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ホーム  > 口腔放射線腫瘍学分野  > 業績集  > 原著論文

原著論文

Sato M, Saito Y, Takayama T, Omata T, Watanabe H,Yoshimura R, Miura M: Remote radioactive seed-loading device for permanent brachytherapy of oral cancer with Au-198 grains. ROBOMECH J, 4: 23, 2017

Ozaki Y, Watanabe H, Kaida A, Miura M, Nakagawa K, Toda K, Yoshimura R, Sumi Y, Kurabayashi T: Estimation of whole-body radiation exposure from brachytherapy for oral cancer using a Monte Carlo simulation. J Radiat Res, 24:1-6, 2017

Oba A, Shimada S, Akiyama Y, Nishikawaji T, Mogushi K, Ito H, Matsumura S, Aihara A, Mitsunori Y, Ban D, Ochiai T, Kudo A, Asahara H, Kaida A, Miura M, Tanabe M, Tanaka S: ARID2 modulates DNA damage response in human hepatocellular carcinoma cells. J Hepatol, 66:942-951, 2017

Onozato Y, Kaida A, Harada H, Miura: Radiosensitivitiy of quiescent and proliferating cells grown as multicellular tumor spheroids. Cancer Sci, 108:704-712, 2017

Kaida A, Watanabe H, Toda K, Yuasa-Nakagawa K, Yoshimura R, Miura M: Effects of dose rate on early and late complications in low dose rate brachytherapy for mobile tongue carcinoma using 192Ir sources. Oral Radiol, 33:187-192, 2017

Manila N, Kaida A, Miura M: Kinetic Analysis of Radiation-induced Cell-cycle Alterations in HeLa Cells Expressing Fluorescent Ubiquitination-based Cell Cycle Indicator (Fucci). Radiation Environment and Medicine, 5:2, 2016

Asahina T, Kaida A, Goto T, Yoshimura R, Sasai K, Miura M: Temporo-spatial cell-cycle kinetics in HeLa cells irradiated by Ir-192 high dose-rate remote afterloading system (HDR-RALS). Radiat Oncol, 11:99, 2016

Okuyama K, Kaida A, Hayashi Y, Hayashi Y, Harada K, Miura M: KPU-300, a Novel Benzophenone-Diketopiperazine-Type Anti-Microtubule Agent with a 2-Pyridyl Structure, Is a Potent Radiosensitizer That Synchronizes the Cell Cycle in Early M Phase. PLoS One, 10: e0145995, 2015

Goto T, Kaida A, Miura M: Visualizing cell-cycle kinetics after hypoxia/reoxygenation in HeLa cells expressing fluorescent ubiquitination-based cell cycle indicator (Fucci). Exp Cell Res, 339:389-96, 2015

Izaguirre-Carbonell J, Kawakubo H, Murata H, Tanabe A, Takeuchi T, Kusayanagi T, Tsukuda S, Hirakawa T, Iwabata K, Kanai Y, Ohta K, Miura M, Sakaguchi K, Matsunaga S, Sahara H, Kamisuki S, Sugawara F: Novel anticancer agent, SQAP, binds to focal adhesion kinase and modulates its activity. Sci Rep, 5:15136, 2015

Kaida A, Miura M: Unusual prolongation of radiation-induced G2 arrest in tumor xenografts derived from HeLa cells. Cancer Sci, 106:1370-6, 2015

Tsuchida E, Kaida A, Pratama E, Ikeda MA, Suzuki K, Harada K, Miura M: Effect of X-Irradiation at Different Stages in the Cell Cycle on Individual Cell-Based Kinetics in an Asynchronous Cell Population. PLoS One, 10: e0128090, 2015

Sawada Y, Omoto K, Kohei N, Sakaguchi K, Miura M, Tanabe K: Sulfoquinovosylacylpropanediol is a novel potent radiosensitizer in prostate cancer. Int J Urol, 22: 590-5, 2015

