大学院保健衛生学研究科
分子生命情報解析学分野（赤澤研）
研究業績
2015年
T. Yasui, Y. Mabuchi, H. Toriumi5, T. Ebine,
K. Niibe, D.D. Houlihan, S.
Morikawa, K. Onizawa, H. Kawana, C. Akazawa,
N. Suzuki,
T. Nakagawa, H. Okano, and Y. Matsuzaki
Purified
Human Dental Pulp Stem Cells Promote Osteogenic
Regeneration.
Journal of
Dental Research 2015 (In press)
Ogata
Y, Mabuchi Y, Yoshida M, Suto EG, Suzuki N, Muneta T, Sekiya I, and Akazawa C.
Purified
human synovium mesenchymal stem cells as a good
resource for cartilage regeneration.
PLoS
One. 2015 Jun 8;10(6):e0129096.
doi:
10.1371/journal.pone.0129096. PubMed
Ishii
K, Suzuki N, Mabuchi Y, Ito N, Fukada S, Okano H, Takeda S, and Akazawa C.
Suppressive Function of
Teneurin-4 in Proliferation and Differentiation of Muscle Satellite Cells for Tissue
Regeneration.
Stem Cells. 2015 Oct;33(10):3017-27. doi:
10.1002/stem.2058. PubMed
Ozeki N, Muneta
T, Matsuta S, Koga H, Nakagawa Y, Mizuno M, Tsuji K,
Mabuchi Y, Akazawa C, Kobayashi E, Saito T, Sekiya I.
Synovial
mesenchymal stem cells promote meniscus regeneration augmented by an autologous
achilles tendon graft in a rat partial meniscus defect
model.
Stem
Cells.
2015 Jun;33(6):1927-38. doi: 10.1002/stem.2030. PubMed
Suto EG, Mabuchi Y,
Suzuki N, Koyanagi A, Kawabata Y, Ogata Y, Ozeki Y, Muneta Y, Sekiya I, Akazawa C.
High capacity of purified mesenchymal stem cells for cartilage
regeneration.
Inflammation and Regeneration Mar:34(2):78-85. doi: http://doi.org/10.2492/inflammregen.35.078 J-STAGE
2014年
Lin
X, Yang T, Wang S, Wang Z, Yun Y, Sun L, Zhou Y, Xu
X, Akazawa C, Hong W, Wang T.
RILP
interacts with HOPS complex via VPS41 subunit to regulate endocytic
trafficking.
Scientific
Reports. 2014 Dec 2;4:7282. doi: 10.1038/srep07282. Pub Med
Suzuki
N, Mizuniwa C, Ishii K, Nakagawa Y, Tsuji K, Muneta T, Sekiya I, Akazawa C.
Teneurin-4,
a transmembrane protein, is a novel regulator that suppresses
chondrogenic differentiation.
J
Orthop Res. 2014 Mar 20. doi: 10.1002/jor.22616. Pub Med
Suzuki
R, Miyahara K, Murakami H, Doi T, Lane GJ, Mabuchi Y,
Suzuki N, Yamataka A, Akazawa C.
Abnormal neural crest innervation in Sox10-Venus
mice with all-trans retinoic acid-induced anorectal
malformations.
Pediatr Surg
Int.
2014 Feb;30(2):189-95. doi: 10.1007/s00383-013-3452-z. Pub Med
Suzuki
N, Numakawa T, Chou J, de Vega S, Mizuniwa
C, Sekimoto K, Adachi N, Kunugi H, Arikawa-Hirasawa E, Yamada Y, Akazawa C.
Teneurin-4
promotes cellular protrusion formation and neurite outgrowth through focal
adhesion kinase signaling.
FASEB
J. 2014
Mar;28(3):1386-97. doi: 10.1096/fj.13-241034. Epub 2013 Dec 16. Pub Med
2013年
Nakazawa N, Miyahara K, Okawada M, Yamataka A, Suzuki R, Akazawa C, Tomikawa-Ichikawa
N, Arikawa-Hirasawa E:
Laminin-1
promotes enteric nervous system development in mouse embryo.
Pediatr Surg
Int.
2013 Nov;29(11):1205-8. doi: 10.1007/s00383-013-3388-3. Pub Med
Mabuchi
Y, Morikawa S, Harada S, Niibe
K, Suzuki S, Renault-Mihara F, Houlihan
DD, Akazawa C, Okano H, Matsuzaki
Y:
LNGFR(+)THY-1(+)VCAM-1(hi+) cells reveal functionally
distinct subpopulations in mesenchymal stem cells.
Stem Cell Rep.
