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Tokyo Medical and Dental University, Faculty of Dentistry

Tokyo Medical and Dental University, Faculty of Dentistry

Research subjects of each section

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Course:Oral Health Sciences
Department	Course	Chief faculty	Research subject
Oral Restitution	Oral Pathology	Akira Yamaguchi	･Clinico-pathological studies on oral lesions ･Molecular mechanism of bone regeneration ･Notch signaling in embryogenesis and regeneration
	Molecular Cellular Oncology and Microbiology	Nobuo Tsuchida	･Cell signaling control of cell growth and death ･Cytopathic factor of periodontpathic bacteria ･Suppression of tumor growth by oligonucleotides
	Molecular Immunology	Miyuki Azuma	･Mechanism of immune responses in oral diseases ･Studies on lymphocyte functional molecules ･Immunotherapy by molecular targetting
	Oral Radiation Oncology	Masahiko Miura	･Radiosensitization mechanism by sulfoglycolipids ･Radiation-induced senescence-like phenotype ･Effect of IGF-I receptor expression on tumor microenvironment
	Oral and Maxillofacial Surgery	Ken Omura	･Clinical and basic study on oral cancer ･Clinical and basic study on dentofacial deformity ･Clinical and basic study on reconstruction and regeneration of jaw bone
	Oral and Maxillofacial Radiology	Toru Kurabayashi	･Improvement of efficarcy of maxillofacial imaging ･Novel MRI techniques for maxillofacial diagnosis ･Molecular mechanisms of cellular radiosensitivity
	Anesthesiology and Clinical Physiology	Masahiro Umino	･Development of drug delivery system using alternating current ･Study of diffuse noxious inhibitory control ･Elucidation of pathogenesis in neuropathic pain
	Orofacial Pain Management	Masahiko Shimada	･New treatment methods for neuropathic pain ･Analyses of abnormal orofacial sensations ･Analyses and new treatments of dysgeusia
	Diagnostic Oral Pathology	Norihiko Okada	･Clinicopathological Study on tumors of oral tissues ･Immunopathological study on oral mucosal diseases ･Clinicobacteriological study of oral infections
Orofacial Development and Function	Developmental Oral Health Sciences	Yuzo Takagi	･Tooth development and its disturbance ･Stomatognathic function of children ･Growth of dento-maxilofacial complex
Orofacial Development and Function	Orthodontic Science	Kunimichi Soma	･Orthodontical studies on occlusal function ･Pathophysiological studies on malocclusion ･Biological studies on functional adaptation
Restorative Sciences	Cariology and Operative Dentistry	Junji Tagami	･Development and evaluation of dental adhesive ・Studies on caries prevention, diagnosing and treatment ・Development of aesthetic dental treatments
	Fixed Prosthodontics	Hiroyuki Miura	･Occlusion of crown-bridge restorations ･Clinical studies on new equipment and materials ･Systemic affects of materials for crown-bridge
	Pulp Biology and Endodontics	Hideaki Suda	･Molecular biology of pulp and periapical tissues ･Neurophysiology of dental pain ･Application of lasers to endodontics
	Advanced Biomaterials	Hidekazu Takahashi	･Factors affecting mechanical properties of dentin ･Evaluation of fatigue behavior of dental ceramics ･Development of durable dental composite resins
Masticatory Function Rehabilitation	Removable Partial Denture Prosthodontics	Yoshimasa Igarashi	･Evaluation of stomatognathic system after tooth loss ･Development of innovative removable prosthodontics ･Evaluation of restorations for partially edentulous patients
	Complete Denture Prosthodontics	Under Selection	･Oral function improvement by roofless denture ･Nonsupporting implant overdenture system ･Development of denture materials
	Oral Implatology and Regenerative Dental Medicine	Shohei Kasugai	･Improvement of biocompatibility of dental implant ･Dental implant and its surrounding tissues ･Regeneration of bone and periodontal tissues

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Course:Maxillofacial/Neck Reconstruction
Department	Course	Chief faculty	Research subject
Maxillofacial Biology	Maxillofacial Anatomy	Yasuo Yamashita	･Comparative histology and embryology of teeth ･Histogenesis of periodontal tissue ･Morphological features of jaw bone
	Cognitive Neurobiology	Atsushi Iriki	･Mechanism of concept formation based on body image ･Neural mechanism of tactile object exploration ･Processing of vocalizations in auditory cortex
	Molecular Embryology	Under Selection	･Gene expression in cell growth and differentiation ･Cell plasticity in regeneration and cancer ･Craniofacial development and anomalies
	Cellular Physiological Chemistry	Ikuo Morita	･Regulation of diseases by controlling angiogenesis ･Study for connexins and gap junction ･Molecular aspects of inflammation
	Molecular Neurobiology	Shuichi Nozaki
Maxillofacial Reconstruction and Function	Maxillofacial Surgery	Teruo Amagasa	･Research for oral cancer and precancer ･Research for cleft lip & palate and facial deformity ･Molecular biology of oral diseases
	Maxillofacial Orthognathics	Keiji Moriyama	･Orthodontic treatments for birth defect and jaw deformity patients ･Investigation of disease genes for birth defects ･Brain imaging of oral and maxillo-facial function
	Maxillofacial Prosthetics	Hisashi Taniguchi	･Diagnosis for maxillofacial prosthetic treatment ･Development of materials for maxillofacial prosthetic treatment ･Acoustic analysis of speech and voice
	Dentistry for Persons with Disabilities	Tsuneyoshi Yamazaki	･Study on oral biofilm formation ･Study on drug-induced gingival overgrowth ･Toothbrush with irrigation and suctioning function

