2182-2191.
  3. Nakano Y, Kawamoto T, Takano Y. Phosphatase activities of rat intestinal enterocytes and its relation to diverse luminal pH, with special references to possible localization of phytase along brush border membrane. Arch Histol Cytol 2001; 64: 483-492.


  1. Takano Y., Sakai H., Baba O., and Terashima T.: Differential involvement of matrix vesicles during the initial and appositional mineralization processes in bone, dentin and cementum. Bone 26: 333-339, 2000
  2. Satokata I., Ma L., Ohshima H., Bei M., Woo I., Nishizawa K., Maeda T., Takano Y., Uchiyama M., Heaney S., Peters H., Tang Z., Maxxon R., Maas R.: Msx2 deficiency in mice causes pleiotropic defects in bone growth and ectodermal organ formation.
    Nature Genetics, 24: 391-395, 2000
  3. Ohma N., Takagi Y. and Takano Y.: Distribution of noncollagenous dentin matrix proteins and proteoglycans,and their relation to calcium accumulation in the HEBP-affected ratincisors European Journal of Oral Sciences, 108:222-232, 2000
  4. Yazawa H., Takano Y., and Ishikawa I: Time-related changes of developing enamel crystals after exposure to thetissue fluid in vivo: Analysis of subcutaneously implanted rat incisor. Arch. Histol. Cyotol. 63169-179,2000
  5. Muramoto T., Takano Y., and Soma K.: Time-related changes of periodontal mechanoreceptors after loss of occlusalstimuli in rat molars. Arch. Histol. Cyotol. 63: 369-380, 2000
  6. 新井上巳、長澤一雄、山田 格、高野吉郎:オウギハクジラの歯は語る・・・
    エナメル質比較発生学懇話会記録、7: 11-15, 2000.


  1. Ohshima H., Maeda T., and Ohshima H., Maeda T., and Takano Y. :The distribution and ultrastructure of class II MHC-positive cells in human dental pulp. Cell Tissue Res., 259: 151-158, 1999.
  2. Poyapattamin T., Takano Y., Eto K. and Soma K.:Morphological changes in periodontal mechanoreceptors of mouse maxillary incisors after experimental induction of anterior crossbite: a light and electron microscopic observation using immunohistochemistry for PGP 9.5. Eur J Orthodont. 21: 15-29, 1999.
  3. Sakai H., Takano Y., Ohya, K. and Kurosaki N.Intermittent inhibition of dentin mineralization of rat incisors under continual infusion of 1 hydroxyethylidene1, 1-bisphosphonate (HEBP) using subcutaneous mini osmotic pump. Arch. Histol. Cytol. 62: 171-179, 1999.
  4. Yamada H., Maeda T., Hanada K. and Takano Y.: Re-innervation in the canine periodontal ligament of replanted teeth using an antibody to protein gene product 9.5: an immunohistochemical study Endodont Dent Traumatol 15: 221-234, 1999.


  1. Takano Y, Sakai H, Baba O, Sakamoto Y, Terashima T, Ohya K, Kurosaki N: Demonstration of putative Ca-binding domains in the dentin matrix of rat incisors after daily injections of 1-hydroxyethylidene-1,1-bisphosphonate (HEBP). Europian J Oral Sciences, 106(suppl. 1): 274-281. 1998.
  2. Kannari N., Ohshima H., Maeda T., Noda T. and Takano Y.: Class II MHC antigen-expressing cells in the pulp tissue of human deciduous teeth prior to shedding. Arch. Histol. Cytol. 61(1): 1-15 ,1998.
  3. Hanaizumi Y., Maeda T., Takano Y. : Demonstration of possible Ca-mediated binding between bonding material and dentin by two dentin adhesive systems J. Electron Microscopy 47(3):227-41 1998
  4. Ohshima H., Maeda T. and Takano Y.: Cytochrome oxidase activity in the enamel organ during amelogenesis in rat incisors. Anat. Rec., 252(4):519-31. 1998