Yamada C, Kaida A, Okuyama K, Harada K, Miura M: Effects of Chk1 inhibitor or paclitaxel on cisplatin-induced cell-cycle kinetics and survival in parental and cisplatin-resistant HeLa cells expressing fluorescent ubiquitination based cell cycle indicator (Fucci). Integr Cancer Sci Therap, 2: 87-92, 2015

Eslami A, Miyaguchi K, Mogushi K, Watanabe H, Okada N, Shibuya H, Mizushima H, Miura M, Tanaka H: PARVB overexpression increases cell migration capability and defines high risk for endophytic growth and metastasis in tongue squamous cell carcinoma. Br J Cancer, 112: 338-44, 2015

Xue L, Furusawa Y, Okayasu R, Miura M, Cui X, Liu C, Hirayama R, Matsumoto Y, Yajima H, Yu D: The complexity of DNA double strand break is a crucial factor for activating ATR signaling pathway for G2/M checkpoint regulation regardless of ATM function. DNA Repair (Amst), 25: 72-83, 2015

Hayashi Y, Takeno H, Chinen T, Muguruma K, Okuyama K, Taguchi A, Takayama K, Yakushiji F, Miura M, Usui T, Hayashi Y: Development of a new benzophenone-diketopiperazine-type potent antimicrotubule agent possessing a 2-pyridine structure. ACS Med Chem Lett, 5: 1094-8, 2014

Nahar K*, Goto T*, Kaida A, Deguchi S, Miura M.: Effects of Chk1 inhibition on the temporal duration of radiation-induced G2 arrest in HeLa cells. J Radiat Res, 55: 1021-7, 2014
*Equal contribution

Kaida A, Miura M: Visualizing the effect of tumor microenvironments on radiation-induced cell kinetics in multicellular spheroids consisting of HeLa cells. Biochem Biophys Res Commun, 439: 453-458, 2013

Yuasa-Nakagawa K, Shibuya H, Yoshimura R, Miura M, Watanabe H, Kishimoto S, Omura K: Cervical lymph node metastasis from early-stage squamous cell carcinoma of the oral tongue. Acta Otolaryngol. 133: 544-551, 2013

Honda-Uezono A, Kaida A, Michi Y, Harada K, Hayashi Y, Hayashi Y, Miura M: Unusual expression of red fluorescence at M phase induced by anti-microtubule agents in HeLa cells expressing the fluorescent ubiquitination-based cell cycle indicator (Fucci). Biochem Biophys Res Commun, 428:224-229, 2012

Abe S, Hamada K, Miura M, Yamaguchi S: Neural crest stem cell property of apical pulp cells derived from human developing tooth. Cell Biol Int, 36: 927-936, 2012

Miyano Y, Tsukuda S, Sakimoto I, Takeuchi R, Shimura S, Takahashi N, Kusayanagi T, Takakusagi Y, Okado M, Matsumoto Y, Takakusagi K, Takeuchi T, Kamisuki S, Nakazaki A, Ohta K, Miura M, Kuramochi K, Mizushina Y, Kobayashi S, Sugawara F, Sakaguchi K:Exploration of the binding proteins of perfluorooctane sulfonate by a T7 phage display screen. Bioorg Med Chem, 20: 3985-3990, 2012

Kaida A, Miura M: Differential dependence on oxygen tension during the maturation process between monomeric Kusabira Orange 2 and monomeric Azami Green expressed in HeLa cells. Biochem Biophys Res Commun, 421:855-859, 2012

Kaida A, Miura M: Visualizing the effect of hypoxia on fluorescence kinetics in living HeLa cells using the fluorescent ubiquitination-based cell cycle indicator (Fucci). Exp Cell Res, 318:288-297, 2012

Yoshimura R, Shibuya H, Hayashi K, Nakagawa K, Toda K, Watanabe H, Kaida A, Miura M:Repeat brachytherapy for patients with residual or recurrent tumors of oral cavity. Int J Radiat Oncol Biol Phys, 83:1198-1204, 2012