2013 Jul 1(2): 152-165. doi:
10.1016/j.stemcr.2013.06.001
Pub Med
Sato
H, Shibata M, Shimizu T, Shibata S, Toriumi H, Ebine T, Kuroi T, Iwashita T, Funakubo M, Kayama Y, Akazawa
C, Wajima K, Nakagawa T, Okano H, Suzuki N:
Differential cellular localization of antioxidant
enzymes in the trigeminal ganglion.
Neuroscience. 2013 Jun 15;248C:345-358. doi:
10.1016/j.neuroscience.2013.06.010. Pub Med
Mabuchi Y, Houlihan DD, Akazawa
C, Okano H, Matsuzaki Y:
Prospective isolation of murine and human bone marrow mesenchymal stem cells based on surface markers.
Stem Cells Int.
2013 May 2013:507301.
doi: 10.1155/2013/507301. Pub Med
Ohtomo R, Mori T, Shibata S, Tsuta K, Maeshima AM, Akazawa C,
Watabe Y, Honda K, Yamada T, Yoshimoto S, Asai M, Okano H, Kanai Y, Tsuda
H:
SOX10
is a novel marker of acinus and intercalated duct
differentiation in salivary gland tumors: a clue to the histogenesis
for tumor diagnosis.
Mod Pathol. 2013 Apr doi: 10.1038/modpathol.2013.54. Pub Med
Ishii
K, Doi T, Inoue K, Okawada
M, Lane GJ, Yamataka A, Akazawa
C:
Correlation
between multiple RET mutations and severity of Hirschsprung's
disease.
Pediatr Surg
Int.
2013 Feb;29(2):157-63. doi: 10.1007/s00383-012-3196-1. Pub Med
Miyahara K, Kato Y, Suzuki R, Akazawa C, Tanaka N, Koga H, Doi T, Lane GJ, Yamataka A:
Anorectal neural crest derived cell behavior after the migration of vagal neural
crest derived cells is surgically disrupted:
implications for the etiology of Hirschsprung's disease.
Pediatr Surg Int.
2013 Jan;29(1):9-12. Pub Med
2012年
Suzuki N, Fukushi M, Kosaki K, Doyle AD, de Vega S, Yoshizaki
K, Akazawa C, Arikawa-Hirasawa
E, Yamada Y:
Teneurin-4 is a novel regulator of oligodendrocyte differentiation and myelination of
small-diameter axons in the CNS.
J Neurosci. 2012 Aug 22;32(34):11586-99.
Pub Med
Hara-Miyauchi C, Tsuji O,
Hanyu A, Okada S, Yasuda A, Fukano
T, Akazawa C, Nakamura M, Imamura T, Matsuzaki Y, Okano HJ, Miyawaki
A, Okano H:
Bioluminescent system
for dynamic imaging of cell and animal behavior.
Biochem Biophys Res Commun. 2012 Mar 9;419(2):188-93. Pub Med
2011年
Miyahara K, Kato Y, Koga H, Dizon
R, Lane GJ, Suzuki R, Akazawa C, Yamataka
A.
Visualization of
enteric neural crest cell migration in SOX10 transgenic mouse gut using
time-lapse fluorescence imaging.
J Pediatr
Surg. 2011 Dec;46(12):2305-8. Pub Med
Katoh H, Shibata S, Fukuda K, Sato M, Satoh E, Nagoshi
N, Minematsu T, Matsuzaki
Y, Akazawa C, Toyama Y, Nakamura M, Okano
H:
The dual origin of the peripheral olfactory system:
placode and neural crest.
Mol Brain. 2011 Sep 23;4:34. Pub Med
2010年
Miyahara K, Kato Y, Koga H, Lane GJ, Inoue T, Akazawa C, Yamataka
A:
Abnormal enteric innervation identified without histopathologic staining in aganglionic
colorectum from a mouse model of Hirschsprung's
disease.
J Pediatr
Surg. 2010 Dec;45(12):2403-7. Pub Med
Shibata S, Yasuda A, Renault-Mihara
F, Suyama S, Katoh H, Inoue
T, Inoue YU, Nagoshi N, Sato M, Nakamura M, Akazawa C, Okano H:
Sox10-Venus mice: a new tool for real-time labeling
of neural crest lineage cells and oligodendrocytes.
Mol Brain. 2010 Oct 31;3:31. Pub Med
2008年
Hashimoto M, Ishii K, Nakamura Y, Watabe K, Kohsaka S, Akazawa C:
Neuroprotective effect of sonic hedgehog up-regulated in
Schwann cells following sciatic nerve injury.
J Neurochem. 2008 Nov;107(4):918-27.
Pub Med
Liang C, Lee JS, Inn KS, Gack
MU, Li Q, Roberts EA, Vergne I, Deretic
V, Feng P, Akazawa C,
Jung JU:
Beclin1-binding UVRAG targets the class C Vps complex to coordinate autophagosome
maturation and endocytic trafficking.
Nature Cell Biology 2008 Jul;10(7):776-87. Pub Med