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| 2006-2010 | 2001-2005 | |||
| 1996-2000 | 1991-1995 | ‘à (‰p•¶ / ˜a•¶) | ||
| [2006-2010] |
| Modulation of intramolecular heterodimer-induced fluorescence quenching of tricarbocyanine dye for the development of fluorescent sensors. Hirano, T.; Akiyama, J.; Mori, S.; Kagechika, H. Org. Biomol. Chem. 2010, 8, 5568-5575 |
| Design and Synthesis of Novel Retinoid Synergists having a Dibenzodiazepine Skeleton. Ohta, K.; Kawachi, E.; Shudo, K.; Kagechika, H. Heterocycles 2010, 81, 2465-2470 |
| Development of novel bisubstrate-type inhibitors of histone methyltransferase SET7/9. Mori, S.; Iwase, K.; Iwanami, N.; Tanaka, Y.; Kagechika, H.; Hirano, T. Bioorg. Med. Chem. 2010, 18, 8158-8168 |
| Efficient Induction of CCR9 on T Cells Requires Coactivation of Retinoic Acid Receptors and Retinoid X Receptors (RXRs): Exaggerated T Cell Homing to the Intestine by RXR Activation with Organotins. Takeuchi, H.; Yokota, A.; Ohoka, Y.; Kagechika, H.; kato, C.; Song, S.-Y.; Iwata, M. J. Immunol. 2010, 185, 5289-5299 |
| Cyclic-tri(N-methyl-meta-benzamide)s: substituent effects on the bowl- shaped conformation in the crystal and solution states. Kakuta, H.; Azumaya, I.; Masu, H.; Matsumura, M.; Yamaguchi, K.; Kagechika, H.; Tanatani, A. Tetrahedron 2010, 66, 8254-8260 |
| Retinoic Acid Induces Expression of the Thyroid Hormone Transporter, Monocarboxylate Transporter 8 (Mct8). Kogai, T.; Liu, Y.-Y.; Richter, L. L.; Mody, K.; Kagechika, H.; Bent, G. A. J. Biol. Chem. 2010, 285, 27279-27288 |
| In Vitro Murine Spermatogenesis in an Organ Culture System. Gohbara, A.; Katagiri, K.; Sato, T.; Kubota, Y.; Kagechika, H.; Araki, Y.; Araki, Y.; Ogawa, T. Biol. Reprod. 2010, 83, 262-267 |
| Latent Enamine Functionality of 5-Methyl-2,3-dihydropyradines. Ito, S.; Hirano, T.; Sugimoto, A.; Kagechika, H.; Takeuchi, S.; Yamaguchi, T. Chem. Pharm. Bull. 2010, 58, 885-1002 |
| Inhibition of Mammary Carcinoma Cell Growth by RXR is Mediated by the Receptor's Oligomeric Switch. Yasmin, R.; Kannan-Thulasiraman, P.; Kagechika, H.; Dawson, M. I.; Noy, N. J. Mol. Biol. 2010, , 397 1121-1131 |
| Enhancement of imatinib-induced apoptosis of BCR/ABL-expressing cells by nutlin-3 through synergistic activation of the mitochondrial apoptoic pathway. Kurosu, T.; Wu, N.; Oshikawa, G.; Kagechika, H.; Miura, O. Apoptosis 2010, 15, 608-620 |
| Activation of Testicular Orphan Receptor 4 by Fatty Acids. Tsai, N.-P.; Huq, M.; Gupta, P.; Yamamoto, K.; Kagechika, H.; Wei, L.-N. Biochim. Biophys. Acta- Gene Regul. Mech. 2009, 1789 734-740 |
| Identification of Absolute Helical Structures of Aromatic Multi-layered Oligo(m-phenylurea)s in solution Kudo, M.; Hanashima, T.; Muranaka, A.; Sato, H.; Uchiyama, M.; Azumaya, I.; Hirano, T.; Kagechika, H.; Tanatani, A. J. Org. Chem. 2009, 74 8154-8163 |
| Hypoxia-Inducible Factor-3ƒ¿ Functions as an Accelerator of 3T3-L1 Adipose Differentiation. Hatanaka, M.; Shimba, S.; Sakaue, M.; Kondo, Y.; Kagechika, H.; Kokame, K.; Miyata, T.; Hara, S. Biol. Pharm. Bull. 2009, 32 1166-1172 |
| Docosahexaenoic acid induces adipose differentiation-related protein through activation of retinoid X receptor in human choriocarcinoma BeWo cells. Suzuki, K.; Takahashi, K.; Nishinaki-Mogami, T.; Kagechika, H.; Yamamoto, M.; Itabe, H. Biol. Pharm. Bull. 2009, 32 1177-1182 |
| Encapsulation of the synthetic retinoids Am80 and LE540 into polymeric micelles and the retinoids' rerease control. Satoh, T.; Higuchi, Y.; Kawakami, S.; Hashida, M.; Kagechika, H.; Shudo, K.; Yokoyama, M. J. Controlled Release 2009, 136 187-195 |
| Sorafenib induces apoptosis specifically in cells expressing BCR/ABL by inhibiting its kinase activity to activate the intrinsic mitochondrial pathway. Kurosu, T.; Ohki, M.; Wu, N.; Kagechika, H.; Miura, O. Cancer Res. 2009, 69 3927-3936 |
| Activation of the PI3 Kinase Pathway By Retinoic Acid Mediates Sodium/Iodide Symporter Induction and Iodide Transport in MCF-7 Breast Cancer Cells. Ohashi, E.; Kogai, T.; Kagechika, H.; Brent, G. A. Cancer Res. 2009, 69 3443-3450 |
| The transcriotion factors Nur77 and retinoid X receptors participate in amphetamine-induced locomotor activities. Bourhis, E.; Maheux, J.; Paquet, B.; Kagechika, H.; Shudo, K.; Rompr?, P.; Rouillard, C.; L?vesque, D. Psychopharmacol., 2009, 202, 635-648. |
| ApoC-III gene expression is sharply increased during adipogenesis and is augmented by retinoid X receptor (RXR) agonists. Takahashi, Y.; Inoue, J.; Kagechika, H.; Sato, R. FEBS Lett. 2009, 583, 493-497. |
| Contribution of AP-1 interference induced by TAC-101 to tumor growth suppression in a hepatocellular carcinoma model.