Nakayama M, Kaida A, Deguchi S, Sakaguchi K, Miura M: Radiosensitivity of early and late M-phase HeLa cells isolated by a combination of Fluorescence ubiquitination-based cell cycle indicator (Fucci) and mitotic shake-off. Radiat Res, 176: 407-411, 2011

Yoshimura R, Shibuya H, Hayashi K, Toda K, Watanabe H, Miura M:Disease control using low-dose-rate brachytherapy is unaffected by comorbid severity in oral cancer patients. Br J Radiol, 84: 930-938, 2011

Abe S, Hamada K, Yamaguchi S, Amagasa T, Miura M: Characterization of the radioresponse of human apical papilla-derived cells (APDCs). Stem Cell Res Ther, 2:2, 2011

Kaida A, Sawai N, Sakaguchi K, Miura M: Fluorescence kinetics in HeLa cells after treatment with cell cycle arrest inducers visualized with the Fucci (fluorescent ubiquitination-based cell cycle indicator). Cell Biol Int, 35: 359-363, 2011

Ohta K, Murata H, Mori Y, Ishima M, Sugawara F, Sakaguchi K, Miura M: Remodeling of the tumor microenvironment by combined treatment with a novel radiosensitizer, α-sulfoquinovosylmonoacylglycerol (α-SQMG) and X-irradiation. Anticancer Res, 30: 4397-4404, 2010

Ishikawa M, Ogihara Y, Miura M: Visualization of radiation-induced cell cycle-associated events in tumor cells expressing the fusion protein of Azami Green and the destruction box of human geminin. Biochem Biophys Res Commun, 389, 426-430, 2009

Sermsathanasawad N, Ishii H, Igarashi K, Miura M, Yoshida M, Inoue Y, Iwai T.: Enhanced adhesion of early endothelial progenitor cells to radiation-induced senescence-like vascular endothelial cells in vitro. J Radiat Res, 50, 469-475, 2009

Yoshimura R, Shibuya H, Miura M, Watanabe H, Ayukawa F, Hayashi K, Toda K: Quality of life of oral cancer patients after low-dose-rate interstitial brachytherapy. Int J Radiat Oncol Biol Phys, 73, 772-778, 2009

Igarashi K, Miura M: Inhibition of a Radiation-induced Senescence-like Phenotype: A possible mechanism for potentially lethal damage repair in vascular endothelial Cells. Radiat Res, 170, 534-539, 2008

Mori Y, Sahara H, Matsumoto K, Takahashi N, Yamazaki T, Ohta K, Aoki S, Miura M, Sugawara F, Sakaguchi K, Sato N: Down-regulation of Tie2 by novel antitumor sulfolipid 3’-sulfoquinovosyl-1’-monoacylglycerol, targeting angiogenesis. Cancer Sci, 99, 1063-1070, 2008

Watanabe H, Mogushi K, Miura M, Yoshimura R, Kurabayashi T, Shibuya H, Tanaka H, Noda S, Iwakawa M, Imai T: Prediction of lymphatic metastasis based on gene expression profile analysis after brachytherapy for early-stage oral tongue carcinoma. Radiother Oncol, 87, 237-242, 2008

Kaneko H, Yu D, Miura M: Overexpression of IGF-I receptor in HeLa Cells enhances in vivo radioresponse. Biochem Biophys Res Commun, 363, 937-941, 2007

Igarashi K, Sakimoto I, Kataoka K, Ohta K, Miura M: Radiation-induced senescence-like phenotype in proliferating and plateau-phase vascular endothelial cells. Exp Cell Res, 313, 3326-3336, 2007

Ayukawa F, Shibuya H, Yoshimura R, Watanabe Y, Miura M: Curative brachytherapy for recurrent/residual tongue cancer. Strahlenther Onkol, 183, 133-137, 2007

