口腔放射線腫瘍学分野業績集

Sakimoto, I., Ohta, K., Yamazaki, T., Ohtani, S., Sahara, H., Sugawara, F., Sakaguchi, K., and Miura, M.: alpha-Sulfoquinovosyl monoacylglycerol is a potent radiosensitizer targeting tumor angiogenesis. Cancer Res., 66, 2287-2295 (2006).

Watanabe, H., Murata, Y., Miura, M., Hasegawa, M., Kawamoto, T., and Shibuya, H.: in-vivo Visualization of radiation-induced apoptosis using 125I-annexin V. Nucl. Med. Commun. 27, 81-89 (2006).

Ihara, N., Shibuya, H., Yoshimura, R., Oota, S., Miura, M., and Watanabe, H. Interstitial brachytherapy for stage III squamous cell carcinoma of the mobile tongue; The relationship between sub-stages and prognostic factors. Acta Oncol. 44, 709-716 (2005).

Kaneko, H., Igarashi, K., Kataoka, K., and Miura M. : Heat shock induces phosphorylation of histone H2AX in mammalian cells. Biochem. Biophys. Res. Commun. 328, 1101-1106 (2005).

Kuribayashi, A., Kataoka, K., Kurabayashi, T., and Miura, M. : Evidence that basal activity, but not transactivation, of the epidermal growth factor receptor tyrosine kinase is required for insulin-like growth factor I-induced activation of extracellular signal-regulated kinase in oral carcinoma cells. Endocrinology 145, 4976-4984 (2004).

Watanabe, H., T. Kurabayashi, and Miura, M. : Inhibition of the extracellular signal-regulated kinase (ERK) pathway and the induction of radioresistance in rat 3Y1 cells. Int. J. Radiat. Biol. 80, 451-456 (2004).

Hoshina, M., Shibuya, H., Kubo, H. D., Miura, M., Ohashi, I., Yoshimura, R., and Oota, S. : Determination of depth of 50% maximum ionization, I₅₀, for electron beams by divided difference methods. Med. Phys. 31, 2068-2074 (2004).

Kataoka, K., Yu, D., and Miura, M. : Activation of the phosphatidylinositol-3' kinase pathway and DNA synthesis by a mutant insulin-like growth factor I receptor lacking the NPXY motif. J. Endocrinol. 181, 139-146 (2004).

Kataoka, K. and Miura, M. : Insulin-like growth factor I receptor does not contribute to heat shock-induced activation of Akt and extracellular signal-regulated kinase (ERK) in mouse embryo fibroblasts. J. Radiat. Res. 45, 141-144 (2004).

Yu, D., Shibuya, H., and Miura, M. : Roles of the insulin-like growth factor I receptor C-terminus in cellular radioresistance. Biochem. Biophys. Res. Commun. 311, 174-178 (2003).

Yu, D., Watanabe, H., Shibuya, H., and Miura, M. : Redundancy of radioresistant signaling pathways originating from insulin-like growth factor I receptor. J. Biol. Chem. 278, 6702-6709 (2003).

Nakagawa, T., Shibuya, H., Yoshimura, R., Miura, M., Okada, N., Kishimoto, S., Amagasa, M., Omura, K. : Neck node metastasis after successful brachytherapy for early stage tongue carcinoma. Radiother. Oncol. 68, 129-135 (2003).

Imoto, I., Tsuda, H., Hirasawa, A., Miura, M., Sakamoto, M, Hirohashi, S., and Inazawa, J. : Expression of cIAP1, a target for 11q22 amplification, correlates with resistance of cervical cancers to radiotherapy. Cancer Res. 62, 4860-4866 (2002).

Watanabe, H., Yu, D., Sasaki, T., Shibuya, H., Hosoi, Y., Asada, M., Komatsu, K, and Miura, M. : Insulin-like growth factor I receptor is expressed at normal levels in Nijmegen breakage syndrome cells. Biochem. Biophys. Res. Commun. 296, 62-66 (2002).