Eshima, K.; Fukaya S.; Sugimoto, A.; Mori, T.; Yokoi, H.; Yamamoto, Y.; Sugiura, S.; Honda, S.; Masuko, N.; Murakami, K.; Yamasaki, Y.; Kagechika, H. Tumor Biol. 2009, 30, 1-7. |
| Fluorescent visualization of the conformational change of aromatic amide or urea induced by N-methylation.
Hirano, T.; Osaki, T.; Fujii, S.; Komatsu, D.; Azumaya, I.; Tanatani, A.; Kagachika, H. Tetrahedron Lett. 2009, 50, 488-491. |
| Acidic heterocycles as novel hydrophilic pharmacophore of androgen receptor ligands with a carborane core structure.
Fujii, S.; Ohta, K.; Goto, T.; Kagechika, H.; Endo, Y. Bioorg. Med. Chem. 2009, 17, 344-350. |
| The RXR agonists PA024 and HX630 have different abilities to activate LXR/RXR and to induce ABCA1 expression in macrophage cell line. Nishimaki-Mogami, T.; Tamehiro, N.; Sato, Y.; Okuhira, K.; Sai, K.; Kagechika, H.; Shudo, K.; Abe-Dohmae, S.; Yokoyama, S.; Ohno, Y.; Inoue, K.; Sawada, J. Biochem. Pharmacol. 2008, 76, 1006-1013. |
| Polymorphism and Pseudopolymorphism of an Aromatic Amide: Spontaneous Resolution and Crystal-to-Crystal Phase Transition.
Kato, T.; Okamoto, I.; Masu, H.; Katagiri, K.; Tominaga, M.; Yamaguchi, K.; Kagechika, H.; Azumaya, I. Cryst. Growth Des. 2008, 8, 3871-3877. |
| Effects of retinoic acids on the dendritic morphology of cultured hippocampal meurons.
Liu, Y.; Kagechika, H.; Ishikawa, J.; Hirano, H.; Matsukuma, S.; Tanaka, K.; Nakamura, S. J. Neurochem. 2008, 106, 1104-1116. |
| Chiral Spherical Molecules Constructed from Aromatic Amides: Facile Synthesis and Highly Ordered Network Structure in the Crystal.
Masu, H.; Katagiri, K.; Kato, T.; Kagechika, H.; Tominaga, M.; Azumaya, I. J Org. Chem. 2008, 73, 5143-5146. |
| Identification of An
Intermediate in the Deboronation of ortho-Carborane: An Adduct of
ortho-Carborane with Two Nucleophiles on One Boron Atom.