Kishino M, Shibuya H, Yoshimura R, Miura M, Watanabe H: A retrospective analysis of the use of brachytherapy in relation to early stage squamous cell carcinoma of the oropharynx and its relationship to second primary respiratory and upper digestive tract cancers. Brit J Radiol, 80, 121-125, 2007

Aoki, S, Ohta K., Matumoto K., Sakai H, Abe, M, and Miura M, Sugawara F, Sakaguchi K: An emulsion of sulfoquinovosylacylglycerol with long-chain alkanes increases its permeability to tumor cells. J Membr Biol, 213, 11-18, 2006

Oota S, Shibuya H, Yoshimura R, Watanabe H, Miura M: Brachytherapy of stage II mobile tongue carcinoma. prediction of local control and QOL. Radiat Oncol, 1,21-28, 2006

Sakimoto I, Ohta K, Yamazaki T, Ohtani S, Sahara H, Sugawara F, Sakaguchi K, Miura M: -Sulfoquinovosylmonoacylglycerol is a novel potent radiosensitizer targeting tumor angiogenesis. Cancer Res, 66, 2287-2295, 2006

Watanabe H, Murata Y, Miura M, Hasegawa M, Kawamoto T, Shibuya H : In vivo visualization of radiation-induced apoptosis using 125I-annexin V. Nucl Med Commun, 27, 81-89, 2006

Ihara N, Shibuya H, Yoshimura R, Oota S, Miura M, Watanabe H: Interstitial brachytherapy for stage III squamous cell carcinoma of the mobile tongue; The relationship between sub-stages and prognostic factors. Acta Oncol, 44, 709-716, 2005

Kaneko H, Igarashi K, Kataoka K, Miura M: Heat shock induces phosphorylation o f histone H2AX in mammalian cells. Biochem Biophys Res Commun, 328, 1101-1106, 2005

Kuribayashi A, Kataoka K, Kurabayashi T, Miura M: Evidence that basal activity, but not transactivation, of the epidermal growth factor receptor tyrosine kinase is required for insulin-like growth factor I-induced activation of extracellular signal-regulated kinase in oral carcinoma cells. Endocrinology, 145, 4976-4984, 2004

Watanabe H, Kurabayashi T, Miura M: Inhibition of the extracellular signal-regulated kinase (ERK) pathway and the induction of radioresistance in rat 3Y1 cells. Int J Radiat Biol, 80, 451-456, 2004

Hoshina M, Shibuya H, Kubo H D, Miura M, Ohashi I, Yoshimura R, Oota S : Determination of depth of 50% maximum ionization, I50, for electron beams by divided difference methods. Med Phys, 31, 2068-2074, 2004

Kataoka K, Yu D, Miura M: Activation of the phosphatidylinositol-3' kinase pathway and DNA synthesis by a mutant insulin-like growth factor I receptor lacking the NPXY motif. J Endocrinol, 181, 139-146, 2004

Kataoka K, Miura M: Insulin-like growth factor I receptor does not contribute to heat shock-induced activation of Akt and extracellular signal-regulated kinase (ERK) in mouse embryo fibroblasts. J Radiat Res, 45, 141-144, 2004

Yu D, Shibuya H, Miura M: Roles of the insulin-like growth factor I receptor C-terminus in cellular radioresistance. Biochem Biophys Res Commun, 311, 174-178, 2003

Yu D, Watanabe H, Shibuya H, Miura M: Redundancy of radioresistant signaling pathways originating from insulin-like growth factor I receptor. J Biol Chem, 278, 6702-6709, 2003

Nakagawa T, Shibuya H, Yoshimura R, Miura M, Okada N, Kishimoto S, Amagasa M, Omura K: Neck node metastasis after successful brachytherapy for early stage tongue carcinoma. Radiother Oncol, 68, 129-135, 2003

