Topics 2020.09.23 Wed Admissions Frosted branch angiitis after allogeneic haematopoietic stem cell transplantation in adult T-cell leukaemia-lymphoma 2020.09.11 Fri Admissions Age-dependent and seasonal changes in menstrual cycle length and body temperature based on big data 2020.07.27 Mon Admissions Targeting all transforming growth factor-β isoforms with an Fc chimeric receptor impairs tumor growth and angiogenesis of oral squamous cell cancer 2020.07.21 Tue Admissions A new molecular guardian of intestinal stem cells 2020.07.14 Tue Admissions Shigella prevents infected cells from sacrificing themselves for the greater good 2020.06.02 Tue Admissions In vitro neo-genesis of tendon-like tissue by combination of Mohawk and a three-dimensional cyclic mechanical stretch culture system 2020.06.01 Mon Admissions “Opening of an open-laboratory for research into next generation ventilators, and for evaluation and research, etc. of new ventilator types, with a view towards responding to the surge in numbers of novel coronavirus patients” 2020.06.01 Mon Admissions Lin28a/let-7 Pathway Modulates the Hox Code via Polycomb Regulation during Axial Patterning in Vertebrates 2020.05.25 Mon Admissions Characterization of radioresistant epithelial stem cell heterogeneity in the damaged mouse intestine 2020.05.22 Fri Admissions How Stress Affects Bone Marrow 2020.02.27 Thu News "Research Activities 2020" issued. 2020.02.12 Wed Admissions A Joint Clinical Research Collaboration among Tokyo Medical and Dental University (TMDU), ACT Genomics , and ACTmed Seeks to Investigate the Cancer Genomic Landscape of Japanese Population 2020.01.28 Tue Admissions All screen print Text print YAP-dependent necrosis occurs in early stages of Alzheimer's disease and regulates mouse model pathology 2020.01.28 Tue News Protection of a qubit via subradiance: A Josephson quantum filter 2020.01.15 Wed News A Novel, Tumor-Induced Osteoclastogenesis Pathway In sensitive to Denosumab but Interfered by Cannabidiol 2020.01.08 Wed News Therapeutic Potential of LNP-Mediated Delivery of miR-634 for Cancer Therapy 2020.01.08 Wed News Vpu of a Simian Immunodeficiency Virus Isolated from Greater Spot-Nosed Monkey Antagonizes Human BST-2 via Two AxxxxxxxW Motifs 2019.12.25 Wed Admissions Transcutaneous blood VOC imaging system (skin-gas cam) with real-time bio-fluorometric device on rounded skin surface 2019.12.25 Wed News Kickoff Symposium for the Medical Innovation Consortium held 2019.12.25 Wed News Transcutaneous blood VOC imaging system (skin-gas cam) with real-time bio-fluorometric device on rounded skin surface 2019.12.23 Mon News Intracellular claudin‐1 at the invasive front of tongue squamous cell carcinoma is associated with lymph node metastasis 2019.11.27 Wed News Temporospatial sonic hedgehog signalling is essential for neural crest-dependent patterning of the intrinsic tongue musculature 2019.11.07 Thu News 18th Surugadai International Symposium & Joint Usage/Research Program of Medical Research Institute International Symposium(2019.11.18) 2019.11.06 Wed Admissions Bile duct biomarker? Protein found to pinpoint patients with a lethal cancer 2019.11.01 Fri News A Nice Reactive Ring to It: New Synthetic Pathways for Diverse Aromatic Compounds 2019.10.21 Mon Admissions “Instant Liver, Just Add Water”? Not Quite, but a Better Way to Grow Multiple Organs 2019.09.24 Tue News Comparative analysis demonstrates cell type-specific conservation of SOX9 targets between mouse and chicken 2019.09.11 Wed News Stem cell competition offers a mechanism for skin youthfulness and ageing 2019.08.06 Tue News Heterogeneity in fetal growth velocity 2019.08.02 Fri News 3D miniature livers lead the way to patient-specific drug discovery 2019.07.30 Tue News Involvement of N-type Ca2+ channel in microglial activation and its implications to aging-induced exaggerated cytokine response 2019.07.24 Wed News "HDO-antimiR represents a new weapon