Meeting in Sapporo, Japan held in March, 2013

JSPS A3 Foresight Program 2013 Meeting
-Epigenetic Signatures in Gastric Carcinogenesis-

Date March 8-11, 2013
Venue Keio Plaza Hotel Sapporo

Summary

JSPS A3 Foresight Program 2013 Meeting was held on March 8-11, 2013 in Sapporo, Japan. This meeting highlighted epigenetic signatures in gastric carcinogenesis via molecular and epidemiological analyses. A total of 35 scientists (18 senior and 17 junior) from three nations attended this meeting. One senior speaker made a presentation about his study for 30 minutes. Each of 12 junior speakers was given for 20 minutes in presentation and discussion followed on further studies. During this meeting, several new collaborative research plans were proposed, and all of them were strongly supported by participants. Thus we hope that new results will be obtained soon by collaboration of researchers in three nations.

Program

Mar. 9 (Sat)

Opening remarks Yasuhito Yuasa (Tokyo Medical and Dental University, Japan)

Presentation by a senior scientist

Chairperson:
Yasuhito Yuasa		 Yong Sung Kim (Korea Research Institute of Bioscience and Biotechnology, Korea): Methylome profiling reveals neuropeptide receptors to be predominant hypermethylation targets in gastric cancers

Presentation by junior scientists (I)

Chairpersons:
Yang Zhang
Boram Choi		 Isao Oze (Aichi Cancer Center Research Institute, Japan): The effect modification of alcohol and ALDH2 polymorphism for the association of dietary folate intake with gastric cancer
Qinyan Gao (Shanghai Jiao-Tong University School of Medicine, China): Evaluation and clinical significance of the Stomach Age model – a new criterion for gastric cancer surveillance
Jeong Mo Bae (Seoul National University College of Medicine, Korea): Prognostic implication of CpG island methylator phenotype in colorectal cancers depends on tumor location

Presentation by junior scientists (II)

Chairpersons:
Naoko Hattori
Qinyan Gao		 Satoshi Yoshida (National Cancer Center Research Institute, Japan): Analysis of the role of inflammatory cells in aberrant DNA methylation induction by H. pylori infection
Linlin Cao (Peking University Health Science Center, China): Phosphorylation of KDM2A mediated by ATM facilitates DNA damage response
Keeok Haam (Korea Research Institute of Bioscience and Biotechnology, Korea): Regulation of CDX2 and its function in gastric cancer cell: genome-wide analysis of CDX2 binding in a gastric cancer cell using ChIP-seq

Presentation by junior scientists (III)

Chairpersons:
Jeong Mo Bae
Isao Oze		 Kuka Ishioka (Aichi Cancer Center Research Institute, Japan): Interaction between duration of smoking and H. pylori infection for the risk of gastric cancer
Boram Choi (Cancer Research Institute Seoul National University, Korea): Gene methylation as a novel marker in human gastric cancer
Yang Zhang (Peking University School of Oncology, Beijing Cancer Hospital & Institute, China): Helicobacter pylori associating epigenetic alternations in blood leukocyte and gastric mucosa.

Presentation by junior scientists (IV)

Chairpersons:
Shu Shimada
Keeok Haam		 Naoko Hattori (National Cancer Center Research Institute, Japan): Applications of iChmo to analyzing novel biological phenomena
Sisi Qin (Peking University Cancer Hospital and Institute, China): 5-Hydroxymethylcytosine mediates dynamic balances of methylation and demethylation of p16 CpG islands
Hee-Jin Kim (Korea Research Institute of Bioscience and Biotechnology, Korea): Hypermethylation of neuropeptide receptors in gastric cancer cells

Discussion (I): Collaborative research

R-1 Yasuhito Yuasa, Keitaro Matsuo, Taichi Shimazu, Wei-cheng You, Kai-feng Pan
R-2 Woo Ho Kim, Yoshimitsu Akiyama, Yong Sung Kim, Gyeong Hoon Kang, Yingxuan Chen, Zheming Lu, Yang Yang
R-3 Dajun Deng, Toshikazu Ushijima, Xianzi Wen
R-4 Hiroshi Fukamachi, Se Jin Jang, Han-Kwang Yang

Mar. 10 (Sun)

Discussion (II): Summary presentation and discussion

General discussion by all the participants