Imoto I, Tsuda H, Hirasawa A, Miura M, Sakamoto M, Hirohashi S, Inazawa, J: Expression of cIAP1, a target for 11q22 amplification, correlates with resistance of cervical cancers to radiotherapy. Cancer Res, 62, 4860-4866, 2002

Watanabe H, Yu D, Sasaki T, Shibuya H, Hosoi Y, Asada M, Komatsu K, Miura M: Insulin-like growth factor I receptor is expressed at normal levels in Nijmegen breakage syndrome cells. Biochem Biophys Res Commun, 296, 62-66, 2002

Yu D, Watanabe H, Shibuya H, Miura M: The phosphatidylinositol-3 kinase pathway is not essential for insulin-like growth factor I receptor-mediated clonogenic radioresistance. J Radiat Res, 43, 325-329, 2002

Yoshimura R, Shibuya H, Ogura I, Miura M, Amagasa T, Enomoto S, Kishimoto S : Trimodal combination therapy for maxillary sinus carcinoma. Int J Radiat Oncol Biol Phys, 53, 656-663, 2002

Yamamoto E, Shibuya H, Yoshimura R, Miura M: Site specific dependency of second primary cancer in early stage head and neck squamous cell carcinoma. Cancer, 94, 2007-2014, 2002

Tezuka M, Watanabe H, Nakamura S, Yu D, Aung W, Sasaki T, Shibuya H, Miura M: Antiapoptotic activity is dispensable for insulin-like growth factor-I receptor-mediated clonogenic radioresistance after gamma-irradiation. Clin Cancer Res, 7, 3206-3214, 2001

Miura M, Watanabe H, Sasaki T, Tatsumi K, Muto M: Dynamic changes in subnuclear NP95 location during the cell cycle and its spatial relationship with DNA replication foci. Exp Cell Res, 263, 202-208, 2001

Miura M, Watanabe H, Okochi K, Sasaki T, Shibuya H: Biological response to ionizing radiation in mouse embryo fibroblasts with a targeted disruption of the DNA polymerase beta gene. Radiat Res, 153, 773-780, 2000

Yoshimura R, Shibuya H, Hoshina M, Akaike H, Takeda M, Fukuda H, Hoshi A, Miura M: Successful interstitial treatment for bilateral tongue cancer. Br J Radiol, 72, 812-814, 1999

Watanabe H, Miura M, Sasaki T: Differential effects of the insulin-like growth factor I receptor on radiosensitivity and spontaneous necrosis formation of human glioblastoma cells grown in spheroids. Exp Cell Res, 50, 99-111, 1999

Miura M, Takeda M, Sasaki T, Inoue T, Nakayama T, Fukuda H, Hoshi A, Hoshina M, Shibuya H: Factors affecting mandibular complications in low dose-rate brachytherapy for oral tongue carcinoma with special reference to spacer. Int J Radiat Oncol Biol Phys, 41, 763-770, 1998

Miura M, Baserga R: The tyrosine residue at 1250 of the insulin-like growth factor I receptor is required for ligand-mediated internalization. Biochem Biophys Res Commun. 239, 182-185,1997

Nakamura S, Watanabe S, Miura M, Sasaki T: Effect of the insulin-like growth factor I receptor on ionizing radiation-induced cell death in mouse embryo fibroblasts. Exp Cell Res, 235, 287-294, 1997

Wang Y, Cheong N, Miura M, Iliakis G: Overexpression of insulin-like growth factor (IGF)-I receptor enhances inhibition of DNA replication in mouse cells exposed to x-rays. Radiat Environ Biophys, 36, 117-123, 1997

Miura M, Sasaki T: Effect of XPA gene mutations on UV-induced immunostaining of PCNA in fibroblasts from xeroderma pigmentosum group A patients. Mutat Res (DNA Repair), 364, 51-56,1996

