Ishino Laboratory
Department of Epigenetics, Medical Research Institute, Tokyo Medical and Dental University
Yushima, Bunkyo-ku, Tokyo 113-8510 JAPAN
tel/fax: +81-3-5803-4863
(M & D tower 23th floor
map)
Publications
Lee J, Matsuzawa A, Shiura H, Sutani A and Ishino F.
Changes in DNA methylation imprinting and in vivo stem cell activity caused by in vitro environments.
Genes to Cells 23, 146-160, 2018
Kitazawa M, Tamura M, Kaneko-Ishino T and Ishino F.
Severe damage to the placental fetal capillary network causes mid to late fetal lethality and reduction of placental size in Peg11/Rtl1 KO mice.
Genes Cells 22(2), 174-188 (2017). doi: 10.1111/gtc.12465
Wakayama S, Kamada Y, Yamanaka K, Kohda T, Suzuki H, Shimazu T, Motoki, N. Tada M N, Osada I, Nagamatsu A, Kamimura S, Nagatomo H, Mizutani E, Ishino F, Yano S, Wakayama T.
Healthy offspring from freeze-dried mouse spermatozoa held on the International Space Station for 9 months. P
roc Natl Acad Sci USA 114(23):5988-5993 2017). doi: 10.1073/pnas.1701425114
Kaneko-Ishino T, Irie M and Ishino F.
Mammalian-specific traits generated by LTR retrotransposon-derived SIRH genes.
In Evolutionary Biology: Self/NonSelf Evolution, Species and Complex Traits Evolution, Methods and Concepts (ed. Pontarotti P), Springer International Publishing, pp.129-145 (2017). doi: 10.1007/978-3-19-61569-1_7
Kawasaki Y, Kuroda Y, Suetake I, Tajima S, Ishino F and Kohda T.
A novel method for the simultaneous identification of methylcytosine and hydroxymethylcytosine at a single base resolution.
Nucl Acids Res 45(4):e24 (2017). doi: 10.1093/nar/gkw994
Kobayashi S, Hosoi Y, Shiura H, Yamagata K, Takahashi S, Fujihara Y, Kohda T, Okabe M and Ishino F.
Live imaging of X chromosome reactivation dynamics in early mouse development can discriminate na?ve from primed pluripotent stem cells.
Development 143(16), 2958-2964 (2016). doi: 10.1242/dev.136739.
Irie M, Koga A, Kaneko-Ishino T and Ishino F.
An LTR retrotransposon-derived gene displays lineage-specific structural and putative species-specific functional variations in eutherians.
Front Chem 4:26.(2016) doi: 10.3389/fchem.2016.00026.
Kaneko-Ishino T and Ishino F.
Mammalian-specific genomic functions: Newly acquired traits generated by genomic imprinting and LTR retrotransposon-derived genes in mammals.
Proc Jpn Acad Ser B Phys Biol Sci. 2015;91(10):511-538(2015). doi: 10.2183/pjab.91.511.
Irie M, Yoshikawa M, Ono R, Iwafune H, Furuse T, Yamada I, Wakana S, Yamashita Y, Abe T, Ishino F and Kaneko-Ishino T.
Cognitive function related to the Sirh11/Zcchc16 gene acquired from an LTR retrotransposon in eutherians.
PLoS Genet 11(9):e1005521 (2015). doi: 10.1371/journal.pgen.1005521.
Ono R, Ishii M, Fujihara Y, Kitazawa M, Usami T, Kaneko-Ishino T, Kanno J, Ikawa M and Ishino F.
Double strand break repair by capture of retrotransposon sequences and reverse-transcribed spliced mRNA sequences in mouse zygotes.
Sci Rep. 5:12281 (2015). doi: 10.1038/srep12281.
Ito M, Sferruzzi-Perri A N, Edwards C A, Adalsteinsson B T, Allen S E, Loo T-H, Kitazawa M, Kaneko-Ishino T, Ishino F, Stewart C L and Ferguson-Smith A C.
A trans-homologue interaction between reciprocally imprinted miR-127 and Rtl1 regulates placenta development.
Development 142(14), 2425-2430 (2015). doi: 10.1242/dev.121996.
Kagami M, Kurosawa K, Miyazaki O, Ishino F, Matsuoka K, Ogata T.
Comprehensive clinical studies in 34 patients with molecularly defined UPD(14)pat and related conditions (Kagami-Ogata syndrome).