Yu, D., Watanabe, H., Shibuya, H., and Miura, M. : The phosphatidylinositol-3 kinase pathway is not essential for insulin-like growth factor I receptor-mediated clonogenic radioresistance. J. Radiat. Res. 43, 325-329 (2002).

Yoshimura, R., Shibuya, H., Ogura, I., Miura, M., Amagasa, T., Enomoto, S., and Kishimoto, S. : Trimodal combination therapy for maxillary sinus carcinoma. Int. J. Radiat. Oncol. Biol. Phys. 53, 656-663 (2002).

Yamamoto, E., Shibuya,H., Yoshimura,R., and Miura,M. : Site specific dependency of second primary cancer in early stage head and neck squamous cell carcinoma. Cancer 94, 2007-2014 (2002).

Tezuka, M., Watanabe, H., Nakamura, S., Yu, D., Aung, W., Sasaki, T., Shibuya, H., and Miura, M. : Antiapoptotic activity is dispensable for insulin-like growth factor-I receptor-mediated clonogenic radioresistance after gamma-irradiation. Clin. Cancer Res. 7, 3206-3214 (2001).

Miura, M., Watanabe, H., Sasaki, T., Tatsumi, K., and Muto, M. : Dynamic changes in subnuclear NP95 location during the cell cycle and its spatial relationship with DNA replication foci. Exp. Cell Res. 263, 202-208 (2001).

Miura, M., Watanabe, H., Okochi, K., Sasaki, T., and Shibuya, H. : Biological response to ionizing radiation in mouse embryo fibroblasts with a targeted disruption of the DNA polymerase beta gene. Radiat. Res. 153, 773-780 (2000).

Yoshimura, R., Shibuya, H., Hoshina, M., Akaike, H., Takeda, M., Fukuda, H., Hoshi, A., and Miura, M. : Successful interstitial treatment for bilateral tongue cancer. Br. J. Radiol. 72, 812-814 (1999).

Watanabe, H., Miura, M., and Sasaki, T. : Differential effects of the insulin-like growth factor I receptor on radiosensitivity and spontaneous necrosis formation of human glioblastoma cells grown in spheroids. Exp. Cell Res. 50, 99-111 (1999).

Miura, M., Takeda, M., Sasaki, T., Inoue, T., Nakayama, T., Fukuda, H., Hoshi, A., Hoshina, M., and Shibuya, H. : Factors affecting mandibular complications in low dose-rate brachytherapy for oral tongue carcinoma with special reference to spacer. Int. J. Radiat. Oncol. Biol. Phys. 41, 763-770 (1998).

Miura, M. and Baserga, R. : The tyrosine residue at 1250 of the insulin-like growth factor I receptor is required for ligand-mediated internalization. Biochem. Biophys. Res. Commun. 239, 182-185 (1997).

Nakamura, S., Watanabe, S., Miura, M., and Sasaki, T. : Effect of the insulin-like growth factor I receptor on ionizing radiation-induced cell death in mouse embryo  fibroblasts. Exp. Cell Res. 235, 287-294 (1997).

Wang, Y., Cheong, N., Miura, M., and Iliakis, G. : Overexpression of insulin-like growth factor (IGF)-I receptor enhances inhibition of DNA replication in mouse cells exposed to x-rays. Radiat. Environ. Biophys. 36, 117-123 (1997).

Miura, M. and Sasaki, T. : Effect of XPA gene mutations on UV-induced immunostaining of PCNA in fibroblasts from xeroderma pigmentosum group A patients. Mutat. Res. (DNA Repair) 364, 51-56 (1996).

Miura, M., Nakamura, S., Sasaki, T., Takasaki, Y., Shiomi, T., and Yamaizumi, M. : Roles of XPG and XPF/ERCC1 endonucleases in UV-induced immunostaining of PCNA in fibroblasts. Exp. Cell Res. 226, 126-132 (1996).