in the fight against microRNA-related disease" 2019.07.04 Thu Admissions Enhancement of Motor Function Recovery After Spinal Cord Injury in Mice by Delivery of Brain Derived Neurotrophic Factor mRNA 2019.07.03 Wed Admissions Fibroblast growth factor signals regulate transforming growth factor‐β‐induced endothelial‐to‐myofibroblast transition of tumor endothelial cells via Elk1 2019.07.01 Mon News Tolvaptan activates the Nrf2/HO-1 antioxidant pathway through PERK phosphorylation 2019.06.28 Fri Admissions 3-Thioaryne Intermediates for the Synthesis of Diverse Thioarenes 2019.06.25 Tue News Blockade of microglial Cav1.2 Ca2+ channel exacerbates the symptoms in a Parkinson’s disease model 2019.06.19 Wed News Highly efficient silencing of microRNA by heteroduplex oligonucleotides. 2019.06.13 Thu News Reciprocal cortical activation patterns during incisal and molar biting correlated with bite force levels: an fMRI study. 2019.06.07 Fri News Nature Medicine is focusing on Prof.Takanori Takebe (Organ and Tissue Neogenesis Consortium, Institute of Research) . 2019.06.07 Fri News A Review Article, “Organoid by Design”, by Prof.Takanori Takebe (Organ and Tissue Neogenesis Consortium, Institute of Research) has been published on Science. 2019.06.05 Wed News MRTF A regulates proliferation and survival properties of pro atherogenic macrophages 2019.06.04 Tue News Wwp2 maintains cartilage homeostasis through regulation of Adamts5. 2019.05.31 Fri News Modeling Steatohepatitis in Human with Pluripotent Stem Cell-Derived Organoids 2019.05.29 Wed News Antibacterial activity of lysozyme-chitosan oligosaccharide conjugates (LYZOX) against Pseudomonas aeruginosa, Acinetobacter baumannii and Methicillin-resistant Staphylococcus aureus 2019.05.10 Fri News “Hard food, strong jaw: jawbone structure responds to forceful chewing” 2019.04.23 Tue News Synthesis of Alkynyl Sulfides by Copper-Catalyzed Thiolation of Terminal Alkynes Using Thiosulfonates 2019.04.16 Tue News Silencing of PD-L2/B7-DC by Topical Application of Small Interfering RNA Inhibits Elicitation of Contact Hypersensitivity 2019.04.16 Tue News ”Genome editing helps decipher a congenital liver disease” 2019.04.16 Tue Admissions Silencing of PD-L2/B7-DC by Topical Application of Small Interfering RNA Inhibits Elicitation of Contact Hypersensitivity 2019.04.12 Fri News Development of a NanoBRET-based Sensitive Screening Method for CXCR4 Ligands 2019.04.10 Wed News Impact of novel NS5A resistance-associated substitutions of hepatitis C virus detected in treatment-experienced patients 2019.04.04 Thu News Stem cell competition orchestrates skin homeostasis and ageing 2019.03.28 Thu News Vol.11 of our public relations magazine 'TMDU ANNUAL NEWS' issued 2019.03.20 Wed News Forceful mastication activates osteocytes and builds a stout jawbone 2019.03.12 Tue News "Research Activities 2019" issued. 2019.03.11 Mon News TMDU is ranked 1st (Dentistry in Japan) and 3rd (Medicine in Japan) in QS World University Rankings 2019 by Subject! 2019.01.18 Fri News "The clock components Period2, Cryptochrome1a, and Cryptochrome2a function in establishing light-dependent behavioral rhythms and/or total activity levels in zebrafish" 2018.03.31 Sat News Vol.10 of our public relations magazine 'TMDU ANNUAL NEWS' issued 2018.03.24 Sat News "TMDU Research Activities 2018" issued. 2017.12.27 Wed News "Alzheimer’s Disease Pathway Identification Enables Development of Novel Preclinical Therapy" 2017.07.14 Fri News "Reduced mastication results in the impairment of memory and learning function" 2017.07.14 Fri Admissions The 562th Medical Research Institute Seminar, The 135th Joint Usage/Research Program of Medical Research Institute Seminar「Epilepsies linked to mTOR1 pathway」 2017.06.13 Tue Admissions "Discovery of Human Blood Cell Destinies Revises Knowledge of Immune Cell Development" 2017.06.12 Mon News "A Lightning-Fast Flu Virus Detector" 2017.05.09 Tue News International