  1. 高野吉郎:歯と歯周組織の抗原提示細胞ネットワークに関する免疫組織学的、酵素組織化学的研究.文部省科学研究費【基盤研究(B)(2) 07457426】報告書:1997.
  2. Ohtsu, A., Kusakari, H., Maeda, T., Takano, Y.: A histological investigation on tissue responses to titanium-implantation in cortical bone of the rat femur. J. Periodontol. 63( No.3): 270-283, 1997.
  3. Alpaslan, G., Nakajima, T. and Takano, Y.: Extracellular alkaline phosphatase activity as a possible marker for wound healing: A preliminary report.  J. Oral Maxillofac. Surg., 55: 56-62, 1997.
  4. Ohshima Y, Maeda T, Takano Y: Subpopulation of class II MHC antigen-expressing cells in the rat incisor pulp as shown by acid hosphatase histochemistry. Dentistry in Japan 33: 8-14, 1997.
  5. Obinata, K, Ohshima, H, Takano, Y. and Ito, J.: Early ultrastructural changes in the dorsal mucosa of rat tongue after irradiation, with special reference ot the misrovasculature. Radiation Medicine, 15(5): 305-315, 1997.
  6. 高野吉郎、矢沢浩史、馬場麻人:エナメル基質の硬組織形成誘導作用に関する予備的研究, Proceedings: 第1回硬組織再生医工学シンポジウム1997年111,15


  1. 花見重幸,斉藤 功,花田晃治,高野吉郎:実験的歯の移動時における三叉神経節CGRP陽性ニューロンの反応に関する免疫組織化学的研究, 日本矯正歯科学会雑誌55(3): 211-222, 1996.
  2. Takano Y, Hanaizumi Y, and Ohshima H: Occurrence of amorphous and crystalline mineral deposits at the epithelial-mesenchymal interface of calcium-loaded rat incisors: An implication of novel calcium binding domeins.  In: Formation Structure and Composition of Dental Tissues. (ed. by A. Nanci), Anat. Rec., 245: 174-185,1996.  
  3. Sodeyama, T., Maeda, T., Takano, Y. and Hara, K.: Responses of periodontal nerva terminals to experimentally induced occulusal trauma in rat molars: an immunohistochemical study using PGP9.5 antibody. J. Periodont. Res., 31: 235-248, 1996.  
  4. Ohshima, H., Takano, Y., Sato, O., Kawahara, I. and Maeda, T.: Responses of Class II MHC antigen-expressing cells to cavity preparation. Proceedings of the International Conference on Dentin/Pulp Complex 1995, 316-318, 1996.
  5. Hanaizumi, Y., Maeda, T. and Takano, Y.: Three-dimensional arrangement of enamel prisms and their relation to the formation of Hunter-Schreger bands. Cell Tissue Res., 286:103-114, 1996
  6. Takano, Y., Kawahara, Hoshino, M., Takeuchi, K., Maeda, T., Ohshima, H., Hanaizumi, Y. and Kawano, Y.: Dendritic Cells: A Novel Cellular Component of the Rat Incisor Enamel Organ Appearing in the Late Stages of Enamel Maturation. Advances in Dent. Res., 10 (2) 95-104, 1996.