Eur J Hum Genet 23(11), 1488-1498 (2015). doi: 10.1038/ejhg.2015.13.
Naruse M, Ono R, Irie M, Nakamura K, Furuse T, Hino T, Oda K, Kashimura M, Yamada I, Wakana S, Yokoyama M, Ishino F, Kaneko-Ishino T.
Sirh7/Ldoc1 knockout mice exhibit placental P4 overproduction and delayed parturition.
Development 141(24), 4763-4771 (2014). doi: 10.1242/dev.114520.
Takahashi S, Lee J, Kohda T, Matsuzawa A, Kawasumi M, Kanai-Azuma M, Kaneko-Ishino T and Ishino F.
Induction of the G2/M transition stabilizes haploid embryonic stem cells.
Development 141(20), 3842-3847 (2014). doi: 10.1242/dev.110726. Epub 2014 Sep 24.
Kamimura, S., Hatanaka, Y., Hirasawa, R., Matsumoto, K., Oikawa, M., Lee, J., Matoba, S., Mizutani, E., Ogonuki, N., Inoue, K., Kohda, T., Ishino, F. and Ogura, A.
Establishment of paternal genomic imprinting in mouse prospermatogonia analyzed by nuclear transfer.
Biol Reprod 91(5):120 (2014). DOI:10.1095/biolreprod.114.120451
Soma, M., Fujihara, Y., Okabe, M., Ishino, F. and Kobayashi, S.
Ftx is dispensable for imprinted X-chromosome inactivation in preimplantation mouse embryos.
Sci Rep. 4:5181 (2014). doi: 10.1038/srep05181.
Oikawa, M., Inoue, K., Shiura, H., Matoba, S., Kamimura, S., Hirose, M., Mekada, K., Yoshiki, A., Tanaka, S., Abe, K., Ishino, F. and Ogura, A.
Understanding the X chromosome inactivation cycle in mice: A comprehensive view provided by nuclear transfer.
Epigenetics. 9(2), 1-8 (2014). doi:10.4161/epi.26939. February, PMID: 24172050
Kawasaki, Y., Lee, J., Matsuzawa, A., Kohda, T., Kaneko-Ishino, T. and Ishino F.
Active DNA demethylation is required for complete imprint erasure in primordial germ cells.
Sci Rep 4:3658 (2014). January 13, doi: 10.1038/srep03658. PMID: 24413819
Lee, J., Kohda, T. and Ishino, F.
Nuclear transfer with germ cells -Germ cell cloning contributes to current understanding of genomic imprinting in mammals- In Principles of Cloning 2nd Edition (eds. Cibelli, J et al.),
Chapter 5, Elsevier, pp.53-62 (2013)
Kaneko-Ishino, T. and Ishino, F.
The evolution of the placenta and viviparity is related to LTR genomic retrotransposon-derived genes in mammals.
J Mamm Ova Res, 30(1) 16-23 (2013). 4月号
Kobayashi S, Totoki Y, Soma M, Matsumoto K, Fujihara Y, Toyoda A, Sakaki Y, Okabe M, Ishino F.
Identification of an imprinted gene cluster in the x-inactivation center.
PLoS One. 2013 Aug 6;8(8):e71222.
Nishimoto M, Katano M, Yamagishi T, Hishida T, Kamon M, Suzuki A, Hirasaki M, Nabeshima Y, Nabeshima Y, Katsura Y, Satta Y, Deakin JE, Graves JA, Kuroki Y, Ono R, Ishino F, Ema M, Takahashi S, Kato H, Okuda A.
In vivo function and evolution of the eutherian-specific pluripotency marker UTF1.
PLoS One. 2013 Jul 9;8(7):e68119.
Iwasaki S, Suzuki S, Pelekanos M, Clark H, Ono R, Shaw G, Renfree MB, Kaneko-Ishino T, Ishino F.
Identification of a Novel PNMA-MS1 Gene in Marsupials Suggests the LTR retrotransposon-derived PNMA Genes Evolved Differently in Marsupials and Eutherians.
DNA Res. 2013 May 23. [Epub ahead of print]
Wakayama S, Kohda T, Obokata H, Tokoro M, Li C, Terashita Y, Mizutani E, Nguyen VT, Kishigami S, Ishino F, Wakayama T.
Successful serial recloning in the mouse over multiple generations.
Cell Stem Cell. 2013 Mar 7;12(3):293-7.
