Name of Division: Laboratory Medicine

Staff

Education

　　Preface

　Division of Laboratory Medicine is denoted to the education and research work of laboratory medicine, which includes clinical biochemistry, clinical hematology, clinical immunology, clinical physiology and medical informatics.

　　Undergraduate Course

　 All medical students in their fifth school year are obliged to study laboratory medicine. The curriculum consists of the lectures on all fields of laboratory medicine, clinical conference and practical training mastering fundamental laboratory technology. The goals of laboratory medicine education for undergraduate medical students are for them to acquire basic knowledge about laboratory medicine and to learn basic skills for fundamental medical technology.

　　Graduate Course

　The principle purpose of postgraduate education is to provide the highest-quality education in the field of laboratory medicine for those who have the potential to excel in research and education. There are two kinds of postgraduate students; one is the full-time postgraduate doctoral-course and master-course and the other is the special-course of selected programs. The goals of laboratory medicine education for postgraduate students are to enable them to obtain advanced knowledge and high-quality skills in laboratory medicine.

　

Research Subjects

1. To develop and apply DNA analysis in the diagnosis of cancer, infectious diseases or some other diseases.

2. To determine the leukemogenesis and the mechanisms of leukemic cells growth. This kind of study is based on cell biology and molecular biology.

3. To develop the automation system for clinical laboratory.

4. To develop the expert system for data analysis.

　

Publications

2001

１．Tohda S, Murakami N, and Nara N: Human herpesvirus 8 DNA in HIV-negative Japanese patients with multicentric Castleman's disease and related diseases. International Journal of Molecular Medicine 5:549-551, 2001.

２．Tohda S and Nara N: Expression of Notch1 and Jagged1 proteins in acute myeloid leukemia cells. Leukemia and Lymphoma 42: 467-472, 2001.

３．Inaba A, Yokota T, Saito Y, Ichikawa T, Mizusawa H. Proximal motor conduction evaluated by transcranial magnetic stimulation in acquired inflammatory demyelinating neuropathies. Clin Neurophysiol 112;2001:1936-1945.

４．Kohyama J, Ohinata J, Hasegawa T. Disturbance of phasic chin muscle activity during rapid-eye-movement sleep. Brain Dev 2001; 23 Suppl 1:S104-7.

５．Kohyama J, Shiiki T, Shimohira M, Hasegawa T. Asynchronous breathing during sleep. Arch Dis Child 2001; 84:174-7.

６．Masahiro NISHIBORI : Proposal for Standardization of Digital Color Imaging in Morphological Laboratory Diagnosis. Digital Color Imaging in Biomedicine, 53-60, 2001.02.28

７．Masahiro NISHIBORI : Making the First Textbook: 'Digital Color Imaging in Biomedicine'. Proceedings of the 3rd International Conference on Multispectral Color Science (MCS'01), 17-20, 2001.06.18

2000

1.　Tohda S, Murakami N, Nara N. Polymerase chain reaction detection of rearranged immunoglobulin heavy chain DNA in plasma samples is useful in the diagnosis of B-cell lymphoma. Int J Hematol 2000; 72: 74-78.

2.　Tohda S, Ohkusa T. Resolution of refractory idiopathic thrombocytopenic purpura after eradication of Helicobactor pyroli. (letter) Am J Hematol 2000; 65: 329-330.

3. Ohsawa M, Koyama T, Shibakura M, Kamei S, Hirosawa S. Arsenic trioxide (As2O3) gradually downregulates tissue factor expression without affecting thrombomodulin expression in acute promyelocytic leukemia cells. Leukemia 2000; 14: 941-3.

4. Ohsawa M, Koyama T, Yamada K, Hirosawa S, Kamei S, Kamiyama R. 1α,25-Dihydroxyvitamin D3 and its potent synthetic analogs downregulate tissue factor and upregulate thrombomodulin expression in monocytic cells, counteracting the effects of tumor necrosis factor and oxidized LDL. Circulation 2000; 102: 2867-72.

5.　 Nishibori M. Problems and Solutions in Medical Color Imaging. Proceedings of Second International Symposium on Multispectral Imaging and High Accurate Color Reprocuction 2000;9-17.

6. Hasegawa T, Azuma S, Inoue S. Amino acid release from the rat oral pontine reticular nucleus across the sleep-wakefulness cycle. J Med Dent Sci 2000; 47: 87-93.

7. Kohyama J, Shiiki T, Hasegawa T. Sleep duration of young children is affected by nocturnal sleep time. Pediatr Int 2000; 42: 589-91.

　

[Graduate School, School of Medicine]

［TOKYO MEDICAL AND DENTAL UNIVERSITY］