薬剤部の概要

原著論文

2001年~2024年3月現在(下線部は、現在または報告当時薬剤部所属)

原著論文(英文)

2024年
  • Noda T., Miuzno S., Mogushi K., Hase T., Iida Y., Takeuchi K., Ishiwata Y., Nagata M.: Development of a predictive model for nephrotoxicity during tacrolimus treatment using machine learning methods, Br J Clin Pharmacol, 90(3), 675-683(2024).
2023年
  • Yokoyama K., Yakuo T., Mamada M., Nagata M.: Olanzapine overdose in a two-year-old girl resulting in both high serum and plasma levels, Cureus, 15(8), e43002(2023).
  • Kaneko S., Asahina Y., Nakagawa M., Murakawa M., Miyazaki Y., Asakage T., Fukuda S., Namiki T., Kano Y., Nagata M., Tsuchiya J., Miyoshi M., Kitahata-Kawai F., Nitta S., Itsui Y., Kakinuma S., Okamoto R.: Factors associated with liver injury and prognosis in advanced cancer patients treated with immune checkpoint inhibitors. Hepatol Res., 53(5), 450-459(2023)
  • Okihata R., Michi Y., Sunakawa M., Tagashira Y.:Pharmacist-led multi-faceted intervention in an antimicrobial stewardship programme at a dental university hospital in Japan, J Hosp Infect., 136, 30-37(2023)
  • Yasuda S., Sugano K.,Matsuda Y.,Kako J.,Takagi Y.,Watanabe H.,Kasahara Y.,Goya S.,Kohara H., Mori M., Nakayama T., Yamaguchi T.:Systematic review and meta-analysis of the efficacy of benzodiazepines for dyspnea in patients with cancer, Jpn J Clin Oncol., 53(4), 327-334(2023)
2022年
  • Takagi M., Ogawa C., Iehara T., Aoki-Nogami Y., Ishibashi E., Imai M., Kimura T., Nagata M., Yasuhara M., Masutani M., Yoshimura K., Tomizawa D., Ogawa A., Yonemori K., Morishita A., Miyamoto S., Takita J., Kihara T., Nobori K., Hasebe K., Miya F., Ikeda S., Shioda Y., Matsumoto K., Fujimura J., Mizutani S., Morio T., Hosoi H., Koike R.: First Phase I clinical study of olaparib in pediatric patients with refractory solid tumors, Cancer., 128(15), 2949-2957 (2022)
  • Kawano Y., Obana M., Nagata M., Mano Y., Katsuyama M., Negishi K., Takagi M., Shimada S., Aoyama T.: The antiplatelet effect of mirtazapine is mediated by co-blocking 5-HT2A and α2-adrenergic receptors on platelets: an in vitro human plasma-based study, Eur. J. Pharmacol., 917, 174640 (2022)
  • Xue B., Ishiwata Y., Kawano Y., Takahashi H., Negishi K., Aoyama T., Nagata M.: Paliperidone-induced Acute Hyperglycemia is Caused by Adrenaline Secretion via the Activation of Hypothalamic AMP-activated Protein Kinase, Biol. Pharm. Bull., 45(11), 1669-1677(2022)
2021年
  • Kawasumi K., Kawano Y., Kujirai A., Mano Y., Matsui R., Maeda A., Yamamoto Y., Negishi K., Shimada S., Noguchi K., Yamaguchi M., Nagata M., Aoyama T.: Risk factors associated with unplanned acute care in outpatient chemotherapy with oral anticancer drugs as monotherapy or combination therapy with injectable anticancer drugs. Anticancer Res., 41(11), 5827-5834 (2021)
  • Enomoto A., Mano Y., Kawano Y., Nishikawa T., Aoyama T., Sasaki Y., Nagata M., Takahashi H.: Comparison of the Safety and Effectiveness of Four Direct Oral Anticoagulants in Japanese Patients with Nonvalvular Atrial Fibrillation Using Real-World Data, Biol. Pharm. Bull., 44(9), 1294-1302 (2021)
  • Ishiwata Y., Nagata M., Kiuchi S., Ippongi C., Takeda H., Takahashi H.: Intravenous infusion of fentanyl has no effect on blood concentration of tacrolimus in patients receiving hematopoietic stem cell transplantation, Ther. Drug Monit., 43(5), 688-691 (2021)