Conference for Precision Cancer Medicine 2017 (Thu 29 Jun - Fri 30 Jun 2017) 2017.03.30 Thu Admissions "Differences in Microbial Interactions Underlie Related Oral Diseases" 2017.03.30 Thu Admissions "Method Identified to Boost Detection of Highly Cancerous Stem Cells" 2017.03.28 Tue News Vol.2 of our New publication specialized in our research activities TMDU Research Activities 2017 issued 2017.03.28 Tue News Vol 9 of our public relations magazine 'TMDU ANNUAL NEWS' issued 2017.03.24 Fri News "New Synthetic Route to Complex Organofluorine Compounds Developed" 2017.01.17 Tue News "Metabolic Pathway Regulating Key Stage of Embryo Development Revealed" 2016.12.28 Wed News "Role of Sox17 Protein in Embryo Implantation Key to Mouse Fertility" 2016.12.27 Tue Admissions "All screen print Text print "Alzheimer’s Disease Pathway Identification Enables Development of Novel Preclinical Therapy" 2016.12.16 Fri Admissions "Degrader of Proteins Required for the Origin of Early Cancerous Lesions" 2016.12.14 Wed Admissions "Breakthrough in Hepatitis Research as New Infected Cell Models are Developed" 2016.11.24 Thu Admissions "Novel Method of Cellular Waste Disposal Revealed in Yeast and Mammals" 2016.11.24 Thu Admissions ”Role for Autophagic Cellular Degradation Process in Maintaining Genomic Stability” 2016.11.22 Tue Admissions ”Novel Type of Cell Death in Huntington’s Disease May Lead to Effective New Therapies” 2016.11.22 Tue News "How Cell Populations Weed Out “Loser” Cells to Maintain Vitality is Revealed" 2016.11.01 Tue News "Advancing Our Understanding of How the Disease Lupus is prevented in healthy individuals" 2016.10.05 Wed Admissions “Breakthrough for Bone Regeneration via Double-cell-layered Tissue Engineering Technique” 2016.07.01 Fri News “Blood Coagulation Detector May Help in Monitoring Stroke Risk” 2016.06.07 Tue Admissions “World's First Measurement and Visualization of Cardiac Activity Using MR Sensors” 2016.03.30 Wed News Vol 1 of our New publication specialized in our research activities 'TMDU Research Activities 2016' issued 2016.03.28 Mon News Vol 8 of our public relations magazine 'TMDU ANNUAL NEWS' issued 2016.02.16 Tue Admissions “Periodic injections of synovial stem cells inhibit osteoarthritis progression in the knee” 2016.02.01 Mon Admissions “Synthetic polymer-based elucidation of survival strategies of cancer stem cells” 2015.12.28 Mon Admissions “Tooth regenerative technology by a mechanical ligation method” 2015.09.29 Tue Admissions Tokyo Medical and Dental University to establish an INCJ-backed venture company, Rena Therapeutics Inc. 2015.08.11 Tue Admissions “DNA/RNA Heteroduplex oligonucleotide: the third class oligonucleotides” 2015.05.12 Tue News TMDU ranked #1 in the Nation and #6 in the World in Dentistry by QS World University Rankings 2015.04.30 Thu Admissions “Highly efficient CRISPR knock-in in mouse” 2015.04.01 Wed News Vol 7 of our public relations magazine 'TMDU ANNUAL NEWS' issued 2014.12.16 Tue Admissions “Gene therapy of model mice for spinocerebellar ataxia was successful.” 2014.08.18 Mon Admissions “Transplanting Cultured Small Intestinal Epithelial Stem Cells onto Colon” 2014.07.09 Wed News The Program for Promoting the Enhancement of Research Universities ( from TMDU Annual News ) 2014.07.09 Wed News Nature Publishing Index - Asia-Pacific (Advertise) 2014.04.23 Wed Admissions “Discovery of the molecule Sox17 to maintain the hematopoietic stem cell at embryonic stages” 2014.04.02 Wed News Vol 6 of our public relations magazine 'TMDU ANNUAL NEWS' issued 2010.02.26 Fri Topics
2020.09.23 Wed Admissions Frosted branch angiitis after allogeneic haematopoietic stem cell transplantation in adult T-cell leukaemia-lymphoma
2020.09.11 Fri Admissions Age-dependent and seasonal changes in menstrual cycle length and body temperature based on big data
2020.07.27 Mon Admissions Targeting all transforming growth factor-β isoforms with an Fc chimeric receptor impairs tumor growth and angiogenesis of oral squamous cell cancer