Taoda, Y.; Sawabe, T.; Endo, Y. Yamaguchi, K.; Fujii, S.; Kagechika, H. Chem. Commun. 2008, 2049-2051. |
| 13-cis-Retinoic acid alters the
cellular morphology of slice-cultured serotonergic neurons in the
rat. Ishikawa, J.; Sutoh, C.; Ishikawa, A.; Kagechika, H.; Hirano, H.; Nakamura, S. Eur. J. Neurosci. 2008, 27, 2363-2372. |
| Redox-Induced Conformational
Alteration of N,N-Diarylamides. Okamoto, I.; Yamasaki, R.; Sawamura, M.; Kato, T.; Nagayama, N.; Takeya, T.; Tamura, O.; Masu, H.; Azumaya, I.; Yamaguchi, K.; Kagechika, H.; Tanatani, A. Org. Lett. 2007, 9, 5545-5547. |
| ƒÀ-Cryptoxanthin, a novel
natural RAR ligand, induces ATP-binding cassette transporters in
macrophages. Matsumoto, A.; Mizukami, H.; Mizuno, S.; Umegaki, K.; Nishikawa, J.; Shudo, K.; Kagechika, H.; Inoue, M.; Biochem. Pharmacol. 2007, 74, 256-264. 2007. |
| STAT5ƒ¿/PPARƒÁ Pathway Regulates
Involucrin Expression in Keratinocyte Differentiation. Dai, X.; Sayama, K.; Shirakata, Y.; Hanakawa, Y.; Yamasaki, K.; Tokumaru, S.; Yang, L.; Wang, X.; Hirakawa, S.; Tohyama, M.; Yamauchi, T.; Kadowaki, T.; Kagechika, H.; Hashimoto, K.; J. Invest. Dermatol. 2007, 127, 1728-1735. |
| Novel Thyroid Hormone Receptor
Antagonists With An N-Alkylated Diphenylamine
Skeleton. Komatsu, T.; Hirano, T.; Songkram, C.; Kawachi, E.; Kagechika, H.; Bioorg. Med. Chem. 2007, 15, 3115-3126. |
| All-trans
Development of a Library of 6-Arylcoumarins as Candidate Fluorescent
Sensors. Hirano, T.; Hiromoto, K.; Kagechika, H.; Organic Lett. 2007, 9, 1315-1318. |
| All-trans
Retinoic Acid Induces In Vitro Angiogenesis via Retinoic Acid Receptor:
Possible Involvement of Paracrine Effects of Endogenous Vascular
Endothelial Growth Factor Signaling Saito, A.; Sugawara, A.; Uruno, A.; Kudo, M.; Kagechika, H.; Sato, Y.; Owada, Y.; Kondo, H.; Sato, M.; Kurabayashi, M.; Imaizumi, M.; Tsuchiya, S.; Ito, S. Endocrinology 2007, 148, 1412-1423. |
| Construction of
anomalously bent biphenyl structure using conformational properties of
calix[4]amide Tominaga, M.; Hatano, T.; Uchiyama, M.; Masu, H.; Kagechika, H.; Azumaya, I. Teterahedron Lett. 2006, 47, 9369-9371. |
| A New RXR Agonist, HX630,
suppresses intimal hyperplasia in a mouse blood flow cessation
model Haraguchi, G.; Suzuki, J.; Kosuge, H.; Ogawa, M.; Koga, N.; Muto, S.; Itai, A.; Kagechika, H.; Shudo, K.; Isobe, M. J. Mol. Cell. Cardiol. 2006, 41, 885-892. |
| Spontaneous
Resolution of Aromatic Sulfonamides: Effective Screening Method and
Discrimination of Absolute Structure Kato, T.; Okamoto, I.; Tanatani, A.; Hatano, T.; Uchiyama, M.; Kagechika, H.; Masu, H.; Katagiri, K.; Tominaga, M.; Yamaguchi, K.; Azumaya, I. Org. Lett. 2006, 8, 5017-5020. |
| Retinoids Induce Growth
Inhibition and Apoptosis in Mast Cell Tumor Cell
Lines Ohashi , E.; Miyajima, N.; Nakagawa, T.; Takahashi, T.; Kagechika, H.; Mochizuki, M.; Nishimura, R.; Sasaki, N. J. Vet. Med. Sci. 2006, 68, 797-802. |
| Solvent-Dependent
Conformational Switching of N-Phenylhydroxamic Acid and Its Application in
Crystal Engineering Yamasaki, R.; Tanatani, A.; Azumaya, I.; Masu, H.; Yamaguchi, K.; Kagechika, H. Crystal Growth Des. 2006, 6, 2007-2010. |
| Genetic and pharmacological
evidence that a retinoic acid cannot be the RXR-activating ligand in mouse
epidermis keratinocytes Calleja, C.; Messaddeq, N.; Chapellier, B.; Yang, H.; Krezel, W.; Li, M.; Metzger, D.; Mascrez, B.; Ohta, K.; Kagechika, H.; Endo, Y.; Mark, M.; Ghyselinck, N. B.; Chambon, P. Genes Develop. 2006, 20, 1525-1538. |
| The synthetic retinoid Am80
reduces scavenger receptor expression and atherosclrosis in mice by
inhibiting IL-6. Takeda, N.; Manabe, I.; Shindo, T.; Iwata, H.; Iimuro, S.; Kagechika, H.; Shudo, K.; Nagai, R. Arterioscl. Thromb. Vas., 2006, 26, 1177-1183. |
| PPARƒÁ ligands stimulate myeloid
differentiation and lipogenensis in the human leukemia NB4
cells. Yasugi, E.; Horiuchi, A.; Uemura, I.; Okuma, E.; Nakatsu, M.; Saeki, K.; Kamisaka, Y.; Kagechika, H.; Yasuda, K.; Yuo, A. Dev. Growth Differ., 2006, 48, 177-188. |
| Calix[3]amides|bowl-shaped cyclic trimers toward building block for
molecular recognition: self-complementary dimeric structure in the
crystal Imabeppu, F.; Katagiri, K.; Masu, H.; Kato, T.; Tominaga, M.; Therrien, B.; Takayanagi, H.; Kaji, E.; Yamaguchi, K.; Kagechika, H.; Azumaya, I. Tetrahedron Lett. 2006, 47, 413-416. |