  • Asada M., Nagata M., Mizuno T., Uchida T., Takahashi H., Makita K., Arai H., Kijima S., Echizen H., Yasuhara M.: Population pharmacokinetics of cefazolin before, during, and after cardiopulmonary bypass in adult patients undergoing cardiac surgery, Eur. J. Clin. Pharmacol., 77(5), 735-745 (2021)
  • Kawano Y., Nagata M., Nakamura S., Akagi Y., Suzuki T., Tsukada E., Hoshiko M., Kujirai A., Nakamatsu S., Nishikawa T., Enomoto A., Negishi K., Shimada S., Aoyama T., Mano Y.: Comprehensive exploration of medications that affect the bleeding risk of oral anticoagulants users, Biol. Pharm. Bull., 44(5), 611-619 (2021)
  • Kawano Y., Katsuyama M., Nagata M., Obana M., Nakamatsu S., Mori A., Sakamoto N., Mano Y., Negishi K., Shimada S., Aoyama T.: Antiplatelet effect of mirtazapine via co-blocking of the 5-HT2A and α2-adrenergic receptors on platelets, Biol. Pharm. Bull., 44(2), 238-244 (2021)
  • Yanagie H., Fujino T., Yanagawa M., Terao T., Imagawa T., Fujihara M., Morishita Y., Mizumachi R., Murata Y., Dewi N., Ono Y., Ikushima I., Seguchi K., Nagata M., Nonaka Y., Furuya Y., Hisa T., Nagasaki T., Arimori K., Nakashima T., Sugihara T., Kakimi K., Ono M., Nakajima J., Eriguchi M., Higashi S., Takahashi H.: Tumor Growth Suppression With Novel Intra-arterial Chemotherapy Using Epirubicin-entrapped Water-in-oil-in-water Emulsion In Vivo., In vivo, 35(1), 239-248 (2021)
2019年
  • Suzuki S., Naito S., Numasawa Y., Asada M., Shoji N., Zeniya M., Takahashi D., Sato H., Iimori S., Nomura N., Sohara E., Okado T., Ishiwata Y., Nagata M., Rai T., Yokota T., Uchida S.: Encephalopathy induced by high plasma and cerebrospinal fluid ceftriaxone concentrations in a hemodialysis patient, Intern Med., 58(12), 1775-1779 (2019)
  • Takagi M., Ogawa C., Aoki-Nogami Y., Iehara T., Ishibashi E., Imai M., Kihara T., Nobori K., Hasebe K., Mizutani S., Kimura T., Nagata M., Yasuhara M., Yoshimura K., Yorozu P., Hosi H., Koike R.: Phase I clinical study of oral olaparib in pediatric patients with refractory solid tumors: Study protocol, BMC Pediatr., 19:31 (2019)
2018年
  • Ishiwata Y., Nagata M., Tsuge K., Takahashi H., Suzuki S., Imai K., Takagi M., Kanegane H., Morio T., Yasuhara M.: Population pharmacokinetics of intravenous busulfan in Japanese pediatric patients with primary immunodeficiency diseases, J. Clin. Pharmacol., 58(3), 327-331 (2018)
  • Nagata M., Kimura Y., Ishiwata Y., Takahashi H., Yasuhara M.: Clozapine-induced acute hyperglycemia is accompanied with elevated serum concentrations of adrenaline and glucagon in rats, Biol. Pharm. Bull., 41(8), 1286-1290 (2018)
  • Asada M., Nagata M., Mizuno T., Uchida T., Kurashima N., Takahashi H., Makita K., Arai H., Echizen H., Yasuhara M.: Effects of cardiopulmonary bypass on the disposition of cefazolin in patients undergoing cardiothoracic surgery, Pharmacol. Res. Perspect., 6(6), e00440 (2018)
2016年
  • M. Nagata , M. Nakajima, Y. Ishiwata, Y. Takahashi, H. Takahashi, K. Negishi,,and M. Yasuhara: Mechanism underlying induction of hyperglycemia in rats by single administration of olanzapine., Biol. Pharm. Bull., 39, 754-761 (2016).