2020.07.14 Tue Admissions Shigella prevents infected cells from sacrificing themselves for the greater good
2020.06.02 Tue Admissions In vitro neo-genesis of tendon-like tissue by combination of Mohawk and a three-dimensional cyclic mechanical stretch culture system
2020.06.01 Mon Admissions “Opening of an open-laboratory for research into next generation ventilators, and for evaluation and research, etc. of new ventilator types, with a view towards responding to the surge in numbers of novel coronavirus patients”
2020.06.01 Mon Admissions Lin28a/let-7 Pathway Modulates the Hox Code via Polycomb Regulation during Axial Patterning in Vertebrates
2020.05.25 Mon Admissions Characterization of radioresistant epithelial stem cell heterogeneity in the damaged mouse intestine
2020.02.12 Wed Admissions A Joint Clinical Research Collaboration among Tokyo Medical and Dental University (TMDU), ACT Genomics , and ACTmed Seeks to Investigate the Cancer Genomic Landscape of Japanese Population
2020.01.28 Tue Admissions All screen print Text print YAP-dependent necrosis occurs in early stages of Alzheimer's disease and regulates mouse model pathology
2020.01.15 Wed News A Novel, Tumor-Induced Osteoclastogenesis Pathway In sensitive to Denosumab but Interfered by Cannabidiol
2020.01.08 Wed News Vpu of a Simian Immunodeficiency Virus Isolated from Greater Spot-Nosed Monkey Antagonizes Human BST-2 via Two AxxxxxxxW Motifs
2019.12.25 Wed Admissions Transcutaneous blood VOC imaging system (skin-gas cam) with real-time bio-fluorometric device on rounded skin surface
2019.12.25 Wed News Transcutaneous blood VOC imaging system (skin-gas cam) with real-time bio-fluorometric device on rounded skin surface
2019.12.23 Mon News Intracellular claudin‐1 at the invasive front of tongue squamous cell carcinoma is associated with lymph node metastasis
2019.11.27 Wed News Temporospatial sonic hedgehog signalling is essential for neural crest-dependent patterning of the intrinsic tongue musculature
2019.11.07 Thu News 18th Surugadai International Symposium & Joint Usage/Research Program of Medical Research Institute International Symposium(2019.11.18)
2019.11.06 Wed Admissions Bile duct biomarker? Protein found to pinpoint patients with a lethal cancer
2019.11.01 Fri News A Nice Reactive Ring to It: New Synthetic Pathways for Diverse Aromatic Compounds
2019.10.21 Mon Admissions “Instant Liver, Just Add Water”? Not Quite, but a Better Way to Grow Multiple Organs
2019.09.24 Tue News Comparative analysis demonstrates cell type-specific conservation of SOX9 targets between mouse and chicken
2019.07.30 Tue News Involvement of N-type Ca2+ channel in microglial activation and its implications to aging-induced exaggerated cytokine response
2019.07.24 Wed News "HDO-antimiR represents a new weapon in the fight against microRNA-related disease"
2019.07.04 Thu Admissions Enhancement of Motor Function Recovery After Spinal Cord Injury in Mice by Delivery of Brain Derived Neurotrophic Factor mRNA
2019.07.03 Wed Admissions Fibroblast growth factor signals regulate transforming growth factor‐β‐induced endothelial‐to‐myofibroblast transition of tumor endothelial cells via Elk1
2019.07.01 Mon News Tolvaptan activates the Nrf2/HO-1 antioxidant pathway through PERK phosphorylation
2019.06.25 Tue News Blockade of microglial Cav1.2 Ca2+ channel exacerbates the symptoms in a Parkinson’s disease model
2019.06.13 Thu News Reciprocal cortical activation patterns during incisal and molar biting correlated with bite force levels: an fMRI study.
2019.06.07 Fri News Nature Medicine is focusing on Prof.Takanori Takebe (Organ and Tissue Neogenesis Consortium, Institute of Research) .
2019.06.07 Fri News A Review Article, “Organoid by Design”, by Prof.Takanori Takebe (Organ and Tissue Neogenesis Consortium, Institute of Research) has been published on Science.