Oikawa M, Matoba S, Inoue K, Kamimura S, Hirose M, Ogonuki N, Shiura H, Sugimoto M, Abe K, Ishino F, Ogura A.
RNAi-mediated knockdown of Xist does not rescue the impaired development of female cloned mouse embryos.
J Reprod Dev. 2013;59(3):231-7.
Ishino F, Shinkai Y, Whitelaw E.
Mammalian epigenetics in biology and medicine.
Philos Trans R Soc Lond B Biol Sci. 2013 Jan 5;368(1609):20120386.
Kohda T, Ishino F.
Embryo manipulation via assisted reproductive technology and epigenetic asymmetry in mammalian early development.
Philos Trans R Soc Lond B Biol Sci. 2013 Jan 5;368(1609):20120353.
Kohda T, Kishigami S, Kaneko-Ishino T, Wakayama T, Ishino F.
Gene expression profile normalization in cloned mice by trichostatin A treatment.
Cell Reprogram. 2012 Feb;14(1):45-55.
Kaneko-Ishino, T. and Ishino, F.
The role of genes domesticated from LTR retrotransposons and retroviruses in mammals.
Frontiers Microbiol 2012, 3, Article 262 (1-10).
Matoba S, Inoue K, Kohda T, Sugimoto M, Mizutani E, Ogonuki N, Nakamura T, Abe K, Nakano T, Ishino F, Ogura A.
RNAi-mediated knockdown of Xist can rescue the impaired postimplantation development of cloned mouse embryos.
Proc Natl Acad Sci U S A. 2011 Dec 20;108(51):20621-6.
Suzuki S, Shaw G, Kaneko-Ishino T, Ishino F, Renfree MB.
The evolution of mammalian genomic imprinting was accompanied by the acquisition of novel CpG islands.
Genome Biol Evol. 2011;3:1276-83.
Suzuki S, Shaw G, Kaneko-Ishino T, Ishino F, Renfree MB.
Characterisation of marsupial PHLDA2 reveals eutherian specific acquisition of imprinting.
BMC Evol Biol. 2011 Aug 19;11:244.
Kohda T, Ogonuki N, Inoue K, Furuse T, Kaneda H, Suzuki T, Kaneko-Ishino T, Wakayama T, Wakana S, Ogura A, Ishino F.
Intracytoplasmic sperm injection induces transcriptome perturbation without any transgenerational effect.
Biochem Biophys Res Commun. 2011 Jul 1;410(2):282-8.
Ono R, Kuroki Y, Naruse M, Ishii M, Iwasaki S, Toyoda A, Fujiyama A, Shaw G, Renfree MB, Kaneko-Ishino T, Ishino F.
Identification of tammar wallaby SIRH12, derived from a marsupial-specific retrotransposition event.
DNA Res. 2011 Aug;18(4):211-9.
Inoue K, Kohda T, Sugimoto M, Sado T, Ogonuki N, Matoba S, Shiura H, Ikeda R, Mochida K, Fujii T, Sawai K, Otte AP, Tian XC, Yang X, Ishino F, Abe K, Ogura A.
Impeding Xist expression from the active X chromosome improves mouse somatic cell nuclear transfer.
Science. 2010 Oct 22;330(6003):496-9.
Kaneko-Ishino T, Ishino F.
Retrotransposon silencing by DNA methylation contributed to the evolution of placentation and genomic imprinting in mammals.
Dev Growth Differ. 2010 Aug;52(6):533-43.
Kobayashi S, Fujihara Y, Mise N, Kaseda K, Abe K, Ishino F, Okabe M.
The X-linked imprinted gene family Fthl17 shows predominantly female expression following the two-cell stage in mouse embryos.
Nucleic Acids Res. 2010 Jun;38(11):3672-81.
Miki H, Hirose M, Ogonuki N, Inoue K, Kezuka F, Honda A, Mekada K, Hanaki K, Iwafune H, Yoshiki A, Ishino F, Ogura A.
Efficient production of androgenetic embryos by round spermatid injection.
Genesis. 2009 Mar;47(3):155-60.
Kaneko-Ishino T, Ishino F.
Platypus, its unique position in mammals: genome reveals the evolution of mammals.
Tanpakushitsu Kakusan Koso. 2009 Jan;54(1):58-64.
Shiura H, Nakamura K, Hikichi T, Hino T, Oda K, Suzuki-Migishima R, Kohda T, Kaneko-ishino T, Ishino F.