Miura M, Nakamura S, Sasaki T, Takasaki Y, Shiomi T, Yamaizumi M: Roles of XPG and XPF/ERCC1 endonucleases in UV-induced immunostaining of PCNA in fibroblasts. Exp Cell Res, 226, 126-132, 1996

Hongo A, D'ambrosio C, Miura M, Morrione A, Baserga R: Mutational analysis of the mitogenic and transforming activities of the insulin-like growth factor I receptor. Oncogene, 12, 1231-1238, 1996

Miura M, Sasaki T, Takasaki Y: Characterization of X-ray-induced immunostaining of PCNA in human diploid fibroblasts. Radiat Res, 145, 73-78, 1996

Miura M, Surmacz E, Burgaud, J-L, Baserga R: Different effects on mitogenesis and transformation of a mutation at tyrosine 1251 of the insulin-like growth factor I receptor. J Biol Chem, 270, 22639-22644, 1995

Miura M, Li S, Baserga R: Effect of a mutation at tyrosine 950 of the insulin-like growth factor I receptor on the growth and transformation of cells. Cancer Res, 55, 663-667, 1995

Li S, Ferber A, Miura M, Baserga R: Mitogenicity and transforming ability of the insulin-like growth factor I receptor with mutations in the tyrosine kinase domain. J Biol Chem, 269, 32558-32564, 1994

Coppola D, Ferber A, Miura M, Sell C, D'Ambrosio C, Rubin R, Baserga R: A functional insulin-like growth factor I receptor is required for the mitogenic and transforming activities of the epidermal growth factor receptor. Mol Cell Biol, 14, 4588-4595, 1994

Sell C, Dumenil G, Devaud C, Miura M, Coppola D, Efstratiadis A, Baserga R: Effect of a null mutation of insulin-like growth factor I receptor gene on growth and transformation of mouse embryo fibroblasts. Mol Cell Biol, 14, 3604-3612, 1994

Miura M, Li S Dumenil, G, Baserga R: Platelet-derived growth factor-induced expression of messenger RNA for the proliferating cell nuclear antigen (PCNA) requires a functional receptor for the insulin-like growth factor I. Cancer Res, 54, 2472-2477, 1994

Ambrose D, Resnicoff M, Coppola D, Sell C, Miura M, Jameson S, Baserga R, Rubin, R: Growth regulation of human glioblastoma T98G cells by insulin-like growth factor-1 and its receptor. J Cell Physiol, 159, 92-100, 1994

Yoshinouchi M, Miura M, Gaozza E, Li S, Baserga R: Basic fibroblast growth factor stimulates DNA synthesis in cells overexpressing the insulin-like growth factor I receptor. Mol Endocrinol, 7, 1161-1168, 1993

Miura M, Domon M, Sasaki, T, Kondo S, Takasaki Y: Restoration of proliferating cell nuclear antigen (PCNA) complex formation in xeroderma pigmentosum group A cells following cis-diamminedichloroplatinum(II) treatment by cell fusion with normal cells. J Cell Physiol, 152, 639-645, 1992

Miura M, Domon M, Sasaki T, Takasaki Y: Induction of proliferating cell nuclear antigen (PCNA) complex formation in quiescent fibroblasts from a xeroderma pigmentosum patient. J Cell Physiol, 150, 370-376, 1992

Miura M, Domon M, Sasaki T, Kondo S, Takasaki Y: Two types of proliferating cell nuclear antigen (PCNA) complex formation in quiescent normal and xeroderma pigmentosum group A fibroblasts following ultraviolet light (UV) irradiation. Exp Cell Res, 201, 541-544, 1992

Miura M, Sasaki T: Role of glutathione in the intrinsic radioresistance of cell lines from a mouse squamous cell carcinoma. Radiat Res, 126, 229-236, 1991

Miura M, Sasaki T: Relationship between radiosensitivity and metallothionein content in clones from a mouse squamous cell carcinoma. Radiat Res, 123, 171-175, 1990