  1. Ohshima, H., Sato, O., Kawahara, I., Maeda, T. and Takano, Y.: Responses of immunocompetent cells to cavity preparation in rat molars: An immunohistochemical study using OX6-monoclonal antibody. Connective Tissue Res., 32(1-4):303-311, 1995.
  2. Kawahara, I. and Takano, Y.: Immunohistochemical characterization and localization of immunocompetent cells in the periodontal ligament of rat incisors. Connective Tissue Res., 33(1-3):369-378, 1995.
  3. Kawahara, I. and Takano, Y.: Segregated localization of immunocompetent cells and osteoclasts in the periodontal ligament of rat molar tooth. Arch. Histol. Cytol. 58(3):345-355, 1995.
  4. 花泉好訓,河野芳朗,高野吉郎:イヌのハンターシュレーゲル条の三次元的観察,エナメル質比較発生学懇話会記録 4:31-44, 1995.
  5. Nakakura-Ohshima, K., Maeda, T., Ohshima, H., Noda, T. and Takano, Y.: Postnatal development of periodontal Ruffini endings in rat incisors: An immunoelectron microscopic study using protein gene product 9.5 (PGP 9.5)-antibody. J. Comp. Neurol. 362:551-564, 1995.


  1. Maeda, T., Sodeyama, T., Hara, T. and Takano, Y.: Evidence for the existence of intraepithelial nerve endings in the junctional epithelium of rat molars: an immunohistochemcal study using protein gene product 9.5 (PGP9.5) antibody. J. Periodont. Res., 29:377-385, 1994.
  2. Maeda, T., Homma, S. and Takano, Y.: Dense innervation of human radicular dental pulp as revealed by immunocytochemistry for protein gene-product 9.5. Archs Oral Biol., 39(7):563-568, 1994.
  3. 田口直行、草刈 玄、高野吉郎: GTR法による骨増生に関する形態学的研究ー特にコラーゲン製材の効果についてー、補綴誌, 38:596-610, 1994.
  4. 小林龍彰、大橋 靖、前田健康、高野吉郎: ラット顎関節の神経支配ー抗PGP9.5血清を用いた免疫組織化学的研究ー、口科誌, 43(3):369-385, 1994.
  5. Amin, N., Ohashi, Y., Chiba, J., Yoshida, S. and Takano, Y.: Alterations in vascular pattern of the developing palate in normal and spontaneous cleft palate mouse embryos. Cleft Palate-Craniofacioal J., 31(5):332-344, 1994.
  6. Sato, Y., Noguchi, I., Ando, T., Kurokawa, H., Takahashi, M., HInata, H. and Takano, Y.: Histochemical demonstration of calcium in the rat submandibular gland under normal and pathological conditions by use of GBHA. Jpn. J. Oral Diag/Oral Med., 7(2):409-413, 1994.
  7. Ohshima, H., Kawahgara, I., Maeda, T. and Takano, Y.: The relationship between odontoblasts and immunocompetent cells during dentinogenesis in rat incisors: an immunohistochemical study using OX6-monoclonal antibody. Arch.Histol. Ctyol., 57(5):435-448, 1994.
  8. 高野吉郎: 歯と歯周組織形成細胞のカルシウム制御機構に関する組織化学的、免疫細胞化学的研究.文部省科学研究費【一般研究A04404069】報告書:1994.


  1. 澤田雅仁、草刈 玄、佐藤 修、前田健康、高野吉郎: インプラント周囲組織の経時的変化 ー特に神経線維の動態についてー. 日本歯科補綴学会雑誌 37(1):144-158, 1993.
  2. Maeda, T., Sato, O., Takano, Y.: Cytochrome oxidase activity as a marker for periodontal sensory receptors. Archs Oral. Biol., 38(3):255-259, 1993.
  3. Maeda, T., Sato, O., Kawahara, I. and Takano, Y.: Histochemical demonstration of acid phosphatase activity in periodontal Ruffine endings in rat incisors. Archs. Oral Biol., 38(7): 611-617, 1993.
  4. Kannari, K., Maeda, T., and Takano, Y.: Sinusoidal vessels in the periodontal ligament of hamster incisors: Their distribution, structure and possible function. Arch. Histol. Cytol. 56:91-99, 1993.
  5. Jikko, A., Aoba, T., Murakami, H., Takano, Y., Iwamoto, M. and Kato, Y.: Characterization process in cultures of rabbit growth plate chondrocytes. Developmental Biol. 156:372-380. 1993.
  6. Takano, Y. and Ohshima, H.: Histochemical demonstration of calcium phosphate depositions in the enamel organ of calcium-loaded tooth germs of the rat. Arch. Comp. Biol. Tooth Enamel. 3:57-64, 1993.
  7. Takano, Y., Sato, O., Ohshima, H., Maeda, T., Kawahara, I. and Noguchi, I.: Histochemical localization and X-ray microanalysis of oalcium in the submandibular gland of normal rat: Demonstration of possible sites for microlith induction. Arch. Histol. Cytol., 56(2):1770184, 1993.
  8. Nakakura-Ohshima, K., Maeda, T., Sato, O. and Takano, Y.: Postnatal development of periodontal innervation in rat incisors: Ana immunohistochemical study using protein gene product 9.5 antibody. Arch. Histol. Cytol., 56(4):385-389, 1993.
  9. Takano, Y., Ohshima, H., Maeda, T. and Sato, O.: GBHA staining method: Its application to demonstration of cytoplasmic calcium stores in some exocrine and endocrine glands. J. Hard Tissue Biol., 2(2):20-27, 1993.