  • Y. Ishiwata, M. Nagata , T. Arai, M. Makiishi, M. Yoshikawa, H. Takahashi, H. Kohsaka,,and M. Yasuhara: Effects of miconazole oral gel on blood concentrations of tacrolimus and cyclosporine: a retrospective observational study., Ther. Drug Monit., 38, 717-721 (2016).
2015年
  • M. Nagata , Y. Ishiwata, Y. Takahashi, H. Takahashi, K. Saito, Y. Fujii, K. Kihara,and M. Yasuhara: Pharmacokinetic-pharmacodynamic analysis of sunitinib-induced thrombocytopenia in Japanese patients with renal cell carcinoma., Biol. Pharm. Bull., 38, 402-410 (2015).
2013年
  • Y. Ishiwata, Y. Takahashi, M. Nagata , and M. Yasuhara: Effects of moxifloxacin on serum glucose concentrations in rats., Biol. Pharm. Bull., 36, 686-690 (2013).
2012年
  • Kawano Y., Nagata M., Kohno T., Ichimiya A., Iwakiri T., Okumura M., Arimori K.:Caffeine increases the antitumor effect of cisplatin in human hepatocellular carcinoma cells, Biol. Pharm. Bull., 35, 400-407 (2012).
  • T. Arino, S. Karakawa, Y. Ishiwata, M. Nagata, and M. Yasuhara: Effect of cimetidine on pentamidine induced hyperglycemia in rats. Eur. J. Pharmacol., 693, 72-79 (2012).
2011年
  • M. Nagata, Y. Hidaka, K. Hatakeyama, Y. Kawano, T. Iwakiri, M. Okumura, K. Arimori: Hepatic fibrosis does not affect the pharmacokinetics of 5-fluorouracil in rats, Biopharm. Drug Dispos., 32, 126-130 (2011).
  • Y. Takahashi, Y. Ishiwata, Y. Kojima and M. Yasuhara: Pharmacodynamics of cibenzoline-induced hypoglycemia in rats. Drug Metab. Pharmacokin., 36, 242-247 (2011).
2010年
  • M. Nagasawa, N. Mitsuiki, T. Ono, M. Takagi, H. Oda, M. Yasuhara and S. Mizutani: Pharmacokinetic monitoring is still required for intravenous busulfan in SCT for small children. Int. J. Hematol., 91, 728-730 (2010).
  • Y. Nakauchi, H. Takase, S. Sugita, M. Mochizuki, S. Shibata, Y. Ishiwata, Y. Shibuya, M. Yasuhara, O. Miura and A. Arai: Concurrent administration of intravenous systemic and intravitreal methotrexate for intraocular lymphoma with central nervous system involvement.Int. J. Hematol., 92, 179-185 (2010).
  • A. Hoshino, T. Iimura, S. Ueha, S. Hanada, Y. Maruoka, M. Mayahara, K. Suzuki, T. Imai, M. Ito, Y. Manome, M. Yasuhara, T. Kirino, A. Yamaguchi, K. Matsuhima and K. Yamamoto: Deficiency of chemokine receptor CCR1 causes osteopenia due to impaired functions of osteoclasts and osteoblasts. J. Biol. Chem., 285, 28826-28837 (2010).