Paternal deletion of Meg1/Grb10 DMR causes maternalization of the Meg1/Grb10 cluster in mouse proximal Chromosome 11 leading to severe pre- and postnatal growth retardation.
Hum Mol Genet. 2009 Apr 15;18(8):1424-38.
Sekita, Y., Wagatsuma, H., Nakamura, K., Ono, R., Kagami, M., Wakisaka, N., Hino, T., Suzuki-Migishima, R., Kohda, T., Ogura, A., Ogata, T., Yokoyama, M., Kaneko-Ishino, T. and Ishino, F.
Role of retrotransposon-derived imprinted gene, Rtl1, in the feto-maternal interface of mouse placenta.
Nat Genet. 2008 Feb;40(2):243-8.
Kagami, M. *, Sekita, Y.*, Nishimura, G., Irie, M., Kato, F., Okada, M., Yamamori, S., Kishimoto, H., Nakayama, M., Tanaka, Y., Matsuoka, K., Takahashi, T., Noguchi, M., Tanaka, Y., Masumoto, K., Utsunomiya, T., Kouzan, H., Komatsu, Y., Ohashi, H., Kurosawa, K., Kosaki, K., Ferguson-Smith, A.C., Ishino, F. and Ogata, T.
(*These authors contributed equally to this work.)
Identification of deletions and epimutations in the human chromosome 14q32.2 imprinted region in individuals with paternal and maternal upd(14)-like phenotypes.
Nat Genet. 2008 Feb;40(2):237-42.
Suzuki S, Ono R, Narita T, Pask AJ, Shaw G, Wang C, Kohda T, Alsop AE, Marshall Graves JA, Kohara Y, Ishino F, Renfree MB, Kaneko-Ishino T.
Retrotransposon Silencing by DNA Methylation Can Drive Mammalian Genomic Imprinting.
PLoS Genet. 2007 Apr 13;3(4)
Kamei Y, Suganami T, Kohda T, Ishino F, Yasuda K, Miura S, Ezaki O, Ogawa Y.
Peg1/Mest in obese adipose tissue is expressed from the paternal allele in an isoform-specific manner.
FEBS Lett. 2007 Jan 9;581(1):91-6.
Kohda T, Ishino F, Ogura A.
Expression of imprinted genes in cloned mice.
Methods Mol Biol. 2006;348:237-46.
Wakisaka-Saito N, Kohda T, Inoue K, Ogonuki N, Miki H, Hikichi T, Mizutani E, Wakayama T, Kaneko-Ishino T, Ogura A, Ishino F.
Chorioallantoic placenta defects in cloned mice.
Biochem Biophys Res Commun. 2006 Oct 13;349(1):106-14.
Anahara R, Yoshida M, Toyama Y, Maekawa M, Kai M, Ishino F, Toshimori K, Mori C.
Estrogen agonists, 17beta-estradiol, bisphenol A, and diethylstilbestrol, decrease cortactin expression in the mouse testis.
Arch Histol Cytol. 2006 Jun;69(2):101-7.
Anahara R, Toyama Y, Maekawa M, Yoshida M, Kai M, Ishino F, Toshimori K, Mori C.
Anti-estrogen ICI 182.780 and anti-androgen flutamide induce tyrosine phosphorylation of cortactin in the ectoplasmic specialization between the Sertoli cell and spermatids in the mouse testis.
Biochem Biophys Res Commun. 2006 Jul 21;346(1):276-80.
Sekita Y, Wagatsuma H, Irie M, Kobayashi S, Kohda T, Matsuda J, Yokoyama M, Ogura A, Schuster-Gossler K, Gossler A, Ishino F, Kaneko-Ishino T.
Aberrant regulation of imprinted gene expression in Gtl2lacZ mice.
Cytogenet Genome Res. 2006;113(1-4):223-9.
Kaneko-Ishino T, Kohda T, Ono R, Ishino F.
Complementation hypothesis: the necessity of a monoallelic gene expression mechanism in mammalian development.
Cytogenet Genome Res. 2006;113(1-4):24-30. Review.
Anahara R, Toyama Y, Maekawa M, Kai M, Ishino F, Toshimori K, Mori C.
Flutamide depresses expression of cortactin in the ectoplasmic specialization between the Sertoli cells and spermatids in the mouse testis.