  1. Takano, Y., Crenshaw, M.A. and Bawden, J.W.: Calcium movement in vivo and in vitro in secretory stage enamel of rat incisors. Archs Oral Biol., 37(5):377-383, 1992.
  2. Maeda, T., Sato, O., Iwanaga, T. and Takano, Y.: Immunocytochemical localization of nerve growth factor receptor (NGFR) in human teeth. Proc. Finnish Dent. Res., 268:51-63, 1992
  3. Sato, O., Maeda, T., Kannari, K., Iwanaga, T. and Takano, Y.: Innervation of the periodontal ligament in the dog with special reference to the morphology of Ruffini endings. Arch. Histol. Cyotl., 55(1):21-30, 1992.
  4. Kawahara, I., Takano, Y., Sato, O,. Maeda, T and Kannari K.: Histochemical and immunohistochemical demonstration of macrophages and dendritic cells in the lingual periodontal ligament of rat incisors. Arch. Histol. Cytol., 55(2):211-217, 1992.
  5. Takano, Y.: Histochemical demonstration and microanalysis of possible calcium binding sites in the enamel organ of rat incisors. Scanning Microscopy, 6(3):773-784, 1992.
  6. Sato, O., Kakeuchi-Maeno, H., Maeda, T. and Takano, Y.: Immunoelectron microscopic observation of calcitonin gene-related peptide (CGRP)-positive nerve endings in rat molar teeth. Arch. Histol. Cytol. 55(5):561-568, 1992.


  1. Wakita, M. and Takano, Y.: Structure and calcification of enamel matrix of Paralichtys olivaceus. Arch. Comp. Biol. Tooth Enamel 2:13-16, 1991
  2. 高野吉郎、脇田 稔:ラット切歯エナメル器におけるミトコンドリアの分布と微小環境のカルシウム濃度、エナメル質比較発生学懇話会記録 2:29-32, 1991
  3. Hashimoto Y, Takano Y, Seto T, Watanabe S, Araki S.A case of bilateral cerebellar infarction in the distribution of the bilateral superior cerebellar artery Rinsho Shinkeigaku. 1991 Nov;31(11):1241-4. Japanese.


  1. Takano Y, Yamamoto T, Domon T, Wakita M. Histochemical, ultrastructural, and electron microprobe analytical studies on the localization of calcium in rat incisor ameloblasts at early stage amelogenesis. Anat Rec. 1990 Oct;228(2):123-31.
  2. Takano Y, Hanawa M, Yamamoto T, Domon T, Fujinami H, Hanaizumi Y, Wakita M. Time-related changes in the distribution of 45Ca in the developing enamel of rat incisors as revealed by radioautography. J Biol Buccale. 1990 Jun;18(2):135-47.
  3. Takano Y, Matsuo S, Wakisaka S, Ichikawa H, Nishikawa S, Akai M. Histochemical localization of calcium in the enamel organ of rat incisors in early-stage amelogenesis. Acta Anat (Basel). 1989;134(4):305-11.