2019.06.05 Wed News MRTF A regulates proliferation and survival properties of pro atherogenic macrophages
2019.05.29 Wed News Antibacterial activity of lysozyme-chitosan oligosaccharide conjugates (LYZOX) against Pseudomonas aeruginosa, Acinetobacter baumannii and Methicillin-resistant Staphylococcus aureus
2019.04.23 Tue News Synthesis of Alkynyl Sulfides by Copper-Catalyzed Thiolation of Terminal Alkynes Using Thiosulfonates
2019.04.16 Tue News Silencing of PD-L2/B7-DC by Topical Application of Small Interfering RNA Inhibits Elicitation of Contact Hypersensitivity
2019.04.16 Tue Admissions Silencing of PD-L2/B7-DC by Topical Application of Small Interfering RNA Inhibits Elicitation of Contact Hypersensitivity
2019.04.10 Wed News Impact of novel NS5A resistance-associated substitutions of hepatitis C virus detected in treatment-experienced patients
2019.03.11 Mon News TMDU is ranked 1st (Dentistry in Japan) and 3rd (Medicine in Japan) in QS World University Rankings 2019 by Subject!
2019.01.18 Fri News "The clock components Period2, Cryptochrome1a, and Cryptochrome2a function in establishing light-dependent behavioral rhythms and/or total activity levels in zebrafish"
2017.12.27 Wed News "Alzheimer’s Disease Pathway Identification Enables Development of Novel Preclinical Therapy"
2017.07.14 Fri News "Reduced mastication results in the impairment of memory and learning function"
2017.07.14 Fri Admissions The 562th Medical Research Institute Seminar, The 135th Joint Usage/Research Program of Medical Research Institute Seminar「Epilepsies linked to mTOR1 pathway」
2017.06.13 Tue Admissions "Discovery of Human Blood Cell Destinies Revises Knowledge of Immune Cell Development"
2017.05.09 Tue News International Conference for Precision Cancer Medicine 2017 (Thu 29 Jun - Fri 30 Jun 2017)
2017.03.30 Thu Admissions "Differences in Microbial Interactions Underlie Related Oral Diseases"
2017.03.30 Thu Admissions "Method Identified to Boost Detection of Highly Cancerous Stem Cells"
2017.03.28 Tue News Vol.2 of our New publication specialized in our research activities TMDU Research Activities 2017 issued
2017.01.17 Tue News "Metabolic Pathway Regulating Key Stage of Embryo Development Revealed"
2016.12.27 Tue Admissions "All screen print Text print "Alzheimer’s Disease Pathway Identification Enables Development of Novel Preclinical Therapy"
2016.12.16 Fri Admissions "Degrader of Proteins Required for the Origin of Early Cancerous Lesions"
2016.12.14 Wed Admissions "Breakthrough in Hepatitis Research as New Infected Cell Models are Developed"
2016.11.24 Thu Admissions "Novel Method of Cellular Waste Disposal Revealed in Yeast and Mammals"
2016.11.24 Thu Admissions ”Role for Autophagic Cellular Degradation Process in Maintaining Genomic Stability”
2016.11.22 Tue Admissions ”Novel Type of Cell Death in Huntington’s Disease May Lead to Effective New Therapies”
2016.11.22 Tue News "How Cell Populations Weed Out “Loser” Cells to Maintain Vitality is Revealed"
2016.11.01 Tue News "Advancing Our Understanding of How the Disease Lupus is prevented in healthy individuals"
2016.10.05 Wed Admissions “Breakthrough for Bone Regeneration via Double-cell-layered Tissue Engineering Technique”
2016.06.07 Tue Admissions “World's First Measurement and Visualization of Cardiac Activity Using MR Sensors”
2016.03.30 Wed News Vol 1 of our New publication specialized in our research activities 'TMDU Research Activities 2016' issued
2016.02.16 Tue Admissions “Periodic injections of synovial stem cells inhibit osteoarthritis progression in the knee”
2016.02.01 Mon Admissions “Synthetic polymer-based elucidation of survival strategies of cancer stem cells”
2015.09.29 Tue Admissions Tokyo Medical and Dental University to establish an INCJ-backed venture company, Rena Therapeutics Inc.
2015.05.12 Tue News TMDU ranked #1 in the Nation and #6 in the World in Dentistry by QS World University Rankings
2014.07.09 Wed News The Program for Promoting the Enhancement of Research Universities ( from TMDU Annual News )
2014.04.23 Wed Admissions “Discovery of the molecule Sox17 to maintain the hematopoietic stem cell at embryonic stages”