Food Chem Toxicol. 2006 Jul;44(7):1050-6.
Ono R, Nakamura K, Inoue K, Naruse M, Usami T, Wakisaka-Saito N, Hino T, Suzuki-Migishima R, Ogonuki N, Miki H, Kohda T, Ogura A, Yokoyama M, Kaneko-Ishino T, Ishino F.
Deletion of Peg10, an imprinted gene acquired from a retrotransposon, causes early embryonic lethality.
Nat Genet. 2006 Jan;38(1):101-6.
Kagami M, Nishimura G, Okuyama T, Hayashidani M, Takeuchi T, Tanaka S, Ishino F, Kurosawa K, Ogata T.
Segmental and full paternal isodisomy for chromosome 14 in three patients: narrowing the critical region and implication for the clinical features.
Am J Med Genet A. 2005 Oct 1;138(2):127-32. Review.
Kohda T, Inoue K, Ogonuki N, Miki H, Naruse M, Kaneko-Ishino T, Ogura A, Ishino F.
Variation in gene expression and aberrantly regulated chromosome regions in cloned mice.
Biol Reprod. 2005 Dec;73(6):1302-11.
Kanatsu-Shinohara M, Ogonuki N, Iwano T, Lee J, Kazuki Y, Inoue K, Miki H, Takehashi M, Toyokuni S, Shinkai Y, Oshimura M, Ishino F, Ogura A, Shinohara T.
Genetic and epigenetic properties of mouse male germline stem cells during long-term culture.
Development. 2005 Sep;132(18):4155-63.
Shiura H, Miyoshi N, Konishi A, Wakisaka-Saito N, Suzuki R, Muguruma K, Kohda T, Wakana S, Yokoyama M, Ishino F, Kaneko-Ishino T.
Meg1/Grb10 overexpression causes postnatal growth retardation and insulin resistance via negative modulation of the IGF1R and IR cascades.
Biochem Biophys Res Commun. 2005 Apr 15;329(3):909-16.
Isotani A, Nakanishi T, Kobayashi S, Lee J, Chuma S, Nakatsuji N, Ishino F, Okabe M.
Genomic imprinting of XX spermatogonia and XX oocytes recovered from XX<-->XY chimeric testes.
Proc Natl Acad Sci U S A. 2005 Mar 15;102(11):4039-44.
Miki H, Inoue K, Kohda T, Honda A, Ogonuki N, Yuzuriha M, Mise N, Matsui Y, Baba T, Abe K, Ishino F, Ogura A.
Birth of mice produced by germ cell nuclear transfer.
Genesis. 2005 Feb;41(2):81-6.
Suzuki S, Renfree MB, Pask AJ, Shaw G, Kobayashi S, Kohda T, Kaneko-Ishino T, Ishino F.
Genomic imprinting of IGF2, p57(KIP2) and PEG1/MEST in a marsupial, the tammar wallaby.
Mech Dev. 2005 Feb;122(2):213-22.
Kanatsu-Shinohara M, Inoue K, Lee J, Yoshimoto M, Ogonuki N, Miki H, Baba S, Kato T, Kazuki Y, Toyokuni S, Toyoshima M, Niwa O, Oshimura M, Heike T, Nakahata T, Ishino F, Ogura A, Shinohara T.
Generation of pluripotent stem cells from neonatal mouse testis.
Cell. 2004 Dec 29;119(7):1001-12.
Miki H, Lee J, Inoue K, Ogonuki N, Noguchi Y, Mochida K, Kohda T, Nagashima H, Ishino F, Ogura A.
Microinsemination with first-wave round spermatids from immature male mice.
J Reprod Dev. 2004 Feb;50(1):131-7.
Kai M, Irie M, Okutsu T, Inoue K, Ogonuki N, Miki H, Yokoyama M, Migishima R, Muguruma K, Fujimura H, Kohda T, Ogura A, Kaneko-Ishino T, Ishino F.
The novel dominant mutation Dspd leads to a severe spermiogenesis defect in mice.
Biol Reprod. 2004 Apr;70(4):1213-21.
Kaneko-Ishino T, Kohda T, Ishino F.
The regulation and biological significance of genomic imprinting in mammals.
J Biochem (Tokyo). 2003 Jun;133(6):699-711. Review.
Ishino F, Kuroiwa Y, Miyoshi N, Kobayashi S, Kohda T, Kaneko-Ishino T.
Subtraction-hybridization method for the identification of imprinted genes.