  1. Matsuo S, Nakahara H, Takano Y, Ichikawa H, Wakisaka S, Akai M. Localization of two distinct acid phosphatases in secretory ameloblasts of rat molar tooth germs. Arch Oral Biol. 1989;34(8):599-608.
  2. Ichikawa H, Nishikawa S, Wakisaka S, Matsuo S, Takano Y, Akai M. Substance-P-like immunoreactive subepithelial nerve plexuses in the labial mucosa of the mouse. Acta Anat (Basel). 1989;134(4):283-5.


  1. Matsuo S, Takano Y, Wakisaka S, Ichikawa H, Nishikawa S, Akai M. Budding of small vesicles from the rough-surfaced endoplasmic reticulum in secretory ameloblasts of rat molar tooth germs. Anat Rec. 1988 Dec;222(4):317-22.
  2. Takano Y, Matsuo S, Ichikawa H, Akai M, Itotagawa T, Kato J. Indirect visualization of the ameloblast modulation in porcine molar tooth germs by EDTA etching and GBHA staining methods. J Osaka Univ Dent Sch. 1988 Dec;28:63-72.
  3. Matsuo S, Takano Y, Wakisaka S, Ichikawa H, Nishikawa S, Akai M. Effect of colchicine on the transport of precursor enamel protein in secretory ameloblasts studied by 3H-proline radioautography in vitro. Anat Rec. 1988 Aug;221(4):812-22.
  4. Ichikawa H, Nishikawa S, Wakisaka S, Matsuo S, Takano Y, Akai M. Coexistence of vasoactive intestinal polypeptide- and substance P-like immunoreactivities in the tongue of the guinea pig. Neurosci Lett. 1988 Jul 8;89(3):283-5.
  5. Takano Y, Matsuo S, Wakisaka S, Ichikawa H, Nishikawa S, Akai M. A histochemical demonstration of calcium in the maturation stage enamel organ of rat incisors. Arch Histol Cytol. 1988 Jul;51(3):241-8.
  6. Wakisaka S, Ichikawa H, Nishikawa S, Matsuo S, Takano Y, Akai M. Neurokinin A-like immunoreactivity in feline dental pulp: its distribution, origin and coexistence with substance P-like immunoreactivity. Cell Tissue Res. 1988 Mar;251(3):565-9.
  7. Matsuo S, Takano Y, Wakisaka S, Ichikawa H, Nishikawa S, Itotagawa T, Akai M. Cytochemical study of the Golgi apparatus and related organelles of the secretory ameloblasts of rat molar tooth germs cultured with and without colchicine. Arch Oral Biol. 1988;33(6):433-41.
  8. Takano Y, Matsuo S, Wakisaka S, Ichikawa H, Nishikawa S, Akai M. Cyclic changes in the properties of maturing enamel in the bovine permanent incisor as revealed by glyoxal bis(2-hydroxyanil) staining. Arch Oral Biol. 1988;33(4):231-6.
  9. Takano Y, Akai M. Histochemical, ultrastructural and X-ray microprobe analytical studies of localization of calcium in the mucous lining of the rat duodenum. Histochemistry. 1988;89(5):429-36.
  10. Ichikawa H, Nishikawa S, Wakisaka S, Matsuo S, Takano Y, Akai M. Occurrence of substance P-like immunoreactive nerve fibers in Krause corpuscles of the dog's tongue. Acta Anat (Basel). 1988;131(3):215-7.