  • M. Nagata, Y. Hidaka, M. Hidaka, Y. Kawano, T. Iwakiri, M. Okumura, K. Arimori: Effect of acute hepatic failure on the hepatic first-pass effect of 5-fluorouracil in rats., J. Pharm. Pharmacol., 62, 598-603 (2010).
  • Y. Ishiwata and M. Yasuhara: Gatifloxacin-induced histamine release and hyperglycemia in rats. Eur. J. Pharmacol., 645, 192-197 (2010).
2008年
  • A. Hoshino, T. Nagao, N. Nagi-Miura, N. Ohno, M. Yasuhara, K. Yamamoto, T. Nakayama and K. Suzuki: MPO-ANCA induces IL-17 production by activated neutrophils in vitro via classical complement pathway-dependent manner. J. Autoimmun., 31, 79-89 (2008).
  • A. Hoshino, N. Manabe, K. Fujioka, S. Hanada, M. Yasuhara, A. Kondo and K. Yamamoto: GFP expression by intracellular gene delivery of GFP-coding fragments using nanocrystal quantum dots. Nanotechnology, 19, 495102 (2008).
  • M. Nagata, Y. Matsuo, M. Hidaka, Y. Kawano, M. Okumura, J. Tokunaga, N. Takamura, K. Arimori: Effect of acute hepatic failure on epirubicin pharmacokinetics after intrahepatic arterial injection in rats., Biol. Pharm. Bull., 31, 493-496 (2008).
2007年
  • Y. Ishiwata, K. Son, Y. Itoga and M. Yasuhara: Effects of acute renal failure and ganciclovir on the pharmacodynamics of levofloxacin-induced seizures in rats. Biol. Pharm. Bull., 30, 745-750 (2007).
  • M. Nagata, M. Hidaka, H. Sekiya, Y. Kawano, K. Yamasaki, M. Okumura, K. Arimori: Effects of pomegranate juice on human cytochrome P450 2C9 (CYP2C9) and tolbutamide pharmacokinetics in rats., Drug Metab. Dispos., 35, 302-305 (2007).
  • A. Hoshino, Y.I. Kawamura, M. Yasuhara, M. Toyama-Sorimachi, K. Yamamoto, A. Matsukawa, S.A. Lira, and T. Dohi: Inhibition of CCL1-CCR8 interaction prevents aggregation of macrophages and development of peritoneal adhesions.J. Immunol., 178, 5296-5304 (2007).
  • A. Hoshino, T. Nagao, T. Ito-Ihara, A. Ishida-Okawara, K. Uno, E. Muso, N. Nagi-Miura, N. Ohno, K. Tokunaka, S. Naoe, H. Hashimoto, M. Yasuhara, K. Yamamoto and K Suzuki: Trafficking of QD-conjugated MPO-ANCA in murine systemic vasculitis and glomerulonephritis model mice. Microbiol. Immunol., 51, 551-566 (2007).
  • A. Hoshino, N. Ohnishi, M. Yasuhara, K. Yamamoto and A. Kondo: Separation of murine neutrophils and macrophages by thermoresponsive magnetic nanoparticles. Biotechnol. Progress, 23, 1513-1516 (2007).
  • A. Hoshino, T. Nagao, A. Nakasuga, A. Ishida-Okawara, K. Suzuki, M. Yasuhara and K. Yamamoto: Nanocrystal quantum dot-conjugated anti-myeloperoxidase antibody as the detector of activated neutrophils. IEEE Transact. Nanobiosci., 6, 341-345 (2007).
  • A. Hoshino, K.Omata, S. Takami, T. Adschiri, N. Terada, T. Funatsu, M. Yasuhara and K. Yamamoto: Fluorescence millisecond oscillation in polar solvents regulates fluorescence intensity of colloidal quantum dots’solution. J. Nanophotonics, 1, 013516 (2007).
2006年
  • Y. Ishiwata, Y. Sanada and M. Yasuhara: Effects of gatifloxacin on serum glucose concentration in normal and diabetic rats.Biol. Pharm. Bull., 29, 527-531 (2006).