Methods Mol Biol. 2001;181:101-12.
Ono R, Shiura H, Aburatani H, Kohda T, Kaneko-Ishino T, Ishino F.
Identification of a large novel imprinted gene cluster on mouse proximal chromosome 6.
Genome Res. 2003 Jul;13(7):1696-705.
Inoue K, Ogonuki N, Mochida K, Yamamoto Y, Takano K, Kohda T, Ishino F, Ogura A.
Effects of donor cell type and genotype on the efficiency of mouse somatic cell cloning.
Biol Reprod. 2003 Oct;69(4):1394-400.
Kashiwagi A, Meguro M, Hoshiya H, Haruta M, Ishino F, Shibahara T, Oshimura M.
Predominant maternal expression of the mouse Atp10c in hippocampus and olfactory bulb.
J Hum Genet. 2003;48(4):194-8.
Ogura A, Inoue K, Ogonuki N, Lee J, Kohda T, Ishino F.
Phenotypic effects of somatic cell cloning in the mouse.
Cloning Stem Cells. 2002;4(4):397-405. Review.
Hikichi T, Kohda T, Kaneko-Ishino T, Ishino F.
Imprinting regulation of the murine Meg1/Grb10 and human GRB10 genes; roles of brain-specific promoters and mouse-specific CTCF-binding sites.
Nucleic Acids Res. 2003 Mar 1;31(5):1398-406.
Kayashima T, Yamasaki K, Yamada T, Sakai H, Miwa N, Ohta T, Yoshiura K, Matsumoto N, Nakane Y, Kanetake H, Ishino F, Niikawa N, Kishino T.
The novel imprinted carboxypeptidase A4 gene ( CPA4) in the 7q32 imprinting domain.
Hum Genet. 2003 Mar;112(3):220-6.
Hitchins MP, Bentley L, Monk D, Beechey C, Peters J, Kelsey G, Ishino F, Preece MA, Stanier P, Moore GE.
DDC and COBL, flanking the imprinted GRB10 gene on 7p12, are biallelically expressed.
Mamm Genome. 2002 Dec;13(12):686-91.
Higashimoto K, Soejima H, Yatsuki H, Joh K, Uchiyama M, Obata Y, Ono R, Wang Y, Xin Z, Zhu X, Masuko S, Ishino F, Hatada I, Jinno Y, Iwasaka T, Katsuki T, Mukai T.
Characterization and imprinting status of OBPH1/Obph1 gene: implications for an extended imprinting domain in human and mouse.
Genomics. 2002 Dec;80(6):575-84.
Kaneko-Ishino T, Kohda T, Ishino F.
[Epigenetics in cloned mice]
Tanpakushitsu Kakusan Koso. 2002 Oct;47(13):1816-21. Review. Japanese.
Lee J, Inoue K, Ono R, Ogonuki N, Kohda T, Kaneko-Ishino T, Ogura A, Ishino F.
Erasing genomic imprinting memory in mouse clone embryos produced from day 11.5 primordial germ cells.
Development. 2002 Apr;129(8):1807-17.
Inoue K, Kohda T, Lee J, Ogonuki N, Mochida K, Noguchi Y, Tanemura K, Kaneko-Ishino T, Ishino F, Ogura A.
Faithful expression of imprinted genes in cloned mice.
Science. 2002 Jan 11;295(5553):297.
Kobayashi S, Kohda T, Ichikawa H, Ogura A, Ohki M, Kaneko-Ishino T, Ishino F.
Paternal expression of a novel imprinted gene, Peg12/Frat3, in the mouse 7C region homologous to the Prader-Willi syndrome region.
Biochem Biophys Res Commun. 2002 Jan 11;290(1):403-8.
Kobayashi S, Uemura H, Kohda T, Nagai T, Chinen Y, Naritomi K, Kinoshita EI, Ohashi H, Imaizumi K, Tsukahara M, Sugio Y, Tonoki H, Kishino T, Tanaka T, Yamada M, Tsutsumi O, Niikawa N, Kaneko-Ishino T, Ishino F.
No evidence of PEG1/MEST gene mutations in Silver-Russell syndrome patients.
Am J Med Genet. 2001 Dec 1;104(3):225-31.
Ono R, Kobayashi S, Wagatsuma H, Aisaka K, Kohda T, Kaneko-Ishino T, Ishino F.