  1. Takano Y, Matsuo S, Wakisaka S, Ichikawa H, Nishikawa S, Itotagawa T, Akai M. Vascular perfusion studies of the influence of levamisole on calcium influx into the maturing enamel of rat incisors. J Osaka Univ Dent Sch. 1987 Dec;27:51-64.  
  2. Takano Y, Akai M, Matsuo S, Wakisaka S, Ichikawa H, Nishikawa S. Temperature-related ultrastructural changes in early stage amelogenesis in vascularly perfused rat incisors. Adv Dent Res. 1987 Dec;1(2):371-9.
  3. Takano Y, Matsuo S, Wakisaka S, Ichikawa H, Nishikawa S, Akai M. The influence of vanadate on calcium uptake in maturing enamel of the rat incisor. J Dent Res. 1987 Dec;66(12):1702-7.
  4. Takano Y, Akai M. Demonstration of Ca2+-ATPase activity in the maturation ameloblast of rat incisor after vascular perfusion. J Electron Microsc (Tokyo). 1987;36(4):196-203.  
  5. Wakisaka S, Ichikawa H, Nishikawa S, Matsuo S, Takano Y, Akai M. Immunohistochemical observation on the correlation between substance P- and vasoactive intestinal polypeptide-like immunoreactivities in the feline dental pulp. Arch Oral Biol. 1987;32(6):449-53.
  6. Wakisaka S, Ichikawa H, Nishikawa S, Uchiyama T, Matsuo S, Takano Y, Akai M. Immunohistochemical study on regeneration of substance P-like immunoreactivity in rat molar pulp and periodontal ligament following resection of the inferior alveolar nerve. Arch Oral Biol. 1987;32(3):225-7.
  7. Wakisaka S, Ichikawa H, Nishikawa S, Matsuo S, Takano Y, Akai M. The distribution and origin of calcitonin gene-related peptide-containing nerve fibres in feline dental pulp. Relationship with substance P-containing nerve fibres. Histochemistry. 1987;86(6):585-9.


  1. Matsuo S, Yamamoto K, Nishikawa S, Ichikawa H, Wakisaka S, Takano Y, Akai M. Influence of colchicine on the distribution of horseradish peroxidase in the secretory ameloblast layer in vitro. Anat Rec. 1986 Sep;216(1):10-8.
  2. Takano Y, Ozawa H, Crenshaw MA. Ca-ATPase and ALPase activities at the initial calcification sites of dentin and enamel in the rat incisor. Cell Tissue Res. 1986;243(1):91-9.


  1. Wakisaka S, Nishikawa S, Ichikawa H, Matsuo S, Takano Y, Akai M. The distribution and origin of substance P-like immunoreactivity in the rat molar pulp and periodontal tissues. Arch Oral Biol. 1985;30(11-12):813-8.


  1. Takano Y, Crenshaw MA, Bawden JW, Hammarstrom L, Lindskog S. The visualization of the patterns of ameloblast modulation by the glyoxal bis(2-hydroxyanil) staining method. J Dent Res. 1982 Dec;Spec No:1580-7.
  2. Takano Y, Crenshaw MA, Reith EJ. Correlation of 45Ca incorporation with maturation ameloblast morphology in the rat incisor. Calcif Tissue Int. 1982 Mar;34(2):211-3.


  1. Takano Y, Ozawa H. Cytochemical studies on the ferritin-containing vesicles of the rat incisor ameloblasts with special reference to the acid phosphatase activity. Calcif Tissue Int. 1981;33(1):51-5.


  1. Takano Y, Ozawa H. Ultrastructural and cytochemical observations on the alternating morphologic changes of the ameloblasts at the stage of enamel maturation. Arch Histol Jpn. 1980 Dec;43(5):385-99.
  2. Takano Y, Crenshaw MA. The penetration of intravascularly perfused lanthanum into the ameloblast layer of developing rat molar teeth. Arch Oral Biol. 1980;25(8-9):505-11.


  1. Takano Y. Cytochemical studies of ameloblasts and the surface layer of enamel of the rat incisor at the maturation stage. Arch Histol Jpn. 1979 Jan;42(1):11-32.