Hongo, A., D'ambrosio, C., Miura, M., Morrione, A., and Baserga, R. : Mutational analysis of the mitogenic and transforming activities of the insulin-like growth factor I receptor. Oncogene 12, 1231-1238 (1996).

Miura, M., Sasaki, T., and Takasaki, Y. : Characterization of X-ray-induced immunostaining of PCNA in human diploid fibroblasts. Radiat. Res. 145, 73-78 (1996).

Miura, M., Surmacz, E., Burgaud, J-L., and Baserga, R. : Different effects on mitogenesis and transformation of a mutation at tyrosine 1251 of the insulin-like growth factor I receptor. J. Biol. Chem. 270, 22639-22644 (1995).

Miura, M., Li, S., and Baserga, R. : Effect of a mutation at tyrosine 950 of the insulin-like growth factor I receptor on the growth and transformation of cells. Cancer Res. 55, 663-667 (1995).

Li, S., Ferber, A., Miura, M., and Baserga, R. : Mitogenicity and transforming ability of the insulin-like growth factor I receptor with mutations in the tyrosine kinase domain. J. Biol. Chem. 269, 32558-32564 (1994).

Coppola, D., Ferber, A., Miura, M., Sell, C., D'Ambrosio, C., Rubin, R., and Baserga, R. : A functional insulin-like growth factor I receptor is required for the mitogenic and transforming activities of the epidermal growth factor receptor. Mol. Cell. Biol. 14, 4588-4595 (1994).

Sell, C., Dumenil, G., Devaud, C., Miura, M., Coppola, D., Efstratiadis, A., and Baserga, R. : Effect of a null mutation of insulin-like growth factor I receptor gene on growth and transformation of mouse embryo fibroblasts. Mol. Cell. Biol. 14, 3604-3612 (1994).

Miura, M., Li, S, Dumenil, G., and Baserga, R. : Platelet-derived growth factor-induced expression of messanger RNA for the proliferating cell nuclear antigen (PCNA) requires a functional receptor for the insulin-like growth factor I. Cancer Res. 54, 2472-2477 (1994).

Ambrose, D., Resnicoff, M., Coppola, D., Sell, C., Miura, M., Jameson, S., Baserga, R., and Rubin, R. : Growth regulation of human glioblastoma T98G cells by insulin-like growth factor-1 and its receptor. J. Cell. Physiol. 159, 92-100 (1994).

Yoshinouchi, M., Miura, M., Gaozza, E., Li, S., and Baserga, R. : Basic fibroblast growth factor stimulates DNA synthesis in cells overexpressing the insulin-like growth factor I receptor. Mol. Endocrinol. 7, 1161-1168 (1993).

Miura, M., Domon, M., Sasaki, T., Kondo, S., and Takasaki, Y. : Restoration of proliferating cell nuclear antigen (PCNA) complex formation in xeroderma pigmentosum group A cells following cis-diamminedichloroplatinum(II) treatment by cell fusion with normal cells. J. Cell. Physiol. 152, 639-645 (1992).

Miura, M., Domon, M., Sasaki, T., and Takasaki, Y. : Induction of proliferating cell nuclear antigen (PCNA) complex formation in quiescent fibroblasts from a xeroderma pigmentosum patient. J. Cell. Physiol. 150, 370-376 (1992).

Miura, M., Domon, M., Sasaki, T., Kondo, S., and Takasaki, Y. : Two types of proliferating cell nuclear antigen (PCNA) complex formation in quiescent normal and xeroderma pigmentosum group A fibroblasts following ultraviolet light (UV) irradiation. Exp. Cell Res. 201, 541-544 (1992).

Miura, M. and Sasaki, T. : Role of glutathione in the intrinsic radioresistance of cell lines from a mouse squamous cell carcinoma. Radiat. Res. 126, 229-236 (1991).

Miura, M. and Sasaki, T. : Relationship between radiosensituvity and metallothionein content in clones from a mouse squamous cell carcinoma. Radiat. Res.123, 171 − 175 (1990).