A retrotransposon-derived gene, PEG10, is a novel imprinted gene located on human chromosome 7q21.
Genomics. 2001 Apr 15;73(2):232-7.
Kohda T, Asai A, Kuroiwa Y, Kobayashi S, Aisaka K, Nagashima G, Yoshida MC, Kondo Y, Kagiyama N, Kirino T, Kaneko-Ishino T, Ishino F.
Tumour suppressor activity of human imprinted gene PEG3 in a glioma cell line.
Genes Cells. 2001 Mar;6(3):237-47.
Kobayashi S, Wagatsuma H, Ono R, Ichikawa H, Yamazaki M, Tashiro H, Aisaka K, Miyoshi N, Kohda T, Ogura A, Ohki M, Kaneko-Ishino T, Ishino F.
Mouse Peg9/Dlk1 and human PEG9/DLK1 are paternally expressed imprinted genes closely located to the maternally expressed imprinted genes: mouse Meg3/Gtl2 and human MEG3.
Genes Cells. 2000 Dec;5(12):1029-37.
Ishino F, Kaneko-Ishino T.
[A novel view from research of genomic imprinting]
Tanpakushitsu Kakusan Koso. 2000 Sep;45(12):1909-19. Review. Japanese.
Ogura A, Inoue K, Ogonuki N, Noguchi A, Takano K, Nagano R, Suzuki O, Lee J, Ishino F, Matsuda J.
Production of male cloned mice from fresh, cultured, and cryopreserved immature Sertoli cells.
Biol Reprod. 2000 Jun;62(6):1579-84.
Miyoshi N, Wagatsuma H, Wakana S, Shiroishi T, Nomura M, Aisaka K, Kohda T, Surani MA, Kaneko-Ishino T, Ishino F.
Identification of an imprinted gene, Meg3/Gtl2 and its human homologue MEG3, first mapped on mouse distal chromosome 12 and human chromosome 14q.
Genes Cells. 2000 Mar;5(3):211-20.
Okutsu T, Kuroiwa Y, Kagitani F, Kai M, Aisaka K, Tsutsumi O, Kaneko Y, Yokomori K, Surani MA, Kohda T, Kaneko-Ishino T, Ishino F.
Expression and imprinting status of human PEG8/IGF2AS, a paternally expressed antisense transcript from the IGF2 locus, in Wilms' tumors.
J Biochem (Tokyo). 2000 Mar;127(3):475-83.
Li LL, Szeto IY, Cattanach BM, Ishino F, Surani MA.
Organization and parent-of-origin-specific methylation of imprinted Peg3 gene on mouse proximal chromosome 7.
Genomics. 2000 Feb 1;63(3):333-40.
Li L, Keverne EB, Aparicio SA, Ishino F, Barton SC, Surani MA.
Regulation of maternal behavior and offspring growth by paternally expressed Peg3.
Science. 1999 Apr 9;284(5412):330-3.
Lefebvre L, Viville S, Barton SC, Ishino F, Keverne EB, Surani MA.
Abnormal maternal behaviour and growth retardation associated with loss of the imprinted gene Mest.
Nat Genet. 1998 Oct;20(2):163-9.
Williamson CM, Beechey CV, Ball ST, Dutton ER, Cattanach BM, Tease C, Ishino F, Peters J.
Localisation of the imprinted gene neuronatin, Nnat, confirms and refines the location of a second imprinting region on mouse chromosome 2.
Cytogenet Cell Genet. 1998;81(1):73-8.
Obata Y, Kaneko-Ishino T, Koide T, Takai Y, Ueda T, Domeki I, Shiroishi T, Ishino F, Kono T.
Disruption of primary imprinting during oocyte growth leads to the modified expression of imprinted genes during embryogenesis.
Development. 1998 Apr;125(8):1553-60.
Miyoshi N, Kuroiwa Y, Kohda T, Shitara H, Yonekawa H, Kawabe T, Hasegawa H, Barton SC, Surani MA, Kaneko-Ishino T, Ishino F.
Identification of the Meg1/Grb10 imprinted gene on mouse proximal chromosome 11, a candidate for the Silver-Russell syndrome gene.
Proc Natl Acad Sci U S A. 1998 Feb 3;95(3):1102-7.
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Peg3 imprinted gene on proximal chromosome 7 encodes for a zinc finger protein.
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Peg1/Mest imprinted gene on chromosome 6 identified by cDNA subtraction hybridization.
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