  • Y. Ishiwata, Y. Itoga and M. Yasuhara: Effect of levofloxacin on serum glucose concentration in rats.Eur. J. Pharmacol., 551, 168-174 (2006).
2005年
  • Y. Ishiwata, M. Nagata and M. Yasuhara: Effect of isoniazid on the pharmacodynamics of cefazolin-induced seizures in rats. Drug Metab. Pharmacokin., 20, 117-120 (2005).
  • A. Hoshino, K. Fujioka, N. Manabe, S. Yamaya, Y. Goto, M. Yasuhara and K. Yamamoto: Simultaneous multicolor detection system of the single-molecular microbial antigen with total internal reflection fluorescence microscopy. Microbiol. Immunol., 49, 461-470 (2005).
2004年
  • A. Hoshino, K. Fujioka, T. Oku, M. Suga, Y.F. Sasaki, T. Ohta, M. Yasuhara, K. Suzuki and K. Yamamoto: Physicochemical properties and cellular toxicity of nanocrystal quantum dots depend on their surface modification. Nano Lett., 4, 2163-2169 (2004).
  • A. Hoshino, K. Fujioka, T. Oku, S. Nakamura, M. Suga, Y. Yamaguchi, M. Yasuhara and K. Yamamoto: Quantum dots targeted to the assigned organelle in living cells. Microbiol. Immunol., 48, 985-994 (2004).
2003年
  • H. Okabe, A. Mizukami, M. Taguchi, T. Aiba, M. Yasuhara and Y. Hashimoto: The increased intestinal absorption rate is responsible for the reduced hepatic first-pass extraction of propranolol in rats with cisplatin-induced renal dysfunction. J. Pharm. Pharmacol., 55, 479-486 (2003).
  • M. Nagata, T. Fujichika and M. Yasuhara: Effect of experimental renal failure and hypotonic hyponatremia on the pharmacodynamics of cefazolin-induced seizures in rats. Pharm. Res., 20, 937-942 (2003).
2002年
  • T. Yoshitani, H. Yagi, N. Inotsume and M. Yasuhara: Effect of experimental renal failure on the pharmacokinetics of losartan in rats. Biol. Pharm. Bull., 25, 1077-1083 (2002).
2001年
  • Y. He, N. Kitada, M. Yasuhara and R. Hori: Quantitative estimation of renal clearance of N-acetylprocainamide in rats with various experimental acute renal failure. Eur. J. Pharm. Sci., 13, 303-308 (2001).
  • Y. Hashimoto, T. Aiba, M. Yasuhara and R. Hori: Effect of experimental renal dysfunction on bioavailability of ajmaline in rats. J. Pharm. Pharmacol., 53, 805-813 (2001).
  • M. Nagata and M. Yasuhara: Effect of experimental renal failure on the pharmacodynamics of cefoselis-induced seizures in rats. Biol. Pharm. Bull., 24, 1049-1052 (2001).

原著論文(和文)

  • 清水能子, 磯野義寿, 石川雅啓, 小林悟, 安原眞人, 副作用・感染症情報収集の現状と隘路, 日本病院薬剤師会雑誌, 38, 51-53 (2002).
  • 青木由貴, 高木正稔, 前田佳真, 新井洋美, 高橋真弓, 柴田聡子, 磯田健志, 満生紀子, 長澤正之, 森尾友宏, 安原眞人, 水谷修紀, 化学療法抵抗性を示したWilms腫瘍に対する薬物動態解析にもとづくトポテカン(ノギテカン)の投与経験, 小児がん, 46, 337-342 (2009).
  • 高木彰紀,永田将司,岩切智美,奥村学,有森和彦:バンコマイシン初回投与設計時における新規日本人向けGFR推算式の評価-Cockcroft & Gault式との比較-,医療薬学,36,587-591 (2010).