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Course:Bio-Matrix
Department	Course	Chief faculuty	Research subject
Hard Tissue Engineering	Biostructural Science	Yoshiro Takano	･Mechanisms of biological mineralization ･Molecular mechanisms of tooth development and evolution ･Regeneration of dental and periodontal tissues
	Pharmacology	Keiichi Ohya	･Drug effects on the formation of teeth and bone ･Pharmacological analysis of bone resorption ･Development of inhibitors for bone resorption
	Tissue Regeneration	Tamayuki Shinomura	･Study of chondrogenic differentiation ･Maintenance mechanisms of chondrogenic phenotype ･Study of extracellular matrix
	Biochemistry	Masaki Yanagishita	･Functions and regulation of extracellular matrix ･Sphingolipid signaling for survival of B cells ･Bone and central nervous system in weightlessness
	Cell Signaling	Hiroshi Takayanagi	･Signal transduction in osteoclasts and osteoblasts ･Interaction between the immune system and bone ･Novel therapies for rheumatoid arthritis
	Periodontology	Yuich Izumi	･Etiology, host responses and periodontal medicine ･Periodontal regeneration by cell sheet engineering ･Clinical application of laser in periodontics

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Course:Oral Health Sciences
Department	Course	Chief faculty	Research subject
International Health Development	Oral Health Promotion	Yoko Kawaguchi	･Epidemiology and oral disease prevention ･Community dentistry and oral health promotion ･International studies on oral health
	Sports Medicine/Dentistry	Toshiaki Ueno	･Improvement of oral health care for athletes ･Oral functions and body motor functions ･Prevention of oral injuries and mouthguards
	Forensic Dentistry	Under selection	･Judicial autopsy ･Forensic pathology ･Forensic dentistry
Health Science Policies	Health Care Economics	Koichi Kawabuchi	･Research on health care economics ･Research on health care management ･International comparison on health care reform
	Dental Education Development	Ikuko Morio	･Comparative study of dental education ･Research projects for dental students ･English education programs for dental students
	Health Policy and Management in Dentistry	Under selection	･Planning and evaluation of oral health policy based on EBM ･Application of epidemiology and statistics to dentistry ･Application of the results of medical-dental collaboration to policy making
	Educational System in Dentistry	Kouji Araki	･Development of evaluation method in dental curriculum ･Validity and reliability of evaluation system for dental education ･Evaluation of international educational standard

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Course:Gerontology and Gerodontology
Department	Course	Chief faculty	Research subject
Gerodontology	Gerodontology	Hiroshi Uematsu	･Oral function related aging ･Eating disorder of the aged ･Medical management during dental treatment

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Course:Comprehensive Patient Care
Department	Course	Chief faculty	Research subject
Comprehensive Oral Health Care	General Dentistry	Norimasa Kurosaki	･Study on new diagnosis of sleep apnea syndrome ･Study on improvement of dental restorative material ･Study of chemo-mechanical carious removal method
	Head and Neck Psychosomatic Medicine	Akira Toyofuku	･Study on pathophysiological mechanisms of oral psychosomatic disorders ･Psychosomatic study on oro-facial unidentified complaints such as dysaesthesia and chronic pain ･Application and research of various psychotherapies and psychopharmacological therapies for the treatment of oral psychosomatic disorders
	Behavioral Dentistry	Shiro Mataki	･Communication ability in clinical dentistry ･Application of behavioral sciences to education ･Stress assessment of patients and medical staff
	Temporomandibular Joint and Occlusion	Kouji Kino	･Study for factors of temporomandibular disorders ･Study for psychosomatic factors of TMD patients ･Study of modifying factors for sleep bruxism

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Donated Departments
Department	Course	Chief faculty	Research subject
Donated Depertments	Department of Nanomedicine（DNP）	Mayumi Abe	･Regeneration of vascular system ･Regeneration of periodontal ligament ･Molecular mechanism of angiogenesis
	Department of Sleep-Related Respiratory Disorders	Makoto Hasegawa	･Sleep apnea syndrome and maxillofacial factors ･The study for the development of sleep splint ･The study of dental approach in sleep apnea
	Department of Natural Resources and Physiological Chemistry	Takahiro Sato	･Exploration and analysis of natural bioproducts ･Fusion of cellular biology and natural chemistry ･Education for dental advisory stuff in supplements